Meningitis, Pneumococcal

An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)

Synonym
Meningitis, Pneumococcal

Excerpt	Reference
"Mortality in pneumococcal meningitis is high."	( Almirante, B; Campos, L; Cortés, E; del Valle, O; Gasser, I; Pahissa, A; Pigrau, C, 1995)
"Adults who survive pneumococcal meningitis are at significant risk for long-term neuropsychological abnormalities."	( de Gans, J; Dreschler, WA; Hoogman, M; Schmand, BA; van de Beek, D; Weisfelt, M, 2006)
"Pneumococcal meningitis is a severe infectious disease of the central nervous system, associated with acute inflammation and might cause damage to the host, such as deafness, blindness, seizure, and learning deficits."	( Barichello, T; Cipriano, AL; Comim, CM; Costa, CS; Generoso, JS; Milioli, G; Moreira, AP; Quevedo, J; Teixeira, AL; Vilela, MC, 2012)
"Pneumococcal meningitis is associated with a significant mortality rate and neurologic sequelae."	( Barichello, T; Cipriano, AL; Comim, CM; Dal-Pizzol, F; Generoso, JS; Petronilho, F; Quevedo, J; Santos, AL; Silvestre, C, 2011)
"Pneumococcal meningitis is associated with the highest fatality case ratios in the world."	( Barichello, T; Comim, CM; Dal-Pizzol, F; Generoso, JS; Michelon, CM; Mina, F; Otaran, P; Quevedo, J; Santos, AL; Savi, GD; Steckert, AV, 2012)
"Pneumococcal meningitis is a life-threatening disease characterized by an acute purulent infection affecting piamater, arachnoid and the subarachnoid space."	( Almeida, SM; Barichello, T; Collodel, A; Generoso, JS; Moreira, AP, 2012)
"Neuronal injury in pneumococcal meningitis is a consequence of microglial activation and direct toxicity by bacterial products and systemic inflammation."	( Gerber, J; Nau, R; Redlich, S; Ribes, S; Schmidt, H; Tauber, SC, 2012)
"Pneumococcal meningitis is a life-threatening disease characterized by an acute infection affecting the pia matter, arachnoid and subarachnoid space."	( Barichello, T; Ceretta, RA; Comim, CM; Crippa, JA; Generoso, JS; Moreira, AP; Quevedo, J; Simões, LR; Teixeira, AL; Vilela, MC; Zuardi, AW, 2012)
"Pneumococcal meningitis is characterized by a severe inflammatory reaction in the subarachnoid and ventricular space of the brain, disruption of the blood-brain barrier, hearing loss, and neurologic sequelae in as many as 27% of surviving patients."	( Barichello, T; Comim, CM; Danielski, LG; Dominguini, D; Florentino, D; Generoso, JS; Petronilho, F; Quevedo, J; Sangiogo, G; Simões, LR, 2014)
"Pneumococcal meningitis is a lethal form of bacterial infection in the central nervous system that often causes lifelong neurological sequelae, despite therapeutic advances."	( Ball, HJ; Funakoshi, H; Hunt, NH; Kanai, M; McGregor, IS; McQuillan, JA; Nakamura, T; Too, LK, 2014)
"Pneumococcal meningitis is associated with neurologic sequelae, such as learning and memory impairment."	( Barichello, T; Generoso, Jda S; Goncalves, JC; Goularte, Jde A; Petronilho, F; Quevedo, J; Rodrigues, DH; Simoes, LR; Tashiro, MH; Teixeira, AL; Vilela, MC; Vuolo, F, 2014)
"Pneumococcal meningitis is a serious infection of the central nervous system (CNS) with high fatality rates that causes reduced psychomotor performance, slight mental slowness, impairments in attention executive functions and learning and memory deficiencies."	( Barichello, T; Ceretta, RA; Faller, CJ; Generoso, JS; Lopes-Borges, J; Petronilho, F; Quevedo, J; Simões, LR; Valvassori, SS, 2015)
"Pneumococcal meningitis is associated with high morbidity and mortality rates."	( Grandgirard, D; Leib, SL; Liechti, FD; Stüdle, N; Theurillat, R; Thormann, W, 2014)
"Pneumococcal meningitis is associated with substantial mortality and morbidity."	( Aronica, E; Brouwer, MC; Engelen-Lee, JY; van de Beek, D, 2016)
"Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS) with a high mortality rate."	( Barichello, T; Dominguini, D; Generoso, JS; Jornada, LK; Quevedo, J; Sharin, VS; Simões, LR; Souza, LB; Teixeira, AL; Valvassori, SS, 2016)
"Pneumococcal meningitis is the most common and severe form of bacterial meningitis."	( Baas, F; Brouwer, MC; Ferwerda, B; Kasanmoentalib, ES; Schwaeble, WJ; Tanck, MW; Valls Seron, M; van de Beek, D; van der Ende, A; Zwinderman, AH, 2017)
"Pneumococcal meningitis is one of the most common infectious diseases with a high-mortality rate and long-term neurological sequelae, affecting up to 50% of survivors."	( Liu, X; Wang, Y; Xu, G, 2018)
"Pneumococcal meningitis is associated with high mortality and morbidity rates."	( Buri, M; Grandgirard, D; Leib, SL; Muri, L; Perny, M, 2018)
"Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss."	( Grandgirard, D; Le, ND; Leib, SL; Muri, L; Zemp, J, 2019)
"Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS), and half of the survivors of meningitis suffer from neurological sequelae."	( Barichello, T; Bhatti, GS; Collodel, A; Dal-Pizzol, F; Dominguini, D; Faller, CJ; Generoso, JS; Giridharan, VV; Petronilho, F; Tardin, F, 2021)
"Pneumococcal meningitis is a devastating disease that requires adequate meningeal antibiotic penetration to limit the mortality."	( Duval, X; El Helali, N; Gregoire, M; Guilhaumou, R; Le Turnier, P; Lemaitre, F; Leroy, AG; Pilmis, B; Revest, M; Velly, LJ, 2021)

Excerpt	Reference
"Pneumococcal meningitis has a high morbidity and mortality rate despite effective antibiotherapy, probably due to an exaggerated inflammatory response of the CNS."	( Cabellos, C; Gudiol, F; Martínez-Lacasa, J; Martos, A; Viladrich, PF, 1995)
"Treatment of pneumococcal meningitis has become problematic because of the emergence of penicillin- and cephalosporin-resistant strains and because of the concern that dexamethasone therapy might reduce penetration of antibiotics into the cerebrospinal fluid (CSF)."	( Hickey, SM; McCracken, GH; Olsen, KD; París, MM; Shelton, S; Uscher, MI, 1994)
"Typical features of pneumococcal meningitis have been demonstrated in rats inoculated with Streptococcus pneumoniae."	( Bass, R; Engelhard, D; Shohami, E; Trembovler, V, 1996)

Excerpt	Reference
"The optimal treatment of pneumococcal meningitis caused by strains with a cefotaxime/ceftriaxone MIC >2 microg/ml is unknown, although the addition of rifampin to the initial combination is generally recommended."	( Kaplan, SL, 2002)
"In a mouse model of ceftriaxone-treated pneumococcal meningitis, spatial memory and motor performance of TNF-alpha-deficient (n = 57) and control mice (n = 55) were investigated."	( Böttcher, T; Bunkowski, S; Gerber, J; Hahn, M; Nau, R; Siemer, A, 2004)
"To determine whether treating pneumococcal meningitis with a combined antibiotic and steroid regime will prevent cochlear damage, a common pneumococcal meningitis side effect."	( Addison, J; Kim, HH; Richter, CP; Suh, E; Trune, DR, 2007)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	361 (36.28)	23.3326
1990's	224 (22.51)	12.5806
2000's	228 (22.91)	18.1394
2010's	152 (15.28)	28.8240
2020's	30 (3.02)	9.53

Drug	Relationship Strength	Studies	Trials
