An alkanethiol is a compound in which a sulfanyl group, -SH, is attached to an alkyl group.
ChEBI ID: 47908
| Member | Definition | Role |
|---|---|---|
| 1,6-hexanedithiol | 1,6-Hexanedithiol | |
| 1,8-octanedithiol | 1,8-Octanedithiol | |
| 3-mercapto-2-methylpentan-1-ol | 3-Mercapto-2-methylpentanol | |
| 3-mercaptohexanol | An alkanethiol that is hexane substituted at positions 1 and 3 by hydroxy and sulfanyl groups respectively. | 3-mercaptohexanol |
| 3-mercaptohexyl acetate | An acetate ester obtained by formal O-acetylation of 3-mercaptohexanol. | 3-mercaptohexyl acetate |
| 3-methyl-2-butene-1-thiol | 3-Methyl-2-butene-1-thiol | |
| 4-methyl-4-sulfanylpentan-2-one | An alkylthiol that is 4-methylpentan-2-one substituted at position 4 by a mercapto group. | 4-mercapto-4-methylpentan-2-one |
| captopril | A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug. | captopril |
| ethanethiol | An alkanethiol that is ethane substituted by a thiol group at position 1. It is added to odorless gaseous products such as liquefied petroleum gas (LPG) to provide a garlic scent which helps warn of gas leaks. | ethanethiol |
| mercaptoethanol | mercaptoethanol | |
| methylmercaptan | methanethiol | |
| n-butyl mercaptan | butanethiol | |
| n-octanethiol | An alkanethiol that is octane substituted by a thiol group at position 1. | octane-1-thiol |
| propanethiol | An alkanethiol that is propane substituted by a thiol group at position 1. | propane-1-thiol |
| wr 1065 | An alkanethiol that is the N-3-aminopropyl derivative of cysteamine. Used as the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy. | WR-1065 |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8,376 (50.66) | 18.7374 |
| 1990's | 4,253 (25.72) | 18.2507 |
| 2000's | 2,240 (13.55) | 29.6817 |
| 2010's | 1,362 (8.24) | 24.3611 |
| 2020's | 304 (1.84) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,569 (9.00%) | 5.53% |
| Reviews | 632 (3.62%) | 6.00% |
| Case Studies | 924 (5.30%) | 4.05% |
| Observational | 5 (0.03%) | 0.25% |
| Other | 14,310 (82.05%) | 84.16% |