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ergoline alkaloid

One of a class of naturally occurring alkaloids with a structure based on that of ergoline.

ChEBI ID: 60529

Members (11)

MemberDefinitionRole
ergolineAn indole alkaloid whose structural skeleton is found in many naturally occurring and synthetic ergolines which are known to bind to neurotransmitter receptors, such as dopamine, noradrenaline and serotonin receptors and function as unselective agonists or antagonists at these receptors.ergoline
lysergamideAn ergoline alkaloid comprising ergoline lacking hydrogens at positions 9 and 10 and also having a methyl group attached to the piperidine nitrogen.lysergamide
lysergic acid diethylamideAn ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine.lysergic acid diethylamide
lysergolAn alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at C-8.lysergol
metergolineAn ergoline alkaloid that is the N-benzyloxycarbonyl derivative of lysergamine. A 5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7.metergoline
methergineN-(1-hydroxybutan-2-yl)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
methylergonovine(6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
methylergonovine maleateMethylergonovine Maleate
methysergide(6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide
methysergide maleateMethysergide maleate
sansertN-(1-hydroxybutan-2-yl)-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide

Research

Studies (12,157)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19908,070 (66.38)18.7374
1990's1,931 (15.88)18.2507
2000's1,008 (8.29)29.6817
2010's846 (6.96)24.3611
2020's302 (2.48)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials704 (5.14%)5.53%
Reviews766 (5.60%)6.00%
Case Studies706 (5.16%)4.05%
Observational13 (0.09%)0.25%
Other11,498 (84.01%)84.16%