Page last updated: 2024-12-05
etridiazol
Description
Etridiazol is a fungicide that is used to control a wide range of fungal diseases in crops. It is a broad-spectrum fungicide, meaning that it is effective against a wide variety of fungal species. Etridiazol is typically applied as a seed treatment, a foliar spray, or a soil drench. The compound is thought to work by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes. Etridiazol has been shown to be effective in controlling fungal diseases in a variety of crops, including cereals, vegetables, fruits, and ornamental plants. It has also been used to control fungal diseases in turfgrass. Etridiazol is a synthetic compound that is manufactured through a multi-step process. The synthesis of etridiazol begins with the reaction of 2-chloro-4-nitroaniline with 2-methyl-2-propanol. This reaction produces 2-(2-chloro-4-nitrophenylamino)-2-methylpropan-1-ol. This compound is then reacted with 2-methyl-2-propanol to produce etridiazol. The compound is known to be toxic to aquatic organisms, and it is important to apply it in a way that minimizes the risk of environmental contamination. Etridiazol is an important fungicide for crop protection. It has been shown to be effective in controlling a wide range of fungal diseases and it is an important tool for farmers to help them protect their crops from disease.'
etridiazol: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
etridiazole : A member of the class of thiadiazoles that is 1,2,4-thiadiazole which is substituted at positions 3 and 5 by trichloromethyl and ethoxy groups, respectively. A fungicide, it has been used particularly for the control of Phytophthora and Pythium species in soils. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 17432 |
| CHEMBL ID | 3183350 |
| CHEBI ID | 81761 |
| SCHEMBL ID | 20227 |
| MeSH ID | M0063124 |
Synonyms (78)
| Synonym |
|---|
| 1,2,4-thiadiazole, 5-ethoxy-3-(trichloromethyl)- |
| wln: t5ns dnj co2 exggg |
| banrot |
| terracoat |
| olin mathieson 2,424 |
| ethazol |
| terracoat l21 |
| etmt |
| terrachlor-super x |
| 5-ethoxy-3-(trichloromethyl)-1,4-thiadiazole |
| 3-(trichloromethyl)-5-ethoxy-1,4-thiadiazole |
| ethazole (fungicide) |
| aaterra |
| nsc524929 |
| om 2424 |
| terrazole |
| truban |
| etridiazol |
| om 2425 |
| 1,4-thiadiazole, 5-ethoxy-3-(trichloromethyl)- |
| nsc-524929 |
| 2593-15-9 |
| etridiazole |
| etcmtb |
| 5-aethoxy-3-trichlormethyl-1,4-thiadiazol |
| echlomezole |
| echlomezol |
| koban |
| etridiazole, analytical standard |
| NCGC00163854-01 |
| mf-344 |
| pansoil |
| einecs 219-991-8 |
| terraflo |
| ethyl 3-trichloromethyl-1,2,4-thiadiazol-5-yl ether |
| brn 1074817 |
| dwell |
| 5-aethoxy-3-trichlormethyl-1,2,4-thiadiazol [german] |
| hsdb 1709 |
| etridiazole [bsi:iso] |
| ai3-29280 |
| 5-ethoxy-3-trichloromethyl-1,2,4-thiadiazole |
| caswell no. 428 |
| epa pesticide chemical code 084701 |
| nsc 524929 |
| planvate |
| 3-(trichloromethyl)-5-ethoxy-1,2,4-thiadiazole |
| 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole |
| NCGC00163854-02 |
| NCGC00163854-03 |
| C18460 |
| 9f8237i875 , |
| unii-9f8237i875 |
| 5-aethoxy-3-trichlormethyl-1,2,4-thiadiazol |
| dtxsid3032547 , |
| tox21_300924 |
| cas-2593-15-9 |
| NCGC00254826-01 |
| dtxcid1012547 |
| BP-10210 |
| FT-0603613 |
| AKOS015898229 |
| om-2424 |
| sanyard |
| etridiazole [iso] |
| etridiazole [hsdb] |
| SCHEMBL20227 |
| CHEBI:81761 , |
| 3-trichloromethyl-5-ethoxy-1,2,4-thiadiazole |
| ethyl 3-(trichloromethyl)-1,2,4-thiadiazol-5-yl ether # |
| etridazole |
| 5-ethoxy-3-trichloromethyl-1,2,4-thiadiazol |
| CHEMBL3183350 |
| etridiazole, pestanal(r), analytical standard |
| etridiazole 10 microg/ml in cyclohexane |
| J-016188 |
| Q1371667 |
| CAA59315 |
Research Excerpts
Overview
Etridiazole (EDZ) is a thiadiazole-containing fungicide commonly used to control fungi.
Compound-Compound Interactions
Roles (2)
| Role | Description |
|---|
| antifungal agrochemical | Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. |
| nitrification inhibitor | Any inhibitor added to nitrogen fertilizers which can reduce the rate at which ammonium is converted to nitrate. Under appropriate conditions, this can help reduce nitrogen losses through denitrification and leaching. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (4)
| Class | Description |
|---|
| aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
| thiadiazoles | |
| organochlorine compound | An organochlorine compound is a compound containing at least one carbon-chlorine bond. |
| thiadiazole antifungal agent | A compound that has significant antifungal properties whose structure contains a thiadiazole moiety. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein Targets (4)
Potency Measurements
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 24.39
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 24.39 (24.57) | | Research Supply Index | 2.64 (2.92) | | Research Growth Index | 4.40 (4.65) | | Search Engine Demand Index | 50.49 (26.88) | | Search Engine Supply Index | 4.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (7.69%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (92.31%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |