A drug used to treat or prevent bacterial infections.
| Member | Definition | Class |
|---|
| 7432 s | A third-generation cephalosporin antibiotic with a [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino substituent at the 7 position of the cephem skeleton. An orally-administered agent, ceftibuten is used as the dihydrate to treat urinary-tract and respiratory-tract infections. | ceftibuten |
| a 195773 | A macrolide antibiotic which displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. The US Food and Drug Administration (FDA) have also granted orphan drug designation to cethromycin for the treatment of anthrax prophylaxis, tularemia, and plague (PDB entry: 1NWX). | cethromycin |
| acetylspiramycin | A macrolide antibiotic produced by various Streptomyces species. | spiramycin II |
| alpha bitter acid | An optically active cyclic ketone consisting of 3,5,6-trihydroxycyclohexa-2,4-dien-1-one bearing two 3-methylbut-2-en-1-yl substituents at positions 4 and 6 as well as a 3-methylbutanoyl group at the 2-position. | humulone |
| amdinocillin | A penicillin in which the 6beta substituent is [(azepan-1-yl)methylidene]amino; an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. | mecillinam |
| amdinocillin pivoxil | A penicillanic acid ester that is the [(2,2-dimethylpropanoyl)oxy]methyl ester and prodrug of mecillinam. | pivmecillinam |
| amikacin | An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group. | amikacin |
| amoxicillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group. | amoxicillin |
| ampicillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group. | ampicillin |
| apramycin | An aminoglycoside that is 2-deoxystreptamine that is substituted on the oxygen at position 4 by an (8R)-2-amino-8-O-(4-amino-4-deoxy-alpha-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl) group. | apramycin |
| arbekacin | A kanamycin that is kanamycin B bearing an N-(2S)-4-amino-2-hydroxybutyryl group on the aminocyclitol ring. | arbekacin |
| avibactam | A member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. | avibactam |
| azlocillin | A semisynthetic penicillin having a 6beta-{(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl}amino side-group. It is an antibiotic used in treating infections caused by Pseudomonas aeruginosa, Escherichia coli and Haemophilus influenzae. | azlocillin |
| aztreonam | A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. | aztreonam |
| benzoylmetronidazole | A benzoate ester resulting from the formal condensation of benzoic acid with the hydroxy group of metronidazole. | metronidazole benzoate |
| benzyl isothiocyanate | | benzyl isothiocyanate |
| brodimoprim | An aminopyrimidine that is 2,4-diaminopyrimidine in which the hydrogen at position 5 has been replaced by a 4-bromo-3,5-dimethoxybenzyl group. | brodimoprim |
| carbenicillin | A penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain. | carbenicillin |
| carumonam | An N-sulfonated monobactam antibiotic. | carumonam |
| cefaclor anhydrous | A cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. | cefaclor |
| cefadroxil anhydrous | A cephalosporin bearing methyl and (2R)-2-amino-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. | cefadroxil |
| cefaloram | A cephalosporin derivative with potent antibacterial activity which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division, inactivation of which interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in the weakening of the bacterial cell wall and causing cell lysis. | cefaloram |
| cefamandole | A cephalosporin compound having (R)-mandelamido and N-methylthiotetrazole side-groups. | cefamandole |
| cefamandole nafate | A cephalosporin prodrug having (R)-O-formylmandelamido and N-methylthiotetrazole side-groups. | cefamandole nafate |
| cefamandole nafate | An organic sodium salt that is the sodium salt of cefamandole. | cefamandole sodium |
| cefatrizine | A cephalosporin compound having (1H-1,2,3-triazol-4-ylsulfanyl)methyl and [(2R)-2-amino-2-(4-hydroxyphenyl)]acetamido side-groups. An antibacterial drug first prepared in the 1970s, it has more recently been found to be an inhibitor of eukaryotic elongation factor-2 kinase (eEF2K), which is known to regulate apoptosis, autophagy and ER stress in many types of human cancers. | cefatrizine |
| cefazedone | A first-generation cephalosporin antibiotic having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and [(3,5-dichloro-4-oxopyridin-1(4H)-yl)acetamido side-groups located at positions 3 and 7 respectively. | cefazedone |
| cefazolin | A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively. | cefazolin |
| cefdinir | A cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups. | cefdinir |
| cefditoren | A broad spectrum, third-generation cephalosporin antibiotic with (Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. Generally administered as its orally absorbed pivaloyloxymethyl ester prodrug, it is used for the treatment of mild to moderate infections caused by susceptible strains of microorganisms in acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections. | cefditoren |
| cefditoren pivoxil | The pivaloyloxymethyl ester prodrug of cefditoren. | cefditoren pivoxil |
| cefepime | A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. | cefepime |
| cefiderocol | A fourth-generation siderophore cephalosporin antibiotic having {1-[2-(2-chloro-3,4-dihydroxybenzamido)ethyl]pyrrolidinium-1-yl}methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino side groups located at positions 3 and 7 respectively, developed to combat a variety of bacterial pathogens, including beta-lactam- and carbapenem-resistant organisms. | cefiderocol |
| cefixime | A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. | cefixime |
| cefmenoxime | A third-generation cephalosporin antibiotic, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position and a [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl group at the 3-position. | cefmenoxime |
| cefmetazole | A second-generation cephalosporin antibiotic having N(1)-methyltetrazol-5-ylthiomethyl, {[(cyanomethyl)sulfanyl]acetyl}amino and methoxy side-groups at positions 3, 7beta and 7alpha respectively of the parent cephem bicyclic structure. | cefmetazole |
| cefodizime | A cephalosporin compound having 5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. | cefodizime |
| cefonicid | A cephalosporin bearing {[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and (R)-2-hydroxy-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. | cefonicid |
| cefoperazone | A semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance. | cefoperazone |
| ceforanide | A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many coliforms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species. | ceforanide |
| cefotaxime | A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups. | cefotaxime |
| cefotiam | A cephalosporin with ({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}sulfanyl)methyl and (2-amino-1,3-thiazol-4-yl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. A third generation beta-lactam cephalosporin antibiotic, it is active against a broad spectrum of both Gram positive and Gram negative bacteria. | cefotiam |
| cefoxitin | A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase. | cefoxitin |
| cefpiramide | A third-generation cephalosporin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and (R)-2-{[(4-hydroxy-6-methylpyridin-3-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It has a broad spectrum of antibacterial activity. | cefpiramide |
