Hemoglobinopathies

A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.

Synonym
Hemoglobinopathies

Excerpt	Reference
"Since most hemoglobinopathies are inherited as autosomal recessive conditions, screening, counseling, and prenatal diagnosis are important components of prenatal care for these women."	( , 1996)
"Hemoglobinopathies are important inherited disorders with considerable high prevalence in Asia."	( Wiwanitkit, V, 2006)
"The hemoglobinopathies are a heterogeneous group of single-gene disorders that includes the structural hemoglobin variants and the thalassemias."	( , 2007)
"Hemoglobinopathies are common in Thailand."	( Khoprasert, S; Khositseth, S; Opastirakul, S; Peuksungnern, R; Sirikanerat, A; Thongnoppakhun, W; Viprakasit, V; Wattanasirichaigoon, D; Wongbenjarat, K; Yenchitsomanus, PT, 2007)
"Hemoglobinopathies are an uncommon cause of cyanosis and low oxygen saturation on pulse oximetry."	( Clingenpeel, J; Mounts, J; Villella, A; White, N, 2010)
"Thalassemias and hemoglobinopathies are highly prevalent in Thailand and other Southeast Asian countries."	( Duangruang, S; Rithapirom, S; Sangkitporn, S; Sangkitporn, SK; Suwannakan, B; Tanjatham, S; Yodtup, C; Yowang, A, 2011)
"Hemoglobin (Hb) D hemoglobinopathies are widespread diseases in northwestern India and usually present with mild hemolytic anemia and mild to moderate splenomegaly."	( Mishra, RM; Pandey, S; Saxena, R; Shah, V, 2012)
"Hemoglobinopathies are a group of inherited single-gene disorders found commonly in the Mediterranean region, Middle East, Indian subcontinent, Burma, and South East Asia."	( Achoubi, N; Asghar, M; Murry, B; Saraswathy, KN, 2012)
"Hemoglobinopathies are the most common inherited diseases in southern China."	( Chen, HZ; Huang, FT; Huang, Y; Li, GC; Lin, CP; Lin, F; Lin, M; Liu, GR; Lu, M; Wang, JL; Wang, Q; Wang, Y; Wen, YF; Weng, QQ; Wu, DH; Wu, JR; Xie, LX; Yang, H; Yang, HT; Yang, LY; Yao, MQ; Zeng, JB; Zeng, RX; Zhan, XF; Zheng, L; Zhu, JJ, 2013)
"Hemoglobinopathies are genetic disorders of globin chains characterized by the decreased expression of α- or β-globin chains (thalassemias) or by the synthesis of an abnormal protein (hemoglobin variants in, e."	( Cotton, F; Gulbis, B; Wolff, F, 2013)
"Hemoglobinopathies are among the most studied and frequent pathologies."	( Calvopiña, D; Domínguez, Y; Mora, M; Villacís, J; Zurita, C, 2013)
"Hemoglobinopathies are the most common inherited disorders in humans and are thus the target of screening programs worldwide."	( Chui, DH; Costello, CE; Dikler, S; Heckendorf, C; McComb, ME; Théberge, R, 2015)
"Most hemoglobinopathies are inherited disorders."	( Hattori, Y; Yamashiro, Y, 2015)
"The β-hemoglobinopathies are the most common monogenic disorders in humans, with symptoms arising after birth when the fetal γ-globin genes are silenced and the adult β-globin gene is activated."	( Dean, A; Krivega, I, 2016)
"Hemoglobinopathies are caused by point mutation in globin gene that results in structural variant of hemoglobin."	( Bhat, V; Das, R; Mandal, AK; Mathew, B; Mitra, G; Pal, D; Ross, C, 2016)
"Thalassemia and hemoglobinopathies are inherited red blood cell disorders found worldwide."	( Abdullah, NA; Bahar, R; Che Yaakob, CA; Ghazali, S; Hassan, R; Mohd Radzi, MA; Mohd Yusoff, S; Wan Mohd Saman, WA, 2016)
"Gene therapy for hemoglobinopathies is currently based on transplantation of autologous hematopoietic stem cells genetically modified with a lentiviral vector expressing a globin gene under the control of globin transcriptional regulatory elements."	( Cavazzana, M; Ferrari, G; Mavilio, F, 2017)
"Gene therapy for hemoglobinopathies is currently based on transplantation of autologous hematopoietic stem cells genetically modified with an integrating lentiviral vector expressing a globin gene under the control of globin transcriptional regulatory elements."	( Ferrari, G; Lidonnici, MR, 2018)
"Hemoglobinopathies are a group of inherited single gene disorders."	( Acharjee, S; Colah, RB; Das, RS; Ghosh, K; Mukherjee, MB; Ray, J; Upadhye, D, 2018)
"Hemoglobinopathies are monogenic disorders with autosomal recessive inheritance."	( Marques-Garcia, F, 2022)
"Hemoglobinopathies are major public health problems worldwide."	( Chaibunruang, A; Changtrakul, D; Fucharoen, G; Fucharoen, S; Pansuwan, A; Sanchaisuriya, K; Yamsri, S, 2022)
"Hemoglobinopathies are genetic disorders that affect the hemoglobin (Hb) molecule."	( Aguirre, F; Ávalos, V; Díaz, L; Eandi Eberle, S; Harris, V; Pepe, C; Rossetti, E, 2023)
"Hemoglobinopathies are one of the most widespread hereditary disorders in Turkey."	( Ayan, D; Balci, T; Bayraktar, M; Gunturk, I; Seydel, GS, 2023)

Excerpt	Reference
