| Member | Definition | Role |
|---|
| (1-methylsulfonyl-4-piperidinyl)-(4-morpholinyl)methanone | | (1-methylsulfonyl-4-piperidinyl)-(4-morpholinyl)methanone |
| 1-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-N-(phenylmethyl)-3-piperidinecarboxamide | | 1-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-N-(phenylmethyl)-3-piperidinecarboxamide |
| 1-(4,6-dimethoxy-1,3,5-triazin-2-yl)-N-(thiophen-2-ylmethyl)-4-piperidinecarboxamide | | 1-(4,6-dimethoxy-1,3,5-triazin-2-yl)-N-(thiophen-2-ylmethyl)-4-piperidinecarboxamide |
| 1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-(5-methyl-2-pyridinyl)-4-piperidinecarboxamide | | 1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-(5-methyl-2-pyridinyl)-4-piperidinecarboxamide |
| 1-[4-(4-bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide | | 1-[4-(4-bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide |
| 1-[4-cyano-2-(2-furanyl)-5-oxazolyl]-4-piperidinecarboxamide | | 1-[4-cyano-2-(2-furanyl)-5-oxazolyl]-4-piperidinecarboxamide |
| 2-[2-[[[1-(1H-imidazol-5-ylsulfonyl)-3-piperidinyl]-oxomethyl]amino]-4-thiazolyl]acetic acid ethyl ester | | 2-[2-[[[1-(1H-imidazol-5-ylsulfonyl)-3-piperidinyl]-oxomethyl]amino]-4-thiazolyl]acetic acid ethyl ester |
| 2-oxopiperidine-3-carbohydrazide | | 2-oxopiperidine-3-carbohydrazide |
| bms 387032 | A secondary carboxamide resulting from the formal condensation of the carboxy group of piperidine-4-carboxylic acid with the amino group of 5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-amine. It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases and exhibits anti-cancer properties. | N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide |
| bupivacaine | A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline. | 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide |
| l 779976 | A member of the class of indoles that is (betaS)-beta-methyl-D-tryptophan in which the primary amino group undergoes formal condensation with the carboxy group of 4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylic acid and the carboxy group undegoes formal condensation with the amino group of (1R,3S)-cyclohexane-1,3-diyldimethanamine. It is a selective nonpeptidic agonist of the somatostatin subtype-2 (SST2) receptor with Ki of 0.05 nM. | L-779976 |
| ly2090314 | A member of the class of diazepinoindoles that is 1,2,3,4-tetrahydro[1,4]diazepino[6,7,1-hi]indole substituted by piperidin-1-ylcarbonyl, 4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl and fluoro groups at position 2, 7 and 9, respectively. It is a potent ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3alpha and GSK-3beta. The drug is in clinical development for the treatment of advanced/metastatic cancer. | LY-2090314 |
| mepivacaine | A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic. | mepivacaine |
| mepivacaine hydrochloride | The hydrochloride salt of mepivacaine. It is used as a local anaesthetic. | mepivacaine hydrochloride |
| n-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide | A piperidinecarboxamide that is TEMPO carrying an 2-iodoacetamido group at position 4. | 4-(2-iodacetamido)-TEMPO |
| N-(4-methylcyclohexyl)-1-(2-pyrazinyl)-4-piperidinecarboxamide | | N-(4-methylcyclohexyl)-1-(2-pyrazinyl)-4-piperidinecarboxamide |
| N-[(3-methoxyphenyl)methyl]-1-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)sulfonyl]-3-piperidinecarboxamide | | N-[(3-methoxyphenyl)methyl]-1-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)sulfonyl]-3-piperidinecarboxamide |
| N-[2-(3,4-diethoxyphenyl)ethyl]-1-[6-(4-morpholinyl)-3-pyridazinyl]-4-piperidinecarboxamide | | N-[2-(3,4-diethoxyphenyl)ethyl]-1-[6-(4-morpholinyl)-3-pyridazinyl]-4-piperidinecarboxamide |
| N-[3-(1-azepanyl)propyl]-1-ethylsulfonyl-4-piperidinecarboxamide | | N-[3-(1-azepanyl)propyl]-1-ethylsulfonyl-4-piperidinecarboxamide |
| N-[4-(4-methylphenyl)-2-thiazolyl]-1-thiophen-2-ylsulfonyl-4-piperidinecarboxamide | | N-[4-(4-methylphenyl)-2-thiazolyl]-1-thiophen-2-ylsulfonyl-4-piperidinecarboxamide |
| nipecotic acid amide | The amide resulting from the formal condensation of nipecotic acid with ammonia. | nipecotamide |
| pha 793887 | | N-[6,6-dimethyl-5-[(1-methyl-4-piperidinyl)-oxomethyl]-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide |
| piperidine-4-carboxamide | | 4-Piperidine carboxamide |
| ropivacaine | A piperidinecarboxamide-based amide-type local anaesthetic (amide caine) in which (S)-N-propylpipecolic acid and 2,6-dimethylaniline are combined to form the amide bond. | (S)-ropivacaine |
| tempace | A piperidinecarboxamide that is TEMPO carrying an acetamido group at position 4. | 4-acetamido-TEMPO |