| cefpodoxime | A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis. | cefpodoxime |
| cefpodoxime proxetil | The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pharyngitis, and sinusitis. | cefpodoxime proxetil |
| cefprozil | A semisynthetic, second-generation cephalosporin, with prop-1-enyl and (R)-2-amino-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used to treat bronchitis as well as ear, skin and other bacterial infections. | cefprozil |
| cefsulodin | A pyridinium-substituted semi-synthetic, broad-spectrum, cephalosporin antibiotic. | cefsulodin |
| ceftazidime | A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. | ceftazidime |
| ceftizoxime | A parenteral third-generation cephalosporin, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position. | ceftizoxime |
| ceftriaxone | A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups. | ceftriaxone |
| cefuzonam | A second generation cephalosporin antibiotic. | cefuzonam |
| cephalexin | A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract. | cephalexin |
| cephaloridine | A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C. | cefaloridine |
| cephalothin | A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections. | cefalotin |
| cephapirin | A cephalosporin with acetoxymethyl and 2(pyridin-4-ylsulfanyl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. It is used (as its sodium salt) as an antibiotic, being effective against gram-negative and gram-positive organisms. | cephapirin |
| cephapirin sodium | The sodium salt of cephapirin. A first-generation cephalosporin antibiotic, it is effective against gram-negative and gram-positive organisms. Being more resistant to beta-lactamases than penicillins, it is effective agains most staphylococci, though not methicillin-resistant staphylococci. | cephapirin sodium |
| cephradine | A first-generation cephalosporin antibiotic with a methyl substituent at position 3, and a (2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetamido substituent at position 7, of the cephem skeleton. | cephradine |
| chloramphenicol | An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. | chloramphenicol |
| chlorphenesin | Glycerol in which the hydrogen of one of the primary hydroxy groups is substituted by a 4-chlorophenyl group. It has antifungal and antibacterial properties, and is used for treatment of cutaneous and vaginal infections. Its 1-carbamate is used as a skeletal muscle relaxant for the treatment of painful muscle spasm. | chlorphenesin |
| chlorquinaldol | A monohydroxyquinoline that is quinolin-8-ol which is substituted by a methyl group at position 2 and by chlorine at positions 5 and 7. An antifungal and antibacterial, it was formerly used for topical treatment of skin conditions and vaginal infections. | chlorquinaldol |
| cinoxacin | A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections. | cinoxacin |
| ciprofloxacin | A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. | ciprofloxacin zwitterion; ciprofloxacin |
| ciprofloxacin hydrochloride anhydrous | The anhydrous form of the monohydrochloride salt of ciprofloxacin. | ciprofloxacin hydrochloride (anhydrous) |
| clarithromycin | The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis. | clarithromycin |
| clavulanate potassium | A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases. | potassium clavulanate |
| clavulanic acid | Antibiotic isolated from Streptomyces clavuligerus. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. | clavulanic acid |
| cloxacillin | A semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6. | cloxacillin |
| cyclacillin | | cyclacillin |
| dalbavancin | A semisynthetic glycopeptide used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. | dalbavancin |
| demycarosylturimycin h | A macrolide antibiotic produced by various Streptomyces species that is used to treat toxoplasmosis and various other infections of soft tissues. | spiramycin I |
| dicloxacillin | A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group. | dicloxacillin |
| difloxacin | A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usually as the monohydrochloride salt) for the treatment of bacterial infections in dogs. | difloxacin |
| enoxacin | A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea. | enoxacin |
| ertapenem | Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. | ertapenem |
| finafloxacin | A quinolone that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted at positions 1, 6, 7 and 8 by cyclopropyl, fluoro, hexahydropyrrolo[3,4-b][1,4]oxazin-6-yl and cyano groups respectively; an antibiotic used for treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. | finafloxacin |
| fleroxacin | A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria. | fleroxacin |
| flomoxef | A second-generation oxacephem antibiotic in which the oxazine ring is substituted at C-3 with a hydroxyethyl-substituted tetrazolylthiomethyl group and the azetidinone ring carries 7alpha-methoxy and 7beta-{2-[(difluoromethyl)thiomethyl]acetamido} substituents. | flomoxef |
| floxacillin | A penicillin compound having a 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido] side-chain. | flucloxacillin |
| flurithromycin | An erythromycin derivative that is erythromycin A in which the hydrogen attached to the carbon at position 8 (alpha to the ketone carbonyl group) has been replaced by a fluorine. It has been used (generally as the corresponding monoethyl succinate ester) as an antibacterial drug. | flurithromycin |
| framycetin | A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. | framycetin |
| fumagillin | A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. | fumagillin |
| furazolidone | A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. | furazolidone |
| gamithromycin | A macrolide antibiotic with formula C40H76N2O12. It is used for the treatment of of bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle. The compound is also licensed in Europe for the treatment of footrot in sheep caused by Dichelobacter nodosus and Fusobacterium nodosus. | gamithromycin |
| garenoxacin | A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by a cyclopropyl group at position 1, an oxo group at position 4, a (1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl group at position 7, and a difluoromethoxy group at position 8. | garenoxacin |
| gemifloxacin | A 1,4-dihydro-1,8-naphthyridine with a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a substituted pyrrolin-1-yl group at the 7-position. | gemifloxacin |
| hetacillin | | hetacillin |
| imipenem, anhydrous | A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup. | imipenem zwitterion; imipenem |
| josamycin | A macrolide antibiotic produced by certain strains of Streptomyces narbonensis var. josamyceticus. | josamycin |
| kanamycin sulfate | | kanamycin A sulfate |
| l 749345 | The monosodium salt of ertapenem. It is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. It is more stable to renal dehydropeptidase I tham imipenem, and so unlike imipenem, its use with cilastatin, which inhibits the enzyme, is not required. | ertapenem sodium |
| levofloxacin | An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase. | levofloxacin |
| linezolid | An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex. | linezolid |