"Both diagnosis and treatment of hemoglobinopathies have been associated with an increased risk of fertility impairment."	( Balcerek, M; Borgmann-Staudt, A; Diepold, M; Diesch-Furlanetto, T; Drexler, B; Dülberg, J; Eisenreich, B; Friedrich, LA; Hegemann, I; Infanti, L; Kager, L; Kroiss, S; Mandic, L; Merki, R; Njue, LM; Radauer-Plank, AC; Roll, S; Rovó, A; Salow, V; Scheinemann, K; Schilling, R; Schneider, M; Sommerhäuser, G, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	657 (56.06)	23.3326
1990's	140 (11.95)	12.5806
2000's	116 (9.90)	18.1394
2010's	194 (16.55)	28.8240
2020's	65 (5.55)	9.53

Drug	Relationship Strength	Studies	Trials
chloroacetaldehyde	low	1	0
2,3-diphosphoglycerate	low	7	0
acetaldehyde	low	1	0
acetone	low	1	0
adenine	low	3	0
ammonium hydroxide	low	2	0
1-butanol	low	1	0
butyric acid	low	5	0
carbamates	low	1	0
carbon monoxide	low	6	0
chlorine	low	2	0
methylmalonic acid	low	1	0
aminocaproic acid	low	1	0
formaldehyde	low	1	0
glycine	low	14	0
glyceraldehyde	low	1	0
glycerol	low	3	0
hydrogen carbonate	low	4	0
histamine	low	2	0
phytic acid	low	1	0
oxalic acid	low	1	0
phenylacetic acid	low	1	0
1-propanol	low	2	0
propionic acid	low	2	0
pyridoxal	low	1	0
sulfites	low	7	0
uric acid	low	4	0
urea	low	7	0
mercaptoethanol	low	1	0
phenytoin	low	1	0
acetaminophen	medium	1	1
acetazolamide	low	1	0
theophylline	medium	1	1
aspirin	low	3	0
benserazide	low	1	0
chloroquine	low	2	0
chlorothiazide	low	1	0
chlorpromazine	low	1	0
cilostazol	low	1	0
cystamine	low	1	0
dapsone	low	2	0
deferiprone	medium	3	1
deferoxamine	medium	12	1
diethyl pyrocarbonate	low	1	0
dilazep	medium	2	1
valproic acid	low	3	0
erythrosine	low	4	0
furosemide	low	1	0
glutethimide	low	1	0
hydroxyurea	low	32	0
indomethacin	low	1	0
isoniazid	low	1	0
2-propanol	low	4	0
meperidine	low	1	0
entinostat	low	1	0
pentoxifylline	low	1	0
phenacetin	low	3	0
phenazopyridine	low	1	0
phenobarbital	low	2	0
phenoxybenzamine	low	1	0
4-phenylbutyric acid	low	2	0
potassium chloride	low	3	0
promazine	low	2	0
propranolol	low	1	0
pyrimethamine	low	2	0
thalidomide	low	1	0
prednisolone	low	1	0
estriol	low	3	0
penicillamine	low	1	0
prednisone	low	1	0
penicillin g	low	1	0
isoflurophate	low	2	0
alanine	low	17	0
serine	low	6	0
chloramphenicol	low	3	0
aspartic acid	low	6	0
glutamine	low	8	0
lysine	low	5	0
sucrose	low	1	0
2,3,4,6-tetrachlorophenol	low	1	0
galactose	low	1	0
edetic acid	low	5	0
tyrosine	low	9	0
methylene blue	low	4	0
leucine	low	21	0
methionine	low	4	0
phenylalanine	low	4	0
tubercidin	low	1	0
ampicillin	low	2	0
cytarabine	low	1	0
asparagine	low	2	0
histidine	low	9	0
valine	low	11	0
tryptophan	low	3	0
isoleucine	low	1	0
arginine	low	5	0
tromethamine	low	1	0
n-pentanoic acid	low	1	0
pyrroles	low	4	0
framycetin	low	1	0
dodecyl sulfate	low	1	0
quinazolines	low	1	0
thiazoles	medium	1	1
azacitidine	low	7	0
xanthinol niacinate	medium	1	1
alpha-aminopyridine	low	1	0
cyanogen bromide	low	3	0
medroxyprogesterone	low	1	0
malondialdehyde	medium	4	1
3,5-dichlorophenol	low	1	0
2,2-dimethylbutyric acid	low	2	0
2,6-dichloroindophenol	low	2	0
sodium hydroxide	low	1	0
thorium dioxide	low	1	0
d-alpha tocopherol	medium	4	1
propanidid	low	1	0
2-tert-butylhydroquinone	low	1	0
sulfadoxine	low	1	0
fluorescein-5-isothiocyanate	low	2	0
streptomycin	low	1	0
fructosamine	low	10	0
vidarabine	medium	3	1
technetium	low	2	0
argon	medium	1	1
gadolinium	medium	1	1
gold	low	2	0
uranium	low	1	0
ferrous sulfate	medium	1	1
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	1	0
copper sulfate	low	1	0
fluorine	low	1	0
trolamine salicylate	low	2	0
urobilinogen	low	2	0
osmium tetroxide	low	1	0
phosphotyrosine	low	1	0
phenyl acetate	low	6	0
transferrin	medium	10	1
azides	low	1	0
eterobarb	low	1	0
ribavirin	low	2	0
simvastatin	low	1	0
adenosine	low	1	0
vanadates	low	1	0
fanasil, pyrimethamine drug combination	low	1	0
4-nitrobenzylthioinosine	low	1	0
triazoles	medium	4	1
isobutyramide	medium	2	1
artemisinin	low	1	0
nsc-172755	low	2	0
fibrinogen	low	1	0
homocysteine	low	1	0
3-aminobenzeneboronic acid	low	1	0
cyanates	low	2	0
proline	low	7	0
dirhodium tetraacetate	low	1	0
calcium pyrophosphate	low	1	0
angiotensin ii	low	2	0
deferasirox	medium	5	2
cortisone	low	1	0
oxytocin	low	1	0
ouabain	low	1	0
puromycin	low	1	0
retinol	low	2	0
tacrolimus	low	1	0
decitabine	low	4	0
melphalan	low	1	0
riboflavin	low	1	0
glycosides	low	2	0
isomethyleugenol	low	3	0
flavin-adenine dinucleotide	low	3	0
pyrophosphate	low	1	0
fludarabine	medium	3	1
chlorprothixene	low	1	0
thioinosine	low	1	0
phenylthiourea	low	1	0
thiourea	low	1	0
sodium propionate	low	1	0
D-fructopyranose	low	1	0
nadp	low	3	0
ace-011	low	1	0
freedom	low	1	0
sodium dodecyl sulfate	low	1	0
zinc protoporphyrin ix	low	1	0
alpha-chymotrypsin	low	1	0
bilirubin	low	16	0
vitamin k semiquinone radical	low	1	0
