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agrochemical

An agrochemical is a substance that is used in agriculture or horticulture.

ChEBI ID: 33286

Members (148)

MemberDefinitionClass
1-methylcyclopropeneA member of the class of cyclopropenes that is cyclopropene in which the hydrogen at position 1 has been replaced by a methyl group. A gas at room temperture and pressure, it is a (synthetic) ethylene perception inhibitor and is used to prolong the life of cut and potted flowers, other ornamental plants, and fruit.1-methylcyclopropene
2,4-dichlorophenoxyacetic acidA chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.2,4-D
2,6-diisopropylnaphthaleneA member of the class of napthalenes that is naphthalene which is substituted by an isopropyl group at positions 2 and 6. It is a plant growth regulator which inhibits the sprouting of potatoes during storage.2,6-diisopropylnaphthalene
4-(2,4-dichlorophenoxy)butyric acidA monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a 2,4-dichlorophenoxy group. A selective post-emergence herbicide.2,4-DB
acephateA phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group.acephate
acifluorfenA member of the class of benzoic acids that is 2-nitrobenzoic acid in which the hydrogen at position 5 is replaced by a 2-chloro-4-(trifluoromethyl)phenoxy group. It is a herbicide used for the post-emergence control of a variety of annual broadleaf weeds.acifluorfen
aclonifenA primary amino compound that is aniline in which the phenyl group has been substituted at positions 2, 3, and 6 by chlorine, phenoxy, and nitro groups, respectively. A protoporphyrinogen oxidase (PPO) inhibitor, it is used as a herbicide against a broad range of weeds in a wide range of crops.aclonifen
afidopyropenAn organic heterotetracyclic compound that is 1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-benzo[f]pyrano[4,3-b]chromen-11-one which is substituted by methyl groups at positions 4, 6a, and 12b; hydroxy groups at positions 3, 6, and 9; and a cyclopropycarbonyloxymethyl group and a cyclopropylcarbonyloxy group at positions 17 and 18 respectively, and a pyridin-3-yl group at position 14 (the (3S,4R,4aR,6S,6aS,12R,12aS,12bS stereoisomer). It is an insecticide that is effective against sucking insects on fruit, vegetables and nuts.afidopyropen
alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile)A beta-diketone and nitrile resulting from the the degradation of the isoxazole ring of isoxaflutole. The active herbicide of the proherbicide isoxaflutole.2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione
aminocarbA carbamate ester that is phenyl methylcarbamate substituted by a dimethylamino group at position 4 and a methyl group at position 3.aminocarb
asulamA carbamate ester that is methyl carbamate substituted by a (4-aminophenyl)sulfonyl group at the nitrogen atom. A dihydropteroate synthase inhibitor, it is used (normally as the corresponding sodium salt, asulam-sodium) as a herbicide, mainly for killing bracken.asulam
azamethiphosazamethiphos
azinphos ethylazinphos-ethyl
azinphosmethylA member of the class of benzotriazines that is 1,2,3-benzotriazine substituted by an oxo group at position 4 and a [(dimethoxyphosphorothioyl)sulfanyl]methyl group at position 3.azinphos-methyl
bay 93820isocarbophos
bendiocarbbendiocarb
benefinA tertiany amino compound that is 2,6-dinitro-4-(trifluoromethyl)aniline in which the hydrogens attached to the aniline nitrogen have been replaced by one ethyl and one butyl group. It is used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops.benfluralin
benfuracarbbenfuracarb
bicucullineA benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.bicuculline
bpmcA carbamate ester obtained by the formal condensation of 2-sec-butylphenol with methylcarbamic acid.fenobucarb
cadusafoscadusafos
cafenstrolecafenstrole
carbarylA carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid.carbaryl
carbofurancarbofuran
carvacrolA phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1).carvacrol
chlorfenvinphoschlorfenvinfos
chlorimuron ethylAn ethyl ester resulting from the formal condensation of the carboxy group of chlorimuron with ethanol. A proherbicide for chloimuron, it is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops.chlorimuron-ethyl
