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Psoriasis

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Synonyms(1)

Synonym
Psoriasis

Research Excerpts

Overview

ExcerptReference
"The onset of psoriasis is observed before the age of 10 years in 15% of all patients."( Beylot, C; Bioulac, P; Doutre, MS; Pringuet, R; Puissant, A; Saurat, JH, 1979)
"Psoriasis is a disease characterized by benign but unrestricted epithelial growth."( Voorhees, JJ, 1977)
"Although psoriasis is a genetically transferred disease, little is known of the factors causing spontaneous eruption of a proliferative lesion in apparently normal epidermis."( Plummer, NA, 1979)
"A case of EAC type psoriasis is reported."( Rajka, G; Thune, PO, 1979)
"Psoriasis is a chronic, relapsing dermatosis characterised by scaling, erythema, and less commonly pustulation."( Comaish, JS; Hodge, L, 1977)
"We conclude that psoriasis is a genetically determined disorder that may, to a limited extent, be modified by environmental influences."( Brandrup, F; Eriksen, B; Hauge, M; Henningsen, K, 1978)
"Psoriasis is a prototype of several common, glucocorticoid responsive, inflammatory proliferative skin diseases."( Anderson, TF; Duell, EA; Hamberg, M; Hammarström, S; Stawiski, MA; Voorhees, JJ, 1977)
"The chemotherapy of psoriasis is reviewed in 246 patients from 1964 to 1974 treated with methotrexate, 92 patients from 1971 to 1974 with hydroxyurea, and 36 patients from 1972 to 1974 with azaribine."( Moschella, SL, 1976)
"A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0."( Frost, P; Gomez, EC, 1976)
"Psoriasis is a autosomal hereditary disease of the skin, which has been treated with a great number of possibly carcinogenic substances."( Bohnert, E; Jung, EG, 1975)
"Psoriasis is a common disorder characterized by marked increases in keratinocyte proliferation, abnormal patterns of keratinocyte differentiation, prominent alterations in dermal capillary vasculature and the presence of dermal and epidermal T cells, monocytes/macrophages and neutrophils."( Das, UN; Koratkar, R; Madhavi, N; Padma, M; Ramesh, G; Sagar, PS; Sravankumar, G; Suryaprabha, P; Vijaykumar, K, 1992)
"Psoriasis is suggested to be an autoimmune disease and in severe, uncontrollable psoriasis CsA and Mx are of value in reducing disease activity."( Hammer, JH; Nielsen, HJ, 1992)
"Psoriasis is a chronic inflammatory skin disease of unknown etiology."( Bjerke, JR, 1992)
"CsA therapy for psoriasis is hampered by side-effects."( Korstanje, MJ, 1992)
"Psoriasis is a humorally controlled systemic disease."( Holzmann, H; Hör, G; Maul, FD; Werner, RJ, 1992)
"Psoriasis is a disorder of abnormal keratinocyte proliferation mediated by T lymphocytes."( Fry, L, 1992)
"Psoriasis is a common skin disease in which retinoids have beneficial effects."( Donnadieu, M; Evain-Brion, D; Gerbaud, P; Gu, XF; Raynaud, F, 1991)
"Psoriasis is a genetically determined chronic disease of the skin, and an accelerated proliferation of epidermal keratinocytes is one of the pathophysiological characteristics of psoriatic lesion."( Ikeda, N; Kitano, Y; Okano, M, 1991)
"Psoriasis is an inflammatory disease of the skin associated with increased epidermal proliferation."( Maibach, HI; Tung, JP, 1990)
"Since psoriasis is thought to involve hyperproliferative expansion of the basal compartment from one to about three cell layers in thickness, the samples were screened with antibodies to intermediate filament determinants associated with basal cells, suprabasal cells and hyperproliferating keratinocyte-derived cell lines, respectively."( Lane, EB; Leigh, IM; Pulford, KA; Ramaekers, FC, 1985)
"BKH in active psoriasis are associated with electron-lucent areas suggestive of proteolytic enzyme release."( Chase, DG; Heng, MC; Kloss, SG; Kuehn, CS, 1986)
"Psoriasis is a common papulosquamous skin disease."( Gottlieb, AB; Granelli-Piperno, A; Grossman, RM; Krueger, J; Kupper, TS; May, LT; Murphy, DP; Sehgal, PB; Yourish, D, 1989)
"Psoriasis is associated with abnormally exaggerated epidermal cellular turnover."( Morimoto, S; Yoshikawa, K, 1989)
"Psoriasis is a hyperproliferative epidermal disease in which EGF receptor expression is altered and phospholipase C activity is increased."( Elder, JT; Fisher, GJ; Lee, CS; Pike, MC; Voorhees, JJ, 1989)
"Psoriasis is difficult to manage in general practice, mainly because the standard treatments produce side effects, or are ineffective in both the short and long term."( Harrington, CI, 1989)
"Psoriasis is a hereditary disease primarily affecting the skin and characterized by an abnormally high proliferation rate of the epidermal cells."( Späder, M; Unteregger, G, 1989)
"Because psoriasis is a very complex disease and its activity is often unpredictable, clinical studies on adverse drug effects on psoriasis have been difficult to conduct."( Abel, EA; DiCicco, LM; Farber, EM; Fraki, JE; Orenberg, EK, 1986)
"Severe psoriasis is commonly associated with depression and may be its cause."( Baker, H; Barth, JH, 1986)
"As psoriasis is a proliferative skin disease, the activity of this enzyme was assayed in 35 psoriatic Danes and in 25 long-term local hotel workers, as well as in 34 volunteers drinking low-selenium water."( Even-Paz, Z; Livshitz, T; Robberecht, H; Rubinstein, N; Shani, J; Van Grieken, R, 1985)
"Psoriasis is a common papulosquamous skin disease which frequently presents a therapeutic challenge to physicians."( Lowe, NJ, 1983)
"Psoriasis is a disease where changes in epidermal proliferation may be an important factor."( Ashton, R; Connor, MJ; Lowe, NJ; Wortzman, M, 1984)
"Because psoriasis is a disease of unknown etiology, all treatments are based on empirical experience and diverse scientific theories."( Abel, EA; Charuworn, A; Farber, EM, 1983)
"The disease of psoriasis is examined as to its incidence, etiology, clinical manifestations, and possible complications."( Bryant, BG, 1980)
"Psoriasis is a disease of major importance, the cause of which is unknown and treatment often difficult."( Cram, DL, 1981)
"Psoriasis is currently considered an incurable skin disorder whose etiology is unknown."( Dellon, AL, 1982)
"Psoriasis is marked by loss of glycoalyx."( Kunze, D; Meffert, H; Metz, D; Rüstow, B, 1981)
"Although psoriasis is characterized by the accumulation of activated proliferating lymphoid cells in the psoriatic skin lesion, it is not known whether these cells are activated and proliferating before entry into the psoriatic plaque."( Alzona, CP; Edwards, S; Herrod, R; Jeffes, EW; Lee, GC; Linden, KG; McCullough, JL; Sabahi, M; Said, S; Soundararajan, D, 1995)
"Psoriasis is a common inherited skin disease that is characterized by hyperproliferation of epidermal keratinocytes and excessive dermal angiogenesis."( Dixit, VM; Mitra, RS; Nickoloff, BJ; Polverini, PJ; Varani, J, 1994)
"Psoriasis is characterized by alterations in both the epidermis and dermis of the skin."( Battat, L; Gilleaudeau, P; Gottlieb, AB; Heftler, N; Hodak, E; Krueger, JG; Nabeya, R; Vallat, VP; Wolfe, J, 1994)
"Treatment of psoriasis is rapidly changing with improved understanding of the pathogenesis of the disease."( Lewis, HM, 1994)
"Psoriasis is characterized by immune activation and increased epidermal proliferation."( Gilleaudeau, P; Gottlieb, AB; Gottlieb, SL; Heftler, NS; Johnson, R; Krueger, JG; Vallat, VP; Wolfe, J, 1995)
"The pathogenesis of psoriasis is not fully understood, but two mechanisms seem important, i."( Panizzon, R, 1995)
"Psoriasis is a benign but hyperproliferative skin disease."( Bhardwaj, R; Buchegger, F; Goerdt, S; Grunert, F; Hagemeier, HH; Sorg, C; von Kleist, S, 1993)
"Scalp psoriasis is associated with hair loss and an increased telogen/anagen ratio."( Kuijpers, AL; van Baar, HM; van de Kerkhof, PC; van Gasselt, MW, 1995)
"Psoriasis is a skin disorder characterized by hyperproliferation of epidermal keratinocytes."( Chen, ML; Chen, TC; Heinrich, G; Holick, MF; Perez, A; Sanan, DK, 1996)
"Psoriasis is characterized by hyperproliferation and impared differentiation of epidermal keratinocytes (KCs)."( Fogh, K; Jøhnke, H; Kragballe, K; Sølvsten, H, 1996)
"Psoriasis is a heterogeneous disorder not only in regard to its variability in clinical expression and age at onset, but also in the degree to which genetic and immunological factors such as T cells and cytokines contribute."( Christophers, E, 1996)
"Psoriasis is an inherited condition that may require specific environmental factors to become activated; immunological factors are clearly important in pathogenesis."( Weller, PA, 1996)
"Psoriasis is a chronic skin disease characterized by epidermal hyperproliferation, disturbed differentiation, and inflammation."( Boezeman, JB; de Jongh, GJ; Schalkwijk, J; van Erp, PE; van Ruissen, F, 1996)
"Psoriasis is associated with production of gamma interferon (IFN gamma), which induces the expression of keratin K17 by activating transcription factor STAT1."( Blumenberg, M; Freedberg, IM; Komine, M, 1996)
"psoriasis) are discussed."( Boezeman, JB; Brons, PP; van Erp, PE, 1996)
"Psoriasis is a T-cell-mediated inflammatory skin disease which can be treated successfully with immunosuppressive drugs."( Bos, JD; De Rie, MA; Out, TA; Van Lier, RA; Witkamp, L; Zonneveld, IM, 1996)
"Psoriasis is characterized by immune activation, increased proliferation and abnormal differentiation of keratinocytes."( Gilleaudeau, P; Gottlieb, AB; Gottlieb, S; Heftler, N; Kamber, M; Krueger, JG; Lu, I; McLane, JA, 1996)
"Psoriasis is a common chronic skin disease mediated by cellular immune mechanisms and characterized by an intense neutrophil cell infiltrate and proliferative activation of epidermal keratinocytes."( Bruch-Gerharz, D; Fehsel, K; Kolb-Bachofen, V; Michel, G; Ruzicka, T; Suschek, C, 1996)
"Psoriasis is characterized by abnormal cell proliferation, inflammation and increased biosynthesis of various cytokines."( Cohen, S; Eitan, A; Gilhar, A; Grossman, N; Kahanovicz, S; Reuveni, H, 1996)
"Psoriasis is a chronic inflammatory disorder characterized by epidermal hyperproliferation."( Hatta, N; Hirone, T; Kawara, S; Takata, M; Takehara, K, 1997)
"PUVA treatment of psoriasis is usually given with broad-band fluorescent UVA lamps."( de Berker, DA; Diffey, BL; Farr, PM; Matthews, JN; Sakuntabhai, A, 1997)
"Psoriasis is a common condition which, at times, can be difficult to treat."( Crutchfield, CE; Lewis, EJ; Zelickson, BD, 1997)
"Pustular psoriasis is a rare form of psoriasis that can be divided into generalized and localized forms."( Tay, YK; Tham, SN, 1997)
"Psoriasis is a T-cell mediated inflammatory skin disease which has been associated with group A, beta-haemolytic streptococcal infections."( Good, MF; Jonsdottir, I; Sigmundsdottir, H; Sigurgeirsson, B; Troye-Blomberg, M; Valdimarsson, H, 1997)
"Psoriasis is a chronic immune-mediated disease that is characterized by the hyperproliferation and abnormal differentiation of keratinocytes and by inflammation."( Asano, AT; Chandraratna, RA; Duvic, M; Nagpal, S, 1997)
"Psoriasis is a skin disease that appears to result from a dysfunction in the normal mechanism(s) that regulates wound healing."( Morhenn, VB, 1997)
"Pustular psoriasis is a rare skin disease that is observed in about 1% of all patients with psoriasis."( Amano, T; Nakayama, Y; Seki, K, 1997)
"Psoriasis is a chronic genetic disease characterized by hyperproliferation and inflammation of the epidermis and dermis."( McClelland, PB, 1997)
"Psoriasis is such one disease holding great interest for dermatology owing to its high rate of incidence and complexity of treatment."( Biagini, G; Carraro, S; Cataldi, I; Giardino, R; Lucarini, G; Mattei, G; Ricotti, G; Solmi, R; Tosi, L; Tucci, MG, 1997)
"Psoriasis is a chronic T-cell-mediated inflammatory skin disease which can be treated with topical medication, phototherapy or systemic medication."( Bos, JD; de Rie, MA; Out, TA, 1998)
"Psoriasis is probably no more common in HIV infection than in the general population; however, it may appear for the first time or pre-existing psoriasis may worsen and be difficult to treat in HIV disease."( Bunce, M; Bunker, CB; Easterbrook, PJ; Gotch, FM; Mallon, E; Newson, R; Young, D, 1998)
"Psoriasis is associated with upregulation or downregulation of several of these markers."( Asano, AT; Duvic, M; Hager, C; Mays, S, 1998)
"Psoriasis is common, chronic and currently incurable."( Griffiths, CE, 1998)
"Pruritus in psoriasis is coupled to disease severity."( Bräutigam, M; Hultsch, T; Lotz, J; Schopf, RE, 1998)
"Psoriasis is a common dermatosis, affecting from 1 to 3 percent of the population."( Federman, DG; Froelich, CW; Kirsner, RS, 1999)
"Psoriasis is a chronic inflammatory skin disease."( Nave, B; Ott, R; Severin, E; Ständer, M; Traupe, H, 1999)
"Psoriasis is a T cell-mediated inflammatory skin disease that has been associated with infections by group A beta-haemolytic streptococci."( Good, MF; Gudmundsdottir, AS; Jonsdottir, I; Sigmundsdottir, H; Sigurgeirsson, B; Valdimarsson, H, 1999)
"Because psoriasis is not cured by PUVA, patients receive many treatments over their lifetime and develop a significant risk for the development of skin cancers (primarily squamous cell carcinomas)."( Gasparro, FP; Peritz, AE, 1999)
"Psoriasis is a T-cell mediated autoimmune disease."( Avgerinou, G; Barkis, J; Degiannis, D; Demetriou, Z; Economidou, J; Katsambas, A; Psarra, K; Vareltzidis, A, 1999)
"Psoriasis is characterized by hyperproliferation of keratinocytes associated with an inflammatory infiltrate in the epidermis."( Ben-Bassat, H; Chaouat, M; Chen, H; Gazit, A; Harzstark, Z; Klein, BY; Levitzki, A; Levitzki, R; McCollough, J; McMahon, J; Narog, B; Powell, TJ; Shawver, L; Shenoy, N; Tang, C, 1999)
"Psoriasis is a common and persistent disease characterized chiefly by marked epidermal and endothelial cell proliferation and inflammation."( Auerbach, R; Burack, LH; Cardinale, I; Coven, TR; Gilleaudeau, P; Krueger, JG; Murphy, FP, 1999)
"Psoriasis is a chronic inflammatory skin disease, and besides inflammation, disturbed differentiation and hyperproliferation are its hallmarks."( Goossen, JW; Mommers, JM; van De Kerkhof, PC; van Erp, PE, 2000)
"Pustular psoriasis is a rare but serious form of psoriasis."( Barker, JN; Wakelin, SH; Whittam, LR, 2000)
"Psoriasis is often treated with agents that activate nuclear hormone receptors for glucocorticoids, retinoids, and vitamin D."( Benson, SC; Chi, Y; Ellis, CN; Fisher, GJ; Kurtz, TW; Pershadsingh, HA; Varani, J; Zeigler, ME, 2000)
"Treatment of psoriasis is rapidly changing, and there have been dramatic additions such as topical vitamin D analogs and a topical retinoid to the therapeutic armamentarium in recent years."( Müller, K, 2000)
"Psoriasis is a heterogeneous disease in which several reports suggest the presence of a susceptibility gene in or in the proximity of the human leukocyte antigen complex in chromosome 6p."( Enerbäck, C; Enlund, F; Inerot, A; Martinsson, T; Samuelsson, L; Swanbeck, G; Wahlström, J, 2000)
"Psoriasis is still a relatively poorly understood inflammatory dermatosis that is resistant to many therapies."( Danby, FW; Rowlands, CG, 2000)
"Nail psoriasis is often difficult to cure, but may respond to a range of different approaches used alone or together."( de Berker, D, 2000)
"Psoriasis is one of the most common skin disorders affecting approximately 2% of the population; the disease is recurrent and can be very debilitating."( Chandraratna, RA; DiSepio, D, 2000)
"Given that psoriasis is a chronic recurrent disease for most patients, longer trials are needed to determine whether the addition of topical calcipotriene to systemic therapy improves the risk-benefit ratio by reducing the long-term risk of toxic effects."( Ashcroft, DM; Griffiths, CE; Li Wan Po, A; Williams, HC, 2000)
"Psoriasis is a chronic inflammatory skin disease that rarely involves the oral cavity."( Brice, DM; Danesh-Meyer, MJ, 2000)
"Psoriasis is a chronic inflammatory skin disease in which epidermal hyperplasia results from the release of cytokines by infiltrating type 1 T cells."( Blaschke, V; Garbe, C; Lippert, U; Maurer, C; Middel, P; Neumann, C; Reich, K; Westphal, G, 2001)
"Psoriasis is currently considered to be an inflammatory disease of the skin mediated by T-lymphocytes."( Svecova, D, 2000)
"Psoriasis is a complex disorder that negatively impacts quality of life."( Feldman, S, 2000)
"Psoriasis is a chronic inflammatory skin disease in which epidermal proliferation is closely associated with excessive microvascular expansion within the papillary dermis."( Fleischmajer, R; Kuroda, K; Lebwohl, M; Sapadin, A; Shoji, T, 2001)
"Psoriasis is a disease marked by keratinocyte hyperproliferation, neutrophil and lymphocyte infiltration, and aberrant epidermal and dermal expression of cytokines."( Hunter, JA; McKenzie, RC; Szepietowski, J; Walker, C, 2001)
"Psoriasis is a hyperproliferative skin disorder estimated to be present in 1-3% of most populations."( Karlsen, G; Leigh, IM; Navsaria, H; Raman, A; Sampson, JH, 2001)
"Scalp psoriasis is a frequent expression of the common skin disease psoriasis, and scaling and itching are the two major complaints."( van de Kerkhof, PC; van der Vleuten, CJ, 2001)
"Psoriasis is a chronic skin disease characterized by epidermal hyperproliferation, which may be regulated by several mechanisms including apoptosis."( Fukuya, Y; Higaki, M; Higaki, Y; Kawashima, M, 2002)
"Psoriasis is recognized as the most common T cell-mediated inflammatory disease in humans."( Dorner, AJ; Gilleaudeau, P; Kikuchi, T; Krueger, JG; Oestreicher, JL; Schwertschlag, U; Surette, J; Trepicchio, WL; Walters, IB, 2001)
"Psoriasis is characterized by defects in the normal cycle of epidermal development that lead to epidermal hyperproliferation, altered maturation of skin cells, vascular changes and inflammation."( Ari, Z; Durkan, K; Gündüz, K; Onur, E; Tanülkü, S; Uyanik, BS, 2002)
"Psoriasis is a common skin disease, with a clinical appearance of red, scaly lesions, known as plaques."( Savill, NJ; Sherratt, JA; Weller, R, 2002)
"Psoriasis is an inflammatory skin disorder with hyperproliferation of keratinocytes, that can be the result of insufficient inhibitory effect of transforming growth factors-beta (TGF-beta)."( Chodynicka, B; Flisiak, I; Flisiak, R; Porebski, P, 2002)
"Psoriasis is a chronic, debilitating skin condition that affects millions of people and is attributed to both genetic and environmental factors."( Gordon, KB; McClure, SL; Valentine, J, 2002)
"Mild to moderate psoriasis is a disease that can often be treated with topical medications."( Bruner, CR; Feldman, SR; Fleischer, AB; Ventrapragada, M, 2003)
"Psoriasis is one of the diseases associated with increased atherothrombosis."( Alver, A; Cimşit, G; Orem, A; Uydu, HA; Vanizor Kural, B; Yandi, YE, 2003)
"Psoriasis is an immunogenetic disorder."( Arrese, JE; Hermanns-Lê, T; Piérard, GE; Piérard-Franchimont, C; Quatresooz, P; Uhoda, I, 2003)
"Psoriasis is a disease characterized by inflammation and increased population of hyperproliferative keratinocytes."( Chen, J; Guo, Z; Li, Q; Tang, L; Yan, M; Yu, Y, 2003)
"Acute pustular psoriasis is characterized by fiery-red erythema followed by formation of pustules."( Welsch, MJ, 2003)
"Psoriasis is a chronic inflammatory T-cell-mediated immune dermatosis, characterized by the cutaneous expression of adhesion molecules belonging to the beta1 and beta2 integrin subfamilies, such as intracellular adhesion molecule (ICAM)-1, ICAM-3, lymphocyte function associated antigen (LFA)-1, vascular cell adhesion molecule (VCAM)-1 and endothelial adhesion molecule (ELAM)-1."( Caproni, M; Fabbri, P; Floriani, I; Pestelli, E, 2003)
"Psoriasis is an autoimmune disease affecting 2-4% of the Caucasian population."( Ghoreschi, K; Mrowietz, U; Röcken, M, 2003)
"Psoriasis is an inflammatory disorder characterized by a T helper type 1 cell cytokine pattern."( Namazi, MR, 2003)
"Psoriasis is a chronic inflammatory skin disease."( Joshi, R; Langguth, P; Merkle, HP; Werdenberg, D; Wolffram, S, 2003)
"Psoriasis is a disease characterized by an abnormal pattern of keratinocyte growth and differentiation."( Agozzino, M; Baroni, A; Donnarumma, G; Paoletti, I; Ruocco, E; Tufano, MA, 2004)
"Psoriasis is a common, chronic inflammatory skin disease with unknown etiology."( Api, H; Atik, U; Baz, K; Cimen, MY; Eskandari, G; Ikizoglu, G; Kokturk, A; Yazici, AC, 2003)
"Psoriasis is a common skin disease characterized by hyperplastic regenerative epidermal growth and infiltration of immunocytes."( Chiba, H; Imai, Y; Kawasaki, S; Michibata, H; Mitsui, H; Okubo, K; Seishima, M; Torii, H; Wakimoto, K, 2004)
"Psoriasis is a common, chronic, cell-mediated, inflammatory skin disease."( Carboni, I; Chimenti, S; De Felice, C; De Simoni, I; Soda, R, 2004)
"Psoriasis is a common skin disorder associated with significant morbidity."( Elias, AN, 2004)
"Psoriasis is a multifactorial, chronically relapsing, inflammatory skin disease occurring in 1-3% of the world's population."( Aldebani, S; Alhaddar, J; Benghazil, M; Duweb, G; Elzorghany, A, 2003)
"Psoriasis is regarded as a Th1-cell type disease."( Dziankowska-Bartkowiak, B; Sysa-Jedrzejowska, A; Wyczółkowska, J; Zalewska, A, 2004)
"Psoriasis is a common chronic cutaneous disease affecting 1-3% of general population."( Baran, E; Nockowski, P; Szepietowski, JC; Ziarkiewicz, M, 2004)
