Roles > glutamine antagonist
Page last updated: 2024-08-05 15:31:34
glutamine antagonist
An antagonist that acts on glutamine receptors.
ChEBI ID: 138931
Members (3)
| Member | Definition | Class |
|---|
| acivicin | An L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl group. A glutamine analogue antimetabolite, it interferes with glutamate metabolism and several glutamate-dependent synthetic enzymes. It is obtained as a fermentation product of Streptomyces sviceus bacteria. | acivicin |
| azaserine | A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species. | azaserine |
| diazooxonorleucine | A non-proteinogenic L-alpha-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes. | 6-diazo-5-oxo-L-norleucine zwitterion; 6-diazo-5-oxo-L-norleucine |
Research
Studies (1,263)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 691 (54.71) | 18.7374 |
| 1990's | 291 (23.04) | 18.2507 |
| 2000's | 134 (10.61) | 29.6817 |
| 2010's | 105 (8.31) | 24.3611 |
| 2020's | 42 (3.33) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 14 (1.01%) | 5.53% |
| Reviews | 50 (3.60%) | 6.00% |
| Case Studies | 2 (0.14%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,321 (95.24%) | 84.16% |
Protein Targets (16)
Potency Measurements