chlorpyrifosAn organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.chlorpyrifos
chlorpyrifos-methylAn organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.chlorpyrifos-methyl
chlorsulfuronAn N-sulfonylurea that is N-carbamoyl-2-chlorobenzenesulfonamide in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used for the control of broadleaf weeds in wheat, barley and oats.chlorsulfuron
chlortoluronA member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a 3-chloro-4-methylphenyl group. A herbicide that is non-toxic to honeybees but moderately toxic to mammals, birds, earthworms and most aquatic organisms.chlorotoluron
clodinafop-propargylA carboxylic ester resulting from the formal condensation of the carboxy group of clodinafop with the hydroxy group of prop-2-yn-1-ol. It is widely used as a herbicide for the control of annual grass weeds in cereal crops.clodinafop-propargyl
clomazoneAn isoxazolidinone that is 1,2-oxazolidin-3-one substituted by a 2-chlorobenzyl group at position 2 and two methyl groups at position 4.clomazone
cloransulam-methylThe methyl ester of cloransulam. An inhibitor of acetohydroxyacid synthase (AHAS), it prevents the synthesis of amino acids in plants and is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. It is not approved for use within the European Area.cloransulam-methyl
coumaphoscoumaphos
cronetonethiofencarb
cuprous chlorideAn inorganic chloride of copper in which the metal is in the +1 oxidation state.copper(I) chloride
cyanophoscyanophos
cyenopyrafenA member of the class of pyrazoles that is ethene in which the hydrogens at position 1 have been replaced by p-tert-butylphenyl and cyano groups, while the hydrogens at position 2 have been replaced by pivaloyloxy and 1,3,4-trimethylpyrazol-5-yl groups (the E isomer). A proacaricide (by hydrolysis of the pivalate ester linkage to give the corresponding enol), it was formerly used for the control of mites in fruit, vegetables and tea.cyenopyrafen
cyfluthrinA carboxylic ester obtained by formal condensation between 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (4-fluoro-3-phenoxyphenyl)(hydroxy)acetonitrile.cyfluthrin
cyhalothrinA carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.cyhalothrin
cypermethrinA carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.cypermethrin
cyphenothrincyphenothrin
decamethrinA cyclopropanecarboxylate ester obtained by formal condensation between 3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol. It is the active insecticide of the proinsecticide tralomethrin.deltamethrin
deltanitfurathiocarb
demeton-s-methyldemeton-S-methyl
desmediphamA carbamate ester that is phenylcarbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(ethoxycarbonyl)amino]phenyl group. It is an agrochemical used as a herbicide.desmedipham
diazinonA member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4.diazinon
dibutylaminosulfenylcarbofurancarbosulfan
dicambaA methoxybenzoic acid that is O-methylsalicylic acid substituted by chloro groups at positions 3 and 6.dicamba
dichlobanilA nitrile that is benzonitrile which is substituted by chlorines at positions 2 and 6. A cellulose synthesis inhibitor, it is used as a pre-emergent and early post-emergent herbicide.2,6-dichlorobenzonitrile
dicrotophosdicrotophos
dimethoateA monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.dimethoate
dimethoxonomethoate
dinitrofluorobenzeneThe organofluorine compound that is benzene with a fluoro substituent at the 1-position and two nitro substituents in the 2- and 4-positions.1-fluoro-2,4-dinitrobenzene
disulfotonAn organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate.disulfoton
endosulfanA cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.endosulfan
ethionAn organic thiophosphate that is S,S'-methanediyl bis[dihydrogen (phosphorodithioate)] in which all the hydroxy groups have been converted to their corresponding ethyl esters respectively. Ethion is an organophosphate insecticide with inhibitory activity towards the enzyme acetylcholinesterase ( EC 3.1.1.7).ethion
ethoprophosethoprophos
famophosfamphur
fenamiphosfenamiphos
fenitrothionAn organic thiophosphate that is O,O-dimethyl O-phenyl phosphorothioate substituted by a methyl group at position 3 and a nitro group at position 4.fenitrothion
