An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
| Member | Definition | Class |
|---|
| 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine | A racemate comprising equimolar amounts of (R)- and (S)-crizotinib. The active (R)-enantiomer acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer. | 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine; rac-crizotinib |
| 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide | A member of the class of benzamides that is 4-(imidazol-2-yl)benzamide carrying additional 1,3-benzodioxol-5-yl and pyridin-2-yl substituents at positions 4 and 5 respectively on the imidazole ring. | SB 431542 |
| abt 869 | A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 2-fluoro-5-methylphenyl group, while the other is substituted by a p-(3-amino-1H-indazol-4-yl)phenyl group. It is a potent, selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinases. | linifanib |
| aee 788 | A 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine which adopts an R-configuration. It is a potent inhibitor of human EGFR, VEGFR and HER2 receptor tyrosine kinases and exhibits anticancer and antiangiogenic activity. | AEE788 |
| alectinib | An organic heterotetracyclic compound that is 6,6-dimethyl-5,6-dihydro-11H-benzo[b]carbazol-11-one carrying additional cyano, 4-(morpholin-4-yl)piperidin-1-yl and ethyl substituents at positions 3, 8 and 9 respectively. Used (as the hydrochloride salt) for the treatment of patients with anaplastic lymphoma kinase-positive, metastatic non-small cell lung cancer. | alectinib |
| asp3026 | A member of the class of diamino-1,3,5-triazines that is 1,3,5-triazine-2,4-diamine in which the amino groups at positions 2 and 4 are respectively carrying 2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl and 2-(propan-2-ylsulfonyl)phenyl substituents. It is a potent inhibitor of anaplastic lymphoma kinase (ALK), Ack and ROS1 activity (IC50 values are 3.5, 5.8 and 8.9 nM respectively) and exhibits anti-cancer properties. | ASP-3026 |
| azd 8931 | A member of the class of quinazolines that is 4-amino-7-methoxyquinazoline in which the amino group has been substituted by a 3-chloro-2-fluorophenyl group and in which position 6 of the quinoline ring has been substituted by a {1-[2-(methylamino)-2-oxoethyl]piperidin-4-yl}oxy group. Sapitinib is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3. | sapitinib |
| AZD3463 | A member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. | AZD3463 |
| bms 754807 | A pyrrolotriazine that is pyrrolo[2,1-f][1,2,4]triazine which is substituted at position 2 by the pyrrolidine nitrogen of (2S)-N-(6-fluoropyridin-3-yl)-2-methylprolinamide, and at position 4 by a (5-cyclopropyl-1H-pyrazol-3-yl)amino group. It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases. | BMS-754807 |
| brivanib | A secondary alcohol resulting from the hydrolysis of the carboxylic ester group of brivanib alaninate. It is a dual VEGFR-2/FGFR-1 kinase inhibitor whose alanine prodrug, brivanib alaninate is currently under development as an oral agent for the treatment of cancer. | (2R)-1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methyl-6-pyrrolo[2,1-f][1,2,4]triazinyl]oxy]-2-propanol; brivanib |
| ceritinib | A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonyl)phenyl substituents. Used for the treatment of ALK-positive metastatic non-small cell lung cancer. | ceritinib |
| cl 387785 | A member of the class of quinazolines that is 4,6-diaminoquinazoine in which the one of the hydrogens attached to the amino group at position 4 has been replaced by a m-bromophenyl group while one of the hydrogens attached to the amino group at position 6 has been replaced by a but-2-ynoyl group. | N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide |
| cp 724714 | A 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity. | CP-724714 |
| crenolanib | A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a 8-(4-aminopiperidin-1-yl)quinolin-2-yl group at position 1 and by a (3-methyloxetan-3-yl)methoxy group at position 5. It is an inhibitor of type III tyrosine kinases, PDGFRalpha/beta and FLT3 (IC50 of 11, 3.2, and 4 nM). Currently under clinical development for the treatment of acute myeloid leukemia. | crenolanib |
| crizotinib | A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) | crizotinib |
| DDR1-IN-1 | A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzoic acid with the amino group of 5-(5-amino-2-methylphenoxy)-1,3-dihydro-2H-indol-2-one. It is a potent inhibitor of discoidin domain receptor tyrosine kinase 1 and 2 (DDR1/2) with IC50 = 105 nM and 413 nM, respectively. | DDR1-IN-1 |
| ebselen | A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. | ebselen |
| entrectinib | A member of the class of indazoles that is 1H-indazole substituted by [4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzoyl]amino and 3,5-difluorobenzyl groups at positions 3 and 5, respectively. It is a potent inhibitor of TRKA, TRKB, TRKC, ROS1, and ALK (IC50 values of 0.1 to 1.7 nM), and used for the treatment of NTRK, ROS1 and ALK gene fusion-positive solid tumours. | entrectinib |
| gilteritinib | A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. | gilteritinib |
| ki11502 | A member of the class of quinolines that acts as a receptor tyrosine kinase inhibitor and apoptosis inducer with potential for use in treatment of leukemia and colorectal cancer. | Ki11502 |
| lenvatinib | A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine. | lenvatinib |
| methyl 2,5-dihydroxycinnamate | A cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. | 2,5-dihydroxycinnamic acid methyl ester |
| muromonab-cd3 | An organic heteropentacyclic compound that is isolated from the marine sponge Xestospongia exigua. | xestospongin C |
| orantinib | An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. | orantinib |
| pd 153035 | A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7. | PD-153035 |
| pd 158780 | A pyridopyrimidine that is pyrido[3,4-d]pyrimidine-4,6-diamine in which the amino groups at positions 4 and 6 are substituted by a m-bromophenyl group and a methyl group, respectively. It is a potent, cell-permeable, reversible ATP-competitive inhibitor of EGFR tyrosine kinase activity [IC50 values of 0.008, 49 and 52 nM for EGFR, ErbB2 (HER2) and Erb4 (HER4)]. It does not inhibit FGF or PDGF-mediated tyrosine phosphorylation. Induces G1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells. | PD158780 |
| pd 166866 | A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by an amino group at position 2, 3,5-dimethoxyphenyl group at position 6, and by a (tert-butylcarbamoyl)nitrilo group at position 7. It is a selective ATP competitive inhibitor of the human fibroblast growth factor-1 receptor (FGFR1) tyrosine kinase with an IC50 of 52.4 nM. | PD-166866 |
| pd 173074 | A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N(3) is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor. | PD173074 |
| PDGF receptor tyrosine kinase inhibitor III | An N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a (4-phenoxyphenyl)aminocarbonyl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a 6,7-dimethoxyquinazolin-4-yl group. It is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT. | PDGF receptor tyrosine kinase inhibitor III |
| pexidartinib | A pyrrolopyridine that is 5-chloro-1H-pyrrolo[2,3-b]pyridine which is substituted by a [6-({[6-(trifluoromethyl)pyridin-3-yl]methyl}amino)pyridin-3-yl]methyl group at position 3. It is a potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, KIT, and FLT3 (IC50 of 20 nM, 10 nM and 160 nM, respectively). Approved by the FDA for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT). | pexidartinib |
| pf-06463922 | A cyclic ether that is 16,17-dihydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one substituted by methyl groups at positions 2 and 10R, and by cyano, amino and fluoro groups at positions 3, 7 and 12 respectively. It is a small molecule inhibitor of ALK and ROS1 kinase developed by Pfizer for the treatment of ALK-positive non-small cell lung cancer. | lorlatinib |
| ptk 787 | A succinate salt obtained by combining vatalanib with one molar equivalent of succinic acid. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit. | vatalanib succinate |
| quizartinib | A member of the class of phenylureas that is urea in which one of the amino groups has been substituted by a 5-tert-butyl-1,2-oxazol-3-yl group while the other has been substituted by a phenyl group substituted at the para- position by an imidazo[2,1-b][1,3]benzothiazol-2-yl group that, in turn, is substituted at position 7 by a 2-(morpholin-4-yl)ethoxy group. | quizartinib |
| semaxinib | An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is replaced by a 3,5-dimethylpyrrol-2-yl group. | semaxanib |
| su 11248 | | sunitinib |
| su 11652 | A member of the class of pyrrolecarboxamides obtained by formal condensation of the carboxy group of 5-[(Z)-(5-chloro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic acid with the primary amino group of N(1),N(1)-diethylethane-1,2-diamine. | SU11652 |
| tandutinib | An N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a 6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a (p-isopropoxyphenyl)aminocarbonyl group. Tandutinib is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT. | tandutinib |
| vatalanib | A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit. | vatalanib |
| zm 252868 | A hydrochloride obtained by combining PD-153035 with one equivalent of hydrochloric acid. | PD-153035 hydrochloride |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 9.2938 | 1 | 4 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.2306 | 1 | 2 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 7.5686 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 11.9837 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 16.1980 | 3 | 3 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 13.2532 | 2 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 12.0693 | 1 | 7 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 32.1841 | 3 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 4.4780 | 1 | 3 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 25.3995 | 8 | 16 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 10.2426 | 2 | 8 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 22.7172 | 2 | 2 |
| Ataxin-2 | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 5.8353 | 3 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 6.7456 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 26.1216 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 2.5119 | 2 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 1.4125 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 32.6619 | 2 | 5 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 12.6801 | 1 | 5 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 44.7322 | 2 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 24.0682 | 2 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 12.5893 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 7.0648 | 2 | 6 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 8.9125 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 11.8110 | 1 | 4 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 19.8146 | 3 | 7 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 8.6180 | 1 | 11 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 7.0648 | 2 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 15.1379 | 2 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 1.5545 | 1 | 4 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 0.4925 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 8.6991 | 1 | 12 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 16.5954 | 1 | 10 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 8.3973 | 1 | 4 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 11.0280 | 2 | 8 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.0683 | 2 | 15 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 12.9717 | 1 | 3 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 19.1180 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 20.6968 | 3 | 4 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 14.5974 | 3 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 4.7444 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 34.4174 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 14.1872 | 1 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 20.3942 | 9 | 22 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 25.5689 | 3 | 4 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 22.1841 | 9 | 16 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 5.4837 | 1 | 9 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 9.5606 | 4 | 54 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 32.2632 | 3 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 2 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 22.3872 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 30.3885 | 1 | 10 |
| G | Vesicular stomatitis virus | Potency | 8.6991 | 1 | 12 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| GALC protein | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 11.0280 | 1 | 4 |
| geminin | Homo sapiens (human) | Potency | 15.4963 | 4 | 12 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 1.6695 | 2 | 6 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.9219 | 2 | 3 |
| GLS protein | Homo sapiens (human) | Potency | 12.7427 | 2 | 5 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 29.6500 | 1 | 5 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 16.6288 | 3 | 5 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 29.8493 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 3.4972 | 2 | 17 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 8.6727 | 1 | 6 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 26.6032 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 43.8646 | 1 | 6 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 8.6991 | 1 | 12 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 11.1471 | 4 | 5 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 26.8325 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 17.5594 | 2 | 4 |
| IDH1 | Homo sapiens (human) | Potency | 19.7347 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 15.9541 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 8.6991 | 1 | 24 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 2.5119 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 12.0262 | 3 | 63 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 9.0114 | 1 | 3 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 5.6237 | 1 | 4 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 17.6453 | 4 | 8 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 18.0789 | 3 | 5 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 5.3162 | 1 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 6.7846 | 2 | 9 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 18.0120 | 2 | 3 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 11.2947 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 3.0809 | 1 | 3 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 29.2953 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 16.1426 | 2 | 6 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 21.8528 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 26.8325 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 20.9826 | 2 | 10 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 9.8828 | 3 | 8 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 125.8920 | 1 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 33.3326 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 19.3243 | 1 | 4 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 33.8078 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 19.6427 | 1 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 23.8023 | 3 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 34.1317 | 1 | 7 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.6104 | 1 | 3 |
| polyprotein | Zika virus | Potency | 30.3885 | 1 | 10 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 2.8371 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 6.8775 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 22.7327 | 1 | 4 |
| PPM1D protein | Homo sapiens (human) | Potency | 12.0277 | 1 | 32 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 20.6714 | 2 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 30.0474 | 1 | 2 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.5513 | 5 | 5 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 5.1189 | 4 | 4 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 84.2180 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 23.5062 | 2 | 5 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 12.7734 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 29.0144 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 15.4545 | 2 | 4 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 11.2541 | 3 | 4 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 13.3858 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Potency | 5.7988 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 16.9301 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 16.9301 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 19.1484 | 1 | 5 |
| snurportin-1 | Homo sapiens (human) | Potency | 15.9541 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 7.1812 | 2 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 8.1548 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.1139 | 2 | 20 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 44.6684 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 14.7324 | 2 | 5 |
| Thrombopoietin | Homo sapiens (human) | Potency | 3.1623 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 15.4593 | 2 | 8 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 39.8107 | 2 | 2 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 16.9330 | 1 | 1 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 55.0000 | 2 | 2 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 24.7028 | 1 | 2 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 42.8000 | 2 | 2 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 11.2349 | 2 | 11 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 16.4816 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.6104 | 1 | 3 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.6104 | 1 | 3 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 40.2433 | 2 | 7 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 26.0334 | 3 | 3 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 8.9060 | 1 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 29.8493 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 2.2555 | 2 | 2 |
| 1,25-dihydroxyvitamin D-3 receptor | Sus scrofa domesticus (domestic pig) | IC50 | 1.0400 | 1 | 1 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | IC50 | 0.1580 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | IC50 | 0.0617 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 28.0050 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 10.4350 | 2 | 2 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | IC50 | 0.0435 | 2 | 2 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Ki | 0.0170 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | GI50 | 0.2130 | 7 | 7 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 6.3697 | 189 | 255 |
| ALK tyrosine kinase receptor | Mus musculus (house mouse) | IC50 | 0.0800 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Ki | 0.2345 | 11 | 16 |
| Androgen receptor | Homo sapiens (human) | IC50 | 0.0020 | 1 | 1 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 1.7410 | 6 | 12 |
| Angiopoietin-1 receptor | Mus musculus (house mouse) | IC50 | 0.4480 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | IC50 | 0.0462 | 2 | 2 |
| Aromatase | Homo sapiens (human) | IC50 | 0.0384 | 2 | 7 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 1.5240 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 17.7000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 3.4760 | 6 | 7 |
| Aurora kinase A-interacting protein | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 1.0477 | 3 | 3 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | IC50 | 0.2055 | 11 | 11 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Ki | 0.0230 | 3 | 3 |
| Beta-adrenergic receptor kinase 1 | Bos taurus (cattle) | IC50 | 130.0000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 2.6060 | 5 | 5 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 21.9367 | 1 | 3 |
| Breakpoint cluster region protein | Homo sapiens (human) | GI50 | 20.0000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 3.1583 | 6 | 6 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 16.6667 | 3 | 3 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 20.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 20.0000 | 2 | 2 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.1336 | 2 | 3 |
| Cannabinoid receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 0.2000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 0.1327 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 0.0010 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 4.0400 | 1 | 1 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Chain A, Protein (fibroblast Growth Factor (fgf) Receptor 1) | Homo sapiens (human) | Ki | 0.0452 | 1 | 1 |
| Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | Homo sapiens (human) | IC50 | 0.1700 | 1 | 3 |
| Chain A, TGF-beta receptor type-1 | Homo sapiens (human) | Ki | 0.0170 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 10.4740 | 2 | 2 |
| Coiled-coil domain-containing protein 6 | Homo sapiens (human) | IC50 | 0.0100 | 1 | 1 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 31.9305 | 6 | 11 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | IC50 | 0.0240 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 60.8579 | 7 | 7 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Ki | 1.4850 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 4.7200 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | IC50 | 2.1580 | 3 | 3 |
| Cyclin-G-associated kinase | Homo sapiens (human) | IC50 | 0.1350 | 2 | 2 |
| Cyclin-H | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 30.0000 | 3 | 3 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 20.3333 | 3 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 24.3333 | 3 | 3 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 22.5005 | 4 | 4 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 16.5431 | 9 | 9 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 1.3000 | 1 | 2 |
| Dihydrofolate reductase | Mus musculus (house mouse) | IC50 | 1.3000 | 1 | 2 |
| Dihydrofolate reductase | Pneumocystis carinii | IC50 | 1.3000 | 1 | 2 |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 2 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | IC50 | 0.2590 | 1 | 2 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Echinoderm microtubule-associated protein-like 4 | Homo sapiens (human) | IC50 | 0.3576 | 21 | 42 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | IC50 | 10.1000 | 2 | 2 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Epidermal growth factor receptor | Homo sapiens (human) | GI50 | 0.8067 | 1 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 28.9064 | 121 | 160 |
| Epidermal growth factor receptor | Homo sapiens (human) | Ki | 0.1250 | 3 | 3 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | IC50 | 0.1772 | 3 | 4 |
| Eukaryotic elongation factor 2 kinase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Eukaryotic translation initiation factor 2-alpha kinase 3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 1.1500 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 13.4711 | 39 | 61 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | IC50 | 6.4902 | 14 | 14 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | IC50 | 7.4040 | 15 | 15 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | IC50 | 7.1616 | 13 | 13 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 0.5857 | 3 | 3 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Ki | 0.0170 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| G protein-coupled receptor kinase 5 | Homo sapiens (human) | IC50 | 0.8300 | 1 | 1 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | IC50 | 1.0350 | 1 | 1 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | Ki | 1.4850 | 1 | 1 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | IC50 | 1.0350 | 1 | 1 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 35.2393 | 2 | 6 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 0.7420 | 5 | 5 |
| Gastrin/cholecystokinin type B receptor | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 2 | 2 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 13.2000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 15.0867 | 3 | 3 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 0.0140 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 1.5353 | 46 | 51 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Ki | 0.0068 | 3 | 4 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.9009 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | IC50 | 0.2006 | 17 | 17 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Ki | 0.0240 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 2 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 3.4000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 6.5333 | 3 | 3 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 3.7000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 0.7300 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| HLA class II histocompatibility antigen gamma chain | Homo sapiens (human) | IC50 | 0.0021 | 1 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.0940 | 3 | 3 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | IC50 | 11.1562 | 16 | 17 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 33.3520 | 3 | 3 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 10.1212 | 13 | 14 |
| Insulin-like growth factor 1 receptor | Mus musculus (house mouse) | IC50 | 0.0130 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | IC50 | 0.2200 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | IC50 | 0.2200 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.2000 | 1 | 1 |
| Kinesin-1 heavy chain | Homo sapiens (human) | IC50 | 0.0100 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 13.9100 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0215 | 2 | 2 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | IC50 | 0.0015 | 2 | 2 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Ki | 0.0027 | 1 | 1 |
| Lysine--tRNA ligase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | IC50 | 0.5359 | 22 | 29 |
| Macrophage colony-stimulating factor 1 receptor | Mus musculus (house mouse) | IC50 | 0.0140 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 0.5700 | 2 | 2 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | IC50 | 5.1250 | 3 | 4 |
| Macrophage-stimulating protein receptor | Mus musculus (house mouse) | IC50 | 0.0800 | 1 | 1 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 1.1650 | 1 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 2.2400 | 1 | 1 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | GI50 | 0.1937 | 55 | 55 |
| Mast/stem cell growth factor receptor Kit | Mus musculus (house mouse) | GI50 | 0.0030 | 1 | 1 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | IC50 | 0.4226 | 37 | 45 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Ki | 0.0040 | 1 | 1 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | IC50 | 5.3800 | 2 | 2 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 2.4300 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 6.3000 | 1 | 1 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 6.3000 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 6.3000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 8.7667 | 3 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | IC50 | 0.8745 | 2 | 2 |
| MPI protein | Homo sapiens (human) | IC50 | 0.2905 | 2 | 2 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.1090 | 1 | 2 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 36.3000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 122.7000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.5000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.5000 | 1 | 1 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil cytosol factor 1 | Homo sapiens (human) | Ki | 125.0000 | 3 | 3 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | IC50 | 1.2690 | 1 | 1 |
| NT-3 growth factor receptor | Homo sapiens (human) | IC50 | 0.0100 | 8 | 8 |
| NT-3 growth factor receptor | Homo sapiens (human) | Ki | 0.0460 | 1 | 1 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 0.0480 | 1 | 1 |
| Nuclear receptor coactivator 4 | Homo sapiens (human) | IC50 | 0.0100 | 1 | 1 |
| Nucleophosmin | Homo sapiens (human) | IC50 | 0.0385 | 2 | 2 |
| perilipin-1 | Homo sapiens (human) | IC50 | 3.4100 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 1.1010 | 1 | 1 |
| Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | Homo sapiens (human) | IC50 | 5.5000 | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 13.0000 | 1 | 1 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | IC50 | 0.1110 | 1 | 1 |
| phosphomannomutase 2 | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | GI50 | 0.1939 | 4 | 4 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | IC50 | 0.8052 | 16 | 16 |
| Platelet-derived growth factor receptor alpha | Rattus norvegicus (Norway rat) | IC50 | 39.0000 | 3 | 3 |
| Platelet-derived growth factor receptor alpha | Mus musculus (house mouse) | IC50 | 7.3008 | 9 | 13 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | GI50 | 0.1140 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 10.5575 | 62 | 90 |
| Platelet-derived growth factor receptor beta | Mus musculus (house mouse) | IC50 | 12.7862 | 13 | 19 |
| Platelet-derived growth factor receptor beta | Rattus norvegicus (Norway rat) | IC50 | 39.0000 | 3 | 3 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Ki | 0.0080 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Potassium voltage-gated channel subfamily D member 3 | Homo sapiens (human) | IC50 | 50.1187 | 1 | 1 |
| Potassium voltage-gated channel subfamily E member 1 | Homo sapiens (human) | IC50 | 63.0957 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 15.4950 | 11 | 11 |
| Potassium voltage-gated channel subfamily KQT member 1 | Homo sapiens (human) | IC50 | 63.0957 | 1 | 1 |
| Potassium-transporting ATPase alpha chain 1 | Sus scrofa (pig) | IC50 | 0.0300 | 1 | 4 |
| Potassium-transporting ATPase subunit beta | Sus scrofa (pig) | IC50 | 0.0300 | 1 | 3 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2.1000 | 1 | 1 |
| Protein DBF4 homolog A | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Protein delta homolog 1 | Homo sapiens (human) | Ki | 0.0063 | 1 | 1 |
| Protein kinase C alpha type | Bos taurus (cattle) | IC50 | 40.2872 | 1 | 5 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 51.6667 | 3 | 3 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 15.5000 | 2 | 2 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Ki | 0.0140 | 1 | 1 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | IC50 | 0.1950 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 0.7450 | 23 | 24 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Ki | 0.0015 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | IC50 | 0.3001 | 24 | 31 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Ki | 0.4988 | 6 | 16 |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | IC50 | 24.5927 | 6 | 6 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 23.7762 | 19 | 32 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 23.3333 | 3 | 3 |
| RAC-alpha serine/threonine-protein kinase | Mus musculus (house mouse) | IC50 | 0.0220 | 1 | 1 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 6.9383 | 22 | 23 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | IC50 | 0.0033 | 3 | 3 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | IC50 | 0.0210 | 3 | 3 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | GI50 | 0.2194 | 12 | 12 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 0.2994 | 95 | 121 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Ki | 0.0060 | 2 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 5.3350 | 2 | 2 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 1.2950 | 14 | 16 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6200 | 2 | 3 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | IC50 | 1.2700 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | IC50 | 0.1313 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | IC50 | 0.1839 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | IC50 | 11.6872 | 1 | 1 |
| Serine-protein kinase ATM | Homo sapiens (human) | IC50 | 17.6000 | 1 | 1 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | IC50 | 5.0386 | 2 | 2 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | IC50 | 0.0168 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 20.0000 | 2 | 2 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase LMTK3 | Homo sapiens (human) | IC50 | 3.9070 | 1 | 2 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 2 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | IC50 | 3.7128 | 3 | 3 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Ki | 12.4000 | 1 | 4 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Ki | 12.4000 | 1 | 4 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Ki | 12.4000 | 1 | 4 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Ki | 12.4000 | 1 | 4 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | IC50 | 0.2200 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | IC50 | 1.7333 | 1 | 3 |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Smoothened homolog | Homo sapiens (human) | Ki | 0.0876 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 27.8298 | 2 | 2 |
| Sodium-dependent phosphate transport protein 2B | Homo sapiens (human) | IC50 | 0.0256 | 1 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 6.1000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 0.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| SRSF protein kinase 1 | Homo sapiens (human) | IC50 | 0.1950 | 1 | 1 |
| Structural capsid protein | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0230 | 1 | 1 |
| TGF-beta receptor type-1 | Homo sapiens (human) | IC50 | 0.2587 | 11 | 11 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Ki | 0.0170 | 1 | 1 |
| TGF-beta receptor type-2 | Homo sapiens (human) | IC50 | 0.0660 | 1 | 1 |
| Toxin B | Clostridioides difficile | IC50 | 0.0172 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 5.2900 | 2 | 2 |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | IC50 | 0.8800 | 1 | 1 |
| Transcription factor ETV6 | Homo sapiens (human) | IC50 | 1.6292 | 2 | 2 |
| Translocator protein | Rattus norvegicus (Norway rat) | IC50 | 0.0390 | 1 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | IC50 | 40.0000 | 1 | 1 |
| Tubulin beta chain | Sus scrofa (pig) | IC50 | 40.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | GI50 | 20.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 6.7685 | 11 | 13 |
| Tyrosine-protein kinase ABL1 | Mus musculus (house mouse) | IC50 | 1.1590 | 1 | 1 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | IC50 | 6.6800 | 2 | 2 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | IC50 | 19.8000 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | IC50 | 0.0033 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Ki | 0.0033 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | IC50 | 0.0060 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Ki | 0.0060 | 1 | 1 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | IC50 | 170.6490 | 3 | 3 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | IC50 | 0.0530 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Ki | 0.0530 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | IC50 | 25.0950 | 2 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | IC50 | 1.4683 | 3 | 3 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | IC50 | 0.5858 | 4 | 5 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Ki | 0.5290 | 1 | 1 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 14.9072 | 4 | 4 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 56.6915 | 9 | 9 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | IC50 | 17.7153 | 3 | 3 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | IC50 | 5.0500 | 2 | 2 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 0.0690 | 15 | 15 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 2.0250 | 2 | 2 |
| Tyrosine-protein kinase transforming protein Abl | Abelson murine leukemia virus | IC50 | 40.2872 | 1 | 5 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 0.0153 | 2 | 2 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 13.4667 | 3 | 3 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 30.4725 | 4 | 4 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 30.4725 | 4 | 4 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Mus musculus (house mouse) | IC50 | 1.0400 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 0.3865 | 34 | 46 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Ki | 0.0310 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | GI50 | 0.0330 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Danio rerio (zebrafish) | IC50 | 0.2790 | 1 | 4 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 4.5652 | 155 | 208 |
| Vascular endothelial growth factor receptor 2 | Mus musculus (house mouse) | IC50 | 0.5645 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Ki | 0.0112 | 5 | 5 |
| Vascular endothelial growth factor receptor 2 | Mus musculus (house mouse) | Ki | 0.0280 | 1 | 1 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 0.4720 | 14 | 16 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Ki | 0.0170 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 104.1196 | 3 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 33.4000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 33.4000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 33.4000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | Kd | 8.7812 | 3 | 16 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 16.3717 | 6 | 37 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | Kd | 8.1417 | 3 | 16 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 25.4497 | 1 | 19 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 25.4620 | 1 | 19 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 28.5076 | 1 | 20 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 28.7111 | 1 | 19 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 16.9491 | 4 | 34 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 19.0028 | 4 | 36 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 20.3157 | 4 | 35 |
| Activin receptor type-2A | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 21.3514 | 4 | 37 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 28.5219 | 1 | 19 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 27.8592 | 1 | 14 |
| Adenosine kinase | Homo sapiens (human) | Kd | 28.4949 | 1 | 19 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 28.5226 | 1 | 20 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 28.5248 | 1 | 20 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | EC50 | 4.0904 | 9 | 9 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 11.3489 | 6 | 25 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 7.6006 | 3 | 16 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 4.6700 | 1 | 1 |
| Ankyrin repeat and protein kinase domain-containing protein 1 | Homo sapiens (human) | Kd | 7.6069 | 3 | 16 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 15.0755 | 8 | 39 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 13 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | EC50 | 0.0890 | 1 | 1 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 21.3514 | 4 | 37 |
| Atypical kinase COQ8B, mitochondrial | Homo sapiens (human) | Kd | 9.4438 | 3 | 16 |
| Aurora kinase A | Homo sapiens (human) | Kd | 15.2855 | 6 | 39 |
| Aurora kinase B | Homo sapiens (human) | Kd | 14.0168 | 4 | 35 |
| Aurora kinase C | Homo sapiens (human) | Kd | 4.4734 | 5 | 18 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Kd | 3.5917 | 3 | 16 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 16.2747 | 6 | 37 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 20.0035 | 4 | 35 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 19.2427 | 3 | 29 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 19.1405 | 4 | 35 |
| Breakpoint cluster region protein | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 25.6365 | 1 | 19 |
| Bromodomain-containing protein 7 | Homo sapiens (human) | Kd | 11.0000 | 1 | 1 |
| Bromodomain-containing protein 9 | Homo sapiens (human) | Kd | 17.0000 | 1 | 1 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | Kd | 8.7571 | 1 | 7 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | Kd | 7.7741 | 4 | 17 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 17.1541 | 5 | 37 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | Kd | 7.9359 | 4 | 17 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | Kd | 7.8018 | 4 | 17 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 11.8747 | 4 | 17 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Kd | 7.2767 | 5 | 18 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | Kd | 8.0824 | 4 | 17 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 17.0581 | 5 | 36 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 15.5433 | 7 | 41 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 17.6199 | 4 | 35 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 22.1706 | 3 | 34 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | Kd | 12.2222 | 4 | 18 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 21.3567 | 3 | 28 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | Kd | 8.2308 | 2 | 13 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 19.1968 | 4 | 36 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 19.4905 | 4 | 37 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 19.8963 | 4 | 37 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 18.5104 | 4 | 33 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 19.5463 | 4 | 36 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Kd | 8.1914 | 3 | 16 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 18.4303 | 4 | 35 |
| Cell division control protein 2 homolog | Plasmodium falciparum 3D7 | Kd | 10.0000 | 1 | 7 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 13 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 9 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 20.0445 | 4 | 37 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 28.6990 | 1 | 22 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Cyclin-dependent kinase 11A | Homo sapiens (human) | Kd | 8.3012 | 3 | 16 |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | Kd | 8.3350 | 3 | 16 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 24.2322 | 2 | 26 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | Kd | 8.1756 | 3 | 16 |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 17.2701 | 6 | 38 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 19.0141 | 4 | 34 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 10.8389 | 4 | 18 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | Kd | 7.6718 | 3 | 16 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 19.7258 | 5 | 36 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 18.8850 | 4 | 34 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 20.5928 | 3 | 34 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 18.3263 | 4 | 35 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Kd | 7.6053 | 4 | 17 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 20.1889 | 4 | 37 |
| Cyclin-dependent kinase-like 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Cyclin-dependent kinase-like 2 | Homo sapiens (human) | Kd | 6.0100 | 2 | 10 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 21.3043 | 3 | 23 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 19.9204 | 4 | 35 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 13.1617 | 8 | 39 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 28.6455 | 1 | 22 |