2,3-diphosphoglycerate	low	1	0
3-hydroxyanthranilic acid	low	1	0
3-hydroxykynurenine	low	1	0
beta-alanine	medium	2	1
butyric acid	low	1	0
choline	low	2	0
chlorine	low	1	0
salicylic acid	low	2	0
lactic acid	low	23	0
glycerol	medium	4	2
hydrogen carbonate	low	1	0
kynurenine	low	4	0
endolysin	low	1	0
melatonin	low	1	0
nitrates	low	2	0
nitrites	low	4	0
nitrous oxide	low	1	0
phosphorylcholine	low	2	0
pyruvic acid	low	2	0
uric acid	low	3	0
3-aminobenzamide	low	1	0
phenytoin	low	2	0
hydroxyindoleacetic acid	low	1	0
7-nitroindazole	low	1	0
acetaminophen	low	1	0
pimagedine	low	2	0
amiodarone	low	1	0
antipyrine	low	1	0
benzothiazide	low	2	0
cefuroxime	medium	12	4
chloroquine	low	1	0
chlorothiazide	low	1	0
ciprofloxacin	low	10	0
deferoxamine	low	3	0
diclofenac	low	1	0
pentetic acid	low	1	0
etodolac	low	1	0
fluoxetine	low	1	0
gentamicin	medium	17	1
halothane	low	1	0
ibuprofen	low	1	0
lidocaine	low	1	0
imipramine	low	2	0
indomethacin	low	3	0
isoniazid	low	1	0
isoproterenol	low	1	0
staurosporine aglycone	low	1	0
ketorolac	low	2	0
kynurenic acid	low	1	0
edaravone	low	1	0
metformin	low	1	0
modafinil	low	1	0
apnea	low	1	0
activins	low	1	0
naratriptan	low	1	0
neostigmine	low	1	0
nimodipine	low	2	0
ofloxacin	low	9	0
pentobarbital	low	2	0
pentoxifylline	low	2	0
probenecid	low	2	0
procaine	low	1	0
sevoflurane	low	1	0
sulfadiazine	medium	7	1
sulfamerazine	low	2	0
sulfamethazine	low	1	0
sulfamethoxazole	low	5	0
sulfanilamide	low	4	0
sulfathiazole	low	3	0
sulfisoxazole	low	2	0
gatifloxacin	low	2	0
tetraethylammonium	low	1	0
thalidomide	low	1	0
tolmetin	low	1	0
trimethoprim	low	5	0
urethane	low	1	0
mitomycin	low	1	0
corticosterone	low	3	0
prednisolone	medium	8	1
cephaloridine	low	8	0
thymidine	low	1	0
spironolactone	low	1	0
prednisone	medium	10	1
penicillin g	medium	84	2
triiodothyronine	low	1	0
alanine	low	2	0
serine	low	1	0
chloramphenicol	medium	111	17
glutamine	low	1	0
cephalothin	low	7	0
kanamycin a	low	5	0
bromodeoxyuridine	low	3	0
carbostyril	low	7	0
tyrosine	low	5	0
methicillin	low	3	0
cloxacillin	low	1	0
oxacillin	medium	1	1
ampicillin	medium	100	16
mannitol	low	4	0
tryptophan	low	5	0
isoleucine	low	1	0
arginine	low	3	0
methylprednisolone	medium	14	1
penicillin v	low	4	0
pyrrolidonecarboxylic acid	low	1	0
framycetin	low	1	0
iodohippuric acid	low	1	0
indazoles	low	1	0
thiazoles	low	1	0
nitroblue tetrazolium	low	2	0
evans blue	low	1	0
betamethasone	low	3	0
emetine	low	1	0
malondialdehyde	low	1	0
gentian violet	low	5	0
acetylcysteine	low	6	0
erythromycin	low	21	0
rhodamine 6g	low	1	0
vancomycin	medium	101	4
spectinomycin	low	1	0
dronabinol	low	1	0
methionine sulfoximine	low	1	0
streptomycin	medium	18	1
carbenicillin	medium	2	1
floxacillin	low	1	0
vidarabine	low	1	0
silver	low	1	0
technetium	low	2	0
ytterbium	low	1	0
trolamine salicylate	low	4	0
stanozolol	low	1	0
clodronic acid	low	3	0
cephalexin	low	1	0
danazol	low	1	0
4-methoxyamphetamine	low	2	0
transferrin	low	2	0
glutamic acid	low	3	0
cefazolin	low	1	0
amoxicillin	low	17	0
substance p	low	2	0
ribavirin	low	1	0
amikacin	low	1	0
ng-nitroarginine methyl ester	low	1	0
propiconazole	low	1	0
piperacillin	low	1	0
cefoperazone	low	1	0
moxalactam	low	5	0
cefaclor anhydrous	low	1	0
simvastatin	low	1	0
clinafloxacin	low	3	0
zolmitriptan	low	1	0
trovafloxacin	low	9	0
glucose, (beta-d)-isomer	low	1	0
thomsen-friedenreich antigen	low	1	0
peroxynitric acid	low	1	0
cephalosporin c	medium	126	7
ritipenem	low	1	0
cefpimizole	low	1	0
oxindanac	low	2	0
ljc 10627	low	1	0
masoprocol	low	1	0
aspoxicillin	low	1	0
panipenem	low	2	0
grepafloxacin	low	2	0
doripenem	low	1	0
oxazolidin-2-one	low	6	0
clarithromycin	low	4	0
ethylhydrocupreine	low	1	0
fibrinogen	low	2	0
cephacetrile	low	1	0
glycidyl nitrate	low	2	0
arginyl-glycyl-aspartic acid	low	1	0
vitamin b 6	low	4	0
imipenem, anhydrous	low	8	0
bosentan anhydrous	low	1	0
u 74389f	low	1	0
1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	2	0
panipenem-betamipron	medium	2	1
peroxynitrous acid	low	3	0
head activator peptide	low	1	0
garenoxacin	low	2	0
1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate monohydrate	low	1	0
carbapenems	low	5	0
beta-lactams	low	8	0
levofloxacin	low	10	0
ertapenem	low	2	0
moxifloxacin	low	7	0
cyc 202	low	1	0
technetium tc 99m pentetate	low	1	0
sb 203580	low	1	0
troleandomycin	low	1	0
cortisone	low	4	0
3-nitrotyrosine	low	3	0
trimethoprim, sulfamethoxazole drug combination	low	8	0
lithium chloride	low	1	0
glycogen	low	1	0
n-acetylneuraminic acid	low	2	0
bradykinin	low	1	0
nitroarginine	low	1	0
meropenem	low	19	0
netilmicin	low	2	0
linezolid	low	6	0
n-formylmethionine leucyl-phenylalanine	low	3	0
clindamycin	low	4	0
fosfomycin	low	7	0
zithromax	low	3	0
cefamandole	low	3	0
bromochloroacetic acid	low	1	0
cefpiramide	low	1	0
phenyl-n-tert-butylnitrone	low	4	0
cannabidiol	low	1	0
arginine vasopressin	low	1	0
chloramphenicol succinate	low	1	0
n-benzoylalanine	low	2	0
digoxin	low	1	0
lincomycin	low	2	0
thiopental	low	1	0
maraviroc	low	1	0
lithium	low	1	0
quinine	low	1	0
telavancin	low	1	0
rs-130830	low	1	0
myelin basic protein	low	2	0
dinoprostone	low	4	0
amphotericin b	low	2	0
diosmetin	low	1	0
ro 61-8048	low	1	0
phenylephrine hydrochloride	medium	7	1
deamino arginine vasopressin	low	2	0
cytochalasin b	low	1	0
sulfenamide	low	1	0
ag 127	low	2	0
bay 11-7085	low	1	0
dextromethorphan	low	1	0
cefodizime	low	1	0
phosphorus	low	1	0
ceftriaxone	low	3	0
cefepime	low	4	0
hr 810	low	4	0
cefotaxime	medium	90	9
dizocilpine maleate	low	1	0
cilastatin	low	3	0
apalcillin	low	1	0
ro 25-6981	low	1	0
3-tyrosine	low	1	0
cefmenoxime	low	2	0
gemifloxacin	low	2	0
ro 32-3555	low	1	0
ppi-0903	low	2	0
mocetinostat	low	5	0
oxadiazoles	low	1	0
losartan potassium	low	1	0
pituitrin	low	3	0
virginiamycin	low	4	0
clove	low	2	0
icatibant	low	1	0
nad	low	1	0
cytochrome c-t	low	1	0
oritavancin	low	2	0
endothelin-1	low	1	0
cilastatin, imipenem drug combination	low	2	0
lm11a-31	low	1	0
ro13-9904	medium	190	18
sodium ethylxanthate	low	2	0
quinupristin	low	1	0
quinupristin-dalfopristin	low	3	0
fps-zm1	low	1	0
piperidines	low	3	0
interleukin-8	low	6	0
tetracycline	low	20	0
chlortetracycline	low	3	0
minocycline	low	1	0
salicylates	low	1	0
warfarin	low	2	0
demeclocycline	low	1	0
rolitetracycline	low	2	0
mysteclin f	low	1	0
bacitracin a	low	1	0
calca protein, human	medium	2	1
transforming growth factor beta	low	3	0
sybr green i	low	1	0
technetium tc 99m sulfur colloid	low	1	0
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	low	1	0
hyaluronoglucosaminidase	low	1	0
daptomycin	medium	14	1
vitamin b 12	low	2	0
bb 1101	low	1	0
dalfopristin	low	1	0
cyclosporine	low	1	0
apyrase	low	1	0
muramidase	low	4	0
acyclovir	low	1	0
folic acid	low	1	0
rifampin	medium	32	1
allopurinol	low	2	0
lipoteichoic acid	low	10	0
eye	low	3	0
phosphorus radioisotopes	low	1	0

Protein Targets (2,021)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	38	0	0	38
Chain A, Cruzipain	14	0	0	14
regulator of G-protein signaling 4	24	0	0	24
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	6	0	0	6