fenpropathrin, (+-)-isomerA cyclopropanecarboxylate ester obtained by formal condensation between 2,2,3,3-tetramethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.fenpropathrin
fensulfothionfensulfothion
fenthionAn organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.fenthion
fenuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of weeds in beetroot as well as various vegetable and ornamental crops.fenuron
fluazaindolizineA member of the class of imidazopyridines that is the amide formed from the formal condensation of the carboxy group of 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid with the sulfonamide nitrogen of 2-chloro-5-methoxybenzene-1-sulfonamide.fluazaindolizine
fluensulfoneA member of the class of 1,3-thiazoles carrying 3,4,4-trifluorobut-3-ene-1-sulfonyl and chloro substituents at positions 2 and 5 respectively. A nematicide that is effective against a number of plant parasitic nematodes in a range of agricultural and horticultural crops.fluensulfone
fluometuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-(trifluoromethyl)phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of broadleaf weeds and annual grasses in cotton.fluometuron
fluvalinatefluvalinate
fomesafenAn N-sulfonylcarboxamide that is N-(methylsulfonyl)benzamide in which the phenyl ring is substituted by a nitro group at position 2 and a 2-chloro-4-(trifluoromethyl)phenoxy group at position 5. A protoporphyrinogen oxidase inhibitor, it was specially developed for use (generally as the corresponding sodium salt, fomesafen-sodium) for post-emergence control of broad-leaf weeds in soya.fomesafen
fonofosfonofos
formetanateformetanate
fosthiazatefosthiazate
glyoxalThe dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons.glyoxal
glyphosateA phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).glyphosate
haloxyfop-P-methylA methyl 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate that has R configuration. It is a proherbicide (by hydrolysis of the methyl ester) for the herbicide haloxyfop-P, the most active enantiomer of the racemic herbicide haloxyfop.haloxyfop-P-methyl
heptachlorA cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations.heptachlor
heptenophosheptenophos
isofenphosisofenphos
isoprocarbisoprocarb
isoproturonA member of the class of phenylureas that is 1,1-dimethylurea substituted by a p-cumenyl group at position 3. A selective, systemic herbicide used to control annual grasses and broadleaf weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.isoproturon
isoxaflutoleA member of the class of isoxazoles that is 1,2-oxazole substituted by a 2-(methanesulfonyl)-4-(trifluoromethyl)benzoyl group and a cyclopropyl group at positions 4 and 5, respectively. It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor which is used as a herbicide for weed control in maize and sugarcane.isoxaflutole
lenacilA cyclopentapyrimidine that is 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione substituted by a cyclohexyl group at position 3.lenacil
linuronA member of the class of phenylureas that is N-methyl urea substituted by a methoxy group at position 1 and a 3,4-dichlorophenyl group at position 3.linuron
mecarbamAn organic thiophosphate that is O,O-diethyl hydrogen phosphorodithioate in which the hydrogen attached to a sulfur is replaced by a 2-[(ethoxycarbonyl)(methyl)amino]-2-oxoethyl group.mecarbam
mefenoxamA methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate that is the more active R-enantiomer of metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops.metalaxyl-M
mepiquatA quaternary ammonium ion has that has two methyl groups and a pentamethylene-1,5-diyl group attached to the nitrogen. Its salts are used as plant growth inhibitors.mepiquat
methamidophosAn organic thiophosphate resulting from the N-deacylation of the proinsecticide acephate.methamidophos
methidathionmethidathion
methiocarbA carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of methylcarbamic acid.methiocarb
methomylA carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime.methomyl
methoxuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-chloro-4-methoxyphenyl group while the other is substituted by two methyl groups. It is a plant growth regulator and a pre- and post-emergence herbicide used for the control of grasses and broad-leaved weeds in carrots and cereals (e.g. wheat, barley and rye).metoxuron