"Since psoriasis is exacerbated in HIV infection possibly due to the increased staphylococcal colonization, and psoriatic keratinocytes could aggravate HIV infection through production of TNF-alpha, it could be reasoned that in HIV-positive psoriatics a strong vicious cycle is present between the degree of immune deficiency and the staphylococcal colonization, explaining the poor prognosis of both AIDS and psoriasis in these patients."( Namazi, MR, 2004)
"Psoriasis is a chronic condition that shows variability in phenotype and severity."( Ho, VC, 2004)
"Psoriasis is uncommonly seen in Africans, probably partly due to genetic factors."( Namazi, MR, 2004)
"Psoriasis is recognized as a chronic inflammatory disease characterized by epidermal hyperproliferation."( Chiba, H; Imai, Y; Kawasaki, S; Michibata, H; Mitsui, H; Okubo, K; Seishima, M; Torii, H; Wakimoto, K, 2004)
"Psoriasis is recognized as the most prevalent T-cell-mediated inflammatory disease in humans, with predominantly activated T-helper (Th) 1 cell effectors."( Barba-Gómez, JF; Guevara-Gutiérrez, E; Ornelas-Aguirre, JM; Rodríguez-Castellanos, MA; Salazar-Páramo, M; Tlacuilo-Parra, JA, 2004)
"Psoriasis is a complex disease with a spectrum of clinical manifestations."( van de Kerkhof, PC; Vissers, WH, 2004)
"Psoriasis is a chronic inflammatory skin disorder characterized by accumulation of Th1-type T cells and neutrophils, regenerative keratinocyte proliferation and differentiation, and enhanced epidermal production of antimicrobial peptides."( Beckmann, I; Hallermann, C; Mössner, R; Neumann, C; Reich, K, 2004)
"Psoriasis is a chronic inflammatory skin disease that is known to have a strong genetic predisposition."( Holm, SJ; Mallbris, L; O'Brien, KP; Sánchez, F; Ståhle, M, 2004)
"Psoriasis is a common condition, affecting 1."( Cooper, AJ; Ilchef, R; Russo, PA, 2004)
"Psoriasis is a common benign skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes."( Dam, TN; Iversen, L; Johansen, C; Kragballe, K; Rasmussen, M, 2004)
"Psoriasis is a common disease and may have a significant impact on patients' quality of life (QoL)."( van de Kerkhof, PC, 2004)
"Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use."( Litjens, NH; Mattie, H; Nibbering, PH; Thio, HB; van Dissel, JT; van Gulpen, C; van Strijen, E, 2004)
"Psoriasis is a common, chronic dermatological disorder."( Kapuścińska, R; Niczyporuk, W; Wysocka, J; Zelazowska, B, 2004)
"Psoriasis is a chronic skin disorder that affects approximately 2% of the US and European population."( Saini, R; Tutrone, WD; Weinberg, JM, 2005)
"Psoriasis is believed to be a T cell-mediated autoimmune disease, but also exhibits autoantibody production."( Kawara, S; Matsushita, Y; Sato, S; Shimada, Y; Takehara, K, 2005)
"Psoriasis is a clinical conundrum that affects an estimated 1-3% of the world's population."( Namazi, MR, 2005)
"Psoriasis is a common, persistent skin disorder characterized by recurrent erythematous lesions thought to arise as a result of inflammatory cell infiltration and activation of keratinocyte proliferation."( Arbiser, J; Babichev, YO; Chang, W; Chen, S; Cruz, M; Dagnino, L; Dumont, DJ; Haninec, A; Jones, J; Jones, N; Jothy, S; Kerbel, RS; Klement, G; Master, Z; Sturk, C; Tran, J; Van Slyke, P; Voskas, D; Ward, N, 2005)
"Psoriasis is a T cell-mediated inflammatory skin disease."( Fan, JY; Li, W; Liu, YF; Shen, Z; Wang, G, 2005)
"Erythrodermic psoriasis is an aggressive form of the disease and can be precipitated by numerous factors including stress to the body."( Das, SR; Deiraniya, AK; Jha, PK; Kingston, TP; Lakshmanan, S; Musleh, GS, 2005)
"Psoriasis is a frequent dermatosis, its prevalence is estimated of between 1 and 3 p."( Amal, S; Charioui, S; Hocar, O; Houass, S; Jalal, O; Laissaoui, K, 2005)
"Psoriasis is a chronic, recurrent disease that affects between 1% and 3% of the population."( Griffiths, CE; Naldi, L, 2005)
"Psoriasis is very common and causes substantial morbidity."( Afifi, T; de Gannes, G; Huang, C; Zhou, Y, 2005)
"Psoriasis is believed to be characterized by a type 1 cytokine pattern; interferon-gamma, interleukin (IL)-2 and tumour necrosis factor (TNF)-alpha are predominantly expressed in this disorder."( Namazi, MR, 2005)
"Psoriasis is a genetically determined disease characterized by hyperproliferation and disordered maturation of the epidermis."( Halsall, JA; Hutchinson, PE; Osborne, JE; Pringle, JH, 2005)
"Psoriasis is a common, chronic, distressing skin disorder that frequently affects the scalp, skin, nails and joints."( Kimball, AB; Reid, DC, 2005)
"Psoriasis is a chronic skin disease, whose prevalence in population is connected with interaction between genetic and environmental factors."( Chodorowska, G; Kwiatek, J, 2004)
"Psoriasis is a common skin disorder that may be triggered by hormonal disturbances, among other factors."( Ezquerra, GM; Millet, PU; Regaña, MS, 2005)
"Treatment of nail psoriasis is difficult."( Llambí Mateos, F; Martín Ezquerra, G; Sánchez Regaña, M; Umbert Millet, P, 2005)
"Psoriasis is considered as a T-cell-mediated inflammatory skin disease which is characterized by hyperproliferation and poor differentiation of epidermal keratinocytes."( Wolters, M, 2005)
"Psoriasis is a chronic skin disease with substantial impact on patients' social and relational ways of living and subsequently on their quality of life."( de Boo, T; Krabbe, PF; Prins, M; Swinkels, QO; van de Kerkhof, PC; van der Valk, PG, 2005)
"Inverse psoriasis is a chronic disease frequently treated with topical corticosteroids."( Choi, C; Kwong, PC; Steele, JA, 2005)
"The dogma in psoriasis is that due to pathogen-induced inflammatory responses, an autoreactive immune response is induced that leads to tissue destruction."( Caspary, F; Das, PK; Elliott, G; Nagelkerken, L; Navé, BT; Nieland, JD; Rohrbach, M; Verzaal, P, 2005)
"Psoriasis is a common disease which often requires long-term maintenance therapy."( Asilian, A; Khalesi, E; Khoddami, L; Mohammady, M; Shahtalebi, M; Vali, A, 2005)
"Psoriasis is a chronic, inflammatory, hyperproliferative skin disease that affects 1-2% of the general population in the UK and US."( Ashcroft, DM; Fairhurst, DA; Griffiths, CE, 2005)
"Psoriasis is a chronic inflammatory skin disease whose pathogenesis is modulated by numerous genetic and immunologic factors."( Zargari, O, 2005)
"Psoriasis is associated with abnormal plasma lipid metabolism and a high frequency of cardiovascular events."( Allen, MH; Barker, JN; Burden, AD; Campalani, E; Crook, MA; Fairhurst, D; Griffiths, CE; Mendonca, CO; Smith, CH; Young, HS, 2006)
"The cause of psoriasis is still unknown."( Abuhamida, M; Alhaddar, J; Duweb, G, 2005)
"Psoriasis is characterized by three main pathogenic features: abnormal differentiation, keratinocyte hyperproliferation and inflammation."( Abuhamida, M; Alhaddar, J; Duweb, G, 2005)
"Psoriasis is known to be an autoimmune skin disease characterized by Th1 cell-mediated hyperproliferation of keratinocytes, and the type 1 helper T (Th1) cell subset increased with imatinib therapy."( Akiyama, T; Fujimi, A; Kida, M; Kuroda, H; Matsunaga, T; Niitsu, Y; Sato, T; Shimizu, K; Shirao, S; Tanaka, I; Watanabe, H, 2005)
"Psoriasis is one of the most frequent inflammatory skin diseases in which abnormal individual immune reactivity plays an important role."( Andrýs, C; Borská, L; Ettler, K; Fiala, Z; Hamáková, K; Krejsek, J; Kremlácek, J; Vokurková, D, 2006)
"Psoriasis is a T-cell-mediated autoimmune disease, but certain medications and infections are well-known risk factors."( Luba, KM; Stulberg, DL, 2006)
"Psoriasis is a chronic inflammatory dermatosis that affects 0."( Guillen, S; Khachemoune, A, 2006)
"Palmoplantar psoriasis is a chronic disease, which is very resistant to treatment and often leads to severe disabilities."( Korpusik, D; Mahnke, N; Neumann, NJ; Ruzicka, T; Stege, H, 2006)
"Psoriasis is a chronic inflammatory skin disorder of multifactorial etiology."( Farshi, S; Mansouri, P, 2006)
"Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life."( Bardazzi, F; Dika, E; Maibach, HI; Varotti, C, 2006)
"As psoriasis is a chronic disease, long-term treatment may be required, so there is a need to investigate the safety of its use over a longer period of time."( Austad, J; Barnes, L; Bibby, A; Cambazard, F; de la Brassinne, M; Fleming, C; Heikkilä, H; Jolliffe, D; Kragballe, K; Peyri, J; Svensson, A; Toole, J; Wozel, G, 2006)
"Psoriasis is a T-helper (Th)1 cytokine-mediated chronic skin disease and interleukin (IL)-12 has been shown to play a major role in the development of Th1 responses."( Asahina, A; Kishimoto, E; Komine, M; Mitsui, H; Saeki, H; Tada, Y; Takekoshi, T; Tamaki, K, 2006)
"Psoriasis is a chronic skin disease that often requires long-term therapy to control the symptoms."( Aydin, F; Canturk, T; Senturk, N; Turanli, AY, 2006)
"Since treatment of psoriasis is generally long-term, the objective of this study was to investigate the efficacy and safety of transferring patients to maintenance treatment with calcipotriene cream (Dovonex cream) following a 4-week treatment period with the two-compound product."( Bibby, A; Cambazard, F; Foster, R; Haverkamp, C; Martinez Escribano, JA; Naeyaert, JM; Thaçi, D; Vender, R; White, S, 2006)
"Psoriasis is a T cell mediated inflammatory skin disease characterized by hyperproliferation and reduced differentiation of epidermal keratinocytes."( Wolters, M, 2006)
"Psoriasis is a common skin condition affecting approximately 2."( Janiga, J; Lim, HW; Rivard, J, 2006)
"Psoriasis is characterized by the hyperproliferation of keratinocytes in the epidermis and the accumulation of activated CD4+ T lymphocytes in the upper dermis."( Cai, JP; Chin, YH; Falanga, V, 1990)
"Psoriasis is a systemic chronic inflammatory disorder."( Bock, D; Philipp, S; Wolff, G, 2006)
"Psoriasis is a common cutaneous disorder characterized by abnormal epidermal differentiation, proliferation and inflammation mediated by dermal infiltrates, such as T cells, neutrophils, dendritic cells and macrophages."( Bevelacqua, V; Curatolo, S; Gangemi, P; La Greca, S; Libra, M; Malaponte, G; Massimino, D; Mazzarino, MC; Merito, P; Nicotra, G; Plumari, A; Stivala, F; Valente, G, 2006)
"Psoriasis is a common skin disease, the pathogenesis of which has not yet been resolved."( Haase, I; Hartmann, K; Krieg, T; Markur, D; Pasparakis, M; Peters, T; Rupec, RA; Scharffetter-Kochanek, K; Stratis, A; van Rooijen, N, 2006)
"Psoriasis is a chronic, recurrent, inflammatory, and hyperproliferative disease."( Gurer, MA; Ilter, N; Ozden, MG; Sancak, B; Tekin, NS, 2006)
"Psoriasis is a complex disease that requires safe, long-term treatment."( Gorgievska Sukarovska, B; Lipozencić, J, 2006)
"The pathogenesis of psoriasis is incompletely understood but cutaneous neurogenic inflammation is probably involved."( Griffiths, CE; Kleyn, CE; Saraceno, R; Terenghi, G, 2006)
"Currently, psoriasis is seen as a T-cell-mediated autoimmune disease that is characterized by an increased expression of pro-inflammatory cytokines."( Dissemond, J; Grabbe, S, 2006)
"Psoriasis is an inflammatory disease also characterised in part by epidermal keratinocyte hyper-proliferation."( Wilkinson, JD; Williamson, EM, 2007)
"Thyroid disease and psoriasis are common associated conditions."( Oakley, A; Simpkin, S, 2007)
"Psoriasis is an immune-mediated disease with a chronic relapsing course, and the particularly severe forms that are refractory to traditional therapies are often difficult to manage."( Altomare, A; Altomare, GF; Colombo, MD; Franchi, C; Frigerio, E; Garutti, C, 2007)
"Psoriasis is a chronic inflammatory skin disease in which several Th1 cytokines such as interleukin-1 beta (IL-beta) have been shown to play a pivotal role."( Alicino, D; Mastrolonardo, M; Pasquini, P; Picardi, A; Zefferino, R, 2007)
"Comorbid RA and psoriasis are unusual, and our patients exhibited a clear link between anti-TNF-alpha administration and cutaneous lesions, suggesting a direct effect in both cases."( Albert, C; Breuil, V; Brocq, O; Euler-Ziegler, L; Euller-Ziegler, L; Giacchero, D; Lacour, J; Leccia, N; Perrin, C; Roux, CH, 2007)
"Psoriasis is a common disease in children and adolescents."( Ceović, R; Husar, K; Kostović, K; Lipozencić, J; Murat-Susić, S; Pasić, A; Skerlev, M, 2006)
"Psoriasis is a chronic skin disorder affecting up to 2."( Koo, J; Leon, A; Letsinger, J; Nguyen, A, 2007)
"Psoriasis is a frequent, chronic, clinically variable inflammatory disease of unknown etiology, affecting primarily the skin and the joints."( Gyulai, R; Kemény, L, 2006)
"Psoriasis is characterised by the presence of neutrophil overactivation and overproduction of interleukin (IL)-6 and IL-8 from keratinocytes."( Alli, N; Artuz, F; Gür, G; Lenk, N; Polat, M; Tamer, E; Yalcin, B, 2007)
"AA and psoriasis are rare in our series."( Chen, W; Cheng, YW; Lai, CS; Yang, YC, 2007)
"Psoriasis is a chronic inflammatory skin disease characterized by an accelerated turnover of epidermal cells and an incomplete differentiation in epidermis with lesion."( Barut, F; Sipahi, EY; Tekin, IO; Tekin, NS, 2007)
"Nail psoriasis is common in adult psoriatic patients and it causes serious psychological and physical distress."( Berth-Jones, J; Vlachou, C, 2007)
"Psoriasis is a common skin disease affecting 1%-3% of the world's population with significant impacts on quality of life."( Toole, JW, 2007)
"Psoriasis is a chronic skin disease that affects millions of people throughout the world."( Jiaravuthisan, MM; Muhn, CY; Murphy, F; Sasseville, D; Vender, RB, 2007)
"Psoriasis is characterized by excessive proliferation of keratinocytes accompanying acanthosis and incomplete differentiation."( Hwang, HY; Kim, SY; Kim, TY; Kim, Y, 2007)
"Psoriasis is a chronic skin disorder affecting approximately 2% of the US population."( Balin, AK; Clark, SD; Fleming, T; Flores, J; Glinert, RJ; Graeber, M; Kempers, S; Lebwohl, M; Liu, Y; Menter, A; Pariser, DM; Powers, J; Weiss, J, 2007)
"Psoriasis is a common, chronic, relapsing, papulo-squamous dermatitis, with overlying silvery scales."( De Rosa, G; Mignogna, C, 2007)
"Facial psoriasis is a prognostic marker indicating a poor prognosis of psoriasis."( Austad, J; Cambazard, F; Duvold, LB; Ljungberg, A; Murphy, GM; van de Kerkhof, PC, 2007)
"Psoriasis is a chronic inflammatory skin disease characterized histologically by hyperproliferation and aberrant differentiation of epidermal keratinocytes."( Che, CT; Cheng, CH; Lin, ZX; Tse, WP; Zhao, M, 2007)
"Psoriasis is a common chronic inflammatory skin disease."( El-Shabrawi, Y; Hofer, A; Kerl, H; Renner, W; Salmhofer, W; Weger, W; Wolf, P, 2007)
"Psoriasis is a chronic inflammatory cutaneous disorder."( Ben Osman Dahri, A; Boubacker, MS; Cherif Ben Hmida, F; Hechmi-Louzir, M; Samoud El Kissi, S, 2007)
"Psoriasis is a chronic inflammatory skin disease, where specific immunity and/or innate immunity may be of importance in the disease pathogenesis."( Nordlind, K; Thorslund, K, 2007)
"Hand and foot psoriasis is a chronic and debilitating disease that manifests as plaque-type or pustular-type lesions."( Kircik, L, 2007)
"Psoriasis is a multifactorial disease in which genetic and inflammatory factors play important roles."( Aydin, F; Bagci, H; Bek, Y; Canturk, MT; Gunes, S; Kara, N; Senturk, N; Turanli, AY, 2007)
"Cutaneous psoriasis is an example, of which several cases have been reported."( Aubin, F; Balblanc, JC; Briançon, D; Brousse, A; Deprez, P; Humbert, P; Lohse, A; Wendling, D, 2008)
"Psoriasis is a class effect that has been reported with all the currently available TNFalpha antagonists."( Aubin, F; Balblanc, JC; Briançon, D; Brousse, A; Deprez, P; Humbert, P; Lohse, A; Wendling, D, 2008)
"While psoriasis is one of the most common skin disorders in humans, effective, safe and inexpensive treatments are still largely unavailable."( Chang, S; Demerjian, M; Elias, PM; Feingold, KR; Lee, SH; Man, M; Man, MQ; Shi, Y, 2008)
"Psoriasis is an immune mediated, inflammatory skin condition affecting approximately 1."( Alegre de Miguel, V; Martínez Casimiro, L; Sánchez Carazo, JL, 2008)
"Psoriasis is a complex genetic disease of unresolved pathogenesis with both heritable and environmental factors contributing to onset and severity."( Blakytny, R; Holmdahl, R; Kess, D; Lindqvist, AK; Peters, T; Scharffetter-Kochanek, K; Sindrilaru, A; Wang, H; Wlaschek, M, 2008)
"Psoriasis is a lifelong, chronic and immune-mediated skin disease affecting approximately 1-3% of the Caucasian population."( Chimenti, S; De Lorenzo, A; Di Renzo, L; Esposito, M; Mazzotta, A; Saraceno, R; Schipani, C, 2008)
"Psoriasis is a common chronic inflammatory disease of the skin characterized by epidermal hyperplasia and angiogenesis."( Bu, ZY; Cai, SQ; Man, XY; Yang, XH; Zheng, M, 2008)
"Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population."( Beutner, KR; Bhushan, R; Elmets, CA; Feldman, SR; Gordon, KB; Gottlieb, A; Koo, JY; Korman, NJ; Lebwohl, M; Leonardi, CL; Menter, A; Van Voorhees, AS, 2008)
"Psoriasis is a common chronic inflammatory skin disease, characterized by epidermal hyperplasia, immune cell infiltration, increased dermal angiogenesis and local up-regulation of a variety of inflammatory mediators."( Hvid, H; Kemp, K; Kvist, PH; Svensson, L; Teige, I, 2008)
"Psoriasis is an important disorder in the adolescent population and has a tremendous physical and psychological impact on patients."( Belazarian, L, 2008)
"Psoriasis is likely associated with an increased risk of myocardial infarction, metabolic syndrome, Crohn's disease, and depression; it is difficult to assess the implications in the adolescent population."( Belazarian, L, 2008)
"Psoriasis is not rare in the adolescent population."( Belazarian, L, 2008)
"Psoriasis is a common chronic and recurrent inflammatory skin disease associated with increased thrombosis."( Dogan, B; Erikci, AA; Harmanyeri, Y; Karabudak, O; Solmazgul, E; Ulusoy, RE, 2008)
"Psoriasis is a chronic skin disease characterized by a thickening and disorganization of the skin's protective barrier."( Jean, J; Lapointe, M; Pouliot, R; Soucy, J, 2009)
"Psoriasis is a disease presenting cutaneous, immunological and vascular abnormalities."( Ohtsuka, T, 2008)
"As psoriasis is considered an autoimmune disease, lower levels of soluble HLA-G (sHLA-G) might be expected in psoriatic patients than in healthy controls."( Altieri, E; Baricordi, O; Borghi, A; Fogli, E; Melchiorri, L; Rizzo, R; Stignani, M; Virgili, A, 2008)
"Psoriasis is a disorder characterized by faster than normal skin growth, resulting in a buildup of thickened areas with a scaly appearance."( Draelos, ZD, 2008)
"Psoriasis is a common, chronic inflammatory skin disease that affects the scalp more commonly than any other site."( Brown, BC; Griffiths, CE; Warren, RB, 2008)
"Chronic plaque psoriasis is frequently associated with obesity."( Del Giglio, M; Di Francesco, V; Girolomoni, G; Gisondi, P; Zamboni, M, 2008)
"Psoriasis is highly prevalent and is associated with skin-associated complaints as well as arthritis, depression and a lower quality of life."( Federman, DG; Gunderson, CG; Kirsner, RS; Prodanovich, S; Shelling, M, 2009)
"Linear psoriasis is a very unusual clinical variation of psoriasis."( Bröcker, EB; Garbaraviciene, J; Hamm, H; Seitz, CS, 2009)
"Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of plasmacytoid dendritic cells (pDC) into the skin."( Albanesi, C; Bosisio, D; Daniele, R; De Pità, O; Fortugno, P; Franssen, JD; Girolomoni, G; Gonzalvo-Feo, S; Madonna, S; Pallotta, S; Parmentier, M; Scarponi, C; Sozzani, S, 2009)
"Psoriasis is an inflammatory skin disorder characterized by increased activation of CD4(+) T lymphocytes, and systemic and local overexpression of pro-inflammatory cytokines such as interleukin 2 (IL-2), gamma interferon (IFN-gamma), IL-6 and tumour necrosis factor alpha, indicating that immunopathogenesis of the disease is T helper 1 (Th1) mediated."( Bhattacharya, SN; Das, S; Jain, S; Kaur, IR; Singh, A, 2009)
"Psoriasis is a chronic disease characterized by abnormal epidermal proliferation, inflammation and angiogenesis."( Abdalmoati, A; Al-Makhzangy, I; Attwa, E; Nassar, A; Nofal, A, 2009)
"Psoriasis is a common chronic and recurrent inflammatory skin disease with unknown etiology that has been associated with abnormal plasma lipid metabolism and oxidative stress."( Akçay, F; Aksoy, H; Kadi, M; Toker, A; Yildirim, AK, 2009)
"Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and infiltration of inflammatory leukocytes."( Higaki, M; Higaki, Y; Kawashima, M, 2009)
"Psoriasis is a chronic inflammatory disease causing important physical and psychological morbidity."( Laffitte, E; Thielen, AM, 2009)
"Nail psoriasis is often refractory to traditional treatments, and patients with nail psoriasis usually demand a therapeutic option."( Fernández-Guarino, M; García-Morales, I; Harto, A; Jaén, P; Sánchez-Ronco, M, 2009)
"Plaque-type psoriasis is a chronic and immune-mediated skin disease affecting approximately 1-3% of the Caucasian population."( Chimenti, S; Frascione, P; Gramiccia, T; Saraceno, R, 2009)
"Psoriasis is a very common dermatological disease affecting a large part of the world population."( Buggiani, G; Lotti, T; Prignano, F, 2009)
"Scalp psoriasis is reported to occur in 50-80% of psoriasis sufferers."( Brouda, I; Edison, B; Green, B; Johnson, C, 2009)
"Psoriasis is characterized by an accelerated keratinocyte proliferation, resulting in increased epidermal thickness."( Dagnaes-Hansen, F; Dam, TN; de Darkó, E; Kamp, S; Rosada, C; Stenderup, K, 2010)
"Psoriasis is strongly associated with streptococcal throat infection, and patients have increased occurrence of such infections."( Gudjonsson, JE; Johnston, A; Sigurdardottir, SL; Thorleifsdottir, RH; Valdimarsson, H, 2009)