Cannabinoid receptor 1	0	4	1	5
Cannabinoid receptor 1	0	6	2	10
Cannabinoid receptor 2	0	4	3	9
Cannabinoid receptor 2	0	3	0	3
Chain A, HADH2 protein	18	0	0	18
Chain B, HADH2 protein	18	0	0	18
Chain A, 2-oxoglutarate Oxygenase	29	0	0	29
Chain A, Ferritin light chain	11	0	0	11
aldehyde dehydrogenase 1 family, member A1	45	0	0	45
cytochrome P450 2D6 isoform 1	11	0	0	11
cytochrome P450 2C9 precursor	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	19	0	0	19
lamin isoform A-delta10	47	0	0	47
Poly [ADP-ribose] polymerase 2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	2	0	2
Poly [ADP-ribose] polymerase 1	0	1	0	1
Histamine H2 receptor	19	1	1	21
Transporter	0	8	0	8
ATP-dependent phosphofructokinase	25	0	0	25
Chain A, Phenazine biosynthesis protein phzF	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	12	0	0	12
thioredoxin reductase	44	0	0	44
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
GLS protein	32	0	0	32
TDP1 protein	65	0	0	65
isocitrate dehydrogenase 1, partial	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	19	0	0	19
DNA polymerase iota isoform a (long)	21	0	0	21
DNA polymerase kappa isoform 1	18	0	0	18
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
Caspase-7	0	0	0	1
Caspase-9	0	2	0	3
large T antigen	0	1	0	1
Kynureninase	0	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	18	0	0	18
phosphopantetheinyl transferase	25	0	0	25
bromodomain adjacent to zinc finger domain 2B	16	0	0	16
euchromatic histone-lysine N-methyltransferase 2	65	0	0	65
pyruvate kinase PKM isoform a	2	0	0	2
geminin	65	0	0	65
Glycoprotein hormones alpha chain	1	0	0	1
Guanine nucleotide-binding protein G	6	0	0	6
Tubulin--tyrosine ligase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	4	0	4
5-hydroxytryptamine receptor 2C	0	6	1	7
5-hydroxytryptamine receptor 2A	0	10	2	12
5-hydroxytryptamine receptor 1A	0	5	1	6
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 2B	0	7	1	8
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	11	3	14
Sodium-dependent serotonin transporter	0	10	0	10
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
endonuclease IV	10	0	0	10
Bloom syndrome protein isoform 1	20	0	0	20
cytochrome P450 2C19 precursor	9	0	0	9
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	8	0	0	8
flap endonuclease 1	26	0	0	26
nuclear receptor ROR-gamma isoform 1	16	0	0	16
survival motor neuron protein isoform d	19	0	0	19
muscleblind-like protein 1 isoform 1	6	0	0	6
muscarinic acetylcholine receptor M1	23	0	0	23
neuropeptide S receptor isoform A	7	0	0	7
Aromatase	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Nitric oxide synthase, endothelial	0	4	0	6
Nitric oxide synthase, endothelial	0	5	0	6
Nitric oxide synthase, brain	0	7	0	9
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, inducible	0	6	0	7
Nitric oxide synthase, inducible	0	5	1	9
Nitric oxide synthase, endothelial	0	1	0	1
RAR-related orphan receptor gamma	40	0	0	40
ATAD5 protein, partial	13	0	0	13
Microtubule-associated protein tau	22	0	0	23
Smad3	13	0	0	13
thyroid stimulating hormone receptor	29	0	0	29
nuclear receptor subfamily 1, group I, member 3	33	0	0	33
progesterone receptor	30	0	0	30
EWS/FLI fusion protein	33	0	0	33
retinoic acid nuclear receptor alpha variant 1	45	0	0	45
retinoid X nuclear receptor alpha	39	0	0	39
estrogen-related nuclear receptor alpha	55	0	0	55
estrogen nuclear receptor alpha	82	0	0	82
peroxisome proliferator activated receptor gamma	32	0	0	32
aryl hydrocarbon receptor	24	0	0	24
chromobox protein homolog 1	38	0	0	38
thyroid hormone receptor beta isoform 2	48	0	0	48
peripheral myelin protein 22	24	0	0	24
cytochrome P450 3A4 isoform 1	22	0	0	22
Gamma-aminobutyric acid receptor subunit pi	22	4	1	28
ATP-binding cassette sub-family C member 3	0	54	0	54
Multidrug resistance-associated protein 4	0	54	0	57
Solute carrier family 22 member 6	0	20	0	21
Carbonic anhydrase 12	0	5	0	7
UDP-glucuronosyltransferase 1A9	0	2	0	6
Bile salt export pump	0	16	0	16
Voltage-dependent calcium channel gamma-2 subunit	20	0	0	20
Bile salt export pump	0	81	0	81
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	15	0	21
Carbonic anhydrase 2	0	15	1	22
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	4	1	6
Cytochrome P450 1A2	0	10	0	13
Prostaglandin G/H synthase 1	0	9	0	10
Carbonic anhydrase 3	0	4	0	6
Cytochrome P450 3A4	0	22	1	26
Cytochrome P450 2D6	0	16	0	18
Cytochrome P450 2C9	0	27	0	29
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	22	4	1	28
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	22	4	1	28
Gamma-aminobutyric acid receptor subunit gamma-2	22	4	1	28
UDP-glucuronosyltransferase 1-6	0	3	0	5
Glutamate receptor 2	20	3	2	26
Gamma-aminobutyric acid receptor subunit alpha-5	22	4	1	28
Gamma-aminobutyric acid receptor subunit alpha-3	22	4	1	28
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	5
Carbonic anhydrase 4	0	8	0	10
Prostaglandin G/H synthase 1	0	11	0	11
Carbonic anhydrase 6	0	6	0	8
Gamma-aminobutyric acid receptor subunit gamma-1	22	4	1	28
Gamma-aminobutyric acid receptor subunit alpha-2	22	4	1	28
Gamma-aminobutyric acid receptor subunit alpha-4	22	4	1	28
Gamma-aminobutyric acid receptor subunit gamma-3	22	4	1	28
Gamma-aminobutyric acid receptor subunit alpha-6	22	4	1	28
Carbonic anhydrase 5A, mitochondrial	0	5	0	8
Prostaglandin G/H synthase 2	0	10	2	13
Carbonic anhydrase 7	0	4	0	6
Nuclear receptor ROR-gamma	12	1	1	14
Cytochrome P450 2J2	0	18	0	18
Gamma-aminobutyric acid receptor subunit alpha-1	22	4	1	28
Gamma-aminobutyric acid receptor subunit beta-3	22	4	1	28
Gamma-aminobutyric acid receptor subunit beta-2	22	4	1	28
Carbonic anhydrase 9	0	7	0	9
GABA theta subunit	22	4	1	28
Canalicular multispecific organic anion transporter 1	0	53	0	53
Carbonic anhydrase 15	0	7	0	9
Carbonic anhydrase 13	0	3	0	4
Gamma-aminobutyric acid receptor subunit epsilon	22	4	1	28
Carbonic anhydrase 14	0	4	0	6
Carbonic anhydrase 5B, mitochondrial	0	4	0	7
toxin B	0	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
acetylcholinesterase	13	0	0	13
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	9	0	0	9
pregnane X receptor	10	0	0	10
USP1 protein, partial	23	0	0	23
NFKB1 protein, partial	13	0	0	13
Thrombopoietin	5	0	0	5
AR protein	63	0	0	63
glucocorticoid receptor [Homo sapiens]	47	0	0	47
farnesoid X nuclear receptor	30	0	0	30
vitamin D (1,25- dihydroxyvitamin D3) receptor	31	0	0	31
arylsulfatase A	22	0	0	22
D(1A) dopamine receptor	9	0	0	9
thyroid hormone receptor beta isoform a	19	0	0	19
heat shock protein beta-1	16	0	0	16
Histone deacetylase 3	0	5	0	5
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
Ataxin-2	23	0	0	23
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	4	0	4
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase	0	2	0	3
activating transcription factor 6	16	0	0	16
Histone H2A.x	17	0	0	17
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
Solute carrier family 22 member 1	0	9	0	15
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	7
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	3	0	8
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	17	0	20
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	17	0	20
Thymidine kinase	0	1	0	2
Epidermal growth factor receptor	0	6	2	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	3	1	5
Glutamate receptor ionotropic, NMDA 1	0	10	2	15
Proton-coupled amino acid transporter 1	0	4	0	4
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	3
interleukin 8	15	0	0	15
estrogen receptor 2 (ER beta)	22	0	0	22
IDH1	17	0	0	17
transcriptional regulator ERG isoform 3	7	0	0	7
ras-related protein Rab-9A	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	54	0	0	54
Polyphenol oxidase 2	0	3	0	5
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	39	0	0	39
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	5	1	6
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
TAR DNA-binding protein 43	9	0	0	9
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	7
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Aminoglycoside 3'-phosphotransferase	0	0	0	2
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
SMAD family member 2	12	0	0	12
Fumarate hydratase	7	0	0	7
PPM1D protein	13	0	0	13
SMAD family member 3	12	0	0	12
caspase 7, apoptosis-related cysteine protease	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
pregnane X nuclear receptor	37	0	0	37
G	24	0	0	24
cytochrome P450 2D6	23	0	0	23
polyprotein	7	0	0	7
peroxisome proliferator-activated receptor delta	25	0	0	25
caspase-3	7	0	0	7
thyroid stimulating hormone receptor	16	0	0	16
v-jun sarcoma virus 17 oncogene homolog (avian)	17	0	0	17
cellular tumor antigen p53 isoform a	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	17	0	0	17
huntingtin isoform 2	3	0	0	3
mitogen-activated protein kinase 1	13	0	0	13
serine/threonine-protein kinase mTOR isoform 1	10	0	0	10
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
urokinase-type plasminogen activator precursor	12	0	0	12
plasminogen precursor	12	0	0	12
urokinase plasminogen activator surface receptor precursor	12	0	0	12
lethal factor (plasmid)	17	0	0	17
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	0	0	10
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Solute carrier organic anion transporter family member 1A4	0	7	0	9
Voltage-dependent L-type calcium channel subunit alpha-1F	0	11	0	11
5-hydroxytryptamine receptor 4	0	4	0	4
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	35	0	0	35
HLA class I histocompatibility antigen, B alpha chain	24	0	0	24
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	2	4
Integrin beta-3	5	1	1	7
Tyrosine-protein kinase Fyn	0	2	2	4
ATP-dependent translocase ABCB1	0	5	0	5
Aldo-keto reductase family 1 member B1	0	7	0	7
Muscarinic acetylcholine receptor M2	0	6	0	6
Muscarinic acetylcholine receptor M4	0	5	0	5
ATP-dependent translocase ABCB1	0	15	1	21
Integrin alpha-IIb	5	1	1	7
Beta-1 adrenergic receptor	0	4	1	5
Muscarinic acetylcholine receptor M5	0	7	0	7
Alpha-2A adrenergic receptor	0	11	0	11
Adenosine receptor A3	0	10	0	10
Cytochrome P450 2C8	0	3	0	3
Thyroid hormone receptor alpha	0	3	2	5
Thyroid hormone receptor beta	0	3	2	5
Muscarinic acetylcholine receptor M1	0	9	0	9
Beta-3 adrenergic receptor	0	5	1	6
D(2) dopamine receptor	0	8	0	8
Androgen receptor	0	14	0	15
Alpha-1B adrenergic receptor	0	16	0	16
Lethal factor	0	2	0	2
Alpha-2B adrenergic receptor	0	10	0	10
Thyroid hormone receptor beta	0	2	0	2
Muscarinic acetylcholine receptor M3	0	9	0	9
ATP-dependent translocase ABCB1	0	5	0	5
Substance-K receptor	0	8	0	8
D(1A) dopamine receptor	0	10	0	10
D(4) dopamine receptor	0	4	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	9	1	10
Histamine H2 receptor	0	4	0	4
Endothelin-1 receptor	0	8	0	8
5-hydroxytryptamine receptor 2A	0	10	0	10
5-hydroxytryptamine receptor 2C	0	6	0	6
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	4	1	7
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	7	0	7
D(3) dopamine receptor	0	10	1	11
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	4	0	5
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	3	0	3
Kappa-type opioid receptor	0	7	0	7
5-hydroxytryptamine receptor 2B	0	2	0	2
C-C chemokine receptor type 2	0	4	0	4
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	17	0	17
D(1A) dopamine receptor	4	0	0	4
5-hydroxytryptamine receptor 6	0	7	0	7
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	22	1	3	26
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	11	0	11
Sodium-dependent dopamine transporter	0	13	1	14
Potassium voltage-gated channel subfamily H member 2	0	25	0	27
Voltage-dependent L-type calcium channel subunit alpha-1S	0	11	0	11
Voltage-dependent L-type calcium channel subunit alpha-1C	0	15	0	15
Sodium channel protein type 5 subunit alpha	0	7	0	7
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	4	0	4
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	24	0	0	24
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	7	0	7
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
cytochrome P450 2C9, partial	24	0	0	24
Chain A, Beta-lactamase	15	0	0	15
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	8
Beta-lactamase	0	0	0	8
Beta-lactamase	0	1	0	11
apical membrane antigen 1, AMA1	6	0	0	6
Beta-lactamase	0	0	0	5
DNA polymerase eta isoform 1	6	0	0	6
Beta-lactamase SHV-1	0	0	0	5
Beta-lactamase SHV-1	0	1	0	11
Beta-lactamase	0	1	0	11
Kappa-type opioid receptor	0	0	0	8
Solute carrier family 15 member 1	0	23	0	23
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	10
Solute carrier family 15 member 2	0	13	0	13
Beta-lactamase	0	0	0	6
Beta-lactamase	0	0	0	6
Solute carrier family 15 member 2	0	16	0	17
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	7
tumor necrosis factor	3	0	0	3
vitamin D3 receptor isoform VDRA	30	0	0	30
Cytochrome P450 2C19	0	13	0	15
Aurora kinase B	0	2	2	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	2	0	8
acid sphingomyelinase	3	0	0	3
GLI family zinc finger 3	50	0	0	50
Beta-lactamase	0	1	0	9
Beta-lactamase	0	0	0	8
Metallo-beta-lactamase type 2	0	0	1	9
Metallo-beta-lactamase VIM-11	0	0	0	8
Metallo-beta-lactamase VIM-2	0	0	0	8
Beta-lactamase	0	1	0	11
Metallo-beta-lactamase	0	0	0	7
Beta-lactamase	0	1	0	9
DNA polymerase beta	7	0	0	7
60 kDa heat shock protein, mitochondrial	0	7	0	7
Beta-lactamase OXA-7	0	0	0	5
10 kDa heat shock protein, mitochondrial	0	7	0	7
Angiopoietin-1 receptor	0	1	3	4
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Thiosulfate sulfurtransferase	0	7	0	7
Metallo-beta-lactamase VIM-13	0	0	0	8
Efflux transporter	0	1	0	5
Beta-lactamase	0	0	0	6
Beta-lactamase Toho-1	0	0	0	5
Beta-lactamase	0	1	0	5
Class D beta-lactamase	0	1	0	6
60 kDa chaperonin	0	7	0	7
Metallo-beta-lactamase	0	0	0	6
Beta-lactamase	0	1	0	7
Beta-lactamase	0	0	1	6
10 kDa chaperonin	0	7	0	7
Metallo-b-lactamase	0	0	0	14
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	10
Beta-lactamase class B VIM-2	0	0	1	17
Beta-lactamase VIM-1	0	0	0	8
67.9K protein	15	0	0	15
Nicotinate phosphoribosyltransferase	0	3	0	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	8	0	0	8
