"Glioblastomas are among the most malignant tumours for which no curative treatment exists." | ( Bodmer, S; Fontana, A; Frei, K; Malipiero, U; Siepl, C, 1991) |
"Glioblastoma is the most malignant primary brain tumor." | ( Brem, H; Martuza, RL; Mineta, T; Ojeifo, J; Takamiya, Y, 1994) |
"Glioblastoma is one of the most malignant of all neoplasms, and often shows resistance to chemotherapy and radiation therapy." | ( Iida, T; Iwanaga, M; Kondo, T; Matsuo, T; Mori, K; Shibata, S; Urata, Y; Yasunaga, A, 1998) |
"Glioblastomas are particularly resistant to classical antitumor treatments." | ( Chambaut-Guérin, AM; Costa, SL; Fages, C; Gauthereau, X; Lefrançois, T; Tardy, M, 2000) |
"Glioblastomas are highly vascular malignant brain tumors that often overexpress vascular endothelial growth factor (VEGF)." | ( Lee, J; Maity, A; O'Rourke, DM; Pore, N; Solomon, D, 2000) |
"Two biopsies from glioblastomas are directly studied by (1)H-NMR without any treatment (ex vivo NMR)." | ( Bottura, G; Fini, G; Tinti, A; Tosi, MR; Trinchero, A; Tugnoli, V, 2001) |
"Glioblastomas are known to contain numerous genetic and physiological alterations affecting cell survival and proliferation; one of the most common alterations being platelet-derived growth factor (PDGF) autocrine signaling characterized by coexpression of PDGF and its receptor." | ( Giese, NA; Hollenbach, SJ; Israel, MA; Lokker, NA; Sullivan, CM, 2002) |
"Glioblastoma is a malignant tumor that occurs in the cerebrum during adulthood." | ( Hamasaki, O; Kuwabara, R; Minamoto, A; Mishima, HK; Nakahara, T; Okada, K; Sakamoto, I; Watanabe, W, 2002) |
"Glioblastoma is a life-threatening tumor in the human brain despite the fact that radio-chemotherapy inducing DNA damage has been improved in the last decade." | ( Houkin, K; Ichimiya, S; Kikuchi, T; Kondo, N; Momota, H; Sato, N; Torigoe, T; Yamaki, T, 2003) |
"The glioblastoma is the highest dedifferentiated form of astrocytic brain tumors, which is refractory to chemotherapy in most cases." | ( Harada, K; Rittierodt, M, 2003) |
"Glioblastoma is a lethal neoplasm resistant to conventional radiotherapy and chemotherapy." | ( Daniel, P; Frank, B; Gillissen, B; Naumann, U; Schmidt, F; Weit, S; Weller, M; Wick, W, 2003) |
"Glioblastoma is a therapeutic challenge as a highly infiltrative, proliferative, and resistant tumor." | ( Andre, P; Christov, C; de Boüard, S; Guillamo, JS; Jouault, H; Laurent, N; Lotteau, V; Peschanski, M; Zini, R, 2004) |
"Glioblastoma is the highest dedifferentiated form of astrocytic brain tumors, and it is refractory to chemotherapy in most cases." | ( Harada, K; Rittierodt, M; Tschernig, T, 2004) |
"Glioblastoma is one of the most radioresistant tumors." | ( Hong, SI; Jung, KY; Kim, DW; Kim, MS; Lee, HC; Lee, SH; Park, IC; Park, MJ; Rhee, CH; Woo, SH; Yoo, H, 2004) |
"Glioblastoma is the deadliest and most prevalent brain tumor." | ( Banik, NL; Das, A; Patel, SJ; Ray, SK, 2004) |
"Human glioblastoma is a deadly brain tumor that is often treated with a combination of drugs." | ( Banik, NL; Patel, SJ; Ray, SK; Sribnick, EA; Sur, P, 2005) |
"Glioblastoma is a highly angiogenic tumor with a dismal prognosis." | ( Dichgans, J; Herrlinger, U; Nägele, T; Rieger, J; Steinbach, JP; Weller, M, 2005) |
"Glioblastoma is a highly malignant brain tumor with a high-invasive phenotype, so the prognosis is unfavorable, even in response to multidisciplinary treatment strategies." | ( Bertelli, AA; Gagliano, N; Gioia, M; Magnani, I; Moscheni, C; Torri, C, 2005) |
"Glioblastomas are among the most difficult neoplasms to treat with continued poor prognosis for long-term survival." | ( Higashikubo, R; Jiang, Z; Lytle, RA; Rich, KM; Zheng, X, 2005) |
"Surgical cure of glioblastomas is virtually impossible and their clinical course is mainly determined by the biologic behavior of the tumor cells and their response to radiation and chemotherapy." | ( Beerenwinkel, N; Feiden, W; Hartmann, C; Ketter, R; Lengauer, T; Meese, E; Rahnenführer, J; Steudel, WI; Stockhammer, F; Strowitzki, M; Urbschat, S; von Deimling, A; Wemmert, S; Zang, KD, 2005) |
"Glioblastomas are the most frequent and the most aggressive primary brain tumors in adults." | ( Benouaich-Amiel, A; Delattre, JY; Simon, JM, 2005) |
"Glioblastoma is a highly malignant brain tumor with a highly invasive phenotype and hence an unfavorable prognosis even in response to multidisciplinary treatment strategies." | ( Bertelli, AA; Gagliano, N; Gioia, M; Magnani, I; Moscheni, C; Nowicky, W; Torri, C, 2006) |
"Glioblastomas are a rich source of immunosuppressive molecules which may interfere with immune recognition and rejection as well as clinical strategies of active immunotherapy." | ( Naumann, U; Weller, M; Wick, W, 2006) |
"Malignant glioblastoma is one of the most common malignant tumors in the neurological system." | ( Cao, WD; Cheng, G; Gao, DK; Jin, BQ; Tang, HF; Wang, XL; Zhang, X; Zhang, XH; Zhang, Y, 2006) |
"Glioblastomas are highly vascularized tumors and anti-angiogenic strategy is one of the most promising therapeutic approaches to treat brain tumors." | ( Groves, MD; Jeon, JW; Kang, CM; Kim, JH; Kim, JT; Kim, MH; Kim, YJ; Nam, DH; Park, K; Park, SY; Son, MJ; Song, HS, 2006) |
"Malignant glioblastoma is one of the most common malignant tumors in the neurological system." | ( Cao, WD; Cheng, G; Gao, DK; Tang, HF; Wang, XL; Zhang, X; Zhang, Y, 2006) |
"Glioblastomas are intrinsically resistant to conventional radiation therapy." | ( Gewirtz, DA; Quick, QA, 2006) |
"Glioblastoma is the most common and highly malignant brain tumor." | ( Banik, NL; Das, A; Hajiaghamohseni, LM; Haque, A; Ray, SK; Younger, A, 2007) |
"Because glioblastomas are highly invasive primary brain tumors that can originate from astrocytes, we explored the involvement of PEA-15 in the control of astrocyte migration." | ( Beuvon, F; Canton, B; Chneiweiss, H; De Bouard, S; Iturrioz, X; Junier, MP; Léonard, N; Mouhamad, S; Ramos, JW; Renault-Mihara, F; Sharif, A, 2006) |
"Glioblastomas are widely characterised by the mutation of the p53 gene and p53 disruption sensitizes glioblastoma cells to DNA topoisomerase I (TOPO I) inhibitor-mediated apoptosis." | ( Chianese, M; Cimmino, G; Laus, G; Penitente, R; Pepe, S; Prece, D; Quesada, P, 2007) |
"Glioblastomas are malignant brain tumors that are rarely curable, even with aggressive therapy (surgery, chemotherapy, and radiation)." | ( Cerniglia, GJ; Gupta, AK; Maity, A; Pore, N, 2006) |
"Glioblastoma is the most common primary brain tumour with poor overall survival." | ( Ng, WH; Too, HP; Wan, GQ, 2007) |
"Glioblastomas are the most malignant gliomas with median survival times of only 15 months despite modern therapies." | ( Hau, P; Hegi, ME; Stupp, R, 2007) |
"Glioblastoma is the most common astrocytic brain tumor in humans." | ( Banik, NL; Karmakar, S; Patel, SJ; Ray, SK, 2007) |
"Glioblastomas are high-risk primary brain tumors that are generally unresponsive or only weakly responsive to the currently available antineoplastic agents." | ( Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Jiang, H; Liu, Y, 2007) |
"Glioblastomas are treated by surgical resection followed by radiotherapy [X-ray therapy (XRT)] and the alkylating chemotherapeutic agent temozolomide." | ( Batchelor, TT; Betensky, RA; Cahill, DP; Codd, PJ; Curry, WT; Futreal, PA; Iafrate, AJ; Levine, KK; Louis, DN; Reavie, LB; Romany, CA; Stratton, MR, 2007) |
"Glioblastomas are malignant brain tumors that are very difficult to cure, even with aggressive therapy consisting of surgery, chemotherapy, and radiation." | ( Bernhard, EJ; Cerniglia, GJ; Georgescu, MM; Gupta, AK; Hahn, SM; Jiang, Z; Maity, A; Mick, R; Pore, N, 2007) |
"Glioblastoma is the most malignant human brain tumor that shows poor response to existing therapeutic agents." | ( Banik, NL; Karmakar, S; Ray, SK, 2007) |
"Glioblastoma is the deadliest brain tumor in humans." | ( Banik, NL; Karmakar, S; Ray, SK, 2007) |
"Glioblastoma is the most malignant and common type of brain tumor with devastating outcome." | ( Banik, NL; Haque, A; Ray, SK, 2007) |
"Glioblastoma is the deadliest and most prevalent brain tumor, which is not yet amenable to any treatments." | ( Banik, NL; Das, A; Ray, SK, 2007) |
"Glioblastoma is the most prevalent and highly malignant brain tumor that continues to defy current treatment strategies." | ( Banik, NL; Karmakar, S; Patel, SJ; Ray, SK, 2007) |
"Glioblastoma is a highly malignant tumor, characterized by an unfavorable prognosis even in response to multidisciplinary treatment strategies, owing to its high-invasive phenotype." | ( Costa, F; Donetti, E; Gagliano, N; Gioia, M; Magnani, I; Moscheni, C; Nowicky, W; Torri, C, 2007) |
"Glioblastomas are a type of malignant brain tumor and are among the most difficult cancers to treat." | ( Cunningham, C; Magro, AD; Magro, AM; Miller, MR, 2007) |
"Glioblastoma is the most malignant and prevalent brain tumor in humans." | ( Banik, NL; Janardhanan, R; Ray, SK, 2008) |
"Glioblastoma is the deadliest brain tumor that remains incurable." | ( Banik, NL; Das, A; Ray, SK, 2009) |
"Glioblastoma is both the most common and most aggressive primary brain tumor." | ( Chamberlain, MC; Mrugala, MM, 2008) |
"Glioblastomas are notorious for resistance to therapy, which has been attributed to DNA-repair proficiency, a multitude of deregulated molecular pathways, and, more recently, to the particular biologic behavior of tumor stem-like cells." | ( Cairncross, JG; de Tribolet, N; Delorenzi, M; Dietrich, PY; Domany, E; Gorlia, T; Hainfellner, JA; Hamou, MF; Hegi, ME; Heppner, FL; Janzer, RC; Kouwenhoven, MC; Lambiv, WL; Migliavacca, E; Murat, A; Regli, L; Shay, T; Stupp, R; Wick, W; Zimmer, Y, 2008) |
"As glioblastomas are characterized by high expression levels of anti-apoptotic Bcl-2 family proteins, we studied the effects of the novel Bcl-2 inhibitor, ABT-737, on malignant glioma cells." | ( Böck, BC; Campos, B; Farhadi, M; Fassl, A; Herold-Mende, C; Kraemer, A; Macher-Goeppinger, S; Radlwimmer, B; Roth, W; Tagscherer, KE; Wiestler, OD, 2008) |
"As glioblastoma are resistant to the cytotoxic effect of TNFalpha, we investigated the potential of Ebselen in sensitizing glioma cells to TNFalpha-induced apoptosis." | ( Joseph, C; Sen, E; Sharma, V; Sk, UH; Tewari, R, 2008) |
"Glioblastoma is a malignant astrocytic tumor with a median survival of about 12 months for which new therapeutic strategies are required." | ( Cambar, J; De Giorgi, F; Ichas, F; L'Azou, B; Passagne, I; Pédeboscq, S; Pometan, JP, 2008) |
"Glioblastoma is the most common central nervous system tumor, is associated with high morbidity and mortality, and responds poorly to surgical, chemical, and radiation therapy." | ( Eling, TE; Kamitani, H; Watanabe, T; Yoshioka, H, 2008) |
"Glioblastoma is the most malignant brain tumor in humans and an average survival of glioblastoma patients hardly exceeds 12 months." | ( Banik, NL; Ray, SK; Zhang, R, 2008) |
"Malignant glioblastoma is one of the highest proliferative and invasive tumors within the central nervous system (CNS); the therapeutical options for this disease are still very poor." | ( Limonta, P; Mai, S; Montagnani Marelli, M; Moretti, RM; Müller, O; Van Groeninghen, JC, 2009) |
"Glioblastoma is the most common and aggressive form of primary brain tumor." | ( de Groot, J; Milano, V, 2009) |
"Surgical removal of glioblastomas is challenging due to their infiltrative growth pattern." | ( Cadosch, D; Fournier, JY; Gautschi, OP; Hildebrandt, G; van Leyen, K, 2009) |
"Glioblastomas are known to invade outside the contrast-enhancing area." | ( Jensen, TR; Schmainda, KM, 2009) |
"Glioblastoma is a highly lethal neoplasm with a median survival of 12-14 months; only 2-5% of patients survive >3 years." | ( Inoue, T; Kanamori, M; Kumabe, T; Nakazato, Y; Sonoda, Y; Tominaga, T; Watanabe, M, 2009) |
"Human glioblastoma is a deadly brain cancer that continues to defy all current therapeutic strategies." | ( Banik, NL; Das, A; Ray, SK, 2010) |
"Glioblastoma is a highly vascularised tumour with a high expression of both vascular endothelial growth factor (VEGF) and VEGFR." | ( Brandes, AA; Gorlia, T; Hau, P; Kros, JM; Lacombe, D; Mirimanoff, RO; Stupp, R; Tosoni, A; van den Bent, MJ, 2010) |
"Glioblastoma are known to be highly resistant to chemotherapy." | ( Bonnet, D; Dontenwill, M; Leger, DY; Maglott, A; Martin, S; Martinkova, E; Stiborova, M; Takeda, K, 2010) |
"Glioblastoma is the most common type of primary brain tumor and is rapidly progressive with few treatment options." | ( Brown, C; Buettner, R; Hedvat, M; Jensen, M; Jove, R; Schroeder, A; Scuto, A; Starr, R; Yang, F, 2010) |
"Glioblastoma is an incurable solid tumor characterized by increased expression of vascular endothelial growth factor (VEGF)." | ( Ancukiewicz, M; Batchelor, TT; Benner, T; Chea, H; Cohen, KS; di Tomaso, E; Drappatz, J; Duda, DG; Eichler, AF; Exarhopoulos, A; Gerstner, E; Hochberg, FH; Ivy, P; Jain, RK; Loeffler, JS; Louis, DN; Moses, MA; Plotkin, SR; Sorensen, AG; Wen, PY, 2010) |
"Glioblastoma is the most common primary malignant brain tumor; however, glioblastoma in children is less common than in adults, and little is known about its clinical outcome in children." | ( Ahn, HS; Cho, BK; Kim, DG; Kim, IH; Kim, SK; Lee, JY; Park, SH; Phi, JH; Song, KS; Wang, KC, 2010) |
"The prognosis of glioblastoma is better in children than in adults." | ( Ahn, HS; Cho, BK; Kim, DG; Kim, IH; Kim, SK; Lee, JY; Park, SH; Phi, JH; Song, KS; Wang, KC, 2010) |
