Any compound that has anti-inflammatory effects.
| Member | Definition | Class |
|---|
| (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside | A stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. | (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside |
| 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose | A galloyl-beta-D-glucose compound having five galloyl groups in the 1-, 2-, 3-, 4- and 6-positions. | 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose |
| 1,3,7,9-tetramethyluric acid | An oxopurine that is uric acid in which the hydrogens at positions 1,3,7 and 9 are replaced by methyl groups. It is a purine alkaloid that is found in Chinese tea known as kucha (Camellia assamica var. kucha) and exhibits anti-inflammatory and analgesic properties. | 1,3,7,9-tetramethyluric acid |
| 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine | A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and the hydrogen at position 2 on the adenine is replaced by a 4-(2-carboxyethyl)phenethylamino group. | CGS-21680 |
| 2-hydroxyacetanilide | A member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. | 2-acetamidophenol; 2'-Hydroxyacetanilide |
| 2-methyl-1,4-hydroquinone | A member of the class of hydroquinones that is hydroquinone in which one of the benzene hydrogens has been replaced by a methyl group. | toluquinol |
| 2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9h-xanthen-9-one | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 2, 3, 6 and 8, an isoprenyl group at position 1 and a 2-methylbut-3-en-2-yl group at position 5. It is isolated from the root barks of Cudrania tricuspidata and exhibits cytotoxicity towards human cancer cell lines. | cudratricusxanthone A |
| 2'-hydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 2'. | 2'-hydroxychalcone |
| 2'-hydroxyformononetin | A member of the class of 4'-methoxyisoflavones that is formononetin with a hydroxy group at the 2'position. | 2'-hydroxyformononetin |
| 23-hydroxytormentic acid | A pentacyclic triterpenoid that is asiatic acid substituted by a hydroxy group at position 19. It has been isolated from the leaves of Rosa laevigata. | 19alpha-hydroxyasiatic acid |
| 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease. | TDZD-8 |
| 4-hydroxycordoin | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at position 4 and 2' and a (3-methylbut-2-en-1-yl)oxy group at position 4'. It has been isolated from Lonchocarpus neuroscapha. | 4-hydroxycordoin |
| 4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol | A terpineol that is 1-menthene carrying a hydroxy substituent at position 4. | 4-terpineol |
| 4-methylesculetin | A hydroxycoumarin that is 4-methylcuomarin which is substituted by hydroxy groups at positions 3 and 4. A hyaluronan synthesis inhibitor. It has also been used as a fluorescent sensor to monitor the consumption of a boronic acid in Suzuki coupling reactions; fluorescence is readily detectable by the naked eye using a standard 365 nm UV lamp. | 6,7-dihydroxy-4-methylcoumarin |
| 4'-hydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4'. | 4'-hydroxychalcone |
| 4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a methyl group at position 4 and oxo groups at positions 3, 7 and 11 (the 4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic and anti-inflammatory activity. | zhankuic acid A |
| 5,4'-dihydroxy-7,3'-dimethoxyflavone | A dimethoxyflavone that is luteolin in which the hydroxy groups at positions 7 and 3' are replaced by methoxy groups. | velutin |
| 5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4h-1-benzopyran-4-one | A member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. | rohitukine |
| 5s,12r,18r-trihydroxy-6z,8e,10e,14z,16e-eicosapentaenoic acid | A resolvin that is (6Z,8E,10E,14Z,16E)-icosa-6,8,10,14,16-pentaenoic acid which is substituted at positions 5, 12 and 18 by hydroxy groups (the 5S,12R,18R stereoisomer). | resolvin E1 |
| 6,7,4'-trihydroxyisoflavone | A hydroxyisoflavone that is daidzein bearing an additional hydroxy substituent at position 6. | 4',6,7-trihydroxyisoflavone |
| 7-deacetylgedunin | A limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica. | 7-deacetylgedunin |
| 7-hydroxydehydroepiandrosterone | An androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7alpha-position. | 7alpha-hydroxydehydroepiandrosterone |
| 9-PAHSA | A FAHFA (fatty acid ester of a hydroxy fatty acid) obtained by formal condensation of the carboxy group of palmitic acid with the hydroxy group of 9-hydroxyoctadecanoic acid (9-hydroxystearic acid). | 9-PAHSA |
| 9,11-linoleic acid | An octadeca-9,11-dienoic acid having 9-trans,11-trans-stereochemistry. | (9E,11E)-octadecadienoic acid |
| absynthin | A dimeric sesquiterpene lactone that is produced by the plant Artemisia absinthium (Wormwood). The bitter tasting constituent of Absinthe. | absinthin |
| abt-737 | A biphenyl that is 4-chloro-1,1'-biphenyl substituted by a (4-{4-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene-1-sulfonyl)carbamoyl]phenyl}piperazin-1-yl)methyl group at position 2'. It is a BH3-mimetic drug which targets the anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins, including BCL-2, BCL-xL, and BCL-w, and induces apoptosis in cancer cells. | ABT-737 |
| acteoside | A glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid. | acteoside |
| ag-490 | A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid with the amino group of benzylamine. | tyrphostin B42 |
| agnuside | A benzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with the primary hydroxy group of aucubin. It is an iridoid glycoside found in several Vitex plants including Vitex agnus-castus. | agnuside |
| alpha-msh | A thirteen amino acid peptide hormone consisting of N-acetyl-L-Ser, L-Tyr, L-Ser, L-Met, L-Glu, L-His, L-Phe, L-Arg, L-Trp, Gly, L-Lys, L-Pro and L-valinamide units joined in sequence by peptide linkages. It is an endogenous melanocortin receptor agonist that exhibits anti-inflammatory activity. | alpha-melanocyte stimulating hormone |
| anacardic acid | A hydroxybenzoic acid that is salicylic acid substituted by a pentadecyl group at position 6. It is a major component of cashew nut shell liquid and exhibits an extensive range of bioactivities. | anacardic acid |
| antofine | An organic heteropentacyclic compound that is (13aR)-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups. It is an alkaloid produced by relatives of the milkweed family and exhibits antiviral, anti-inflammatory, antiadipogenic and antitumorigenic activities. | (-)-antofine |
| antrocamphin a | A methoxybenzene that is 1,2,5-trimethoxy-3-methylbenzene substituted by a 3-methylbut-3-en-1-yn-1-yl group at position 4. It is isolated from Antrodia camphorata and exhibits anti-inflammatory activity. | antrocapmphin A |
| arachidonoylserotonin | An N-acylserotonin obtained by formal condensation of the carboxy group of arachidonic acid with the primary amino group of serotonin. | N-arachidonoylserotonin |
| aromaticin | A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8 and a methylidene group at position 3. Isolated from the aerial parts of Inula hupehensis, it exhibits anti-inflammatory activity. | aromaticin |
| as 605240 | A quinoxaline derivative that is quinoxaline in which the hydrogen at position 6 is replaced by a (2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl group. It is a potent inhibitor of the PI3Kgamma, with an IC50 of 8 nM and inhibits the progression of joint inflammation and damage in both lymphocyte-independent and dependent mouse models of rheumatoid arthritis. | (5Z)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolidine-2,4-dione |
| astilbin | A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage. | astilbin |
| astragaloside IV | A pentacyclic triterpenoid that is cycloastragenol having beta-D-xylopyranosyl and beta-D-glucopyranosyl residues attached at positions O-3 and O-6 respectively. It is isolated from Astragalus membranaceus var mongholicus. | astragaloside IV |
| AZ3451 | A member of the class of benzimidazoles that is 1H-benzimidazole substituted by (1S)-1-cyclohexylethyl, 6-bromo-1,3-benzodioxol-5-yl, and 4-(cyanoanilino)acyl groups at positions 1, 2 and 5, respectively. It is an allosteric modulator of protease-activated receptor 2 (IC50 = 23 nM) and exhibits anti-osteoarthritis properties. | AZ3451 |
| azadiradione | A tetracyclic triterpenoid that is 4,4,8-trimethylandrosta-1,14-diene substituted by oxo groups at positions 3 and 16, an acetoxy group at position 7 and a furan-3-yl group at position 17. Isolated from Azadirachta indica, it exhibits antimycobacterial and anti-inflammatory activities. | azadiradione |
| baicalein | A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. | baicalein |
| baohuoside i | A glycosyloxyflavone that is 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone in which the hydroxy group at position 3 has been converted into its alpha-L-rhamnopyranoside. | icariside II |
| baricitinib | A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a 1-[3-(cyanomethyl)-1-(ethanesulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl group at position 5. It is an FDA approved selective Janus Kinase 1 and 2 (JAK1 and JAK2) inhibitor used for the treatment of rheumatoid arthritis. | baricitinib |
| bay 11-7085 | A sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IkappaB-alpha phosphorylation in cells (IC50 = 10 muM) and prevents the activation of NF-kappaB. | BAY11-7085 |
| bay 60-6583 | A member of the class of cyanopyridines that is 6-amino-3,5-dicyano-4-(4-hydroxyphenyl)-2-sulfanylpyridine in which the hydroxy and sulfanyl hydrogens are replaced by cyclopropylmethyl and carboxamidomethyl groups respectively. | BAY 60-6583 |
| beraprost | An organic heterotricyclic compound that is (3aS,8bS)-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan in which the hydrogens at positions 1R, 2R and 5 are replaced by (3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl, hydroxy and 3-carboxypropyl groups, respectively. It is a prostaglandin receptor agonist which is approved to treat pulmonary arterial hypertension in Asia. | beraprost |
| beraprost sodium | The organic sodium salt of beraprost. It is used in the treatment of chronic arterial occlusive disease and primary pulmonary hypertension in Japan. | beraprost sodium |
| beta-lapachone | A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities. | beta-lapachone |
| betulin | A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents. | betulin |
| betulinic acid | A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. | betulinic acid |
| brazilin | A organic heterotetracyclic compound that is a red pigment obtained from the wood of Caesalpinia echinata (Brazil-wood) or Caesalpinia sappan (sappan-wood). | brazilin |
| bufalin | A 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo. | bufalin |
| butrin | A flavanone glycoside that is butin substituted by two beta-D-glucopyranosyl residues at positions 7 and 3' respectively. | butrin |
| cafestol | An organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). | cafestol |
| caffeic acid phenethyl ester | An alkyl caffeate ester in which 2-phenylethyl is the alkyl component. | phenethyl caffeate |
| camostat | A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients. | camostat |
| camostat mesylate | A methanesulfonate (mesylate) salt prepared from equimolar amounts of camostat and methanesulfonic acid. It is a serine protease inhibitor approved and marketed in Japan in 1985 for the alleviation of acute symptoms associated with chronic pancreatitis. In 1994, it was approved for the treatment of postoperative reflux esophagitis. | camostat mesylate |
| cannabigerol | A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species. | cannabigerol |
| capsiate | A carboxylic ester obtained by formal condensation of the carboxy group of (6E)-8-methylnon-6-enoic acid with the benzylic hydroxy group of vanillyl alcohol. A non-pungent analogue of capsaicin with a similar biological profile. | capsiate |
| castanospermine | A tetrahydroxyindolizidine alkaloid that consists of octahydroindolizine having four hydroxy substituents located at positions 1, 6, 7 and 8 (the 1S,6S,7R,8R,8aR-diastereomer). | castanospermine |
| cauloside D | A triterpenoid saponin with hederagenin as the aglycone part. It has been isolated from the stem bark of Kalopanax pictus. | cauloside D |
| cenicriviroc | A member of the class of benzazocines that is (5Z)-1,2,3,4-tetrahydro-1-benzazocine which is substituted by a 2-methylpropyl, N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl]phenyl}carboxamide and 4-(2-butoxyethoxy)phenyl groups at positions 1, 5 and 8, respectively. It is a potent chemokine 2 and 5 receptor antagonist currently in development for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis (NASH). | cenicriviroc |
| cgp 42112a | A hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist. | CGP-42112A |
| chrysin | A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. | chrysin |
| chrysophanic acid | A trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity. | chrysophanol |
| cleomiscosin a | An organic heterotricyclic compound that is 2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one substituted by 4-hydroxy-3-methoxy phenyl group at position 3, a hydroxymethyl group at position 2 and a methoxy group at position 5 (the 2R,3R stereoisomer). It exhibits anti-inflammatory activity. | cleomiscosin A |
| colchicine | A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions. | (S)-colchicine |
| columbianadin | An alpha,beta-unsaturated carboxylic ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. | columbianadin |
| confertin | A pseudoguaianolide that is decahydroazuleno[6,5-b]furan-2(3H)-one substituted by an oxo group at position 5, methyl groups at positions 4a and 8 and a methylidene group at position 3. It has been isolated from the aerial parts of Inula hupehensis. | confertin |
| coumestrol | A member of the class of coumestans that is coumestan with hydroxy substituents at positions 3 and 9. | coumestrol |
| cryptolepine | An organic heterotetracyclic compound that is 5H-indolo[3,2-b]quinoline in which the hydrogen at position N-5 is replaced by a methyl group. | cryptolepine |
| cubebin | A lignan that consists of tetrahydrofuran-2-ol substituted by two 1,3-benzodioxol-5-ylmethyl groups at positions 3 and 4 respectively (the 2S,3R,4R stereoisomer). It is isolated from the leaves of Piper nigrum and exhibits analgesic, anti-inflammatory, antimicrobial and trypanocidal activities. | (-)-cubebin |
| curcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. | curcumin |
| decane-1,2-diol | A glycol that is decane bearing two hydroxy substituents located at positions 1 and 2. | decane-1,2-diol |
| decanoic acid | A C10, straight-chain saturated fatty acid. | decanoic acid |
| deguelin | A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers. | deguelin |
| dehydrodiconiferyl alcohol | A guaiacyl lignin obtained by cyclodimerisation of coniferol. | dehydrodiconiferyl alcohol |
| delta(9)-tetrahydrocannabinolic acid | A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant. | Delta(9)-tetrahydrocannabinolic acid |
| demethoxycurcumin | A beta-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior. | demethoxycurcumin |
| demethylzeylasteral | A carbopolycyclic compound with formula C29H36O6, originally isolated from Tripterygium wilfordii. | demethylzeylasteral |
| diallyl trisulfide | An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity | diallyl trisulfide |
| dioscin | A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage. | dioscin |
| diosmetin | A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. | diosmetin |
| diosmin | A disaccharide derivative that consists of diosmetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | diosmin |
| dipyrone | A pyrazole that is antiipyrine substituted at C-4 by a methyl(sulfomethyl)amino group, the sodium salt of which, metamizole sodium, was widely used as a powerful analgesic and antipyretic, but withdrawn from many markets from the 1970s due to a risk of causing risk of causing agranulocytosis. | metamizole |
| dipyrone | An organic sodium salt of antipyrine substituted at C-4 by a methyl(sulfonatomethyl)amino group, commonly used as a powerful analgesic and antipyretic. | metamizole sodium |
| ecteinascidin 743 | A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer. | trabectedin |
| epi-maslinic acid | A pentacyclic triterpenoid that is 3alpha-hydroxy epimer of maslinic acid. Isolated from Prunella vulgaris and Isodon japonicus, it exhibits anti-inflammatory activity. | epi-maslinic acid |
| epoxyazadiradione | A limonoid that is azadiradione with an epoxy group across positions 14 and 15. Isolated from Azadirachta indica it exhibits insecticidal activitry against mosquitoes. | epoxyazadiradione |
| ergolide | A sesquiterpene lactone that is decahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8, a methylidene group at position 3 and an acetyloxy group at position 4. It has been isolated from the aerial parts of Inula hupehensis. | ergolide |
| ermanin | A dimethoxyflavone that is kaempferol in which the hydroxy groups at position 3 and 4' have been replaced by methoxy groups. It is a component of bee glue and isolated from several plant species including Tanacetum microphyllum. | 3,4'-dimethylkaempferol |
| ethyl caffeate | An ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. | Caffeic acid ethyl ester; ethyl trans-caffeate |
| ethyl linoleate | A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of linoleic acid with the hydroxy group of ethanol. | ethyl linoleate |
| eupatilin | A trimethoxyflavone that is flavone substituted by hydroxy groups at C-5 and C-7 and methoxy groups at C-6, C-3' and C-4' respectively. Isolated from Citrus reticulata and Salvia tomentosa, it exhibits anti-inflammatory, anti-ulcer and antineoplastic activities. | eupatilin |
| eupatorin | A trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups. | eupatorin |
| eupomatenoid 6 | A member of the class of benzofurans that is 1-benzofuran substituted by a 4-hydroxyphenyl group at position 2, a methyl group at position 3 and a prop-1-en-1-yl group at position 5. It is a lignan derivative isolated from the roots of Krameria lappacea. | rataniaphenol II |
| fangchinoline | A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity. | fangchinoline |
| ferulic acid | A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. | ferulic acid |
| fisetin | A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'. | fisetin |
| flavokawain b | A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy group at positions 2' and methoxy groups at positions 4' and 6'. Isolated from Piper methysticum and Piper rusbyi, it exhibits antileishmanial, anti-inflammatory and antineoplastic activities. | flavokawain B |
| fraxetin | A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. | fraxetin |
| fraxin | A beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo. | fraxin |
| genipin | | Genipin |
| germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
| ginsenoside m1 | A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | ginsenoside C-K |
| ginsenoside re | A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. | ginsenoside Re |
| goralatide | A tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties. | Ac-Ser-Asp-Lys-Pro-OH; goralatide |
| helenalin | A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3aS,4S,4aR,7aR,8R,9aR stereoisomer). | helenalin |
| herbacetin | A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities. | herbacetin |
| hispidulin | A monomethoxyflavone that is scutellarein methylated at position 6. | hispidulin |
| histidyl-proline diketopiperazine | A homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). | cyclo(L-His-L-Pro) |
| hu 308 | A carbobicyclic compound that is bicyclo[3.1.1]hept-2-ene which is substituted by a hydroxymethyl group at position 2, a 2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl group at position 4, and two methyl groups at position 6 (the 1S,4S,5S stereoisomer). A highly selective and effective cannabinoid type-2 agonist and the enantiomer of HU-433. | HU-308 |
| ilomastat | An N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor | ilomastat |
| inuviscolide | A sesquiterpene lactone that is decahydroazuleno[6,5-b]furan-2(3H)-one substituted by a hydroxy group at position 5, a methyl group at position 5 and methylidene groups at positions 3 and 8 (the 3aR,4aR,5R,7aS,9aS stereoisomer). Isolated from the aerial parts of Inula hupehensis, it exhibits anti-inflammatory activity. | inuviscolide |
| isobutrin | A member of the class of chalcones that is trans-chalcone substituted by beta-D-glucopyranosyloxy groups at positions 3 and 4' and hydroxy groups at positions 4 and 2' respectively. | isobutrin |
| isonaringin | A disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | narirutin |
| jaceosidin | A trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties. | jaceosidin |
| jq1 compound | A member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties. | JQ1 |
| jte 013 | A semicarbazide derivative that is semicarbazide in which the amino group at position 2 is replaced by a [1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl]amino group and the amino group adjacent to the carbonyl is replaced by a (2,6-dichloropyridin-4-yl)amino group. It is a potent S1P2 antagonist (IC50 = 17.6 nM). | JTE-013 |
| jte 607 | The dihydrochloride salt of JTE-607. It is a cytokine inhibitor which suppresses the production of proinflammatory cytokines such as interleukin (IL-1beta), IL-6, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor (TNF-alpha). It acts as a pro-drug which is cleaved by carboxylesterase 1 (CES1) to its active free acid form, which then binds to cleavage and polyadenylation specificity factor 3 (CPSF3). | JTE-607 dihydrochloride |
| jwh-133 | A dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. | JWH-133 |
| kaempferol 3-o-rhamnoside | A glycosyloxyflavone that is kaempferol attached to an alpha-L-rhamnosyl residue at position 3 via a glycosidic linkage. | afzelin |
| kahweol | A diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. | kahweol |
| kalopanax saponin b | A triterpenoid saponin with hederagenin as the aglycone part. It has been isolated from the stem bark of Kalopanax pictus. | kalopanaxsaponin B |
| kurarinol | A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2' and 4' , a methoxy group at position 5 and a (2S)-5-hydroxy-5-methyl-2-(prop-1-en-2-yl)hexyl group at position 8 respectively. | kurarinol |
| kuwanon g | A tetrahydroxyflavone isolated from the root barks of Morus alba and has been shown to exhibit anti-inflammatory activity. | kuwanone G |
| lanthionine ketimine | A member of the class of 1,4-thiazines that is 3,6-dihydro-2H-1,4-thiazine substituted by carboxy groups at positions 3 and 5. It is a natural but non-proteogenic amino acid found in human urine and brain. | lanthionine ketimine |
| lespenefril | A glycosyloxyflavone that is kaempferol attached to alpha-L-rhamnopyranosyl residues at positions 3 and 7 respectively via glycosidic linkages. It has been isolated from the aerial parts of Vicia faba and Lotus edulis. | kaempferol 3,7-di-O-alpha-L-rhamnoside |
| leukotriene b5 | A leukotriene composed of (6Z,8E,10E,14Z,17Z)-icosapentaenoic acid carrying (5S)- and (12R)-hydroxy substituents. | leukotriene B5 |
| likviriton | A flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. | liquiritin |
| lisofylline | A 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus. | (R)-lisofylline |
| loganin | An iridoid monoterpenoid with formula C17H26O10 that is isolated from several plant species and exhibits neuroprotective and anti-inflammatory properties. | loganin |
| luteolin | A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. | luteolin |
| madecassoside | A triterpenoid saponin that is a trisaccharide derivative of madecassic acid. Isolated from Centella asiatica, it exhibits anti-inflammatory, antioxidant and antirheumatic activities. | madecassoside |
| mangiferin | A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. | mangiferin |
| maslinic acid | A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. | maslinic acid |
| menatetrenone | A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. | menaquinone-4 |
| meso-zeaxanthin | A carotenol that is beta,beta-carotene carrying two hydroxy substituents at positions 3 and 3' (the 3R,3'S-diastereomer). It is rarely found in diet and is believed to be formed at the macula by metabolic transformations of ingested carotenoids. | meso-zeaxanthin |
| methyl gallate | A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties. | methyl 3,4,5-trihydroxybenzoate |
| methylprednisolone suleptanate | An organic sodium salt that is the monosodium salt of methylprednisolone 21-suleptanic acid ester. It is a prodrug of methylprednisolone developed by Pharmacia Corp for the treatment of asthma. | methylprednisolone suleptanate |
| miltefosine | A phospholipid that is the hexadecyl monoester of phosphocholine. | miltefosine |
| mln 4760 | A L-histidine derivative that is L-histidine in which a hydrogen of the primary amino group is substituted by a (1S)-1-carboxy-3-methylbutyl group and the ring NH group is substituted by a 3,5-dichlorobenzyl group. It is a potent and selective human angiotensin-converting enzyme 2 (ACE2) inhibitor (IC50 = 0.44 nM) which was in clinical development for the treatment of ulcerative colitis. | MLN-4760 |
| monascorubrin | | monascorubrin |
| monotropein | An iridoid monoterpenoid that is 1,4a,7,7a-tetrahydrocyclopenta[c]pyran substituted by a beta-D-glucopyranosyloxy group at position 1, a carboxylic acid group at position 4, and at position 7 by a hydroxy and hydroxymethyl groups respectively (the 1S,4aS,7R,7aS diastereomer). | monotropein |
| morin | A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5. | morin |
| muromonab-cd3 | An extended flavonoid that consists of a pyranochromane skeleton that is 2H,6H-pyrano[3,2-g]chromen-6-one substituted by geminal methyl groups at position 2, a 2,4-dihydroxyphenyl group at position 8, a hydroxy group at position 5 and a prenyl group at position 7. Isolated from Morus alba and Morus species it exhibits anti-inflammatory activity. | cudraflavone B |
| myrcene | A monoterpene that is octa-1,6-diene bearing methylene and methyl substituents at positions 3 and 7 respectively. | beta-myrcene |
| myrsinoic acid b | A member of the class of 1-benzofurans that is 2,3-dihydro-1-benzofuran substituted by a carboxy group at position 5, a 1',5'-dimethyl-1'-hydroxy-4'-hexenyl group at position 2 and a prenyl group at position 7. Isolated from Myrsine seguinii, it exhibits anti-inflammatory activity. | myrsinoic acid B |
| n(1)-methylnicotinamide | A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent. | 1-methylnicotinamide |
| naringenin chalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively. | 2',4,4',6'-tetrahydroxychalcone |
| naringin | A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | naringin |
| niacinamide | A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. | nicotinamide |
| np 031112 | A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. | tideglusib |
| ochnaflavone | A biflavonoid with an ether linkage between the B-rings of the apigenin and luteolin subunits. It has been isolated from several members of the Ochnaceae plant family. | ochnaflavone |
| oleuropein | A secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. | oleuropein |
| oleuropein aglycone | A secoiridoid that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2R,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. | oleuropein aglycone |
| ombuine | A dimethoxyflavone that is quercetin in which the hydroxy groups at positions 7 and 4' are replaced by methoxy groups. Isolated from Cyperus teneriffae, it exhibits anti-inflammatory activity. | ombuin |
| orobol | A member of the class of 7-hydroxyisoflavones which consists of isoflavone substituted by hydroxy groups at positions 5, 7, 3' and 4'. It has been isolated from the mycelia of Cordyceps sinensis. | orobol |
| ospemifene | An organochlorine compound that is a selective estrogen receptor modulator; used for treatment of dyspareunia. | ospemifene |
| oxatomide | A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug. | oxatomide |
| pectolinarin | A disaccharide derivative that consists of pectolinarigenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | pectolinarin |
| pentamidine | A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. | pentamidine |
| ph 797804 | A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine. | PH 797804 |
| physcione | A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources. | physcion |
| picrinine | A natural product with formula C20H22N2O3 that is the member of the akuammiline family of alkaloids, first isolated in 1965 from the leaves of Alstonia scholaris. | picrinine |
| pinellic acid | A trihydroxyoctadecenoic acid with hydroxy groups at positions C-9, -12, and 13, and an E (cis) double bond at position 10. | pinellic acid |
| piperlactam s | An organic heterotetracyclic compound that is dibenzo[cd,f]indol-4(5H)-one carrying two methoxy substituents at positions 1 and 5 as well as a hydroxy substituent at position 2. | piperlactam S |
| pj-34 | A member of the class of phenanthridines that is 5,6-dihydrophenanthridine substituted at positions 2 and 6 by (N,N-dimethylglycyl)amino and oxo groups, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 110 nM and 86 nM, respectively) and exhibits anti-cancer, cardioprotective and neuroprotective properties. | PJ34 |
| pqq cofactor | A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions. | pyrroloquinoline quinone |
| praliciguat | A member of the class of pyrazoles that is 5-fluoro-2-(1H-pyrazol-3-yl)pyrimidine which is substituted by a 2-fluorobenzyl group at position 1, 1,2-oxazol-3-yl group at position 5, and by a [3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]nitrilo group at position 4. It is a soluble guanylate cyclase stimulator under clinical development for the treatment of heart failure with preserved ejection fraction. | praliciguat |
| prednisolone phosphate | A synthetic glucocorticoid resulting from the formal condensation of the 21-hydroxy group of prednisolone with one of the hydroxy groups of phosphoric acid. It is a prodrug for prednisolone that is activated in vivo by phosphatases. | prednisolone phosphate |
| procyanidin b1 | A proanthocyanidin consisting of (-)-epicatechin and (+)-catechin units joined by a bond between positions 4 and 8' respectively in a beta-configuration.. Procyanidin B1 can be found in Cinnamomum verum (Ceylon cinnamon, in the rind, bark or cortex), in Uncaria guianensis (cat's claw, in the root), and in Vitis vinifera (common grape vine, in the leaf) or in peach. | procyanidin B1 |
| procyanidin b3 | A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarpo Macho. | procyanidin B3 |
| procyanidin C1 | A proanthocyanidin consisting of three (-)-epicatechin units joined by two successive (4beta->8)-linkages. | procyanidin C1 |
| protectin d1 | A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17S-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1 | protectin D1 |
| prunetin | A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group. | prunetin |
| pterostilbene | A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'. | pterostilbene |
| pulsatilla saponin a | A triterpenoid saponin that is hederagenin attached to a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage. It has been isolated from the stem bark of Kalopanax pictus. | kalopanaxsaponin A |
| quillaic acid | A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 3 and 16, an oxo group at position 23 and a carboxy group at position 28 (the 3beta,16alpha stereoisomer). | quillaic acid |
