| Member | Definition | Role |
|---|
| 1-(2-chloroimidazo(1,2-a)pyridin-3-ylsulfonyl)-3-(4,6-dimethoxypyrimidin-2-yl)urea | | Imazosulfuron |
| 1-(2,7-dimethyl-3-imidazo[1,2-a]pyridinyl)-2-(phenylthio)ethanone | | 1-(2,7-dimethyl-3-imidazo[1,2-a]pyridinyl)-2-(phenylthio)ethanone |
| 1h-imidazo(4,5-b)pyridine | The [4,5-b]-fused isomer of imidazopyridine. | 4-azabenzimidazole |
| 2-(1H-indol-3-yl)-8-methylimidazo[1,2-a]pyridine | | 2-(1H-indol-3-yl)-8-methylimidazo[1,2-a]pyridine |
| 2-(2-furanyl)-N-phenyl-3-imidazo[1,2-a]pyridinamine | | 2-(2-furanyl)-N-phenyl-3-imidazo[1,2-a]pyridinamine |
| 2-(2-imidazo[1,2-a]pyridinylmethylthio)-6-nitro-1H-benzimidazole | | 2-(2-imidazo[1,2-a]pyridinylmethylthio)-6-nitro-1H-benzimidazole |
| 2-(3-imidazo[1,5-a]pyridinylthio)-N-(4-methylphenyl)acetamide | | 2-(3-imidazo[1,5-a]pyridinylthio)-N-(4-methylphenyl)acetamide |
| 2-(4-chlorophenoxy)-N-(2-thiophen-2-yl-3-imidazo[1,2-a]pyridinyl)acetamide | | 2-(4-chlorophenoxy)-N-(2-thiophen-2-yl-3-imidazo[1,2-a]pyridinyl)acetamide |
| 2-[(2-furanylmethylthio)methyl]-5-methylimidazo[1,2-a]pyridine | | 2-[(2-furanylmethylthio)methyl]-5-methylimidazo[1,2-a]pyridine |
| 2-[[(4-chlorophenyl)thio]methyl]-5-methylimidazo[1,2-a]pyridine | | 2-[[(4-chlorophenyl)thio]methyl]-5-methylimidazo[1,2-a]pyridine |
| 2-[[(4-chlorophenyl)thio]methyl]imidazo[1,2-a]pyridine | | 2-[[(4-chlorophenyl)thio]methyl]imidazo[1,2-a]pyridine |
| 2-[[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile | | 2-[[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile |
| 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish. | PhIP |
| 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole | | Glu-P-1 |
| 2-butyl-3-[(3-chlorophenyl)methyl]-5-methyl-6-imidazo[4,5-b]pyridinamine | | 2-butyl-3-[(3-chlorophenyl)methyl]-5-methyl-6-imidazo[4,5-b]pyridinamine |
| 2-ethoxy-3-pyridinecarboxylic acid (6-chloro-2-imidazo[1,2-a]pyridinyl)methyl ester | | 2-ethoxy-3-pyridinecarboxylic acid (6-chloro-2-imidazo[1,2-a]pyridinyl)methyl ester |
| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine | An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP. | N-hydroxy-PhIP |
| 3-[(2-methoxyphenyl)methyl]imidazo[4,5-b]pyridine | | 3-[(2-methoxyphenyl)methyl]imidazo[4,5-b]pyridine |
| 3-[[(1,3-dimethyl-4-pyrazolyl)methyl-methylamino]methyl]-N-methyl-N-(phenylmethyl)-2-imidazo[1,2-a]pyridinecarboxamide | | 3-[[(1,3-dimethyl-4-pyrazolyl)methyl-methylamino]methyl]-N-methyl-N-(phenylmethyl)-2-imidazo[1,2-a]pyridinecarboxamide |
| 3-fluoro-7-methyl-2-imidazo[1,2-a]pyridinecarboxylic acid methyl ester | | 3-fluoro-7-methyl-2-imidazo[1,2-a]pyridinecarboxylic acid methyl ester |
| 3-thiophen-2-ylimidazo[1,5-a]pyridine | | 3-thiophen-2-ylimidazo[1,5-a]pyridine |
| 3,4,5-trimethoxy-N-[(8-methyl-2-imidazo[1,2-a]pyridinyl)methyl]benzamide | | 3,4,5-trimethoxy-N-[(8-methyl-2-imidazo[1,2-a]pyridinyl)methyl]benzamide |
| 4-(2-imidazo[1,2-a]pyridinylmethoxy)benzaldehyde | | 4-(2-imidazo[1,2-a]pyridinylmethoxy)benzaldehyde |
| 6-(2-methyl-3-imidazo[1,2-a]pyridinyl)-1H-pyrimidine-2-thione | | 6-(2-methyl-3-imidazo[1,2-a]pyridinyl)-1H-pyrimidine-2-thione |
| 6-bromo-5-methyl-1,3-dihydroimidazo[4,5-b]pyridine-2-thione | | 6-bromo-5-methyl-1,3-dihydroimidazo[4,5-b]pyridine-2-thione |
| 6-bromo-N-(2-methylphenyl)-2-pyridin-4-yl-3-imidazo[1,2-a]pyridinamine | | 6-bromo-N-(2-methylphenyl)-2-pyridin-4-yl-3-imidazo[1,2-a]pyridinamine |
| 6-bromo-N-tert-butyl-2-methyl-3-imidazo[1,2-a]pyridinamine | | 6-bromo-N-tert-butyl-2-methyl-3-imidazo[1,2-a]pyridinamine |
| 6-chloro-2-[(1H-1,2,4-triazol-5-ylthio)methyl]imidazo[1,2-a]pyridine | | 6-chloro-2-[(1H-1,2,4-triazol-5-ylthio)methyl]imidazo[1,2-a]pyridine |
| 6-chloro-2-[(phenylmethylthio)methyl]imidazo[1,2-a]pyridine | | 6-chloro-2-[(phenylmethylthio)methyl]imidazo[1,2-a]pyridine |