"Glioblastoma is the most common primary brain tumor, with typical histopathologic findings, pseudopalisading necrosis, and microvascular proliferation, all of which are associated with a poor prognosis." | ( Chi, SG; Chung, YG; Kang, SH; Park, DH; Park, KJ; Yu, MO, 2010) |
"Glioblastoma is one of the most frequent primary brain tumors and is characterized by aggressive clinical behavior and biologic heterogeneity." | ( Jung, S; Jung, TY; Kim, HS; Kim, KJ; Lee, KH; Lee, MC; Moon, KS, 2011) |
"Human malignant glioblastomas are highly invasive tumors." | ( Hibner, U; Kaminska, B; Kijewska, M; Kwiatkowska, A; Lipko, M, 2011) |
"Glioblastoma is the most common primary brain tumor with a dismal prognosis, highlighting the need for novel treatment strategies." | ( Bangert, A; Cristofanon, S; Debatin, KM; Fulda, S; Häcker, S, 2011) |
"Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain." | ( Bernreuther, C; Gelperina, S; Glatzel, M; Khalansky, AS; Kreuter, J; Maksimenko, O; Wohlfart, S, 2011) |
"Glioblastoma is the most malignant form of adult brain tumor and is associated with a dismal prognosis." | ( Cheng, J; Huang, H; Lin, H; Liu, B; Xiong, W; Zhang, W; Zhang, X; Zhang, Y, 2011) |
"Glioblastomas are highly lethal cancers for which conventional therapies provide only palliation." | ( Flavahan, WA; Heddleston, JM; Hitomi, M; Hjelmeland, AB; Kim, Y; Minhas, S; Rich, JN; Venere, M; Yang, K, 2011) |
"Delineation of glioblastoma is complex." | ( Guillevin, R; Noël, G, 2011) |
"Glioblastoma is the most malignant type of brain tumor." | ( Fukushima, T; Kataoka, H; Kawaguchi, M; Takeshima, H; Tanaka, H; Umezawa, K; Yorita, K, 2012) |
"Glioblastoma is a highly malignant brain tumor that relentlessly defies therapy." | ( Belden, CJ; Fadul, CE; Harris, BT; Israel, MA; Pastel, DA; Paulsen, K; Ran, C; Roberts, DW; Valdes, PA, 2011) |
"In most cases, glioblastoma are characterized by a constitutive activation of NF-κB." | ( Agostinis, P; Coupienne, I; Fettweis, G; Piette, J; Rubio, N, 2011) |
"Glioblastomas are invasive tumors with poor prognosis despite current therapies." | ( Agostino, NR; DiDomenico, JD; Jane, EP; Pollack, IF; Premkumar, DR, 2013) |
"Glioblastoma is an aggressive primary brain tumor with a 5-year survival rate of less than 5%." | ( Greenwood, JA; La Du, J; Lal, S; Tanguay, RL, 2012) |
"Glioblastoma is a deadly cancer with intrinsic chemoresistance." | ( Anelli, V; Bassi, R; Brioschi, L; Campanella, R; Caroli, M; De Zen, F; Gaini, SM; Giussani, P; Riboni, L; Riccitelli, E; Viani, P, 2012) |
"Glioblastoma is universally fatal because of its propensity for rapid recurrence due to highly migratory tumor cells." | ( Adamson, DC; Bigner, D; Bortoff, K; Di, C; Duncan, C; Fu, J; Gregory, S; Killela, P; Lin, N; McLendon, R; Truszkowski, P, 2012) |
"Glioblastomas are known to be highly chemoresistant, but HDAC inhibitors (HDACi) have been shown to be of therapeutic relevance for this aggressive tumor type." | ( Bajbouj, K; Hartig, R; Mawrin, C; Roessner, A; Schneider-Stock, R; Schulze-Luehrmann, J; Wilisch-Neumann, A, 2012) |
"Glioblastoma is the most common and most malignant primary brain tumor in adults." | ( Hedderich, J; Mehdorn, HM; Nabavi, A; Stark, AM; van de Bergh, J, 2012) |
"Glioblastoma is a devastating, incurable disease with few known prognostic factors." | ( Berger, MS; Brem, S; Browning, JE; Buckner, JC; Chang, SM; Decker, PA; Egan, KM; Fridley, BL; Hansen, HM; Jenkins, RB; Kosel, ML; Lachance, DH; Madden, MH; McCoy, LS; Nabors, LB; O'Neill, BP; Olson, JJ; Patoka, JS; Prados, MD; Rice, T; Smirnov, I; Thompson, RC; Tihan, T; Wiemels, JL; Wiencke, JK; Wrensch, MR; Xiao, Y, 2012) |
"Glioblastoma is the most aggressive brain tumour of the adult with a high rate of mortality." | ( Baruzzi, A; Cerasoli, S; de Biase, D; Marucci, G; Morandi, L; Pession, A; Taccioli, C; Visani, M, 2012) |
"Pediatric glioblastoma is a malignant disease with an extremely poor clinical outcome." | ( Chen, SH; Cheng, CC; Chiu, TH; Huang, YT; Lai, PC; Yang, SH, 2012) |
"The fatal nature of glioblastoma is caused by tumor-initiating glioblastoma cells." | ( Altaner, C; Altanerova, V, 2012) |
"Most patients with glioblastoma are older than 60 years, but treatment guidelines are based on trials in patients aged only up to 70 years." | ( Abacioglu, U; Frappaz, D; Grønberg, BH; Hegi, ME; Henriksson, R; Lhermitte, B; Malmström, A; Marosi, C; Rosell, J; Schultz, H; Stupp, R; Tavelin, B, 2012) |
"Glioblastoma is one of the most lethal and common malignant human brain tumors, with aggressive proliferation and highly invasive properties." | ( Chang, KC; Jeong, JJ; Kim, HJ; Lee, JH, 2012) |
"Glioblastoma is one of the most aggressive tumors with poor prognosis." | ( Akiyama, T; Ao-Kondo, H; Koyama-Nasu, R; Kozuka-Hata, H; Nasu-Nishimura, Y; Oyama, M; Tsumoto, K, 2012) |
"Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome." | ( Balabanov, S; Bokemeyer, C; Braig, M; Hagel, C; Hauber, J; Lamszus, K; Pällmann, N; Preukschas, M; Schulte, A; Sievert, H; Weber, K, 2012) |
"Glioblastoma is a brain tumor with poor prognosis in the therapy of which operation, postoperative temozolomide sensitized radiochemotherapy followed by temozolomide monotherapy offer the best chances." | ( Bassam, A; Nagy, KA; Pikó, B; Puskásné Szatmári, K; Török, E; Vághy, R; Vargáné Tamás, R, 2012) |
"Glioblastoma is the most common and most aggressive form of malignant glioma and is very difficult to treat." | ( Nakabayashi, H; Shimizu, K, 2012) |
"Glioblastoma is the most common and most lethal form of brain tumor in human." | ( Chen, F; Kang, D; Li, X; Song, Y; Wang, J; Yang, CJ; Zhang, W; Zhu, M; Zhu, Z; Zou, Y, 2012) |
"Glioblastoma is the most frequent primary malignant brain tumor in adults." | ( Caporello, P; Enrici, RM; Minniti, G; Scaringi, C, 2012) |
"Glioblastoma is a rapidly evolving high-grade astrocytoma that is distinguished pathologically from lower grade gliomas by the presence of necrosis and microvascular hyperplasia." | ( Calvo, GF; Martínez-González, A; Pérez Romasanta, LA; Pérez-García, VM, 2012) |
"Glioblastomas are very difficult tumors to treat because they are highly invasive and disseminate within the normal brain, resulting in newly growing tumors." | ( Akino, T; Bielenberg, DR; Coma, S; Italiano, JE; Klagsbrun, M; König, C; Mammoto, A; Nakayama, H; Sandlund, J; Shimizu, A; Wang, P, 2013) |
"Glioblastoma is the most common form of primary adult brain tumors." | ( Adrados, I; Allison, J; Arauz, R; Desprez, PY; Fukuyo, Y; Kawamura, R; Khan, S; Limbad, C; McAllister, SD; Moore, DH; Murase, R; Nguyen, D; Pakdel, A; Singer, E; Soroceanu, L; Yount, GL, 2013) |
"Glioblastomas are grade IV brain tumors characterized by high aggressiveness and invasiveness, giving patients a poor prognosis." | ( Barbieri, F; Carra, E; Daga, A; Favoni, RE; Florio, T; Marubbi, D; Pattarozzi, A, 2013) |
"We here show that glioblastomas are capable to downregulate MGMT expression independently of promoter methylation by elongation of the 3'-UTR of the mRNA, rendering the alternatively polyadenylated transcript susceptible to miRNA-mediated suppression." | ( Egensperger, R; Hinske, LC; Hoefig, K; Kreth, FW; Kreth, S; Limbeck, E; Schütz, SV; Thon, N, 2013) |
"Glioblastoma is refractory to conventional therapies." | ( Cheng, Z; Gong, Y; Knapp, S; Lu, K; Lu, X; Ma, Y; Muller, S; Pierce, LA; Thompson, RC; Wang, J, 2013) |
"Glioblastoma is one of the intractable cancers and is highly resistant to ionizing radiation." | ( Asanuma, T; Inanami, O; Kino, J; Kubota, N; Kuwabara, M; Meike, S; Nagane, M; Yamamori, T; Yasui, H, 2013) |
"Recurrent glioblastoma is nearly always fatal, with median survival rates of approximately 12-14 months." | ( Banfi, R; Cecchi, M; Ceroti, M; Vaiani, M, 2013) |
"Glioblastoma is a notoriously difficult tumor to treat because of its relative sanctuary in the brain and infiltrative behavior." | ( Alkins, RD; Brodersen, PM; Hynynen, K; Sodhi, RN, 2013) |
"Glioblastoma is the most common malignant primary brain tumour in adults and one of the most lethal of all cancers." | ( Carrasco, MP; Marco, C; Martín-Fernández, M; Ríos, A; Ríos-Marco, P; Soria-Bretones, I, 2013) |
"Glioblastoma are one of the mostly vascularized tumors and are histologically characterized by abundant endothelial cell proliferation." | ( Batchelor, TT; de Groot, J; Reardon, DA, 2013) |
"Glioblastoma is the most common and lethal cancer of the central nervous system." | ( Bai, Y; Bao, ZS; Chen, Y; Wang, LJ; Yan, ZH; Zhang, QG; Zhang, W, 2013) |
"Glioblastoma is the most common type of primary brain tumors." | ( Chen, F; Fang, J; Guo, Y; Qu, Q; Yan, K; Zhou, M, 2013) |
"Glioblastomas are the most frequent and aggressive intracranial neoplasms in humans, and despite advances and the introduction of the alkylating agent temozolomide in therapy have improved patient survival, resistance mechanisms limit benefits." | ( Caroli, M; Condomitti, G; Di Vito, C; Galli, R; Giussani, P; Riboni, L; Riccitelli, E; Tringali, C; Viani, P, 2013) |
"Glioblastoma is the most frequent brain tumor of glial origin in adults." | ( Bachem, MG; Debatin, KM; Dwucet, A; Halatsch, ME; Karpel-Massler, G; Kast, RE; Nonnenmacher, L; Westhoff, MA; Wirtz, CR; Zhou, S, 2013) |
"Glioblastoma is the most lethal brain cancer." | ( Li, C; Li, X; Liu, X; Yan, B; Zhang, Q; Zhou, H, 2013) |
"Glioblastoma is a highly malignant, invariably fatal brain tumor for which effective pharmacotherapy remains an unmet medical need." | ( Brüstle, O; Fimmers, R; Glas, M; Gogolok, S; Höfer, H; Keller, M; Klaas, L; Koch, P; Leinhaas, A; Normann, S; Pietsch, T; Pincus, DW; Reinartz, R; Scheffler, B; Schelle, R; Simon, M; Steindler, DA; Trageser, D; Waha, A; Wieland, A; Yachnis, AT, 2013) |
"Glioblastoma is a highly vascularized brain tumor, and antiangiogenic therapy improves its progression-free survival." | ( Jiang, A; Jiang, E; Kieran, MW; Mammoto, A; Mammoto, T; Panigrahy, D, 2013) |
"Glioblastomas are the most aggressive forms of primary brain tumors due to their tendency to invade surrounding healthy brain tissues, rendering them largely incurable." | ( Ding, T; Fu, L; Gu, F; Jiang, W; Li, W; Li, Z; Liu, X; Ma, Y; Sun, K; Tian, C; Ying, G; Zhou, Y, 2013) |
"Glioblastoma is the most aggressive and common type of malignant brain tumor in humans, with a median survival of 15 months." | ( Kaur, B; Meisen, WH; Racoma, IO; Wang, QE; Wani, AA, 2013) |
"Glioblastoma is the most aggressive cerebral gliomas." | ( Feng, J; Leng, X; Li, J; Li, W; Lian, S; Wang, C; Wang, H; Zhang, X, 2014) |
"Glioblastoma is a highly aggressive malignant disease with notable resistance to chemotherapy." | ( Han, G; Hu, X; Li, Y; Liu, J; Wang, L; Yue, Z; Zhao, R; Zhao, W; Zhou, X, 2013) |
"Glioblastoma is the most prevalent and malignant primary brain tumor in adults, and its response to current therapies is limited." | ( Ji, H; Lu, Z, 2013) |
"Glioblastomas are the most aggressive primary brain tumors and their heterogeneity and complexity often renders them non responsive to various conventional treatments." | ( Kaur, G; Mishra, R, 2013) |
"Glioblastoma is one of the most lethal and prevalent malignant human brain tumors, with aggressive proliferation and highly invasive properties." | ( Chang, KC; Eun, SY; Joo, YN; Kim, HJ; Lee, JH; Park, SW, 2014) |
"Radiosurgery for glioblastoma is limited to the development of resistance, allowing tumor cells to survive and initiate tumor recurrence." | ( Chen, Z; Hu, Z; Tu, J, 2013) |
"Human glioblastoma is highly resistant to chemotherapy with temozolomide." | ( Chung, H; Jo, S; Kim, IC; Kim, S; Kim, TU; Lee, H; Yim, JH, 2013) |
"Epithelioid glioblastoma is among the rarest variants of glioblastoma and is not formally recognized in the World Health Organization classification; it is composed of monotonous, discohesive sheets of small, round cells with eccentric nuclei and eosinophilic cytoplasm devoid of cytoplasmic stellate processes, showing the retention of nuclear staining of INI-1 protein." | ( Hirato, J; Ikota, H; Kurihara, H; Nagaishi, M; Nakazato, Y; Nobusawa, S; Ogawa, A; Okura, N; Yokoo, H, 2014) |
"Glioblastomas are lethal tumors characterized by malignant proliferation and recurrence promoted partly by glioblastoma stem cells (GSCs)." | ( Bai, YF; Chen, J; Guo, HB; Liao, HZ; Liu, TZ; Qiu, SC; Wang, X; Yan, XH; Yang, YQ; Zhang, SZ, 2014) |
"Human glioblastoma is the most frequent and aggressive type of brain tumors." | ( Baklaushev, VP; Chekhonin, VP; Grinenko, NP; Gubskiy, IL; Gurina, OI; Kabanov, AV; Kardashova, KSh; Khalansky, AS; Melnikov, PA; Nukolova, NN; Yusubalieva, GM, 2015) |
"Glioblastoma is known as one of the most aggressive human cancers." | ( Akbarzadeh, A; Alavi, SE; Ebrahimi Shahmabadi, H; Eslamifar, A; Koohi Moftakhari Esfahani, M; Mohammadi Anaraki, G; Movahedi, F, 2014) |
"Glioblastoma is the most common brain tumor in adults." | ( Depping, R; Jelkmann, W; Sun, W, 2014) |
"Glioblastoma is the most common malignant primary brain tumor." | ( Boots-Sprenger, SH; Hiddingh, L; Hulleman, E; Jeuken, J; Kaspers, GJ; Noske, DP; Tannous, BA; Teng, J; Tops, B; Vandertop, WP; Wesseling, P; Wurdinger, T, 2014) |
"Glioblastoma is the most common malignant brain tumor in adults and characterized by a poor prognosis." | ( Deenen, R; Florea, AM; Frei, K; Happold, C; Lamszus, K; Reifenberger, G; Roth, P; Silginer, M; Weller, M, 2014) |
"Glioblastoma is an invasive tumor of the central nervous system." | ( Babaei, E; Bilia, AR; Isacchi, B; Marra, F; Mowla, SJ; Najafi, F; Sadeghizadeh, M; Tahmasebi Mirgani, M, 2014) |
"Glioblastoma is the most common and most aggressive malignant primary brain tumor in humans, accounting for 52 % of all functional tissue brain tumor cases and 20 % of all intracranial tumors." | ( Cheng, T; Gao, Y; Guo, W; Li, S; Liu, Y; Ma, W; Zhou, G, 2014) |
"Glioblastoma are the most frequent and malignant human brain tumors, having a very poor prognosis." | ( Alt, A; Debatin, KM; Fichtner, I; Friesen, C; Hilger, R; Hormann, I; Miltner, E; Roscher, M, 2014) |
"Glioblastoma is an aggressive tumor that occurs in both adult and pediatric patients and is known for its invasive quality and high rate of recurrence." | ( Keating, AK; Knubel, KH; Nelson, S; Pernu, BM; Pierce, AM; Sufit, A, 2014) |
"Glioblastoma is the most malignant and lethal form of astrocytoma, with patients having a median survival time of approximately 15 months with current therapeutic modalities." | ( Al-Abed, Y; Didier, S; Issaivanan, M; Miller, IS; Murray, DW; Ruggieri, R; Symons, M; Turner, TH, 2014) |
"Glioblastoma is one of the most aggressive brain tumors with high morbidity and mortality." | ( Han, XJ; Jiang, LP; Lai, QN; Wan, YY; Wang, JB; Wei, YF; Xin, HB; Yang, ZJ; Zhang, JF, 2014) |
"Glioblastomas are highly malignant brain tumours." | ( Becker, S; Buzug, TM; Mang, A; Schuetz, TA; Toma, A, 2014) |
"Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients." | ( Chen, Y; Cheng, L; Huang, C; Lan, J; Lei, Y; Li, J; Li, Y; Liu, R; Nice, EC; Wang, K; Wei, Y; Xiang, R; Xie, N; Yuan, K; Zhang, T; Zou, L, 2014) |
"Glioblastoma is the most prevalent primary brain tumor and is essentially universally fatal within 2 years of diagnosis." | ( Bai, Y; Flavahan, W; Lathia, JD; Mattson, MP; Rich, JN; Zhang, P, 2014) |
"Almost all glioblastomas are intrinsically resistant to chemotherapeutic temozolomide (TMZ) or develop resistance during treatment." | ( Hiddingh, L; Hulleman, E; Jeuken, J; Kaspers, GJ; Noske, DP; Raktoe, RS; Vandertop, WP; Wesseling, P; Wurdinger, T, 2014) |
"Glioblastoma is the most common and aggressive primary brain tumor in adults, with a poor prognosis because of its resistance to radiotherapy and chemotherapy." | ( Camacho, L; Guerrero, PA; Marchetti, D; Yin, W, 2015) |
"Glioblastoma is a highly lethal cancer." | ( Nakano, I, 2014) |
"Grade IV glioma (glioblastoma) is one of the most common brain/central nervous system cancers." | ( Hay, JW; Messali, A; Villacorta, R, 2014) |
"Glioblastoma is the most aggressive primary brain tumor in adults." | ( Chinot, O; Delattre, JY; Hoang-Xuan, K; Idbaih, A; Loundou, A; Sanson, M; Tabouret, E, 2014) |
"Grade IV glioblastoma is characterized by increased kinase activity of epidermal growth factor receptor (EGFR); however, EGFR kinase inhibitors have failed to improve survival in individuals with this cancer because resistance to these drugs often develops." | ( Aldape, K; Berens, ME; Carrera-Silva, EA; Dietrich, JD; Errasti, AE; Ghosh, S; Gibbs, D; Hulme, C; Kusne, Y; Loftus, JC; Lu, Z; Mandell, EK; Perry, AS; Rothlin, CV; Rushing, EJ; Sanai, N; Yang, W, 2014) |
"Glioblastoma is a highly aggressive, common brain tumor with poor prognosis." | ( Corbacioglu, S; Debatin, KM; Engelke, J; Fulda, S; Halatsch, ME; Karpel-Massler, G; Nonnenmacher, L; Simmet, T; Westhoff, MA, 2015) |
"Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the prognosis is poor, with a median survival of 16 to 19 months and poor quality of life throughout the disease course." | ( Brennan, CW; DeAngelis, LM; Omuro, AM; Thomas, AA, 2014) |
"Glioblastoma is an aggressive tumor with heterogeneous molecular features and complex host interactions, many of which are amenable to therapeutic intervention." | ( Brennan, CW; DeAngelis, LM; Omuro, AM; Thomas, AA, 2014) |
"Glioblastoma is the most common and most fatal primary malignant brain tumor in adults." | ( Folkerth, RD; Milner, DA; Ramkissoon, SH; Solomon, IH, 2014) |
"Glioblastoma is an aggressive malignancy, which is notorious for its poor prognosis." | ( Fei, Z; He, X; Liu, W; Wang, Y, 2015) |
"Glioblastoma is the most common malignant brain tumor in adults and carries a particularly poor prognosis." | ( Barnholtz-Sloan, JS; Bauchet, L; Woehrer, A, 2014) |
"Glioblastoma is an aggressive malignancy, which is associated with poor prognosis." | ( Guo, H; Guo, M; Wang, Y; Yang, L, 2015) |
"Glioblastoma is the most frequent primary brain tumor in adults." | ( Baeza-Kallee, N; Beclin, C; Carré, M; Colin, C; Denicolaï, E; Figarella-Branger, D; Jiglaire, CJ; Mercurio, S; Tchoghandjian, A, 2014) |
"Glioblastomas are highly aggressive adult brain tumors with poor clinical outcome." | ( Artuso, S; Balestrieri, ML; Caraglia, M; De Rosa, G; Leonetti, C; Luce, A; Lusa, S; Porru, M; Salzano, G; Stoppacciaro, A; Zappavigna, S, 2014) |
"Glioblastoma is the most fatal type of brain tumor, requiring a better chemotherapy regime to prolong the survival of the patient." | ( Mohanta, GP; Mohanty, AK, 2015) |
"Glioblastoma is the most common adult malignant primary brain tumor." | ( Ahluwalia, MS; Peereboom, DM; Venur, VA, 2015) |
"Glioblastoma is the most aggressive primary brain tumor, and is associated with a very poor prognosis." | ( Alder, JE; Boissinot, M; Droop, A; Hayes, J; Hughes, TA; Lawler, SE; Shaw, L; Short, SC; Thygesen, H; Tumilson, C; Westhead, D, 2015) |
"Glioblastoma is a rapidly infiltrating tumor that consistently rematerializes despite various forms of aggressive treatment." | ( Cohen-Gadol, AA; Harvey, KA; Pollok, K; Saaddatzadeh, MR; Siddiqui, RA; Wang, H; Xu, Z, 2015) |
"Glioblastoma is a devastating primary brain tumor resistant to conventional therapies." | ( Battastini, AM; Bishop, AJR; Braganhol, E; Bristot, IJ; Figueiró, F; Forcelini, CM; Gelain, DP; Klafke, K; Moreira, JCF; Morrone, M; Paludo, FJ; Terra, SR; Zanotto-Filho, A, 2015) |
"Glioblastoma is the most common brain tumor and is characterized with robust invasion and migration potential resulting in poor prognosis." | ( Li, JC; Rao, W; Shi, ZX; Si, JW; Wang, H; Wang, ND; Wang, ZR; Zhao, J, 2015) |
"Glioblastoma is the most common and most aggressive primary brain malignancy." | ( Chang, MY; Chou, YC; Chung, JG; Harnod, T; Hung, CH; Lee, HT; Shen, CC; Wang, MJ, 2015) |
"Glioblastoma is the most frequent primary malignant brain tumor in adults." | ( Benoit, JP; Danhier, F; Lagarce, F; Lemaire, L; Messaoudi, K, 2015) |
"Glioblastoma is the most malignant brain tumor, exhibiting remarkable resistance to treatment." | ( Correia, S; Costa, BM; Costa, S; Gonçalves, CS; Gonçalves, T; Lopes, JM; Oliveira, AI; Pinto, AA; Pinto, L; Pojo, M; Reis, RM; Rocha, M; Rodrigues, AJ; Sousa, N; Xavier-Magalhães, A, 2015) |
"Glioblastoma is the most common, aggressive and highly malignant type of primary brain tumor." | ( Liao, A; Lin, KW; Qutub, AA, 2015) |
"Multifocal glioblastoma is an uncommon and refractory subtype of high-grade glioma since the burden of masses could not be eliminated simply by operation, and it is getting even harder to control if some deep structures, like thalamus and pineal region, are involved." | ( Gao, Z; Hao, S; Liu, Y; Yu, L, 2015) |
"Glioblastomas are progressive brain tumors with devastating proliferative and invasive characteristics." | ( Barszczyk, A; Chen, WL; Deurloo, M; Feng, ZP; Liu, B; Rutka, JT; Sun, HS; Turlova, E; Yang, BB, 2015) |
"Glioblastoma is the most frequent primary malignant brain tumor in adults." | ( Danhier, F; des Rieux, A; Fourniols, T; Leprince, JG; Préat, V; Randolph, LD; Staub, A; Vanvarenberg, K, 2015) |
"Glioblastomas are differentially sensitive to Delta24-RGD." | ( Berghauser Pont, LM; de Vrij, J; Dirven, CM; Kaufmann, JK; Kleijn, A; Kloezeman, JJ; Lamfers, ML; Leenstra, S; van den Bossche, W, 2015) |
"Glioblastomas are invasive therapy resistant brain tumors with extremely poor prognosis." | ( Behnan, J; Fjerdingstad, HB; Glover, JC; Grieg, Z; Joel, M; Langmoen, IA; Mikkelsen, B; Mughal, AA; Murrell, W; Palmero, S; Sandberg, CJ; Stangeland, B, 2015) |
"Glioblastoma are among the most angiogenic tumors." | ( Burghardt, I; Frei, K; Krishnan, S; Szabo, E; Tabatabai, G; Weller, M, 2015) |
"Glioblastoma is the deadliest brain tumor in humans." | ( Chakrabarti, M; Ray, SK, 2015) |
"Glioblastoma is the most common intracranial malignancy that constitutes about 50 % of all gliomas." | ( Eder, K; Kalman, B, 2015) |
"Glioblastoma is the most aggressive primary brain tumor with hypoxia-associated morphologic features including pseudopalisading necrosis and endothelial hyperplasia." | ( Chi, SG; Chung, YG; Kang, SH; Park, DH; Park, KJ; Yu, MO, 2015) |
"Glioblastoma is the most aggressive primary brain malignancy, and the efficacy of multimodality treatments remains unsatisfactory." | ( Chang, MY; Chou, YC; Chung, JG; Harnod, T; Hung, CH; Lee, HT; Liu, HC; Wang, MJ; Yu, FS, 2015) |
"Epileptogenic glioblastomas are thought to convey a favorable prognosis, either due to early diagnosis or potential antitumor effects of antiepileptic drugs." | ( Berendsen, S; Bours, V; Broekman, ML; Kauw, F; Kroonen, J; Poulet, C; Robe, PA; Seute, T; Snijders, TJ; Spliet, WG; Varkila, M; Willems, M, 2016) |
"Glioblastomas are the most common brain tumors in humans." | ( Carpinelli, G; Castigli, E; Conte, C; Degrassi, F; Di Bari, M; Fiore, M; Iorio, E; Ricordy, R; Sciaccaluga, M; Tata, AM; Tombolillo, V, 2015) |
"Glioblastoma is the most lethal brain tumor." | ( Chakrabarti, M; Ray, SK, 2015) |
"Glioblastoma is the most frequent primary brain tumor in adults." | ( Bâ, M; Bruce, JN; Canoll, P; Halatsch, ME; Karpel-Massler, G; Shu, C; Siegelin, MD; Westhoff, MA, 2015) |
"Glioblastoma is the most common and aggressive form of intrinsic brain tumor." | ( Bunse, L; Burghardt, I; Gramatzki, D; Hao, N; Leske, H; Platten, M; Roth, P; Rushing, EJ; Silginer, M; Weller, M, 2016) |
"Glioblastoma is the most common tumor of the central nervous system and one of the hardest tumors to treat." | ( Borges, KS; Brassesco, MS; de Oliveira, JC; dos Santos, MH; Ionta, M; Pezuk, JA; Sales, L; Scrideli, CA; Tone, LG, 2015) |
"Glioblastoma is the most malignant primary brain tumor and is highly infiltrative." | ( Ang, BT; Chong, YK; Holbrook, JD; Koh, GR; Koh, LW; Kon, OL; Lim, GG; Lim, KL; Nadarajah, M; Ng, I; Ng, WH; Sandanaraj, E; Tan, MS; Tan, NS; Tang, C; Thangaveloo, M; Toh, TB, 2016) |
"Glioblastoma is the most common and lethal type of primary brain tumor." | ( Gao, X; Li, X; Li, Z; Liang, G; Luo, L; Song, Z; Su, J; Wang, X; Xie, P; Zhu, T, 2015) |
"Glioblastoma is the deadliest brain tumor in humans." | ( Chakrabarti, M; Ray, SK, 2016) |
"Glioblastomas are highly aggressive tumors that contain treatment resistant stem-like cells." | ( Chu, Q; Eberhart, CG; Kahlert, UD; Kaur, H; Liu, Y; Maitani, K; Miyahara, H; Natsumeda, M; Zhang, H, 2016) |
"Glioblastoma is the most common and the most lethal primary brain tumor in adults." | ( , 2016) |
"Glioblastoma is the most common malignant brain tumor accounting for more than 54 % of all gliomas." | ( Aithal, MG; Chand, AK; Narayanappa, R; Rout, P, 2016) |
"Glioblastoma is the most devastating primary malignancy of the central nervous system in adults." | ( Barnett, GH; Caroli, M; Chen, TC; Desai, R; Engelhard, HH; Fink, KL; Hegi, ME; Henson, JW; Honnorat, J; Hottinger, AF; Idbaih, A; Kanner, AA; Kesari, S; Kew, Y; Kirson, ED; Landolfi, J; Lieberman, F; Palti, Y; Ram, Z; Silvani, A; Sroubek, J; Steinberg, DM; Stupp, R; Taillibert, S; Taylor, LP; Toms, SA; Tran, DD; Tran, ND; Weinberg, U; Zhu, JJ, 2015) |
"Glioblastoma is the most common and aggressive primary brain malignancy." | ( Chang, MY; Chang, SJ; Chou, YC; Chung, JG; Harnod, T; Hung, CH; Lee, HT; Liu, HC; Shen, CC; Wang, MJ, 2017) |
"Glioblastoma is a malignant human cancer that confers a dismal prognosis." | ( Liang, Z; Long, L; Wang, L; Wang, W, 2015) |
"Glioblastoma is almost always incurable and most older patients survive less than 6 months." | ( Mohile, NA, 2016) |
"GBM (Glioblastoma) is the most malignant human brain tumor with median survival of one year." | ( Lal, N; Luthra, PM, 2016) |
"Glioblastoma is one of the most malignant primary tumors, and the prognosis for glioblastoma patients remains poor." | ( Ahn, KS; Choi, M; Ha, IJ; Kim, SH; Lee, JH; Lee, SG; Lim, SL; Park, D; Park, SY; Yun, M, 2016) |
"Glioblastoma is an aggressive, invasive tumor of the central nervous system (CNS)." | ( Behera, P; Chiocca, EA; Cho, CF; Lawler, SE; Nowicki, MO; Speranza, MC, 2016) |
"Glioblastoma is the most common and deadly primary brain tumor in adults." | ( Feng, F; Ling, Z; Sun, C; Wang, L; Wang, S; Wu, B; Xia, L; Yu, Y, 2016) |
"Glioblastoma is a unique model of non-metastasising disease that kills the vast majority of patients through local growth, despite surgery and local irradiation." | ( Giatromanolaki, A; Koukourakis, MI; Mitrakas, AG, 2016) |
"Glioblastomas are extremely aggressive brain tumors with highly invasive properties." | ( Ang, BT; Chong, YK; Gauthier, NC; Guetta-Terrier, C; Krishnasamy, A; Ladoux, B; Monzo, P; Ng, WH; Sathe, SR; Sheetz, MP; Tang, C; Yim, EK, 2016) |
"Glioblastoma is an uncommon and aggressive primary brain tumor with incidence of 3 per 100,000 annually." | ( Golzy, N; Pouratian, N; Sharim, J; Tashjian, R, 2016) |
"Glioblastoma is one of the most lethal cancers in humans, and with existing therapy, survival remains at 14." | ( Aman, A; Cairncross, JG; Dang, NH; Datti, A; Easaw, JC; Grinshtein, N; Hao, X; Kaplan, DR; King, JC; Luchman, A; Lun, X; Robbins, SM; Senger, DL; Uehling, D; Wang, X; Weiss, S; Wells, JC; Wrana, JL, 2016) |
"Glioblastoma is an invasive primary brain malignancy that typically infiltrates the surrounding tissue with malignant cells." | ( Canoll, P; Chow, DS; Filippi, CG; Grinband, J; Hillman, EM; Horenstein, CI; Lignelli, A, 2016) |
"Glioblastoma is the most common and most aggressive primary brain tumour." | ( Alikhanyan, K; Barker, CA; Beal, K; Bishop, AJ; Chan, TA; Chang, M; Dai, C; Donnola, S; Gorlia, T; Hambardzumyan, D; Hentschel, B; Holland, EC; Hosni-Ahmed, A; Jones, TS; Ozawa, T; Pattwell, SS; Pitter, KL; Schlegel, U; Stupp, R; Tamagno, I; Weller, M, 2016) |
"Recurrent glioblastoma is associated with a poor overall survival." | ( Aerts, JL; Benteyn, D; De Keersmaecker, B; Du Four, S; Duerinck, J; Maenhout, SK; Neyns, B; Thielemans, K, 2016) |
"Glioblastoma is the most frequent malignant brain tumor." | ( Alonso, MM; Fueyo, J; García-Garzón, A; Gomez-Manzano, C; Gonzalez-Huarriz, M; Jiang, H; Lang, FF; Martinez de Irujo, JJ; Xipell, E, 2016) |
"Glioblastoma is the most frequent and malignant brain tumor." | ( Battastini, AM; Coelho, BP; de Quadros, AH; Gaelzer, MM; Gonçalves, CA; Guerra, MC; Guma, FC; Hoppe, JB; Salbego, CG; Setton-Avruj, P; Terra, SR; Usach, V, 2016) |
"Glioblastoma is characterized by an aggressive and aberrant vascular network that promotes tumor progression and hinders effective treatment; the median survival is 16 mo despite standard-of-care therapies." | ( Behling, K; Gutin, PH; López Puebla, JC; Maguire, WF; McDevitt, MR; O'Donoghue, J; Ruggiero, A; Scheinberg, DA; Sprinkle, SR, 2016) |
"Glioblastoma is an aggressive brain cancer requiring improved treatments." | ( Greenwood, JA; Punnoose, A; Tanguay, RL; Wehmas, LC, 2016) |
"Glioblastoma is associated with poor prognosis with a median survival of one year." | ( Andersson, U; Antti, H; Björkblom, B; Johannesen, TB; Jonsson, P; Langseth, H; Melin, B; Mörén, L; Wibom, C, 2016) |
"Glioblastoma is a malignant brain tumor originating in the central nervous system." | ( Chen, Z; Gao, Z; Lai, X; Mao, G; Qu, J; Zhang, L; Zhu, J; Zhu, X, 2016) |
"Glioblastoma is one of the most aggressive solid tumors, and, despite treatment options such as surgery, radiation, and chemotherapy, its prognosis remains grim." | ( Chiocca, EA; Lim, M; Weller, M, 2016) |
"Glioblastoma is the most common malignant brain tumor in adults." | ( Anota, A; Bonnetain, F; Campello, C; Castera, D; Chauffert, B; Chinot, O; Dabakuyo, S; Dalban, C; Ducray, F; Durando, X; Fabbro, M; Feuvret, L; Frappaz, D; Frenay, M; Ghiringhelli, F; Guillamo, JS; Paquette, B; Schott, R; Skrzypski, J; Taillandier, L; Taillia, H; Tennevet, I; Vernerey, D, 2016) |
"Glioblastoma is a fatal and incurable cancer with the hyper-activated mTOR pathway." | ( Deng, H; Li, J; Liu, X; Luo, M; Tang, H; Wang, G, 2016) |
"Glioblastoma is the most common and malignant brain tumor in humans." | ( Chakrabarti, M; Klionsky, DJ; Ray, SK, 2016) |
"Glioblastoma is the most malignant form of brain tumor." | ( Choi, E; Han, J; Lee, D; Lee, M; Oh, J; Rhim, T; Tan, X, 2017) |
"Glioblastomas are highly invasive and aggressive primary brain tumors." | ( Davidoff, AM; Pfeffer, LM; Wang, R, 2016) |
"Glioblastoma is the most malignant tumor of the central nervous system and still lacks effective treatment." | ( Berghauser Pont, LM; Besselink, NJ; Caljouw, E; Dekker, LJ; Dubbink, HJ; Hoogstraat, M; Joore, J; Kloezeman, J; Lamfers, ML; Leenstra, S; Luider, TM; Martens, JW; Pierson, T; Sleijfer, S; Spoor, JK; van der Kaaij, M; Venkatesan, S; Zeneyedpour, L, 2016) |
"Glioblastoma is the most malignant primary brain tumor, with a median survival of less than 2 years." | ( Clark, PA; Eliceiri, KW; Kuo, JS; Pointer, KB; Robertson, GA; Salamat, MS, 2017) |
"Glioblastoma is a malignant tumor of astrocytic origin that is highly invasive, proliferative and angiogenic." | ( Amaral, R; da Fonseca, AC; Garcia, C; Geraldo, LH; Lima, FR; Matias, D, 2016) |
"Pediatric glioblastoma is one of the most common and most deadly brain tumors in childhood." | ( , 2016) |
"Glioblastomas are the most aggressive of all gliomas and have the worst prognosis, with 5-year survival rates of less than 10%." | ( Hirose, Y; Ohba, S, 2016) |
"Glioblastoma is one of the most vascular brain tumour and highly resistant to current therapy." | ( Fang, S; Liu, B; Liu, Y; Sun, Q, 2016) |
"Glioblastoma is an aggressive brain tumor that requires multidisciplinary treatment including adjuvant radiotherapy, chemotherapy, and adjunct corticosteroids." | ( Hatakeyama, S; Ikeda, T; Morisawa, Y; Norizuki, M; Okabe, T; Onishi, T; Sasahara, T; Suzuki, J; Toshima, M; Yokota, H, 2017) |
"Glioblastoma is an aggressive and incurable primary brain tumor." | ( Mirzaei, R; Sarkar, S; Yong, VW, 2017) |
"Glioblastoma is a high-grade cerebral tumor with local recurrence and poor outcome." | ( Duhamel, A; Leroux, B; Leroy, HA; Maurage, CA; Mordon, S; Reyns, N; Vermandel, M; Vignion-Dewalle, AS, 2017) |
"Glioblastoma is an aggressive tumor that is associated with distinctive infiltrating microglia/macrophages populations." | ( Chen, J; Chen, X; Ji, M; Jia, J; Jiang, J; Jin, J; Lai, F; Li, W; Xue, N; Yang, H; Zhang, J; Zhang, M; Zhou, Q, 2017) |
"Glioblastoma is the most common malignant brain tumor." | ( Assad Kahn, S; Aulestia, FJ; Cheshier, SH; Chneiweiss, H; Daubeuf, F; Dong, J; Dubois, LG; El-Habr, EA; Frossard, N; Haiech, J; Junier, MP; Kilhoffer, MC; Leclerc, C; Moreau, M; Néant, I; Tounsi, N; Zeniou, M, 2017) |
"Glioblastoma is a common malignant brain tumor and it is refractory to therapy because it usually contains a mixture of cell types." | ( Chan, TM; Deng, Y; Hu, X; Liu, PC; Lu, G; Poon, WS; Su, XW; Wang, CD; Zhou, JY, 2017) |
"Glioblastoma is the most aggressive manifestation of malignant gliomas and considered to be among the deadliest forms of human cancers." | ( Chen, L; Fan, J; Li, Y; Liu, Z; Wang, J; Xu, R, 2017) |
"Glioblastoma is a kind of malignant gliomas that is almost impossible to cure due to the poor drug transportation across the blood-brain barrier and the existence of glioma stem cells." | ( Li, X; Tang, H; Wang, Y; Xu, H; Yan, H; Ying, X, 2017) |
"Glioblastoma is the most frequent and most malignant brain tumor with the patients having a median survival of only 14." | ( Aaberg-Jessen, C; Halle, B; Jensen, SS; Kristensen, BW; Petterson, SA, 2017) |
"Glioblastoma is the most common and deadliest primary brain tumor for humans." | ( Belluco, S; Berger, F; Bonnefont-Rebeix, C; Carozzo, C; Chuzel, T; Dreyfus, M; Khoshnevis, M; Leveneur, O; Pillet-Michelland, E; Ponce, F; Roger, T, 2017) |
"Glioblastoma is associated with a poor prognosis in the elderly." | ( Back, M; Baumert, BG; Brandes, AA; Cairncross, JG; Chinot, O; Ding, K; Fariselli, L; Fay, M; Feuvret, L; Franceschi, E; Golfinopoulos, V; Hirte, H; Laigle-Donadey, F; Laperriere, N; Mason, WP; Menten, J; Nishikawa, R; O'Callaghan, CJ; Osoba, D; Perry, JR; Phillips, C; Roa, W; Rossiter, JP; Sahgal, A; Tills, M; Wick, A; Wick, W; Winch, C, 2017) |
"Optic nerve glioblastoma is a rare entity that usually presents with rapidly progressive vision loss, which eventually results in blindness and, ultimately, death." | ( Beatriz Lopes, M; Caruso, JP; Chen, CJ; Ding, D; Hays, MA; Mastorakos, P; Shaffrey, ME; Taylor, DG, 2018) |
"Glioblastoma is the most common and most malignant primary brain tumor with a median survival of 15 months." | ( Alexiou, GA; Chousidis, I; Galani, V; Hodaj, E; Kyritsis, AP; Lazari, D; Leonardos, I; Markopoulos, GS; Vartholomatos, E, 2017) |
"Glioblastomas are characterized by amplification of EGFR." | ( Asuthkar, S; Bach, SE; Guda, MR; Lathia, JD; Sahu, K; Tsung, AJ; Tuszynski, J; Velpula, KK, 2017) |
"Glioblastoma is one of the most frequent and aggressive brain tumors." | ( Jin, X; Liu, N; Nie, E; Shi, Z; Wu, W; You, Y; Yu, T; Zhang, J; Zhou, X, 2017) |
"Glioblastoma is the most common and most malignant primary brain tumor with a median survival of 15 months." | ( Alexiou, GA; Galani, V; Hodaj, E; Kyritsis, AP; Lazari, D; Markopoulos, G; Vartholomatos, E, 2017) |
"Backgroud:Glioblastoma is a kind of highly malignant and aggressive tumours in the central nervous system." | ( Cui, H; Dong, Z; Ke, XX; Lei, Q; Yang, L; Yang, R; Yi, L; Zhu, S, 2017) |
"Glioblastoma is the most common and lethal brain tumor associated with only 12% median survival rate of patients." | ( Ranjan, A; Srivastava, SK; Wright, S, 2017) |
"Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year." | ( Gont, A; Hanson, JEL; Kumar, R; Lorimer, IAJ; Perkins, TJ, 2017) |
"Glioblastoma is one of the most frequent primary brain tumours of the central nervous system, with a poor survival time." | ( Chwalibog, A; Grodzik, M; Jaworski, S; Kutwin, M; Sawosz, E; Strojny, B; Wierzbicki, M, 2017) |
"Glioblastoma is the most common and most lethal primary brain cancer." | ( Herrera-Rios, D; Hoerbelt, T; Jiang, T; Kahlert, UD; Koch, K; Li, G; Maciaczyk, D; Maciaczyk, J; Marquardt, V; Ouwens, DM; Pauck, D; Picard, D; Remke, M; Steiger, HJ; Zhang, W; Zhao, L, 2017) |
"Glioblastoma is one of the most malignant and aggressive types of brain tumors." | ( Chaithirayanon, K; Piromkraipak, P; Power, C; Sangpairoj, K; Supavilai, P; Tirakotai, W; Unchern, S; Vivithanaporn, P, 2018) |
"Glioblastoma is the most common primary tumor of the brain and has few long-term survivors." | ( Daniels, DJ; de Mooij, T; Johnson, AJ; Kaptzan, T; Kumar, R; Parney, IF; Peterson, TE, 2017) |
"Glioblastoma is the most common primary CNS malignancy and it is becoming more frequently diagnosed in the elderly population." | ( de Moraes, FY; Laperriere, N, 2017) |
"Glioblastoma is one of the most aggressive malignant primary brain cancer in adults." | ( Cacciatore, I; Ciulla, M; Di Stefano, A; Eusepi, P; Fornasari, E; Marinelli, L; Ozdemir, O; Tatar, A; Turkez, H, 2017) |
"Glioblastoma is a highly lethal brain cancer that frequently recurs in proximity to the original resection cavity." | ( Chai, JN; Chheda, MG; Diamond, MS; Fernandez, E; Gorman, MJ; Hubert, CG; McKenzie, LD; Prager, BC; Rich, JN; Richner, JM; Shan, C; Shi, PY; Tycksen, E; Wang, X; Zhang, R; Zhu, Z, 2017) |
"Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need." | ( Cheng, B; Mito, S; Morales, LD; Tsin, A; Zhang, Y, 2017) |
"Glioblastoma is the most common malignant primary brain tumor, and it is one of the causes of cancer fatality in both adult and pediatric populations." | ( Jiang, Y; Jiao, Y; Li, T; Li, Y; Liu, Y; Wang, D; Wang, Z; Zhao, X, 2017) |
"Glioblastoma is the most aggressive primary brain tumor that originates from the glial cells in adults." | ( Chen, XJ; Li, J; Lv, LJ; Qiao, HB; Zhang, ZM; Zou, CL, 2017) |
"Glioblastoma is the most common and aggressive primary brain tumor and has a high mortality in humans." | ( Jing, D; Shen, L; Yu, H; Zhang, Q; Zhao, Y, 2017) |
"Glioblastoma are highly resistant to radiotherapy and the underlying mechanisms remain unclear." | ( Bache, M; Dehghani, F; Ensminger, S; Ghadban, C; Grabiec, U; Hohmann, T; Vogel, C; Vordermark, D, 2017) |
"Glioblastoma is a highly aggressive brain tumor." | ( Auslander, N; Ben-Shushan, D; Calderón, M; Eldar-Boock, A; Ferber, S; Grossman, R; Haag, R; Henkin, J; Krivitsky, A; Licha, K; Ofek, P; Ram, Z; Ruppin, E; Satchi-Fainaro, R; Scomparin, A; Sousa-Herves, A; Tiram, G; Vossen, LI; Yeini, E, 2017) |
"Glioblastoma is a lethal form of brain tumour usually treated by surgical resection followed by radiotherapy and an alkylating chemotherapeutic agent." | ( Cosgrove, L; Fay, MF; Head, RJ; Martin, JH; Rundle-Thiele, D; Y C Fung, K, 2017) |
"Glioblastoma is the most common and most aggressive form of primary brain tumor in adults and contributes to high social and medical burden as a result of its incurable nature and significant neurologic morbidity." | ( de Groot, JF; Nam, JY, 2017) |
"Glioblastoma is the most common type of primary brain tumor in adults, with high mortality and morbidity rates." | ( Chen, QX; Liao, JM; Liu, BH; Tan, YQ; Yang, JA; Yang, X; Yuan, FE, 2017) |
"Here, we show that glioblastoma are excreting large amounts of branched-chain ketoacids (BCKAs), metabolites of branched-chain amino acid (BCAA) catabolism." | ( Becker, HM; Gaupel, AC; Hell, R; Hiller, K; Kneisel, N; Lichter, P; Nonnenmacher, Y; Poschet, G; Radlwimmer, B; Sapcariu, S; Schlotter, M; Seiffert, M; Silva, LS; Wu, Y, 2017) |
"Glioblastoma is the most common primary brain malignancy and differentiation of true progression from pseudoprogression is clinically important." | ( Choi, SH; Kang, KM; Kim, JH; Lim, WH; Nam, JG; Sohn, CH; Yoo, RE; Yun, TJ, 2017) |
"Glioblastoma is the most common primary malignant brain tumor diagnosed in the USA and is associated with a poor prognosis." | ( Ahluwalia, MS; Braun, K, 2017) |
"Glioblastoma is the most frequent primary brain tumor in adults and a highly lethal malignancy with a median survival of about 15 months." | ( Dhruv, H; Ding, Z; Eschbacher, JM; Kloss, J; Loftus, JC; Peng, S; Pirrotte, P; Roos, A; Tran, NL, 2018) |
"OBJECTIVE Glioblastoma is the most common primary central nervous system tumor in adults." | ( Kaye, AH; Luwor, RB; Mao, L; Morokoff, AP; Paradiso, L; Stylli, SS; Whitehead, CA, 2018) |
"Glioblastoma is the most malignant and lethal subtype brain tumors with high risk of recurrence and therapeutic resistance." | ( Dong, Z; Du, S; Huang, J; Lei, T; Sun, M; Tong, R; Wang, H; Wang, Y; Yang, J; Yang, Y, 2018) |
"Glioblastoma is a common primary brain tumor with aggressive malignancy, which results in poor outcomes, short survival time and high mortality." | ( Chen, H; Jin, X; Li, D; Zhang, G; Zhang, J, 2018) |
"A glioblastoma is a common primary brain tumor that expresses microRNA-21 (miR-21), which inhibits the expression of pro-apoptotic genes such as phosphatase and tensin homologue (PTEN) and programmed cell death 4 (PDCD4)." | ( Jeong, JH; Kim, G; Kim, M; Lee, D; Lee, J; Lee, M; Lee, MS; Oh, J; Piao, C; Tan, X, 2018) |
"Glioblastoma is the most aggressive primary brain tumor with a poor mean survival even with the current standard of care." | ( Johnson, H; White, FM, 2018) |
"Glioblastoma is a devastating malignancy with a dismal survival rate." | ( Bourcier, AJ; Langan, ST; Liao, J; Mrowczynski, OD; Rizk, EB; Specht, CS, 2018) |
"Glioblastoma is a highly malignant disease in critical need of expanded treatment options." | ( Bryant, WM; Dalton, HM; Farmer, G; King, PD; Lehman, NL; Li, X; McElroy, JP; Mifsud, CS; Sak, M; Urio, S; Usubalieva, A; Zumbar, CT, 2018) |
"Glioblastoma is the most frequent and aggressive form of high-grade malignant glioma." | ( Frohnapfel, L; Kaina, B; Quiros, S; Ringel, F; Roos, WP, 2018) |
"Glioblastoma is the most lethal type of primary tumours in the CNS." | ( Emanuelsson, I; Friman, T; Norlin, M; Wikvall, K, 2018) |
"Glioblastoma is a malignant brain tumor that inevitably develops resistance to standard of care drug temozolomide (TMZ) due to a population of cells called cancer stem cells (CSCs)." | ( Chumakova, A; Lathia, JD, 2018) |
"A glioblastoma is a primary CNS tumor that is more aggressive and lethal than other brain tumors." | ( Borges, HL; Clarêncio, J; Costa, SL; da Silva Velozo, E; de Faria Lopes, GP; de J Menezes-Filho, N; de Oliveira, DM; Dos Santos Costa, R; Freire, SM; Moura-Neto, V; Pereira, E; Pitanga, BPS; Rehen, SK; Silva, TCC, 2018) |
"Glioblastoma is the most lethal primary brain tumor and poor survival of glioblastoma patients is attributed to the presence of glioma stem cells (GSCs)." | ( Aderetti, DA; Hira, VVV; Molenaar, RJ; van Noorden, CJF, 2018) |
"Glioblastomas are the most frequently diagnosed and worst primary malignancy of the central nervous system, with very poor prognosis." | ( Fan, L; Gao, Y; He, Y; Meng, H; Sun, L; Xu, B; Xu, H; Zhou, Z, 2018) |
"Glioblastoma is the most common and aggressive glioma, characterized by brain invasion capability." | ( Bonacorso, HG; Costa Nunes, F; Creczynski-Pasa, TB; de Melo, LJ; Feitosa, SC; Martins, MAP; Rode, M; Silva, AH; Silva, LB; Winter, E; Zanatta, N, 2018) |
"Glioblastoma is the most aggressive type of brain cancer with the highest proliferation, invasion, and migration." | ( Chaithirayanon, K; Chongthammakun, S; Parakaw, T; Phuagkhaopong, S; Piromkraipak, P; Srihirun, S; Vivithanaporn, P, 2018) |
"Glioblastoma is the most common and devastating type of malignant brain tumor." | ( Fujimori, H; Fujimoto, K; Ichimura, K; Imamichi, S; Ishikawa, E; Masutani, M; Masutomi, K; Matsumura, A; Matsushita, Y; Matsuzaki, S; Miki, S; Mukasa, A; Narita, Y; Nishikawa, R; Satomi, K; Takahashi, M; Tomiyama, A; Yamamoto, T, 2018) |
"Glioblastoma is the most common malignant brain cancer in adults, with poor prognosis." | ( Azevedo, PO; Birbrair, A; Guerra, DAP; Mintz, A; Paiva, AE; Sena, IFG; Silva, WN, 2018) |
"Glioblastoma is a primary malignant brain tumor with a poor prognosis." | ( Chen, Y; Cheng, YC; Chiu, CY; Kan, PC; Tsao, MJ, 2018) |
"Glioblastoma is the most frequent and aggressive brain tumor due to its high capacity to migrate and invade normal brain tissue." | ( Bastida-Beristain, Y; Camacho-Arroyo, I; Fuente-Granada, M; González-Arenas, A; González-Orozco, JC; Hansberg-Pastor, V; Nicolas-Ortega, W; Valadez-Cosmes, P, 2018) |
"Glioblastomas are a subtype of gliomas, which are the most aggressive and deadly form of brain tumours." | ( Adegoke, AO; Amos, S; Anson, DM; Darkwah, BO; Gryka, RJ; Huseman, ED; Jean-Louis, DS; Lin, S; Paris, RL; Stump, TA; Wilcox, RM, 2018) |
"Glioblastoma is the most frequent and aggressive primary malignant tumor of the central nervous system with a gloomy prognosis." | ( Avril, S; Boury, F; Garcion, E; Hindré, F; Jérôme, C; Lajous, H; Lecomte, P; Lelièvre, B; Riva, R; Tétaud, C, 2018) |
"Glioblastoma is one of the most malignant, angiogenic, and incurable tumors in humans." | ( Abdel Hadi, L; Anelli, V; Beretta, M; Campanella, R; Guarnaccia, L; Marfia, G; Moccia, F; Navone, S; Riboni, L; Tringali, C; Urechie, V, 2018) |
"Glioblastoma is a highly aggressive brain tumor that is characterized by its unparalleled invasiveness." | ( Bernards, R; de Gooijer, MC; Guillén Navarro, M; van Tellingen, O; Wurdinger, T, 2018) |
"Glioblastoma is the most common and aggressive primitive brain tumor in adults." | ( Bellu, L; Bergo, E; Berti, F; Caccese, M; Dal Pos, S; Della Puppa, A; Denaro, L; Gardiman, MP; Lombardi, G; Pambuku, A; Zagonel, V, 2018) |
"Glioblastoma is the worst and most common primary brain tumor." | ( Azambuja, JH; Battastini, AMO; Beckenkamp, LR; Braganhol, E; de Oliveira, FH; Fernandes, MC; Figueiró, F; Gelsleichter, NE; Iser, IC; Scholl, JN; Sévigny, J; Spanevello, RM; Stefani, MA; Teixeira, HF; Wink, MR, 2019) |
"Glioblastoma is the most common malignant brain tumor." | ( Chu, L; Liu, S; Mu, H; Ni, L; Song, Y; Sun, K; Wang, A; Wu, Z; Yan, X; Zhang, C; Zhao, M, 2018) |
"Glioblastoma is the most common malignant brain cancer with a dismal prognosis." | ( Guo, S; Kelly, DF; Liang, Y; Murphy, S; Pham, L; Pridham, KJ; Sheng, Z; Varghese, RT; Young, S, 2018) |
"Glioblastoma are among the most common forms of cancer affecting the central nervous system, and yet there is currently no effective means of treating them." | ( Lin, M; Yao, Z; Zhang, C; Zhao, N, 2019) |
"Glioblastoma is the most common and lethal adult brain tumor." | ( Aldaz, P; Anastasov, N; Atkinson, MJ; Drakulic, D; Garcia, I; Garros-Regulez, L; Marjanovic Vicentic, J; Matheu, A; Nikolic, I; Puskas, N; Raicevic, S; Sampron, N; Stevanovic, M; Tasic, G; Vukovic, V, 2019) |
"Glioblastoma is one of the most aggressive forms of cancers and has a poor prognosis." | ( Akiyama, T; Echizen, K; Funato, K; Hayashi, T; Ino, Y; Koyama-Nasu, R; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Negishi, L; Saito, N; Shimizu, N; Tabar, V; Todo, T, 2018) |
"Glioblastoma is the most common and lethal intracranial tumor type, characterized by high angiogenic and infiltrative capacities." | ( Bian, B; Han, L; Hayashi, H; Shimada, R; Si, N; Takagi, N; Yuan, B; Zhao, HY, 2018) |
"Glioblastoma is the most common and aggressive primary brain tumor in adults." | ( Chen, X; Han, D; Hou, X; Liu, H; Liu, Z; Ma, J; Peng, F; Shen, C; Shu, M; Wang, K; Wang, L; Wang, X; Wu, J; Yang, G; Yin, Z; Zhang, D; Zhao, B; Zhao, S; Zhao, W; Zheng, Z; Zhong, C, 2018) |
"Glioblastoma are highly immunosuppressive brain tumors that are known for their T cell paucity." | ( Bergers, G; Vella, G, 2018) |
"Glioblastoma is a highly malignant tumor that easily acquires resistance to treatment." | ( Bae, SH; Gwak, H; Han, SS; Jang, H; Jeon, JH; Kang, SG; Kim, DK; Kim, HY; Kim, JK; Kim, SY; Kim, YH; Lee, BI; Lee, JH; Shim, JK; Shin, DH; You, HJ, 2018) |
"Although glioblastomas are heterogeneous brain-infiltrating tumors, their treatment is mostly focused on the contrast-enhancing tumor mass." | ( Amit-Yousif, AJ; Barger, GR; Bosnyák, E; John, F; Juhász, C; Klinger, NV; Michelhaugh, SK; Mittal, S; Robinette, NL; Shah, KD, 2019) |
"Glioblastoma is one of the most rapaciously growing cancer within the brain with an average lifespan of 12-15 months (5-year survival <3-4%)." | ( Gondaliya, P; Kalia, K; Muniswamy, VJ; Raval, N; Tambe, V; Tekade, RK, 2019) |
"Glioblastomas are rich in blood vessels (i." | ( Ameratunga, M; Grant, R; Khasraw, M; Pavlakis, N; Simes, J; Wheeler, H, 2018) |
"Glioblastoma is a highly vascularised tumour and there are few treatment options after disease recurrence." | ( Bellu, L; Brandes, AA; Daniele, B; De Salvo, GL; Eoli, M; Faedi, M; Farina, M; Gardiman, MP; Indraccolo, S; Lolli, I; Lombardi, G; Magni, G; Pace, A; Pambuku, A; Pasqualetti, F; Rizzato, S; Rudà, R; Soffietti, R; Zagonel, V, 2019) |
"Glioblastoma is the most frequent primary malignant brain tumor." | ( Amelot, A; Bauchet, F; Bauchet, L; Bessaoud, F; Charissoux, M; Darlix, A; Duffau, H; Fabbro, M; Fabbro-Peray, P; Figarella-Branger, D; Mandonnet, E; Mathieu-Daude, H; Pallud, J; Rigau, V; Riondel, A; Sorbets, E; Taillandier, L; Tretarre, B; Zouaoui, S, 2019) |
"Glioblastoma is the most common type of primary brain tumour in adults, and its pathogenesis is particularly complicated." | ( Chen, QX; Liao, JM; Liu, BH; Liu, JH; Xu, PF; Yang, JA; Yang, X; Yuan, FE, 2019) |
"Human glioblastoma is a malignant and aggressive primary human brain solid tumor characterized by severe hypoxia." | ( He, X; Huang, S; Li, F; Qi, P; Zhang, T, 2019) |
"Glioblastoma is the most malignant and widespread brain tumor in adults, with a rapid clinical course." | ( Aprile, C; Cavagnini, M; Ciocca, M; Facoetti, A; Lodola, L; Marenco, M; Nano, R; Orecchia, R; Pasi, F; Persico, MG; Valvo, F, 2019) |
"Glioblastoma is the most common and most aggressive primary brain tumor, has high mortality, and affects both children and adults." | ( Krichevsky, AM; Uhlmann, EJ, 2019) |
"Glioblastoma is the leading malignant glioma with a poor prognosis." | ( Matsuda, R; Morita, H; Motoyama, Y; Murakami, T; Nakagawa, I; Nakamura, M; Nakase, H; Nakazawa, T; Nishimura, F; Omoto, K; Shida, Y; Tanaka, Y; Tsujimura, T, 2019) |
"Glioblastoma is the most fatal type of primary brain cancer, and current treatments for glioblastoma are insufficient." | ( Chern, JW; Hsin, LW; Hung, PY; Liu, JR; Yu, CW, 2019) |
"Glioblastoma is the most common and malignant brain tumor, and current therapies confer only modest survival benefits." | ( Berg, HE; Hvinden, IC; Lundanes, E; Rise, F; Sachse, D; Sandberg, CJ; Skaga, E; Skottvoll, FS; Vik-Mo, EO; Wilson, SR, 2019) |
"The treatment of glioblastoma is a critical health issue, owing to its resistance to chemotherapy." | ( Bureta, C; Komiya, S; Maeda, S; Nagano, S; Saitoh, Y; Sasaki, H; Setoguchi, T; Taniguchi, N; Tokumoto, H, 2019) |
"The prognosis of glioblastoma is still dismal." | ( Panaro, MA; Porro, C; Prifti, E; Trotta, T, 2019) |
"Glioblastoma is the most invasive form of brain tumor." | ( Arora, A; Somasundaram, K, 2019) |
"Glioblastoma is a disease with high heterogeneity that has long been difficult for doctors to identify and treat." | ( Chen, X; Gao, M; Liu, Z; Shu, M; Wang, K; Wang, X; Ye, J; Yin, Z; Zhao, B; Zhao, H; Zhao, S; Zhao, W; Zheng, Z; Zhong, C, 2019) |
"Glioblastoma is one of the most devastating human malignancies for which a novel efficient treatment is urgently required." | ( Fujimoto, K; Fukuoka, K; Hamada, A; Hayashi, M; Ichimura, K; Kikuchi, K; Maida, Y; Masutomi, K; Matsushita, Y; Miki, S; Mukasa, A; Narita, Y; Nishikawa, R; Shinkyo, R; Takahashi, M; Tamura, K; Yasukawa, M, 2019) |
"Glioblastoma is a highly aggressive and treatment resistant primary brain tumor." | ( Devraj, K; Dubinski, D; Hattingen, E; Peters, KG; Plate, KH; Reiss, Y; Seifert, V; Senft, C, 2019) |
"Glioblastoma is a high-grade glioma with poor prognosis even after surgery and standard therapy." | ( Faust, H; Gaunitz, F; Meixensberger, J; Oppermann, H; Yamanishi, U, 2019) |
"Glioblastoma is a hostile brain tumor associated with high infiltration leading to poor prognosis." | ( Dos Santos Rodrigues, B; Lakkadwala, S; Singh, J; Sun, C, 2019) |
"Glioblastoma is a grade IV malignant glioma with high recurrence and metastasis and faces a therapeutic obstacle that the blood-brain barrier (BBB) severely hinders the brain entry and efficacy of therapeutic drugs." | ( Chen, L; Chu, X; Gao, Z; Guan, Y; Huang, W; Jin, M; Liu, X; Meng, L; Xin, X; Xing, H, 2019) |
"Glioblastoma is the most common, malignant and devastating type of primary brain tumor." | ( Cha, Z; Cheng, J; He, Y; Jia, J; Peng, Z; Qin, J; Xiang, H; Yu, H, 2019) |
"Glioblastoma is the most common primary brain tumor in adults." | ( Al-Omaishi, S; Celebre, A; Chan, J; Das, S; Dirks, PB; Ghannad-Zadeh, K; Guan, J; Isaev, K; Kaskun, O; Moran, MF; Morrissy, AS; Munoz, DG; Reimand, J; Sachdeva, R; Smiljanic, S; Taylor, MD; Tong, J; Wilson, TM; Wu, M, 2019) |
"Glioblastoma is the most aggressive and most lethal primary brain tumor in the adulthood." | ( Antoccia, A; Berardinelli, F; Buccarelli, M; di Masi, A; Leone, S; Mancuso, M; Muoio, D; Pallini, R; Ricci-Vitiani, L; Tanori, M, 2019) |
"Glioblastoma is the most common and malignant primary brain tumour in adults, with a dismal prognosis." | ( Ashkan, K; Briscoe, AG; Burton, G; Hargreaves, IP; Heales, SJ; Holt, WV; Jung, J; Keatley, K; Littlewood, DTJ; McGeehan, JE; McGeehan, RE; Meunier, B; Pilkington, GJ; Rajala, N; Stromei-Cleroux, S; Wiltshire, T, 2019) |
"Chemoresistance in glioblastoma is largely attributed to repair of temozolomide-induced DNA lesions by O6-methylguanine-DNA methyltransferase (MGMT)." | ( Chen, Z; Deng, S; Guo, M; Huang, G; Lei, B; Li, Y; Li, Z; Liu, Y; Pan, J; Qi, S; Wang, H; Xiang, W; Yi, GZ; Yu, L; Zhang, X, 2019) |
