tetracycline and Pericoronitis

An evaluation is made of bacterial species and susceptibility to various antibiotics used in application to odontogenic infections of periapical location and in pericoronitis of the lower third molar, with the aim of optimizing the antibiotherapy of such infections and thus preventing unnecessary side effects and over-treatment.. Sixty-four patients with odontogenic infection were selected on the basis of a series of inclusion and exclusion criteria. Samples were collected from lesions under maximally aseptic conditions, avoiding oral saprophytic contamination. The samples were cultured and incubated under aerobic and anaerobic conditions, followed by bacteriological identification and antibiotic susceptibility testing.. A total of 184 bacterial strains were isolated and identified, comprising grampositive facultative anaerobes (68%), gramnegative strict anaerobes (30%) and grampositive facultative anaerobes (2%). Regardless of the origin of the odontogenic infection, the causal bacteria yielded the best results in terms of increased sensitivity and lesser resistance with amoxicillin / clavulanate and amoxicillin, respectively (p<0.05).. There are increasingly numerous reports in the literature of growing bacterial resistance to antibiotics in infectious processes affecting non-buccodental territories. This same tendency has not been observed in relation to oral infections, though important resistance has been documented for certain concrete antibiotics. According to our results, the common-use antibiotics with the greatest sensitivity and lowest resistance were shown to be amoxicillin/clavulanate followed by amoxicillin alone.

Topics: Acetamides; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria, Anaerobic; Clindamycin; Drug Resistance, Bacterial; Female; Focal Infection, Dental; Humans; Linezolid; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Molar, Third; Oxazolidinones; Periapical Periodontitis; Pericoronitis; Tetracycline

Four hundred twenty-four mandibular third molar extractions of varied surgical difficulty were evaluated for the occurrence of alveolar osteitis. In 219 of these sockets, tetracycline powder was placed immediately after the tooth was removed. This resulted in a significant reduction in the incidence of alveolar osteitis from 28.7% to 14.6%. There was also a positive correlation between the rate of alveolar osteitis and the increasing depth of the impaction and the degree of surgical difficulty.

Topics: Dexamethasone; Dry Socket; Humans; Molar, Third; Pericoronitis; Powders; Tetracycline; Tooth Eruption; Tooth Extraction

Topics: Anti-Bacterial Agents; Antifungal Agents; Candidiasis, Oral; Endocarditis, Bacterial; Erythromycin; General Practice, Dental; Humans; Immunosuppression Therapy; Injections, Intramuscular; Jaw Fractures; Mouth Diseases; Osteomyelitis; Penicillins; Periapical Abscess; Pericoronitis; Radiotherapy; Tetracycline

Topics: Anti-Bacterial Agents; Humans; Penicillins; Pericoronitis; Tetracycline; Time Factors