aza-steroid

An aza-steroid is a steroid where in the carbon skeleton a carbon atom is replaced by nitrogen.

ChEBI ID: 35726

Members (3)

Member	Definition	Role
dutasteride	An aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland.	dutasteride
finasteride	An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.	finasteride
u 73122	An aza-steroid that is 3-O-methyl-17beta-estradiol in which the 17beta-hydroxy group is replaced by a 6-(maleimid-1-yl)hexylamino group. An inibitor of phospholipase C.	U-73122