Any member of a group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids that exhibit biological activity against vitamin A deficiency. Vitamin A is involved in immune function, vision, reproduction, and cellular communication.
ChEBI ID: 12777
| Member | Definition | Role |
|---|---|---|
| 3,4-didehydroretinoic acid | A retinoid obtained by 3,4-desaturation of beta-ionone ring of all-trans-retinoic acid | all-trans-3,4-didehydroretinoic acid |
| retinaldehyde | A retinal in which all four exocyclic double bonds have E- (trans-) geometry. | all-trans-retinal |
| retinol | A retinol in which all four exocyclic double bonds have E- (trans-) geometry. | all-trans-retinol |
| tretinoin | A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. | all-trans-retinoic acid |
| vitamin a2 | A retinoid derived from 3,4-desaturation of the beta-ionone ring of all-trans-retinol. | all-trans-3,4-didehydroretinol |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 14,760 (31.72) | 18.7374 |
| 1990's | 10,244 (22.01) | 18.2507 |
| 2000's | 9,865 (21.20) | 29.6817 |
| 2010's | 8,860 (19.04) | 24.3611 |
| 2020's | 2,810 (6.04) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 2,676 (5.17%) | 5.53% |
| Reviews | 4,451 (8.60%) | 6.00% |
| Case Studies | 1,949 (3.77%) | 4.05% |
| Observational | 54 (0.10%) | 0.25% |
| Other | 42,609 (82.35%) | 84.16% |