| Cytochrome P450 2D6 | Homo sapiens (human) | EC50 | 4.4400 | 1 | 1 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | Kd | 9.6000 | 3 | 16 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Death-associated protein kinase 1 | Homo sapiens (human) | Kd | 8.1475 | 3 | 16 |
| Death-associated protein kinase 2 | Homo sapiens (human) | Kd | 7.2994 | 5 | 18 |
| Death-associated protein kinase 3 | Homo sapiens (human) | Kd | 7.5319 | 6 | 24 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 28.5920 | 1 | 21 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 18.7239 | 5 | 38 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | Kd | 7.3929 | 1 | 7 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 18.7701 | 4 | 36 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 18.6808 | 4 | 36 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 20.4286 | 4 | 35 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 15.0318 | 4 | 22 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 17.6536 | 2 | 27 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 20.1971 | 4 | 36 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 16.4087 | 7 | 41 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 16.1079 | 7 | 38 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 15.6537 | 5 | 26 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 15.8316 | 7 | 34 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 17.2078 | 6 | 32 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 20.3053 | 4 | 34 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 10 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 21.5325 | 3 | 32 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 13.6619 | 4 | 21 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 7.5360 | 2 | 10 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Echinoderm microtubule-associated protein-like 4 | Homo sapiens (human) | EC50 | 1.5520 | 3 | 3 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | Kd | 8.1588 | 3 | 16 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 28.6358 | 1 | 20 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 28.3340 | 1 | 18 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 28.5935 | 1 | 21 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 18.5396 | 4 | 34 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 16.1606 | 5 | 38 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | Kd | 6.9062 | 3 | 16 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 20.2155 | 4 | 36 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 19.2009 | 5 | 37 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | Kd | 5.5821 | 4 | 17 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 16.7880 | 6 | 35 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | Kd | 9.3925 | 3 | 16 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | Kd | 6.3533 | 5 | 18 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 19.4939 | 5 | 36 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 20.2243 | 4 | 37 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 18.8007 | 5 | 37 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 18.2440 | 3 | 29 |
| Epidermal growth factor receptor | Homo sapiens (human) | EC50 | 1.8763 | 8 | 8 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 8.8149 | 31 | 189 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | EC50 | 0.0860 | 1 | 1 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 12.2779 | 7 | 38 |
| Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 25.0000 | 2 | 28 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 24.9377 | 2 | 22 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 18.8393 | 5 | 37 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Kd | 6.8267 | 5 | 18 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | EC50 | 0.0300 | 1 | 1 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Kd | 7.0267 | 7 | 33 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Kd | 8.9188 | 3 | 16 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 15.5067 | 6 | 37 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | Kd | 7.4480 | 2 | 10 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 28.1077 | 1 | 15 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | Kd | 4.1000 | 2 | 2 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 28.6298 | 1 | 21 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 28.6974 | 1 | 23 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 22 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 20.8571 | 4 | 35 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 21.5789 | 4 | 38 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 28.4610 | 1 | 19 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 13.3726 | 11 | 58 |
| hexokinase HKDC1 | Homo sapiens (human) | EC50 | 38.8000 | 1 | 1 |
| hexokinase-1 isoform HKI | Homo sapiens (human) | EC50 | 41.9000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 13.9804 | 7 | 39 |
| HLA class I histocompatibility antigen, A alpha chain | Homo sapiens (human) | Kd | 21.2000 | 1 | 1 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 9.0055 | 2 | 10 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | Kd | 8.0062 | 2 | 10 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 7.2382 | 2 | 10 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | Kd | 2.7406 | 2 | 10 |
| Hormonally up-regulated neu tumor-associated kinase | Homo sapiens (human) | Kd | 8.1000 | 2 | 10 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | Kd | 8.1040 | 2 | 10 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | Kd | 9.5500 | 2 | 10 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 17.3856 | 4 | 35 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Insulin receptor | Homo sapiens (human) | Kd | 16.9477 | 6 | 38 |
| Insulin receptor-related protein | Homo sapiens (human) | Kd | 6.8556 | 3 | 16 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 17.7090 | 5 | 36 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 28.5664 | 1 | 20 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | Kd | 7.6944 | 3 | 16 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 21.2716 | 3 | 31 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 15.7182 | 4 | 35 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 20.7241 | 2 | 26 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 11 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 8.5847 | 2 | 14 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Kd | 6.6570 | 3 | 16 |
| Leukotriene C4 synthase | Cavia porcellus (domestic guinea pig) | Kd | 8.7043 | 1 | 7 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 18.5369 | 4 | 36 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 18.6145 | 4 | 35 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 28.0139 | 1 | 15 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | Kd | 1.1132 | 7 | 20 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 21.2421 | 3 | 31 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 20.2795 | 4 | 36 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 10 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 20.5882 | 4 | 34 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 8.9813 | 3 | 16 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 7.0175 | 3 | 16 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 17.9071 | 5 | 36 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 19.4521 | 4 | 35 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 3.1486 | 29 | 150 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 18.7953 | 4 | 36 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | Kd | 9.7700 | 2 | 10 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 11 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 21.3514 | 4 | 37 |
| Microtubule-associated serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 8.0400 | 2 | 10 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 18.2384 | 3 | 20 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 19.9753 | 4 | 36 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 20.5820 | 4 | 35 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Kd | 9.5000 | 3 | 16 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 20.0062 | 4 | 35 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 19.0401 | 4 | 35 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| Mitogen-activated protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Mitogen-activated protein kinase 6 | Homo sapiens (human) | Kd | 9.6118 | 4 | 17 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 20.2850 | 4 | 36 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 20.2982 | 4 | 36 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 19.5364 | 4 | 36 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 21.8264 | 3 | 29 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 17.7332 | 4 | 35 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | Kd | 7.1814 | 1 | 7 |