cucurbitacin c	low	1	0
misoprostol	low	1	0
thromboxane b2	low	1	0
morphine	low	1	0
deamino arginine vasopressin	low	1	0
ergothioneine	low	1	0
lead	low	4	0
diamide	low	1	0
barium	low	1	0
aluminum	low	1	0
sulfur	low	1	0
phosphorus	low	1	0
salubrinal	low	1	0
oxalates	low	1	0
beta-escin	low	4	0
epsilon-(gamma-glutamyl)-lysine	low	1	0
ticagrelor	low	1	0
rivaroxaban	low	1	0
losartan potassium	medium	31	1
sepharose	low	1	0
pituitrin	low	1	0
acid phosphatase	low	4	0
nad	low	3	0
tin mesoporphyrin	low	1	0
oligonucleotides	low	8	0
cellulose	low	16	0
arginine butyrate	low	1	0
fibrinopeptide a	low	1	0
glycolipids	low	1	0
unc 0638	low	1	0
natriuretic peptide, brain	low	1	0
heme	low	31	0
ascorbic acid	low	1	0
tetracycline	low	1	0
salicylates	low	1	0
dicumarol	low	1	0
pyrethrins	low	1	0
rome	low	1	0
agar	low	8	0
vitamin b 12	low	5	0
cyclosporine	low	2	0
orabase	low	1	0
thromboplastin	low	2	0
exudates	low	14	0
guanine	low	2	0
hypoxanthine	low	1	0
folic acid	low	12	0
sildenafil citrate	low	4	0
eye	low	2	0
acetylcellulose	low	2	0
concanavalin a	low	1	0
phosphorus radioisotopes	low	4	0

Protein Targets (1,520)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	32	0	0	32
aldehyde dehydrogenase 1 family, member A1	37	0	0	37
glucocorticoid receptor [Homo sapiens]	47	0	0	47
farnesoid X nuclear receptor	27	0	0	27
estrogen nuclear receptor alpha	73	0	0	73
Voltage-dependent calcium channel gamma-2 subunit	27	0	0	27
Cellular tumor antigen p53	40	0	0	40
Glutamate receptor 2	27	0	0	27
Choline O-acetyltransferase	0	1	0	2
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
RAR-related orphan receptor gamma	45	0	0	45
GLI family zinc finger 3	46	0	0	46
AR protein	63	0	0	63
retinoic acid nuclear receptor alpha variant 1	53	0	0	53
retinoid X nuclear receptor alpha	35	0	0	35
peroxisome proliferator-activated receptor delta	27	0	0	27
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	32	0	0	32
activating transcription factor 6	17	0	0	17
v-jun sarcoma virus 17 oncogene homolog (avian)	23	0	0	23
Histone H2A.x	24	0	0	24
thyroid hormone receptor beta isoform a	17	0	0	17
heat shock protein beta-1	20	0	0	20
nuclear factor erythroid 2-related factor 2 isoform 1	51	0	0	51
lamin isoform A-delta10	40	0	0	40
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Luciferase	17	0	0	17
interleukin 8	11	0	0	11
acetylcholinesterase	14	0	0	14
15-lipoxygenase, partial	8	0	0	8
phosphopantetheinyl transferase	21	0	0	21
USP1 protein, partial	22	0	0	22
GLS protein	25	0	0	25
TDP1 protein	49	0	0	49
estrogen receptor 2 (ER beta)	21	0	0	21
nuclear receptor subfamily 1, group I, member 3	42	0	0	42
cytochrome P450 family 3 subfamily A polypeptide 4	37	0	0	37
estrogen-related nuclear receptor alpha	61	0	0	61
pregnane X nuclear receptor	36	0	0	36
G	23	0	0	23
cytochrome P450 2D6	17	0	0	17
peroxisome proliferator activated receptor gamma	34	0	0	34
vitamin D (1,25- dihydroxyvitamin D3) receptor	28	0	0	28
euchromatic histone-lysine N-methyltransferase 2	50	0	0	50
aryl hydrocarbon receptor	21	0	0	21
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	18	0	0	18
cytochrome P450 2C9 precursor	9	0	0	9
vitamin D3 receptor isoform VDRA	21	0	0	21
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
thyroid hormone receptor beta isoform 2	45	0	0	45
huntingtin isoform 2	3	0	0	3
nuclear receptor ROR-gamma isoform 1	14	0	0	14
geminin	51	0	0	51
peripheral myelin protein 22	23	0	0	23
lethal factor (plasmid)	17	0	0	17
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Interferon beta	31	0	0	31
HLA class I histocompatibility antigen, B alpha chain	23	0	0	23
Tyrosinase	0	4	0	4
Histamine H2 receptor	11	0	1	12
Nuclear receptor ROR-gamma	17	0	0	17
Nuclear factor erythroid 2-related factor 2	0	0	1	3
Inositol hexakisphosphate kinase 1	23	0	0	23
cytochrome P450 2C9, partial	23	0	0	23
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
chromobox protein homolog 1	28	0	0	28
Cytochrome P450 1A2	0	6	1	9
Cytochrome P450 3A4	0	11	1	13
Cytochrome P450 2C8	0	4	0	4
Cytochrome P450 2D6	0	6	1	7
Cytochrome P450 2C9	0	15	0	15
Cytochrome P450 2B6	0	2	0	2
Cytochrome P450 3A5	0	2	0	2
Cytochrome P450 2C19	0	6	0	6
Solute carrier family 22 member 6	0	3	0	4
Solute carrier family 22 member 8	0	4	0	5
thyroid stimulating hormone receptor	22	0	0	22
progesterone receptor	26	0	0	26
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	9	0	0	9
mitogen-activated protein kinase 1	12	0	0	12
Peroxisome proliferator-activated receptor alpha	2	0	0	2
ATPase family AAA domain-containing protein 5	18	0	0	18
Ataxin-2	25	0	0	25
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
DNA polymerase iota isoform a (long)	20	0	0	20
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase TEM	0	2	0	3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	1	0	1
Pentachlorophenol 4-monooxygenase	0	0	1	1
Chain A, Beta-lactamase	17	0	0	17
thioredoxin reductase	27	0	0	27
ATAD5 protein, partial	14	0	0	14
67.9K protein	15	0	0	15
Multidrug resistance-associated protein 4	0	33	0	34
Equilibrative nucleoside transporter 1	0	5	0	5
Solute carrier family 28 member 3	0	3	0	3
Adenosine kinase	0	1	0	3
ATP-dependent phosphofructokinase	18	0	0	18
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
survival motor neuron protein isoform d	15	0	0	15
Histone deacetylase 3	0	8	1	9
Histone deacetylase 4	0	7	1	8
Histone deacetylase 1	0	8	2	10
Histone deacetylase 7	0	7	1	8
Histone deacetylase 2	0	8	2	10
Polyamine deacetylase HDAC10	0	5	1	6
Histone deacetylase 11	0	5	1	6
Histone deacetylase 8	0	7	1	8
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Histone deacetylase 6	0	7	1	8
Histone deacetylase 9	0	7	1	8
Histone deacetylase 5	0	7	1	8
SMAD family member 2	15	0	0	15
SMAD family member 3	15	0	0	15
caspase 7, apoptosis-related cysteine protease	6	0	0	6
caspase-3	6	0	0	6
thyroid stimulating hormone receptor	18	0	0	18
thyrotropin-releasing hormone receptor	6	0	0	6
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
Microtubule-associated protein tau	16	0	0	16
Smad3	14	0	0	14
EWS/FLI fusion protein	28	0	0	28
cytochrome P450 3A4 isoform 1	18	0	0	18
Gamma-aminobutyric acid receptor subunit pi	18	3	1	22
ATP-binding cassette sub-family C member 3	0	31	0	31
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	4	1	14
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	10	0	10
Bile salt export pump	0	54	0	54
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	14	1	31
Carbonic anhydrase 2	0	16	2	35
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 3	0	4	1	13
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	18	3	1	22
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	18	3	1	22
Gamma-aminobutyric acid receptor subunit gamma-2	18	3	1	22
UDP-glucuronosyltransferase 1-6	0	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	18	3	1	22
Gamma-aminobutyric acid receptor subunit alpha-3	18	3	1	22
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Carbonic anhydrase 4	0	10	1	19
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	4	1	13
Gamma-aminobutyric acid receptor subunit gamma-1	18	3	1	22
Gamma-aminobutyric acid receptor subunit alpha-2	18	3	1	22
Gamma-aminobutyric acid receptor subunit alpha-4	18	3	1	22
Gamma-aminobutyric acid receptor subunit gamma-3	18	3	1	22
Gamma-aminobutyric acid receptor subunit alpha-6	18	3	1	22
Carbonic anhydrase 5A, mitochondrial	0	6	1	16
Prostaglandin G/H synthase 2	0	6	1	8
Carbonic anhydrase 7	0	4	1	13
Cytochrome P450 2J2	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	18	4	1	23
Gamma-aminobutyric acid receptor subunit beta-3	18	3	1	22
Gamma-aminobutyric acid receptor subunit beta-2	18	3	1	22
Carbonic anhydrase 9	0	7	2	19
GABA theta subunit	18	3	1	22
Canalicular multispecific organic anion transporter 1	0	29	0	29
Carbonic anhydrase 15	0	6	0	12
Carbonic anhydrase 13	0	4	0	11
Gamma-aminobutyric acid receptor subunit epsilon	18	3	1	22
Carbonic anhydrase 14	0	4	1	14
Carbonic anhydrase 5B, mitochondrial	0	4	1	14
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	20	0	0	20
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GALC protein	4	0	0	4
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	19	0	0	19
Carbonic anhydrase	0	1	0	1
Bloom syndrome protein isoform 1	14	0	0	14
muscleblind-like protein 1 isoform 1	4	0	0	4
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2A6	0	3	0	3
5-hydroxytryptamine receptor 2A	0	3	0	3
Androgen receptor	0	5	0	5
Translocator protein	0	1	1	2
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	6	1	12
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	2	0	3
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	5	1	12
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	3	0	4
Delta-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	1	7
Carbonic anhydrase	0	5	0	10
Kappa-type opioid receptor	0	3	1	5
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	6	1	0	7
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	1	0	7
D(2) dopamine receptor	0	5	0	6
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	1	5
Fatty-acid amide hydrolase 1	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	5	1	11
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	7
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	8
Carbonic anhydrase	0	2	0	9
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	7
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	7
Carbonic anhydrase 4	0	2	0	6
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	7	0	0	7
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	15	0	0	15
NPYLR7B	0	0	2	2
IDH1	14	0	0	14
glycogen synthase kinase-3 beta isoform 1	0	0	5	5
flap endonuclease 1	11	0	0	11
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	7	0	0	7
Purine nucleoside phosphorylase	0	3	0	3
Epidermal growth factor receptor	0	6	0	6
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	2	3
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	6	3	10
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	3
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	6	5	13
Adenosine receptor A2b	0	2	1	5
Adenosine receptor A2b	0	2	1	4
Adenylate kinase 2, mitochondrial	0	2	0	3
Adenosine receptor A1	0	6	4	13
Adenylate kinase isoenzyme 1	0	2	0	3
Phosphatidylinositol 4-kinase alpha	0	3	0	4
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	1	0	2
Adenosine deaminase	0	0	0	3
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	3	0	4
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Phosphatidylinositol 4-kinase type 2-alpha	0	3	0	4
Phosphatidylinositol 4-kinase beta	0	3	0	4
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	3	0	3
Alcohol dehydrogenase S chain	0	3	0	3
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	5	0	6
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
5'-nucleotidase	0	1	0	2
Choline O-acetyltransferase	0	1	0	1
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	2	1	3
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	4
Glutamate receptor ionotropic, NMDA 1	0	6	1	12
Proton-coupled amino acid transporter 1	0	7	0	8
Adenosine deaminase	0	0	0	1
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	1	1	4
Tyrosine-protein kinase	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
Chain A, Ferritin light chain	10	0	0	10
Chain A, Apolipoprotein	0	0	1	1
nonstructural protein 1	4	0	0	4
D(1A) dopamine receptor	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Plasminogen	0	2	1	3
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	7	0	0	7
Beta-lactamase	0	0	0	2
acid sphingomyelinase	2	0	0	2
apical membrane antigen 1, AMA1	6	0	0	6
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
DNA polymerase beta	5	0	0	5
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase kappa isoform 1	14	0	0	14
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	4	0	4
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	23	2	3	28
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	1	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	1	0	2
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	1	0	3
glucocerebrosidase	5	0	0	5
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	6	0	0	6
alpha-galactosidase	4	0	0	4
cytochrome P450 2C19 precursor	7	0	0	7
muscarinic acetylcholine receptor M1	12	0	0	12
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, inducible	0	1	0	2
Cationic amino acid transporter 3	0	2	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	10	0	0	10
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Polyphenol oxidase 2	0	4	0	5
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	4	0	5
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Alpha-2B adrenergic receptor	0	5	2	8
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	4	0	4
Neutral amino acid transporter B(0)	0	4	0	4
Carbonic anhydrase-like protein, putative	0	0	0	8
Amino acid transporter	0	4	0	4
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	10
Glutamate receptor ionotropic, NMDA 2C	0	4	1	10
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	4	1	10
Glutamate receptor ionotropic, NMDA 3B	0	4	1	10
Glutamate receptor ionotropic, NMDA 3A	0	4	1	10
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	5	0	0	5
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	3
Prostaglandin G/H synthase 2	0	2	0	3
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	5	1	0	6
Myeloperoxidase	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	5	1	0	6
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	8	1	9
Sigma non-opioid intracellular receptor 1	0	0	1	1
glp-1 receptor, partial	8	0	0	8
pregnane X receptor	7	0	0	7
Fumarate hydratase	12	0	0	12
PPM1D protein	7	0	0	7
Thrombopoietin	6	0	0	6
polyprotein	12	0	0	12
Parkin	4	0	0	4
peripheral myelin protein 22 isoform 1	13	0	0	13
hemoglobin subunit beta	2	0	0	2
cellular tumor antigen p53 isoform a	6	0	0	6
ras-related protein Rab-9A	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
urokinase-type plasminogen activator precursor	12	0	0	12
plasminogen precursor	12	0	0	12
urokinase plasminogen activator surface receptor precursor	12	0	0	12
DNA (cytosine-5)-methyltransferase 1	0	3	0	3
Multidrug and toxin extrusion protein 1	0	5	0	5
Histone-lysine N-methyltransferase EHMT2	0	4	1	6
M-phase phosphoprotein 8	8	0	0	8
Zinc finger protein mex-5	0	0	1	1
POsterior Segregation	0	0	2	2
Genome polyprotein	0	1	0	1
Replicase polyprotein 1ab	0	6	3	9
Hexokinase-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	10	0	0	10
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Solute carrier organic anion transporter family member 1B1	0	6	0	7
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Matrix metalloproteinase-9	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Chain A, Nitrile Hydratase alpha subunit	0	1	0	1
Chain B, Nitrile Hydratase beta subunit	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Free fatty acid receptor 3	0	0	2	2
Methyl-accepting chemotaxis protein NahY	0	0	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
Caspase-2	0	0	1	1
streptokinase A precursor	0	0	3	3
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	4	0	5
30S ribosomal protein S7	0	4	0	5
50S ribosomal protein L15	0	4	0	5
50S ribosomal protein L10	0	4	0	5
50S ribosomal protein L11	0	4	0	5
50S ribosomal protein L7/L12	0	4	0	5
50S ribosomal protein L19	0	4	0	5
50S ribosomal protein L1	0	4	0	5
50S ribosomal protein L20	0	4	0	5
50S ribosomal protein L27	0	4	0	5
50S ribosomal protein L28	0	4	0	5
50S ribosomal protein L29	0	4	0	5
50S ribosomal protein L31	0	4	0	5
50S ribosomal protein L31 type B	0	4	0	5
50S ribosomal protein L32	0	4	0	5
50S ribosomal protein L33	0	4	0	5
50S ribosomal protein L34	0	4	0	5
50S ribosomal protein L35	0	4	0	5
50S ribosomal protein L36	0	4	0	5
30S ribosomal protein S10	0	4	0	5
30S ribosomal protein S11	0	4	0	5
30S ribosomal protein S12	0	4	0	5
30S ribosomal protein S13	0	4	0	5
30S ribosomal protein S16	0	4	0	5
30S ribosomal protein S18	0	4	0	5
30S ribosomal protein S19	0	4	0	5
30S ribosomal protein S20	0	4	0	5
30S ribosomal protein S2	0	4	0	5
30S ribosomal protein S3	0	4	0	5
30S ribosomal protein S4	0	4	0	5
30S ribosomal protein S5	0	4	0	5
30S ribosomal protein S8	0	4	0	5
30S ribosomal protein S9	0	4	0	5
50S ribosomal protein L13	0	4	0	5
50S ribosomal protein L14	0	4	0	5
50S ribosomal protein L16	0	4	0	5
50S ribosomal protein L23	0	4	0	5
30S ribosomal protein S15	0	4	0	5
50S ribosomal protein L17	0	4	0	5
50S ribosomal protein L21	0	4	0	5
50S ribosomal protein L30	0	4	0	5
50S ribosomal protein L6	0	4	0	5
30S ribosomal protein S14	0	4	0	5
30S ribosomal protein S17	0	4	0	5
30S ribosomal protein S1	0	4	0	5
50S ribosomal protein L18	0	4	0	5
50S ribosomal protein L2	0	4	0	5
50S ribosomal protein L3	0	4	0	5
50S ribosomal protein L24	0	4	0	5
50S ribosomal protein L4	0	4	0	5
50S ribosomal protein L22	0	4	0	5
50S ribosomal protein L5	0	4	0	5
30S ribosomal protein S21	0	4	0	5
50S ribosomal protein L25	0	4	0	5
50S ribosomal protein L36 2	0	4	0	5
Methionine--tRNA ligase, mitochondrial	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	2	3	5
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	3	3
Amyloid-beta precursor protein	0	4	0	5
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	3	3	6
Muscarinic acetylcholine receptor M2	0	7	1	8
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	6	3	10
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Replicase polyprotein 1ab	0	3	3	6
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	6	1	7
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Alpha-2C adrenergic receptor	0	6	2	9
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	6	1	7
Serine/threonine-protein kinase mTOR	0	2	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	14	0	14
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	3	5
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
transcriptional regulator ERG isoform 3	3	0	0	3
ORF73	0	0	1	1
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	3
Adenylate cyclase type 1	0	2	0	2
cytochrome P450 2D6 isoform 1	5	0	0	5
histone deacetylase 9 isoform 3	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Proteasome subunit alpha type-7	0	0	0	1
Solute carrier family 22 member 1	0	8	0	9
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 4	0	6	0	6
Potassium channel subfamily K member 2	0	1	1	2
Albumin	0	2	4	6
Albumin	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	0	2
Aldo-keto reductase family 1 member B1	0	5	0	5
ATP-dependent translocase ABCB1	0	6	0	7
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M5	0	2	0	2
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Muscarinic acetylcholine receptor M2	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	6	1	8
Alpha-1B adrenergic receptor	0	6	1	7
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	4	0	4
D(3) dopamine receptor	0	7	0	7
5-hydroxytryptamine receptor 1A	0	8	1	10
Alpha-2B adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	2	0	2
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	6	1	8
D(4) dopamine receptor	0	2	0	3
D(1B) dopamine receptor	0	2	0	3
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	2	1	3
UDP-glucuronosyltransferase 1A4	0	1	0	3