"Erythrodermic psoriasis is a severe and disabling variant of psoriasis."( Calvieri, S; Carboni, V; Carlomagno, V; Giancristoforo, S; Maiani, E; Mattozzi, C; Richetta, AG, 2009)
"Psoriasis is a common and chronic immune-mediated skin disorder, for which there is currently no cure."( Chan, HH; Ho, SG; Yeung, CK, 2010)
"Psoriasis is a common chronic inflammatory disease that is associated with serious comorbidities, including psoriatic arthritis, reduced quality of life, depression, malignancy, and cardiovascular comorbidities."( Dann, F; Gottlieb, AB, 2009)
"Psoriasis is a skin disease associated with hyperproliferation and aberrant differentiation of keratinocytes."( Che, CT; Cheng, CH; Fan, RQ; Ho, WK; Jiao, BW; Lam, KY; Lin, ZX; Mok, CF; Tse, WP; Yang, ZJ; Zhao, M; Zuo, Z, 2010)
"Psoriasis is a chronic inflammatory skin disease characterised by elevated red scaly plaques on specific body sites."( Prens, EP; Rácz, E, 2009)
"Blaschko-linear psoriasis is a rare disease about which only a few publications have appeared in the literature."( Cribier, B; Guillaume, JC; Roth-Mall, B; Sfia, M; Tortel, MC, 2009)
"Psoriasis is a chronic, recurring inflammatory disease affecting the skin, joints and nails that has a significant negative impact on the quality of life."( Kanwar, AJ; Kaur, I; Mahajan, R, 2010)
"Psoriasis is a papulosquamous disease of multifactorial etiology."( Charrow, EJ; Forman, L; Lal, S; Lamba, G; Palaniswamy, C; Shah, D; Singh, T; Vinnakota, R, 2011)
"(1) Plaque psoriasis is the most common form of psoriasis in children."( , 2009)
"Psoriasis is well-known immune-mediated skin disease often associated with co-morbidities, including dyslipidaemia and obesity."( Chodorowska, G; Dybiec, E; Jastrzebska, I; Juszkiewicz-Borowiec, M; Krasowska, D; Maciejewski, R; Pietrzak, A; Schwartz, RA, 2009)
"Psoriasis is a disease characterized by epidermal hyperproliferation that results in the formation of lesional plaques covered by scale."( Fournier, C; Tisman, G, 2010)
"Psoriasis is an immune-mediated disease typically associated with cutaneous neutrophilic infiltration and Munro microabscesses."( Ferran, M; Galván, AB; Giménez-Arnau, A; Pujol, RM; Santamaría-Babi, LF, 2010)
"Psoriasis is a chronic, systemic inflammatory disorder manifesting primarily in skin and potentially in joints, frequently necessitating treatment with conventional systemic therapies, phototherapy or biological agents."( Cooper, AJ; Dolianitis, C; Foley, PA; Hack, SP; Quirk, C; Sullivan, JR; Thirunavukkarasu, K, 2010)
"Psoriasis is a skin disorder that is associated with arthritis."( Akman, A; Alpsoy, E; Cay, HF; Cevikol, C; Kaçar, C; Kocabaş, H; Melikoğlu, MA; Sezer, I, 2010)
"Psoriasis is a chronic inflammatory disease of the skin."( Hou, R; Jia, Y; Li, X; Niu, X; Yin, G; Zhang, J; Zhang, K, 2010)
"Psoriasis is a chronic inflammatory disease in which pruritus is a common symptom."( Amatya, B; El-Nour, H; Nigam, R; Nordlind, K, 2010)
"Psoriasis is a hyperproliferative, cutaneous disorder with the potential to lower levels of folate."( Graham, IM; Hand, EB; Hughes, R; Kirby, B; Leong, T; Tobin, AM, 2011)
"Childhood psoriasis is common, but it has not been adequately reported in China."( Feng, AP; Huang, CZ; Li, JW; Lin, Y; Liu, HJ; Wu, Y, 2010)
"Psoriasis is a chronic and relapsing inflammatory skin disease associated with various immunologic abnormalities."( Chen, XC; Chen, XJ; Deng, HX; Huang, NY; Kan, B; Li, J; Li, XL; Li, Y; Liu, CY; Mao, YQ; Qiu, J; Wang, YS; Wei, YQ; Wen, YJ; Yang, HS; Yang, L; Zhang, Y; Zhang, YB; Zhao, X; Zhou, XK, 2010)
"Psoriasis is a chronic inflammatory skin disease, which affects approximately 2."( Jensen, P; Skov, L; Zachariae, C, 2010)
"Psoriasis is a noncontiguous common and chronic skin disorder."( Afridi, HI; Arain, MB; Baig, JA; Jamali, MK; Kandhro, GA; Kazi, N; Kazi, TG; Khan, S; Kolachi, NF; Shah, AQ; Shah, F; Wadhwa, SK, 2011)
"Hand and foot psoriasis is a disabling condition associated with significant quality-of-life issues."( Di Lernia, V; Guareschi, E, 2010)
"Psoriasis is a common disorder affecting 1-3 percent of the general global population."( Enshaieh, S; Faghihi, G; Iraji, F; Joia, A; Shahmoradi, Z; Siadat, AH; Soleimani, F, 2010)
"Psoriasis is a common disease with the population prevalence ranging from 2% to 3%."( Chodorowska, G; Michalak-Stoma, A; Pietrzak, A; Szepietowski, JC, 2010)
"Psoriasis is a chronic, debilitating disease that commonly involves the scalp."( Kircik, LH; Kumar, S, 2010)
"Psoriasis is a common skin disease affecting about 1-3% of the world population."( Glowacka, E; Lewkowicz, P; Rotsztejn, H; Zalewska, A, 2010)
"Psoriasis is a prevalent chronic inflammatory condition that affects the skin."( Smith, CH; Woolf, RT, 2010)
"Psoriasis is a common chronic skin disease characterized by recurrent erythromatous skin plaques that exhibit epidermal hyperplasia, variable inflammatory cell infiltrate, and abnormalities of the dermal vascularization."( Keshavarz, M; Mansouri, K; Motlagh, HR, 2011)
"Psoriasis is associated with premature atherosclerosis although the underlying mechanism remains unclear."( Chan, HH; Chan, HT; Lam, KF; Tam, S; Tse, HF; Wong, RM; Yan, GH; Yeung, CK; Yiu, KH; Yue, WS, 2011)
"Psoriasis is a chronic and recurrent inflammatory skin disease, known as an oxidative stress condition."( Attwa, E; Swelam, E, 2011)
"Psoriasis is thought to be associated with an increased risk of lymphoma."( Brocard, A; Dréno, B; Knol, AC; Peuvrel, L; Quéreux, G; Renaut, JJ, 2010)
"Psoriasis is a common skin disorder; knowledge of the factors that may induce, trigger, or exacerbate the disease is of primary importance in clinical practice."( Ashok, NM; Basavaraj, KH; Praveen, TK; Rashmi, R, 2010)
"Psoriasis is a common chronic inflammatory skin disease and many patients require lifelong treatment."( Freeman, K, 2011)
"Scalp psoriasis is difficult to treat."( Affleck, AG; Auland, M; Bottomley, JM; Jackson, P; Ryttov, J, 2011)
"Severe psoriasis is associated with significant cardiovascular mortality."( Beschmann, H; Boehncke, S; Boehncke, WH; Diehl, S; Fichtlscherer, S; Garbaraviciene, J; Hardt, K; Salgo, R; Thaçi, D, 2011)
"Psoriasis is an inflammatory hyperproliferative skin disorder with a strong genetic predisposition."( O'Rielly, DD; Rahman, P, 2011)
"Psoriasis is a common, chronic disease which affects nearly 3% of the population."( Oz, A; Sarıcaoglu, H; Turan, H, 2011)
"Severe psoriasis is associated with significant cardiovascular mortality."( Beschmann, H; Boehncke, S; Boehncke, WH; Diehl, S; Fichtlscherer, S; Garbaraviciene, J; Hardt, K; Salgo, R; Thaçi, D, 2011)
"The pathogenesis of psoriasis is thought to depend on the activation of immune cells and their secreted cytokines, chemokines and growth factors like IGF-1 which may contribute to the epidermal hyperplasia of psoriasis."( Amin, I; El-Komy, M; Kadry, D; Shaker, O; Zeid, OA; Zidan, A, 2011)
"Psoriasis is a chronic inflammatory, immune-mediated skin disease, which affects 2%-3% of the population worldwide."( Ferrazzi, A; Girolomoni, G; Gisondi, P, 2010)
"Psoriasis is a hyperproliferative and inflammatory skin disorder that affects roughly 2 percent of the worldwide population."( Brodell, RT; Bruce, S; Colón, LE; Gottschalk, RW; Hudson, CP; Johnson, LA; Weiss, JS, 2011)
"Childhood psoriasis is a well-known entity, which is different from adult onset psoriasis in many ways."( Augustin, M; Beikert, F; Fölster-Holst, R; Herberger, K; Radtke, MA, 2011)
"Psoriasis is a chronic immune-mediated inflammatory skin disorder affecting approximately 2% of the population worldwide."( Lotti, T; Pescitelli, L; Prignano, F; Ricceri, F; Ruffo, G, 2011)
"Psoriasis is an inflammatory disease associated with abnormalities in lipid profile, lipid peroxidation, antioxidant capacity, eicosanoid metabolism and increased frequency of cardiovascular events."( Aukrust, P; Berge, RK; Bohov, P; Livden, JK; Morken, T; Skorve, J; Ulvik, R, 2011)
"Psoriasis is an inflammatory disease with dynamic interactions between the immune system and the skin."( Benson, JM; DiGiovanni, J; Elloso, MM; Gutshall, LL; Iwakura, Y; Kamijima, R; Kanda, T; Miyoshi, K; Nakajima, H; Nakajima, K; Naso, MF; Sano, S; Shiga, T; Takaishi, M; Tarutani, M, 2011)
"Palmoplantar psoriasis is a difficult to treat variant of plaque psoriasis."( Bissonnette, R; Bolduc, C; Guenther, L; Lynde, CW; Nigen, S; Poulin, Y, 2011)
"Scalp psoriasis is a common life-altering skin condition causing a great deal of distress."( Kircik, L, 2011)
"On the other hand, psoriasis is rare, and has been reported to occur within weeks of starting the treatment."( Chong, VH, 2011)
"Psoriasis is a skin disease characterized by the presence of red plaques on the skin."( Jean, J; Pouliot, R; Soucy, J, 2011)
"Moderate to severe psoriasis is associated with increased alcohol intake and excessive mortality from alcohol-related causes."( Collins, P; Cunningham, S; Kirby, B; Mason, DL; McAleer, MA; McCormick, PA; O'Shea, SJ; Rogers, S; Stone, C, 2011)
"Psoriasis is a complex, multifactorial inflammatory skin disease with genetic and environmental interactions."( Kamo, A; Negi, O; Ogawa, H; Takamori, K; Taneda, K; Tengara, S; Tominaga, M, 2011)
"Moderate to severe psoriasis is common in childhood and adolescence and is often a challenge for the treating dermatologist."( Domm, S; Gerdes, S; Mrowietz, U, 2011)
"Psoriasis is now considered a genetically programmed, immune-mediated, inflammatory disease, in which intralesional T lymphocytes trigger keratinocytes to proliferate and perpetuate the disease process."( de Panfilis, G; Di Marcantonio, D; Gobbi, G; Micheloni, C; Mirandola, P; Ruscitti, F; Vaccarezza, M; Vitale, M, 2011)
"Psoriasis is a disorder with genetic and immunologic background."( Abdel Hay, RM; Rashed, LA, 2011)
"In Germany, psoriasis is often treated with systemic corticosteroids though these are not recommended by the S3-guideline."( Augustin, M; Glaeske, G; Radtke, M; Reich, K; Schäfer, I, 2011)
"Psoriasis is a common inflammatory disease with a range of clinical presentations and a chronic relapsing course."( Chiu, MW; Hillman, JD; Monroe, HR, 2011)
"Psoriasis is a very common chronic skin disease, affecting 2-3% of the world's population or more than 125 million individuals worldwide."( Belinka, BA; Dam, TN; Kachlany, SC; Rosada, C; Salerno, E; Stenderup, K, 2011)
"Psoriasis is a common chronic autoimmune condition of the skin characterized by hyperplasia of epidermal keratinocytes associated with pro-inflammatory cytokines."( Alves-Filho, JC; Asquith, DL; Graham, GJ; Hueber, AJ; Liew, FY; McInnes, IB; Michels, C; Millar, NL; Miller, AM; Reilly, JH, 2011)
"Psoriasis is a chronic, autoimmune skin disease affecting approximately 2% of the world's population."( Badıllı, U; Sen, T; Tarımcı, N, 2011)
"Psoriasis is a chronic inflammatory skin disease that affects approximately 2-4% of the population."( Bacsa, S; Bari, L; Bata-Csörgo, Z; Dobozy, A; Kemény, L; Sonkoly, E; Széll, M, 2011)
"Psoriasis is an autoimmune disease that affects about 2% of the world population."( Cheung, PH; Foreman, O; Hain, HS; Kaur, P; Kavirayani, A; Saha, S; Tung, D, 2011)
"Psoriasis is a chronic condition with serious quality-of-life ramifications."( Colón, LE; Gottschalk, R; Hudson, CP; Johnson, LA; Kempers, S; Menter, A; Papp, K; Smith, S; Sofen, H, 2011)
"As psoriasis is now considered to be a T cell-mediated disease we decided to challenge peripheral blood mononuclear cells (PBMCs) in vitro from randomly selected patients with well-defined wheat proteins/peptides to explore the possibility of identifying a specific antigen with T cell activating properties in a subgroup of patients."( Geisner, B; Marcusson, JA; Marsh, J; Shewry, PR; Skavland, J, 2012)
"Psoriasis is a common inflammatory skin disease and obesity constitutes a risk factor for the disease."( Faurschou, A; Knop, FK; Skov, L; Vilsbøll, T; Zachariae, C, 2011)
"Scalp psoriasis is a difficult to treat and usually chronic manifestation of psoriasis."( Barber, K; Berg, M; Kerrouche, N; Lynde, C; Papp, K; Poulin, Y; Prinz, JC; Rives, VP, 2012)
"Psoriasis is a chronic immune-mediated disease that appears on the skin."( Morimoto, S; Okuro, M, 2011)
"Psoriasis is a frequent inflammatory skin disease of unknown cause determined by multigenic predisposition, environmental factors, and aberrant immune response."( Dziarski, R; Gupta, D; Hurwich, R; Kim, CH; Park, SY, 2011)
"Psoriasis is characterized by lower stratum corneum (SC) hydration and dermal inflammation."( Elias, PM; Luo, W; Lv, C; Man, MQ; Song, S, 2012)
"New-onset psoriasis is extremely rare in hemodialysis (HD) patients, and several trials of dialysis therapies (HD and peritoneal dialysis) in psoriasis have indicated remarkable improvement in skin lesions and well-being even in patients without renal impairment."( Aggelakou-Vaitis, S; Dousdampanis, P; Gellner, K; Triga, K, 2012)
"Psoriasis is an independent risk factor for subclinical atherosclerosis."( Badr, T; El Zohiery, AK; Elhilaly, R; Enany, B, 2012)
"Psoriasis is a common chronic autoimmune skin disease of unknown cause that involves dysregulated interplay between immune cells and keratinocytes."( de Heusch, M; Dumoutier, L; Dunussi-Joannopoulos, K; Fouser, LA; Hendrickx, E; Lemaire, MM; Renauld, JC; Van Belle, AB; Warnier, G, 2012)
"Psoriasis is associated with ischemic heart disease (IHD)."( Chang, YT; Chen, CM; Chen, TT; Chen, YJ; Shen, JL; Wang, CB; Wu, CY, 2012)
"Psoriasis is a chronic skin disease resulting from abnormal immune function and is characterized by the presence of scaly psoriatic plaques which are areas of inflammation and excessive skin production."( Guihen, E; Ho, WL; Hogan, AM; Leahy, MJ; O'Connell, ML; O'Connor, WT; Ramsay, B, 2012)
"Psoriasis is a common, chronic, recurrent, inflammatory, hyper proliferative disorder of the skin, which has a relatively high prevalence in the general population (0."( Aggarwal, RK; Albert, L; Buttar, BS; Gandhi, G; Hasan, Q, 2011)
"Psoriasis is an immune-mediated skin disorder frequently associated with obesity and type 2 diabetes (T2D)."( Buysschaert, M; Preumont, V; Tennstedt, D, 2012)
"Psoriasis is a common inflammatory skin disease that is associated with joint, psychiatric, and cardiovascular comorbidities."( Armstrong, AW; Johnson, MA, 2013)
"Psoriasis is a chronic inflammatory disease."( Chen, GS; Chen, YC; Chin, YY; Ko, YC; Lan, CC; Li, WC; Lu, YW; Wu, CS; Yang, YH; Yu, HS, 2012)
"Psoriasis is a Th1 immune-mediated, inflammatory disease, in which skin lesions appear many years before the related metabolic and cardiovascular comorbidities, according to the theory of the 'psoriatic march'."( Campanati, A; Di Primio, R; Gorbi, S; Offidani, A; Orciani, M; Regoli, F, 2012)
"Psoriasis is a common chronic condition of the skin that is resistant to many therapies."( Nilforoushzadeh, MA; Sadeghian, G; Ziaei, H, 2011)
"Psoriasis is a chronic inflammatory skin disease of unknown aetiology, and an active form of vitamin D(3) (1α,25-dihydroxyvitamin D(3)) and its analogues (VD3As) are widely used topical reagents for psoriasis treatment."( Chou, B; Hiromatsu, K; Imafuku, S; Ishii, K; Nakayama, J; Sato-Deguchi, E, 2012)
"Psoriasis is characterized by hyperplasia of the epidermis and infiltration of leukocytes into both the dermis and epidermis."( Barsoum, J; Cardinale, I; Chu, J; Gottlieb, AB; Jacobson, E; Kantor, AB; Khatcherian, A; Krueger, JG; Tatsuta, N; Wada, Y, 2012)
"Psoriasis is a benign, chronic skin disease characterized by keratinocyte hyperproliferation and abnormal differentiation."( Han, J; Hu, J; Sun, J; Zhao, Y; Zhu, Q, 2012)
"Psoriasis is a frequent and often severe autoimmune skin disease, clinically characterized by altered epidermal homeostasis, of which the molecular pathomechanisms are only little understood."( Boehncke, S; Boehncke, WH; Buerger, C; Diehl, S; Hardt, K; Malisiewicz, B; Richter, B; Salgo, R; Woth, K, 2012)
"Psoriasis is a common, relapsing inflammatory skin disease characterized by erythematous scaly plaques."( Becher, B; Haak, S; Heppner, FL; Ingold, B; Kulig, P; Navarini, AA; Pantelyushin, S, 2012)
"Psoriasis is a noncontagious, chronic skin disease affecting 1 in 50 people worldwide."( Afridi, HI; Kazi, N; Kazi, TG; Khan, S; Kolachi, NF; Shah, F; Wadhwa, SK, 2012)
"Psoriasis is a chronic autoimmune hyperproliferative skin disease."( Dayalan, H; Elango, T; Gnanaraj, P; Malligarjunan, H; Subramanian, S, 2012)
"Psoriasis is a common genetic disorder that may be initiated (drug-induced psoriasis) or exacerbated (drug-triggered psoriasis) by some drug intakes."( Piérard, GE; Piérard-Franchimont, C, 2012)
"Psoriasis is a chronic, inflammatory skin condition with negative impacts both physical and psychological."( Kamangar, F; Koo, JY; Nguyen, TV; Wong, JW, 2012)
"Psoriasis is a chronic immunoinflammatory disease that affects 2-3% of the population and shares pathophysiologic mechanisms and risk factors with cardiovascular diseases."( Ahlehoff, O; Gislason, G; Hansen, PR; Lindhardsen, J; Skov, L, 2012)
"Psoriasis is a multi-systemic chronic inflammatory skin disease targeting 2% to 3% of the general population."( Kircik, LH; Onumah, N, 2012)
"  Psoriasis is an inflammatory disease of the skin and joints."( Anandan, S; Madanagobalane, S, 2012)
"Psoriasis is a systemic disease associated with metabolic disorders and vascular complications."( Chen, GS; Ko, YC; Lan, CC; Li, WC; Lu, YW; Su, YS; Wu, CS; Yang, YH; Yu, HS, 2013)
"Psoriasis is a common skin disorder characterized by chronic inflammatory lesions that are frequently vexing for patients and difficult for physicians to treat."( Feldman, S; Pellerin, M; Shutty, B; West, C, 2012)
"Psoriasis is a chronic inflammatory skin disease characterized by excessive cellular replication."( Amani, M; Ebrahimi, A; Eftekhari, K; Khodarahmi, R; Nemati, H; Rahmani, A, 2013)
"Psoriasis is a chronic, recurrent skin disorder, with a poorly understood pathogenesis."( Basavaraj, KH; Rashmi, R; Yuti, AM, 2012)
"Psoriasis is a chronic immune-mediated disease of unknown etiology that affects the skin and mucous membranes."( Brown, GC; Dreyer, LN, 2012)
"Psoriasis is a chronic, immune-mediated skin disease characterized by production of reactive oxygen species due to the activation of tumor necrosis factor alpha (TNF-α), which is thought to be an important factor in inducing and maintaining psoriatic lesions."( Erturan, İ; Flores-Arce, M; Nazıroğlu, M; Tamtürk, B; Yıldız, K, 2012)
"Patients with psoriasis are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism."( Asefi, M; Bahrehmand, F; Ebrahimi, A; Kiani, A; Nomani, H; Pourmotabbed, T; Rahimi, Z; Tavilani, H; Vaisi-Raygani, A, 2012)
"Psoriasis is a Th-1/17 mediated inflammatory disease associated with increased risk of cardiovascular disease (CVD)."( Baer, A; DerOhannesian, S; Farver, W; Gelfand, JM; Krishnamoorthy, P; Li, R; Mehta, NN; Rader, DJ; Raper, A; Reilly, MP; Rodrigues, A; VanVoorhees, A; Wilcox, M; Wolfe, M; Yu, Y, 2012)
"Psoriasis is among the top dermatologic diagnoses for older adult patients, and the number of older adult psoriasis patients is expected to rise."( Davis, SA; Feldman, SR; Koo, JY; Wong, JW, 2012)
"Psoriasis is a chronic inflammatory skin disease that is characterized by thickened red plaques covered with silvery scales."( Bhutani, T; Koo, JY; Nguyen, TV; Wong, JW, 2012)
"Psoriasis is a chronic inflammatory skin disease that is thought to be related to oxidative stress."( Baek, JO; Byamba, D; Kim, TG; Lee, MG; Wu, WH, 2012)
"Psoriasis is a chronic inflammatory disorder associated with cardiovascular morbidity and mortality."( Ahlehoff, O; Dam, TN; Gislason, G; Gniadecki, R; Hansen, PR; Iversen, L; Kristensen, SL; Lasthein, S; Lindhardsen, J; Skov, L; Torp-Pedersen, C, 2013)
"Psoriasis is an important systemic inflammatory disease that often leads to severe vascular diseases."( Chen, GS; Chin, YY; Ko, YC; Lan, CC; Li, WC; Lu, YW; Wu, CS; Yang, YH; Yu, HS, 2013)
"Psoriasis is a chronic inflammatory skin disease triggered by interplay between immune mediators from both innate and adaptive immune systems and skin tissue, in which the IL-23/IL-17 axis is critical."( Dapavo, P; Hirsch, E; Ji, H; Okkenhaug, K; Perino, A; Roller, A; Soro, E, 2012)
"Psoriasis is an autoimmune disease mediated mainly by dysfunctional peripheral blood T cells."( Hou, R; Li, J; Li, X; Yin, G; Zhang, J; Zhang, K, 2012)
"Psoriasis is a chronic inflammatory multisystem disease involving skin and joints affecting 1-3 % of the world population."( Al-Haddad, A; Al-Mutairi, N, 2013)
"Psoriasis is a chronic inflammatory disease associated with increased risks of myocardial infarction and stroke."( Bissonnette, R; Bolduc, C; Guertin, MC; Harel, F; Pressacco, J; Tardif, JC, 2013)
"Psoriasis is a chronic relapsing inflammatory skin disorder affecting 2-3% of world population."( Thapa, RK; Yoo, BK, 2014)
"Psoriasis is a chronic recurrent inflammatory skin disorder with multifactorial etiology, including genetic background, environmental factors, and immune system disturbances with a strong cytokine component."( Andersen, ML; Araújo, MS; Hirotsu, C; Rydlewski, M; Tufik, S, 2012)
"In addition, psoriasis is characterized by an upregulation of STAT3 signaling pathway that is related to the epidermal hyperplasia."( Andrés, RM; Herrero, M; Montesinos, MC; Navalón, P; Payá, M; Terencio, MC; Ubeda, A; Vergés, J, 2013)
"Psoriasis is a chronic, inflammatory skin disease with a significant impact on health-related quality of life (HRQoL)."( Harness, J; Mamolo, C; Menter, A; Tan, H, 2014)
"Psoriasis is a chronic, inflammatory disease affecting 2-3% of the worldwide population, and it may worsen with HIV or be detected as HIV cutaneous manifestation."( Cannizzaro, MV; Chimenti, S; Chiricozzi, A; Giunta, A; Nisticò, SP; Saraceno, R, 2012)
"Psoriasis is a chronic papulosquamous cutaneous disease."( Lovoshitski, R; Rozenman, D; Ziv, M; Zoabi, A, 2012)
"Psoriasis is a chronic proliferative skin disease and is usually treated with topical glucocorticoids, which act through the glucocorticoid receptor (GR), a component of the physiological systems essential for immune responses, differentiation, and homeostasis."( Cai, SQ; Chen, JQ; Landeck, L; Li, CM; Li, W; Man, XY; Mu, Z; Zhang, KH; Zheng, M; Zhou, J, 2013)
"Psoriasis is a chronic inflammatory skin disease that involves the induction of T-helper 1 (Th1) and T-helper 17 (Th17) cell responses and the aberrant expression of proinflammatory cytokines, including IL-1β."( Agrawal, S; Bhagat, L; Jiang, W; Kandimalla, ER; La Monica, N; Tang, JX; Yu, D; Zhu, FG, 2013)
"Psoriasis is an immune-mediated, chronic, inflammatory skin disease which affects approximately 2% of the world's population."( Chan, LC; Chang, CC; Heng, A; Tang, MM, 2013)
"Nail psoriasis is difficult to treat."( Chiang, YY; Chou, CL; Huang, YC, 2013)
"Psoriasis is a common skin disease that can also involve the nails."( Bogaards, NA; de Vries, AC; Hooft, L; Lebwohl, M; Pasch, M; Spuls, PI; Velema, M, 2013)
"Radiotherapy for psoriasis is not used in common practice."( Bogaards, NA; de Vries, AC; Hooft, L; Lebwohl, M; Pasch, M; Spuls, PI; Velema, M, 2013)
"Psoriasis is a chronic inflammatory skin disease with a global prevalence of 2-3%."( Gyldenløve, M; Knop, FK; Skov, L; Vilsbøll, T; Zachariae, C, 2013)
"Psoriasis is a heterogeneous inflammatory disorder that targets the skin and joints."( Tidman, MJ, 2013)
"Pathophysiology of psoriasis is complex and characterized by microscopic, specific changes."( Agozzino, M; Ardigò, M; Berardesca, E; Conti, A; Di Lernia, V; Longo, C; Pellacani, G, 2013)
"Psoriasis is a chronic inflammatory skin disease, most commonly resulting in the occurrence of red and silver scaly plaques."( McCann, FE; McNamee, KE; Palfreeman, AC, 2013)
"Psoriasis is a chronic hyperproliferative inflammatory skin disease, characterized by a generalized redox imbalance."( Barygina, VV; Becatti, M; Fiorillo, C; Lotti, T; Nassi, P; Prignano, F; Soldi, G; Taddei, N; Wright, D, 2013)
"Psoriasis is an inflammatory cutaneous disorder characterized by marked epidermal thickening and Th1 and Th17 cell infiltration."( Asano, Y; Ishiura, N; Kadono, T; Kamata, M; Sato, S; Shibata, S; Sugaya, M; Tada, Y; Tedder, TF; Yanaba, K, 2013)
"Psoriasis is one of the most prevalent immune-mediated illness worldwide."( Perez, JJ, 2013)
"Psoriasis is treated with several classes of treatments that may be used in combination, but the ways combination therapies are used are not well characterized."( Davis, SA; Feldman, SR, 2013)
"Psoriasis is a chronic inflammatory autoimmune disease with undefined etiology."( Hu, J; Li, H; Wen, C; Yang, R; Zhao, H; Zhao, M; Zhou, Q, 2013)
"Psoriasis is a common chronic inflammatory skin disease and its underlying pathogenesis is still not fully understood."( Fu, LX; Tang, DM; Wang, Y; Yan, HX; Yang, XN, 2013)
"Psoriasis is an autoinflammatory skin disease of unknown etiology."( Becher, B; Cheong, C; Clausen, BE; Haak, S; Holzmann, B; Kant, M; Ober-Blöbaum, JL; Onderwater, S; Pantelyushin, S; Prens, EP; Reizis, B; Weighardt, H; Wohn, C; Zahner, SP, 2013)
"Psoriasis is a complex chronic inflammatory skin disease with a worldwide distribution."( Prashant, BS; Saraswathy Devi, S; Sinniah, B, 2010)
"Plaque psoriasis is an inflammatory disease affecting approximately 2% of the population."( Berneburg, M; Eberlein, B; Guenova, E; Herzinger, T; Hoetzenecker, W; Maetzke, J; Meisner, C; Rampf, J; Rocken, M; Schaefer, T; Scharffetter-Kochanek, K, 2013)
"Chronic plaque psoriasis is the most common type of psoriasis and is characterized by redness, thickness and scaling."( Cork, MJ; Dooley, G; Hancock, H; Mason, AR; Mason, JM, 2013)
"Psoriasis is a chronic inflammatory skin disease featuring abnormal keratinocyte proliferation and differentiation."( Austin, HR; Batie, SF; Haussler, MR; Hoss, E; Jurutka, PW; Whitfield, GK, 2013)
"Moderate-to-severe psoriasis is a chronic skin condition that often requires systemic therapy and biologics are the newest systemic treatment available."( Gupta, R; Koo, J; Levin, E; Liao, W; Wu, JJ, 2014)
"Psoriasis is a chronic dermatological disorder that has a negative impact on quality of life (QoL)."( Ismail, R; Low, WY; Min, AK; Nyunt, WW; Sockalingam, S, 2015)
"Psoriasis is a common, chronic, inflammatory skin disease that can have a significant impact on the quality of life of those who are afflicted due to chronicity of the disease and frequent remissions and relapses."( Bhari, N; Khandpur, S, 2013)
"Psoriasis is a chronic inflammatory disease related to genome-wide and surroundings, it is important to develop a suitable animal model to research psoriasis pathogenesis and evolve pharmacotherapeutics."( Hu, JH; Li, H, 2013)
"Psoriasis is a chronic inflammatory disorder associated with increased cardiovascular mortality."( Curcic, S; Heinemann, A; Holzer, M; Inzinger, M; Marsche, G; Pasterk, L; Trieb, M; Weger, W; Wolf, P, 2014)
"Psoriasis is a chronic disease that significantly impacts patients' quality of life."( Ahn, CS; Awadalla, F; Dabade, TS; Feldman, SR; Huang, KE; Yentzer, B, 2013)
"Psoriasis is a chronic inflammatory disorder of the skin and joints."( Chimenti, S; Costanzo, A; Magina, S; Morais, P; Osório, F; Papoutsaki, M; Torres, T, 2013)
"Psoriasis is a chronic, immune-mediated inflammatory and refractory disease."( Hui, Y; Li, CR; Yu, RX, 2013)
"Psoriasis is a chronic, auto-inflammatory disease affecting millions of individuals worldwide."( Laquer, V; Nguyen, T; Ta, T; Tan, B, 2013)
"Psoriasis is an autoimmune, chronic, inflammatory skin disease characterized by epidermal hyperplasia, proliferation of blood vessels, and infiltration of leukocytes in dermis and epidermis."( Garg, T; Goyal, AK; Parnami, N; Rath, G, 2014)
"Psoriasis is a common immune-mediated inflammatory disease that affects the skin and joints."( Agerbeck, C; Bonefeld, CM; Dyring-Andersen, B; Geisler, C; Gúdjonsdottir, SD; Lauritsen, JP; Skov, L, 2014)
"Psoriasis is an inflammatory disease of the skin affecting 2-3% of the population, characterized by a thickening of the epidermis and immune infiltrates throughout the dermis and epidermis, causing skin lesions that can seriously affect quality of life."( Flutter, B; Nestle, FO, 2013)
"Psoriasis is an inflammatory skin disease that may be associated with an adverse cardiometabolic profile including modulated plasma adiponectin and leptin levels."( DerOhannessian, S; Doveikis, J; Gelfand, JM; Krishnamoorthy, P; Li, RC; Mehta, NN; Rader, DJ; Reilly, MP; Thomas, P; Van Voorhees, A; Wilcox, M, 2014)
"Psoriasis is a chronic, immune-mediated inflammatory skin disease affecting 1."( Burden, AD; Burfield, L, 2013)
"Psoriasis is a chronic, systemic and difficult to treat condition which negatively affects the patient's quality of life."( Bartosińska, J; Chodorowska, G; Dreiher, J; Gawlik-Dziki, U; Maciejewski, R; Pietrzak, A; Podhorecka, M; Szepietowski, JC, 2013)
"Psoriasis is a chronic inflammatory skin disease characterised by hyperkeratosis, dermal inflammatory infiltrate and increased angiogenesis."( Dikić, D; Oršolić, N; Skurić, J; Stanić, G, 2014)
"Psoriasis is an inflammatory disease associated with multiple comorbidities and cardiovascular risk factors."( Brown, L; Churton, S; Korman, NJ; Shin, TM, 2014)
"Psoriasis is a complex inflammatory skin disease that presents a wide variety of clinical manifestations."( Bracke, S; Carretero, M; Del Rio, M; Desmet, E; Guerrero-Aspizua, S; Illera, N; Lambert, J; Navarro, M, 2014)
"Psoriasis is a systemic inflammatory immune-mediated skin disease."( Balduzzi, V; Bernardini, N; La Viola, G; Mancini, MT; Nicolucci, F; Pampena, R; Potenza, C; Proietti, I; Skroza, N; Soccodato, V; Tolino, E; Zuber, S, 2013)
"Psoriasis is thought to be initiated by abnormal interactions between the cutaneous keratinocytes and systemic immune cells, triggering keratinocyte hyperproliferation."( Chen, X; Cui, K; Deng, G; Deng, H; Edwards, CK; Guan, T; Hu, Z; Huang, N; Li, J; Liu, N; Liu, X; Luo, C; Sun, C; Teng, X; Wang, X; Wang, Z; Wei, X; Wei, Y; Xu, M; Ye, N; Zhou, X, 2014)
"Psoriasis is most often treated using topical therapies such as the once-daily fixed combination of calcipotriol and betamethasone dipropionate, which is available as a gel and an ointment."( Hol, CW; Lambert, J; Vink, J, 2014)
"Psoriasis is a common chronic inflammatory skin disease that involves dysregulated interplay between immune cells and keratinocytes."( Honda, T; Kabashima, K; Malissen, B; Nakamizo, S; Nakamura, M; Ohmori, S; Sawada, Y; Sugita, K; Tokura, Y; Yoshiki, R; Yoshioka, H, 2014)
"Psoriasis is a common inflammatory skin disease with limited treatment options that is characterized by a complex interplay between keratinocytes, immune cells, and inflammatory mediators."( Concha-Garzón, MJ; Daudén, E; Delgado, Y; Guinea-Viniegra, J; Jiménez, M; Navarro, R; Obad, S; Schonthaler, HB; Tschachler, E; Wagner, EF, 2014)
"Psoriasis is a chronic inflammatory skin disease resulting from immune dysregulation."( Choi, EJ; Hong, MP; Kie, JH; Kim, HR; Lee, A; Lee, HK; Lim, W; Moon, BI; Seoh, JY, 2014)
"Psoriasis is a chronic inflammatory skin disorder mediated by cross-talk occurring between epidermal keratinocytes, dermal vascular cells and immunocytes."( Chowdhari, S; Saini, N, 2014)
"Psoriasis is associated with a systemic inflammation and an increased frequency of the metabolic syndrome, both of which are believed to link psoriasis to an increased risk of cardiovascular disease."( Bivik, C; Ekman, AK; Enerbäck, C; Sigurdardottir, G; Ståhle, M, 2014)
"Psoriasis is an inflammatory skin disease with accelerated epidermal cell turnover."( Abe, J; Ishii, S; Kita, Y; Matsushima, K; Nakamura, M; Sato, S; Shimizu, T; Sumida, H; Yanagida, K, 2014)
"Psoriasis is a chronic inflammatory process associated with an increased risk of cardiovascular risk factors."( Adiloğlu, A; Akkaya, VB; Başak, PY; Ceyhan, AM; Ersoy, IH; Erturan, I; Kilinç, O; Korkmaz, S; Köroğlu, BK; Tamer, N, 2014)
"Psoriasis is associated with increased risk of cardiovascular disease (CVD), possibly due to chronic low-grade systemic inflammation."( Gyldenløve, M; Hansen, PR; Jensen, P; Løvendorf, MB; Skov, L; Zachariae, C, 2015)
"Psoriasis is a chronic T cell-mediated inflammatory skin disease."( Chen, L; Cheng, X; Huang, L; Li, S; Pei, H; Qiu, N; Wang, W; Wang, X; Wen, J; Xie, C, 2014)
"Psoriasis is a chronic debilitating disease in which dermatologists take a frontline role in improving the quality of life of affected patients."( Han, G, 2014)
"Psoriasis is a chronic inflammatory skin disease characterized by excessive proliferation of keratinocytes."( Dong, YY; Guan, LL; Li, HY; Li, XK; Liu, XM; Mmi, XG; Wang, FW; Wang, N; Wang, YF; Xia, JX; Yang, J; Yao, N, 2014)
"Patients with psoriasis are increasingly turning to the use of alternative and complementary medicine to manage their psoriasis."( Bhatia, BK; Debbaneh, M; Koo, J; Liao, W; Millsop, JW, 2014)
"Psoriasis is a common chronic and recurrent inflammatory skin disorder characterized by hyperproliferation of keratinocytes and infiltration of T cells, monocytes/macrophages and neutrophils into dermal and epidermal layers of the skin."( HajHeydari, Z; Hedayati, MT; Shokohi, T; Taheri Sarvtin, M, 2014)
"Psoriasis is a chronic skin disease characterized by keratinocyte hyperproliferation and anti-apoptotic features."( Andrys, C; Borska, L; Borsky, P; Fiala, Z; Hamakova, K; Krejsek, J; Kremlacek, J; Ranna, D, 2014)
"Psoriasis is an autoimmune inflammatory disease which is associated with increased inflammatory markers and atherosclerosis."( Akkoyun, DC; Akyuz, A; Alpsoy, S; Erfan, G; Guzel, S; Kaya, S; Kulac, M; Topcu, B, 2014)
"Psoriasis is a disorder caused by genetic and immunological factors."( Choi, JH; Kim, NI; Lee, JW; Lim, HK; Oh, YJ, 2014)
"Psoriasis is a chronic inflammatory disease that encompasses a large spectrum of clinically distinct subtypes."( Liu, SW; Merola, JF; Patel, M; Qureshi, A, 2014)
"Psoriasis is a chronic inflammatory skin disease with an unknown aetiology that has been associated with abnormal plasma lipid metabolism and oxidative stress."( Ali, E; Ebrahimi, A; Houshang, N; Khodarahmi, R; Mansour, R; Masoud, S; Nemati, H; Reza, K; Rezaei, M; Sadeghi, M; Vaisi-Raygani, A, 2014)
"Psoriasis is a common inflammatory disease that is associated with increased risk of cardiovascular disease, including myocardial infarction."( Ahlehoff, O; Gislason, GH; Hansen, PR; Khalid, U; Kristensen, SL; Skov, L; Torp-Pedersen, C, 2014)
"Psoriasis is a systemic inflammatory skin disease."( Gyldenløve, M; Løvendorf, MB; Røpke, MA; Skov, L; Zibert, JR, 2014)
"As psoriasis is an incurable disease, the goal of the MTX treatment is to suppress psoriasis, achieving long-term remissions with minimal treatment-related adverse events (AEs)."( Baran, W; Batycka-Baran, A; Bieniek, A; Szepietowski, JC; Zychowska, M, 2014)
"Psoriasis is a chronic inflammatory dermatosis leading to the development of systemic inflammatory reaction."( Kacalak-Rzepka, A; Kiedrowicz, M; Maleszka, R, 2013)
"Psoriasis is characterized by an apoptosis-resistant and metabolic active epidermis, while a hallmark for allergic contact dermatitis (ACD) is T cell-induced keratinocyte apoptosis."( Albanesi, C; Cavani, A; Eyerich, K; Eyerich, S; Garzorz, N; Grosber, M; Harlfinger, AT; Jaeger, T; Knapp, B; Mattii, M; Mempel, M; Nasorri, F; Pennino, D; Quaranta, M; Ring, J; Scarponi, C; Schmidt-Weber, CB; Schnopp, C; Theis, FJ, 2014)
"Psoriasis is a chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation and differentiation and by an influx of inflammatory cells."( Ha, HL; Kim, JC; Morasso, MI; Pisitkun, P; Siebenlist, U; Tang, W; Tassi, I; Udey, MC; Wang, H, 2014)
"Psoriasis is a chronic auto-inflammatory skin disease of unknown etiology affecting millions of people worldwide."( Clausen, BE; Ober-Blöbaum, JL; Pantelyushin, S; Wohn, CT, 2014)
"Psoriasis is a common skin disease, which is associated with multiple extracutaneous manifestations."( Filev, FS; Herbert, VG; Klemm, M; Lögering, B; Reich, K; von Gruben, V, 2014)
"Psoriasis is one of the most common inflammatory skin disorders."( Domm, S; Gerdes, S; Mrowietz, U; Steinz, K, 2014)
"Psoriasis is a chronic and inflammatory skin disease."( Akbulak, O; Akdeniz, N; Bilgili, SG; Karadag, AS; Ozkanli, S; Zemheri, E; Zenginkinet, T; Zindanci, I, 2015)
"Psoriasis is a multifactorial process associated with immunologic dysregulation."( Del Rosso, JQ, 2014)
"Psoriasis is a chronic, relapsing, inflammatory skin disease, in which regulatory T cells (Tregs) play an important role."( Fang, X; Han, L; Huang, Q; Ma, Y; Yan, KX; Zhang, HY, 2015)
"Psoriasis is a common disease and is associated with cardiovascular diseases."( Ahlehoff, O; Bryld, LE; Gislason, G; Gniadecki, R; Hansen, PR; Iversen, L; Kristensen, SL; Lasthein, S; Lindhardsen, J; Skov, L; Torp-Pedersen, C, 2015)
"Psoriasis is a T-cell-mediated skin autoimmune disease characterized by the aberrant activation of dermal dendritic cells (DCs) and the sustained epidermal expression of antimicrobial peptides."( Chamilos, G; Conrad, C; Demaria, O; Durr, S; Frasca, L; Ganguly, D; Gilliet, M; Lande, R; Schröder, J, 2015)
"Psoriasis is a common inflammatory hyperproliferative skin disorder that involves cross-talk between different cell types, including immune cells and keratinocytes."( Bollag, WB; Choudhary, V; Helwa, I; Kaddour-Djebbar, I; Karempelis, P; Patel, R, 2015)
"Psoriasis is a common, chronic, inflammatory skin disease with the majority of individuals having limited disease, treated with topical medication."( Bachelez, H; de Jong, EM; Gisondi, P; Mrowietz, U; Puig, L; Reich, K; Warren, RB; Zschocke, I, 2015)
"Psoriasis is frequently associated with obesity, which may favor the development of hyperuricemia."( Gisondi, P, 2014)
"Psoriasis is a chronic inflammatory disease that significantly impacts life quality, being associated with stress and mental disorders."( Benseñor, IM; Brunoni, AR; Lotufo, PA; Sabbag, C; Santos, IS, 2014)
"Psoriasis is a model disease for the development of pharmacogenomic markers of treatment response, with ready access to diseased tissue and objective validated outcome measures."( Foulkes, AC; Warren, RB, 2015)
"Psoriasis is associated with higher CAC values, mainly in individuals with severe psoriasis."( Benseñor, IM; Bittencourt, MS; de Souza Santos, I; Goulart, AC; Lotufo, PA; Sabbag, C; Sharovsky, R; Staniak, HL, 2014)
"Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation and aberrant keratinocyte differentiation."( Adhami, VM; Afaq, F; Chamcheu, JC; Elmets, CA; Mukhtar, H; Pal, HC; Wood, GS, 2015)
"Psoriasis is a common chronic immune-mediated inflammatory disease."( Huo, R; Li, H; Li, N; Shen, B; Sun, Y; Wu, P; Zhai, T; Zhang, J; Zhou, Z; Zhu, X, 2015)
"Psoriasis is a chronic inflammatory disorder of skin and joints for which conventional treatments that are effective in clearing the moderate-to-severe disease are limited due to long-term safety issues."( Adhami, VM; Afaq, F; Ayehunie, S; Boylan, BT; Chamcheu, JC; Elmets, CA; Khan, N; Mukhtar, H; Noubissi, FK; Pal, HC; Siddiqui, IA; Syed, DN; Wood, GS, 2015)
"Psoriasis is a chronic, immune-mediated inflammatory disease that classically presents with well-demarcated, scaly, erythematous plaques on the extensor surfaces of the extremities, scalp, and trunk."( Mahmood, T; Menter, A; Zaghi, D, 2015)
"Psoriasis is a chronic skin disorder that exhibits three main features: lymphocytic infiltration into the dermis and epidermis, uncontrolled proliferation and abnormal differentiation of keratinocytes."( Adone, B; Cozza, V; d'Elia, I; De Filippis, A; Del Giudice, E; Del Giudice, M; Del Giudice, N; Iride, L; Menghi, E; Tedeschi, A; Tufano, MA, 2015)
"Psoriasis is a chronic inflammatory skin disease affecting 2-5% of the population worldwide and it severely affects patient quality of life."( Du, L; Jin, Y; Kang, H; Li, M; Zhang, B; Zhang, X, 2015)
"Psoriasis is a chronic inflammatory skin disorder that is accompanied by an imbalance between the proliferation and differentiation of keratinocytes."( Fukami, K; Kanemaru, K; Matsuyuki, A; Nakamura, Y, 2015)
"Severe psoriasis is a systemic inflammatory disease involving major arteries and internal organs."( Kang, SY; Kim, SA; Lee, WW; Park, GY; Youn, SW, 2015)
"People with psoriasis are at higher cardiovascular risk."( Azzaretto, L; Campanati, A; Consales, V; Ganzetti, G; Giannoni, M; Giuliodori, K; Guanciarossa, F; Liberati, G; Offidani, A; Postacchini, V; Vichi, S, 2015)
"Plaque-type psoriasis is a chronic inflammatory skin disorder associated with chemoattractants driving neutrophils into the epidermis."( Flagler, ND; Janardhan, KS; King, D; Myers, P; Petranka, JG; Putney, JW; Steinckwich, N, 2015)
"Inverse psoriasis is clinically defined by chronic inflammatory lesions in intertrigineous areas."( Reich, K; Weisenseel, P, 2015)
"Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the world population and is mainly characterized by epidermal hyperplasia, scaling, and erythema."( Dejager, L; Grine, L; Libert, C; Vandenbroucke, RE, 2015)
"Psoriasis is a common, disfiguring and stigmatizing skin disease associated with impaired quality of life."( Aimetti, M; Ercoli, E; Manavella, V; Romano, F, 2015)
"Plaque psoriasis is a debilitating skin condition that affects approximately 2% of the adult population and for which there is currently no cure."( Buonanno, M; Papp, KA; Pariser, D; Tan, H; Tyring, SK; Valdez, H; Valenzuela, F; Wang, J; Wolk, R, 2015)
"Psoriasis is a disease of both localized and systemic low-grade inflammation."( Jessen, N; Kjær, TN; Pedersen, SB; Stenderup, K; Thorsen, K, 2015)
"Psoriasis is a chronic inflammatory skin disease expressing immune and hyperproliferative features."( Barreira, SM; Cabrini, DA; Carrenho, LZ; Dietrich, M; Duarte, ME; Ducatti, DR; Gomes Junior, R; Gonçalves, AG; Moreira, CG; Noseda, MD; Otuki, MF; Paludo, K; Vandresen, CC, 2015)
"Psoriasis is a common chronic skin disease that can also affect the mucous membranes and joints."( Abdel Raheem, HM; Abozaid, NA; Ezzat, MA; Nagui, NA; Rashed, LA, 2016)
"Psoriasis is a chronic autoimmune human skin disorder that is characterized by excessive proliferation of keratinocytes, scaly plaques, severe inflammation and erythema."( Arora, N; Pandey-Rai, S; Shah, K, 2016)
"Psoriasis is a common, immune-mediated inflammatory skin disease characterized by red, heavily scaled plaques."( Broadhurst, D; Dunn, WB; Goodacre, R; Griffiths, CE; Hollywood, KA; Winder, CL; Xu, Y, 2015)
"Guttate psoriasis is frequently associated with a preceding pharyngeal or perianal streptococcal infection in children."( Hernandez, M; Simms-Cendan, J; Zendell, K, 2015)
"Psoriasis is a chronic, inflammatory skin disease involving both environmental and genetic factors."( Chen, F; Chen, Y; Cheng, L; Hao, F; Niu, J; Qian, T; Shi, X; Song, Z; Wang, H; Yan, H; Zhai, Z; Zhang, D; Zhang, N; Zhong, B, 2015)
"Psoriasis is a chronic inflammatory skin condition characterized by well-circumscribed erythematous plaques with thick silvery scale."( Alavi, A; Bakshi, A; Gelfand, JM; Gholami, S; Takeshita, J, 2015)