| ljc 10627 | A carbapenem antibiotic in which the azetidine and pyrroline rings carry 1-hydroxymethyl and pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio substituents respectively. | biapenem |
| ly 163892 | A synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. | loracarbef zwitterion; loracarbef |
| ly-146032 | A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue. | daptomycin |
| meropenem | A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. | meropenem |
| methenamine | A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms. | hexamethylenetetramine |
| methicillin | A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group. | methicillin |
| metronidazole | A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death. | metronidazole |
| mezlocillin | A penicillin in which the substituent at position 6 of the penam ring is a (2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido group. | mezlocillin |
| moxalactam | A broad-spectrum oxacephem antibiotic in which the oxazine ring is substituted with a tetrazolylthiomethyl group and the azetidinone ring carries methoxy and 2-carboxy-2-(4-hydroxyphenyl)acetamido substituents. | moxalactam |
| moxifloxacin | A quinolone that consists of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid bearing a cyclopropyl substituent at position 1, a fluoro substitiuent at position 6, a (4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl group at position 7 and a methoxy substituent at position 8. A member of the fluoroquinolone class of antibacterial agents. | moxifloxacin |
| moxifloxacin hydrochloride | A hydrochloride comprising equimolar amounts of moxifloxacin and hydrogen chloride. | moxifloxacin hydrochloride |
| mupirocin | An alpha,beta-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections. | mupirocin |
| nadifloxacin | | nadifloxacin |
| nafcillin | A penicillin in which the substituent at position 6 of the penam ring is a (2-ethoxy-1-naphthoyl)amino group. | nafcillin |
| nalidixic acid | A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species. | nalidixic acid |
| nifurtoinol | An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group and at position 3 by a hydroxymethyl group. | nifurtoinol |
| nitrofurantoin | An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA. | nitrofurantoin |
| nitrofurazone | A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections. | nitrofurazone |
| norfloxacin | A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. | norfloxacin |
| nxl 104 | An organic sodium salt that is the monosodium salt of avibactam. Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. | avibactam sodium |
| opt 80 | An 18-membered macrolide that is a fermentation product obtained from the Actinomycete Dactylosporangium aurantiacum. A narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections. | fidaxomicin |
| oritavancin | A semisynthetic glycopeptide used (as its bisphosphate salt) for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. | oritavancin |
| ornidazole | A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections. | ornidazole |
| oxacillin | A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta. | oxacillin |
| oxolinic acid | A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. | oxolinic acid |
| paromomycin | An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. | paromomycin |
| pefloxacin | A quinolone that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6 and 7 by ethyl, carboxy, fluorine, and 4-methylpiperazin-1-yl groups, respectively. | pefloxacin |
| pefloxacin mesylate | | pefloxacin mesylate |
| penamecillin | A penicillanic acid ester that is the acetoxymethyl ester of benzylpenicillin. It is a prodrug for benzylpenicillin. | penamecillin |
| penicillin g | A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. | benzylpenicillin |
| pipemidic acid | A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections. | pipemidic acid |
| piperacillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group. | piperacillin |
| piromidic acid | A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, substituted at position 2 by a pyrrolidin-1-yl group and at position 8 by an ethyl group. A synthetic antibacterial which is used for the treatment of urinary tract and intestinal infections. | piromidic acid |
| ppi-0903 | A cephalosporin having [4-(1-methylpyridinium-4-yl)-1,3-thiazol-2-yl]sulfanyl and {(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl}amino side groups located at positions 3 and 7 respectively. The N-phospho prodrug of ceftaroline, a broad-spectrum antibiotic active against methicillin-resistant Staphylococcus aureus (MRSA). It is used for the treatment of adults with acute bacterial skin and skin structure infections. | ceftaroline fosamil |
| quinacillin | A semisynthetic penicillase-resistant penicillin with antibacterial activity; it binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. | quinacillin |
| ribostamycin | An amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attached at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus). | ribostamycin |
| ristocetin | A heterodetic cyclic peptide that is produced by species of Amycolatopsis and Nocardia. | ristocetin |
| rosoxacin | A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by an ethyl group at position 1 and by a pyridin-4-yl group at position 7. An antibacterial drug, active against Neisseria gonorrhoeae, it has been used for treating urinary tract infections and certain sexually transmitted diseases. | rosoxacin |
| roxarsone | An organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl. | roxarsone |
| roxithromycin | Semisynthetic derivative of erythromycin A. | roxithromycin |
| ru 29246 | A cephalosporin compound having methoxymethyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(hydroxyimino)acetyl]amino side-groups; a third-generation cephalosporin antibiotic. | cefdaloxime |
| s 1006 | A cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. | cefcapene |
| salicylhydroxamic acid | A hydroxamic acid that is N-hydroxybenzamide carrying a phenolic hydroxy group at position 2. | salicylhydroxamic acid |
| silver sulfadiazine | | silver(1+) sulfadiazinate |
| sirolimus | A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent. | sirolimus |
| spectinomycin | A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis. | spectinomycin |
| spectinomycin dihydrochloride | A hydrochloride obtained by combining spectinomycin with two molar equivalents of hydrochloric acid. An antibiotic that is active against gram-negative bacteria and used (as its pentahydrate) to treat gonorrhea. | spectinomycin dihydrochloride |
| streptogramin a | A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus. | pristinamycin IIA |
| streptogramin b | A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus. | pristinamycin IA |
| streptomycin | A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class | streptomycin |
| sulfabenzamide | A sulfonamide containing a benzamido substituent on nitrogen. An antibacterial/antimicrobial, it is often used in conjunction with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation. | sulfabenzamide |
| sulfacetamide | A sulfonamide that is sulfanilamide acylated on the sulfonamide nitrogen. | sulfacetamide |
| sulfachlorpyridazine | A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. | sulfachloropyridazine |
