Page last updated: 2024-08-05 11:13:37

2-benzofurans

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ChEBI ID: 38831

Members (23)

MemberDefinitionRole
(3z,6alpha,7alpha)-isomer of 3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3h)-isobenzofuranoneSenkyunolide h
2',7'-dichlorofluorescein2',7'-dichlorofluorescein
3-Furan-3-yl-3a,7-dimethyl-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-one3-Furan-3-yl-3a,7-dimethyl-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-one
4,6-Dimethoxy-phthalide4,6-Dimethoxy-phthalide
5,6-dimethoxy-3H-isobenzofuran-1-one5,6-dimethoxy-3H-isobenzofuran-1-one
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-4-hexenoic acid6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-4-hexenoic acid
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester
asperfuranoneA member of the class of 2-benzofurans that is 6,7-dihydro-2-benzofuran-4(5H)-one that is substituted at positions 5 and 6 by hydroxy groups, at position 5 by a methyl group and at position 1 by a (2E,4E,6S)-4,6-dimethylocta-2,4-dienoyl group (the 5S,6R-diastereoisomer). A polyketide that was first obtained from the fungus Aspergillus nidulans by using a genomic mining approach.asperfuranone
butylidenephthalideA gamma-lactone that is phthalide substituted by a butylidene group at position 3. Isolated from Ligusticum porteri, it exhibits hypoglycemic activity.(Z)-3-butylidenephthalide
calcein amAn organic heteropentacyclic compound that is calcein in which all four carboxy group hydrogens have been substituted by (acetyloxy)methoxy groups and the hyrodgens of the two hydroxy groups have been substituted by acetyl groups. It is a a non-fluorescent probe cleaved to a fluorescent probe by non-specific intracellular esterases.calcein am
citalopramA nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
deberzatofogliflozin
fluoranfluoran
fluoresceinA xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.fluorescein (lactone form)
fraxinelloneFraxinellone
galleinA xanthene dye that is fluoran carrying four hydroxy substituents at positions 3', 4', 5' and 6'.gallein
meconinMeconine
mycophenolic acidA member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.mycophenolic acid
phthalic anhydrideThe cyclic dicarboxylic anhydride that is the anhydride of phthalic acid.phthalic anhydride
phthalideA gamma-lactone that is 1,3-dihydro-2-benzofuran in which the hydrogens at position 1 are replaced by an oxo group.2-benzofuran-1(3H)-one
sulfobromophthaleinAn organosulfonic acid that consists of phthalide bearing four bromo substituents at positions 4, 5, 6 and 7 as well as two 4-hydroxy-3-sulfophenyl groups both located at position 1.bromosulfophthalein
tetrabromophthalic anhydrideTetrabromophthalic anhydride
trimellitic anhydrideA 2-benzofuran compound having oxo groups at the 1- and 3-positions and a carboxy substituent at the 5-position; the cyclic anhydride formed from the carboxy groups at the 1- and 2-positions of trimellitic acid.trimellitic anhydride

Research

Studies (23,640)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,786 (16.02)18.7374
1990's2,835 (11.99)18.2507
2000's7,397 (31.29)29.6817
2010's7,526 (31.84)24.3611
2020's2,096 (8.87)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials3,249 (12.85%)5.53%
Reviews1,806 (7.14%)6.00%
Case Studies2,405 (9.51%)4.05%
Observational156 (0.62%)0.25%
Other17,675 (69.89%)84.16%