| resolvin d1 | A resolvin that is docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid which is substituted by hydroxy groups at the 7, 8, and 17 positions (the 7S,8R,17S-stereoisomer). | resolvin D1 |
| resolvin d2 | A member of the class of resolvins that is (4Z,8E,10Z,12E,14E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 7, 16 and 17 (the 7S,16R,17S-stereoisomer). | resolvin D2 |
| resolvin d3 | A member of the class of resolvins that is (5Z,7E,9E,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 11 and 17 (the 4S,11R,17S-stereoisomer). | resolvin D3 |
| resolvin D4 | A member of the class of resolvins that is (6E,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 5 and 17 (the 4S,5R,17S-stereoisomer). | resolvin D4 |
| resolvin e2 | A member of the class of resolvins that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid carrying two hydroxy substituents at positions 5 and 18 (the 5S,18R stereoisomer). | resolvin E2 |
| rhamnetin | A monomethoxyflavone that is quercetin methylated at position 7. | rhamnetin |
| rhapontin | A rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. | trans-rhaponticin |
| riboflavin | D-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. | riboflavin |
| rosuvastatin | A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer). | rosuvastatin |
| rosuvastatin calcium | An organic calcium salt that is the hemicalcium salt of rosuvastatin. | rosuvastatin calcium |
| rp 73401 | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine. | piclamilast |
| rubimaillin | A benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. | rubimaillin |
| salvianolic acid B | A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza | salvianolic acid B |
| salvin | An abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20. It is isolated from rosemary (Rosmarinus officinalis) and common sage (Salvia officinalis) and exhibits anti-angiogenic, antineoplastic, antioxidant and anti-HIV activity. | carnosic acid |
| sappanchalcone | A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy groups at positions 3, 4 and 4' and a methoxy group at position 2'. Isolated from Caesalpinia sappan, it exhibits neuroprotective and cytoprotective activity. | sappanchalcone |
| savinin | A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 1,3-benzodioxol-5-ylmethylidene group at position 3 and a 1,3-benzodioxol-5-ylmethyl group at position 4 (the 3E,4R-isomer). It exhibits antiviral activity against SARS-CoV-2. | savinin |
| sb 220025 | Am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively. | SB220025 |
| scalaradial | A scalarane sesterterpenoid with formula C27H40O4. It is a natural product found in the marine sponges Spongia officinalis and Cacospongia mollior, and exhibits anti-inflammatory activity. | scalaradial |
| schizandrin b | An organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis. | (+)-schisandrin B; Deoxygomisin A |
| scoparone | A member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. | scoparone |
| sigmoidin a | A tetrahydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' and prenyl groups at positions 2' and 5'. Isolated from Erythrina sigmoidea, it exhibits anti-inflammatory and antioxidant activities. | sigmoidin A |
| sirtinol | A benzamide obtained by formal condensation of the carboxy group of 2-{[(2-hydroxy-1-naphthyl)methylene]amino}benzoic acid with the amino group of 1-phenylethylamine. | sirtinol |
| stevioside | A diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America. | stevioside |
| swertisin | A flavone C-glycoside that is 7-O-methylapigenin in which the hydrogen at position 6 has been replaced by a beta-D-glucosyl residue. | swertisin |
| taraxasterol | A pentacyclic triterpenoid that is taraxastane with a beta-hydroxy group at position 3. | taraxasterol |
| tectorigenin | A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively. | tectorigenin |
| tempol | A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties. | 4-hydroxy-TEMPO |
| tetrahydroxycurcumin | A beta-diketone that is curcumin in which the two methoxy groups have been replaced by hydroxy groups. It is a metabolite of curcumin. | tetrahydroxycurcumin |
| theasinensin a | A biflavonoid that is obtained by coupling of two molecules of (-)-epigallocatechin 3-gallate resulting in a bond between positions C-2 of the hydroxyphenyl ring. It is a natural product found in oolong tea. | theasinensin A |
| theophylline | A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. | theophylline |
| thymoquinone | A member of the class of 1,4-benzoquinones that is 1,4-bezoquinone in which the hydrogens at positions 2 and 5 are replaced by methyl and isopropyl groups, respectively. It is a natural compound isolated from Nigella sativa which has demonstrated promising chemotherapeutic activity. | thymoquinone |
| tilorone | A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug. | tilorone |
| tocotrienol, delta | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2. | delta-tocotrienol |
| tramiprosate | An amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid. | 3-aminopropanesulfonic acid zwitterion; 3-aminopropanesulfonic acid |
| tretinoin | A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. | all-trans-retinoic acid |
| trilobatin | An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. | trilobatin |
| triptonide | A diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. | triptonide |
| u 69593 | A monocarboxylic acid amide obtained by formal condensation between the carboxy group of phenylacetic acid and the secodary amino group of (5R,7S,8S)-N-methyl-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-amine. | U69593 |
| ursodoxicoltaurine | A bile acid taurine conjugate derived from ursoodeoxycholic acid. | tauroursodeoxycholic acid |
| vanillin | A member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively. | vanillin |
| vestitol | A member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. | vestitol |
| viridiflorol | A carbotricyclic compound that is (1aS,4aR,7aR,7bR)-decahydro-1H-cyclopropa[e]azulene carrying four methyl substituents at positions 1, 1, 4 and 7 as well as a hydroxy substituent at position 4. It is a sesquiterpenoid isolated from several plant species and is a strong feeding deterrent for the melaleuca weevil that retards larval development. | viridiflorol |
| visnagin | A furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. | visnagin |
| zerumbone | A sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillation from a type of edible ginger, Zingiber zerumbet Smith, grown particularly in southeast Asia. | zerumbone |
| zingerone | A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger. | zingerone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 22.2577 | 1 | 28 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 11.8140 | 1 | 16 |
| 67.9K protein | Vaccinia virus | Potency | 13.7874 | 2 | 26 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 42.5185 | 4 | 20 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 31.5721 | 2 | 14 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 20.4510 | 1 | 37 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 33.1892 | 1 | 5 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 14.4176 | 1 | 8 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 15.1256 | 1 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 9.8960 | 1 | 8 |
| AR protein | Homo sapiens (human) | Potency | 15.3350 | 10 | 125 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 32.1579 | 3 | 39 |
| arylsulfatase A | Homo sapiens (human) | Potency | 15.2080 | 1 | 7 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 15.0168 | 13 | 35 |
| Ataxin-2 | Homo sapiens (human) | Potency | 22.6571 | 2 | 16 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 13.8621 | 4 | 19 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 27.7132 | 2 | 21 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 11.9955 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 7.9669 | 1 | 3 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 9.7718 | 2 | 3 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 21.5258 | 3 | 22 |
| BRCA1 | Homo sapiens (human) | Potency | 17.2496 | 1 | 5 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 51.7709 | 1 | 14 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 16.9469 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 30.4821 | 1 | 2 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 27.4617 | 1 | 9 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 75.0595 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 30.4821 | 1 | 2 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 75.0595 | 1 | 2 |
| Caspase-7 | Homo sapiens (human) | Potency | 18.8091 | 1 | 7 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 26.5064 | 3 | 31 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 15.1116 | 2 | 20 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 20.4739 | 1 | 34 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 23.5826 | 3 | 24 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 40.2251 | 2 | 9 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 12.5579 | 2 | 5 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 28.0828 | 1 | 9 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 25.0641 | 2 | 14 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 13.3328 | 2 | 26 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 44.0259 | 1 | 13 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 16.8791 | 3 | 42 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 13.6800 | 1 | 15 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 23.7396 | 1 | 24 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 13.3328 | 2 | 26 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 52.5090 | 2 | 14 |
| ClpP | Bacillus subtilis | Potency | 19.9526 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | Potency | 13.0341 | 2 | 6 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 13.5209 | 1 | 8 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 14.9833 | 1 | 11 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 16.9088 | 1 | 7 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 15.1200 | 1 | 5 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 13.3336 | 1 | 7 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 19.8422 | 2 | 54 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 15.4294 | 2 | 13 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 32.3104 | 1 | 13 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 9.0596 | 3 | 4 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 7.6726 | 1 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 12.8750 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 16.6573 | 1 | 4 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 20.1923 | 2 | 7 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 34.1287 | 1 | 10 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 32.6044 | 2 | 11 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 18.8876 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 41.9310 | 2 | 27 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 19.7945 | 2 | 39 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 2.8173 | 1 | 2 |
| endonuclease IV | Escherichia coli | Potency | 14.8933 | 2 | 6 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.5423 | 12 | 162 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 28.7311 | 3 | 25 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 17.9611 | 10 | 90 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 23.4781 | 1 | 33 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 15.7583 | 4 | 55 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 8.4936 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 27.5451 | 5 | 37 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 35.7061 | 2 | 22 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 18.4626 | 1 | 8 |
| G | Vesicular stomatitis virus | Potency | 16.9088 | 1 | 7 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| galactokinase | Homo sapiens (human) | Potency | 41.3752 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 19.8422 | 1 | 27 |
| geminin | Homo sapiens (human) | Potency | 12.1890 | 4 | 58 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.0497 | 3 | 36 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 12.4997 | 1 | 10 |
| GLS protein | Homo sapiens (human) | Potency | 13.4038 | 2 | 19 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 26.5798 | 1 | 12 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 21.9784 | 4 | 37 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 7.6787 | 2 | 3 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.7612 | 1 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 26.1002 | 2 | 14 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.7612 | 1 | 2 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.7612 | 1 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 34.8926 | 1 | 7 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 26.8105 | 2 | 8 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 15.0623 | 2 | 17 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 38.7910 | 2 | 15 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 34.3521 | 2 | 3 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 7.6787 | 2 | 3 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 15.8888 | 2 | 63 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 26.6332 | 1 | 12 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 8.3854 | 2 | 8 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 66.4272 | 2 | 10 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 27.8345 | 1 | 6 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 16.9088 | 1 | 7 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 3.8034 | 1 | 3 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 29.4178 | 4 | 8 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 55.6716 | 2 | 11 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 10.3172 | 2 | 20 |
| IDH1 | Homo sapiens (human) | Potency | 16.6611 | 1 | 11 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 35.8668 | 2 | 13 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 16.9088 | 1 | 14 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 12.7589 | 2 | 7 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 16.5047 | 1 | 10 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 16.5047 | 1 | 10 |
| Interferon beta | Homo sapiens (human) | Potency | 13.3261 | 3 | 54 |
| interleukin 8 | Homo sapiens (human) | Potency | 28.0757 | 1 | 3 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 11.5896 | 2 | 21 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 13.4189 | 1 | 15 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 23.8362 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 31.3451 | 5 | 25 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 14.8572 | 5 | 16 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 32.2190 | 1 | 10 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 15.4068 | 2 | 75 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 24.4402 | 3 | 17 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 8.6656 | 2 | 7 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 22.4782 | 3 | 9 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 21.4215 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 21.4215 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 6.4858 | 1 | 4 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 8.4074 | 2 | 6 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 14.3608 | 1 | 10 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 15.7869 | 1 | 6 |
| Nrf2 | Homo sapiens (human) | Potency | 14.1886 | 2 | 6 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 26.5731 | 4 | 47 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 10.3476 | 1 | 8 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 44.8659 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 34.6831 | 1 | 7 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 27.8196 | 1 | 6 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 37.1939 | 2 | 57 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 9.2069 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 30.5041 | 3 | 46 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 0.0157 | 1 | 2 |
| P53 | Homo sapiens (human) | Potency | 40.2941 | 1 | 4 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 45.4717 | 1 | 14 |
| Parkin | Homo sapiens (human) | Potency | 18.6593 | 2 | 6 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 47.5864 | 2 | 11 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 6.0118 | 2 | 8 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 40.6175 | 1 | 5 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 23.6882 | 5 | 49 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 28.8320 | 5 | 34 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 30.0170 | 2 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 49.2214 | 2 | 24 |
| PINK1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 10.2936 | 1 | 13 |
| Platelet-activating factor receptor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| polyprotein | Zika virus | Potency | 18.4626 | 1 | 8 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 13.9553 | 1 | 9 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 16.8849 | 1 | 15 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 11.1799 | 1 | 7 |
| PPM1D protein | Homo sapiens (human) | Potency | 12.5428 | 1 | 30 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 32.7420 | 3 | 25 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 28.9482 | 1 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 51.0605 | 2 | 10 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 25.7877 | 4 | 4 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 28.1838 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 0.0157 | 2 | 4 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 49.2933 | 1 | 5 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 78.1171 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 13.7947 | 2 | 31 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 80.5036 | 1 | 11 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 17.2711 | 1 | 11 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 20.8385 | 3 | 44 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 19.9134 | 4 | 56 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 24.8926 | 3 | 4 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 14.2457 | 3 | 9 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 14.8365 | 1 | 2 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 10.0000 | 1 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 34.9016 | 3 | 12 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 34.9016 | 3 | 12 |
| Smad3 | Homo sapiens (human) | Potency | 19.3875 | 1 | 15 |
| snurportin-1 | Homo sapiens (human) | Potency | 35.8668 | 2 | 13 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 22.4854 | 1 | 6 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 17.0195 | 1 | 22 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 22.5660 | 1 | 12 |
| TDP1 protein | Homo sapiens (human) | Potency | 16.5411 | 2 | 120 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 33.5030 | 1 | 5 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 29.5614 | 4 | 40 |
| Thrombopoietin | Homo sapiens (human) | Potency | 1.5621 | 2 | 8 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.5431 | 3 | 44 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 39.5760 | 4 | 19 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 29.0785 | 7 | 35 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 20.4002 | 2 | 7 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 11.4642 | 1 | 2 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 53.0804 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 4.3010 | 1 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 14.7475 | 2 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 10.2936 | 1 | 13 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 10.2936 | 1 | 13 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 37.6061 | 3 | 28 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 17.5072 | 2 | 16 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 27.7616 | 5 | 28 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 28.5590 | 5 | 33 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 30.3234 | 1 | 12 |
| Vpr | Human immunodeficiency virus 1 | Potency | 63.0957 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 29.5830 | 2 | 5 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [tau protein] kinase | Oryctolagus cuniculus (rabbit) | IC50 | 2.0000 | 1 | 1 |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 9.6995 | 2 | 2 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 3.0333 | 1 | 3 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 42.4493 | 4 | 14 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 62.0875 | 3 | 8 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 5.5150 | 1 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | IC50 | 0.0045 | 3 | 3 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | Ki | 35.5004 | 2 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | IC50 | 1.1315 | 8 | 8 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.1000 | 1 | 4 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 1.3000 | 2 | 2 |
| 3',5'-cyclic-AMP phosphodiesterase | Sus scrofa (pig) | IC50 | 0.0010 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 6,408.5500 | 2 | 2 |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 | Homo sapiens (human) | IC50 | 26.5000 | 1 | 2 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.0005 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 1.6390 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.4680 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 1.9510 | 2 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.3580 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.2280 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 3.2780 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.7170 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 3.2780 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.7170 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 350.0000 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | IC50 | 15.7850 | 2 | 4 |
| 5'-nucleotidase | Mus musculus (house mouse) | IC50 | 73.0367 | 2 | 3 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 6 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 42.4493 | 4 | 14 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 62.0875 | 3 | 8 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 5.1794 | 16 | 17 |
| 72 kDa type IV collagenase | Homo sapiens (human) | Ki | 0.0004 | 3 | 3 |
| A disintegrin and metalloproteinase with thrombospondin motifs 4 | Homo sapiens (human) | IC50 | 0.4800 | 1 | 1 |
| A disintegrin and metalloproteinase with thrombospondin motifs 5 | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 112.8520 | 5 | 5 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 182.9250 | 4 | 4 |
| Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | IC50 | 59.2000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | Ki | 100.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 83.0000 | 1 | 2 |
| Acrosin | Sus scrofa (pig) | Ki | 2.3000 | 1 | 1 |
| Acyl-CoA desaturase 1 | Rattus norvegicus (Norway rat) | Ki | 0.0035 | 1 | 1 |
| Adenosine receptor A1 | Bos taurus (cattle) | IC50 | 1,006,650,005.0433 | 3 | 3 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 17.1040 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 19.0000 | 2 | 2 |
| Adenosine receptor A1 | Bos taurus (cattle) | Ki | 4.1143 | 7 | 7 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | Ki | 21.3333 | 6 | 6 |
| Adenosine receptor A1 | Gallus gallus (chicken) | Ki | 6.0000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 4.8899 | 27 | 27 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 7.5636 | 44 | 53 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 6.0130 | 2 | 2 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Adenosine receptor A2a | Cavia porcellus (domestic guinea pig) | Ki | 14.0000 | 2 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 5.5200 | 42 | 42 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 11.6404 | 34 | 44 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 10.1290 | 21 | 21 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 12.7378 | 20 | 29 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.2750 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 36.2697 | 32 | 33 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | Ki | 37.2562 | 10 | 11 |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Homo sapiens (human) | IC50 | 8.2000 | 1 | 1 |
| albumin precursor | Bos taurus (cattle) | IC50 | 94.2660 | 1 | 1 |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | Ki | 0.4500 | 1 | 1 |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 6.0380 | 3 | 3 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 34.0282 | 10 | 11 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 2.6852 | 3 | 4 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 2.0605 | 2 | 4 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | IC50 | 17.1686 | 6 | 7 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | Ki | 0.0460 | 1 | 1 |
| Aldo-keto reductase family 1 member C1 | Homo sapiens (human) | IC50 | 21.1200 | 2 | 2 |
| Aldo-keto reductase family 1 member C2 | Homo sapiens (human) | IC50 | 15.8800 | 2 | 2 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 2.7050 | 2 | 2 |
| Aldo-keto reductase family 1 member C4 | Homo sapiens (human) | IC50 | 5.2750 | 2 | 2 |
| alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Ki | 82.0000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alpha-(1,3)-fucosyltransferase 7 | Homo sapiens (human) | IC50 | 26.5000 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.3375 | 2 | 2 |
| Alpha-1A adrenergic receptor | Bos taurus (cattle) | Ki | 0.0004 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.7458 | 2 | 4 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.5584 | 3 | 3 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.7458 | 2 | 4 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0004 | 1 | 3 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.3750 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.5160 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 15.6700 | 3 | 5 |
| Alpha-amylase 1A | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 251.4000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 28.0338 | 4 | 8 |
| Amiloride-sensitive amine oxidase [copper-containing] | Homo sapiens (human) | Ki | 0.2900 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 32.0103 | 9 | 9 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 0.7100 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 11.0780 | 9 | 9 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 21.5000 | 1 | 1 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 15.5000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 15.5000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 20.9877 | 37 | 38 |
| Androgen receptor | Homo sapiens (human) | IC50 | 152.1780 | 1 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 175.5940 | 1 | 3 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 0.0034 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 198.5738 | 3 | 3 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 12.8802 | 1 | 1 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 15.8202 | 6 | 8 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 100.3023 | 2 | 3 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | IC50 | 0.0170 | 1 | 1 |
| apelin receptor | Homo sapiens (human) | IC50 | 21.3000 | 1 | 1 |
| Apoptosis regulator BAX | Homo sapiens (human) | IC50 | 0.0230 | 1 | 1 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | IC50 | 0.9278 | 8 | 11 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | Ki | 0.0182 | 18 | 19 |
| Arginase | Leishmania amazonensis | Ki | 0.7000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 1.7502 | 4 | 4 |
| Aromatase | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Aspartyl/asparaginyl beta-hydroxylase | Homo sapiens (human) | IC50 | 3.4400 | 4 | 4 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 120.5500 | 1 | 6 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 42.1000 | 6 | 6 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 50.0000 | 4 | 4 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 28.5350 | 2 | 8 |
| B-cell CLL/lymphoma 9 protein | Homo sapiens (human) | IC50 | 5.2130 | 1 | 1 |
| B-cell CLL/lymphoma 9 protein | Homo sapiens (human) | Ki | 4.8780 | 3 | 3 |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | IC50 | 16.6890 | 3 | 3 |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | Ki | 0.0010 | 1 | 1 |
| Bcl-2-binding component 3, isoforms 1/2 | Homo sapiens (human) | IC50 | 0.0003 | 1 | 1 |
| Bcl-2-like protein 1 | Homo sapiens (human) | IC50 | 0.9279 | 18 | 22 |
| Bcl-2-like protein 1 | Homo sapiens (human) | Ki | 0.0644 | 35 | 36 |
| Bcl-2-like protein 10 | Homo sapiens (human) | Ki | 0.0010 | 1 | 1 |
| Bcl-2-like protein 11 | Homo sapiens (human) | IC50 | 0.0020 | 1 | 1 |
| Bcl-2-like protein 2 | Homo sapiens (human) | IC50 | 1.4573 | 4 | 7 |
| Bcl-2-like protein 2 | Homo sapiens (human) | Ki | 0.0578 | 5 | 5 |
| bcl-2-related protein A1 | Mus musculus (house mouse) | IC50 | 20.0000 | 1 | 1 |
| Bcl-2-related protein A1 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| Bcl2-associated agonist of cell death | Homo sapiens (human) | Ki | 0.0008 | 2 | 2 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 7.7510 | 1 | 1 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 3.6633 | 1 | 3 |
| Beta-casein | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 3 |
| Beta-casein | Bos taurus (cattle) | Ki | 0.0010 | 1 | 1 |
| Beta-glucuronidase | Escherichia coli K-12 | IC50 | 1.6000 | 1 | 1 |
| Beta-glucuronidase | Homo sapiens (human) | IC50 | 22.7000 | 2 | 2 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.0000 | 1 | 3 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 11.5000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 179.6520 | 5 | 5 |
| Beta-secretase 1 | Homo sapiens (human) | Ki | 5.1300 | 1 | 1 |
| BH3-interacting domain death agonist | Homo sapiens (human) | IC50 | 16.5242 | 2 | 2 |
| BH3-interacting domain death agonist | Homo sapiens (human) | Ki | 20.8000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 260.4786 | 3 | 14 |
| Botulinum neurotoxin type A | Clostridium botulinum | IC50 | 20.0000 | 1 | 1 |
| Botulinum neurotoxin type A | Clostridium botulinum | Ki | 14.3000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 14.1050 | 4 | 6 |
| Bromodomain testis-specific protein | Homo sapiens (human) | IC50 | 0.1902 | 13 | 13 |
| Bromodomain-containing protein 1 | Homo sapiens (human) | IC50 | 44.5000 | 1 | 1 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | IC50 | 0.0959 | 22 | 22 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | Ki | 0.0128 | 4 | 4 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | IC50 | 0.0573 | 18 | 18 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | Ki | 0.0078 | 4 | 4 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | IC50 | 0.8257 | 119 | 119 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | Ki | 0.0193 | 8 | 8 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 1.3963 | 3 | 3 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 1.6140 | 1 | 1 |
| C-C chemokine receptor type 5 | Homo sapiens (human) | IC50 | 0.0030 | 1 | 1 |
| C-C chemokine receptor type 5 | Mus musculus (house mouse) | IC50 | 0.0002 | 1 | 1 |
| C-C chemokine receptor type 7 | Homo sapiens (human) | IC50 | 0.0031 | 1 | 1 |