| sulfadoxine | A sulfonamide consisting of pyrimidine having methoxy substituents at the 5- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. In combination with the antiprotozoal pyrimethamine (CHEBI:8673) it is used as an antimalarial. | sulfadoxine |
| sulfamethazine | A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamethazine |
| sulfaperine | A substituted aniline that is sulfanilamide in which on of the hydrogens of the sulfonamide group has been replaced by a 5-methylpyrimidin-2-yl group. | sulfaperin |
| sulfaphenazole | A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent. | sulfaphenazole |
| sulfathiourea | A substituted aniline that is thiourea in which one of the hydrogens has been replaced by a (p-aminophenyl)sulfonyl group. | sulfathiourea |
| sulfisoxazole | A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. | sulfisoxazole |
| telavancin | A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria. | telavancin |
| thiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. | thiram |
| tiamulin | A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae. | tiamulin |
| ticarcillin | A penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group. | ticarcillin |
| tilmicosin | A macrolide antibiotic with formula C46H80N2O13. It is used for the treatment of respiratory disease in cattle at high risk of developing bovine respiratory disease associated with Mannheimia haemolytica. | tilmicosin |
| tinidazole | 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent. | tinidazole |
| trimethoprim | An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge. | trimethoprim |
| vancomycin | A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. | vancomycin |
| virginiamycin factor s1 | A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. | virginiamycin S1 |
| zithromax | A macrolide antibiotic useful for the treatment of bacterial infections. | azithromycin |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 20.5860 | 1 | 13 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.1259 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 14.4136 | 2 | 6 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 52.0183 | 4 | 11 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 55.5694 | 1 | 3 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 13.0232 | 2 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 17.6020 | 1 | 22 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.1009 | 1 | 3 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 14.6014 | 1 | 12 |
| AR protein | Homo sapiens (human) | Potency | 15.0001 | 12 | 99 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 30.6308 | 2 | 10 |
| arylsulfatase A | Homo sapiens (human) | Potency | 7.5545 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 24.2074 | 3 | 5 |
| Ataxin-2 | Homo sapiens (human) | Potency | 22.6205 | 1 | 8 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 18.4602 | 5 | 10 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 22.4564 | 2 | 13 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 0.1425 | 2 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 69.8095 | 1 | 6 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 0.7943 | 1 | 3 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 76.8806 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 0.7943 | 1 | 3 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 76.8806 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 28.0243 | 2 | 22 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 23.2039 | 1 | 23 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 15.5864 | 2 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 22.0919 | 2 | 10 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 28.3708 | 1 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 39.1512 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 17.4969 | 2 | 8 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 64.2779 | 1 | 12 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 17.0508 | 3 | 20 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 18.0838 | 3 | 13 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 18.0206 | 2 | 13 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 17.4969 | 2 | 8 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 67.8096 | 2 | 14 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 22.4069 | 1 | 4 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 13.7394 | 1 | 5 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 25.8039 | 1 | 8 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 24.6173 | 1 | 7 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 18.3916 | 2 | 22 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 19.6762 | 2 | 16 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 22.6429 | 1 | 13 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 20.2407 | 1 | 5 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 32.0919 | 2 | 14 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 41.7335 | 2 | 20 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 42.9257 | 2 | 12 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 0.0231 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 10.3754 | 2 | 4 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.9599 | 11 | 108 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 14.1690 | 3 | 12 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 17.7335 | 6 | 67 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 11.4954 | 1 | 28 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 14.4592 | 4 | 16 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 19.3814 | 3 | 14 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 50.3148 | 1 | 3 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 63.0957 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 17.4895 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 25.8039 | 1 | 8 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| GALC protein | Homo sapiens (human) | Potency | 0.6887 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 19.0423 | 1 | 12 |
| geminin | Homo sapiens (human) | Potency | 7.9411 | 2 | 36 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 18.3877 | 3 | 29 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 18.0105 | 1 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 16.7698 | 2 | 14 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 13.7859 | 4 | 26 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 23.8770 | 1 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 21.4397 | 2 | 8 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 23.8770 | 1 | 2 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 23.8770 | 1 | 2 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 2.3134 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 40.9903 | 1 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 20.1393 | 2 | 10 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 13.7394 | 1 | 15 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 20.8351 | 1 | 11 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 6.0448 | 2 | 5 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 19.5260 | 2 | 8 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 25.8039 | 1 | 8 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 2.2740 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 23.8570 | 1 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 11.0878 | 2 | 9 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 3.9811 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 12.5247 | 1 | 5 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 