Cationic amino acid transporter 3	0	1	0	1
Translocator protein	0	0	1	1
Vasopressin V2 receptor	0	3	2	6
Oxytocin receptor	0	1	2	3
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	2	2	4
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	2	0	3
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	2	2	4
Integrin beta-1	0	2	0	2
Integrin alpha-V	0	1	0	1
Integrin alpha-5	0	1	0	1
Integrin beta-5	0	1	0	1
Nrf2	1	0	0	1
hypothetical protein, conserved	4	0	0	4
nonstructural protein 1	9	0	0	9
Parkin	8	0	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
Replicase polyprotein 1ab	0	3	3	6
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
peripheral myelin protein 22 isoform 1	16	0	0	16
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
M-phase phosphoprotein 8	10	0	0	10
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Amyloid-beta precursor protein	1	2	0	3
Replicase polyprotein 1ab	0	7	3	10
Alpha-synuclein	3	2	1	6
Luciferase	12	0	0	12
cytochrome P450 family 3 subfamily A polypeptide 4	32	0	0	32
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	8	2	13
Glutamate receptor ionotropic, NMDA 2B	0	8	2	13
Glutamate receptor ionotropic, NMDA 2C	0	8	2	13
Glutamate receptor ionotropic, NMDA 2D	0	8	2	13
Glutamate receptor ionotropic, NMDA 3B	0	8	2	13
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	8	2	13
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	27	0	0	27
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	14	3	22
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	5	1	6
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine phosphorylase	0	0	0	2
Thymidylate kinase	0	2	0	2
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	2	0	2
ATPase family AAA domain-containing protein 5	14	0	0	14
Chain A, Nitrile Hydratase alpha subunit	0	1	0	1
Chain B, Nitrile Hydratase beta subunit	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	16	0	0	16
Free fatty acid receptor 3	0	0	1	1
Solute carrier family 22 member 20	0	6	0	6
Solute carrier family 22 member 6	0	6	0	6
Methyl-accepting chemotaxis protein NahY	0	0	1	1
Acetylcholinesterase	0	3	0	3
L-lactate dehydrogenase A chain	0	2	0	2
Cytochrome P450 2C11	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	1	4
Cytochrome P450 2A6	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Alpha-2C adrenergic receptor	0	8	0	8
Cytochrome P450 2B6	0	1	1	2
Cytochrome P450 3A5	0	1	0	1
Cytochrome P450 3A7	0	1	0	1
Caspase-1	0	3	1	5
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Cholinesterase	0	3	0	3
N-acylethanolamine-hydrolyzing acid amidase	0	1	0	1
Cytochrome P450 1B1	0	6	0	6
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Transient receptor potential cation channel subfamily V member 1	0	1	1	2
Transient receptor potential cation channel subfamily M member 8	0	1	0	1
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
G-protein coupled receptor 55	0	1	2	3
Diacylglycerol lipase-alpha	0	1	0	1
Histamine H3 receptor	0	3	0	3
Dihydroxyacetone phosphate acyltransferase	0	0	0	3
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
importin subunit beta-1 isoform 1	5	0	0	5
serine/threonine-protein kinase PLK1	5	0	0	5
snurportin-1	5	0	0	5
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	2	0	2
streptokinase A precursor	0	0	12	12
Estrogen receptor	0	0	2	2
Estrogen receptor beta	0	0	2	2
Solute carrier family 22 member 7	0	6	0	9
Solute carrier family 22 member 11	0	9	0	11
Solute carrier family 22 member 8	0	12	0	13
Solute carrier family 22 member 7	0	7	0	9
Beta-lactamase	0	2	0	7
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase VIM-19	0	0	0	7
Beta-lactamase	0	1	0	7
Beta-lactamase	0	0	0	3
Solute carrier family 22 member 5	0	2	0	2
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	8
Beta-lactamase	0	0	0	3
Beta-lactamase TEM	0	4	0	11
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	7
Metallo-beta-lactamase VIM-2	0	0	0	7
Beta-lactamase	0	0	0	6
BlaVIM-1	0	0	0	6
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	7
Canalicular multispecific organic anion transporter 1	0	3	0	3
Glutathione reductase, mitochondrial	0	4	0	4
Glutathione peroxidase 1	0	2	0	2
Microsomal glutathione S-transferase 1	0	2	0	2
Beta-lactamase	0	2	0	5
Albumin	0	7	13	20
Beta-lactamase	0	0	0	3
D-amino-acid oxidase	0	1	0	1
Excitatory amino acid transporter 2	0	2	1	4
Beta-lactamase	0	1	0	5
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	5
Beta-lactamase IMP-1	0	0	0	5
Beta-lactamase	0	0	0	5
WRN	2	0	0	2
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
Solute carrier family 22 member 8	0	7	0	8
Beta-lactamase OXA-1	0	1	0	2
phosphoglycerate kinase	2	0	0	2
30S ribosomal protein S6	0	7	1	8
30S ribosomal protein S7	0	7	1	8
50S ribosomal protein L15	0	7	1	8
50S ribosomal protein L10	0	7	1	8
50S ribosomal protein L11	0	7	1	8
50S ribosomal protein L7/L12	0	7	1	8
50S ribosomal protein L19	0	7	1	8
50S ribosomal protein L1	0	7	1	8
50S ribosomal protein L20	0	7	1	8
50S ribosomal protein L27	0	7	1	8
50S ribosomal protein L28	0	7	1	8
50S ribosomal protein L29	0	7	1	8
50S ribosomal protein L31	0	7	1	8
50S ribosomal protein L31 type B	0	7	1	8
50S ribosomal protein L32	0	7	1	8
50S ribosomal protein L33	0	7	1	8
50S ribosomal protein L34	0	7	1	8
50S ribosomal protein L35	0	7	1	8
50S ribosomal protein L36	0	7	1	8
30S ribosomal protein S10	0	7	1	8
30S ribosomal protein S11	0	7	1	8
30S ribosomal protein S12	0	7	1	8
30S ribosomal protein S13	0	7	1	8
30S ribosomal protein S16	0	7	1	8
30S ribosomal protein S18	0	7	1	8
30S ribosomal protein S19	0	7	1	8
30S ribosomal protein S20	0	7	1	8
30S ribosomal protein S2	0	7	1	8
30S ribosomal protein S3	0	7	1	8
30S ribosomal protein S4	0	7	1	8
30S ribosomal protein S5	0	7	1	8
30S ribosomal protein S8	0	7	1	8
30S ribosomal protein S9	0	7	1	8
50S ribosomal protein L13	0	7	1	8
50S ribosomal protein L14	0	7	1	8
50S ribosomal protein L16	0	7	1	8
50S ribosomal protein L23	0	7	1	8
30S ribosomal protein S15	0	7	1	8
50S ribosomal protein L17	0	7	1	8
50S ribosomal protein L21	0	7	1	8
50S ribosomal protein L30	0	7	1	8
50S ribosomal protein L6	0	7	1	8
30S ribosomal protein S14	0	7	1	8
30S ribosomal protein S17	0	7	1	8
30S ribosomal protein S1	0	7	1	8
50S ribosomal protein L18	0	7	1	8
50S ribosomal protein L2	0	7	1	8
50S ribosomal protein L3	0	7	1	8
50S ribosomal protein L24	0	7	1	8
50S ribosomal protein L4	0	7	1	8
50S ribosomal protein L22	0	7	1	8
50S ribosomal protein L5	0	7	1	8
30S ribosomal protein S21	0	7	1	8
50S ribosomal protein L25	0	7	1	8
50S ribosomal protein L36 2	0	7	1	8
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase	0	5	0	7
Spike glycoprotein	0	1	3	4
Transmembrane protease serine 2	0	1	3	4
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	2	2
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	2	3	5
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	3	3	6
Spike glycoprotein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	1	4
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	2	0	2
DNA ligase A	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	3	4