| Cadherin-1 | Homo sapiens (human) | Ki | 387.2000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | IC50 | 340.4000 | 5 | 5 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | IC50 | 300.5000 | 4 | 4 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | IC50 | 62.5364 | 2 | 11 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Calmodulin-1 | Homo sapiens (human) | IC50 | 33.4300 | 1 | 1 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Homo sapiens (human) | IC50 | 36.7900 | 1 | 10 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | IC50 | 109.3832 | 19 | 21 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | IC50 | 6.5900 | 1 | 4 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | Ki | 75.7152 | 7 | 7 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | Ki | 265.0130 | 2 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 68.8597 | 25 | 36 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | IC50 | 6.5900 | 1 | 4 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | Ki | 75.7152 | 7 | 7 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | Ki | 265.0130 | 2 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | IC50 | 95.5529 | 18 | 20 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | IC50 | 6.5900 | 1 | 4 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | Ki | 75.7152 | 7 | 7 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | Ki | 265.0130 | 2 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 67.0278 | 23 | 34 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | Ki | 75.7152 | 7 | 7 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | IC50 | 6.5900 | 1 | 4 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | Ki | 265.0130 | 2 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 7B | Homo sapiens (human) | IC50 | 36.7900 | 1 | 10 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 121.1429 | 2 | 7 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 3.3100 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 0.6767 | 16 | 17 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 3.6328 | 6 | 6 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | IC50 | 1.7709 | 2 | 2 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 0.1862 | 27 | 28 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 375.5000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 42.8612 | 7 | 17 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 6.6044 | 6 | 8 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 9.7650 | 1 | 2 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 12.2000 | 2 | 2 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 9.4300 | 2 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 252.4800 | 2 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 53.1777 | 7 | 17 |
| Carbonic anhydrase 2 | Mycobacterium tuberculosis H37Rv | Ki | 3.6633 | 1 | 3 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 8.3675 | 1 | 8 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 11.1000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 7.1428 | 4 | 11 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | IC50 | 8.8600 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 7.0400 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 10.5000 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 8.4500 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 3.1552 | 3 | 5 |
| Carbonic anhydrase 9 | Homo sapiens (human) | IC50 | 9.3900 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 3.2420 | 4 | 5 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | Ki | 0.1100 | 1 | 1 |
| Carboxypeptidase A1 | Bos taurus (cattle) | IC50 | 27.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 11.8683 | 6 | 12 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 3.9650 | 3 | 4 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 5.0083 | 2 | 6 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | Ki | 7.6700 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 11.0323 | 7 | 13 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Ki | 3.9200 | 2 | 2 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 11.0323 | 7 | 13 |
| Casein kinase II subunit beta | Homo sapiens (human) | Ki | 3.9200 | 2 | 2 |
| Caspase-1 | Homo sapiens (human) | IC50 | 1.3850 | 1 | 2 |
| Catenin beta-1 | Homo sapiens (human) | IC50 | 5.2130 | 1 | 1 |
| Catenin beta-1 | Homo sapiens (human) | Ki | 4.8780 | 3 | 3 |
| Cathepsin G | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 73.0500 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 2.8100 | 2 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.1010 | 1 | 1 |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | IC50 | 0.5233 | 3 | 3 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 52.5364 | 2 | 11 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 300.0000 | 2 | 2 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 80.6583 | 3 | 12 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 33.6000 | 2 | 11 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 6.1000 | 1 | 1 |
| Chain A, Apoptosis regulator Bcl-X | Homo sapiens (human) | Ki | 0.0005 | 1 | 1 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 0.0000 | 1 | 14 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 0.0000 | 1 | 8 |
| Chain A, Casein Kinase Ii Subunit Alpha | Zea mays | IC50 | 0.3500 | 1 | 3 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 0.5667 | 1 | 6 |
| Chain A, Exotoxin A | Pseudomonas aeruginosa | Ki | 0.1400 | 1 | 1 |
| Chain A, Extracellular Regulated Kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 9.0095 | 1 | 4 |
| Chain A, Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | Ki | 19.0100 | 1 | 2 |
| Chain A, MAP KINASE P38 | Homo sapiens (human) | IC50 | 9.0095 | 1 | 2 |
| Chain A, Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 0.0058 | 1 | 2 |
| Chain A, NAD-dependent deacetylase | Thermotoga maritima | IC50 | 1,000.0000 | 1 | 1 |
| Chain A, Nuclear Receptor ROR-beta | Rattus norvegicus (Norway rat) | Ki | 0.2800 | 1 | 1 |
| Chain A, Pancreatic alpha-amylase | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 2 |
| Chain A, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform | Homo sapiens (human) | IC50 | 0.0080 | 1 | 2 |
| Chain A, PROTEIN (MAP KINASE P38) | Homo sapiens (human) | IC50 | 9.0095 | 1 | 6 |
| Chain A, Pyridoxal Kinase | Homo sapiens (human) | Ki | 50.0000 | 1 | 2 |
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | IC50 | 35.0600 | 1 | 1 |
| Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 0.0000 | 1 | 2 |
| Chain B, Cell division protein kinase 6 | Homo sapiens (human) | IC50 | 0.8500 | 1 | 1 |
| Chemotaxis protein CheA | Escherichia coli K-12 | IC50 | 111.0000 | 1 | 1 |
| Chitotriosidase-1 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 2 |
| Cholinesterase | Equus caballus (horse) | IC50 | 200.0000 | 2 | 2 |
| Cholinesterase | Homo sapiens (human) | IC50 | 172.2500 | 4 | 4 |
| Cholinesterase | Equus caballus (horse) | Ki | 100.0000 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| Class A sortase SrtA | Staphylococcus aureus | IC50 | 20.0560 | 5 | 5 |
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | Homo sapiens (human) | IC50 | 26.5000 | 1 | 2 |
| Coagulation factor VII | Homo sapiens (human) | Ki | 8,000.0000 | 1 | 1 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 5.2850 | 2 | 2 |
| Coagulation factor X | Homo sapiens (human) | Ki | 0.5700 | 1 | 1 |
| Cocaine esterase | Homo sapiens (human) | Ki | 0.1090 | 1 | 1 |
| Collagenase 3 | Homo sapiens (human) | IC50 | 2.5152 | 4 | 4 |
| Collagenase ColH | Hathewaya histolytica | IC50 | 0.0240 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 18.4494 | 7 | 7 |
| Cruzipain | Trypanosoma cruzi | IC50 | 81.8333 | 6 | 6 |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | IC50 | 28.0692 | 1 | 12 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 7.3000 | 3 | 3 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 143.0620 | 6 | 10 |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | IC50 | 28.0692 | 1 | 12 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 9.3800 | 4 | 5 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 22.9533 | 2 | 15 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 42.9120 | 2 | 15 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 0.3000 | 3 | 3 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 22.9533 | 2 | 15 |
| Cyclin-G-associated kinase | Homo sapiens (human) | IC50 | 0.1360 | 1 | 1 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 0.3000 | 3 | 3 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 7.7500 | 1 | 1 |
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | IC50 | 30.2500 | 1 | 1 |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 0.7080 | 2 | 4 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.9323 | 3 | 9 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 33.2335 | 7 | 10 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 0.1544 | 2 | 5 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.3760 | 4 | 10 |
| Cytochrome P450 2A6 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 81.2500 | 3 | 4 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 52.5607 | 5 | 7 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 9.2000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 51.2778 | 6 | 9 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 42.1190 | 11 | 14 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 8.7767 | 3 | 3 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 78.9200 | 2 | 3 |
| Cytochrome P450 3A7 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Cytosol aminopeptidase | Sus scrofa (pig) | IC50 | 49.6000 | 1 | 1 |
| Cytosolic phospholipase A2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| D-amino-acid oxidase | Sus scrofa (pig) | IC50 | 1.0700 | 2 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 4.4120 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 2.2060 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 3.7290 | 1 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.8652 | 2 | 3 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.0006 | 1 | 1 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 90.7200 | 2 | 5 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 3.6437 | 4 | 6 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 14.5600 | 2 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 6.7140 | 11 | 14 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 1.0000 | 2 | 2 |
| Diacylglycerol lipase-alpha | Homo sapiens (human) | IC50 | 63.6500 | 1 | 2 |
| Diamine acetyltransferase 1 | Homo sapiens (human) | Ki | 2.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 405.7535 | 1 | 2 |
| Dipeptidyl peptidase 3 | Homo sapiens (human) | IC50 | 63.7500 | 1 | 4 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 100.0600 | 2 | 2 |
| Dipeptidyl peptidase 4 | Sus scrofa (pig) | IC50 | 0.4900 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 10 | Homo sapiens (human) | IC50 | 0.1356 | 2 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 12 | Homo sapiens (human) | IC50 | 0.0059 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | IC50 | 0.1125 | 3 | 3 |
| Disintegrin and metalloproteinase domain-containing protein 9 | Homo sapiens (human) | IC50 | 0.0286 | 2 | 2 |
| DNA damage-inducible transcript 3 protein | Mus musculus (house mouse) | IC50 | 6.3050 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | IC50 | 41.1833 | 3 | 3 |
| DNA polymerase beta | Rattus norvegicus (Norway rat) | IC50 | 10.2500 | 2 | 2 |
| DNA primase | Mycobacterium tuberculosis CDC1551 | IC50 | 38.0500 | 1 | 2 |
| DNA topoisomerase 1 | Homo sapiens (human) | IC50 | 250.0000 | 1 | 1 |
| DNA topoisomerase 1 | Rattus norvegicus (Norway rat) | IC50 | 2.8300 | 2 | 2 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 144.3000 | 2 | 2 |
| DNA-3-methyladenine glycosylase | Homo sapiens (human) | IC50 | 2.6000 | 1 | 1 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 1,500.0000 | 1 | 1 |
| Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | Homo sapiens (human) | IC50 | 36.7900 | 1 | 10 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | IC50 | 0.0700 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 0.8150 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | IC50 | 0.0800 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| E3 ubiquitin-protein ligase TRIM33 | Homo sapiens (human) | IC50 | 0.3256 | 1 | 1 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | Mus musculus (house mouse) | IC50 | 25.6600 | 1 | 2 |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Homo sapiens (human) | IC50 | 10.3000 | 1 | 1 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Endochitinase B1 | Aspergillus fumigatus | IC50 | 1,000.0000 | 1 | 2 |
| Endothelin-1 receptor | Sus scrofa (pig) | IC50 | 0.0010 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | Ki | 7.0500 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.2000 | 2 | 5 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 2.1000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 2.6338 | 12 | 12 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 2.0152 | 4 | 4 |
| Estrogen receptor | Homo sapiens (human) | Ki | 2.2600 | 1 | 1 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 0.0814 | 3 | 4 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 | 2.9272 | 1 | 2 |
| Farnesyl pyrophosphate synthase | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 26.4133 | 3 | 3 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 62.5000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 11.2000 | 3 | 3 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 4.1540 | 4 | 5 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 18.8500 | 1 | 2 |
| Furin | Homo sapiens (human) | IC50 | 0.0180 | 1 | 1 |
| Furin | Homo sapiens (human) | Ki | 3.4394 | 1 | 6 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | IC50 | 8.7000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 9.8024 | 3 | 5 |
| G-protein coupled receptor 55 | Homo sapiens (human) | IC50 | 2.6423 | 1 | 1 |
| G-protein coupled receptor 84 | Homo sapiens (human) | Ki | 1.7800 | 1 | 1 |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | IC50 | 28.0692 | 1 | 12 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 47.8467 | 5 | 9 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 24.8180 | 3 | 5 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 24.8180 | 3 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 3.2145 | 1 | 3 |
| Genome polyprotein | Coxsackievirus B3 (strain Nancy) | IC50 | 1.1000 | 1 | 1 |
| Genome polyprotein | | IC50 | 1.6000 | 1 | 1 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 150.0000 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 53.0000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 19.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 54.6667 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 19.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 45.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | IC50 | 62.0000 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 69.0000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | Trypanosoma cruzi | IC50 | 149.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Rattus norvegicus (Norway rat) | IC50 | 99.0000 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 51.6168 | 5 | 16 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 3.4840 | 3 | 5 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 5.8140 | 24 | 29 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 25.9151 | 2 | 13 |
| Group 10 secretory phospholipase A2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | IC50 | 1.6300 | 1 | 1 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Hepatocyte growth factor activator | Homo sapiens (human) | IC50 | 32.0000 | 1 | 1 |
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | Homo sapiens (human) | IC50 | 36.7900 | 1 | 10 |
| histidine kinase | Streptococcus pneumoniae TIGR4 | IC50 | 216.0000 | 1 | 1 |
| Histone acetyltransferase KAT2B | Homo sapiens (human) | IC50 | 19.4500 | 4 | 4 |
| Histone acetyltransferase KAT5 | Homo sapiens (human) | IC50 | 64.0000 | 1 | 1 |