"Glioblastoma is a highly malignant brain tumor with poor prognosis and survival rate because of a lack of effective diagnostic methods." | ( An, X; Chen, J; Feng, S; Gu, T; Jiang, Q; Meng, X; Ning, X; Shan, X; Zhang, J; Zhang, L, 2019) |
"Glioblastoma is a lethal brain tumor, heavily infiltrated by tumor-associated myeloid cells (TAMCs)." | ( Anderson, CJ; Edinger, RS; Edwards, WB; Kohanbash, G; Kumar, R; Kurland, BF; McCarl, L; Nigam, S; Panigrahy, A, 2020) |
"Glioblastoma is the most common and uncompromising primary brain tumour and is characterized by a dismal prognosis despite aggressive treatment regimens." | ( Chen, Z; Duffy, A; Hambardzumyan, D; Herting, CJ; Maximov, V; Shayakhmetov, DM; Szulzewsky, F, 2019) |
"Glioblastoma is the brain tumor with the worst prognosis." | ( Erices, JI; Niechi, I; Quezada, C; Richter, HG; Rocha, JD; San Martín, R; Silva, P; Torres, Á; Uribe, D; Uribe-Ojeda, A, 2019) |
"Glioblastoma is the most common and deadly type of brain cancer." | ( Chen, JY; Su, BC, 2020) |
"Glioblastoma is the most common primary malignant tumor of the central nervous system, most of which occur in the brain." | ( Kuang, A; Ma, H; Pan, L; Shen, G; Su, M, 2020) |
"Glioblastoma is the most common type of malignant brain tumor." | ( Bai, Y; Chen, Y; Ge, J; Jiang, S; Li, W; Ren, J; Wang, X; Wu, B; Xu, H; Zhao, G; Zhong, S, 2019) |
"Glioblastoma is a devastating tumor affecting the central nervous system with infiltrative capacity, high proliferation rate and chemoresistance." | ( Azambuja, JH; Bona, NP; Braganhol, E; da Silveira, EF; de M Meine, B; de Oliveira, FH; Gelsleichter, NE; Mendonça, LT; Pedra, NS; Sekine, FG; Soares, MSP; Spanevello, RM; Spohr, L; Stefanello, FM, 2020) |
"Since glioblastoma is a highly lethal and fast-growing brain tumor, new therapeutic strategies are urgently needed." | ( Ascari, LM; Cordeiro, Y; Faria, BM; Romão, LF; Soares, AG; Soares, JM; Souza, JM, 2019) |
"Glioblastoma is one of the most common brain tumors with high invasion and malignancy." | ( Asemi, Z; Neamati, F, 2020) |
"The treatment of glioblastoma is challenging for the clinician, due to its chemotherapeutic resistance." | ( Dunbar, GL; Maiti, P; Plemmons, A, 2019) |
"Glioblastoma is the most frequent and lethal primary brain tumor." | ( Berens, ME; Burns, TC; Califano, A; Carlson, BL; Caron, A; Decker, PA; Dhruv, HD; Eckel-Passow, JE; Evers, L; Giannini, C; Grove, R; Jenkins, RB; Kitange, GJ; Klee, EW; Kollmeyer, TM; LaChance, DH; Ma, DJ; Marin, BM; Meyer, FB; Mladek, AC; O'Neill, BP; Parney, IF; Peng, S; Remonde, D; Sarkar, G; Sarkaria, JN; Schroeder, MA; Sulman, EP; Tian, S; Tran, NL; Vaubel, RA; Verhaak, RG; Wang, Q; Yan, H, 2020) |
"Glioblastoma is uncommon in pediatric patients and particularly those with primitive neuronal components." | ( Kay, MD; Kuo, PH; Pariury, HE; Perry, A; Winegar, BA, 2020) |
"Glioblastoma is the most malignant and prevalent brain tumor in adults." | ( Khathayer, F; Ray, SK; Taylor, MA, 2020) |
"Glioblastoma is an aggressive central nervous system tumor with a 5-year survival rate of < 10%." | ( Hirose, Y; Ohba, S, 2020) |
"Glioblastoma is the most aggressive brain tumor characterized by diffuse infiltration into the normal brain parenchyma." | ( Iwasawa, C; Mine, Y; Miyoshi, H; Morimoto, Y; Oishi, Y; Okano, H; Sampetrean, O; Saya, H; Tamura, R; Toda, M; Yoshida, K, 2020) |
"Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance." | ( Chen, J; Chen, L; Hao, B; He, M; Li, X; Wang, C; Wu, H; Zhang, G; Zhang, T, 2020) |
"Glioblastomas are the most aggressive type of brain tumour, with poor prognosis even after standard treatment such as surgical resection, temozolomide and radiation therapy." | ( Chiang, IT; Hsu, FT; Wang, WS, 2020) |
"Glioblastoma is the deadliest neoplasm with the worst 5-year survival rate among all human cancers." | ( Lee, JE; Lee, JW; Moon, EY; Yoon, SS, 2020) |
"Glioblastoma is one of the most difficult cancers to treat with a 5-year overall survival rate less than 5%." | ( Fang, F; Ji, Y; Li, H; Lu, Y; Qiu, P; Tang, H; Zhang, S, 2020) |
"Pediatric glioblastomas are known to be one of the most dangerous and life-threatening cancers among many others regardless of the low number of cases reported." | ( Al-Youbi, AO; Bashammakh, AS; El-Shahawi, MS; Graham, RM; Leblanc, RM; Liyanage, PY; Vanni, S; Zhou, Y, 2020) |
"Glioblastoma is the most aggressive central nervous system (CNS) neoplasm with high proliferation and tissue invasion capacity and is resistant to radio and chemotherapy." | ( da Silva Marques, M; de Moraes Vaz Batista Filgueira, D; de Souza Votto, AP; Horn, AP; Lettnin, AP; Marinho, MAG, 2021) |
"Glioblastomas are generally incurable partly because monocytes, macrophages, and microglia in afflicted patients do not function in an antitumor capacity." | ( Bose, P; Dunn, JF; Kelly, J; Mirzaei, R; Mishra, MK; Poon, C; Rawji, K; Sarkar, S; Yang, R; Yong, VW; Zemp, FJ, 2020) |
"Glioblastoma is a rapidly proliferating tumor." | ( Glas, M; Grosu, AL; Guberina, M; Guberina, N; Hau, P; Jabbarli, R; Jendrossek, V; Kebir, S; Lazaridis, L; Lübcke, W; Lüdemann, L; Niessen, M; Nour, Y; Oster, C; Pierscianek, D; Pöttgen, C; Scharmberg, C; Scheffler, B; Schmidt, T; Stuschke, M; Sure, U, 2020) |
"Glioblastoma is a malignant brain tumor exhibiting highly aggressive proliferation and invasion capacities." | ( Hanashima, Y; Hara, H; Nakayama, T; Ozawa, Y; Sano, E; Sumi, K; Tatsuoka, J; Ueda, T; Yagi, C; Yamamuro, S; Yoshimura, S; Yoshino, A, 2020) |
"Glioblastoma is the most common primary malignant brain tumor." | ( Aldape, K; Butler, M; Pommier, Y; Pongor, L; Quezado, M; Raffeld, M; Su, YT; Trepel, J; Wu, J; Xi, L, 2020) |
"Glioblastoma is the most common primary brain tumor; survival is typically 12-18 months after diagnosis." | ( Moore, D; Padilla, F; Sheehan, D; Sheehan, J; Sheehan, K; Sulaiman, M; Xu, Z, 2020) |
"Glioblastoma is one of the most aggressive tumors of the central nervous system." | ( Ghayour Mobarhan, M; Ghorbani, A; Jaliani, HZ; Lotfi, M; Sadeghnia, HR; Shahcheraghi, SH; Soukhtanloo, M, 2021) |
"Glioblastomas are the most common malignant primary intrinsic brain tumors." | ( Le Rhun, E; Weller, M, 2020) |
"Glioblastoma is the most devastating primary brain tumor and effective therapies are not available." | ( Azambuja, JH; Battastini, AMO; Beckenkamp, LR; Braganhol, E; de Oliveira, FH; Gelsleichter, NE; Lenz, GS; Michels, LR; Schuh, RS; Stefani, MA; Teixeira, HF; Wink, MR, 2020) |
"Glioblastoma is the most common primary malignant brain tumor in adults." | ( Buelow, KL; Chinnaiyan, P; Graham, SF; Guastella, AR; Kant, S; Kesarwani, P; Kumar, P; Nakano, I, 2020) |
"Glioblastoma is the most common malignant tumor of the brain, but its treatment outcomes can be improved by new therapeutic techniques using biocompatible materials." | ( Belousov, A; Khotimchenko, Y; Kovalev, V; Kumeiko, V; Malykin, G; Shved, N; Suprunova, I; Titov, S, 2020) |
"Glioblastoma is one of the most aggressive human brain tumors." | ( Bryukhovetskiy, A; Bryukhovetskiy, I; Gulaia, V; Khotimchenko, R; Lyakhova, I; Piatkova, M; Romanishin, A; Sharma, A; Sharma, HS; Shmelev, M, 2020) |
"Glioblastoma is the most common malignant primary brain tumor." | ( Ashley, DM; Friedman, HS; Khasraw, M; López, GY; Malinzak, M; Tan, AC, 2020) |
"Glioblastoma is the most common primary brain tumor with poor survival rate and without effective treatment strategy." | ( Chen, WT; Chung, JG; Hsu, FT; Wu, CT, 2020) |
"Glioblastoma is a highly invasive tumor, in which CCL5 expression correlates with shorter patient survival." | ( Breznik, B; Hrastar, B; Koprivnikar Krajnc, M; Lah Turnšek, T; Majc, B; Mlakar, J; Mlinar, M; Novak, M; Pestell, RG; Porčnik, A; Rotter, A; Stare, K, 2020) |
"Glioblastoma is the most aggressive primary brain tumor leading to death in most of patients." | ( Bardiès, M; Belluco, S; Bonnefont-Rebeix, C; Brown, R; Buronfosse, T; Carozzo, C; Gehan, H; Khoshnevis, M; Louis, C; Marcon, L; Nennig, C; Ponce, F; Roger, T; Tillement, O; Zahi, I, 2020) |
"Glioblastoma is characterized by the extensive vascularization with poor prognosis." | ( Bao, K; Chen, L; Huang, C; Peng, T; Wan, W; Yang, X; Zhang, X, 2020) |
"Glioblastoma is an extremely aggressive glioma, resistant to radio and chemotherapy usually performed with temozolomide." | ( Arrais-Neto, AM; Carballo, GB; Matias, D; Pessoa, LS; Ribeiro, JH; Spohr, TCLSE, 2020) |
"Glioblastoma is a common, malignant brain tumor whose disease incidence increases with age." | ( Ahnert, P; Holland, H; Johnson, AA; Kirsten, H; Krupp, W; Meixensberger, J; Mueller, W; Richter, M; Rohani, L; Rudolf, D; Schmidt, C; Schulz, RM; Wallenborn, M; Xu, LX, 2020) |
"Glioblastoma is the most common primary malignant tumor of the central nervous system which is the most lethal type of primary brain tumor in adults with the survival time of 12-15 months after the initial diagnosis." | ( Ahmadi-Zeidabadi, M; Ashta, A; Motalleb, G, 2020) |
"Glioblastoma is devastating cancer with a high frequency of occurrence and poor survival rate and it is urgent to discover novel glioblastoma-specific antigens for the therapy." | ( Liu, C; Liu, R; Lu, Y; Zhang, F; Zhang, H, 2020) |
"Glioblastoma is the most aggressive central nervous system tumour." | ( Alamón, C; Cabral, P; Cerecetto, H; Couto, M; Dagrosa, MA; Nievas, S; Perona, M; Teixidor, F; Viñas, C, 2020) |
"Glioblastoma is a primary brain tumor with a poor prognosis despite multimodal therapy including surgery, radiotherapy and alkylating chemotherapy." | ( Mason, WP; Richardson, PG; Roth, P; Weller, M, 2020) |
"Glioblastoma is one of the most common and most aggressive brain cancers." | ( Cheng, AY; Chien, YC; Hsieh, YH; Lee, HC; Yu, YL, 2020) |
"Glioblastoma is a fast-growing primary brain tumor observed in adults with the worst prognosis." | ( Aldanan, S; Alghareeb, WA; Alhussain, H; AlNajjar, FH; Alsaeed, E; Alsharm, AA; Altwairgi, AK; Balbaid, AAO; Orz, Y, 2021) |
"Glioblastoma is the most aggressive form of primary brain cancer, with a median survival of 12-15 months." | ( Drill, M; Hamilton, JA; Jones, NC; Kan, LK; Monif, M; O'Brien, TJ; Powell, KL, 2020) |
"Glioblastomas are the most frequent and aggressive form of primary brain tumors with no efficient cure." | ( Jensen, ON; Karatsai, O; Rędowicz, MJ; Shliaha, P; Stasyk, O, 2020) |
"Glioblastoma is a malignant brain tumour with a median survival of 14." | ( Clarke, PA; Fay, M; Lovato, T; Marlow, M; McCrorie, P; Mistry, J; Rahman, R; Ritchie, AA; Smith, SJ; Taresco, V; Ward, I, 2020) |
"Glioblastoma is an aggressive, fast-growing brain tumor influenced by the composition of the tumor microenvironment (TME) in which mesenchymal stromal cell (MSCs) play a pivotal role." | ( Giacomelli, C; Marchetti, L; Martini, C; Pietrobono, D; Trincavelli, ML, 2020) |
"In particular, glioblastoma is one of the most lethal brain tumors." | ( Fermi, V; Herold-Mende, C; Roesch, S; Romero-Nieto, C; Rominger, F, 2020) |
"Glioblastoma is the most common and aggressive type of brain tumor with high recurrence and fatality rates." | ( Aoki, T; Hara, A; Hirono, S; Ihara, F; Iwadate, Y; Kobayashi, M; Koyama-Nasu, R; Matsutani, T; Motohashi, S; Nakayama, T; Takami, M; Toyoda, T, 2021) |
"Glioblastoma is the most frequent aggressive primary brain tumor amongst human adults." | ( Arús, C; Candiota, AP; Julià-Sapé, M; Ledesma-Carbayo, MJ; Núñez, LM; Romero, E; Santos, A; Vellido, A, 2020) |
"Glioblastoma is the most common and aggressive type of cancer in the brain; its poor prognosis is often marked by reoccurrence due to resistance to the chemotherapeutic agent temozolomide, which is triggered by an increase in the expression of DNA repair enzymes such as MGMT." | ( Barnes, S; Burma, S; Buszczak, M; Conacci-Sorrell, M; Han, J; Kanji, S; Kilgore, JA; Lafita-Navarro, MC; Venkateswaran, N; Williams, NS, 2020) |
"Glioblastoma is the most severe form of brain cancer." | ( Caputto, BL; Caverzán, MD; Milla Sanabria, LN; Palacios, RE; Prucca, CG; Rivarola, VA; Rodríguez, LB; Vilchez, ML, 2021) |
"Glioblastoma is the most common and the deadliest brain cancer." | ( Cielecka-Piontek, J; Kaczmarek, M; Kleszcz, R; Krajka-Kuźniak, V; Majchrzak-Celińska, A; Paluszczak, J; Studzińska-Sroka, E; Wierzchowski, M; Zielińska-Przyjemska, M, 2021) |
"Glioblastoma is a type of aggressive brain tumor that grows very fast and evades surrounding normal brain, lead to treatment failure." | ( Kim, DH; Kim, YN; Koo, KH; Lee, CH; Lee, EJ; Park, J; Park, JB; Shim, J; Sung, JY, 2020) |
"Glioblastoma is the most common malignant tumor of the central nervous system and is treated with a combination of surgery, radiation and chemotherapy." | ( Kaji, T; Kitabatake, K; Tsukimoto, M, 2021) |
"Glioblastoma is a severe type of brain tumor with a poor prognosis and few therapy options." | ( Andrade Tomaz, M; de Souza, I; Karolynne Seregni Monteiro, L; Menck, CFM; Molina Silva, M; Reily Rocha, A; Rocha, CRR; Rodrigues Gomes, L; Teatin Latancia, M, 2020) |
"Glioblastoma is a highly malignant brain tumor with limited treatment options and short survival times." | ( Efferth, T; Giordano, FA; Greten, HJ; Kadioglu, O; Mayr, K; Saeed, MEM; Wenz, F; Yildirim, A, 2021) |
"Glioblastoma is one of the leading cancer-related causes of death of the brain region and has an average 5-year survival rate of less than 5%." | ( Chen, CJ; Chung, YH; Hsu, LS; Yeh, LT, 2020) |
"Glioblastoma is the most lethal tumor of the central nervous system, presenting a very poor prognostic, with a survival around 16 months." | ( Amaral da Silva, VD; Costa, SL; da Silva, KC; David, JM; David, JP; de Faria Lopes, GP; de Fátima Costa, M; Dos Santos, BL; Moura-Neto, V; Nascimento, RP; Oliveira, MDN; Ulrich, H, 2021) |