55.3430 | 2 | 6 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 25.8039 | 1 | 16 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 22.4254 | 3 | 12 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 8 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 5.0202 | 1 | 23 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 11.1944 | 1 | 5 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 23.3075 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 12.1020 | 3 | 7 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 9.9237 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 17.7256 | 2 | 16 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 12.3609 | 2 | 5 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 4.7219 | 1 | 3 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 20.8784 | 1 | 9 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 4.0580 | 3 | 6 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 3.6654 | 2 | 4 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 4.3105 | 1 | 5 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 29.0241 | 4 | 32 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 4.3727 | 1 | 7 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 25.4592 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 9.9049 | 2 | 14 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 12.2888 | 1 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 19.7277 | 3 | 19 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 38.4025 | 1 | 3 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 34.9120 | 2 | 7 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 10.2465 | 2 | 10 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 28.4166 | 5 | 20 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 15.4946 | 5 | 18 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 13.2394 | 2 | 5 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 42.9660 | 3 | 13 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 2.7889 | 1 | 5 |
| polyprotein | Zika virus | Potency | 17.4895 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 19.9843 | 1 | 8 |
| PPM1D protein | Homo sapiens (human) | Potency | 20.8212 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 37.2340 | 3 | 16 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 79.4328 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 11.6964 | 2 | 11 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 14.1254 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 18.0606 | 2 | 31 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 33.2792 | 3 | 30 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 20.2105 | 4 | 27 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 18.1689 | 1 | 5 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 16.8735 | 2 | 8 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 16.8735 | 2 | 8 |
| Smad3 | Homo sapiens (human) | Potency | 12.2781 | 1 | 4 |
| snurportin-1 | Homo sapiens (human) | Potency | 55.3430 | 2 | 6 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 19.6124 | 2 | 16 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 10.9583 | 1 | 6 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 19.4260 | 1 | 9 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.9206 | 2 | 78 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 42.7481 | 1 | 4 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 40.7284 | 4 | 16 |
| Thrombopoietin | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 19.8286 | 3 | 37 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 26.4804 | 2 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 19.2113 | 6 | 38 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 35.6291 | 1 | 2 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 2.7889 | 1 | 5 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 2.7889 | 1 | 5 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 53.4180 | 2 | 10 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 17.6984 | 2 | 11 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 15.8382 | 5 | 11 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 52.2454 | 1 | 13 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 20.6273 | 1 | 6 |
| Vpr | Human immunodeficiency virus 1 | Potency | 34.8384 | 1 | 4 |
| WRN | Homo sapiens (human) | Potency | 26.0770 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 90.3000 | 6 | 10 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 3 |
| 14 kDa phosphohistidine phosphatase | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| 30S ribosomal protein S1 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 15.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 86.8167 | 3 | 3 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 56.8000 | 1 | 2 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | IC50 | 287.7541 | 7 | 8 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 90.3000 | 6 | 10 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 3 |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 0.3200 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.0501 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5629 | 2 | 2 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5629 | 2 | 2 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5629 | 2 | 2 |
| Alternative oxidase, mitochondrial | Trypanosoma brucei brucei | IC50 | 5.9300 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 46.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 33.9750 | 4 | 4 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 9.5500 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 17.0000 | 1 | 2 |
| AmpC | Escherichia coli | IC50 | 0.0600 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 29 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 30.5188 | 8 | 8 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 221.0600 | 4 | 5 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 500.0075 | 2 | 2 |
| Beta-lactamase | Pseudomonas aeruginosa PAO1 | IC50 | 33.6427 | 2 | 3 |
| Beta-lactamase | Staphylococcus aureus | IC50 | 0.0800 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | Ki | 7.7000 | 1 | 1 |
| Beta-lactamase | Mycobacterium tuberculosis CDC1551 | Ki | 6.3000 | 1 | 1 |
| Beta-lactamase | Acinetobacter baumannii | IC50 | 1,850.0000 | 2 | 2 |
| Beta-lactamase | Acinetobacter pittii | IC50 | 1,208.6733 | 3 | 3 |
| Beta-lactamase | Citrobacter gillenii | IC50 | 0.0090 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 100.0000 | 1 | 1 |
| Beta-lactamase | Escherichia coli | IC50 | 84.7895 | 4 | 6 |
| Beta-lactamase | Klebsiella pneumoniae | IC50 | 0.4375 | 3 | 4 |
| Beta-lactamase | Pseudomonas aeruginosa | IC50 | 0.1125 | 3 | 4 |
| Beta-lactamase | Pseudomonas luteola | IC50 | 0.0360 | 1 | 1 |
| Beta-lactamase | Salmonella enterica subsp. enterica serovar Westhampton | IC50 | 0.0100 | 1 | 1 |
| Beta-lactamase | Serratia fonticola | IC50 | 72.8000 | 1 | 1 |
| Beta-lactamase | Shouchella clausii | IC50 | 0.0850 | 1 | 1 |
| Beta-lactamase | Acinetobacter baumannii | Ki | 1.1867 | 3 | 7 |
| Beta-lactamase | Citrobacter freundii | Ki | 0.6000 | 1 | 4 |
| Beta-lactamase | Escherichia coli | Ki | 0.0110 | 1 | 1 |
| Beta-lactamase OXA-1 | Escherichia coli | IC50 | 3.2000 | 1 | 1 |
| Beta-lactamase SHV-1 | Escherichia coli | IC50 | 0.0280 | 1 | 1 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | IC50 | 0.1700 | 2 | 2 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | Ki | 2.0000 | 1 | 1 |