"Psoriasis is a systemic immune-mediated chronic inflammatory disease."( Batycka-Baran, A; Hattinger, E; Prinz, JC; Ruzicka, T; Summer, B; Szepietowski, JC; Thomas, P; Wolf, R; Zack Howard, OM; Zwicker, S, 2015)
"Psoriasis is a common inflammatory skin disease of undetermined etiology and poor prognosis."( Ding, Y; Gao, Y; Yi, X; Zhou, J, 2015)
"Psoriasis is characterized by the unregulated proliferation of epidermal keratinocytes and increased expression of proinflammatory mediators in the skin."( Chen, ML; Chen, X; He, HL; Li, D; Yao, MZ, 2015)
"Psoriasis is a common chronic skin disease characterized by epidermal hyperplasia and inflammation."( Chen, X; Huo, R; Li, H; Li, N; Shen, B; Shen, Z; Sun, Y; Wang, B; Wu, P; Zhai, T; Zhang, J; Zhou, Z, 2015)
"Psoriasis is a chronic immune-mediated disorder that can be triggered by environmental changes, illness, smoking, or medications."( Bongiorno, MA; Meyerle, JH; Rivard, SSC, 2015)
"Psoriasis is a chronic inflammatory skin disease characterized by excessive proliferation and abnormal keratinocyte development, in which T helper type 17 cells and signal transducer and activator of transcription 3 (STAT3) activation have pivotal roles."( Aihara, M; Komitsu, N; Watanabe, T; Watanabe, Y; Yamaguchi, Y, 2015)
"Psoriasis is an inflammatory disease in which joints involvement may be insidious and difficult to detect."( Bartosińska, J; Chodorowska, G; Juszkiewicz-Borowiec, M; Kowal, M; Michalak-Stoma, A, 2015)
"Psoriasis is a chronic inflammatory disease with a well-documented negative effect on the quality of life of affected patients."( Bangsgaard, N; Rørbye, C; Skov, L, 2015)
"Psoriasis is one of the most common skin disorders characterized by erythematous plaques that result from hyperproliferative keratinocytes and infiltration of inflammatory leukocytes into dermis and epidermis."( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Al-Hosaini, KA; Al-Sharary, SD; Ansari, MA; Attia, SM; El-Sherbeeny, AM; Nadeem, A; Siddiqui, N; Zoheir, KM, 2015)
"Psoriasis is a chronic immune-mediated inflammatory condition that affects 2-3% of the population."( Beroukhim, K; Danesh, MJ; Koo, J; Levin, E; Nguyen, C, 2015)
"Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines."( Andrys, C; Borska, L; Fiala, Z; Hamakova, K; Kondelkova, K; Krejsek, J; Kremlacek, J; Rehacek, V; Rendarova, S, 2015)
"Psoriasis is increasingly recognised as a skin disease with far-reaching systemic effects, associated with a high prevalence of comorbid disease such as cardiometabolic dysfunction, shifting the focus from a single organ disease confined to the skin to a systemic inflammatory condition."( Gooren, L; Haider, A; Saad, F, 2016)
"Psoriasis is a chronic inflammatory skin disorder which can impair general routine activities and has been closely related to poor quality of life."( Albuquerque, RG; Andersen, ML; Hirotsu, C; Nogueira, H; Tomimori, J; Tufik, S, 2015)
"Psoriasis is a common chronic inflammatory skin disease."( Arias-Santiago, S; García-Serrano, JL; González Gallardo, MD; Gonzalez-Andrades, M; McAlinden, C, 2017)
"Psoriasis is a chronic inflammatory skin disease characterized by dysregulation of the immune system and release of pro-inflammatory mediators."( Bianchi, L; Buonomo, O; Chimenti, MS; Chimenti, S; Chiricozzi, A; Garofalo, V; Gramiccia, T; Perricone, R; Saraceno, R, 2015)
"Psoriasis is a chronic inflammatory skin condition that can markedly reduce life quality."( Abbott, R; Atwan, A; Bauer, A; Ingram, JR; Kelson, MJ; Pickles, T; Piguet, V, 2015)
"Psoriasis is a systemic inflammatory disease."( Armstrong, AW; Blauvelt, A; Krueger, GG, 2015)
"Palmoplantar psoriasis is a chronic debilitating type of psoriasis."( Klufas, DM; Strober, BE; Wald, JM, 2015)
"Psoriasis is a chronic inflammatory skin disease, characterized by hyperproliferation of keratinocytes and by skin infiltration of activated T cells."( D'Amico, F; Gangemi, P; Granata, M; Longo, V; Mazzarino, MC; Mosca, A; Pettinato, M; Rossi, GA; Skarmoutsou, E; Trovato, C, 2015)
"Psoriasis is a chronic inflammatory disease associated with several comorbidities, including depression."( da Silva Souza, C; Godoy, AL; Lanchote, VL; Rocha, A, 2016)
"Psoriasis is a chronic inflammatory skin disease and topical therapy remains a key role for treatment."( Chen, CC; Fang, JY; Kao, HC; Lin, YK; Yang, SH, 2015)
"Psoriasis is an inflammatory skin disease affecting ∼2% of the world's population, but the aetiology remains incompletely understood."( Abbatiello, B; Ajami, NJ; Belkaid, Y; Chen, Q; Chen, W; Chen, ZJ; Chia, C; Jiao, X; Kasagi, S; Konkel, JE; Nakatsukasa, H; Petrosino, JF; Smith, DP; Wu, R; Zanvit, P; Zhang, D, 2015)
"Psoriasis is a common immune-mediated, chronic, inflammatory skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes and infiltration of inflammatory cells."( Bertelsen, T; Hailfinger, S; Iversen, L; Johansen, C; Lorscheid, S; Mose, M; Ommen, P; Schulze-Osthoff, K; Vinter, H, 2015)
"Pustular psoriasis is an uncommon psoriasis variant, clinically characterized as small sterile pustules on an erythematous base."( Divito, SJ; Enamandram, M; Merola, JF; Sheu, JS, 2016)
"Psoriasis is a chronic inflammatory skin disease of unknown etiology."( Bajenoff, M; Chelbi, R; Dalod, M; Henri, S; Jorquera, A; Malissen, B; Malosse, C; Tamoutounour, S; Terhorst, D; Wohn, C, 2015)
"Psoriasis is a T-cell mediated chronic systemic inflammatory skin disease."( Ananthanarayanan, PH; Chandrashekar, L; Indhumathi, S; Negi, VS; Rajappa, M; Thappa, DM, 2016)
"Chronic plaque psoriasis is an inflammatory skin disease affecting 2-3% of the world population."( Katare, OP; Raza, K; Sharma, G; Singh, B; Wadhwa, S, 2016)
"Psoriasis is a chronic inflammatory skin disease characterized by a relapsing-remitting disease course and correlated with increased expression of proinflammatory cytokines, such as tumor necrosis factor (TNF) and interleukin 22 (IL22)."( Charpin-El Hamri, G; Fussenegger, M; Geering, B; Schukur, L, 2015)
"Psoriasis is a skin disease associated with hyperproliferation and abnormal differentiation of keratinocytes."( Amnuaikit, T; Chorachoo, J; Musthafa, KS; Saeloh, D; Sretrirutchai, S; Srichana, T; Voravuthikunchai, SP, 2016)
"Psoriasis is a common, chronic, inflammatory skin disease."( Cannizzaro, MV; Caposiena, D; Chimenti, S; Chiricozzi, A; Garofalo, V; Saraceno, R, 2016)
"Psoriasis is a T-helper (Th)1/Th17-mediated, chronic inflammatory dermatosis related to metabolic syndromes and serum LCN2 levels are elevated in psoriatic patients."( Fukusato, T; Hau, CS; Kanda, N; Sato, S; Shibata, S; Tada, Y; Uozaki, H; Watanabe, S, 2016)
"Psoriasis is a common inflammatory disease with significant comorbidities, whose management can be challenging given the variety of treatment options."( Aldredge, L; Armstrong, AW; Yamauchi, PS, 2016)
"Psoriasis is a one of the most common chronic skin diseases, which affects 0."( An, J; Dong, Y; Huo, J; Li, Z; Ren, J, 2016)
"Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities."( Golusin, Z; Jovanović, M; Magda, N; Matić, M; Petrović, A; Stojanović, S, 2015)
"Psoriasis is a chronic skin disease of unknown aetiology but increasing evidence suggests that cutaneous angiogenesis plays an important role."( Liu, JH; Luo, DQ; Wu, HH; Xie, WL; Zhao, YK, 2016)
"Psoriasis is a chronic inflammatory skin disease with genetic and environmental factors having an important role in its aetiology."( Ananthanarayanan, PH; Chandrashekar, L; Indhumathi, S; Negi, VS; Rajappa, M; Thappa, DM, 2015)
"Psoriasis is a chronic immune-mediated inflammatory skin disease with both genetic and environmental factors contributing to its pathogenesis."( Corbelli, E; Fargnoli, MC; Gaudio, E; Pellegrini, C; Peris, K; Sferra, R; Vetuschi, A, 2014)
"Psoriasis is associated with increased cardiovascular disease in adults, but the risk profile of children with psoriasis remains to be fully characterized."( Admani, S; Eichenfield, LF; Joshi, AA; Mehta, NN; Natarajan, B; Playford, MP; Tom, WL, 2016)
"Moderate to severe psoriasis is a systemic inflammatory disease associated with insulin resistance, obesity and type 2 diabetes (T2DM)."( Ahern, TB; Hughes, R; Kelly, G; Kirby, B; Lynch, M; O'Shea, D; Sweeney, C; Timoney, I; Tobin, AM, 2016)
"Chronic plaque psoriasis is partially mediated by elevation of proinflammatory cytokines, including several within the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway."( Bissonnette, R; Chen, X; Fidelus-Gort, R; Flores, R; Jackson, S; Luchi, M; Menter, A; Newton, R; Scherle, P; Yeleswaram, S; Zhang, H, 2016)
"Psoriasis is a chronic inflammatory skin disease characterized by altered proliferation and differentiation of keratinocytes as well as infiltration of immune cells."( Malik, G; Mittal, S; Narasimhan, A; Saini, N; Sardana, K; Varshney, P, 2016)
"Psoriasis is a multi-factorial heritable prototypical immune-mediated inflammatory disease, characterized by hyperproliferation of keratinocytes in the affected skin."( Ananthanarayanan, PH; Chandrashekar, L; Indhumathi, S; Negi, VS; Rajappa, M; Thappa, DM, 2016)
"Plaque psoriasis is a chronic and often debilitating skin disorder and proinflammatory cytokines are known to play a key role in the disease process."( Disch, D; Gaich, C; Janes, JM; Macias, W; Menter, MA; Papp, KA; Raman, M; Schlichting, DE; Zhang, X, 2016)
"Psoriasis is one of the most common chronic inflammatory diseases of the skin."( Ban, CY; Choi, YJ; Kim, HP; Kim, J; Kim, JH; Kim, SC; Kim, SE; Kim, TG; Lee, BH; Park, J; Park, SH; Shin, EC; Song, MY; Sung, YC, 2016)
"Psoriasis is a multifactorial skin disease that inconveniences many patients."( Bao, YL; Huang, YX; Li, WL; Li, YX; Song, ZB; Sun, LG; Wang, Q; Yang, XG; Yu, CL; Zhang, WJ, 2016)
"Psoriasis is a chronic inflammatory skin disorder involving marked immunological changes."( Birault, V; Brusq, JM; Bui, T; Cote-Sierra, J; Hofland, H; Jetten, AM; Millerman, E; Neil, J; Nicodeme, E; Peredo, CE; Rickard, D; Smith, SH; Takeda, Y; Therrien, JP; Viviani, F, 2016)
"Psoriasis is an inflammatory skin condition that affects approximately 2 % of people worldwide."( Lim, HW; Mehta, D, 2016)
"Psoriasis is a chronic autoimmune disease of undefined etiology that involves dysregulated interplay between immune cells and keratinocytes."( Chao, YH; Chen, DY; Chen, HH; Chung, TW; Li, YR; Lin, CC; Yang, DH, 2016)
"Psoriasis is a chronic inflammatory immune-mediated autoimmune skin disorder."( Chang, KT; Choo, YK; Kim, CH; Kim, JS; Kim, SU; Lee, JM; Yoo, JK, 2016)
"Psoriasis is a common skin disease accompanied by chronic inflammation."( Cho, D; Houh, Y; Kim, KE; Park, HJ, 2016)
"Psoriasis is a common skin disorder that is associated with impairments in quality of life (QOL) and psychological distress."( Dogra, S; Gupta, S; Handa, S; Narang, T; Singh, SM; Verma, AK, 2016)
"Annular pustular psoriasis is not typically observed in cases of arthritis."( Mikage, H; Nagafuchi, H; Ozaki, S; Watanabe, K, 2016)
"Nail psoriasis is challenging to treat."( Madan, R; McDermott, L; Rupani, R; Siegel, D, 2016)
"Psoriasis is a chronic skin disease that affects approximately 2% of the world's population."( Jia, W; Li, J; Li, K; Li, Z; Xiao, T; Yang, W; Zhang, P, 2016)
"Psoriasis is a common skin disorder that causes skin inflammation."( Morimura, S; Oka, T; Sato, S; Sugaya, M, 2016)
"Psoriasis is characterized by resistance to infections, which is regulated by antimicrobial proteins."( Cao, T; Fang, H; Hu, J; Jin, L; Li, B; Shao, S; Wang, G; Zhang, J; Zhang, Y, 2016)
"Psoriasis is an autoimmune skin disease that is associated with aberrant activity of immune cells and keratinocytes."( Hahn, M; Hövelmeyer, N; Karbach, SH; Klebow, S; Nikoalev, A; Waisman, A; Wunderlich, FT, 2016)
"Psoriasis is a chronic and recurrent inflammatory skin disease."( Chen, JK; Hong, YY; Qin, WL; Sun, LY; Wang, TC; Zhou, DM; Zhou, R; Zhou, ZX, 2016)
"Psoriasis is a chronic disease that has a substantial effect on quality of life of patients and often needs long-term treatment."( Stein Gold, LF, 2016)
"Psoriasis is a common, chronic, recurrent, immune-mediated disorder of the skin and joints."( Chantzaras, A; Kontochristopoulos, G; Kouris, A; Petridis, A; Yfantopoulos, J, 2016)
"Psoriasis is a potential complication in kidney recipients that may recur when belatacept is used and/or tacrolimus is withdrawn as it could have happened in the first patient."( Cicora, F; Roberti, J, 2016)
"Psoriasis is a chronic inflammatory skin disease with excessive activation of toll-like receptors (TLRs), which play important roles in developing psoriasis."( Shao, F; Sun, Y; Tan, T; Tan, Y; Wu, X; Xu, Q, 2016)
"Psoriasis is a chronic skin disease associated with increased morbidity and mortality."( Smith, D, 2017)
"Psoriasis is one of the most common immune-mediated chronic inflammatory skin disorders, characterized by hyperproliferation of keratinocytes, dilation and growth of dermal capillary vasculature, and cellular infiltration of T cells, dendritic cells (DCs), and neutrophils."( Cao, N; Chen, T; Fu, LX; Lu, YH; Yin, B; Zhang, LW; Zhou, PM, 2016)
"Psoriasis is a common chronic skin condition characterized by excessive inflammation and aberrant epidermal proliferation."( Chong, HT; Cowin, AJ; Ibbetson, J; Kopecki, Z; Sidhu, S; Yang, GN, 2017)
"Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the population."( Bianchi, L; Chimenti, S; Chiricozzi, A; Del Duca, E; Romanelli, M; Saraceno, R, 2016)
"Psoriasis is one of the most common inflammatory skin disorders, affecting 3% of the general population."( An, J; Dong, Y; Huo, J; Li, T; Li, Z, 2016)
"Psoriasis is a chronic inflammatory skin condition characterised by the formation of red scaly plaques on the skin."( Al-Mutairi, N; Bachelez, H; Gulliver, S; Gulliver, WP; Randell, S; Young, HM, 2016)
"Psoriasis is a chronic inflammatory skin disease in which Th17 cells play a crucial role."( Hercogová, J; Hornová, M; Hudcovic, T; Jůzlová, K; Klimešová, K; Kostovčík, M; Kverka, M; Málková, J; Novosádová, I; Rossmann, P; Stehlíková, Z; Štepánková, R; Tlaskalová-Hogenová, H; Zákostelská, Z, 2016)
"Psoriasis is a chronic inflammatory skin disease characterized by hyper proliferation of keratinocytes."( Dayalan, H; Elango, T; Ethiraj, P; Gnanaraj, P; Subramanian, S; Thirupathi, A, 2017)
"Psoriasis is a chronic inflammatory disease of the skin and joints that may also have systemic inflammatory effects, including the development of cardiovascular disease (CVD)."( Cao, L; Cooper, KD; Debanne, SM; Feig, RL; Gilkeson, RC; Golden, JB; Grozdev, I; Kast, DR; Korman, NJ; McCormick, TS; Orringer, CE; Santilli, S; Ward, NL, 2016)
"Psoriasis is a common inflammatory skin disease characterized by T cell-mediated hyperproliferation of keratinocytes, increased angiogenesis and inflammation."( Li, R; Ma, H; Wang, J; Wang, M; Wang, X; Xiao, S; Zhou, J, 2016)
"Psoriasis is associated with obesity; patients with psoriasis have a higher incidence of obesity, and obese individuals have a higher risk of developing psoriasis."( Iversen, L; Johansen, C; Langkilde, A; Ommen, P; Rosada, C; Stenderup, K; Stjernholm, T, 2017)
"Psoriasis is a systemic inflammatory condition that is associated with a higher risk of cardiovascular (CV) disease."( Ahlehoff, O; Egeberg, A; Hansen, PR; Qureshi, AA; Robertson, D; Strober, BE; Tan, H; Valdez, H; Wolk, R; Wu, JJ, 2016)
"Psoriasis is thought to be initiated by abnormal interactions between cutaneous keratinocytes and systemic immune cells."( Cheng, L; Cui, X; Dai, L; Deng, H; Li, C; Li, J; Li, Y; Lin, Y; Liu, Y; Shi, G; Wang, F; Wang, H; Wang, Y; Wei, Y; Xiang, R; Yang, Q; Yang, Y; Yu, D; Zhang, J; Zhang, S; Zhang, X, 2016)
"Psoriasis is a chronic T-cell-mediated autoimmune disease, and FMS-like tyrosine kinase 3 (FLT3) has been considered as a potential molecular target for the treatment of psoriasis."( Chen, YC; Fang, Z; Huang, SZ; Ji, S; Li, GB; Li, LL; Ma, S; Niu, D; Wang, JH; Wang, LJ; Xiang, R; Xiong, Y; Yang, LL; Yang, SY; Zhang, G; Zhong, JM, 2016)
"Psoriasis is a chronic auto-immune inflammation disease with skin lesions and abnormal keratinocyte proliferation."( Liu, J; Luo, H; OuYang, Q; Pan, Y; Xuan, C, 2016)
"Inverse psoriasis is characterized by the development of erythematous shiny plaques at intertriginous areas of the body."( Arjona Aguilera, C; Espinosa Rosso, R; Jiménez Gallo, D; Linares Barrios, M; Rojo Suárez, N, 2017)
"Psoriasis is an immune-mediated inflammatory skin disease with a strong genetic background in which activation of IL-17 signaling is central in the pathogenesis."( Li, D; Lohcharoenkal, W; Meisgen, F; Nikamo, P; Pivarcsi, A; Sonkoly, E; Srivastava, A; Ståhle, M; Xu Landén, N, 2017)
"Psoriasis is an inflammatory skin disease with or without joint involvement."( Cubillos, S; Norgauer, J, 2016)
"Psoriasis is a debilitating chronic inflammatory disease."( Ferris, LK; Ilkovitch, D, 2016)
"Psoriasis is a common chronic inflammatory and immune-mediated skin disease."( Bertelsen, T; Boye Kjellerup, R; Iversen, L; Johansen, C; Ljungberg, C, 2017)
"Psoriasis is a common chronic inflammatory skin disease observed in about 1-3% of the general population."( Reich, A; Szepietowski, JC, 2016)
"Psoriasis is a chronic inflammatory immune disease with undefined pathogenesis."( Fang, F; Liu, X; Mei, L; Wang, H; Zhang, S, 2016)
"Scalp psoriasis is commonly the initial presentation of psoriasis, and almost 80 % of patients with psoriasis will eventually experience it."( Tsai, TF; Wang, TS, 2017)
"Psoriasis is a chronic disease, and long-term adherence is an even bigger problem."( Alinia, H; Anderson, KL; Bahrami, N; Farhangian, ME; Feldman, SR; Huang, KE; Jaros, SC; Moradi Tuchayi, S; Richardson, IM; Sandoval, LF; Smith, JA, 2017)
"Psoriasis is a chronic inflammatory skin disease with a clear genetic contribution, characterized by keratinocyte proliferation and immune cell infiltration."( Finkelstein, D; Gangwar, R; Gingras, S; Häcker, H; Ippagunta, SK; Pelletier, S; Redecke, V; Vogel, P, 2016)
"Psoriasis is an autoimmune skin disorder characterized by hyper proliferation and poor differentiation of keratinocytes."( Domb, AJ; Doppalapudi, S; Jain, A; Khan, W, 2016)
"Plaque psoriasis is the most common phenotype."( Choon, SE; Nalini, MN; Ngim, CF; Premaa, S; Tey, KW, 2016)
"Psoriasis is associated with cardiovascular disease; it has been proposed that increased cardiovascular risk is caused by low-grade systemic inflammation involving organs and tissues other than the skin and joints."( Egeberg, A; Gormsen, LC; Hjuler, KF; Iversen, L; Nielsen, J; Vendelbo, MH, 2017)
"Psoriasis is one of the most common immune-mediated chronic inflammatory skin disorders and is accompanied by erythematous scaly plaques."( Aoki, M; Furue, Y; Fusamae, Y; Imura, C; Okuda, T; Oshima, I; Shichijo, M; Suzuki, M; Tsujii, K; Ueyama, A; Yamamoto, M; Yasui, K, 2017)
"Psoriasis is a complex multifactorial chronic inflammatory skin disorder involving both genetic and environmental susceptibility factors."( Chandra, A; Chatterjee, G; Chatterjee, R; Ghosh, S; Senapati, S, 2017)
"Psoriasis is an autoimmune skin disease, in which keratinocytes play a crucial pathogenic role."( Cao, T; Gao, T; Ge, R; Guo, S; Li, B; Li, C; Liu, L; Wang, G; Wang, H; Zhang, W, 2017)
"Psoriasis is associated with metabolic syndrome and cardiovascular disease."( Bacharewicz-Szczerbicka, J; Baran, A; Flisiak, I; Myśliwiec, H; Świderska, M, 2017)
"Psoriasis is associated with increased risk for cardiovascular disease."( Cloutier, M; Dea, K; Guérin, A; Mulani, P; Sundaram, M; Wu, JJ, 2017)
"Psoriasis is a chronic, immune-mediated inflammatory disorder with a significant negative impact on quality of life."( Bang, B; Lebwohl, M; Paul, C, 2017)
"Psoriasis is a high-incident T-cell-mediated autoimmune disease mainly affecting the skin."( Chen, W; Fei, C; Gong, Y; Shi, Y; Tong, Y; Wang, X; Wang, Y; Xu, H; Yu, Q; Zhang, X, 2017)
"Psoriasis is known today as a T‑cell-mediated autoimmunological systemic disease."( Fischer, M; Gilbrich, F; Philipp, S; Wohlrab, J; Wolff, L, 2017)
"Psoriasis is a chronic-relapsing skin disorder which requires long-term treatments."( Calzavara Pinton, P; Cicchetti, A; Cristaudo, A; Girolomoni, G, 2018)
"Psoriasis is known to be associated with an up-regulation of T-helper (Th)-1 & Th-17 cytokines and a relative down-regulation of Th-2 and T-regulatory (T-reg) cytokines."( Ananthanarayanan, PH; Chandrashekar, L; Indhumathi, S; Negi, VS; Rajappa, M; Thappa, DM, 2017)
"Psoriasis is a chronic inflammatory skin disease with a prevalence of 2-3 %."( Florencia, EF; Hekking-Weijma, IM; Onderdijk, AJ; Prens, EP, 2017)
"Psoriasis is a chronic, inflammatory and immune-mediated disease."( Akbulak, O; Akdeniz, N; Demirkan, S; Karadag, AS; Oguztuzun, S; Ozkanli, S; Ozlu, E; Uzuncakmak, TK, 2017)
"Psoriasis is a chronic relapsing immune mediated disorder of the skin."( Arumugam, M; Sundarrajan, S, 2017)
"Psoriasis is a chronic skin disease also affecting other sites such as joints."( Norooznezhad, AH; Norooznezhad, F, 2017)
"Psoriasis is a common skin condition, affecting 1."( Lyon, CC; Marshall, C; Woodmansey, S, 2017)
"Peristomal psoriasis is common but potentially under-recognized."( Lyon, CC; Marshall, C; Woodmansey, S, 2017)
"Psoriasis is a chronic inflammatory skin disease mediated by dysregulated auto-reactive immune system."( Arita, K; Hirai, M; Kurebayashi, Y; Mori, H; Yamaguchi, T, 2016)
"Psoriasis is a chronic inflammatory skin disease characterized by erythematous plaques on extensor surfaces, scalp, and back."( Alikhan, A; Vangipuram, R, 2017)
"

BACKGROUND: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression."

