An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
ChEBI ID: 130181
Member | Definition | Class |
---|---|---|
calmidazolium | An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein. | calmidazolium |
calmidazolium | The organic choride salt of calmidazolium. | calmidazolium chloride |
pentamidine | A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. | pentamidine |
trifluoperazine | A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. | trifluoperazine |
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
---|---|---|
pre-1990 | 2,895 (47.51) | 18.7374 |
1990's | 1,677 (27.52) | 18.2507 |
2000's | 734 (12.04) | 29.6817 |
2010's | 636 (10.44) | 24.3611 |
2020's | 152 (2.49) | 2.80 |
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
---|---|---|
Trials | 293 (4.39%) | 5.53% |
Reviews | 287 (4.30%) | 6.00% |
Case Studies | 517 (7.75%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5,577 (83.56%) | 84.16% |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
15-lipoxygenase, partial | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
67.9K protein | Vaccinia virus | Potency | 13.3622 | 2 | 6 |
acid sphingomyelinase | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
alpha-galactosidase | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
Alpha-synuclein | Homo sapiens (human) | Potency | 13.1374 | 1 | 3 |
apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 11.2202 | 1 | 1 |
ATAD5 protein, partial | Homo sapiens (human) | Potency | 25.1456 | 3 | 7 |
Ataxin-2 | Homo sapiens (human) | Potency | 28.7968 | 1 | 2 |
ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 15.1014 | 1 | 1 |
atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 16.4816 | 1 | 1 |
Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 27.1622 | 2 | 3 |
cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 17.9008 | 2 | 2 |
Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 17.5594 | 2 | 2 |
Chain A, Cruzipain | Trypanosoma cruzi | Potency | 21.4865 | 2 | 2 |
Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 8.9125 | 1 | 1 |
Chain A, HADH2 protein | Homo sapiens (human) | Potency | 0.1995 | 1 | 1 |
Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 32.9838 | 1 | 2 |
Chain B, HADH2 protein | Homo sapiens (human) | Potency | 0.1995 | 1 | 1 |
chromobox protein homolog 1 | Homo sapiens (human) | Potency | 53.7248 | 2 | 3 |
cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 7.5093 | 1 | 3 |
cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 1.1038 | 1 | 3 |
cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 13.5093 | 2 | 5 |
D(1A) dopamine receptor | Homo sapiens (human) | Potency | 0.5106 | 2 | 2 |
D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 16.4816 | 1 | 1 |
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 42.9517 | 2 | 2 |
endonuclease IV | Escherichia coli | Potency | 31.6228 | 1 | 1 |
enteropeptidase precursor | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 21.1401 | 3 | 3 |
euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 21.8434 | 1 | 5 |
EWS/FLI fusion protein | Homo sapiens (human) | Potency | 15.5016 | 4 | 12 |
flap endonuclease 1 | Homo sapiens (human) | Potency | 84.2790 | 1 | 2 |
Fumarate hydratase | Homo sapiens (human) | Potency | 11.7704 | 1 | 1 |
GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 13.8993 | 1 | 3 |
geminin | Homo sapiens (human) | Potency | 16.4115 | 4 | 6 |
glp-1 receptor, partial | Homo sapiens (human) | Potency | 18.5482 | 1 | 2 |
GLS protein | Homo sapiens (human) | Potency | 22.8741 | 2 | 2 |
glucocerebrosidase | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
glucokinase regulatory protein | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 14.1254 | 1 | 2 |
Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 34.3005 | 1 | 2 |
hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 12.5893 | 1 | 2 |
histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
IDH1 | Homo sapiens (human) | Potency | 5.1735 | 1 | 1 |
Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 1.4125 | 1 | 1 |
Integrin alpha-IIb | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
Integrin beta-3 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
Interferon beta | Homo sapiens (human) | Potency | 18.6800 | 1 | 6 |
isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 23.4648 | 3 | 3 |
lamin isoform A-delta10 | Homo sapiens (human) | Potency | 12.6450 | 2 | 3 |
lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 17.5594 | 1 | 2 |
M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 36.5836 | 1 | 2 |
Microtubule-associated protein tau | Homo sapiens (human) | Potency | 30.0499 | 1 | 3 |
mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 25.1189 | 2 | 2 |
muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 2 | 2 |
neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
NFKB1 protein, partial | Homo sapiens (human) | Potency | 11.2202 | 2 | 2 |
nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 15.8489 | 1 | 1 |
NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 58.0479 | 1 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 7.1912 | 2 | 2 |
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 18.1056 | 1 | 1 |
peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 37.9330 | 1 | 1 |
phosphopantetheinyl transferase | Bacillus subtilis | Potency | 34.1133 | 1 | 3 |
plasminogen precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
polyprotein | Zika virus | Potency | 11.7704 | 1 | 1 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
PPM1D protein | Homo sapiens (human) | Potency | 18.6800 | 1 | 4 |
Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
ras-related protein Rab-9A | Homo sapiens (human) | Potency | 79.0240 | 1 | 2 |
regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 22.7835 | 1 | 2 |
serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 18.4493 | 4 | 6 |
Smad3 | Homo sapiens (human) | Potency | 21.0880 | 1 | 3 |
survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
TDP1 protein | Homo sapiens (human) | Potency | 7.4428 | 2 | 10 |
thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 27.5708 | 1 | 3 |
Thrombopoietin | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 14.4334 | 4 | 4 |
urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
USP1 protein, partial | Homo sapiens (human) | Potency | 51.5206 | 2 | 5 |
vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 71.6999 | 1 | 3 |
WRN | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
10 kDa chaperonin | Escherichia coli | IC50 | 175.0000 | 2 | 2 |
10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 175.0000 | 2 | 2 |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Homo sapiens (human) | Ki | 0.0080 | 1 | 1 |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 1.6390 | 1 | 1 |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.4680 | 1 | 1 |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 3.2780 | 1 | 1 |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.7170 | 1 | 1 |
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 3.2780 | 1 | 1 |
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.7170 | 1 | 1 |
60 kDa chaperonin | Escherichia coli | IC50 | 175.0000 | 2 | 2 |
60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 175.0000 | 2 | 2 |
Acrosin | Sus scrofa (pig) | Ki | 2.3000 | 1 | 1 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 2.2140 | 1 | 1 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 2.1960 | 1 | 1 |
alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.3750 | 1 | 1 |
Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.5160 | 1 | 1 |
Amiloride-sensitive amine oxidase [copper-containing] | Homo sapiens (human) | Ki | 0.2900 | 1 | 1 |
Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 0.7930 | 1 | 1 |
Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 10.9738 | 1 | 2 |
Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 8.9905 | 1 | 2 |
Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 56.3500 | 2 | 2 |
ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 8.1333 | 3 | 3 |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 6.5000 | 1 | 1 |
Aurora kinase B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
bcl-2-related protein A1 | Mus musculus (house mouse) | IC50 | 6.2300 | 1 | 1 |
Beta-glucuronidase | Rattus norvegicus (Norway rat) | IC50 | 7.8000 | 1 | 1 |
Bile salt export pump | Homo sapiens (human) | IC50 | 257.6000 | 4 | 5 |
C-8 sterol isomerase | Saccharomyces cerevisiae S288C | Ki | 0.5000 | 1 | 1 |
Calcium-dependent protein kinase 4 | Plasmodium falciparum 3D7 | Ki | 150.0000 | 1 | 1 |
Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 7.1400 | 1 | 1 |
caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 7.1400 | 1 | 1 |
Coagulation factor X | Homo sapiens (human) | IC50 | 10.4000 | 1 | 1 |
Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 75.0000 | 3 | 3 |
Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 75.0000 | 3 | 3 |
Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 75.0000 | 3 | 3 |
Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 19.8667 | 3 | 3 |
Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 75.0000 | 3 | 3 |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0160 | 1 | 1 |
D(3) dopamine receptor | Homo sapiens (human) | IC50 | 3.9980 | 1 | 1 |
D(3) dopamine receptor | Homo sapiens (human) | Ki | 1.3580 | 1 | 1 |
Diamine acetyltransferase 1 | Homo sapiens (human) | Ki | 2.0000 | 1 | 1 |
DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
Emopamil-binding protein-like | Homo sapiens (human) | Ki | 0.0039 | 1 | 1 |