| Histone acetyltransferase KAT8 | Homo sapiens (human) | IC50 | 43.0000 | 1 | 1 |
| Histone acetyltransferase KAT8 | Homo sapiens (human) | Ki | 64.0000 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 16.4136 | 10 | 11 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 50.7900 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 97.6700 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 64.9800 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 6.0500 | 1 | 2 |
| Homeobox protein Nkx-2.5 | Mus musculus (house mouse) | IC50 | 22.0000 | 1 | 1 |
| Hyaluronidase-1 | Homo sapiens (human) | IC50 | 2,000.0000 | 1 | 1 |
| hypothetical protein SA1422 | Staphylococcus aureus subsp. aureus N315 | IC50 | 42.9000 | 2 | 2 |
| Ileal sodium/bile acid cotransporter | Homo sapiens (human) | Ki | 28.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 0.7200 | 4 | 4 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 301.3000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.1000 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 28.7000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 12.1156 | 8 | 14 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 21.7841 | 8 | 10 |
| Inhibin alpha chain | Homo sapiens (human) | IC50 | 5.2000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 3.8900 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 1.3333 | 1 | 3 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 8.9000 | 1 | 3 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 31.0810 | 13 | 31 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 12.2310 | 2 | 4 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 0.6083 | 12 | 13 |
| Interstitial collagenase | Homo sapiens (human) | Ki | 0.0004 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 18.7000 | 1 | 1 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Islet amyloid polypeptide | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Kallikrein-1 | Homo sapiens (human) | IC50 | 34.1000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 50.1333 | 3 | 5 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 0.0580 | 4 | 5 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0006 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0046 | 3 | 4 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 0.2420 | 13 | 38 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0026 | 5 | 5 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | Ki | 6.5000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 9.3500 | 1 | 2 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 31.6409 | 2 | 4 |
| large T antigen | Betapolyomavirus macacae | IC50 | 10.9033 | 1 | 3 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 12.2310 | 2 | 4 |
| Linoleate 9S-lipoxygenase-4 | Glycine max (soybean) | IC50 | 22.0000 | 1 | 1 |
| Liver carboxylesterase 1 | Homo sapiens (human) | Ki | 1.2200 | 1 | 1 |
| Low molecular weight phosphotyrosine protein phosphatase | Bos taurus (cattle) | IC50 | 10.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 3.0000 | 1 | 2 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | Ki | 3.9400 | 1 | 2 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 11.0086 | 5 | 7 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| M-phase inducer phosphatase 1 | Homo sapiens (human) | IC50 | 13.4000 | 2 | 2 |
| M1-family alanyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 22.8600 | 1 | 1 |
| Macrophage metalloelastase | Homo sapiens (human) | IC50 | 0.1275 | 8 | 8 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 20.2375 | 3 | 8 |
| Macrophage migration inhibitory factor | Plasmodium falciparum 3D7 | IC50 | 10.0000 | 1 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.6920 | 1 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.4155 | 1 | 2 |
| Matrilysin | Homo sapiens (human) | IC50 | 13.2595 | 3 | 4 |
| Matrix metalloproteinase-14 | Homo sapiens (human) | IC50 | 0.0102 | 10 | 10 |
| Matrix metalloproteinase-15 | Homo sapiens (human) | IC50 | 0.0060 | 2 | 2 |
| Matrix metalloproteinase-16 | Homo sapiens (human) | IC50 | 0.0080 | 2 | 2 |
| Matrix metalloproteinase-17 | Homo sapiens (human) | IC50 | 0.0034 | 1 | 1 |
| Matrix metalloproteinase-26 | Homo sapiens (human) | IC50 | 0.0170 | 2 | 2 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 3.9407 | 15 | 15 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | Ki | 0.0004 | 2 | 2 |
| Mcl-1 | Homo sapiens (human) | IC50 | 2.9883 | 1 | 1 |
| Melanocortin receptor 3 | Homo sapiens (human) | IC50 | 0.0323 | 4 | 4 |
| Melanocortin receptor 3 | Homo sapiens (human) | Ki | 0.0460 | 1 | 1 |
| Melanocortin receptor 4 | Homo sapiens (human) | IC50 | 0.0176 | 6 | 6 |
| Melanocortin receptor 4 | Homo sapiens (human) | Ki | 0.0846 | 12 | 12 |
| Melanocortin receptor 5 | Homo sapiens (human) | IC50 | 0.1778 | 4 | 4 |
| Melanocortin receptor 5 | Homo sapiens (human) | Ki | 0.1500 | 1 | 1 |
| Melanocyte-stimulating hormone receptor | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Melanocyte-stimulating hormone receptor | Homo sapiens (human) | Ki | 0.0015 | 1 | 1 |
| microphthalmia-associated transcription factor isoform 9 | Homo sapiens (human) | IC50 | 6.3810 | 3 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 54.8750 | 4 | 4 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 6.7540 | 2 | 3 |
| Mitogen-activated protein kinase 1 | Rattus norvegicus (Norway rat) | IC50 | 9.0095 | 1 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 21.0211 | 1 | 18 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 0.0190 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Ki | 0.0400 | 1 | 1 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 0.0190 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 0.0190 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 12.7991 | 11 | 31 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 0.0044 | 2 | 2 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Ki | 400.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.5880 | 2 | 3 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 0.1940 | 3 | 4 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.2354 | 6 | 12 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 2.7538 | 8 | 8 |
| Mu-type opioid receptor | Mus musculus (house mouse) | Ki | 0.2885 | 5 | 7 |
| Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Homo sapiens (human) | IC50 | 1.5500 | 2 | 2 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 2.0025 | 3 | 4 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 8.6000 | 2 | 3 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 115.3000 | 1 | 6 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 1.4250 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.5070 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 1.5800 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.2200 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 2.8850 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 2.0730 | 1 | 1 |
| N-acylethanolamine-hydrolyzing acid amidase | Homo sapiens (human) | IC50 | 75.0000 | 1 | 2 |
| NACHT, LRR and PYD domains-containing protein 3 | Homo sapiens (human) | IC50 | 24.2000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| NAD | Homo sapiens (human) | IC50 | 5.4667 | 3 | 3 |
| NAD-dependent histone deacetylase SIR2 | Saccharomyces cerevisiae S288C | IC50 | 55.3333 | 3 | 3 |
| NAD-dependent protein deacetylase | Schistosoma mansoni | IC50 | 221.5500 | 2 | 2 |
| NAD-dependent protein deacetylase HST2 | Saccharomyces cerevisiae S288C | IC50 | 69.5000 | 1 | 2 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 112.4080 | 22 | 25 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 41.6467 | 26 | 30 |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | IC50 | 78.4571 | 7 | 7 |
| NAD-dependent protein deacetylase sirtuin-6 | Homo sapiens (human) | IC50 | 173.3500 | 4 | 4 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 70.5833 | 4 | 6 |
| NAD(+) hydrolase SARM1 | Homo sapiens (human) | IC50 | 43.8000 | 1 | 1 |
| NADPH oxidase 4 | Homo sapiens (human) | IC50 | 0.8500 | 1 | 1 |
| NADPH--cytochrome P450 reductase | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/RI/5+/1957(H2N2)) | IC50 | 11.9000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 56.6976 | 7 | 17 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 16.6500 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neuronal proto-oncogene tyrosine-protein kinase Src | Mus musculus (house mouse) | IC50 | 2.2000 | 1 | 1 |
| Neutrophil collagenase | Homo sapiens (human) | IC50 | 0.0054 | 2 | 2 |
| Neutrophil collagenase | Homo sapiens (human) | Ki | 0.0002 | 2 | 2 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 34.2250 | 4 | 4 |
| Neutrophil elastase | Homo sapiens (human) | Ki | 10.1000 | 1 | 1 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 17.8250 | 3 | 4 |
| Nociceptin receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.6920 | 1 | 1 |
| Nociceptin receptor | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Non-lysosomal glucosylceramidase | Homo sapiens (human) | IC50 | 19.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | IC50 | 13.4794 | 13 | 15 |
| Non-structural protein 1 | Dengue virus | IC50 | 1.7000 | 1 | 1 |
| Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Nuclear receptor ROR-alpha | Homo sapiens (human) | IC50 | 0.1995 | 1 | 1 |
| Nuclear receptor ROR-beta | Homo sapiens (human) | IC50 | 12.6224 | 2 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | IC50 | 0.1995 | 1 | 1 |
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | IC50 | 45.3456 | 1 | 3 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 15.7215 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 12.8802 | 1 | 1 |
| P2X purinoceptor 7 | Homo sapiens (human) | IC50 | 0.8300 | 1 | 1 |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | IC50 | 25.5000 | 1 | 1 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 18.8000 | 2 | 3 |
| Pancreatic alpha-amylase | Sus scrofa (pig) | IC50 | 157.9667 | 2 | 3 |
| Pancreatic triacylglycerol lipase | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 87.2000 | 2 | 2 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | IC50 | 0.8200 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Ki | 0.8200 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 9.1670 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 10.2320 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Ki | 22.0000 | 1 | 1 |
| Phosphatidylcholine 2-acylhydrolase | Apis mellifera (honey bee) | IC50 | 0.0700 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 0.1396 | 2 | 5 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | IC50 | 0.6676 | 2 | 5 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | IC50 | 0.1876 | 2 | 5 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 363.0829 | 5 | 8 |
| Phosphodiesterase | Bos taurus (cattle) | IC50 | 250.3333 | 6 | 6 |
| Phosphodiesterase | Bos taurus (cattle) | Ki | 77.0000 | 1 | 1 |
| Phosphodiesterase isozyme 4 | Homo sapiens (human) | IC50 | 125.0000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Phospholipase A2 | Apis mellifera (honey bee) | IC50 | 0.0700 | 1 | 1 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 11.1000 | 1 | 1 |
| Phospholipase A2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Phospholipase A2, membrane associated | Homo sapiens (human) | IC50 | 3.5000 | 1 | 1 |
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | IC50 | 1.9210 | 1 | 1 |
| Plasminogen | Homo sapiens (human) | IC50 | 28.4000 | 3 | 5 |
| Plasminogen | Rattus norvegicus (Norway rat) | IC50 | 2.6200 | 1 | 1 |
| Platelet-activating factor receptor | Cavia porcellus (domestic guinea pig) | IC50 | 200.0000 | 1 | 1 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | IC50 | 50.7453 | 18 | 26 |
| Poly [ADP-ribose] polymerase 2 | Homo sapiens (human) | IC50 | 0.1687 | 3 | 5 |
| Poly [ADP-ribose] polymerase 2 | Mus musculus (house mouse) | IC50 | 64.7825 | 1 | 4 |
| Poly [ADP-ribose] polymerase tankyrase-1 | Homo sapiens (human) | IC50 | 1.4307 | 5 | 8 |
| Poly [ADP-ribose] polymerase tankyrase-2 | Homo sapiens (human) | IC50 | 1.2162 | 4 | 7 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 93.6455 | 2 | 2 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 1,070.6000 | 4 | 5 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 31.4317 | 9 | 12 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 87.5000 | 3 | 4 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | IC50 | 23.9014 | 2 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Ki | 1.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 24.6033 | 4 | 9 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 3.9750 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | IC50 | 63.4227 | 3 | 11 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 32.6443 | 4 | 5 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 12.8802 | 1 | 1 |
| Probable linoleate 9S-lipoxygenase 5 | Solanum tuberosum (potato) | IC50 | 43.0000 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 8.8560 | 2 | 3 |
| Procathepsin L | Homo sapiens (human) | Ki | 3.4394 | 1 | 6 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 4.2800 | 4 | 5 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 127.0888 | 4 | 6 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 58.3400 | 6 | 7 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 0.0030 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 0.0006 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 44.2445 | 10 | 11 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 16.3733 | 3 | 3 |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | IC50 | 0.0006 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 93.9800 | 3 | 3 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 5.6333 | 4 | 6 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 81.0000 | 2 | 2 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 582.0000 | 1 | 1 |
| Protein E6 | Human papillomavirus 16 | IC50 | 4.0000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 5.5500 | 2 | 2 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 150.0000 | 1 | 2 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | IC50 | 49.2136 | 5 | 5 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 150.0000 | 1 | 2 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | IC50 | 36.5170 | 4 | 4 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 2 | 2 |
| Protein mono-ADP-ribosyltransferase PARP10 | Homo sapiens (human) | IC50 | 6.3123 | 2 | 4 |
| Protein mono-ADP-ribosyltransferase PARP12 | Homo sapiens (human) | IC50 | 0.2269 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP14 | Homo sapiens (human) | IC50 | 4.1843 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP15 | Homo sapiens (human) | IC50 | 10.9708 | 2 | 3 |
| Protein mono-ADP-ribosyltransferase PARP3 | Homo sapiens (human) | IC50 | 1.4377 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP4 | Homo sapiens (human) | IC50 | 0.7586 | 1 | 1 |
| Protein S100-B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 1 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 2 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 3 | Homo sapiens (human) | IC50 | 35.8333 | 3 | 3 |
| Protein-glutamine gamma-glutamyltransferase 2 | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Proteinase-activated receptor 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Proteinase-activated receptor 2 | Homo sapiens (human) | IC50 | 3.3012 | 2 | 2 |
| Proteinase-activated receptor 4 | Homo sapiens (human) | IC50 | 0.3800 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | IC50 | 10.7993 | 3 | 3 |
| Prothrombin | Homo sapiens (human) | Ki | 3.4394 | 1 | 6 |
| Prothrombin | Bos taurus (cattle) | IC50 | 0.0800 | 2 | 2 |
| Prothrombin | Bos taurus (cattle) | Ki | 3.9000 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 7,100.0000 | 1 | 1 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 6.1500 | 2 | 2 |
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | IC50 | 32.3400 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 9.6000 | 1 | 1 |
