Page last updated: 2024-08-05 10:34:33

ketone body

A carbonyl compound produced as a water-soluble byproduct when fatty acids are broken down for energy in the liver. There are three endogenous ketone bodies: acetone, acetoacetic acid, and (R)-3-hydroxybutyric acid; others may be produced as a result of the metabolism of synthetic triglycerides.

ChEBI ID: 73693

Members (4)

MemberDefinitionRole
3-hydroxybutyric acidThe R-enantiomer of 3-hydroxybutyric acid. Involved in the synthesis and degradation of ketone bodies, it can be used as an energy source by the brain during hypoglycaemia, and for the synthesis of biodegradable plastics. It is a sex pheremone in the European spider Linyphia triangularis.(R)-3-hydroxybutyric acid
acetoacetic acidA 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.acetoacetic acid
acetoneA methyl ketone that consists of propane bearing an oxo group at C2.acetone
beta-hydroxyvaleric acidA short-chain fatty acid that is valeric acid in which one of the methylene hydrogens at position 3 has been replaced by a hydroxy group.3-hydroxypentanoic acid

Research

Studies (8,701)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,755 (43.16)18.7374
1990's1,019 (11.71)18.2507
2000's1,543 (17.73)29.6817
2010's1,811 (20.81)24.3611
2020's573 (6.59)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials135 (1.45%)5.53%
Reviews195 (2.10%)6.00%
Case Studies139 (1.50%)4.05%
Observational1 (0.01%)0.25%
Other8,822 (94.94%)84.16%