Genome polyprotein | IC50 | 0.7000 | 1 | 1 | |
Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 14.6000 | 1 | 1 |
Lysozyme C-1 | Rattus norvegicus (Norway rat) | IC50 | 9.0000 | 1 | 1 |
Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 1.7033 | 3 | 3 |
Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 6.5500 | 2 | 2 |
Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 1.4250 | 1 | 1 |
Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.5070 | 1 | 1 |
Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 1.5800 | 1 | 1 |
Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.2200 | 1 | 1 |
Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 2.8850 | 1 | 1 |
Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 2.0730 | 1 | 1 |
NADPH oxidase 1 | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 10.9738 | 1 | 2 |
Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 8.9905 | 1 | 2 |
Plasminogen | Homo sapiens (human) | IC50 | 28.4000 | 3 | 5 |
Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | IC50 | 1.4000 | 1 | 1 |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 13.8895 | 4 | 5 |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 8.9905 | 1 | 2 |
Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 81.0000 | 2 | 2 |
Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 582.0000 | 1 | 1 |
Protein kinase C alpha type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C beta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C delta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C eta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C gamma type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C theta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein kinase C zeta type | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
Protein S100-B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
Protein tyrosine phosphatase type IVA 1 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
Protein tyrosine phosphatase type IVA 2 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
Protein tyrosine phosphatase type IVA 3 | Homo sapiens (human) | IC50 | 35.8333 | 3 | 3 |
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 22.7500 | 1 | 2 |
Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.0150 | 1 | 1 |
Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 3.1590 | 1 | 1 |
Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 2.5100 | 1 | 1 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 2.2140 | 1 | 1 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 2.1960 | 1 | 1 |
Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 22.1000 | 1 | 1 |
Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 9.5000 | 1 | 1 |
SUMO-1 | Homo sapiens (human) | IC50 | 36.2450 | 2 | 2 |
Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 1.1600 | 1 | 1 |
Transcriptional activator protein LuxR | Aliivibrio fischeri | IC50 | 7.0000 | 1 | 1 |
Trypanothione reductase | Trypanosoma cruzi | IC50 | 72.0000 | 1 | 1 |
Trypanothione reductase | Trypanosoma cruzi | Ki | 23.0000 | 1 | 1 |
Trypsin-1 | Homo sapiens (human) | IC50 | 43.3333 | 1 | 3 |
Ubiquitin carboxyl-terminal hydrolase 1 | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 8.2315 | 2 | 2 |
Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 43.3333 | 1 | 3 |
WD repeat-containing protein 48 | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Kd | 0.0010 | 1 | 1 |
5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Kd | 0.0010 | 1 | 1 |
5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Kd | 0.0010 | 1 | 1 |
5-hydroxytryptamine receptor 5A | Homo sapiens (human) | EC50 | 92.4890 | 1 | 1 |
Albumin | Rattus norvegicus (Norway rat) | Kd | 14.0000 | 1 | 1 |
Calmodulin | Bos taurus (cattle) | Kd | 3.4000 | 1 | 1 |
Calmodulin-1 | Homo sapiens (human) | Kd | 1.0000 | 1 | 1 |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Kd | 0.0005 | 1 | 1 |
delta-type opioid receptor | Homo sapiens (human) | EC50 | 47.9575 | 2 | 2 |
insulin-degrading enzyme isoform 1 | Homo sapiens (human) | EC50 | 28.3680 | 2 | 2 |
mu-type opioid receptor isoform MOR-1 | Homo sapiens (human) | EC50 | 47.9575 | 2 | 2 |
Protein S100-B | Homo sapiens (human) | Kd | 1.0000 | 1 | 1 |
Protein S100-B | Rattus norvegicus (Norway rat) | Kd | 47.0000 | 2 | 2 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
---|---|---|---|---|---|
DNA repair protein RAD52 homolog isoform a | Homo sapiens (human) | AC50 | 13.0000 | 1 | 1 |
heat shock protein 90, putative | Plasmodium falciparum 3D7 | AC50 | 5.4700 | 1 | 1 |
heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | AC50 | 7.0650 | 1 | 1 |
Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | INH | 8.3000 | 1 | 1 |
Snq2p | Saccharomyces cerevisiae EC1118 | INH | 6.9000 | 1 | 1 |