methyl bensulfuronThe methyl ester of bensulfuron. An acetolactate synthase inhibitor, it is used as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. It is not licensed for use within the UK.bensulfuron-methyl
methyl parathionA C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4.parathion-methyl
metolcarbmetolcarb
metribuzinA member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, tert-butyl group at position 6 and a methylsulfanyl group at position 3.metribuzin
molinateA member of the class of azepanes that is azepane in which the nitrogen is substituted by an (ethylsulfanyl)carbonyl group, -C(=O)SEt. A thiocarbamate herbicide not approved for use in the U.S. or European Union, it is used control grass weeds in rice paddies.molinate
monocrotophosAn alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate.monocrotophos
n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamideA member of the class of triazoles that is 5-oxo-1,2,4-triazole which is substituted at positions 1, 3, and 4 by 2,4-dichloro-5-[(methylsulfonyl)amino]phenyl, methyl, and difluoromethyl groups, respectively. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. Not approved for use within the European Union.sulfentrazone
naledAn dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use within the European Union.naled
nitarsoneAn organoarsonic acid where the organyl group is 4-nitrophenyl.nitarsone
nitrapyrinA chloropyridine that is 2-chloropyridine which is substituted by a trichloromethyl group at position 6. It is a nitrification inhibitor that is co-applied with nitrogen fertilizer in agroecosystems.nitrapyrin
norflurazoneA pyridazinone that is pyridazin-3(2H)-one which is substituted at positions 2, 4, and 5 by m-(trifluoromethyl)phenyl, chloro, and methylamino groups, respectively. A pre-emergence herbicide used to control grasses and broad-leafed weeds in a variety of crops. Not approved for use within the European Union.norflurazon
oryzalinA sulfonamide that is benzenesulfonamide substituted at positions 3 and 5 by nitro groups and at position 4 by a dipropylamino group.oryzalin
oxadixylAn oxazolidinone that is N-(2,6-dimethylphenyl)-2-methoxyacetamide in which the amide hydrogen is replaced by a 2-oxo-1,3-oxazolidin-3-yl group. A systemic fungicide used to treat seeds of a variety of food crops, as well as lawns.oxadixyl
parathionparathion
pendimethalinA member of the class of substituted anilines that is N-(pentan-3-yl)aniline bearing two additional nitro substituents at positions 2 and 6 as well as two methyl substituents at positions 3 and 4. A herbicide used to control most annual grasses and many annual broad-leaved weeds.pendimethalin
permethrinA cyclopropanecarboxylate ester in which the esterifying alcohol is 3-phenoxybenzyl alcohol and the cyclopropane ring is substituted with a 2,2-dichlorovinyl group and with gem-dimethyl groups.permethrin
phenthoate, (+-)-isomerAn organic thiophosphate that is ethyl mandelate in which the hydroxy group has been replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.phenthoate
phenylphosphonothioic acid, 2-ethyl 2-(4-nitrophenyl) esterEPN
phoratephorate
phosaloneA member of the class of 1,3-benzoxazoles carrying a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2 and a chloro group at position 6. It is an organothiophosphate insecticide.phosalone
phosmetphosmet
pinoxadenA pyrazolooxadiazepine that is 7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin which is substituted at positions 8 and 9 by 2,6-diethyl-4-methylphenyl and pivaloyloxy groups, respectively. A pro-herbicide (by hydrolysis of the pivalate ester to give the corresponding enol), it is used for control of grass weeds in cereal crops.pinoxaden
pirimicarbAn aminopyrimidine that is N,N,4,5-tetramethylpyrimidin-2-amine substituted by a (dimethylcarbamoyl)oxy group at position 4.pirimicarb
pirimiphos methylAn organic thiophosphate that is O,O-dimethyl O-pyrimidin-4-yl phosphorothioate substituted by a methyl group at position 6 and a diethylamino group at position 2.pirimiphos-methyl
profenofosprofenofos
pronamideA member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops.propyzamide
propetamphospropetamphos
propoxurA carbamate ester that is phenyl methylcarbamate substituted at position 2 by a propan-2-yloxy group.propoxur