| Receptor protein-tyrosine kinase | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 10.4547 | 4 | 4 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 3.2843 | 4 | 7 |
| Receptor-type tyrosine-protein phosphatase eta | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase F | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase S | Homo sapiens (human) | IC50 | 7.3000 | 1 | 2 |
| Renin | Homo sapiens (human) | Ki | 2.3250 | 1 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 13.2750 | 1 | 2 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 11.0917 | 2 | 6 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 13.2750 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 11.6953 | 19 | 39 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 22.9825 | 3 | 12 |
| Retinoic acid receptor alpha | Homo sapiens (human) | IC50 | 2.2542 | 4 | 4 |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | IC50 | 0.0057 | 3 | 3 |
| Retinoic acid receptor alpha | Homo sapiens (human) | Ki | 0.0688 | 3 | 3 |
| Retinoic acid receptor beta | Homo sapiens (human) | IC50 | 0.7537 | 4 | 4 |
| Retinoic acid receptor beta | Mus musculus (house mouse) | IC50 | 0.0050 | 2 | 2 |
| Retinoic acid receptor beta | Homo sapiens (human) | Ki | 0.0095 | 3 | 3 |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | IC50 | 0.0040 | 2 | 2 |
| Retinoic acid receptor gamma | Homo sapiens (human) | IC50 | 0.0064 | 3 | 3 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Ki | 0.0056 | 4 | 4 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Mus musculus (house mouse) | IC50 | 18.0000 | 3 | 3 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 0.2268 | 3 | 3 |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor RXR-beta | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | Ki | 0.3118 | 3 | 3 |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | IC50 | 0.3500 | 1 | 1 |
| Retinoic acid receptor RXR-gamma | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | Ki | 0.1365 | 3 | 3 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Ki | 0.3500 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 5.1000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 3.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | Ki | 8.6000 | 1 | 1 |
| Secreted chorismate mutase | Mycobacterium tuberculosis H37Rv | IC50 | 24.8000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 16.8200 | 5 | 5 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | Ki | 70.5500 | 2 | 2 |
| Serine protease hepsin | Homo sapiens (human) | IC50 | 0.0235 | 2 | 2 |
| Serine protease hepsin | Homo sapiens (human) | Ki | 3.4394 | 1 | 6 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 16.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 4.2671 | 4 | 7 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 7.9267 | 3 | 3 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 164.3600 | 2 | 2 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 45.0000 | 2 | 2 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 5.5362 | 2 | 4 |
| Sialidase | Clostridium perfringens | Ki | 0.1748 | 2 | 2 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 383.3333 | 1 | 3 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 7.9000 | 1 | 1 |
| Signal transducer and activator of transcription 3 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | IC50 | 3.5316 | 20 | 38 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 7.5795 | 2 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 2.5100 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 68.6670 | 2 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 2.9760 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 109.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 22.1000 | 1 | 1 |
| Solute carrier family 22 member 12 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Solute carrier family 22 member 12 | Rattus norvegicus (Norway rat) | IC50 | 18.0000 | 1 | 1 |
| Solute carrier family 22 member 12 | Homo sapiens (human) | Ki | 5.7400 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 8.8500 | 1 | 2 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 9.5000 | 1 | 1 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Ki | 0.1200 | 1 | 1 |
| Solute carrier family 28 member 3 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 3.8250 | 4 | 4 |
| Sorbitol dehydrogenase | Homo sapiens (human) | IC50 | 212.0000 | 1 | 1 |
| Sortase A | Streptococcus mutans | IC50 | 18.7000 | 1 | 2 |
| Sphingosine 1-phosphate receptor 1 | Homo sapiens (human) | IC50 | 1.0000 | 2 | 2 |
| Sphingosine 1-phosphate receptor 2 | Homo sapiens (human) | IC50 | 0.0401 | 6 | 6 |
| Sphingosine 1-phosphate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Sphingosine 1-phosphate receptor 3 | Homo sapiens (human) | IC50 | 1.0000 | 2 | 2 |
| Sphingosine 1-phosphate receptor 4 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Sphingosine 1-phosphate receptor 5 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 13.2750 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 13.2750 | 1 | 2 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 2 | 2 |
| steroidogenic factor 1 | Homo sapiens (human) | IC50 | 67.5797 | 1 | 3 |
| Sterol O-acyltransferase 2 | Homo sapiens (human) | IC50 | 41.6000 | 1 | 1 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 1.6294 | 10 | 10 |
| Stromelysin-1 | Homo sapiens (human) | Ki | 0.0265 | 2 | 2 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 56.4250 | 1 | 4 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 56.4250 | 1 | 4 |
| Succinate-semialdehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 15.6000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 43.5000 | 2 | 2 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 247.3333 | 3 | 3 |
| SUMO-1 | Homo sapiens (human) | IC50 | 40.6500 | 2 | 2 |
| SUMO-activating enzyme subunit 1 | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| SUMO-conjugating enzyme UBC9 | Homo sapiens (human) | IC50 | 11.2000 | 2 | 2 |
| SUMO1 activating enzyme subunit 1 | Homo sapiens (human) | IC50 | 11.2000 | 2 | 2 |
| Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 1.1600 | 1 | 1 |
| Taste receptor type 2 member 31 | Homo sapiens (human) | IC50 | 11.3000 | 1 | 1 |
| TCRAV4S1, partial | Homo sapiens (human) | IC50 | 94.2660 | 1 | 1 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 9.4000 | 3 | 3 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 75.8733 | 2 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 189.5000 | 1 | 2 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 156.5000 | 1 | 2 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 52.1533 | 1 | 6 |
| Thyroid hormone receptor beta | Rattus norvegicus (Norway rat) | Ki | 14.0000 | 1 | 1 |
| Tissue alpha-L-fucosidase | Bos taurus (cattle) | IC50 | 32.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0132 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | Ki | 8,000.0000 | 1 | 1 |
| toll-like receptor 9 | Homo sapiens (human) | IC50 | 8.3620 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 19.7000 | 1 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 4.3740 | 1 | 1 |
| Transcription factor 7-like 2 | Homo sapiens (human) | Ki | 387.2000 | 1 | 1 |
| Transcription factor GATA-4 | Mus musculus (house mouse) | IC50 | 22.0000 | 1 | 1 |
| Transcription factor p65 | Homo sapiens (human) | IC50 | 7.6000 | 2 | 3 |
| Transcription intermediary factor 1-alpha | Homo sapiens (human) | IC50 | 0.1620 | 1 | 1 |
| Transcriptional activator Myb | Gallus gallus (chicken) | IC50 | 2.3707 | 1 | 2 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | IC50 | 13.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | IC50 | 10.2500 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 0.2100 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Rattus norvegicus (Norway rat) | IC50 | 0.3300 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 7 | Mus musculus (house mouse) | IC50 | 0.7600 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 8 | Homo sapiens (human) | IC50 | 0.1600 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 8 | Rattus norvegicus (Norway rat) | IC50 | 0.1600 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | IC50 | 4.8200 | 6 | 7 |
| Transient receptor potential cation channel subfamily V member 2 | Homo sapiens (human) | IC50 | 1.5000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 1.5000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 3 | Homo sapiens (human) | IC50 | 66.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 4 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 8.8560 | 2 | 3 |
| Transmembrane protease serine 2 | Homo sapiens (human) | Ki | 3.4394 | 1 | 6 |
| Transmembrane protease serine 6 | Homo sapiens (human) | IC50 | 0.0180 | 1 | 1 |
| Transmembrane protease serine 6 | Homo sapiens (human) | Ki | 3.4394 | 1 | 6 |
| Transthyretin | Homo sapiens (human) | IC50 | 68.8000 | 2 | 3 |
| Triosephosphate isomerase | Oryctolagus cuniculus (rabbit) | Ki | 2.6000 | 1 | 1 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 22.2924 | 4 | 6 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 1.8518 | 2 | 2 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 1.8518 | 2 | 2 |
| Tubulin alpha-1A chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | IC50 | 4.6759 | 28 | 28 |
| Tubulin alpha-1A chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | Ki | 5.7500 | 1 | 1 |
| Tubulin alpha-1B chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin alpha-1B chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin alpha-1C chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin alpha-1C chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin alpha-3C chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin alpha-3C chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin alpha-3E chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin alpha-3E chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin alpha-4A chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin alpha-4A chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta chain | Homo sapiens (human) | IC50 | 22.1326 | 42 | 43 |
| Tubulin beta chain | Sus scrofa (pig) | IC50 | 4.8445 | 26 | 26 |
| Tubulin beta chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta chain | Sus scrofa (pig) | Ki | 5.7500 | 1 | 1 |
| Tubulin beta-1 chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-1 chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-2A chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-2A chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-2B chain | Bos taurus (cattle) | IC50 | 469.7233 | 24 | 24 |
| Tubulin beta-2B chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-2B chain | Bos taurus (cattle) | Ki | 0.7800 | 1 | 1 |
| Tubulin beta-2B chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-3 chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-3 chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-4A chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-4A chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-4B chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-4B chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-6 chain | Homo sapiens (human) | IC50 | 23.3117 | 39 | 40 |
| Tubulin beta-6 chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Tubulin beta-8 chain | Homo sapiens (human) | IC50 | 23.3118 | 39 | 40 |
| Tubulin beta-8 chain | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| type-1 angiotensin II receptor | Homo sapiens (human) | IC50 | 18.6390 | 1 | 1 |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0004 | 1 | 1 |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | Ki | 1.7000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 32.5000 | 2 | 2 |
| Tyrosinase | Mus musculus (house mouse) | IC50 | 500.0000 | 1 | 1 |
| Tyrosinase | Mus musculus (house mouse) | Ki | 2,800.0000 | 3 | 3 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 4.2140 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | IC50 | 0.2242 | 21 | 22 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | IC50 | 0.5348 | 22 | 24 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 6,110,215,385.7063 | 13 | 13 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 2.8870 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 18.3333 | 1 | 3 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Ki | 5.1400 | 1 | 2 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 81.4460 | 8 | 10 |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | IC50 | 270.0000 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 2 | Homo sapiens (human) | IC50 | 259.7350 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 6 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Tyrosyl-DNA phosphodiesterase 1 | Homo sapiens (human) | IC50 | 216.5000 | 2 | 2 |
| Tyrosyl-DNA phosphodiesterase 2 | Homo sapiens (human) | IC50 | 0.9700 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 7.6785 | 2 | 2 |
| Ubiquitin-like modifier activating enzyme 2 | Homo sapiens (human) | IC50 | 11.2000 | 2 | 2 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 5.7000 | 2 | 2 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 462.1000 | 1 | 4 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 462.1000 | 1 | 4 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 43.3333 | 1 | 3 |
| Vesicular acetylcholine transporter | Tetronarce californica (Pacific electric ray) | IC50 | 2.6200 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 24.1371 | 6 | 7 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 192.2642 | 7 | 12 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Ki | 1.9000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | Ki | 2.9000 | 1 | 1 |
| XBP1 | Homo sapiens (human) | IC50 | 4.0700 | 1 | 2 |
| Zinc finger protein GLI1 | Homo sapiens (human) | IC50 | 23.7000 | 2 | 3 |
| Zinc finger protein GLI2 | Homo sapiens (human) | IC50 | 0.9100 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | Kd | 0.0170 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | EC50 | 24.5471 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | EC50 | 215.7980 | 3 | 3 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 2 | 2 |
| Adenosine receptor A1 | Homo sapiens (human) | Kd | 12.0000 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | EC50 | 8.0292 | 6 | 6 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | EC50 | 0.0586 | 2 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Kd | 0.6265 | 15 | 15 |
| Adenosine receptor A2b | Homo sapiens (human) | EC50 | 986.2288 | 7 | 7 |
| Adenosine receptor A3 | Homo sapiens (human) | EC50 | 0.6130 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Adrenocorticotropic hormone receptor | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 2.1310 | 3 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Kd | 3.5000 | 4 | 4 |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | EC50 | 0.3300 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | EC50 | 0.3300 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | EC50 | 8.4100 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 10.2000 | 1 | 3 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 7.5109 | 6 | 8 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | EC50 | 0.1480 | 10 | 10 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | Kd | 0.0006 | 1 | 1 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Kd | 8.9125 | 1 | 1 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Aurora kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Bcl-2-like protein 1 | Homo sapiens (human) | EC50 | 0.0233 | 3 | 3 |
| Bcl-2-like protein 1 | Homo sapiens (human) | Kd | 0.0002 | 2 | 2 |