| Mitogen-activated protein kinase kinase kinase 13 | Homo sapiens (human) | Kd | 7.0420 | 2 | 10 |
| Mitogen-activated protein kinase kinase kinase 15 | Homo sapiens (human) | Kd | 7.5400 | 2 | 10 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | Kd | 2.3564 | 2 | 10 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 20.1072 | 3 | 29 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 20.3455 | 4 | 36 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 21.1660 | 3 | 29 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 19.4525 | 5 | 36 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 21.8420 | 3 | 28 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 6.8986 | 2 | 10 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | Kd | 8.7625 | 3 | 16 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 16.2962 | 4 | 34 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 18.4362 | 3 | 29 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 16.3478 | 5 | 38 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 15.9285 | 4 | 35 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 13.9630 | 6 | 40 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 26.6881 | 1 | 17 |
| Mixed lineage kinase domain-like protein | Homo sapiens (human) | Kd | 0.2170 | 1 | 1 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 28.7095 | 1 | 19 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | Kd | 5.2325 | 3 | 16 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | Kd | 6.8367 | 5 | 18 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 23.8628 | 2 | 26 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | Kd | 8.1278 | 3 | 16 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | Kd | 8.3372 | 1 | 6 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 18.5365 | 5 | 40 |
| Myosin-10 | Homo sapiens (human) | Kd | 27.7506 | 1 | 13 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| Myosin-IIIa | Homo sapiens (human) | Kd | 9.5688 | 3 | 16 |
| Myosin-IIIb | Homo sapiens (human) | Kd | 8.5438 | 3 | 16 |
| Myotonin-protein kinase | Homo sapiens (human) | Kd | 9.4625 | 3 | 16 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 15.5456 | 4 | 35 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 17.3420 | 6 | 46 |
| NT-3 growth factor receptor | Homo sapiens (human) | Kd | 4.5564 | 3 | 16 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | Kd | 8.1340 | 3 | 16 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 20.0158 | 4 | 36 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 28.4215 | 1 | 19 |
| Nucleoside diphosphate kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 27.5006 | 1 | 12 |
| oxytocin receptor | Homo sapiens (human) | EC50 | 11.4680 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 12 |
| Peripheral plasma membrane protein CASK | Homo sapiens (human) | Kd | 8.5914 | 1 | 7 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 28.0181 | 1 | 15 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 28.6301 | 1 | 20 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 28.4214 | 1 | 19 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 14 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | Homo sapiens (human) | Kd | 8.7125 | 3 | 16 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Kd | 10.0000 | 21 | 109 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Homo sapiens (human) | Kd | 8.1323 | 3 | 16 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 24.6154 | 2 | 26 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 16.2508 | 6 | 38 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | Kd | 7.2309 | 5 | 18 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | Kd | 1.5137 | 7 | 20 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 8.8144 | 10 | 43 |
| Poly [ADP-ribose] polymerase tankyrase-2 | Homo sapiens (human) | Kd | 9.6333 | 1 | 3 |
| POsterior Segregation | Caenorhabditis elegans | EC50 | 300.0000 | 1 | 1 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Procathepsin L | Homo sapiens (human) | EC50 | 4.6700 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Kd | 8.0193 | 1 | 7 |
| Protein delta homolog 1 | Homo sapiens (human) | Kd | 6.7000 | 1 | 3 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 25.0692 | 3 | 23 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 21.1023 | 4 | 39 |
| Protein kinase C epsilon type | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Protein kinase C eta type | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 24.6154 | 2 | 26 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 18.4109 | 4 | 34 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 11 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 17.2132 | 4 | 36 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 17.6902 | 5 | 37 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 6.9045 | 15 | 75 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | EC50 | 0.0058 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Kd | 9.3753 | 3 | 16 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 19.1989 | 5 | 36 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 28.6283 | 1 | 20 |
| Putative nucleoside diphosphate kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 28.7379 | 1 | 19 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 28.6017 | 1 | 18 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 20.8571 | 4 | 35 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 20.2314 | 4 | 35 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 20.8571 | 4 | 35 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | Kd | 8.8286 | 4 | 17 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 5.3558 | 6 | 19 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 17.0127 | 4 | 36 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 24.7377 | 2 | 21 |
| Receptor-interacting serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 7.6300 | 2 | 10 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 4.1275 | 36 | 141 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 4.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 4.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 4.6700 | 2 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.6700 | 2 | 2 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 22.2283 | 3 | 29 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 22.3939 | 3 | 31 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | Kd | 8.0580 | 2 | 10 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | Kd | 8.0360 | 2 | 10 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 15.3802 | 7 | 52 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | Kd | 8.1964 | 8 | 34 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 18.4407 | 6 | 40 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 15.7707 | 7 | 51 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 15.5617 | 9 | 55 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 16.9657 | 7 | 53 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 21.5603 | 3 | 28 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 22.8236 | 1 | 19 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Septin-9 | Homo sapiens (human) | Kd | 28.6961 | 1 | 23 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 14.3365 | 5 | 37 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 18.1558 | 6 | 37 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | Kd | 7.2247 | 5 | 18 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | Kd | 7.2650 | 5 | 18 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 15.4853 | 4 | 30 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | Kd | 8.1794 | 3 | 16 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 17.6531 | 4 | 36 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 17.6373 | 4 | 35 |
| Serine/threonine-protein kinase 3 | Mus musculus (house mouse) | Kd | 0.1600 | 1 | 1 |
| Serine/threonine-protein kinase 32A | Homo sapiens (human) | Kd | 8.6629 | 1 | 7 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | Kd | 8.4025 | 3 | 16 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | Kd | 6.9282 | 3 | 16 |
| Serine/threonine-protein kinase 35 | Homo sapiens (human) | Kd | 6.3236 | 2 | 10 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 16.3012 | 3 | 16 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 16.5861 | 5 | 28 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 16.9913 | 6 | 38 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 11 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 18.1481 | 7 | 54 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | Kd | 8.7812 | 3 | 16 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | Kd | 8.3312 | 3 | 16 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 19.8431 | 4 | 37 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | Kd | 8.0017 | 2 | 10 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | Kd | 7.6200 | 3 | 16 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 17.7549 | 4 | 35 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 18.3414 | 4 | 37 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | Kd | 7.5900 | 3 | 16 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | Kd | 8.0294 | 3 | 16 |