"Glioblastoma is the most common lethal malignant intracranial tumor with a low 5-year survival rate." | ( Dong, CY; Hong, S; Huang, QX; Liu, FS; Zhang, XZ; Zheng, DW; Zhong, ZL, 2021) |
"Glioblastoma is one of the most invasive tumors of the central nervous system, and has a high degree of malignancy and poor prognosis." | ( Guo, CY; Hu, P; Jiang, QG; Kuang, H; Lv, YX; Xiao, ZM; Zhang, WH; Zhu, YG, 2021) |
"Glioblastoma is the deadliest brain tumor in adults, and the standard of care consists of surgery followed by radiation and treatment with temozolomide." | ( Bensinger, SJ; Bhat, K; Cheng, F; Cloughesy, TF; He, L; Ioannidis, A; Kornblum, HI; Liau, LM; Nathanson, D; Nghiemphu, PL; Pajonk, F; Saki, M; Tsang, J; Zhang, L, 2021) |
"Glioblastoma is the most aggressive cancer among primary brain tumours." | ( Bošnjak, R; Breznik, B; Lah, TT; Majc, B; Marinelli, O; Mlinar, M; Nabissi, M; Novak, M; Pena Almidon, MA; Zomer, R; Žvar Baškovič, B, 2021) |
"Glioblastoma is characterized by the robust infiltration of immunosuppressive tumor-associated myeloid cells (TAMCs)." | ( Burga, R; Burns, M; Castro, B; Chandel, NS; Cordero, A; Gao, P; Han, Y; Horbinski, CM; Hou, D; Lee-Chang, C; Lesniak, MS; Lopez-Rosas, A; Miska, J; Rashidi, A; Reshetnyak, YK; Sampat, S; Stoolman, JS; Xiao, T; Zhang, P, 2021) |
"Glioblastoma is the most malignant brain tumor and presents high resistance to chemotherapy and radiotherapy." | ( Castresana, JS; De La Rosa, J; Idoate, MA; Meléndez, B; Rey, JA; Urdiciain, A; Zazpe, I; Zelaya, MV, 2021) |
"Glioblastoma is the most common primary malignant brain tumor that is usually considered fatal even with treatment." | ( Chang, KY; Chien, CH; Chuang, JY; Hsueh, WT, 2021) |
"Glioblastoma is an aggressive form of brain cancer." | ( Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Howell, A; Jefferies, S; Kelly, C; Kernohan, A; Kurian, KM; McAleenan, A; Robinson, T; Schmidt, L; Spiga, F; Vale, L; Wragg, C, 2021) |
"Glioblastoma is the most common malignant brain tumor, currently treated by surgery followed by concomitant radiotherapy and temozolomide-based chemotherapy." | ( Chabardès, S; Fulbert, C; Ratel, D, 2021) |
"Glioblastoma is the most common malignant primary brain tumor." | ( Bello-Alvarez, C; Camacho-Arroyo, I, 2021) |
"Glioblastoma is the most common primary brain tumor and remains uniformly fatal, highlighting the dire need for developing effective therapeutics." | ( Boockvar, J; Brahmbhatt, H; Gao, S; Gonzalez, C; Jamil, E; Khan, MB; MacDiarmid, J; Mugridge, N; Ruggieri, R; Sarkaria, JN; Symons, M; Tran, NL, 2021) |
"Glioblastoma is the most aggressive and common intracranial malignant tumor, and the prognosis is still poor after various treatments." | ( Guo, Y; Jia, M; Song, Y; Sun, Y; Wang, Y; Yu, P; Zhao, L, 2021) |
"Glioblastomas are the most common and aggressive primary brain tumors in adults, and patients with glioblastoma have a median survival of 15 months." | ( Bello-Alvarez, C; Camacho-Arroyo, I; González-Arenas, A; Moral-Morales, AD, 2021) |
"Glioblastoma is a primary brain cancer with a near 100% recurrence rate." | ( Ahmed, AU; Ali, ES; Atashi, F; Baisiwala, S; Ben-Sahra, I; Horbinski, CM; James, CD; Kumthekar, P; Lee, G; Lesniak, MS; Miska, J; Park, CH; Saathoff, MR; Savchuk, S; Shireman, JM; Stupp, R, 2021) |
"Glioblastoma is the most malignant tumor of the brain associated with poor prognosis and outcome, and hence there is an urgent need to develop novel treatments for glioblastoma." | ( de Vega, S; Hara, H; Inoue, S; Nakamura, S; Okada, Y; Shimazawa, M; Tsuji, S; Yamada, T, 2021) |
"Glioblastoma is the most common and aggressive type of malignant brain tumor with poor survival and limited therapeutic options." | ( Ge, C; Li, J; Liu, HK; Liu, L; Qian, Y, 2021) |
"Glioblastoma is the most frequently diagnosed type of primary brain tumour in adults." | ( Collis, SJ; Rominiyi, O, 2022) |
"The progression of glioblastomas is associated with a variety of neurological impairments, such as tumor-related epileptic seizures." | ( Hörnschemeyer, J; Kirschstein, T; Lange, F, 2021) |
"Glioblastoma is a high-grade glial neoplasm with a patient survival of 12-18 months." | ( Bates, SJ; Bianchetti, E; Nguyen, TTT; Roth, KA; Siegelin, MD, 2021) |
"Glioblastoma is the most common primary malignancy of the central nervous system with a dismal prognosis." | ( Alhalabi, OT; Baumgartner, U; Day, BW; Fletcher, MNC; Goidts, V; Göttmann, M; Hai, L; Hansen-Palmus, L; Herold-Mende, C; Hielscher, T; Kessler, T; Lokumcu, T; Nakano, I; Phillips, E; Puccio, L; Rahman, S; Sahm, F; Schlue, S; Wick, W; Wittmann, E, 2022) |
"Most recurrent glioblastomas are temozolomide resistant." | ( Chang, YW; Chen, CY; Chen, YC; Hsu, JB; Huang, SW; Kuo, DP; Lee, GA; Li, YT; Lin, WL, 2021) |
"Glioblastoma is a malignant brain tumor with poor prognosis that rapidly acquires resistance to available clinical treatments." | ( Chien, CL; Liao, ML; Luo, EW, 2021) |
"Glioblastoma is a highly malignant brain tumor with no curative treatment options, and immune checkpoint blockade has not yet shown major impact." | ( Bachmann, F; Dietrich, PY; Espinoza, FI; Genoud, V; Lane, HA; Marinari, E; McSheehy, P; Rochemont, V; Walker, PR, 2021) |
"Glioblastoma is a lethal neoplasm with few effective therapy options." | ( Gao, Y; Ji, J; Liu, A; Qiu, N; Xi, Y; Xu, J; Yang, X; Zhai, G, 2021) |
"Glioblastoma is the most common primary brain malignancy and carries with it a poor prognosis." | ( Camphausen, K; Degorre, C; Mathen, P; Tofilon, P, 2021) |
"Glioblastoma is the most common primary malignant brain tumor with an incidence of 5/100,000 inhabitants/year and a 5-year survival rate of 6." | ( Baloglu, S; Cebula, H; Chibbaro, S; De Mathelin, M; Gangi, A; Mallereau, CH; Noblet, V; Noel, G; Proust, F; Todeschi, J, 2022) |
"Glioblastoma is the most serious type of brain cancer with poor prognosis." | ( Li, J; Wang, N; Xin, Q; Xu, N, 2021) |
"Glioblastoma is the most life-threatening tumour of the central nervous system." | ( Alves-Leon, SV; Campanati, L; Eugenio, M; Marcondes de Souza, J; Müller, N; Romão, LF; Sant'Anna, C, 2021) |
"Glioblastoma is the most common and most aggressive primary brain cancer in adults." | ( Burgess, C; FitzJohn, T; Kaye, AH; O'Rawe, M; Pandey, R; Sim, D; Tan, ST; Wickremesekera, AC; Young, D, 2022) |
"Glioblastoma is the most common intracranial primary malignant tumor, which leads to the poor quality of life of patients and has a high recurrence rate." | ( Cui, HJ; Lu, XY; Wan, SC; Wang, ZZ; Zhao, EH, 2021) |
"Glioblastoma is the most frequent and malignant primary brain tumor." | ( Becker, A; Burger, MC; Clusmann, H; Delev, D; Giordano, FA; Glas, M; Goldbrunner, R; Grauer, O; Güresir, E; Hau, P; Heiland, DH; Herrlinger, U; Krex, D; Nemeth, R; Potthoff, AL; Radbruch, A; Sabel, M; Schaub, C; Schilling, J; Schlegel, U; Schmid, M; Schneider, M; Schnell, O; Schuss, P; Seidel, C; Steinbach, JP; Tabatabai, G; Thon, N; Vatter, H; Weller, J; Winkler, F; Zeyen, T, 2022) |
"Glioblastoma is the central nervous system tumor with the highest mortality rate, and the clinical effectiveness of chemotherapy is low." | ( Cao, Y; Cheng, B; Gao, D; Hong, X; Qin, D; Wang, L; Zhou, H, 2022) |
"Glioblastoma is the commonest primary brain cancer in adults whose outcomes are amongst the worst of any cancer." | ( Akkari, L; Borst, GR; Coope, DJ; McBain, C; O'Connor, J; Quinones-Hinojosa, A; Trifiletti, DM; Waqar, M, 2022) |
"Glioblastoma is the most common and lethal malignant brain tumor." | ( Bruinsmann, FA; de Cristo Soares Alves, A; de Fraga Dias, A; Figueiró, F; Lopes Silva, LF; Raffin Pohlmann, A; Sonvico, F; Stanisçuaski Guterres, S; Visioli, F, 2022) |
"Glioblastoma is the most common and fatal primary malignant tumor in the central nervous system, and the prognosis is poor." | ( Chen, J; Liang, RS; Liu, S; Wang, CH; Zhang, Q; Zhuang, BB; Zhuang, YD, 2022) |
"Glioblastomas are the most aggressive brain tumors for which therapeutic options are limited." | ( Carson, SC; Colley, SB; Faia, C; Ingraham Iv, CH; Jursic, BS; Lassak, A; Peruzzi, F; Plaisance-Bonstaff, K; Reiss, K; Stalinska, J; Vittori, C, 2022) |
"Glioblastoma is a highly aggressive brain tumor characterized by high recurrence and poor prognosis." | ( Huang, J; Su, F; Xu, L; Zhong, X; Zhou, Y, 2022) |
"In humans, glioblastoma is the most prevalent primary malignant brain tumor." | ( Gigli, G; Leporatti, S; Persano, F, 2022) |
"Glioblastoma is one of the deadliest malignant gliomas." | ( Hacioglu, C; Kar, F, 2023) |
"Glioblastoma is a deadly cancer tumor in the brain and has a survival rate of about 15 months." | ( Jang, WI; Jeong, HJ; Jung, CW; Kim, EH; Kim, HJ; Kim, JY; Lee, WS; Park, MJ, 2022) |
"Glioblastoma is the most prevalent and aggressive tumor subtype of glioma." | ( Alyautdin, R; Chubarev, V; Grigorevskikh, E; Ismail, N; Merkulov, V; Petrenko, D; Smolyarchuk, E; Sologova, S; Syzrantsev, N, 2022) |
"Glioblastoma is the most aggressive form of brain cancer, characterised by high proliferation rates and cell invasiveness." | ( Astori, G; Belli, R; Bernardi, M; Bozza, A; Catanzaro, D; Celli, P; Chieregato, K; Menarin, M; Merlo, A; Milani, G; Peroni, D; Pozzato, A; Pozzato, G; Raneri, FA; Ruggeri, M; Volpin, L, 2022) |
"Glioblastoma is the most aggressive form of brain tumor, accounting for the highest mortality and morbidity rates." | ( Baig, MH; Cho, JY; Dong, JJ; Hatiboglu, MA; Imran, MA; Khan, I; Khan, MI; Mahfooz, S, 2022) |
" Glioblastoma is the most aggressive and diffusely infiltrative primary brain tumor." | ( Ansari, A; Prajapati, HP, 2023) |
"Glioblastoma is the most common malignant brain cancer with dismal survival and prognosis." | ( Chen, CC; Chen, Y; Grigore, FN; Jin, J; Lan, Q; Li, M; Li, S; Ma, J; Wang, J; Wang, Q; Wu, G; Xu, H; Zhu, H, 2022) |
"Glioblastoma is a fatal brain tumor with a bleak prognosis." | ( Sowers, LC; Sowers, ML, 2022) |
"(1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central nervous system." | ( Celis-López, MÁ; Cid-Sánchez, DR; Contreras-Palafox, GA; Flores-Vázquez, JG; Gutiérrez-Aceves, GA; Heredia-Gutiérrez, JC; Hernández-Sánchez, LC; Macías-González, MDS; Moreno-Jiménez, S; Moscardini-Martelli, J; Olmos-Guzmán, A; Ortiz-Arce, CS; Pérez, SR; Rodríguez-Camacho, A; Suárez-Campos, JJE; Torres-Ríos, JA, 2022) |
"Glioblastoma is the most frequent and lethal primary central nervous system tumor in adults, accounting for around 15% of intracranial neoplasms and 40-50% of all primary malignant brain tumors, with an annual incidence of 3-6 cases per 100,000 population." | ( Chang, PC; Chen, HY; Feng, SW; Huang, SM; Hueng, DY; Li, YF, 2022) |
"Glioblastoma is the most aggressive and lethal brain tumor in adults with highly invasive properties." | ( Chabang, N; Kwanthongdee, J; Munyoo, B; Saengsawang, W; Sunrat, C; Tuchinda, P; Uppakara, K, 2022) |
"Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis." | ( Ge, FH; Hao, RR; Li, WX; Shen, JL; Wang, XL; Xu, AB; Xu, P; Xu, Z, 2022) |
"Glioblastoma is rather recalcitrant to existing therapies and effective interventions are needed." | ( Ding, B; Ding, X; Gao, S; He, M; Heger, M; Jiao, X; Xu, N; Yu, Y; Zhang, J; Zhang, M; Zhang, S, 2022) |
"Glioblastoma is the most prevalent and malignant brain tumor identified in adults." | ( Chagas, RCR; Gonçalves, AS; Melo, ESA; Netto, JB; Oliveira, AGS; Reis, RM; Ribeiro, RIMA; Santiago, LR; Santos, DM; Santos, HB; Sousa, LR; Thomé, RG, 2022) |
"Glioblastoma is the most common and aggressive primary brain tumor, characterized by its high chemoresistance and the presence of a cell subpopulation that persists under hypoxic niches, called glioblastoma stem-like cells (GSCs)." | ( Alarcón, S; Delgado, J; Erices, JI; Fernández-Gajardo, R; Melo, R; Niechi, I; Quezada Monrás, C; Rocha, JD; Salazar-Onfray, F; San Martín, R; Uribe, D, 2022) |
"Glioblastoma is one of the most common intracranial malignant tumors with an unfavorable prognosis, and iron metabolism as well as ferroptosis are implicated in the pathogenesis of glioblastoma." | ( Chen, B; Ge, F; Hao, K; Hao, R; Jiang, W; Li, K; Shen, J; Wang, Z; Xu, A; Yang, W; Zheng, Y, 2022) |
"Glioblastoma is a malignant primary brain tumor that affects approximately 250,000 new patients per year worldwide." | ( Aquilanti, E; Wen, PY, 2022) |
"Glioblastomas are tumors that present a high mortality rate." | ( Andrade, CMB; Branco, CLB; Costa, SA; Cruz, L; da Conceição, AGB; da Silva, KP; Ferrarini, SR; Pires, J; Reis, ÉM; Sinhorin, AP, 2022) |
"Glioblastoma is the most common brain tumor with dismal outcomes in adults." | ( Amano, T; Fujiwara, M; Hirose, H; Matsuo, S; Miyamatsu, Y; Nakamizo, A; Shimamura, T; Yoshimoto, K, 2022) |
"Glioblastoma is a prevalent malignant brain tumor and despite clinical intervention, tumor recurrence is frequent and usually fatal." | ( Carter, CL; Harris, BT; Liapis, E; O'Neill, KC; Perlin, DS, 2022) |
"Glioblastoma is the most common brain tumor." | ( Balkanov, AS; Belyaev, AY; Glazkov, AA; Kobyakov, GL; Rozanov, ID; Shmakov, PN; Strunina, YV; Telysheva, EN; Usachev, DY, 2022) |
"Glioblastoma is the most common brain tumor." | ( Balkanov, AS; Belyaev, AY; Glazkov, AA; Kobyakov, GL; Rozanov, ID; Shmakov, PN; Strunina, YV; Telysheva, EN; Usachev, DY, 2022) |