prothiophosAn organic thiophosphate that is the 2,4-dichlorophenyl ester of O-ethyl S-propyl dithiophosphoric acid.prothiofos
pydrin, (s-(r*,r*))-isomeresfenvalerate
pyraclofospyraclofos
pyridafenthionpyridaphenthion
quinalphosquinalphos
quincloracA quinolinemonocarboxylic acid that is quinoline-8-carboxylic acid in which the hydrogens at positions 3 and 7 have been replaced by chlorines. It is used (particularly as its dimethylamine salt, known as quinclorac-dimethylammonium) as a (rather persistent) herbicide for the post-emergence control of weeds in rice, grass and turf. It is not approved for use within the European Union.quinclorac
quinomethionateA dithioloquinoxaline that results from the formal condensation of 6-methylquinoxaline-2,3-dithiol with phosgene. It has been used as a fungicide and acaricide for the control of mites and powdery mildew on citrus, vegetables, and walnuts, but is not approved for use in the EU.quinomethionate
raiserflurochloridone
resmethrinresmethrin
roxarsoneAn organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.roxarsone
s 53482A benzoxazine that is N-(prop-2-yn-1-yl)-2H-1,4-benzoxazin-3(4H)-one which is substituted at position 6 by a 1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl group and at position 7 by a fluorine. A protoporphyrinogen oxidase inhibitor, it is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops.flumioxazin
sulfoteppsulfotep
sulprofossulprofos
tembotrioneAn aromatic ketone that is 2-benzoylcyclohexane-1,3-dione in which the phenyl group is substituted at positions 2, 3, and 4 by chlorine, (2,2,2-trifluoroethoxy)methyl, and methylsulfonyl groups, respectively. It is a post-emergence herbicide used (particularly in conjunction with the herbicide safener cyprosulfamide) for the control of a wide range of broad-leaved and grassy weeds in corn and other crops.tembotrione
temefosAn organic sulfide that is diphenyl sulfide in which the hydrogen at the para position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group.temephos
terbufosterbufos
tetrachlorvinphostetrachlorvinphos
thifensulfuron methylA methyl ester resulting from the formal condensation of the carboxy group of thifensulfuron with methanol. It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds.thifensulfuron-methyl
thiometonthiometon
tioxazafenA 1,2,4-oxadizole in which the hydrogens at positions 3 and 5 have been replaced by phenyl and thiophen-2-yl groups, respectively. It is used as a broad spectrum nematicidal seed treatment.tioxazafen
tolfenpyradAn aromatic amide obtained by formal condensation of the carboxy group of 4-chloro-3-ethyl-1-methylpyrazole-5-carboxylic acid with the amino group of 1-[4-(4-methylphenoxy)phenyl]methylamine.tolfenpyrad
triasulfuronAn N-sulfonylurea that is N-[o-(2-chloroethoxy)phenyl]sulfonylurea in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used to control broad-leaved weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life.triasulfuron
triazophostriazophos
trichlorfonA phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.trichlorfon
triclopyrA monocarboxylic acid that is (pyridin-2-yloxy)acetic acid substituted by chloro groups at positions 3, 5 and 6. It is an agrochemical used as a herbicide.trichlopyr
trifluralinA substituted aniline that is N,N-dipropylaniline substituted by a nitro groups at positions 2 and 6 and a trifluoromethyl group at position 4. It is an agrochemical used as a pre-emergence herbicide.trifluralin
triflusulfuron-methylA methyl ester resulting from the formal condensation of the carboxy group of triflusulfuron with methanol. A proherbicide for triflusulfuron.triflusulfuron-methyl

Research

Studies (78,624)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199029,616 (37.67)18.7374
1990's11,120 (14.14)18.2507
2000's14,338 (18.24)29.6817
2010's16,419 (20.88)24.3611
2020's7,131 (9.07)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials1,789 (1.95%)5.53%
Reviews3,805 (4.14%)6.00%
Case Studies2,011 (2.19%)4.05%
Observational120 (0.13%)0.25%
Other84,100 (91.59%)84.16%

Protein Targets (232)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency21.810616
15-lipoxygenase, partialHomo sapiens (human)Potency28.007613
67.9K proteinVaccinia virusPotency1.353923
acetylcholinesteraseHomo sapiens (human)Potency33.45544227
