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1,2-benzisothiazole

A benzothiazole consisting of a benzene ring fused to an isothiazole.

ChEBI ID: 55505

Members (4)

MemberDefinitionRole
lurasidoneAn N-arylpiperazine that is (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-(piperazin-1-ylmethyl)cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione in which position N4 of the piperazine ring is substituted by a 1,2-benzothiazol-3-yl group. Lurasidone is used (generally as the hydrochloride salt) as an atypical antipsychotic for the treatment of schizophrenia.lurasidone
oryzemateA member of the class of 1,2-benzothiazoles that is 1,2-benzothiazole 1,1-dioxide substituted at position 3 by an allyloxy group. A fungicide used to control rice blast.probenazole
saccharinA 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.saccharin
ziprasidoneA piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.ziprasidone

Research

Studies (4,021)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,184 (29.45)18.7374
1990's475 (11.81)18.2507
2000's1,061 (26.39)29.6817
2010's1,064 (26.46)24.3611
2020's237 (5.89)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials330 (7.71%)5.53%
Reviews283 (6.61%)6.00%
Case Studies211 (4.93%)4.05%
Observational4 (0.09%)0.25%
Other3,454 (80.66%)84.16%