An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.
ChEBI ID: 26271
| Member | Definition | Role |
|---|---|---|
| D-proline | The D-enantiomer of proline. | D-proline zwitterion; D-proline |
| proline | Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. | L-proline zwitterion; L-proline |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 7,760 (36.30) | 18.7374 |
| 1990's | 2,824 (13.21) | 18.2507 |
| 2000's | 4,400 (20.58) | 29.6817 |
| 2010's | 4,814 (22.52) | 24.3611 |
| 2020's | 1,577 (7.38) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 520 (2.35%) | 5.53% |
| Reviews | 901 (4.07%) | 6.00% |
| Case Studies | 647 (2.92%) | 4.05% |
| Observational | 59 (0.27%) | 0.25% |
| Other | 20,012 (90.39%) | 84.16% |