activating transcription factor 6Homo sapiens (human)Potency39.5654232
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency28.4604124
Alpha-synucleinHomo sapiens (human)Potency10.000011
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency25.285512
AR proteinHomo sapiens (human)Potency34.627212362
aryl hydrocarbon receptorHomo sapiens (human)Potency29.94503125
Ataxin-2Homo sapiens (human)Potency35.1749111
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency26.748923
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency40.7642215
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency37.152513
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency45.793015
caspase-3Cricetulus griseus (Chinese hamster)Potency64.655417
caspase-3Homo sapiens (human)Potency45.793015
Caspase-7Cricetulus griseus (Chinese hamster)Potency64.655417
Cellular tumor antigen p53Homo sapiens (human)Potency46.8039362
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency14.189224
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency30.090914
Chain A, Beta-lactamaseEscherichia coli K-12Potency28.558923
Chain A, Ferritin light chainEquus caballus (horse)Potency29.419616
Chain A, HADH2 proteinHomo sapiens (human)Potency27.4936213
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency62.777619
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency19.173318
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency15.102314
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency34.5978114
Chain B, HADH2 proteinHomo sapiens (human)Potency27.4936213
chromobox protein homolog 1Homo sapiens (human)Potency73.9088113
cytochrome P450 2C19 precursorHomo sapiens (human)Potency10.000011
cytochrome P450 2C9, partialHomo sapiens (human)Potency11.0893113
cytochrome P450 2D6Homo sapiens (human)Potency19.267617
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency9.0490236
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency10.5610215
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency41.3927146
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency1.258911
DNA dC->dU-editing enzyme APOBEC-3F isoform aHomo sapiens (human)Potency2.990412
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency68.145616
DNA polymerase kappa isoform 1Homo sapiens (human)Potency24.786619
estrogen nuclear receptor alphaHomo sapiens (human)Potency35.984512323
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency44.1960253
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency41.38389305
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency19.4574111
farnesoid X nuclear receptorHomo sapiens (human)Potency39.4950571
Fumarate hydrataseHomo sapiens (human)Potency42.555913
GVesicular stomatitis virusPotency11.0893113
GABA theta subunitRattus norvegicus (Norway rat)Potency9.0490118
GALC proteinHomo sapiens (human)Potency50.118711
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency9.0490118
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency9.0490118
gemininHomo sapiens (human)Potency8.5593219
GLI family zinc finger 3Homo sapiens (human)Potency31.58353113
glp-1 receptor, partialHomo sapiens (human)Potency19.118012
GLS proteinHomo sapiens (human)Potency11.220211
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency34.6286571
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency44.5509127
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)Potency31.622811
Glycoprotein hormones alpha chainHomo sapiens (human)Potency31.622811
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency3.078313
Guanine nucleotide-binding protein GHomo sapiens (human)Potency18.746616
heat shock protein beta-1Homo sapiens (human)Potency44.5901252
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency19.952612
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency28.151619
histone deacetylase 9 isoform 3Homo sapiens (human)Potency26.0178218
Histone H2A.xCricetulus griseus (Chinese hamster)Potency87.4341242
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency11.0893113
hypothetical protein, conservedTrypanosoma bruceiPotency24.961833
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency41.2683235
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency50.118712
IDH1Homo sapiens (human)Potency29.092911
importin subunit beta-1 isoform 1Homo sapiens (human)Potency44.859126