( Alexander, BJ; Gold, LS; Lebwohl, MG; Pariser, DM; Pillai, R; Sugarman, JL, 2017)
"Psoriasis is a chronic, recurrent, inflammatory dermatosis accompanied by excessive activation of Toll‑like receptors (TLRs) in dendritic cells (DCs), which are primarily responsible for initiating an immune response."( Di, T; Li, N; Li, P; Lin, Y; Meng, Y; Wang, M; Wang, Y; Xie, X; Xu, X; Zhai, Y; Zhao, J, 2017)
"Psoriasis is an immune-mediated skin disorder, which is triggered by the aberrant activation of dendritic cells in skin."( Chen, X; Cun, D; Liu, Z; Sun, L; Tong, HHY; Wang, L; Wang, R; Yan, R; Zheng, Y, 2017)
"Psoriasis is a common autoimmune skin disease."( Eding, CB; Enerbäck, C, 2017)
"Psoriasis is a chronic, multisystem inflammatory disease with predominantly skin and joint involvement."( Jerome, D; Kim, WB; Yeung, J, 2017)
"Psoriasis is a chronic autoimmune disease that cannot be cured."( Basri, M; Fard Masoumi, HR; Musa, SH; Salim, N; Shamsudin, N, 2017)
"Psoriasis is a refractory inflammatory disease, however, its pathophysiology is still not fully understood."( Arito, M; Kato, T; Kurokawa, MS; Matsuura, T; Nagai, K; Okamoto, K; Omoteyama, K; Sato, M; Sato, T; Soma, Y; Suematsu, N, 2017)
"Psoriasis is characterized by hyperproliferation and inflammation."( Chen, Q; Chi, M; Deng, X; Leavesley, D; Shi, H; Xie, N; Xie, Y; Yang, Y; Zhang, H; Zhou, H, 2017)
"Psoriasis is a chronic and persistent inflammatory skin disease seriously affecting the quality of human life."( Bai, R; Bi, Z; Dong, Y; Dou, R; Li, D; Liu, Z; Mao, C; Su, W; Xiangfei, D; Yang, P; Yang, Y; Yuan, X, 2017)
"Psoriasis is a common chronic inflammatory skin disease that manifests as scaly erythematous plaques as a consequence of keratinocyte hyperproliferation and inflammation."( Ip, W; Kirchhof, MG, 2017)
"Psoriasis is a chronic inflammatory skin disease that is associated with increased vascular inflammation by 18fluorodeoxyglucose positron emission tomography/computed tomography in vivo and future cardiovascular events."( Aberra, TM; Ahlman, MA; Baumer, Y; Chaturvedi, A; Chung, JH; Dey, AK; Ehrlich, A; Gelfand, JM; Gerson, E; Green, LJ; Harrington, CL; Joshi, AA; Kabbany, MT; Lerman, JB; Lockshin, BN; Mehta, NN; Natarajan, B; Ng, Q; Playford, MP; Prussick, RB; Rivers, JP; Rodante, JA; Sanda, GE; Silverman, JI; Sorokin, AV; Teague, HL, 2017)
"Psoriasis is associated with dyslipidemia and metabolic syndrome, and has been linked to an increased cardiovascular risk."( DeMicco, DA; Fayyad, R; Laskey, R; Ports, WC; Wolk, R, 2017)
"Psoriasis is a chronic inflammatory skin disorder, characterised by epidermal hyperplasia (acanthosis) and leukocyte infiltration of the skin."( Fuller, SJ; Geraghty, NJ; Mansfield, KJ; Sluyter, R; Watson, D, 2017)
"Psoriasis is a chronic immune-mediated disease associated with several co-morbidities and negative impacts on a patient's quality of life."( Puig, L; Torres, T, 2018)
"Psoriasis is one of the most common immune-mediated chronic inflammatory skin disorders."( Chen, T; Fu, LX; Guo, ZP; Liu, XY; Wu, YB; Zhang, LW, 2017)
"Psoriasis is a common chronic skin disease characterized by epidermal hyperplasia and inflammation."( Huo, R; Li, H; Li, N; Shen, B; Shen, Z; Wu, P; Xu, H, 2017)
"Psoriasis is a long-term disease, and improving adherence in the short time could improve patient's adherence to treatment in long time."( Feldman, SR; Firooz, A; Hasanzadeh, H; Rajabi-Estarabadi, A; Taheri, A, 2018)
"Psoriasis is a common chronic immune-mediated skin disease which has a significant impact on patients' quality of life, and is associated with numerous comorbidities (i."( Frieder, J; Kivelevitch, D; Menter, A, 2017)
"Psoriasis is an inflammatory skin disease with aberrant keratinocyte proliferation, presumably as a result of immune cell activation."( Brück, J; Carevic, M; Eberle, FC; Fehrenbacher, B; Ghoreschi, K; Holstein, J; Müller-Hermelink, E; Schäfer, I; Schaller, M; Schittek, B, 2017)
"Psoriasis is a skin disease with also systemic involvement: its impact on the eye is not well established and often clinically underestimated."( Aragona, E; Aragona, P; Cannavò, SP; Giuffrida, R; Interdonato, A; Postorino, EI; Puzzolo, D; Rania, L, 2018)
"Psoriasis is a common chronic dermatosis characterized by keratinocyte hyperproliferation accompanied by inflammatory reactions."( Liu, Y; Meng, L; Tan, X; Wei, G; Xu, Q; Zhang, C, 2017)
"Psoriasis is considered to be a systemic disease of immune dysfunction."( M, R; Mishra, A; P, R; Prabhu, S; Sivaprakasam, TO; Varma, SR, 2017)
"Psoriasis is a chronic inflammatory skin disease that affects 2-3% of the global population, and there is still no known possibility of a cure."( Chen, H; Duan, X; Gan, L; He, M; Hu, F; Liu, X; Ming, Z; Poorun, D; Wang, X; Xu, J; Zhang, S; Zhu, K, 2017)
"Psoriasis is a chronic inflammatory disease of the skin."( Ananthanarayanan, PH; Chandrasekaran, A; Chandrashekar, L; Rajappa, M; Satheesh, S; Sudhesan, A; Thappa, DM, 2017)
"Psoriasis is a chronic immune-mediated dermatologic disorder affecting approximately 2% of the general population."( Meyerle, J; Rosenberg, A, 2017)
"Psoriasis is often accompanied by itch, but the mechanisms behind this symptom remain elusive."( Akiyama, T; Jensen, LE; Sakai, K; Sanders, KM; Yanushefski, KM; Yosipovitch, G; Youssef, MR, 2017)
"Psoriasis is associated with risk of cardiovascular (CV) disease (CVD) and a major adverse CV event (MACE)."( Ahlman, MA; Egeberg, A; Gelfand, JM; Gislason, GH; Joshi, AA; Lerman, JB; Mallbris, L; Mehta, NN; Rodante, J; Skov, L; Wu, JJ, 2017)
"Psoriasis is an inflammatory skin disease with increased neovascularization, keratinocyte hyperproliferation, a proinflammatory cytokine milieu, and immune cell infiltration."( Brunner, SM; Ebner, S; Holub, BS; Kofler, B; Koller, A; Lang, R; Reitsamer, HA; Schwarzenbacher, D; Sternberg, F; Stockinger, J; Trost, A; Vidali, S, 2018)
"Psoriasis is a chronic inflammatory skin disease affecting 2."( Arbiser, JL; Biedermann, T; Bonner, MY; Fritz, Y; Gilbert, LC; Karlsson, I; Lewis, MJ; Michaels, K; Nowak, R; Rao, S; Skabytska, Y; Ward, NL; Yusuf, N, 2017)
"Psoriasis is a chronic inflammatory autoimmune disease that can be initiated by excessive activation of endosomal toll-like receptors (TLRs), particularly TLR7, TLR8, and TLR9."( Chuang, TH; Hsu, LC; Lai, CY; Lin, KI; Su, YW, 2017)
"Psoriasis is a chronic inflammatory skin disease that affects about 1%-3% of the world's population."( Abdelaziz, EZ; Bayomy, NA; Okasha, EF, 2018)
"Psoriasis is a chronic inflammatory skin disease severely affecting patients' physical and psychological well-being."( Dang, E; Hu, L; Jiang, M; Li, B; Wang, G; Zhang, J, 2017)
"Psoriasis is a common, an inflammatory skin disease."( Aleksiejczuk, P; Borawska, MH; Niczyporuk, M; Ostrowska, J; Socha, K; Soroczyńska, J; Wacewicz, M, 2017)
"Psoriasis is a chronic inflammatory skin disorder of unknown etiology."( Gao, Q; Liu, JH; Luo, DQ; Wang, F; Wu, HH; Zhao, YK, 2018)
"Psoriasis is a chronic inflammatory skin disease affecting 2%-3% of the population."( Bottoni, U; De Carvalho, N; Del Duca, E; Farnetani, F; Nisticò, SP; Pellacani, G, 2017)
"Psoriasis is an immunodysregulatory inflammatory disease associated with comorbidities affecting quality of life."( Greenberg, JD; Guo, N; Holmgren, SH; Karki, C; Lebwohl, M; Mason, M; Strober, B, 2018)
"Psoriasis is an independent risk factor for cardiovascular disease; however, the underlying mechanisms are not fully understood."( Alba, BK; Alexander, LM; Ferguson, SB; Greaney, JL, 2018)
"Palmoplantar psoriasis is a variant of psoriasis vulgaris which can severely impair quality of life."( Barber, K; Bissonnette, R; Bukhalo, M; Delorme, I; Fowler, JF; Gagné-Henley, A; Gooderham, M; Haydey, R; Jenkin, P; Landells, I; Lynde, CW; Pariser, DM; Poulin, Y; Rosoph, LA, 2018)
"Psoriasis is a common and chronic inflammatory disease of the skin."( Hu, SC; Lan, CE, 2017)
"Psoriasis is a chronic inflammatory skin disorder."( Chen, FY; Cheng, HM; Ho, TY; Hsiang, CY; Li, CC; Liao, YF; Lo, HY, 2017)
"Psoriasis is a T-cell-mediated skin disease with autoimmune nature that is generally not observed in animals, this lack of a relevant experimental animal model of psoriasis has hindered the investigation of pathogenesis of disease."( Bahrami, G; Faridi-Majidi, R; Ghahramani, MH; Izadi, B; Madani, SH; Nemati, H; Tavoosidana, G, 2017)
"Psoriasis is often treated with immunomodulatory therapies that can affect the immune response to common antigens."( Abramovits, W; Gardner, A; Kaur, M; Korman, N; Mukwaya, G; Rottinghaus, ST; Tan, H; Valdez, H; Winthrop, KL, 2018)
"Psoriasis is a common, chronic, immune-mediated disease associated with several comorbidities."( Azevedo, A; Torres, T, 2018)
"Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group."( Chen, Z; Shi, Y; Subedi, S; Yu, Q, 2018)
"Psoriasis is a chronic inflammatory skin disease whose pathogenesis is driven by multiple cytokine-mediated pathways."( Chiricozzi, A; Gualtieri, B; Panduri, S; Romanelli, M; Tonini, A, 2018)
"Psoriasis is an autoimmune skin disease characterized by keratinocyte hyperproliferation and chronic inflammation."( Patel, AB; Theoharides, TC; Tsilioni, I; Weng, Z, 2018)
"Psoriasis is a hyperproliferative inflammatory skin disease; therefore, it is highly likely that psoriatic skin lesions may transform into malignancies."( Cho, JW; Choe, MS; Jung, JW; Kim, SA; Kwon, JI; Ryu, YW, 2018)
"Psoriasis is a chronic inflammatory skin disorder that greatly affects the patient's quality of life."( Sun, Q; Wang, XL, 2017)
"Psoriasis is largely mediated by interleukin (IL)-23/T helper (Th) 17 axis, and IL-21 is a pleiotropic cytokine expressed by Th17 cells."( Kim, DS; Kim, HJ; Kim, SH; Kim, TG; Lee, M; Lee, MG; Park, JY, 2018)
"Psoriasis is an immune-mediated, inflammatory disease."( Goulis, DG; Kyriakou, A; Patsatsi, A; Sotiriadis, D, 2017)
"Psoriasis is a chronic inflammatory cutaneous disorder with undefined etiology and is characterized by abnormal cellular proliferation, angiogenesis, and inflammation."( Cai, SQ; Chen, JQ; Landeck, L; Li, W; Man, XY; Min, M; Wang, P; Yan, BX; Zheng, M, 2017)
"Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and differentiation."( Guo, W; Wang, G; Yang, L; Zhang, S, 2018)
"Psoriasis is a chronic inflammatory disease characterized by epidermal hyperplasia and increased T cell infiltration."( Chen, M; Chen, W; Chen, X; He, Y; Kuang, Y; Li, J; Liu, P; Su, J; Tao, J; Wang, H; Zhang, J; Zhao, S; Zhu, W, 2018)
"Psoriasis is a chronic inflammatory skin disease that accelerates atherosclerosis in humans and provides a compelling model to understand potential pathways linking these diseases."( Baumer, Y; Belur, AD; Bleck, CK; Dagur, PK; Dey, AK; Gelfand, JM; Goyal, A; Harrington, CL; Joshi, AA; Kruth, HS; Marinkovich, MP; Mehta, NN; Ng, Q; Playford, MP; Rodante, JA; Rose, SM; Sanda, GE; Silverman, JI; Sorokin, AV; Springer, DA; Teague, HL; Thomas, CL; Varghese, NJ; Winge, MC; Yu, ZX, 2018)
"Psoriasis is a chronic T-cell-mediated skin disease with marked social and economic burdens."( Barker, RN; Kotb, IS; Lewis, BJ; Ormerod, AD, 2018)
"Psoriasis is a systemic inflammatory disorder, associated with both physical and psychological burden, and can be the presenting feature of HIV infection."( Queirós, N; Torres, T, 2018)
"Psoriasis is a chronic auto-immune inflammation disease with skin lesions and abnormal keratinocyte proliferation."( Chen, X; Jia, XK; Kuang, YH; Liao, LQ; Liu, YK; Lu, Y; Qin, QS; Wu, LS; Zhou, XC; Zhu, W, 2018)
"Psoriasis is a chronic inflammatory skin disease, which requires long-term, safe and effective treatment."( Kokkalis, G; Papadavid, E; Rigopoulos, D; Rompoti, N; Theodoropoulos, K, 2018)
"Psoriasis is a chronic inflammatory skin disease characterized by red, scaly and raised plaques."( Chen, X; Ji, M; Jin, J; Lai, F; Wang, Y; Xue, N; Zhang, S; Zhang, X, 2018)
"Psoriasis is an immune-mediated inflammatory disease of the skin."( Saini, N; Varshney, P, 2018)
"Psoriasis is a commonly encountered chronic dermatological disease, presenting with inflammatory symptoms in patients."( Aboel-Fadl, DM; Fadel, M; Nasr, M; Nour El-Deen, F; Ramez, SA; Soliman, MM; Youness, ER, 2018)
"Psoriasis is one of the most common chronic skin diseases, affecting 1%-3% of the general population."( Gholam, K; Kravvas, G, 2018)
"Psoriasis is a chronic inflammatory skin disease characterized by erythema, skin hyperplasia, scales, and keratinocyte hyperproliferation."( Kainoh, M; Koga, Y; Takahashi, T, 2018)
"Psoriasis is a chronic inflammatory skin disorder associated with several comorbidities, including atherosclerosis."( Cardoso, RM; Hansen, PR; Madsen, M; Nielsen, LB; Pedersen, TX; van Eck, M, 2018)
"Psoriasis is a chronic inflammatory disease of the skin affecting approximately 2% of the world's population."( Berti, E; Damiani, G; Fiore, M; Leone, S; Maraolo, AE, 2018)
"Psoriasis is a common inflammatory condition found in 1-2% of the population."( Arbiser, JL; Elsey, J, 2018)
"Psoriasis is an autoimmune and recurrent chronic inflammatory skin disorder with a strong genetic basis."( Azizian, Z; Bahraini, P; Chalangari, R; Mansouri, P; Rajabi, M; Sarafian, G, 2018)
"Psoriasis is a chronic inflammatory skin disease with systemic manifestations and potential genetic etiology."( Chandrasekharan, UM; DiCorleto, PE; Harvey, J; Husni, ME; Lax, JE; Seifarth, FG; Tytell, M, 2018)
"Psoriasis is a common, chronic, inflammatory skin disease that affects 2%-4% of the global population."( Lai, R; Song, J; Xian, D; Xiong, X; Yang, L; Zhong, J, 2018)
"Psoriasis is a chronic, immune-mediated inflammatory skin disease with severe consequences for the whole organism."( Domingues, P; Gęgotek, A; Skrzydlewska, E; Wójcik, P; Wroński, A, 2018)
"Psoriasis is a chronic autoinflammatory skin disease."( An, H; Dong, C; Lai, Y; Lee, YH; Liu, K; Lu, H; Shi, Y; Wang, X; Wu, Y; Xu, M; Zhang, J, 2018)
"Psoriasis is a chronic skin disease associated with psychiatric co-morbidities, especially depression."( Han, J; Kim, BS; Kim, GW; Kim, HS; Kim, MB; Kim, SJ; Ko, HC; Pak, K; Park, MY, 2018)
"Psoriasis is a recurrent hyper-proliferative skin disease which is often associated with free radical generation, abnormal lipid metabolism and increased inflammatory secretion that induce cardiovascular risk in these patients."( Aggarwal, A; Arora, VK; Asha, K; Sharma, SB; Singal, A, 2017)
"Psoriasis is a multi-systemic chronic inflammatory skin disease."( Alhan, A; Özdemir, ED; Tuğrul Ayanoğlu, B; Türkoğlu, O, 2018)
"Psoriasis is a common chronic inflammatory skin disorder that is characterized by scaly, erythematous, sharply demarcated plaques."( Iwatsuki, K; Katayama, N; Morizane, S; Motoki, T; Omori, M; Sugimoto, S, 2018)
"Psoriasis is a common inflammatory disease."( Hung, CF; Lee, GA; Li, HJ; Wu, NL, 2018)
"Psoriasis is a systemic inflammatory disease with a pathophysiology involving interleukin (IL)-17."( Berstein, G; Fitz, L; Fraser, S; Lee, J; Mebus, CA; Quazi, A; Soderstrom, C; Valdez, H; Wolk, R; Zhang, W, 2018)
"Psoriasis is a chronic skin condition whose pathogenesis is reported to be due to the activation of the interleukin-23/interleukin-17 (IL-23/IL-17) pathway."( Elizei, SS; Ghahary, A; Ghoreishi, M; Kilani, R; Mahmoudi, S; Pakyari, M, 2018)
"Psoriasis is a complex inflammatory and hyperproliferative skin disease."( Cabrini, DA; Dietrich, M; Fernandes, D; Horinouchi, CDS; Machado, W; Moreira, CG; Olchanheski, LR; Otuki, MF; Paludo, K; Pawloski, PL, 2018)
"Psoriasis is a chronic inflammatory disease associated with dyslipidemia, cardiovascular events, and mortality."( Ahlman, MA; Alavi, A; Armstrong, AW; Dey, AK; Duffin, KC; Fuxench, ZC; Gelfand, JM; Harrington, CL; Hubbard, RA; Joshi, AA; Kalb, RE; Mehta, NN; Menter, A; Playford, MP; Rader, DJ; Reilly, MP; Shin, DB; Simpson, EL; Takeshita, J; Torigian, DA; Troxel, AB; Tyring, SK; Van Voorhees, AS; Vanderbeek, SB; Werner, TJ, 2018)
"Psoriasis is a chronic, debilitating skin condition that affects approximately 125 million individuals worldwide."( Conic, R; Cooper, KD; McCormick, TS; Wang, Q; Ward, NL; Xu, R, 2017)
"Psoriasis is a chronic inflammatory skin disease dependent on the IL-23/IL-17 axis, a potent inflammatory pathway involved in pathogen clearance and autoimmunity."( Carey, CD; Diaz-Perez, JA; Falo, LD; Killeen, ME; Mathers, AR; Yang, Y, 2018)
"Psoriasis is a chronic, relapsing inflammatory skin disease."( Chen, C; Duan, Q; Liu, J; Liu, Z; Shao, Y; Wang, X; Wu, N; Yang, H; Yang, P; Zhang, M; Zheng, Y, 2018)
"Psoriasis is a complex chronic inflammatory skin disease characterized by epidermal thickening on the basis of increased keratinocyte proliferation and insufficient apoptosis."( Mizukami, Y; Morita, A; Natsumi, A; Paus, R; Sano, S; Sugawara, K; Tsuruta, D; Yasumizu, M, 2018)
"Psoriasis is a chronic inflammatory skin disease, primarily caused by overgrowth and abnormal differentiation of epidermal keratinocytes."( Cao, C; Pang, W; Qi, X; Zhang, S, 2018)
"Erythrodermic psoriasis is a rare but severe type of psoriasis that may be triggered by human immunodeficiency virus infection."( Fernández, J; Sánchez, M; Valenzuela, F; Zamudio, A, 2018)
"Psoriasis is a chronic skin disease caused by immune disorder."( Fukami, S; Kai, H; Morita, M; Moriuchi, M; Nakano, Y; Piruzyan, M; Shuto, T; Suico, MA; Takada, M; Tsurekawa, Y, 2018)
"Psoriasis is a chronic autoimmune disease mediated by dysregulated immune responses in dendritic cells (DC) and T cells."( Campbell, NK; Dunne, A; Fitzgerald, HK; Fletcher, JM; Hambly, R; Kirby, B; Malara, A; Sweeney, CM, 2018)
"Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression."( Green, LJ; Lin, T; Pariser, DM; Pillai, R; Stein Gold, L; Sugarman, JL, 2018)
"Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation of epidermal keratinocytes and infiltration of inflammatory cells."( Chen, C; Duan, Q; Jia, J; Jing, H; Li, C; Li, F; Liu, J; Shao, Y; Wang, N; Wang, Q; Wang, X; Xiao, L; Yang, P; Zheng, Y, 2019)
