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hydroxycoumarin

Any coumarin carrying at least one hydroxy substituent.

ChEBI ID: 37912

Members (46)

MemberDefinitionRole
10-hydroxywarfarin4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)-2H-chromen-2-one
2-(5,7-dihydroxy-4-methyl-2-oxo-1-benzopyran-3-yl)acetic acid ethyl ester2-(5,7-dihydroxy-4-methyl-2-oxo-1-benzopyran-3-yl)acetic acid ethyl ester
3-(dimethylamino)benzoic acid (7-hydroxy-2-oxo-1-benzopyran-4-yl)methyl ester3-(dimethylamino)benzoic acid (7-hydroxy-2-oxo-1-benzopyran-4-yl)methyl ester
3-bromo-7-hydroxy-4,8-dimethyl-1-benzopyran-2-one3-bromo-7-hydroxy-4,8-dimethyl-1-benzopyran-2-one
3-hydroxy-1-benzopyran-2-one3-hydroxy-1-benzopyran-2-one
3,8-dibromo-7-hydroxy-4-methylchromen-2-one3,8-dibromo-7-hydroxy-4-methyl-1-benzopyran-2-one
4-hydroxy-3-(1-piperidinylmethyl)-1-benzopyran-2-one4-hydroxy-3-(1-piperidinylmethyl)-1-benzopyran-2-one
4-hydroxycoumarinA hydroxycoumarin that is coumarin in which the hydrogen at position 4 is replaced by a hydroxy group.4-hydroxycoumarin
4-methylesculetinA hydroxycoumarin that is 4-methylcuomarin which is substituted by hydroxy groups at positions 3 and 4. A hyaluronan synthesis inhibitor. It has also been used as a fluorescent sensor to monitor the consumption of a boronic acid in Suzuki coupling reactions; fluorescence is readily detectable by the naked eye using a standard 365 nm UV lamp.6,7-dihydroxy-4-methylcoumarin
4,7-Dihydroxy-2H-1-benzopyran-2-one4,7-Dihydroxy-2H-1-benzopyran-2-one
4'-hydroxywarfarin4-hydroxy-3-[1-(4-hydroxyphenyl)-3-oxobutyl]-2H-chromen-2-one
5,7-dihydroxy-4-methyl-3-(phenylmethyl)-1-benzopyran-2-one5,7-dihydroxy-4-methyl-3-(phenylmethyl)-1-benzopyran-2-one
5,7-dihydroxy-4-methylcoumarin5,7-Dihydroxy-4-methylcoumarin
6-chloro-3-[2-[4-[2,3-dihydro-1,4-benzodioxin-3-yl(oxo)methyl]-1-piperazinyl]-2-oxoethyl]-7-hydroxy-4-methyl-1-benzopyran-2-one6-chloro-3-[2-[4-[2,3-dihydro-1,4-benzodioxin-3-yl(oxo)methyl]-1-piperazinyl]-2-oxoethyl]-7-hydroxy-4-methyl-1-benzopyran-2-one
6-chloro-4-[[(2-fluorophenyl)methyl-methylamino]methyl]-7-hydroxy-1-benzopyran-2-one6-chloro-4-[[(2-fluorophenyl)methyl-methylamino]methyl]-7-hydroxy-1-benzopyran-2-one
6-chloro-7-hydroxy-4-(4-morpholinylmethyl)-1-benzopyran-2-one6-chloro-7-hydroxy-4-(4-morpholinylmethyl)-1-benzopyran-2-one
6-ethyl-7-hydroxy-4-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-1-benzopyran-2-one6-ethyl-7-hydroxy-4-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-1-benzopyran-2-one
7-(diethylamino)-4-hydroxy-1-benzopyran-2-one7-(diethylamino)-4-hydroxy-1-benzopyran-2-one
7-demethylsuberosinA hydroxycoumarin that is 7-hydroxycoumarin which is substituted at position 6 by a 3-methylbut-2-en-1-yl group. A natural product found in Citropsis articulata.7-demethylsuberosin
7-hydroxy-3-(4-methoxyphenyl)-4-methylcoumarinA hydroxycoumarin that is coumarin substituted by a methyl group at position 4, a hydroxy group at position 7 and a p-methoxyphenyl group at position 3 respectively.7-hydroxy-3-(4-methoxyphenyl)-4-methylcoumarin
7-hydroxy-8-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-4-methyl-1-benzopyran-2-one7-hydroxy-8-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-4-methyl-1-benzopyran-2-one
7-hydroxy-8-methyl-4-[[methyl-(phenylmethyl)amino]methyl]-1-benzopyran-2-one7-hydroxy-8-methyl-4-[[methyl-(phenylmethyl)amino]methyl]-1-benzopyran-2-one
7-hydroxycoumarinA hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.umbelliferone
7-hydroxywarfarin7-Hydroxywarfarin
7,8-dihydroxy-4-methylcoumarin7,8-dihydroxy-4-methyl-1-benzopyran-2-one
acenocoumarolA hydroxycoumarin that is warfarin in which the hydrogen at position 4 of the phenyl substituent is replaced by a nitro group.acenocoumarol
coumachlorCoumachlor
coumatetralylCoumatetralyl
daphnetin7,8-dihydroxycoumarin
daphnoretinA member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 6 and a (2-oxo-2H-chromen-7-yl)oxy group at position 3.daphnoretin
dicumarolA hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant.dicoumarol
esculetinA hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.esculetin
esculinA hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.esculin
ethyl biscoumacetateethyl biscoumacetate
fraxetinA hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups.fraxetin
fraxinA beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo.fraxin
hymecromoneA hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4.4-methylumbelliferone
isofraxidinIsofraxidin
isoscopoletinA hydroxycoumarin that is esculetin in which the hydroxy group at position 7 is replaced by a methoxy group. It is the major primary metabolite of scoparone.isoscopoletin
novobiocinA coumarin-derived antibiotic obtained from Streptomyces niveus.novobiocin
osthenolA hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group.osthenol
pacific blue succinimidyl esterAn N-hydroxysuccinimide ester derived from 6,8-difluoro-7-hydroxycoumarin-3-carboxylic acid (pacific blue). A fluorescent dye of excitation wavelength 403 nm and emission wavelength 455 nm.pacific blue succinimidyl ester
phenprocoumonA hydroxycoumarin that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenylpropyl group.phenprocoumon
scopoletinA hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6.scopoletin
urolithin dUrolithin D
warfarinA member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one

Research

Studies (42,764)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199011,350 (26.54)18.7374
1990's4,953 (11.58)18.2507
2000's8,814 (20.61)29.6817
2010's13,787 (32.24)24.3611
2020's3,860 (9.03)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials2,520 (5.28%)5.53%
Reviews4,053 (8.49%)6.00%
Case Studies4,640 (9.72%)4.05%
Observational422 (0.88%)0.25%
Other36,109 (75.63%)84.16%