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency11.0893126
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency28.183811
Integrin alpha-IIbHomo sapiens (human)Potency10.545913
Integrin beta-3Homo sapiens (human)Potency10.545913
Interferon betaHomo sapiens (human)Potency15.0346215
interleukin 8Homo sapiens (human)Potency62.240515
isocitrate dehydrogenase 1, partialHomo sapiens (human)Potency50.118711
lamin isoform A-delta10Homo sapiens (human)Potency15.9240110
lethal factor (plasmid)Bacillus anthracis str. A2012Potency13.585515
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency27.076513
LuciferasePhotinus pyralis (common eastern firefly)Potency50.4120242
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency35.481311
Microtubule-associated protein tauHomo sapiens (human)Potency25.0087210
mitogen-activated protein kinase 1Homo sapiens (human)Potency15.1890210
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency0.316211
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency19.952611
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency40.76364161
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency21.423413
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency32.947313
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency38.4887237
Nuclear receptor ROR-gammaHomo sapiens (human)Potency29.267717
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency21.1635214
nuclear receptor subfamily 1, group I, member 2Rattus norvegicus (Norway rat)Potency12.589311
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency29.05883253
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency24.999613
ParkinHomo sapiens (human)Potency39.810711
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency94.562612
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency7.588825
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency43.9212575
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)Potency44.668411
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency30.7062552
phosphopantetheinyl transferaseBacillus subtilisPotency32.5269116
PINK1Homo sapiens (human)Potency39.810711
polyproteinZika virusPotency42.555913
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency39.810711
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency19.952611
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency28.6974110
pregnane X nuclear receptorHomo sapiens (human)Potency37.11013151
pregnane X receptorRattus norvegicus (Norway rat)Potency37.3015127
progesterone receptorHomo sapiens (human)Potency29.2731273
Rap guanine nucleotide exchange factor 4Homo sapiens (human)Potency26.528314
RAR-related orphan receptor gammaMus musculus (house mouse)Potency33.75932109
regulator of G-protein signaling 4Homo sapiens (human)Potency46.682713
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency40.46243143
retinoid X nuclear receptor alphaHomo sapiens (human)Potency29.07564133
serine-protein kinase ATM isoform aHomo sapiens (human)Potency39.810713
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency24.792017
SMAD family member 2Homo sapiens (human)Potency34.3538228
SMAD family member 3Homo sapiens (human)Potency34.3538228
Smad3Homo sapiens (human)Potency35.481311
snurportin-1Homo sapiens (human)Potency44.859126
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency21.679412
survival motor neuron protein isoform dHomo sapiens (human)Potency35.481311
TAR DNA-binding protein 43Homo sapiens (human)Potency20.245814
TDP1 proteinHomo sapiens (human)Potency24.8866238
thioredoxin glutathione reductaseSchistosoma mansoniPotency31.622811
thioredoxin reductaseRattus norvegicus (Norway rat)Potency52.305316
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency54.11263120
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency12.2778730
thyroid stimulating hormone receptorHomo sapiens (human)Potency30.37267142
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency38.779424
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency1.258911
USP1 protein, partialHomo sapiens (human)Potency48.156518
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency35.4638271
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency26.8991556
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency40.5549128
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency44.5509127
