Classes > nordihydroguaiaretic acid
Page last updated: 2024-08-05 12:24:38
nordihydroguaiaretic acid
A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.
ChEBI ID: 7625
Members (1)
| Member | Definition | Role |
|---|
| masoprocol | The meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. | masoprocol |
Research
Studies (1,462)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 435 (29.75) | 18.7374 |
| 1990's | 563 (38.51) | 18.2507 |
| 2000's | 279 (19.08) | 29.6817 |
| 2010's | 146 (9.99) | 24.3611 |
| 2020's | 39 (2.67) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 8 (0.52%) | 5.53% |
| Reviews | 17 (1.11%) | 6.00% |
| Case Studies | 5 (0.33%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,497 (98.04%) | 84.16% |