Alpha-2A adrenergic receptor	0	2	1	3
Alpha-1D adrenergic receptor	0	6	1	7
Sodium-dependent noradrenaline transporter	0	4	1	5
Sodium-dependent dopamine transporter	0	5	0	5
Histamine H2 receptor	0	5	2	7
Alpha-1D adrenergic receptor	0	4	1	6
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	6	1	7
5-hydroxytryptamine receptor 2C	0	6	1	7
5-hydroxytryptamine receptor 1B	0	6	0	6
Trypanothione reductase	0	4	0	4
D(4) dopamine receptor	0	4	0	4
Histamine H1 receptor	0	2	4	6
Sodium-dependent serotonin transporter	0	10	0	10
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
5-hydroxytryptamine receptor 7	0	2	1	3
Histamine H1 receptor	0	8	2	10
Mu-type opioid receptor	0	6	3	10
D(3) dopamine receptor	0	5	0	6
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	2	0	3
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	6	2	9
Kappa-type opioid receptor	0	6	2	9
5-hydroxytryptamine receptor 2B	0	6	1	7
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	6	1	7
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
5-hydroxytryptamine receptor 6	0	8	1	9
5-hydroxytryptamine receptor 7	0	6	0	6
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Sodium-dependent dopamine transporter	0	2	0	2
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
D	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	3	2	5
Sodium channel protein type 10 subunit alpha	0	1	0	1
Guanine nucleotide-binding protein G	10	0	0	10
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
endonuclease IV	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	12	0	0	12
neuropeptide S receptor isoform A	4	0	0	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
dopamine D1 receptor	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glucocorticoid receptor	0	10	2	17
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	10	0	10
Corticosteroid-binding globulin	0	3	0	3
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	1	0	2
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Vasopressin V2 receptor	0	2	2	4
Oxytocin receptor	0	2	3	5
Vasopressin V1a receptor	0	4	3	7
Vasopressin V1b receptor	0	2	2	4
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	2	1	3
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Lysine-specific demethylase 6B	0	1	0	1
Lysine-specific demethylase 4A	0	3	1	4
Lysine-specific demethylase 5A	0	1	0	1
Flavin reductase (NADPH)	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Lysine-specific demethylase 6A	0	1	0	1
Lysine-specific demethylase 5C	0	1	0	1
Lysine-specific demethylase 2B	0	1	0	1
Deoxyhypusine hydroxylase	0	2	0	2
Lysine-specific demethylase 2A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
NAD	0	1	0	1
Cholinesterase	0	2	0	2
NAD	0	1	0	2
Mitogen-activated protein kinase 1	0	1	0	1
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Integrase	0	2	0	2
G-protein coupled receptor 35	0	2	2	4
Sterol O-acyltransferase 2	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
Multidrug resistance-associated protein 5	0	1	0	1
Equilibrative nucleoside transporter 2	0	1	0	1
Liver carboxylesterase 1	0	1	0	3
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Histone deacetylase 8	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bromodomain-containing protein 4	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Androgen receptor	0	3	1	4
Tissue factor	0	2	0	2
Histone deacetylase-like amidohydrolase	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Solute carrier family 22 member 4	0	1	0	1
Genome polyprotein	0	1	1	2
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	2	0	0	2
large T antigen	0	1	0	1
Estrogen receptor	0	4	0	4
UDP-glucuronosyltransferase 2B7	0	2	0	5
Alpha-synuclein	3	3	0	6
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Lanosterol 14-alpha demethylase	0	0	1	1
Olfactory receptor 51E2	0	0	3	3
UDP-glucuronosyltransferase 1A10	0	0	0	1
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
Chain A, Dihydrofolate reductase	0	0	1	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	2	5
Aldo-keto reductase family 1 member B1	0	5	0	6
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Sodium/bile acid cotransporter	0	2	0	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain A, Glutamine Binding Protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Asc-type amino acid transporter 1	0	1	0	1
Aldo-keto reductase family 1 member B10	0	0	0	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	9	0	10
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	2	4
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	1	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 3	0	2	0	3
Plasma kallikrein	0	0	0	5
Macrophage migration inhibitory factor	0	3	0	3