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	11	0	11
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	4	0	6
Solute carrier family 22 member 2	0	6	0	10
Solute carrier family 22 member 2	0	3	0	4
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	3	0	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	3	0	5
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	10	0	10
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	8	0	12
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	8	0	10
Beta-2 adrenergic receptor	0	3	1	4
Beta-1 adrenergic receptor	0	3	1	5
Dipeptidase 1	0	1	0	1
Beta-3 adrenergic receptor	0	2	1	3
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	3	0	5
DNA gyrase subunit A	0	7	0	11
DNA gyrase subunit B	0	7	0	11
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	4	0	6
DNA topoisomerase 2-alpha	0	1	1	8
DNA gyrase subunit A	0	3	0	5
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	5	0	7
DNA gyrase subunit A	0	7	0	9
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	3	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Solute carrier organic anion transporter family member 1B1	0	7	0	9
DNA repair and recombination protein RAD54-like isoform 1	0	0	0	1
twin arginine protein translocation system - TatA protein	0	0	0	2
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	6	0	7
Stromelysin-1	0	8	1	9
Matrix metalloproteinase-9	0	6	0	6
Macrophage metalloelastase	0	1	0	1
GALC protein	4	0	0	4
Solute carrier family 22 member 3	0	4	0	4
Solute carrier family 22 member 3	0	1	0	2
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	4	2	7
Solute carrier organic anion transporter family member 1A1	0	5	0	5
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Multidrug and toxin extrusion protein 1	0	10	0	10
Chain A, Homo sapiens cyclin-dependent kinase 2	0	1	0	1
Chain C, Cell division protein kinase 2	0	1	0	1
Chain C, Cell division protein kinase 2	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
[Tau protein] kinase	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
Bone morphogenetic protein receptor type-1B	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	1	2	3
Serine/threonine-protein kinase RIO3	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	1	2	3
Cyclin-G-associated kinase	0	1	2	3
Serine/threonine-protein kinase DCLK1	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Dual specificity protein kinase CLK2	0	1	0	1
Dual specificity protein kinase CLK3	0	1	0	1
Dual specificity protein kinase CLK4	0	1	0	1
Death-associated protein kinase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	1	2	3
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 3	0	1	0	1
NUAK family SNF1-like kinase 1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Cyclin-T1	0	2	0	2
Tyrosine-protein kinase JAK2	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	2	2	4
Cyclin-dependent kinase 14	0	0	2	3
G2/mitotic-specific cyclin-B2	0	1	0	2
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	1	2	3
G1/S-specific cyclin-E2	0	2	0	2
cGMP-dependent protein kinase 1	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
Tyrosine-protein kinase ABL1	0	1	2	3
RAF proto-oncogene serine/threonine-protein kinase	0	1	2	3
Vitamin K-dependent protein C	0	1	0	1
High affinity nerve growth factor receptor	0	0	2	2
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	2	1	3
Insulin receptor	0	0	2	2
Tyrosine-protein kinase Lck	0	1	2	3
Cyclin-dependent kinase 1	0	2	1	5
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	0	2	2
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Platelet-derived growth factor receptor beta	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	0	2	2
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	2	2
Fibroblast growth factor receptor 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Cyclin-dependent kinase 4	0	2	2	5
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	2	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Insulin receptor-related protein	0	0	2	2
G2/mitotic-specific cyclin-B1	0	2	0	3
Serine/threonine-protein kinase B-raf	0	1	2	3
G2/mitotic-specific cyclin-B	0	1	0	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Platelet-derived growth factor receptor alpha	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	2	1	3
Synapsin-1	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	3	2	5
Vascular endothelial growth factor receptor 1	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Glycogen synthase kinase-3 beta	0	1	0	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Cyclin-A2	0	3	1	4
Cyclin-dependent kinase 11B	0	0	2	3
Ephrin type-A receptor 1	0	0	2	2
Fibroblast growth factor receptor 2	0	0	2	2
Multifunctional protein ADE2	0	0	1	1
Fibroblast growth factor receptor 4	0	0	2	2
Dual specificity protein kinase CLK1	0	1	0	1
Fibroblast growth factor receptor 3	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	3	1	4
cAMP-dependent protein kinase catalytic subunit beta	0	3	2	5
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
G1/S-specific cyclin-D1	0	2	0	2
Protein kinase C eta type	0	2	2	4
Cyclin-C	0	1	0	1
G1/S-specific cyclin-E1	0	2	0	2
Cyclin-dependent kinase 2	0	4	3	8
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	1	2	3
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	1	2	3
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	1	2	3
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
G1/S-specific cyclin-D3	0	1	0	1
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	2	2
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	1	2	3
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	0	2	2
Vascular endothelial growth factor receptor 2	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	1	2	3
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	1	2	3
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	2	2	4
Exosome RNA helicase MTR4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase TXK	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
Tyrosine-protein kinase ZAP-70	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	1	2	3
Mitogen-activated protein kinase 9	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	1	2	4
Casein kinase I isoform delta	0	2	2	5
MAP kinase-activated protein kinase 2	0	0	2	2
Cyclin-dependent kinase 8	0	1	2	4
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	2	2	4
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	1	2	3
Glycogen synthase kinase-3 beta	0	2	3	5
Cyclin-dependent kinase 7	0	1	2	4
Cyclin-dependent kinase 9	0	2	2	5
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Cyclin-H	0	1	0	1
CDK-activating kinase assembly factor MAT1	0	1	0	1
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Tyrosine-protein kinase JAK3	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
Death-associated protein kinase 1	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 12	0	2	3	5
Mitogen-activated protein kinase 10	0	3	2	5
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	3
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	2	2