VprHuman immunodeficiency virus 1Potency33.552012
WRNHomo sapiens (human)Potency35.481311

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)IC5016.187022
14 kDa phosphohistidine phosphataseHomo sapiens (human)IC5080.000011
15-cis-phytoene desaturaseSynechococcus elongatus PCC 7942 = FACHB-805IC500.285013
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)IC5048.250011
2-dehydro-3-deoxyphosphooctonate aldolaseNeisseria meningitidis MC58Ki260.000011
3-ketoacyl-CoA synthase 18Arabidopsis thaliana (thale cress)IC500.199511
3-ketoacyl-CoA synthase 20Arabidopsis thaliana (thale cress)IC500.398111
4-hydroxyphenylpyruvate dioxygenaseArabidopsis thaliana (thale cress)Ki0.013011
Acetolactate synthase Raphanus raphanistrumIC5033.338033
Acetolactate synthase catalytic subunit, mitochondrialSaccharomyces cerevisiae S288CKi0.044913
Acetolactate synthase, chloroplasticArabidopsis thaliana (thale cress)Ki0.009422
AcetylcholinesteraseAnopheles gambiae (African malaria mosquito)IC500.112822
AcetylcholinesteraseElectrophorus electricus (electric eel)IC50145.680022
AcetylcholinesteraseHomo sapiens (human)IC5072.097544
Acetylcholinesterase Drosophila melanogaster (fruit fly)IC501.830011
Androgen receptorRattus norvegicus (Norway rat)IC5018.466012
Bile salt export pumpHomo sapiens (human)IC501,000.000011
Carbonic anhydrase 1Homo sapiens (human)Ki61.700011
Carbonic anhydrase 12Homo sapiens (human)Ki9.520011
Carbonic anhydrase 13Homo sapiens (human)Ki4.230011
Carbonic anhydrase 14Homo sapiens (human)Ki4.140011
Carbonic anhydrase 2Homo sapiens (human)Ki200.000011
Carbonic anhydrase 3Homo sapiens (human)Ki4.620011
Carbonic anhydrase 4Homo sapiens (human)Ki5.480011
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Ki5.090011
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)Ki3.410011
Carbonic anhydrase 6Homo sapiens (human)Ki2.230011
Carbonic anhydrase 7Homo sapiens (human)Ki4.680011
Carbonic anhydrase 9Homo sapiens (human)Ki6.410011
Carboxylic ester hydrolase Musca domestica (house fly)IC509.510011
Carboxylic ester hydrolase Plutella xylostella (diamondback moth)IC501,355.500022
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferaseAgrobacterium sp. CP4IC505,580.000014
CholinesteraseEquus caballus (horse)IC50410.790011
Cytochrome P450 71B1Thlaspi arvenseIC5012.000011
Fatty-acid amide hydrolase 1Homo sapiens (human)IC5030.000022
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)IC5015.000011
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)IC5015.000011
Glutamine synthetase Nicotiana tabacum (common tobacco)IC50100.000011
Glutamine synthetase Spinacia oleracea (spinach)IC50100.000011
Hormone-sensitive lipaseRattus norvegicus (Norway rat)IC500.370011
kallikrein-5 preproproteinHomo sapiens (human)IC5050.000011
perilipin-1Homo sapiens (human)IC5020.463011
perilipin-5Homo sapiens (human)IC5011.911011
Photosystem II protein D1Spinacia oleracea (spinach)IC500.080011
polyadenylate-binding protein 1Homo sapiens (human)IC5066.000024
Polyphenol oxidase 2Agaricus bisporusIC50500.000011
Prostaglandin G/H synthase 1Homo sapiens (human)IC504.000011
Protoporphyrinogen oxidaseHomo sapiens (human)Ki0.968634
Protoporphyrinogen oxidase Zea maysIC500.003211
Protoporphyrinogen oxidase, chloroplasticNicotiana tabacum (common tobacco)Ki0.030011
Protoporphyrinogen oxidase, mitochondrialNicotiana tabacum (common tobacco)Ki0.070011
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrialPisum sativum (garden pea)IC504,530.000022
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialPisum sativum (garden pea)IC504,530.000022
Secreted chorismate mutaseMycobacterium tuberculosis H37RvIC501.060011
Tubulin alpha-1A chainSus scrofa (pig)IC5040.000012
Zeta-carotene desaturase, chloroplastic/chromoplasticCapsicum annuumIC50100.000012

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
4-hydroxyphenylpyruvate dioxygenaseDaucus carota (carrot)Kd0.006011
ORF73Human gammaherpesvirus 8EC5075.000011
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)EC5013.532023

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7Homo sapiens (human)AC5050.000011
Cytochrome P450 71B1Thlaspi arvenseKs60.000011
prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)Active Concentration20.000011
UDP-glucuronosyltransferase 1A4Homo sapiens (human)Km1,500.000011