| Beta-lactamase TEM | Escherichia coli | IC50 | 7.7136 | 6 | 6 |
| Beta-lactamase TEM | Escherichia coli | Ki | 11.2667 | 1 | 3 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Cryptosporidium parvum | IC50 | 14.0000 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Leishmania major | IC50 | 20.5000 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium berghei ANKA | IC50 | 0.1200 | 5 | 5 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | IC50 | 68.2550 | 2 | 2 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | IC50 | 79.1654 | 46 | 60 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Leishmania major | Ki | 0.1200 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | Ki | 1.8558 | 7 | 7 |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | IC50 | 89.3200 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 418.5626 | 5 | 73 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 739.6125 | 1 | 8 |
| BlaVIM-1 | Escherichia coli | Ki | 40.0000 | 1 | 1 |
| Botulinum neurotoxin type A | Clostridium botulinum | IC50 | 10.1000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 1.9000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 127.7321 | 1 | 28 |
| Canalicular multispecific organic anion transporter 1 | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | IC50 | 10.5000 | 1 | 1 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | Ki | 11.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 53.0400 | 1 | 5 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 53.0400 | 1 | 5 |
| carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 | Homo sapiens (human) | IC50 | 4.8167 | 1 | 3 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 19.1000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.8160 | 1 | 1 |
| Chain A, Dihydrofolate reductase | Bacillus anthracis | IC50 | 77,200.0000 | 1 | 1 |
| Chain A, Dihydrofolate reductase | Homo sapiens (human) | Ki | 0.6050 | 1 | 4 |
| Chain A, dihydrofolate reductase (DHFR) | Bacillus anthracis | IC50 | 77,200.0000 | 1 | 1 |
| Chain A, Isoleucyl-tRNA synthetase | Thermus thermophilus | Ki | 0.2500 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 434.5000 | 2 | 2 |
| Class D beta-lactamase | Brachyspira pilosicoli | IC50 | 2.0000 | 1 | 1 |
| corticotropin releasing factor-binding protein | Homo sapiens (human) | IC50 | 47.1000 | 1 | 1 |
| corticotropin-releasing hormone receptor 2 | Homo sapiens (human) | IC50 | 47.1000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 30.0000 | 3 | 3 |
| Cytochrome P450 2B1 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Cytochrome P450 2C18 | Homo sapiens (human) | IC50 | 60.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 184.6667 | 3 | 3 |
| Cytochrome P450 2C19 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 130.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 17.1533 | 35 | 40 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 0.3500 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 30.0000 | 3 | 3 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 35.9920 | 1 | 5 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 21.2517 | 11 | 11 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 8.0450 | 2 | 2 |
| D-alanyl-D-alanine dipeptidase | Enterococcus faecium | Ki | 62.0000 | 1 | 1 |
| D-amino-acid oxidase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Dihydrofolate reductase | Candida albicans | IC50 | 24.5144 | 5 | 5 |
| Dihydrofolate reductase | Escherichia coli K-12 | IC50 | 259.5702 | 32 | 46 |
| Dihydrofolate reductase | Gallus gallus (chicken) | IC50 | 493.3333 | 3 | 3 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 202.3339 | 45 | 63 |
| Dihydrofolate reductase | Lacticaseibacillus casei | IC50 | 0.3492 | 4 | 4 |
| Dihydrofolate reductase | Lactococcus lactis subsp. lactis Il1403 | IC50 | 0.4500 | 1 | 1 |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | IC50 | 88.0000 | 1 | 1 |
| Dihydrofolate reductase | Neisseria gonorrhoeae | IC50 | 0.4500 | 2 | 2 |
| Dihydrofolate reductase | Pneumocystis carinii | IC50 | 262.5412 | 40 | 53 |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | IC50 | 3,206.1735 | 48 | 59 |
| Dihydrofolate reductase | Saccharomyces cerevisiae S288C | IC50 | 12.0000 | 1 | 1 |
| Dihydrofolate reductase | Staphylococcus aureus | IC50 | 982.6437 | 10 | 17 |
| Dihydrofolate reductase | Streptococcus pneumoniae TIGR4 | IC50 | 64.1815 | 2 | 6 |
| Dihydrofolate reductase | Escherichia coli K-12 | Ki | 0.0016 | 8 | 9 |
| Dihydrofolate reductase | Gallus gallus (chicken) | Ki | 79.4221 | 2 | 3 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 11.6282 | 12 | 12 |
| Dihydrofolate reductase | Lacticaseibacillus casei | Ki | 0.0652 | 2 | 3 |
| Dihydrofolate reductase | Mus musculus (house mouse) | Ki | 0.5000 | 1 | 1 |
| Dihydrofolate reductase | Pneumocystis carinii | Ki | 93.4345 | 3 | 3 |
| Dihydrofolate reductase | Staphylococcus aureus | Ki | 0.2115 | 13 | 13 |
| Dihydrofolate reductase | Bacillus anthracis | IC50 | 45.7880 | 5 | 5 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 3,165.7850 | 2 | 2 |
| Dihydrofolate reductase | Mycobacterium avium | IC50 | 33.5633 | 9 | 9 |
| Dihydrofolate reductase | Pneumocystis jirovecii | IC50 | 0.0920 | 1 | 1 |
| Dihydrofolate reductase | Bacillus anthracis | Ki | 12.7600 | 3 | 3 |
| Dihydrofolate reductase | Salmonella enterica subsp. enterica serovar Typhi | Ki | 0.0075 | 1 | 2 |
| Dihydrofolate reductase type 1 | Escherichia coli | IC50 | 0.2500 | 2 | 2 |
| Dihydrofolate reductase type 1 from Tn4003 | Staphylococcus aureus | IC50 | 109.5308 | 1 | 4 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 2.7000 | 3 | 3 |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | IC50 | 2.7000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 1 isoform b | Homo sapiens (human) | IC50 | 7.2800 | 1 | 1 |
| DNA gyrase subunit A | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 77.6500 | 1 | 2 |
| DNA gyrase subunit A | Escherichia coli K-12 | IC50 | 15.1122 | 28 | 35 |
| DNA gyrase subunit A | Mycobacterium tuberculosis H37Rv | IC50 | 277.1155 | 16 | 21 |
| DNA gyrase subunit A | Staphylococcus aureus | IC50 | 94.1324 | 21 | 33 |
| DNA gyrase subunit B | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 77.6500 | 1 | 2 |
| DNA gyrase subunit B | Escherichia coli K-12 | IC50 | 13.1776 | 23 | 30 |
| DNA gyrase subunit B | Mycobacterium tuberculosis H37Rv | IC50 | 361.3018 | 12 | 14 |
| DNA gyrase subunit B | Mycolicibacterium smegmatis | IC50 | 50.0000 | 3 | 3 |
| DNA gyrase subunit B | Staphylococcus aureus | IC50 | 39.2472 | 17 | 25 |
| DNA primase | Mycobacterium tuberculosis CDC1551 | IC50 | 75.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 169.8667 | 3 | 3 |
| DNA topoisomerase 4 subunit A | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 545.8500 | 1 | 2 |
| DNA topoisomerase 4 subunit A | Escherichia coli K-12 | IC50 | 51.0000 | 1 | 1 |
| DNA topoisomerase 4 subunit A | Staphylococcus aureus | IC50 | 4.4007 | 10 | 14 |
| DNA topoisomerase 4 subunit B | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 545.8500 | 1 | 2 |
| DNA topoisomerase 4 subunit B | Staphylococcus aureus | IC50 | 6.4850 | 6 | 6 |
| Dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Dual specificity protein phosphatase CDC14A | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Mus musculus (house mouse) | IC50 | 20.0000 | 1 | 1 |
| Efflux transporter | Salmonella enterica subsp. enterica serovar Newport | IC50 | 0.0050 | 1 | 2 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 7.8133 | 3 | 3 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | IC50 | 4.8900 | 2 | 2 |