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Tubulin alpha-1A chain	0	0	2	2
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	1	2	3
Cyclin-A1	0	3	1	4
Mitogen-activated protein kinase kinase kinase 9	0	1	2	3
Casein kinase I isoform alpha	0	1	0	1
Cyclin-dependent kinase 3	0	0	2	3
Cyclin-dependent kinase 6	0	1	1	3
Cyclin-dependent-like kinase 5	0	1	2	4
Cyclin-dependent kinase 16	0	0	2	3
Cyclin-dependent kinase 17	0	0	2	3
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	1	3
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C epsilon type	0	2	2	4
Cyclin-dependent-like kinase 5	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	2	3
Squalene synthase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 10	0	1	2	3
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	2	2	4
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C zeta type	0	2	1	3
Protein kinase C delta type	0	2	2	4
Tyrosine-protein kinase BTK	0	0	2	2
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	3
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Tyrosine-protein kinase ITK/TSK	0	0	2	2
Myotonin-protein kinase	0	1	2	3
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	3
Serine/threonine-protein kinase PAK 1	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	1	2	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	2	3
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	3
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Cyclin-dependent kinase 10	0	0	1	2
Serine/threonine-protein kinase D1	0	2	2	4
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	2	2
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	2	3	5
Serine/threonine-protein kinase STK11	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	4	3	7
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	1	2	3
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	2	0	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Myosin light chain kinase family member 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	2	2
Serine/threonine-protein kinase BRSK2	0	0	2	2
Cyclin-dependent kinase 20	0	0	0	1
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	2	2
G2/mitotic-specific cyclin-B3	0	1	0	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
Cyclin-dependent kinase 15	0	0	1	2
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	3
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	2	2
Cyclin-dependent kinase 1	0	1	0	1
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Serine/threonine-protein kinase PLK3	0	0	2	2
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
Casein kinase I isoform gamma-1	0	1	2	3
Serine/threonine-protein kinase PAK 6	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	1	2	3
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	1	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	2	2
eIF-2-alpha kinase GCN2	0	0	2	2
Serine/threonine-protein kinase NLK	0	1	2	3
Serine/threonine-protein kinase 17A	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	1	1
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	1	2	3
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	2	2
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	2	3
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	1	2	3
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
glp-1 receptor, partial	13	0	0	13
thioredoxin glutathione reductase	9	0	0	9
PINK1	2	0	0	2
neutrophil cytosol factor 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 3	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Rap guanine nucleotide exchange factor 3	5	0	0	5
Estrogen receptor	0	8	1	9
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	1	3
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	5	0	5
Glutamate receptor ionotropic, NMDA 3B	0	5	0	5
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2D1	0	2	0	2
Cytochrome P450 2D26	0	2	0	2
Muscarinic acetylcholine receptor M2	0	1	0	1
Cytochrome P450 2D3	0	2	0	2
Taste receptor type 2 member 46	0	0	2	2
Glutamate receptor ionotropic, NMDA 1	0	5	0	5
Glutamate receptor ionotropic, NMDA 2A	0	5	0	5
Glutamate receptor ionotropic, NMDA 2B	0	5	0	5
Glutamate receptor ionotropic, NMDA 2C	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	5	1	6
Cytochrome P450 2D4	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	3	0	3
Aldo-keto reductase family 1 member B10	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Transient receptor potential cation channel subfamily A member 1	0	0	2	3
Dihydrofolate reductase	0	8	0	8
Cytochrome c oxidase subunit 2	0	2	0	2
Fatty acid-binding protein, liver	0	4	0	4
Transthyretin	0	0	1	4
Interleukin-8	0	3	0	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	3	1	4
Aldo-keto reductase family 1 member B1	0	4	0	4
UDP-glucuronosyltransferase 2B7	0	1	0	4
UDP-glucuronosyltransferase 1A4	0	1	0	2
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Prostaglandin G/H synthase 2	0	6	0	6
Prostaglandin G/H synthase 2	0	3	0	4
Prostaglandin G/H synthase 1	0	3	0	4
P2Y purinoceptor 12	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	2	0	3
UDP-glucuronosyltransferase 1A10	0	2	0	2
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 1A4	0	0	0	1
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Multidrug resistance-associated protein 1	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor 1	0	3	2	6
Glutamate receptor 3	0	3	2	6
Glutamate receptor 4	0	3	2	6
Glycine receptor subunit alpha-1	0	0	1	1
Cannabinoid receptor 1	0	2	0	2
Cannabinoid receptor 2	0	1	1	2
N-arachidonyl glycine receptor	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoglyceride lipase	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
glucocerebrosidase	5	0	0	5
lysosomal alpha-glucosidase preproprotein	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
UDP-glucuronosyltransferase 2B17	0	0	0	1
NS5	0	0	2	2
Glucose transporter	0	1	0	1
Serine hydrolase RBBP9	0	1	0	1
Hexose transporter 1	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
60 kDa chaperonin	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Lanosterol 14-alpha demethylase	0	3	0	3
Luciferin 4-monooxygenase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Nuclear factor NF-kappa-B p105 subunit	0	0	0	1
Tyrosine-protein phosphatase 1	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	2	0	2
Caspase-7	4	0	0	4
caspase-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Sodium-dependent noradrenaline transporter	0	2	0	2
Potassium channel subfamily K member 2	0	3	0	3
Albumin	0	0	3	3
Angiotensin-converting enzyme	0	2	0	2
Dipeptidyl peptidase 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Alpha-2B adrenergic receptor	0	6	1	7
Acetylcholinesterase	0	1	0	1
Alpha-2C adrenergic receptor	0	6	1	7
Alpha-2A adrenergic receptor	0	6	1	7
Alpha-1D adrenergic receptor	0	8	0	8
Sodium-dependent dopamine transporter	0	7	0	7
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	4
D(2) dopamine receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	0	4
Sigma intracellular receptor 2	0	3	0	3