"Psoriasis is a chronic inflammatory disease, affecting more than millions of people in the world."( Gao, M; Si, X, 2018)
"Introduction Severe psoriasis is a chronic systemic immune‑mediated disease associated with increased cardiovascular (CV) risk and several comorbidities."( Bańska-Kisiel, K; Bergler-Czop, B; Biedroń, M; Brzezińska-Wcisło, L; Gąsior, Z; Haberka, M; Okopień, B, 2018)
"Psoriasis is a chronic and currently incurable inflammatory skin disease characterized by hyperproliferation, aberrant differentiation, and inflammation, leading to disrupted skin barrier function."( Adame, S; Adhami, VM; Babatunde, AS; Bharali, DJ; Chamcheu, JC; Esnault, S; Longley, BJ; Massey, RJ; Mousa, SA; Mukhtar, H; Siddiqui, IA; Wood, GS, 2018)
"Psoriasis is a chronic and benign proliferative skin disease."( Ho, CT; Li, S; Lin, CC; Wang, P; Yang, G; Yang, Y; Yuan, L; Zhao, H, 2018)
"Patients with psoriasis are at increased risk for cardiovascular comorbidities."( Huang, YC; Tsai, TY; Yen, H, 2019)
"Psoriasis is a multifaceted disease in terms of its pathophysiological mechanisms, inducing and aggravating factors, clinical types and clinical severity, associated comorbidities and therapeutic modalities."( Grozdev, I; Tsankov, N, 2018)
"Psoriasis is one of the most common chronic autoinflammatory skin disease, associated with hyperproliferation and abnormal differentiation of keratinocytes, inflammation, and angiogenesis."( Andreola, F; Calcaterra, A; Camponeschi, C; De Angelis, C; Giovannini, D; Nicotera, G; Pierimarchi, P; Serafino, A; Sferrazza, G; Zonfrillo, M, 2018)
"Psoriasis is an autoimmune skin disease characterized by hyperproliferation of keratinocytes due to interplay between keratinocytes and immune cells."( Abd El Hassib, DM; Doss, RW; El-Rifaie, AA; Kamal, MA; Sabry, D, 2018)
"Psoriasis is a chronic, systemic, inflammatory disease with manifestations resulting from a dysregulated immune response."( Augustin, M; French, LE; Krueger, JG; Pincelli, C; Schafer, PH, 2018)
"Psoriasis is a chronic condition often managed with topical therapy."( Kang, R; Kircik, LH; Lin, T; Pariser, D; Pillai, R; Stein Gold, L; Sugarman, JL, 2018)
"Psoriasis is a chronic, immune-mediated inflammatory disease characterized by localized scaling and plaques associated with itching and pain."( Cantrell, W; Gooding, K; Gorelick, J; Kucera, K; Veverka, KA, 2018)
"Psoriasis is a prevalent cutaneous condition with severe physical and psychological manifestations."( Curry, ZA; Feldman, SR; Heath, MS; Sahni, DR, 2018)
"Psoriasis is a distressing chronic skin disease."( Elgharib, I; Elsaid, HH; Khashaba, SA; Sharaf, MM, 2019)
"Psoriasis is characterized by keratinocyte hyperproliferation, erythema, as well as a form of pruritus, involving cutaneous discomfort."( Arkless, KL; Aubdool, AA; Brain, SD; Caton, P; Cleary, SJ; Evans, E; Kee, Z; Kodji, X; Pitchford, SC, 2019)
"Psoriasis is chronic inflammatory skin condition that imposes a significant physical and psychosocial burden on patients."( Armstrong, AW; Singh, S, 2018)
"Psoriasis is a chronic autoimmune disease with keratinocyte activation and lymphocyte infiltration in the skin."( Hsu, PY; Su, CC; Yang, HJ; Yang, TH, 2018)
"Psoriasis is a usual immune-mediated inflammatory skin disease with undefined pathogenesis."( Chen, HX; Dong, CZ; Du, ZY; Fang, YX; Li, PH; Li, YL; Liu, GR; Tang, YD; Yan, L; Zhang, K; Zhou, W, 2018)
"Psoriasis is an autoimmune and inflammatory skin disease affecting around 2-3% of the world's population."( Chen, Y; Dai, Z; Han, L; Liang, CL; Liu, H; Lu, C; Qiu, F; Zhang, Q, 2018)
"Psoriasis is a T-helper (Th)1/Th17-mediated chronic inflammatory disease."( Chandrashekar, L; Priyadarssini, M; Rajappa, M, 2019)
"Psoriasis is a common immune-mediated disease resulting from altered cross-talk between keratinocytes and immune cells."( Das Mahapatra, K; Meisgen, F; Pasquali, L; Pivarcsi, A; Sonkoly, E; Srivastava, A; Xia, P; Xu Landén, N, 2019)
"Psoriasis is a common skin disease pathogenically driven by TNF and IL-17A-induced epidermal hyperproliferation and inflammatory responses."( Auepemkiate, S; Chorachoo, J; Furnholm, T; Johnston, A; Lambert, S; Reingold, L; Roberts, L; Voravuthikunchai, SP, 2018)
"Psoriasis is a chronic inflammatory skin disorder that may be initiated or exacerbated by some drug intakes."( Badri, T; Charfi, O; El Aidli, S; Kastalli, S; Lakhoua, G; Zaïem, A, 2019)
"Psoriasis is a chronic inflammatory systemic disease characterized by a wide range of comorbidities."( Airoldi, A; Bragazzi, N; Colombo, D; Conic, R; Cristiano, A; Damiani, G; Goldust, M; Petrou, S; Pigatto, PDM; Radovanovic, D; Rizzi, M; Santus, P, 2018)
"Psoriasis is a common skin disorder characterized by hyperproliferation and aberrant differentiation of epidermal keratinocytes and inflammation."( Bao, W; Bollag, WB; Chen, X; Choudhary, V; Cohen, E; Hartney, B; Isales, CM; Patel, H; Patel, RR; Uaratanawong, R; Zhong, Q, 2019)
"Psoriasis is a common chronic disease with accelerated epidermal cell growth."( Chen, J; Chen, M; Chen, X; Huang, X; Wu, X; Zeng, W, 2019)
"Psoriasis is a chronic immune-medicated inflammatory condition that affects 2-3% of the population, which can lead to psoriatic arthritis."( Chen, C; Gettas, T; Messiah, R; Metyas, S; Quismorio, A; Tomassian, C, 2019)
"Psoriasis is a chronic inflammatory skin disease in which inflammatory cytokines play a major role in its pathogenesis."( Hara, Y; Kawada, A; Kitahata, K; Matsuo, K; Naganuma, T; Nakayama, T; Oiso, N, 2018)
"Psoriasis is a prevalent, chronic inflammatory skin disease that arises from rapid and excessive growth of keratinocytes induced by abnormal inflammatory responses."( Ba, W; Chi, S; Li, C; Wang, R; Wang, Y; Xu, Y; Yang, J; Yin, G, 2019)
"Psoriasis is a chronic, immune-mediated inflammatory skin disease."( Chen, M; Li, Y; Tang, F; Tong, M; Wen, H; Xiao, R; Zhang, G; Zhao, M, 2019)
"Psoriasis is a common autoimmune disease (AID) and HSCT is a potential treatment for severe AIDs."( Chen, W; Huang, X; Ren, G; Zuo, K, 2018)
"Background: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression."( Lebwohl, M; Stein Gold, L; Tanghetti, E, 2018)
"Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated by the interplay of T cells and polymorphonuclear granulocytes."( Becher, B; Cheng, P; Conrad, C; Dummer, R; Flatz, L; Hartwig, T; Navarini, A; Schlapbach, C; Schreiner, B; Yawalkar, N; Zwicky, P, 2018)
"Psoriasis is a common chronic inflammatory skin disease which lacks effective strategies for the treatment."( Bai, J; Cai, W; Chen, L; Gao, Y; Li, Q; Lou, F; Lu, S; Niu, L; Sun, Y; Wang, H; Wang, Z; Wei, Z; Xu, Z; Yin, Q; Zhang, J; Zhou, A; Zhou, H, 2019)
"Psoriasis is a chronic inflammatory disorder that imposes a substantial economic burden."( Duvetorp, A; Engerstedt Mattsson, E; Levin, LÅ; Ryttig, L, 2019)
"Psoriasis is a chronic inflammatory autoimmune skin disease that often occurs in rubbed areas undergoing a strong mechanical stretch, such as the elbows and knees."( Dang, E; Fang, H; Guo, W; Jiang, M; Ke, Y; Qiao, H; Qiao, P; Shen, S; Wang, G; Zhang, J; Zhuang, Y, 2019)
"Psoriasis is a chronic inflammatory skin disorder that affects ~2%-3% of the worldwide population."( Catherine Jin, SL; Chang, CH; Chuang, TH; Hsu, LC; Lai, CY; Liu, YL; Lu, CH; Su, YW; Yeh, DW, 2018)
"Scalp psoriasis is a major therapeutic challenge due to the hindrance caused by hair."( Pakornphadungsit, K; Phusuphitchayanan, P; Rattanakaemakorn, P; Suchonwanit, P; Thadanipon, K, 2019)
"Psoriasis is a chronic hyperproliferative skin disease characterised by excessive growth of keratinocytes."( Chen, H; Duan, J; Duan, X; Gan, L; Liu, D; Liu, X; Lu, X; Poorun, D; Zhang, S, 2019)
"Psoriasis is a chronic inflammatory skin disease with unknown aetiology."( Aadil, W; Akhtar, T; Chopra, D; Kaur, R; Kumar, S; Narang, T; Rawat, AK, 2018)
"Psoriasis is an inflammatory skin disorder characterized by the hyperproliferation of basal epidermal cells."( Bivik Eding, C; Ekman, AK; Enerbäck, C; Rundquist, I, 2019)
"Nail involvement in psoriasis is common, and the severity of it does not always parallel the intensity of cutaneous disease."( Baran, R; Chiheb, S; Daniel, CR; Di Chiacchio, N; Gregoriou, S; Grover, C; Haneke, E; Iorizzo, M; Pasch, M; Piraccini, BM; Rich, P; Richert, B; Rigopoulos, D; Rompoti, N; Rubin, AI; Singal, A; Starace, M; Tosti, A; Triantafyllopoulou, I; Zaiac, M, 2019)
"Psoriasis is a chronic recurrent skin inflammatory disease, and inhibition of inflammation may be an effective means of treating psoriasis."( Chen, H; Dai, Z; Han, L; Huang, H; Li, L; Lu, C; Lu, Y; Wang, A; Wei, J; Zhong, X, 2019)
"Psoriasis is a chronic, inflammatory multisystem disease that affects up to 3."( Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Prater, EF; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Wong, EB; Wu, JJ, 2019)
"Psoriasis is a chronic inflammatory skin disease that is increasingly being recognized as a complex disorder affecting multiple systems."( Chiricozzi, A; Girolomoni, G; Gisondi, P, 2019)
"Psoriasis is a chronic skin disorder that manifests as epidermal keratinocyte hyperplasia."( Bo, KP; Gao, Q; Ma, AL; Ma, W; Shi, HJ; Song, HB; Wang, L; Zhang, N; Zhou, H, 2019)
"Psoriasis is now recognized as an immune-mediated inflammatory dermatosis with increased risk for metabolic syndrome, its individual components, and cardiovascular disease."( Bhushan, S; Chauhan, PS; Chauhan, S; Mahajan, VK; Mehta, KS; Sharma, A; Sharma, V; Wadhwa, D; Yadav, RS, 2019)
"Psoriasis is a chronic skin disease that affects approximately two per cent of the general population."( Droitcourt, C; Dupire, G; Hughes, C; Le Cleach, L, 2019)
"Psoriasis is a chronic inflammatory skin disease with unresolved pathogenesis."( Feng, L; Guo, M; Huang, W; Kong, L; Shao, F; Song, P; Wu, X; Xu, F; Xu, L; Xu, Q, 2019)
"Psoriasis is a chronic skin disease characterized by hyperproliferation and impaired differentiation of epidermal keratinocytes accompanied by increased inflammation, suggesting that molecules with antiproliferation and anti-inflammatory abilities may be effective for its treatment."( Cui, J; Gong, Y; Liang, C; Liu, X; Shao, C; Sun, S; Tian, F; Wang, Q; Wei, H; Wu, G; Xia, Y; Xu, B; Xu, M; Yang, G; Zhang, F; Zhang, L; Zhang, X; Zhao, H; Zhou, S; Zou, Y, 2019)
"Psoriasis is a chronic inflammatory skin disease arising from a complex interaction between genetics, epigenetics, the host's immune system and the environment."( Hirankarn, N; Meephansan, J; Reantragoon, R; Ruchusatsawat, K; Soonthornchai, W; Tangtanatakul, P; Wongpiyabovorn, J, 2021)
"Psoriasis is a multisystem disease affecting about 2% of the population, while keratin16 (KRT16) has been reported to participate in psoriasis."( Cai, TG; Chen, JG; Fan, HY; Lin, LY; Wang, T, 2019)
"Psoriasis is a chronic immune mediated disorder of the skin."( Arumugam, M; Jeyaraman, J; Nandakumar, MP; Prabhu, D; Sundarrajan, S, 2020)
"Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of the epidermal cells and is clinically presented as thick, bright red to pink plaques with a silvery scale."( Gomez, C; Muangnoi, C; Rojsitthisak, P; Sorasitthiyanukarn, FN; Wongpiyabovorn, J, 2019)
"Psoriasis is an autoimmune chronic dermatosis that is T cell-mediated, characterized by epidermal thickening, aberrant epidermal differentiation and inflammatory infiltrates, with a dominant Th1 and Th17 profile."( Lorthois, I; Morin, S; Pouliot, R; Simard, M, 2019)
"Psoriasis is a T helper type 17-mediated immune disease."( Eyerich, K; Garzorz-Stark, N, 2019)
"The prevalence of psoriasis is increasing, and poses a serious risk to human health and quality of life."( Deng, H; Fan, X; Li, F; Meng, Q; Sun, R; Yan, K; Yang, X; Yuan, D, 2019)
"Psoriasis is a chronic inflammatory and immune-mediated skin disease."( Chen, HX; Dong, CZ; Du, ZY; Gu, YH; Li, PH; Zhang, WJ; Zhao, MC, 2019)
"Psoriasis is a common, chronic inflammatory disease characterized by abnormal skin plaques, and the effectiveness of phosphodiesterase 4 (PDE4) inhibitor to lessen the symptoms of psoriasis has been proved."( Chen, W; Dong, G; Feng, C; Gu, Z; Li, H; Li, J; Li, M; Liu, H; Tang, W; Xu, Y; Zhang, R; Zhang, X; Zhu, F, 2019)
"Treatment of psoriasis is always difficult, which requires intensive scientific research."( Duan, Y; Guo, D; Guo, W; Jin, W; Mao, J; Wu, M; Xu, N; Zhang, Y; Zhou, J; Zou, J, 2019)
"Psoriasis is a common chronic relapsing immune-mediated inflammatory disease, the prevalence of which has increased in recent years."( Jiang, W; Li, B; Li, H; Li, X; Ma, T; Shen, F; Sun, X; Xie, S; Xu, W; Zheng, Q, 2019)
"Psoriasis is a chronic, recurrent, immune-mediated, hyperproliferative inflammatory skin disease."( Ataide, M; Catarino, JS; Estevam, RB; Furiati, SC; Pereira, SL; Rodrigues, DBR; Rodrigues, V; Silva, MV; Silva, RF; Teodoro, RB, 2019)
"Psoriasis is an immune‑mediated cutaneous disorder with a high incidence and prevalence."( Gao, XH; Qi, RQ; Sun, YZ; Zhang, YJ, 2019)
"Psoriasis is a common inflammatory skin disease."( Chen, H; Chen, Y; Dai, Z; Deng, J; Han, L; Huang, H; Liu, C; Liu, H; Lu, C; Wei, J; Xu, YY; Yan, Y, 2019)
"Psoriasis is a chronic inflammatory disease associated with multiple comorbidities, particularly in patients with arthritis or more severe forms of the disease."( Aguado, P; Carrascosa, JM; Daudén, E; Muñoz-Torres, M; Rivera, R, 2019)
"Psoriasis is an autoimmune disorder disease with pink-colored plaques and excessive proliferation which is hard to be cured completely."( Cao, X; Cheng, G; Cheng, X; Li, J; Piao, H; Yin, X; Zou, M, 2019)
"Psoriasis is a chronic inflammatory disease that affects 1."( Arnone, M; Azulay-Abulafia, L; Bernardo, WM; Bortoletto, MCC; Bressan, AL; Carvalho, AVE; Felix, PAO; Fieri, LC; Jaime, TJ; Magalhaes, RF; Neffá, JM; Nunes, DH; Oliveira, MFSP; Ramos, AMC; Romiti, R; Souza, CDS; Takahashi, MDF; Terena, AC, 2019)
"Psoriasis is a chronic, immune-mediated inflammatory skin disease, and the inflammatory response plays an important role in its development and progression."( Cheng, YG; Guan, W; Guo, S; Kuang, HX; Liu, Y; Tan, JY; Yang, BY, 2019)
"Psoriasis is a chronic inflammatory skin disease characterized by keratinocyte hyperproliferation."( Chen, J; Chen, Y; Chen, Z; Fan, H; Gu, J; Shi, Y; Wang, Y; Yu, Z; Zhang, X; Zhou, Q, 2019)
"Psoriasis is a common chronic inflammatory skin disease, and the infiltrated macrophages in psoriatic skin lesions play a key role in the progression of this uncontrolled cutaneous inflammation."( Chen, W; Deng, G; Gu, Z; Ji, X; Sun, Y; Wang, P; Wang, X; Zhan, T; Zheng, W, 2019)
"Psoriasis is a chronic inflammatory skin disease characterized by excessive growth of keratinocytes and hyperkeratosis in the epidermis."( Chen, SL; Ho, TC; Tsao, YP; Yeh, SI, 2019)
"Psoriasis is an immune-mediated chronic inflammatory skin disease that is seen in 1%–3% of the population."( Akdeniz, N; Elmas, ÖF; Kızılyel, O; Metin, MS, 2019)
"Psoriasis is a common chronic inflammatory multisystemic disease with a complex pathogenesis consisting of genetic, immunological, and environmental components."( Arenas-Guzmán, R; Carnero-Gregorio, M; Cordeiro-Rodríguez, M; Fabbrocini, G; González-Cespón, JL; López-Barcenas, A; Martínez-Herrera, E; Rodríguez-Cerdeira, C; Sinani, A, 2019)
"Psoriasis is a systemic disease associated with metabolic syndrome and cardiometabolic diseases."( Baran, A; Flisiak, I; Kiluk, P; Maciaszek, M; Myśliwiec, H; Świderska, M, 2019)
"Psoriasis is a severe disfiguring skin disease affecting approximately 3% of people worldwide and negatively affecting their daily lives."( Lin, Z; Liu, Z; Meng, S; Sun, L; Wang, L; Wang, Z; Xi, L; Zheng, Y, 2019)
"Psoriasis is a multifactorial systemic disease with predominantly cutaneous manifestations."( Giácaman-von der Weth, M; Hernández-Bel, P; Partarrieu-Mejías, F; Pérez-Ferriols, A, 2019)
"Psoriasis is an immune system meditated disease, especially T cells."( Chen, Y; Fang, W; He, S; Huang, L; Leng, Y; Li, B; Li, Y; Liu, D; Liu, G; Liu, R; Liu, X; Wang, R; Yang, Z; Ye, C; Yin, H, 2019)
"Psoriasis is a chronic inflammatory skin disease."( Fukaya, S; Fukuyasu, A; Hayashi, K; Ishikawa, T; Kamata, M; Ohnishi, T; Shimizu, T; Tada, Y; Tanaka, T, 2019)
"Psoriasis is a chronic inflammatory systemic disease caused by deregulation of the interleukin-23/-17 axis that allows the activation of Th17 lymphocytes and the reprogramming of keratinocytes proliferative response, thereby inducing the secretion of cyto-/chemokines and antimicrobial peptides."( Bernardini, N; Calogero, A; Carlomagno, S; Chiantore, MV; Iuliano, M; Mangino, G; Potenza, C; Romeo, G; Rosa, P; Skroza, N, 2019)
"Psoriasis is a chronic inflammatory skin disease characterized by IL-17-mediated immune responses."( Dainichi, T; Egawa, G; Garcet, S; Ghosh, S; Grinberg-Bleyer, Y; Guttman-Yassky, E; Honda, T; Iwakura, Y; Kabashima, K; Kitoh, A; Krueger, JG; Matsumoto, R; Nakajima, S; Nakano, Y; Nomura, T; Otsuka, A; Otsuka, M; Sakurai, K; Sugimoto, Y; Tsuchiya, S; Yamamoto, Y, 2019)
"Psoriasis is a common inflammatory skin disorder with complex pathomechanisms."( Abdelshafey, AS; Attwa, EM; Elkot, RA; Hafez, AR, 2019)
"Psoriasis is a skin chronic inflammatory disease with a complex aetiology."( Cannavò, SP; Casciaro, M; Di Salvo, E; Gangemi, S; Riso, G, 2019)
"Psoriasis is an immune-mediated inflammatory skin disease that mainly affects the skin barrier."( Chen, H; Dai, Z; Deng, J; Han, L; Liang, CL; Liu, C; Liu, H; Lu, C; Wang, Y; Wei, J; Yan, Y, 2019)
"Psoriasis is commonly treated with topical corticosteroids, oral cytotoxic drugs and biologic agents, which can be associated with significant adverse effects (AEs), high cost and response attenuation."( Alex, P; Centola, M; Sutton, C; Sutton, L; Thomas, S; Williams, S; Yesudas, T, 2020)
"BACKGROUND: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression."( , 2019)
"Psoriasis is a chronic inflammatory skin disease associated with quality of life (QoL) impairment."( Falques, M; Loewe, R; Mrowietz, U; Pau-Charles, I; Szepietowski, JC; van de Kerkhof, PCM, 2020)