| Endothelin-1 receptor | Homo sapiens (human) | Ki | 13.4650 | 1 | 1 |
| exodeoxyribonuclease V subunit RecB | Escherichia coli str. K-12 substr. MG1655 | IC50 | 32.0750 | 2 | 2 |
| exodeoxyribonuclease V subunit RecC | Escherichia coli str. K-12 substr. MG1655 | IC50 | 32.0750 | 2 | 2 |
| exodeoxyribonuclease V subunit RecD | Escherichia coli str. K-12 substr. MG1655 | IC50 | 64.0500 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 44.6684 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 1,600.0000 | 2 | 2 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.2900 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 28.3575 | 2 | 8 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 23.5400 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Glutathione peroxidase 1 | Homo sapiens (human) | Ki | 133.3667 | 1 | 3 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 22.9400 | 1 | 3 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.5500 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 100.0000 | 1 | 1 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 1.8255 | 2 | 2 |
| Isoleucine--tRNA ligase | Escherichia coli K-12 | Ki | 0.0025 | 1 | 1 |
| Janus kinase 2 (a protein tyrosine kinase) | Homo sapiens (human) | IC50 | 0.2230 | 1 | 1 |
| L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase | Mycobacterium tuberculosis H37Rv | IC50 | 5,000.0000 | 1 | 1 |
| Lactoperoxidase | Bos taurus (cattle) | IC50 | 1.2000 | 1 | 2 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 2 |
| Lecithin retinol acyltransferase | Homo sapiens (human) | IC50 | 14.9000 | 1 | 1 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 1.8255 | 2 | 2 |
| Lethal factor | Bacillus anthracis | Ki | 0.2535 | 2 | 2 |
| Lethal(3)malignant brain tumor-like protein 1 | Homo sapiens (human) | IC50 | 0.0980 | 1 | 1 |
| Low molecular weight phosphotyrosine protein phosphatase | Homo sapiens (human) | IC50 | 110.7500 | 2 | 2 |
| low molecular weight phosphotyrosine protein phosphatase isoform c | Homo sapiens (human) | IC50 | 19.6000 | 1 | 1 |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | IC50 | 0.1800 | 1 | 1 |
| M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 12.0800 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 0.6200 | 3 | 3 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 2.5450 | 2 | 2 |
| MecA | Staphylococcus aureus | IC50 | 710.0000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | IC50 | 2.7300 | 1 | 1 |
| Methionine aminopeptidase | Escherichia coli K-12 | IC50 | 100.0000 | 1 | 1 |
| Methionine aminopeptidase 1 | Saccharomyces cerevisiae S288C | IC50 | 100.0000 | 1 | 1 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 0.0082 | 4 | 4 |
| Microsomal glutathione S-transferase 1 | Homo sapiens (human) | Ki | 155.8300 | 1 | 3 |
| Monoglyceride lipase | Homo sapiens (human) | IC50 | 0.9772 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 2.8000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 258.9500 | 1 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 122.3448 | 1 | 29 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 14.0000 | 2 | 2 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| NH(3)-dependent NAD(+) synthetase | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 1.0000 | 1 | 1 |
| Penicillin-binding protein 1A | Pseudomonas aeruginosa PAO1 | IC50 | 3.3400 | 1 | 1 |
| Peptidoglycan D,D-transpeptidase MrdA | Escherichia coli K-12 | IC50 | 0.5900 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | IC50 | 0.0042 | 6 | 6 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | IC50 | 0.0010 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | Ki | 1.3505 | 4 | 4 |
| Peptidyl-prolyl cis-trans isomerase FKBP5 | Homo sapiens (human) | Ki | 0.0030 | 1 | 1 |
| Phospholipase C, beta 3 (phosphatidylinositol-specific) | Homo sapiens (human) | IC50 | 122.4810 | 1 | 1 |
| Phospholipase C, gamma 1 | Homo sapiens (human) | IC50 | 1.2120 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 9.6500 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 30.0998 | 2 | 2 |
| Potassium voltage-gated channel subfamily E member 1 | Homo sapiens (human) | IC50 | 278.2980 | 2 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 783.4389 | 21 | 37 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 125.0000 | 1 | 2 |
| Potassium voltage-gated channel subfamily KQT member 1 | Homo sapiens (human) | IC50 | 278.2980 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 8.1900 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 | 6,433.3333 | 1 | 3 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | Ki | 560.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 1.0400 | 1 | 1 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 53.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase alpha | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase beta | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase epsilon | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase F | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase gamma | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase mu | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | IC50 | 0.2250 | 2 | 2 |
| Renin | Callithrix jacchus (white-tufted-ear marmoset) | IC50 | 17.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 9.2000 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 8.3167 | 2 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 24.1500 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Ki | 249.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 249.0000 | 1 | 1 |
| Retinal dehydrogenase 1 | Homo sapiens (human) | IC50 | 0.0200 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 77.0000 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 0.9906 | 11 | 11 |
| Serine/threonine-protein kinase mTOR | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Serine/threonine-protein phosphatase 5 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Serum paraoxonase/arylesterase 1 | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 145.4998 | 2 | 2 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.0501 | 1 | 1 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | IC50 | 7,692.7273 | 6 | 11 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | Ki | 14,086.2464 | 7 | 56 |
| Solute carrier family 15 member 1 | Rattus norvegicus (Norway rat) | Ki | 10,621.6667 | 1 | 9 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | IC50 | 338.0000 | 1 | 2 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | IC50 | 6,600.0000 | 1 | 2 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | Ki | 5,485.6800 | 4 | 46 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 5,176.7286 | 3 | 35 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 53.7400 | 2 | 2 |
| Solute carrier family 22 member 11 | Homo sapiens (human) | Ki | 2.5771 | 1 | 7 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 535.0160 | 1 | 2 |
| Solute carrier family 22 member 5 | Homo sapiens (human) | IC50 | 965.0000 | 1 | 2 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 1,425.0000 | 1 | 2 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | IC50 | 1,186.5714 | 2 | 7 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Ki | 1.3600 | 1 | 8 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 527.4035 | 1 | 2 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 988.0000 | 3 | 11 |