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
Transporter	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Beta-2 adrenergic receptor	0	1	2	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	3	0	3
Thymidylate synthase	0	1	0	2
Dihydrofolate reductase	0	2	1	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Advanced glycosylation end product-specific receptor	0	1	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	1	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
alpha synuclein, partial	1	0	0	1
luciferase	1	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
histone deacetylase 9 isoform 3	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Glutamate receptor ionotropic, kainate 1	1	3	1	6
Alpha-1D adrenergic receptor	0	3	1	4
Glutamate receptor ionotropic, kainate 2	1	3	1	6
Glutamate receptor ionotropic, kainate 3	1	3	0	5
Fatty-acid amide hydrolase 1	1	4	0	5
Glutamate receptor ionotropic, kainate 4	1	3	0	5
Leukotriene B4 receptor 1	1	0	0	1
Glutamate receptor ionotropic, kainate 5	1	3	0	5
Leukotriene B4 receptor 2	1	0	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Excitatory amino acid transporter 4	0	1	0	1
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	2	2
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	2
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	3	0	3
Acid-sensing ion channel 3	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Albumin	0	1	1	2
Cholinesterase	0	6	0	6
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	2	0	3
Adenosine receptor A2a	0	3	0	4
Substance-P receptor	0	4	0	4
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Snq2p	0	0	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	4
D(2) dopamine receptor	0	1	0	1
Envelope glycoprotein	0	0	1	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Heat shock protein HSP 90-alpha	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	2	1	4
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Phospholipase A2, major isoenzyme	0	1	0	1
Androgen receptor	0	5	2	7
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Thromboxane-A synthase	0	3	0	3
Serum paraoxonase/arylesterase 1	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Peptidylglycine alpha-amidating monooxygenase	0	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	4	0	4
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
NPYLR7B	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	2
Beta-2 adrenergic receptor	0	2	2	5
Beta-2 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Mitogen-activated protein kinase 13	0	2	2	4
Aryl hydrocarbon receptor	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	2	1	3
Histamine H3 receptor	0	0	1	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Renin	0	1	0	1
inositol monophosphatase 1	1	0	0	1
Cholecystokinin receptor type A	1	0	0	1
Gastrin/cholecystokinin type B receptor	1	0	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Delta-type opioid receptor	0	2	0	2
C-C chemokine receptor type 5	0	1	2	4
C-C chemokine receptor type 5	0	1	0	1
C-C chemokine receptor type 5	0	1	0	1
ClpP	2	0	0	2
DNA polymerase III, partial	1	0	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Cytochrome P450 1A2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Dipeptidyl peptidase 4	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Matrilysin	0	4	0	4
Multidrug transporter MdfA	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	3	0	3
Zinc finger protein mex-5	0	0	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Formyl peptide receptor-related sequence 1	0	0	1	1
fMet-Leu-Phe receptor	0	2	2	4
N-formyl peptide receptor 2	0	0	2	2
FML2_HUMAN	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
5-hydroxytryptamine receptor 1B	0	3	1	4
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Neutrophil elastase	0	3	0	3
Collagenase 3	0	7	0	8
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Bile acid receptor	0	1	0	1
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	2	0	2
Nitric oxide synthase, brain	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
MecA	0	1	0	1
Vpr	3	0	0	3
Valosin-containing protein	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Beta-lactamase 1	0	0	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Tumor necrosis factor	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
Retinoid isomerohydrolase	0	1	0	1
Retinoid isomerohydrolase	0	1	0	1
Retinoid isomerohydrolase	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Complement C1s subcomponent	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	3	1	4
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	2	0	2
Pannexin-1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	5	0	5
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Delta-type opioid receptor	0	3	0	3
Collagenase 3	0	2	0	2
Interstitial collagenase	0	4	0	5
Neutrophil collagenase	0	4	0	4
Matrix metalloproteinase-14	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	0	1	0	1
Kynurenine 3-monooxygenase	0	1	0	1
Kynurenine 3-monooxygenase	0	2	0	2
Kynurenine 3-monooxygenase	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Chain A, MMP-13	0	1	0	1
Chain A, MMP-13	0	1	0	1
Chain A, MMP-1	0	1	0	1
Stromelysin-2	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Erk2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Mitogen-activated protein kinase 2	0	1	0	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Protein kinase C gamma type	0	2	0	2
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Tyrosinase	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
Serine/threonine-protein kinase MAK	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 14	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
P2X purinoceptor 7	0	1	0	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
P2X purinoceptor 7	0	1	0	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Pyruvate kinase PKM	0	0	1	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
eyes absent homolog 2 isoform a	1	0	0	1
B2 bradykinin receptor	0	1	0	1
Beta-lactamase	0	2	0	2
Zinc finger protein GLI1	0	1	0	1
Zinc finger protein GLI2	0	1	0	1
Malate dehydrogenase	0	1	0	1
Chymotrypsinogen B	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Beta-lactamase	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	2	0	2
exodeoxyribonuclease V subunit RecB	0	2	0	2
exodeoxyribonuclease V subunit RecC	0	2	0	2
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	2	0	2
Dihydrofolate reductase	0	3	0	4
Protease	0	2	1	3
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	3
Protein argonaute-2	0	0	1	1
Transcriptional activator protein LasR	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 3	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Adenosine deaminase	0	0	0	1
RNA-directed RNA polymerase	0	1	1	2
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (995)

Protein Targets (2,021)

Meningitis, Pneumococcal

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (995)

Drugs Studied (334)

Protein Targets (2,021)