Any organic heterotricyclic compound with a skeleton consisting of an azepine ring fused to an indole.
ChEBI ID: 134691
| Member | Definition | Role |
|---|---|---|
| rucaparib | A member of the class of azepinoindoles that is 1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one carrying additional 4-[(methylamino)methyl]phenyl and fluoro substituents at positions 2 and 8 respectively. It is an inhibitor of poly (ADP-ribose) polymerase and is used (as the camsylate salt) as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. | rucaparib |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (2.16) | 29.6817 |
| 2010's | 119 (51.52) | 24.3611 |
| 2020's | 107 (46.32) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 36 (15.25%) | 5.53% |
| Reviews | 41 (17.37%) | 6.00% |
| Case Studies | 3 (1.27%) | 4.05% |
| Observational | 2 (0.85%) | 0.25% |
| Other | 154 (65.25%) | 84.16% |