"Glioblastoma is the most common malignancy of central nervous system, and its prognosis remains very poor mainly due to chemotherapeutic resistance." | ( Chen, XZ; Xu, HB; Xue, F; Yu, ZL, 2023) |
"Treating glioblastoma is difficult due to complicating factors, and novel therapeutic strategies are required to overcome resistance." | ( Cao, J; Fu, Z; Gu, Y; Li, Y; Lin, P; Yan, H, 2022) |
"Glioblastoma is the most common and most aggressive type of primary brain tumor." | ( Bu, XY; Cheng, X; Kong, LF; Luo, JC; Qu, MQ; Wang, YW; Yan, ZY; Yang, DY; Zhao, YW, 2023) |
"Glioblastoma is the most lethal primary brain cancer." | ( Abram, S; Aiken, RD; Ansstas, G; Ashkan, K; Avigan, DE; Baskin, DS; Battiste, JD; Bosch, ML; Bota, DA; Boynton, AL; Brem, S; Brenner, AJ; Campian, JL; Chaudhary, R; Cobbs, CS; D'Andre, S; Dunbar, EM; Elinzano, H; Etame, AB; Ewend, MG; Fink, KL; Geoffroy, FJ; Giglio, P; Gligich, O; Goldlust, SA; Grewal, J; Heth, JA; Iwamoto, FM; Kesari, S; Khagi, S; Kim, L; Krex, D; Lacroix, M; Lee, IY; Liau, LM; Lillehei, K; Lindhorst, SM; Loudon, WG; Lovick, DS; Lutzky, J; Martinez, NL; Mathieu, D; May, SA; Meisel, HJ; Mikkelsen, T; Moshel, YA; Mulholland, PJ; Nadji-Ohl, M; Nam, JY; New, PZ; Peak, S; Pearlman, ML; Petrecca, K; Piccioni, DE; Pillainayagam, CP; Pluard, TJ; Portnow, J; Prins, RM; Salacz, ME; Sanchin, L; Schulder, M; Sloan, A; Taylor, LP; Thompson, RC; Toms, SA; Tran, DD; Trusheim, JE; Tse, V; Villano, JL; Wagner, SA; Walbert, T; Walter, KA; Wu, JK, 2023) |
"Glioblastoma is the most lethal primary brain cancer." | ( Abram, S; Aiken, RD; Ansstas, G; Ashkan, K; Avigan, DE; Baskin, DS; Battiste, JD; Bosch, ML; Bota, DA; Boynton, AL; Brem, S; Brenner, AJ; Campian, JL; Chaudhary, R; Cobbs, CS; D'Andre, S; Dunbar, EM; Elinzano, H; Etame, AB; Ewend, MG; Fink, KL; Geoffroy, FJ; Giglio, P; Gligich, O; Goldlust, SA; Grewal, J; Heth, JA; Iwamoto, FM; Kesari, S; Khagi, S; Kim, L; Krex, D; Lacroix, M; Lee, IY; Liau, LM; Lillehei, K; Lindhorst, SM; Loudon, WG; Lovick, DS; Lutzky, J; Martinez, NL; Mathieu, D; May, SA; Meisel, HJ; Mikkelsen, T; Moshel, YA; Mulholland, PJ; Nadji-Ohl, M; Nam, JY; New, PZ; Peak, S; Pearlman, ML; Petrecca, K; Piccioni, DE; Pillainayagam, CP; Pluard, TJ; Portnow, J; Prins, RM; Salacz, ME; Sanchin, L; Schulder, M; Sloan, A; Taylor, LP; Thompson, RC; Toms, SA; Tran, DD; Trusheim, JE; Tse, V; Villano, JL; Wagner, SA; Walbert, T; Walter, KA; Wu, JK, 2023) |
"Glioblastoma is the most lethal primary brain cancer." | ( Abram, S; Aiken, RD; Ansstas, G; Ashkan, K; Avigan, DE; Baskin, DS; Battiste, JD; Bosch, ML; Bota, DA; Boynton, AL; Brem, S; Brenner, AJ; Campian, JL; Chaudhary, R; Cobbs, CS; D'Andre, S; Dunbar, EM; Elinzano, H; Etame, AB; Ewend, MG; Fink, KL; Geoffroy, FJ; Giglio, P; Gligich, O; Goldlust, SA; Grewal, J; Heth, JA; Iwamoto, FM; Kesari, S; Khagi, S; Kim, L; Krex, D; Lacroix, M; Lee, IY; Liau, LM; Lillehei, K; Lindhorst, SM; Loudon, WG; Lovick, DS; Lutzky, J; Martinez, NL; Mathieu, D; May, SA; Meisel, HJ; Mikkelsen, T; Moshel, YA; Mulholland, PJ; Nadji-Ohl, M; Nam, JY; New, PZ; Peak, S; Pearlman, ML; Petrecca, K; Piccioni, DE; Pillainayagam, CP; Pluard, TJ; Portnow, J; Prins, RM; Salacz, ME; Sanchin, L; Schulder, M; Sloan, A; Taylor, LP; Thompson, RC; Toms, SA; Tran, DD; Trusheim, JE; Tse, V; Villano, JL; Wagner, SA; Walbert, T; Walter, KA; Wu, JK, 2023) |
"Glioblastoma is the most lethal intracranial malignant tumor, for which the five-year overall survival rate is approximately 5%." | ( Ahmad, N; Chen, G; Fu, P; Jiang, X; Li, J; Liu, G; Liu, J; Shi, G; Song, X; Sun, M; Wang, J; Yang, F; Yu, H; Zhang, R; Zhang, Y; Zhou, Y; Zhuang, J, 2023) |
"Glioblastoma is the most lethal intracranial malignant tumor, for which the five-year overall survival rate is approximately 5%." | ( Ahmad, N; Chen, G; Fu, P; Jiang, X; Li, J; Liu, G; Liu, J; Shi, G; Song, X; Sun, M; Wang, J; Yang, F; Yu, H; Zhang, R; Zhang, Y; Zhou, Y; Zhuang, J, 2023) |
"Glioblastoma is the most lethal intracranial malignant tumor, for which the five-year overall survival rate is approximately 5%." | ( Ahmad, N; Chen, G; Fu, P; Jiang, X; Li, J; Liu, G; Liu, J; Shi, G; Song, X; Sun, M; Wang, J; Yang, F; Yu, H; Zhang, R; Zhang, Y; Zhou, Y; Zhuang, J, 2023) |
"Glioblastoma is the most common primary malignant tumor of the central nervous system." | ( Ahmadi-Zeidabadi, M; Amirinejad, M; Jomehzadeh, A; Khoei, S; Kordestani, Z; Larizadeh, MH; Yahyapour, R, 2023) |
"Glioblastoma is the most common primary malignant tumor of the central nervous system." | ( Ahmadi-Zeidabadi, M; Amirinejad, M; Jomehzadeh, A; Khoei, S; Kordestani, Z; Larizadeh, MH; Yahyapour, R, 2023) |
"Glioblastoma is the most common and fatal primary glioma and has a severe prognosis." | ( Cheon, GJ; Jang, HJ; Kang, KW; Lee, YS; Park, CR; Song, MG; Youn, H, 2023) |
"Glioblastoma is the most common malignant tumor of the central nervous system, which originates from glial cells and corresponding precursors." | ( Cheng, P; Han, Q; Ma, H; Yang, H; Zhao, M; Zhao, Y, 2022) |
"Glioblastoma is among the most lethal cancers, with no known cure." | ( Bhatt, H; Brown, JMC; Gray, WP; Ormonde, C; Sharouf, F; Siebzehnrubl, FA; Spencer, R; Zaben, M, 2023) |
"Brain tumor glioblastoma is one of the worst types of cancer." | ( Amerhanova, SK; Antipin, IS; Bakhtiozina, LR; Kadirov, MK; Lyubina, AP; Mansurova, EE; Nizameev, IR; Semenov, VE; Shulaeva, MM; Voloshina, AD; Ziganshina, AY, 2023) |
"Glioblastoma is characterized by extensive vascularization and is highly resistant to current therapy." | ( Xu, T; Zhang, Q; Zhao, J, 2023) |
"Glioblastoma is the most common primary cranial malignancy, and chemotherapy remains an important tool for its treatment." | ( Cai, HR; Cui, HJ; Sun, W; Tang, WH; Yang, H; Zhang, ZN; Zhao, EH, 2023) |
"Glioblastoma is a heterogeneous tumor for which effective treatment options are limited and often insufficient." | ( Beechem, JM; Cimino, PJ; Danaher, P; Glod, J; Hurth, K; Kim, Y; McEachron, TA; Warren, S; Zada, G, 2023) |
"Glioblastomas are highly malignant brain tumors that derive from brain-tumor-initiating cells (BTICs) and can be subdivided into several molecular subtypes." | ( Ammer, LM; Dettmer, K; Hau, P; Heckscher, S; Jachnik, B; Leidgens, V; Moeckel, S; Oefner, PJ; Proescholdt, M; Rauer, L; Riemenschneider, MJ; Seliger, C; Vollmann-Zwerenz, A; Wüster, AL, 2023) |
"Glioblastoma is one of the most malignant and lethal forms of primary brain tumors in adults." | ( Alexiou, GA; Galani, V; Giannakopoulou, M; Kyritsis, AP; Lazari, D; Papagrigoriou, T; Tsekeris, P; Tsiftsoglou, OS; Tzima, E; Zikou, A; Zoi, V, 2023) |
"Glioblastoma is one of the most devastating and incurable cancers due to its aggressive behaviour and lack of available therapies, being its overall-survival from diagnosis ∼14-months." | ( Blanco-Acevedo, C; Castaño, JP; Doval-Rosa, C; Fuentes-Fayos, AC; G-García, ME; Gahete, MD; Jiménez-Vacas, JM; López, M; Luque, RM; Martín-Colom, J; Montero-Hidalgo, AJ; Ortega-Salas, RM; Peralbo-Santaella, E; Pérez-Gómez, JM; Sánchez-Sánchez, R; Solivera, J; Tena-Sempere, M; Toledano-Delgado, Á; Torres, E, 2023) |
"Glioblastoma is a primary intracranial tumour with extremely high disability and fatality rates among adults." | ( Gao, M; Jiang, H; Liu, X; Wang, X; Ye, J; Zhang, D; Zhang, H; Zhao, S, 2023) |
"Glioblastoma is the most common malignant brain tumor in adults." | ( Birkl-Toeglhofer, AM; Brawanski, KR; Freyschlag, CF; Haybaeck, J; Hoeftberger, R; Manzl, C; Sprung, S; Ströbel, T; Thomé, C, 2023) |
"Glioblastoma is one of the most common and invasive types of primary brain malignancies in adults, accounting for 45." | ( Baghbanzadeh, A; Baradaran, B; Barpour, N; Doustvandi, MA; Javadrashid, D; Mohammadpour, ZJ; Mohammadzadeh, R, 2023) |
"Glioblastomas are incurable tumors often associated with epileptic seizures." | ( Venkataramani, V, 2023) |
"Glioblastoma is a refractory malignant tumor that requires novel therapeutic strategies for effective treatment." | ( Ando, S; Ii, H; Kojima, N; Moyama, C; Nakata, S; Nambu, H; Ohta, K, 2023) |
"Glioblastoma is a malignant brain tumor with poor prognosis." | ( Cheng, Q; Dai, Z; Liang, X; Liu, Z; Luo, P; Wang, Z; Wen, Z; Zhang, H; Zhang, J; Zhang, M; Zhang, X, 2023) |
"Glioblastoma is a highly malignant and invasive brain tumor, and there is an urgent need to establish a treatment option that prevents its growth and metastasis." | ( Nakao, S; Ohmori, S; Okamoto, K; Shimizu, T; Tsuchiya, N, 2023) |
"Glioblastoma is the most aggressive primary brain tumor with an unmet need for more effective therapies." | ( Amit, I; Becher, B; Bühler, M; De Luca, R; Di Nitto, C; Hemmerle, T; Katzenelenbogen, Y; Kirschenbaum, D; Look, T; Neri, D; Puca, E; Ravazza, D; Rindlisbacher, L; Roth, P; Stucchi, R; Weiner, A; Weiss, T; Weller, M, 2023) |
"Glioblastomas are highly aggressive and deadly brain tumours, with a median survival time of 14-18 months post-diagnosis." | ( Drill, M; Drummond, KJ; Galea, E; Hunn, M; Jayakrishnan, PC; Kan, LK; Monif, M; O'Brien, TJ; Sanfilippo, PG; Sequeira, RP; Todaro, M; Williams, DA, 2023) |
"Glioblastoma is associated with low median survival time irrespective of maximal treatment." | ( Farzaneh, F; Jangholi, E; Kankam, SB; Khoshnevisan, A; Shafizadeh, M; Shafizadeh, Y, 2023) |
"Glioblastoma is the most common and lethal brain tumor in adults." | ( Iturrioz-Rodríguez, N; Matheu, A; Sampron, N, 2023) |
"Glioblastoma is associated with especially poor outcome in the elderly." | ( Harter, PN; Herms, J; Katzendobler, S; Niedermeyer, S; Niyazi, M; Stoecklein, VM; Thon, N; Tonn, JC; Trumm, C; Weller, J, 2023) |
"Glioblastoma is the most aggressive form of brain tumor originating from glial cells with a maximum life expectancy of 14." | ( Afzal, M; Castresana, JS; Hasan, H; Shahi, MH, 2023) |
"Glioblastoma is the most aggressive and fatal form of brain cancer." | ( Castresana, JS; Denizler-Ebiri, FN; Güven, M; Taşpınar, F; Taşpınar, M, 2023) |
"Glioblastoma is the most common and deadly primary brain tumor in adults." | ( Craig, M; Fiset, B; Jenner, AL; Karimi, E; Quail, DF; Surendran, A; Walsh, LA, 2023) |
"Glioblastomas are aggressive and usually incurable high-grade gliomas without adequate treatment." | ( Grujicic, D; Ilic, R; Isakovic, A; Karapandza, K; Martinovic, T; Raicevic, S; Stanojevic, Z; Tasic, J; Tomonjic, N; Vidicevic-Novakovic, S; Zekovic, J, 2023) |
"Glioblastoma is a cranial malignant tumor with a high recurrence rate after surgery and a poor response to chemoradiotherapy." | ( Liang, X; Lin, H; Sheng, X; Zhou, X, 2023) |
"Glioblastoma is one of the most common malignant brain tumors." | ( Chen, J; Cui, G; Gao, Z; Wang, X; You, YP; Yuan, R; Zhang, W, 2023) |
"Glioblastomas are highly aggressive brain tumors for which therapeutic options are very limited." | ( Carson, SC; Colley, SB; Ingraham, CH; Jursic, BS; Lassak, A; Peruzzi, F; Rak, M; Reiss, K; Stalinska, J, 2023) |
"Glioblastoma is the most frequent and practically incurable neoplasm of the central nervous system; thus, new treatment modalities have been investigated to find a solution more effective than the currently applied standards based on temozolomide." | ( Głowacka, P; Jaskólski, DJ; Pieczonka, AM; Pudlarz, A; Rachwalski, M; Świderska, E; Szemraj, J; Szymańska, J; Witusik-Perkowska, M; Zakrzewska, M, 2023) |
"GBM (Glioblastoma) is the most lethal CNS (Central nervous system) tumor in adults, which inevitably develops resistance to standard treatments leading to recurrence and mortality." | ( Becker, AP; Becker, V; Bell, EH; Chakravarti, A; Cui, T; Fleming, JL; Grosu, AL; Han, C; Haque, SJ; Johnson, B; Kumar, A; Manring, HR; McElroy, J; Meng, X; Robe, PA; Schrock, MS; Sebastian, E; Showalter, CA; Singh, K; Summers, MK; Tong, ZY; Venere, M, 2023) |
"Glioblastoma is the most common aggressive primary central nervous system cancer in adults characterised by uniformly poor survival." | ( Adda, L; Back, M; Bailey, DL; Barnes, EH; Coffey, R; De Abreu Lourenco, R; Ebert, M; Fitt, G; Foroudi, F; Francis, RJ; Gan, HK; Hicks, RJ; Khasraw, M; Koh, ES; Lasocki, A; Lau, E; Lee, ST; Leonard, R; Moffat, BA; Moore, A; Nowak, AK; Roach, P; Rosenthal, M; Scott, AM; Senko, C; Thomas, PA; Verhaak, R; Walsh, KM, 2023) |
"Glioblastoma is a type of intracranial malignancy." | ( Maeoka, R; Matsuda, R; Morimoto, T; Nakagawa, I; Nakase, H; Nakazawa, T; Nishimura, F; Ouji, Y; Park, YS; Yamada, S; Yokoyama, S; Yoshikawa, M, 2023) |
"Glioblastoma is one of the malignant tumors with poor prognosis and no effective treatment is available at present." | ( Chen, J; Shi, SS; Zhang, GL; Zhang, Q; Zheng, SX; Zhuang, BB, 2023) |
"Glioblastoma is a severe brain tumor that requires aggressive treatment involving surgery, radiotherapy, and chemotherapy, offering a survival rate of only 15 months." | ( Bernardes Ferro, M; da Rosa, RG; da Silva, LF; de Oliveira, JVR; de Souza, BM; Henn, JG; Lopes Alves, GA; Morás, AM; Moura, DJ; Nugent, M; Pires Peña, F; Rapack Jacinto Silva, V; Silva Pinheiro, AC; Silveira Aguirre, TA; Steffens Reinhardt, L, 2023) |
"Glioblastoma is the most common brain tumor, with high recurrence and low survival rates." | ( Chen, D; Chen, X; Feng, L; Han, F; Horimoto, K; Kawasaki, A; Kiboku, T; Li, Y; Sheng, G; Sun, M; Tang, Y; Wu, Z; Yao, K; Zhang, R; Zhang, Y, 2023) |
"Glioblastoma is a severe brain tumor characterized by an extremely poor survival rate of patients." | ( Barilà, D; Borsellino, G; Cirotti, C; Contadini, C; De Bardi, M; Di Girolamo, C; Helmer-Citterich, M; Pepe, G; Taddei, I, 2024) |