| Solute carrier family 22 member 7 | Homo sapiens (human) | IC50 | 2,694.0000 | 1 | 5 |
| Solute carrier family 22 member 7 | Rattus norvegicus (Norway rat) | IC50 | 3,260.0000 | 1 | 5 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Mus musculus (house mouse) | IC50 | 75.1100 | 1 | 10 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | IC50 | 1,180.0000 | 2 | 6 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 12.4506 | 3 | 10 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | Ki | 538.1600 | 2 | 5 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 2.0952 | 2 | 2 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 3.3113 | 1 | 1 |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | Homo sapiens (human) | IC50 | 8.1900 | 1 | 1 |
| SUMO-1 | Homo sapiens (human) | IC50 | 35.2325 | 2 | 4 |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | IC50 | 0.2250 | 2 | 2 |
| Thioredoxin reductase | Entamoeba histolytica | Ki | 3.3000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 3 |
| Thymidylate synthase | Escherichia coli K-12 | IC50 | 115.6033 | 2 | 6 |
| Thymidylate synthase | Homo sapiens (human) | IC50 | 115.6033 | 2 | 6 |
| Thyroid peroxidase | Homo sapiens (human) | IC50 | 1.2000 | 1 | 2 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 0.0158 | 1 | 1 |
| Tubulin alpha-1A chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin alpha-1B chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin alpha-1C chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin alpha-3C chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin alpha-3E chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin alpha-4A chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-1 chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-2A chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-2B chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-3 chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-4A chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-4B chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-6 chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tubulin beta-8 chain | Homo sapiens (human) | IC50 | 11.2700 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 190.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | IC50 | 16.8000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | Ki | 6.6000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 22 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 6 | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 7 | Homo sapiens (human) | IC50 | 250.0000 | 1 | 1 |
| tyrosine-protein phosphatase non-receptor type 7 isoform 2 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 9 | Homo sapiens (human) | IC50 | 350.0000 | 1 | 1 |
| Tyrosyl-DNA phosphodiesterase 1 | Homo sapiens (human) | IC50 | 14,500.0000 | 2 | 2 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 6 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 6 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 6 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 6 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 6 |
| V-type proton ATPase subunit B, brain isoform | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 168.9000 | 1 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 304.6384 | 8 | 8 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 238.7699 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 367.2200 | 5 | 5 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 367.2200 | 5 | 5 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 367.2200 | 5 | 5 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 30S ribosomal protein S1 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | Kd | 0.0363 | 1 | 1 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 12.0000 | 1 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Kd | 0.5300 | 1 | 1 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 82.0000 | 1 | 1 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | EC50 | 69.6933 | 2 | 3 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Beta-lactamase | Klebsiella pneumoniae | Kd | 0.8500 | 1 | 1 |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | Kd | 12.0000 | 1 | 1 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chain A, Dihydrofolate Reductase | Staphylococcus aureus | Kd | 0.4300 | 1 | 1 |
| Chain A, Mutant Al2 6e7p9g | Mus musculus (house mouse) | Kd | 1.5400 | 1 | 1 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| corticotropin releasing factor-binding protein | Homo sapiens (human) | EC50 | 53.0000 | 1 | 1 |
| corticotropin-releasing hormone receptor 2 | Homo sapiens (human) | EC50 | 53.0000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase Mdm2 isoform a | Homo sapiens (human) | EC50 | 0.2200 | 3 | 3 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Estrogen receptor | Rattus norvegicus (Norway rat) | EC50 | 91.2842 | 1 | 10 |
| Estrogen receptor beta | Rattus norvegicus (Norway rat) | EC50 | 91.2842 | 1 | 10 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Eukaryotic translation initiation factor 4E | Homo sapiens (human) | Kd | 0.0005 | 1 | 1 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | Kd | 47.0000 | 2 | 2 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| heat shock protein 90 | Candida albicans | EC50 | 150.0000 | 1 | 1 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| LAP4 | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 5.3850 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Kd | 2.9000 | 1 | 1 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Menin | Homo sapiens (human) | Kd | 15.6000 | 1 | 1 |
| Metallo-beta-lactamase type 2 | Klebsiella pneumoniae | Kd | 11.0000 | 1 | 1 |
| Methionine--tRNA ligase, mitochondrial | Homo sapiens (human) | EC50 | 7.9000 | 1 | 1 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Multidrug resistance protein MdtK | Escherichia coli K-12 | Kd | 94.6500 | 1 | 2 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | Kd | 2.0000 | 1 | 1 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 4.6967 | 2 | 3 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | EC50 | 0.0364 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | Homo sapiens (human) | Kd | 0.0002 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| POsterior Segregation | Caenorhabditis elegans | EC50 | 49.7940 | 1 | 1 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Programmed cell death protein 4 | Homo sapiens (human) | EC50 | 0.0500 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein Rev | HIV-1 M:B_HXB2R | Kd | 0.1800 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RISC-loading complex subunit TARBP2 | Homo sapiens (human) | Kd | 6.3270 | 2 | 2 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RPL19A | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 14.7400 | 1 | 1 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 0.0006 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 33.2570 | 1 | 1 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 25.3624 | 2 | 19 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | EC50 | 0.4000 | 1 | 1 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Trace amine-associated receptor 5 | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 13.0921 | 6 | 6 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 223.0000 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Zinc finger protein mex-5 | Caenorhabditis elegans | EC50 | 33.2570 | 1 | 1 |