| ageladine a | An imidazopyridine that is 1H-imidazo[4,5-c]pyridin-2-amine substituted by a 4,5-dibromo-1H-pyrrol-2-yl group at position 4. It is an alkaloid isolated from a marine sponge Agelas nakamurai and acts as an inhibitor of the matrix metalloproteinases, the key enzymes involved in tumour growth, migration, angiogenesis, invasion and metastasis. | ageladine A |
| fadrozole | | 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile |
| fluazaindolizine | A member of the class of imidazopyridines that is the amide formed from the formal condensation of the carboxy group of 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid with the sulfonamide nitrogen of 2-chloro-5-methoxybenzene-1-sulfonamide. | fluazaindolizine |
| fluromidine | | Fluoromidine |
| GDC-0623 | A member of the class of imidazopyridines that is imidazo[1,5-a]pyridine substituted by (2-fluoro-4-iodophenyl)amino and (2-hydroxyethoxy)aminoacyl groups at positions 5 and 6. It is a potent ATP non-competitive inhibitor of MEK1 (Ki = 0.13nM) and also has efficacy against both mutant BRAF and mutant KRAS. It is in clinical development for treatment of patients with locally advanced or metastatic solid tumors. | GDC-0623 |
| glu-p-2 | | Glu-P-2 |
| gsk690693 | A member of the class of imidazopyridines that is 4-(1-ethylimidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol carrying additional 2-(4-amino-1,2,5-oxadiazol-3-yl and [(3S)-piperidin-3-yl]methoxy substituents at positions 4 and 7 respectively. | GSK690693 |
| ly2090314 | A member of the class of diazepinoindoles that is 1,2,3,4-tetrahydro[1,4]diazepino[6,7,1-hi]indole substituted by piperidin-1-ylcarbonyl, 4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl and fluoro groups at position 2, 7 and 9, respectively. It is a potent ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3alpha and GSK-3beta. The drug is in clinical development for the treatment of advanced/metastatic cancer. | LY-2090314 |
| miroprofen | A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and platelet aggregation inhibition properties. | miroprofen |
| N-(1,3-benzodioxol-5-yl)-6-chloro-2-(2-pyridinyl)-3-imidazo[1,2-a]pyridinamine | | N-(1,3-benzodioxol-5-yl)-6-chloro-2-(2-pyridinyl)-3-imidazo[1,2-a]pyridinamine |
| N-(2-furanylmethyl)-3-[3-[(4-methoxyphenyl)methyl]-2-imidazo[4,5-b]pyridinyl]propanamide | | N-(2-furanylmethyl)-3-[3-[(4-methoxyphenyl)methyl]-2-imidazo[4,5-b]pyridinyl]propanamide |
| N-(2-furanylmethyl)-4-(2-methyl-3-imidazo[1,2-a]pyridinyl)-2-thiazolamine | | N-(2-furanylmethyl)-4-(2-methyl-3-imidazo[1,2-a]pyridinyl)-2-thiazolamine |
| N-(2,5-diethoxyphenyl)-2-[(3-methyl-2-imidazo[4,5-b]pyridinyl)thio]acetamide | | N-(2,5-diethoxyphenyl)-2-[(3-methyl-2-imidazo[4,5-b]pyridinyl)thio]acetamide |
| N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[3-(phenylmethyl)-2-imidazo[4,5-b]pyridinyl]thio]acetamide | | N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[3-(phenylmethyl)-2-imidazo[4,5-b]pyridinyl]thio]acetamide |
| N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[(3-methyl-2-imidazo[4,5-b]pyridinyl)thio]acetamide | | N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[(3-methyl-2-imidazo[4,5-b]pyridinyl)thio]acetamide |
| pd 123319 | An imidazopyridine consisting of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine having 4-(dimethylamino)-3-methylbenzyl, diphenylacetyl and carboxy and groups at positions 1, 5 and 6 respectively | PD123319 |
| pentosidine | An imidazopyridine having norleucine and ornithine residues attached via their side-chains at the 4- and 2-positions respectively. | pentosidine |
| sch 28080 | | 2-(2-methyl-8-phenylmethoxy-3-imidazo[1,2-a]pyridinyl)acetonitrile |
| sulmazole | An imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardiotonic agent. | sulmazole |
| tenatoprazole | | 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine |
| zolpidem | An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position. | zolpidem |