| Serine/threonine-protein kinase DCLK3 | Homo sapiens (human) | Kd | 8.1456 | 3 | 16 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 22.6980 | 3 | 30 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 18.0465 | 4 | 37 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | Kd | 7.1738 | 3 | 16 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | Kd | 8.3500 | 3 | 16 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 18.2314 | 5 | 37 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 20.8571 | 4 | 35 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 20.5382 | 4 | 34 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 19.2084 | 4 | 35 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 19.5865 | 4 | 36 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 12 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 18.8576 | 6 | 39 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 23.8818 | 2 | 26 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 17.7857 | 4 | 28 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 19.7555 | 4 | 35 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | Kd | 7.6300 | 2 | 10 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 20.8571 | 4 | 35 |
| Serine/threonine-protein kinase OSR1 | Homo sapiens (human) | Kd | 8.1060 | 2 | 10 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 20.3030 | 4 | 33 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | Kd | 8.1280 | 3 | 16 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 19.9434 | 4 | 37 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Kd | 8.2450 | 3 | 16 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 16.2880 | 4 | 25 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 20.8571 | 4 | 35 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 18.1034 | 5 | 29 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | Kd | 8.5750 | 3 | 16 |
| Serine/threonine-protein kinase PknB | Mycobacterium tuberculosis H37Rv | Kd | 8.5839 | 1 | 7 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 18.1481 | 4 | 27 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Kd | 8.9400 | 2 | 10 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Kd | 9.8125 | 3 | 16 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 15.3645 | 6 | 37 |
| Serine/threonine-protein kinase PRP4 homolog | Homo sapiens (human) | Kd | 8.0780 | 2 | 10 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Serine/threonine-protein kinase RIO1 | Homo sapiens (human) | Kd | 7.8878 | 3 | 16 |
| Serine/threonine-protein kinase RIO2 | Homo sapiens (human) | Kd | 7.2998 | 3 | 11 |
| Serine/threonine-protein kinase RIO3 | Homo sapiens (human) | Kd | 8.4625 | 3 | 16 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | Kd | 7.3571 | 1 | 7 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | Kd | 7.4457 | 1 | 7 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | Kd | 8.7250 | 3 | 16 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 18.7187 | 4 | 36 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 22.5807 | 3 | 31 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 19.7092 | 4 | 34 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 20.1375 | 4 | 33 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 23.1920 | 2 | 26 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 21.7645 | 3 | 29 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 21.6914 | 3 | 31 |
| Serine/threonine-protein kinase TNNI3K | Homo sapiens (human) | Kd | 9.3819 | 3 | 16 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | Kd | 8.2638 | 3 | 16 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | Kd | 8.1869 | 3 | 16 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 20.4685 | 3 | 30 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | Kd | 7.1626 | 2 | 10 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 20.2729 | 3 | 29 |
| Serine/threonine-protein kinase ULK3 | Mus musculus (house mouse) | Kd | 0.1100 | 1 | 1 |
| Serine/threonine-protein kinase VRK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 20.8842 | 3 | 29 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | Kd | 8.6629 | 1 | 7 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 300.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 4.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.6700 | 1 | 1 |
| SRSF protein kinase 1 | Homo sapiens (human) | Kd | 7.6594 | 3 | 16 |
| SRSF protein kinase 2 | Homo sapiens (human) | Kd | 8.1606 | 3 | 16 |
| SRSF protein kinase 3 | Homo sapiens (human) | Kd | 7.8318 | 2 | 10 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 15.7048 | 6 | 38 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 28.5568 | 1 | 20 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | Kd | 8.0280 | 2 | 10 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 1.5190 | 1 | 1 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 28.3337 | 1 | 18 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 9.3062 | 3 | 16 |
| TGF-beta receptor type-1 | Homo sapiens (human) | EC50 | 0.1720 | 1 | 1 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 19.5618 | 4 | 35 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 21.3514 | 4 | 37 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 15.4707 | 6 | 36 |
| Transient receptor potential cation channel subfamily M member 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 7 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 4.6700 | 1 | 1 |
| Tubulin alpha-1A chain | Rattus norvegicus (Norway rat) | Kd | 8.3767 | 1 | 6 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 28.5956 | 1 | 19 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 7.9470 | 40 | 225 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 18.1571 | 5 | 37 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | Kd | 7.0191 | 3 | 16 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 19.7255 | 4 | 35 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 21.1111 | 4 | 36 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 15.3234 | 5 | 38 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 18.3674 | 4 | 38 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 12.1431 | 6 | 25 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 17.5109 | 4 | 35 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 18.8728 | 5 | 37 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 17.0396 | 5 | 36 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Kd | 7.6274 | 3 | 16 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 16.0206 | 8 | 47 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 11.8466 | 6 | 23 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | Kd | 7.7375 | 3 | 16 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 16.1415 | 5 | 36 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 17.4322 | 6 | 38 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 13.9717 | 4 | 24 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | Kd | 6.3581 | 3 | 16 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | Kd | 7.5592 | 3 | 16 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | Kd | 6.0634 | 3 | 16 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | Kd | 10.0000 | 3 | 16 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 20.6985 | 4 | 38 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 20.0293 | 4 | 35 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | Kd | 9.4281 | 3 | 16 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 16.7704 | 5 | 37 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | Kd | 9.6375 | 3 | 16 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 28.4938 | 1 | 19 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 23.3343 | 1 | 9 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 23.8272 | 1 | 19 |
| Uncharacterized serine/threonine-protein kinase SBK3 | Homo sapiens (human) | Kd | 7.4040 | 2 | 10 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Kd | 1.7674 | 5 | 18 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | EC50 | 0.2500 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 2.7506 | 7 | 22 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Kd | 2.7868 | 7 | 21 |
| vasopressin V1a receptor | Homo sapiens (human) | EC50 | 12.0700 | 1 | 1 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 21.0988 | 4 | 35 |
| Wee1-like protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 10 |
| Zinc finger protein mex-5 | Caenorhabditis elegans | EC50 | 300.0000 | 1 | 1 |