| bcl-2-like protein 11 isoform 1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| Bcl-2-related protein A1 | Homo sapiens (human) | Kd | 1.0000 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 12.0512 | 3 | 5 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Bromodomain testis-specific protein | Homo sapiens (human) | Kd | 0.1786 | 7 | 7 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | Kd | 0.0827 | 12 | 12 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | Kd | 0.0599 | 10 | 10 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | EC50 | 0.1203 | 3 | 3 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | Kd | 0.0912 | 31 | 57 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 20.1040 | 1 | 3 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 20.0810 | 1 | 3 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 21.1990 | 1 | 3 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 1.9953 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | EC50 | 0.1334 | 7 | 7 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 20.5843 | 1 | 3 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 20.0883 | 1 | 3 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Catenin beta-1 | Homo sapiens (human) | Kd | 20.0000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cellular retinoic acid-binding protein 1 | Mus musculus (house mouse) | Kd | 0.0004 | 2 | 2 |
| Cellular retinoic acid-binding protein 2 | Mus musculus (house mouse) | Kd | 0.0020 | 2 | 2 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase | Schizosaccharomyces pombe (fission yeast) | Kd | 1.2000 | 1 | 1 |
| Chain A, BCL-2-RELATED PROTEIN A1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| Chain A, Bromodomain testis-specific protein | Homo sapiens (human) | Kd | 0.1901 | 1 | 1 |
| Chain A, Bromodomain-containing protein 4 | Homo sapiens (human) | Kd | 0.0490 | 1 | 1 |
| Chain A, DODECIN | Halobacterium salinarum R1 | Kd | 1.2680 | 1 | 2 |
| Chain A, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain A, Transthyretin | Homo sapiens (human) | Kd | 0.7500 | 1 | 10 |
| Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase | Schizosaccharomyces pombe (fission yeast) | Kd | 1.2000 | 1 | 1 |
| Chain B, Transthyretin | Homo sapiens (human) | Kd | 0.7500 | 1 | 4 |
| Chain C, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain E, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain H, Immunoglobulin Igg1 Heavy chain | Homo sapiens (human) | Kd | 0.0018 | 1 | 1 |
| Chain L, Immunoglobulin Igg1 Lambda Light Chain | Homo sapiens (human) | Kd | 0.0018 | 1 | 1 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 21.4537 | 1 | 3 |
| CREB-binding protein | Homo sapiens (human) | Kd | 9.6000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 9.3346 | 5 | 7 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Cytochrome P450 1A2 | Homo sapiens (human) | EC50 | 0.0005 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | EC50 | 0.0006 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | EC50 | 0.0012 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | EC50 | 0.0002 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | EC50 | 0.0015 | 1 | 1 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | Kd | 1.9800 | 2 | 2 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 20.2593 | 1 | 3 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| E3 ubiquitin-protein ligase Mdm2 isoform a | Homo sapiens (human) | EC50 | 0.5750 | 3 | 4 |
| Egl nine homolog 1 | Homo sapiens (human) | EC50 | 50.0000 | 1 | 2 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Env polyprotein | Human immunodeficiency virus 1 | EC50 | 100.0000 | 1 | 1 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Estrogen receptor | Rattus norvegicus (Norway rat) | EC50 | 150.0000 | 1 | 2 |
| Estrogen receptor beta | Rattus norvegicus (Norway rat) | EC50 | 150.0000 | 1 | 2 |
| Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 22.5837 | 1 | 4 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| G protein-activated inward rectifier potassium channel 1 | Homo sapiens (human) | EC50 | 100.0000 | 2 | 2 |
| G protein-activated inward rectifier potassium channel 2 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| G protein-activated inward rectifier potassium channel 4 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| G-protein coupled bile acid receptor 1 | Homo sapiens (human) | EC50 | 39.3380 | 4 | 5 |
| G-protein coupled receptor 35 | Homo sapiens (human) | EC50 | 8.0059 | 3 | 7 |
| G-protein coupled receptor 84 | Homo sapiens (human) | EC50 | 18.1833 | 12 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | EC50 | 0.0008 | 1 | 1 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 1.0704 | 2 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 1.0704 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 1.0704 | 2 | 2 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 1.0704 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 1 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 151.9060 | 1 | 2 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Heparanase | Homo sapiens (human) | Kd | 1,000.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | Mus musculus (house mouse) | Kd | 1.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Insulin receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | EC50 | 1.4454 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 0.1892 | 31 | 56 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0077 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Kd | 4.8940 | 2 | 2 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | Kd | 0.0010 | 1 | 1 |
| LacZ protein (plasmid) | Escherichia coli | EC50 | 40.0000 | 1 | 2 |
| large T antigen | Betapolyomavirus macacae | EC50 | 47.9300 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Lymphocyte antigen 96 | Homo sapiens (human) | Kd | 379.0000 | 1 | 1 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 20.0347 | 1 | 3 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Melanocortin receptor 3 | Homo sapiens (human) | EC50 | 0.0039 | 10 | 10 |
| Melanocortin receptor 3 | Mus musculus (house mouse) | EC50 | 0.0769 | 16 | 16 |
| Melanocortin receptor 4 | Homo sapiens (human) | EC50 | 0.0202 | 26 | 26 |
| Melanocortin receptor 4 | Mus musculus (house mouse) | EC50 | 0.1499 | 17 | 17 |
| Melanocortin receptor 5 | Homo sapiens (human) | EC50 | 0.0614 | 8 | 8 |
| Melanocortin receptor 5 | Mus musculus (house mouse) | EC50 | 0.0886 | 17 | 17 |
| Melanocyte-stimulating hormone receptor | Homo sapiens (human) | EC50 | 0.0006 | 13 | 13 |
| Melanocyte-stimulating hormone receptor | Mus musculus (house mouse) | EC50 | 0.0196 | 17 | 17 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 20.0340 | 1 | 3 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 15.0019 | 2 | 4 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 20.6303 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.0077 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Kd | 1.2672 | 4 | 5 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 10.0000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | EC50 | 10.0000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | EC50 | 3.2500 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | EC50 | 10.0000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | EC50 | 10.0000 | 2 | 2 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 20.2073 | 1 | 3 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 13.5027 | 1 | 3 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Nuclear factor erythroid 2-related factor 2 | Homo sapiens (human) | EC50 | 21.0000 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | EC50 | 18.0000 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 4.7250 | 4 | 4 |
| Nuclear receptor subfamily 1 group I member 2 | Rattus norvegicus (Norway rat) | EC50 | 25.1000 | 1 | 1 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | Kd | 6,800.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase | Homo sapiens (human) | Kd | 94.3000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Kd | 0.8000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | EC50 | 17.2500 | 1 | 2 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | EC50 | 23.5750 | 3 | 4 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | EC50 | 52.4000 | 1 | 4 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Phospholipase A2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | Kd | 0.1100 | 1 | 1 |
| POsterior Segregation | Caenorhabditis elegans | EC50 | 60.3740 | 1 | 1 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | EC50 | 486.0000 | 1 | 1 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Procathepsin L | Homo sapiens (human) | EC50 | 10.2000 | 1 | 3 |
| Prolyl hydroxylase EGLN2 | Homo sapiens (human) | EC50 | 50.0000 | 1 | 2 |
| Prolyl hydroxylase EGLN3 | Homo sapiens (human) | EC50 | 50.0000 | 1 | 2 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 20.6903 | 1 | 3 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 29.0810 | 1 | 4 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 20.3583 | 1 | 3 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP3 | Homo sapiens (human) | Kd | 0.7000 | 1 | 1 |
| Protein polybromo-1 | Homo sapiens (human) | Kd | 12.9000 | 1 | 1 |
| Protein S100-B | Homo sapiens (human) | Kd | 1.0000 | 1 | 1 |
| Protein S100-B | Rattus norvegicus (Norway rat) | Kd | 47.0000 | 2 | 2 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 22.7432 | 1 | 4 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 10.3000 | 2 | 4 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 10.2000 | 1 | 3 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 10.3000 | 2 | 4 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 6.1526 | 5 | 8 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 9.0233 | 3 | 6 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Kd | 18.4000 | 3 | 3 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Homo sapiens (human) | Kd | 1.2500 | 1 | 1 |
| Retinoic acid receptor alpha | Homo sapiens (human) | EC50 | 0.1674 | 18 | 18 |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | EC50 | 0.0082 | 3 | 3 |
| Retinoic acid receptor alpha | Homo sapiens (human) | Kd | 0.0102 | 10 | 12 |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | Kd | 0.0150 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | EC50 | 0.0344 | 19 | 19 |
| Retinoic acid receptor beta | Mus musculus (house mouse) | EC50 | 0.0012 | 3 | 3 |
| Retinoic acid receptor beta | Homo sapiens (human) | Kd | 0.0086 | 11 | 13 |
| Retinoic acid receptor beta | Mus musculus (house mouse) | Kd | 0.0130 | 1 | 1 |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | EC50 | 0.0004 | 2 | 2 |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | Kd | 0.0180 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | EC50 | 0.0116 | 16 | 16 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Kd | 0.0103 | 12 | 14 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | EC50 | 0.6141 | 7 | 8 |
| Retinoic acid receptor RXR-alpha | Mus musculus (house mouse) | EC50 | 2.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Kd | 0.0681 | 6 | 8 |
| Retinoic acid receptor RXR-alpha | Mus musculus (house mouse) | Kd | 1.0000 | 1 | 1 |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | EC50 | 1.0496 | 4 | 4 |
| Retinoic acid receptor RXR-beta | Mus musculus (house mouse) | EC50 | 1.2110 | 1 | 1 |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | Kd | 0.0000 | 1 | 1 |
| Retinoic acid receptor RXR-beta | Mus musculus (house mouse) | Kd | 0.6530 | 2 | 2 |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | EC50 | 0.8568 | 4 | 4 |
| Retinoic acid receptor RXR-gamma | Mus musculus (house mouse) | EC50 | 0.4835 | 2 | 2 |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | Kd | 0.1530 | 2 | 2 |
| Retinoic acid receptor RXR-gamma | Mus musculus (house mouse) | Kd | 0.3500 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 20.1607 | 1 | 3 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 20.2520 | 1 | 3 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Kd | 0.0229 | 4 | 4 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Septin-9 | Homo sapiens (human) | Kd | 20.0280 | 1 | 3 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 20.0417 | 1 | 3 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 1,500.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 22.5260 | 1 | 4 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 20.0897 | 1 | 3 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 15.4050 | 1 | 2 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | EC50 | 1.4500 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 31.0000 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | Kd | 64.3000 | 1 | 1 |
| Sphingosine 1-phosphate receptor 2 | Homo sapiens (human) | Kd | 1.9600 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 10.2000 | 1 | 3 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 10.2000 | 1 | 3 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 20.2240 | 1 | 3 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 75.7900 | 2 | 2 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | EC50 | 0.1800 | 1 | 1 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 8.7300 | 3 | 3 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | EC50 | 2.5667 | 3 | 3 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 1.3000 | 2 | 2 |
| Transient receptor potential cation channel subfamily V member 2 | Homo sapiens (human) | EC50 | 1.7000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | EC50 | 1.7000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 3 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 4 | Homo sapiens (human) | EC50 | 5.1000 | 1 | 1 |
| Transmembrane prolyl 4-hydroxylase | Homo sapiens (human) | EC50 | 50.0000 | 1 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 7.9000 | 2 | 4 |
| Transthyretin | Homo sapiens (human) | EC50 | 15.8000 | 1 | 2 |
| Transthyretin | Homo sapiens (human) | Kd | 0.0700 | 1 | 1 |
| Tubulin alpha-1A chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin alpha-1A chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | Kd | 7.5000 | 2 | 2 |
| Tubulin alpha-1B chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin alpha-1B chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin alpha-1C chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin alpha-1C chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin alpha-3C chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin alpha-3C chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin alpha-3E chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin alpha-3E chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin alpha-4A chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin alpha-4A chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta chain | Sus scrofa (pig) | Kd | 7.5000 | 2 | 2 |
| Tubulin beta-1 chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-1 chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-2A chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-2A chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-2B chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-2B chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-3 chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-3 chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-4A chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-4A chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-4B chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-4B chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-6 chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-6 chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin beta-8 chain | Homo sapiens (human) | EC50 | 0.2000 | 1 | 1 |
| Tubulin beta-8 chain | Homo sapiens (human) | Kd | 77.7210 | 3 | 4 |
| Tubulin polymerization-promoting protein | Bos taurus (cattle) | EC50 | 0.7500 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | EC50 | 107.8333 | 1 | 3 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 22.5195 | 1 | 4 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| voltage-dependent T-type calcium channel subunit alpha-1H isoform a | Homo sapiens (human) | EC50 | 5.1500 | 1 | 1 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Zinc finger protein mex-5 | Caenorhabditis elegans | EC50 | 31.0000 | 1 | 1 |