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Solute carrier family 22 member 1	0	1	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Stromelysin-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Urease subunit alpha	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Urease subunit beta	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Chain A, Purine-nucleoside Phosphorylase	0	1	0	1
Chain C, Xanthine dehydrogenase/oxidase	0	0	1	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Interleukin-8	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Acetylcholinesterase	0	3	0	3
Acetylcholinesterase	0	0	1	1
Lysosomal protective protein	0	1	0	1
Fatty acid synthase	0	1	0	1
Acetylcholinesterase	0	3	1	5
Liver carboxylesterase	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	4	0	4
Phospholipase A-2-activating protein	0	4	0	4
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
PINK1	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
Large neutral amino acids transporter small subunit 1	0	2	0	2
Kappa-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	1	6
Glutaminyl-peptide cyclotransferase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
pyruvate kinase	1	0	0	1
estrogen receptor beta isoform 1	0	2	0	2
Cystathionine gamma-lyase	0	2	0	2
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Amine oxidase [flavin-containing] A	0	2	0	2
Cruzipain	0	1	0	1
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Serine racemase	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	4
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain A, PROTEIN (5-AMINOLAEVULINIC ACID DEHYDRATASE)	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)	0	1	0	1
Chain L, Igg2b-kappa 40-50 Fab (light Chain)	0	1	0	1
Chain A, Na, K-ATPase alpha subunit	0	0	1	1
STAT3, partial	0	1	0	1
Kruppel-like factor 5	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	2
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	3
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	2
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	2
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	2
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Pyruvate kinase, M2 isozyme	0	1	0	1
Chain A, Phosphonopyruvate hydrolase	0	1	0	1
Chain A, Phosphoenolpyruvate-protein phosphotransferase	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase 1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
vasopressin V1b receptor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Tumor necrosis factor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
Chitotriosidase-1	0	3	1	4
Endochitinase B1	0	3	1	4
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Olfactory receptor class A-like protein 1	0	0	1	1
Tyrosine-protein kinase Lck	0	0	1	2
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
Chain A, PROTEIN (CATECHOL OXIDASE)	0	1	0	1
Tyrosinase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Gamma-aminobutyric acid	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Growth factor receptor-bound protein 2	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	2
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
heat shock protein HSP 90-alpha isoform 2	0	2	0	2
60 kDa chaperonin	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Glutamate 5-kinase	0	0	0	1
Free fatty acid receptor 2	0	1	1	2
Free fatty acid receptor 2	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
Beta-2 adrenergic receptor	0	2	0	3
Beta-3 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	4
Alpha-1B adrenergic receptor	0	0	1	2
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
Pyridoxal kinase	0	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
NS5	0	0	2	2
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
tumor necrosis factor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Prothrombin	0	1	0	1
Coagulation factor X	0	2	0	2
Coagulation factor XII	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
photoreceptor-specific nuclear receptor	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
Protein-arginine deiminase type-4	0	3	0	3
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	3	0	3
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
P2Y purinoceptor 13	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, Purine nucleoside phosphorylase	0	1	0	1
Chain A, Purine nucleoside phosphorylase DeoD-type	0	1	0	1
MSH	0	0	0	1
Hsf1 protein	0	0	1	2
Programmed cell death protein 4	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Spindlin-1	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Receptor-type tyrosine-protein phosphatase F	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (1,172)

Protein Targets (1,520)

Hemoglobinopathies

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (1,172)

Drugs Studied (277)

Protein Targets (1,520)