"Psoriasis is a frequent systemic inflammatory autoimmune disease characterized primarily by skin lesions with massive infiltration of leukocytes, but frequently also presents with cardiovascular comorbidities."( Archer, NK; Bittner, Z; Businger, R; Codrea, MC; Ghoreschi, K; Grabbe, S; Heister, M; Herster, F; Heumos, S; Löffler, MW; Miller, LS; Schäkel, K; Schindler, M; Stegner, D; Weber, ANR; Wegner, J, 2019)
"Psoriasis is hallmarked by vascular dysfunction, arterial hypertension, and an increased risk for cardiovascular diseases."( Daiber, A; Karbach, SH; Knopp, T; Kossmann, S; Molitor, M; Münzel, T; Schüler, R; Waisman, A; Wenzel, P; Wild, J, 2019)
"Psoriasis is a common and intractable skin disease affecting the physical and mental health of patients."( Wang, H; Wang, W, 2019)
"Psoriasis is a chronic, systemic, hyper-proliferative immune-mediated inflammatory skin disease."( Kong, Y; Peng, D; Su, X; Su, Y; Wu, R; Zhang, S; Zhao, M, 2019)
"Psoriasis is a chronic dermatologic disease affecting 2% of the general population."( Bulut, H; Engin, B; Gökalp, E; Kutlubay, Z; Özkoca, D; Serdaroğlu, S; Songür, A; Tanakol, A; Tüzün, Y; Vehid, HE, 2020)
"Psoriasis is a common dermatosis causing considerable inconvenience to 4% of the general population."( Bao, YL; Jiang, BW; Jing, QQ; Li, WJ; Li, YX; Liu, L; Liu, YC; Song, ZB; Tan, LP; Yang, XG; Yu, CL, 2019)
"Background: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression."( Bhatia, ND; Green, LG; Lin, T; Martin, G; Vlahovic, TC, 2019)
"Psoriasis is a chronic inflammatory skin disease with a genetic and autoimmune background."( Allam, JP; Brendes, K; Bunzek, C; Haidl, G; Heltzel, M; Novak, N; Schnell, L; Weckbecker, L; Wilsmann-Theis, D, 2019)
"Psoriasis is a chronic inflammatory skin disease with numerous involved factors."( Abram, K; Kaldvee, B; Kingo, K; Kivihall, A; Maslovskaja, J; Mrowietz, U; Prans, E; Raam, L; Rebane, A; Runnel, T; Vaher, H; Weidinger, S, 2020)
"Psoriasis is an inflammatory skin disease that affects 1%-3% of Caucasian populations and may be persistent, disfiguring and stigmatising."( Bafutto, M; Oliveira, EC; Zaterka, S, 2019)
"Psoriasis is a chronic, multifactorial, inflammatory disorder, with an estimated prevalence of 0."( AlMutairi, N; Nour, T, 2020)
"Psoriasis is a multifactorial skin disease involving abnormal cell proliferation and inflammation; an efficacious topical treatment is yet to be identified."( Banov, D; Bassani, AS; Ip, K; Song, G; Valdez, BC, 2020)
"Psoriasis is caused by a complex interplay among the immune system, genetic background, autoantigens, and environmental factors."( Lin, X; Meng, X; Song, Z, 2019)
"Psoriasis is an autoregulated immune and inflammation-based skin disease affecting approximately 3-4% of the worldwide population."( Ai, D; Feng, S; Liu, Y; Ma, J; Yang, X, 2019)
"Psoriasis is a chronic, multisystem, inflammatory disease that affects approximately 1% of children, with onset most common during adolescence."( Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Farley Prater, EA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Wong, EB; Wu, JJ, 2020)
"Although psoriasis is a proven testing ground for treatment-response prediction using transcriptomic data from clinically accessible skin biopsies, these biopsies are expensive, invasive, and challenging to obtain from certain body areas."( Berstein, G; Correa da Rosa, J; Fitz, LJ; Kim, J; Krueger, JG; Lee, J; Suárez-Fariñas, M; Tomalin, LE; Valdez, H; Wolk, R, 2020)
"Psoriasis is considered an immune-mediated inflammatory skin disorder that affects the quality of life of nearly four percent of the world population."( Bao, YL; Jiang, BW; Li, YX; Liu, L; Song, ZB; Tan, LP; Wang, SY; Wang, Y; Yu, CL; Zhang, WJ, 2020)
"Psoriasis is a disease that commonly manifests in adolescence."( Eichenfield, LF; Kurvits, M; Liljedahl, M; Marcoux, D, 2020)
"Psoriasis is a chronic, recurrent inflammatory autoimmune skin disease."( Feng, H; Kong, Y; Liu, Z; Lu, Q; Su, Y; Wang, H; Wu, H; Wu, R; Zhang, S; Zhao, M, 2020)
"Psoriasis is a cutaneous disease mainly characterized by keratinocyte hyperproliferation, abnormal epidermal differentiation, inflammation and angiogenesis."( Huang, C; Le, K; Sun, Y; Wu, S; Xie, M; Xu, M; Zhao, M, 2020)
"Psoriasis is a chronic, immune-mediated disorder with chronic plaque psoriasis being the primary manifestation during the remission stage."( Chen, Z; Di, T; Duan, X; Feng, S; Guo, X; Lan, H; Li, B; Li, P; Li, W; Liu, Z; Wang, Y; Zhang, J; Zhao, J; Zhou, D, 2019)
"Psoriasis is a widespread chronic disease affecting 1-3 % of total population."( Gupta, AR; Joshi, SV; Maulvi, FA; Pandey, SS; Patel, PS; Shah, DO; Shah, KM; Shukla, MR, 2020)
"Psoriasis is an autoimmune skin disease caused by interactions between keratinocytes and immune cells, such as macrophages."( Hu, J; Jin, X; Li, D; Tang, L; Wang, Y; Xia, C; Xu, H, 2020)
"Psoriasis is an autoimmune skin disease, where hyperproliferation of keratinocytes and exaggerated immune responses are the important hallmarks of the disease."( Godugu, C; Pooladanda, V; Thatikonda, S, 2020)
"Psoriasis is a chronic, inflammatory skin disease with high incidence and high rates of relapse, for which no satisfactory treatments are currently available."( Chen, D; Jia, J; Li, H; Lin, Y; Liu, J; Mo, X; Wang, N; Yan, F; Zheng, Y, 2020)
"Psoriasis is a common inflammatory skin disorder that is characterized by keratinocyte hyperproliferation and abnormal differentiation, resulting in the thickening of the epidermis and stratum corneum."( Hiebert, P; Kim, TG; Kim, YS; Lee, J; Song, K; Werner, S, 2020)
"Psoriasis is a T cells mediated chronic skin inflammation in which helper T (Th) cells play in critical roles in its pathogenesis."( Du, Z; Li, N; Lu, C; Wu, D; Yuan, X; Zhang, M; Zhu, W, 2020)
"Psoriasis is a refractory skin disease characterized by macrophage cell infiltrated in the dermal layer."( Chen, H; Han, L; Li, L; Lu, C; Lu, Y; Wei, J; Zhang, HY; Zhong, XQ, 2020)
"Psoriasis is a skin disorder characterized by epidermal hyperplasia, hyperkeratosis, and inflammation."( Bélanger, A; Gendreau, I; Grenier, A; Legault, J; Pichette, A; Pouliot, R; Simard, F, 2019)
"Psoriasis is an autoimmune skin disease, where chronic immune responses due to exaggerated cytokine signaling, abnormal differentiation, and evasion of keratinocytes apoptosis plays a crucial role in mediating abnormal keratinocytes hyperproliferation."( Godugu, C; Pooladanda, V; Sigalapalli, DK; Thatikonda, S, 2020)
"Palmoplantar psoriasis is a localised variant of psoriasis."( Andanooru Chandrappa, NK; Channakeshavaiah Ravikumar, B; Rangegowda, SM, 2020)
"Psoriasis is an autoinflammatory/autoimmune skin disease and the epitome of an exaggerated primary inflammatory response in the surface barrier tissue."( Fujimoto, M; Fujisawa, Y; Furuta, J; Inoue, S; Ishitsuka, Y; Nakamura, Y; Ogawa, T; Okiyama, N; Saito, A; Watanabe, R, 2020)
"Psoriasis is an unchecked chronic inflammation characterized by thick, erythematous, and scaly plaques on the skin."( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alanazi, WA; Alasmari, AF; Alasmari, F; Attia, SM; Bakheet, SA; El-Sherbeeny, AM; Ibrahim, KE; Nadeem, A, 2020)
"Many patients with psoriasis are bothered by symptoms in highly visible, pruritic areas, such as the scalp."( Cauthen, A; Lebwohl, M; Lynde, C; Paris, M; Sofen, H; Stein Gold, L; Strober, B; Tyring, S; Van Voorhees, AS; Wang, Y; Zhang, Z, 2020)
"Since psoriasis is an immuno-mediated skin disease, long-term therapies are necessary for its treatment."( Bentley, MVLB; Caron, AL; Del Ciampo, JO; Kravicz, M; Medina, WSG; Praça, FG; Silvestrini, AVP; Suzuki, I; Viegas, JSR, 2020)
"Psoriasis is a chronic immune-mediated skin disease, with a pathogenesis resulting from a combination of genetic and environmental factors."( Ascenso, A; Martins, AM; Marto, J; Ribeiro, HM, 2020)
"Psoriasis is a common autoimmune and chronic inflammatory skin disorder globally affecting 0."( Chen, H; Duan, X; Huang, Y; Jin, Z; Liu, N; Liu, X; Ming, Z; Zhang, S, 2020)
"Psoriasis is a common non-contagious chronic inflammatory skin lesion, with frequent recurrence."( Chang, DC; Hsiao, CY; Hung, CF; Li, HJ; Pu, CM; Wu, NL, 2020)
"Psoriasis is a chronic inflammatory disease involving multiple organ systems and affecting approximately 2% of the world's population."( Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Prater, EF; Rahimi, RS; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Tapper, EB; Wong, EB; Wu, JJ, 2020)
"Psoriasis is a chronic inflammatory skin disease characterized by dysregulated keratinocyte differentiation, but oxidative stress also plays an important role in the pathogenesis of this disease."( Biernacki, M; Gęgotek, A; Jarocka-Karpowicz, I; Skrzydlewska, E; Wroński, A, 2020)
"Psoriasis is a skin inflammatory disorder that affects 3% of the human population."( Cayuela, ML; Corbalán-Vélez, R; García-Moreno, D; López-Muñoz, A; Martínez-Menchón, T; Martínez-Morcillo, FJ; Martínez-Navarro, FJ; Mulero, V; Pardo-Sánchez, I; Pérez-Oliva, AB, 2020)
"Psoriasis is a chronic immune-mediated inflammatory dermatosis."( Cheng, H; Cheng, Q; Ding, S; Dou, J; Gao, L; Guo, A; Lei, L; Lu, J; Luo, Z; Tan, L; Yang, C; Zeng, J; Zeng, Q; Zhang, B, 2020)
"Psoriasis is a common non-communicable chronic immune-mediated skin disease, affecting approximately 125 million people in the world."( Ascenso, A; Martins, AM; Marto, J; Ribeiro, HM, 2020)
"Psoriasis is clinically characterized by well-demarcated silvery plaques which may appear on the extremities, scalp, and sacral area."( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alotaibi, MR; Alqahtani, F; Alzahrani, KS; Attia, SM; Bakheet, SA; El-Sherbeeny, AM; Ibrahim, KE; Mahmood, HM; Nadeem, A, 2020)
"Psoriasis is a common inflammatory skin condition, affecting 2-4% of the worldwide population."( Bianchi, L; Campione, E; Cesaroni, GM; Chiaramonte, C; Chimenti, MS; Cosio, T; Dattola, A; Galluzzo, M; Gaziano, R; Gisondi, P; Lanna, C; Mazzilli, S; Palumbo, V; Zangrilli, A, 2020)
"Psoriasis is a skin disease characterized by abnormal keratinocyte proliferation and inflammation."( Civelli, M; Facchinetti, F; Pambianchi, E; Sticozzi, C; Valacchi, G; Villetti, G; Woodby, B, 2020)
"Psoriasis is an inflammatory skin disease associated with itch, which is a troublesome symptom with a few therapeutic options."( Berta, T; Choi, Y; Jung, SJ; Lee, SH; Tonello, R, 2020)
"Psoriasis is a chronic, immune-mediated inflammatory skin disease and highly depends on inflammation and angiogenesis as well as other pathways."( Cheng, Y; Guan, W; Jiang, P; Kuang, H; Liu, Y; Sun, Y; Tan, J; Yang, B, 2020)
"Psoriasis is a chronic recurrent inflammatory disease."( Chang, W; Hou, R; Jiao, J; Li, J; Li, X; Liang, N; Liang, Y; Wang, Y; Xing, J; Zhang, K, 2020)
"Psoriasis is a chronic inflammatory skin disease with unclear pathogenesis."( Chen, J; Chen, R; Chen, Y; Chen, Z; Cui, L; Diao, H; Gong, Y; Hu, Y; Shi, Y; Wang, Y; Yu, Q; Yu, Y; Zhang, X, 2020)
"Psoriasis is a persistent and recurrent chronic inflammatory skin disease that is characterized by inflammation and increased proliferation of keratinocytes."( Deng, X; Li, Q; Wang, J; Wu, X, 2020)
"Psoriasis is a chronic autoinflammatory disorder characterized by patches of abnormal skin."( Aydın, A; Erol, İ; Orak, D; Özer, Ö; Sipahi, H; Üstündağ Okur, N, 2020)
"Chronic plaque psoriasis is an immune-mediated, chronic, inflammatory skin disease, which can impair quality of life and social interaction."( Chan, D; Chan, T; Gambichler, T; Harari, M; Labeit, AM; Peinemann, F; Peternel, S, 2020)
"Psoriasis is a systemic immune-mediated disease for which MSCs could have therapeutic potential."( Benassi, L; Kaleci, S; Magnoni, C; Paganelli, A; Tarentini, E, 2020)
"Psoriasis is a chronic inflammatory autoimmune skin condition that affects millions of people worldwide."( Angelatos, AS; King, NJC; Macia, L; Mazur, E; Niewold, P; Pinget, GV; Tan, J, 2020)
"Psoriasis is one of the common chronic inflammatory skin diseases in which inflammatory cytokines such as IL-17 and TNF-α play critical roles."( Matsushima, Y; Mizutani, K; Okada, K; Yamanaka, K, 2020)
"Scalp psoriasis is common in psoriasis patients, difficult to treat and manifests a significant burden on quality of life."( Alsenaid, A; Ezmerli, M; Heppt, M; Illigens, BM; Prinz, JC; Srour, J, 2022)
"Psoriasis is a chronic disease and often requires long-term treatment, especially in patients with moderate-to-severe psoriasis."( Chen, M; Lian, N; Liu, L; Shi, L, 2020)
"Psoriasis is characterized by excessive growth and aberrant differentiation of epidermal keratinocytes due to persistent inflammation."( Hara, T; Ishido, Y; Ishii, N; Kambara, T; Kawashima, A; Luo, Y; Suzuki, K; Suzuki, S, 2020)
"Psoriasis is a common chronic inflammatory skin disorder that is associated with excess cardiovascular risk."( Blankstein, R; Brown, JM; Di Carli, M; Divakaran, S; Dorbala, S; Liao, K; Merola, JF; Perez-Chada, LM; Taqueti, V; Weber, B, 2022)
"Psoriasis is a common, chronic multifactorial inflammatory skin disease with both genetic and environmental components."( Di, T; Fu, J; Guo, J; Li, N; Li, P; Meng, Y; Wang, Y; Zhang, L; Zhao, J, 2020)
"Psoriasis is a common chronic skin disease characterized by epidermal proliferation and inflammation."( Ding, Y; Li, Y; Lu, J; Shi, Y; Xu, X; Yu, N, 2020)
"Psoriasis is a chronic relapsing inflammatory and hyperproliferative skin disease affecting quality of life."( Awasthi, R; Jindal, S; Kulkarni, GT; Singhare, D, 2020)
"Psoriasis is a chronic immune-mediated inflammatory skin disease without effective treatment."( Du, YZ; Huang, QL; Lu, KJ; Qi, J; Shu, GF; Sun, MC; Tan, WQ; Wang, W; Xu, XL, 2020)
"Psoriasis is a chronic inflammatory skin condition known to affect about 1%-3% of the global population."( D, S; Dogra, S; Rajagopalan, M, 2020)
"Psoriasis is a common chronic inflammatory skin disease."( Cao, M; Chen, CY; Li, B; Li, H; Li, X; Ma, T; Peng, S; Sun, X; Zhou, Y; Zhu, B, 2020)
"Psoriasis is a recrudescent chronic immune-mediated inflammatory dermatosis; the production and release of proinflammatory cytokines/chemokines such as TNF-α has been regarded as critical issues during psoriasis pathogenesis."( Huang, P; Luomei, J; Peng, Y; Wang, H; Zhang, Y; Zhou, R, 2020)
"Psoriasis is a very common chronic inflammatory skin disease affecting up to 3% of the general population with 75% of the psoriasis subjects being affected by a mild form of disease."( Camela, E; Cinelli, E; Fabbrocini, G; Megna, M, 2020)
"Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the population worldwide."( Fang, H; Gao, J; Guo, J; Mi, J; Mo, W; Nong, Y; Qi, Q; Yang, M, 2020)
"Psoriasis is a chronic immune-mediated inflammatory cutaneous disorder with Th17 cells and Th17-related cytokines playing an important role in its development."( Lane, JA; Lei, K; Li, Y; Lin, L; Sun, L; Wang, D; Zeng, J; Zhang, L; Zuo, D, 2020)
"Psoriasis is a chronic, systemic disease with features suggestive of autoimmune dysregulation."( Abramovits, W; Schlessinger, J, 2020)
"Psoriasis is a chronic inflammatory disease whose etiology is multifactorial."( Bai, J; Cai, X; Chen, X; Deng, S; Ginhoux, F; Gu, J; Li, Q; Liu, Z; Lou, F; Niu, L; Shi, YL; Sun, L; Sun, Y; Tao, W; Wang, H; Wang, Z; Wu, Z; Xu, Z; Yin, Q; Zhou, H, 2020)
"Psoriasis is a chronic relapsing inflammatory skin disease, affecting up to 3% of the global population."( Gao, WW; Li, GQ; Liang, SJ; Sun, DD; Wang, T; Wu, S; Xu, F; Xu, GL; Yang, Y; Zheng, QY; Zhong, Y, 2020)
"Psoriasis is a common inflammatory skin disease characterized by hyperproliferation of epidermal keratinocytes, however, there is still no curative therapy for psoriasis."( Bai, X; Dang, E; Luo, Y; Wang, G; Yang, L; Yu, C; Zhi, D, 2020)
"Psoriasis is an autoimmune disease of the skin with lapsing episodes of hyperkeratosis, irritation, and inflammation."( Dadwal, A; Mishra, N; Narang, RK, 2021)
"Psoriasis is a chronic inflammatory skin disease that is thought to affect ∼2% of the global population."( Brain, SD; Caton, PW; Evans, EA; Frame, J; Hannen, RF; Kodji, X; Philpott, MP; Rizvi, A; Sayers, SR; Shaikh, M; Xia, Y, 2020)
"Psoriasis is a chronic inflammatory disease that can be effectively treated using topical cyclosporine."( Chen, H; Li, F; Li, Q; Qi, X; Wang, T; Wei, F, 2020)
"Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation and abnormal differentiation of epidermal keratinocytes accompanied by increased infiltration of immune cells."( Choi, YA; Jang, YH; Kang, J; Kim, N; Kim, SH; Kwon, TK; Lee, B; Lee, S, 2020)
"Psoriasis is a prevalent chronic inflammatory skin disease characterized by thickening of the epidermis accompanied by lesional erythema, scaling, and induration as a result of abnormal proliferation of keratinocytes."( Jon, S; Jung, W; Keum, H; Kim, D; Kim, J; Kim, TW; Kim, Y; Seo, C; Son, Y; Whang, CH, 2020)
"Psoriasis is a common immune-mediated, chronic inflammatory genetic-related disease that affects patients' quality of life."( Chen, C; Chen, X; Kuang, Y; Lei, L; Li, J; Liu, P; Peng, C; Tan, L; Zhu, W, 2020)
"Psoriasis is an inflamed skin disorder associated with the activation of phosphorylation signals in keratinocytes, which leads to proliferation."( Anbardar, MH; Chavoshy, F; Tamaddon, AM; Zadeh, BSM, 2020)
"Psoriasis is a chronic inflammatory skin disease characterized by well‑defined scaly papules and plaques."( Gao, XH; Geng, L; Guo, H; Lan, XO; Qi, RQ; Wang, HX; Xu, YY; Yang, Y; Yu, YJ, 2020)
"Nail psoriasis is also considered a risk factor for the development of psoriatic arthritis (PsA)."( Azad, J; Takwale, A; Thomas, L, 2021)
"Psoriasis is a pathological condition characterized by immune system dysfunction and inflammation."( Andrys, C; Beranek, M; Borska, L; Borsky, P; Fiala, Z; Hamakova, K; Holmannova, D; Krejsek, J; Malkova, A; Palicka, V; Rehacek, V; Svadlakova, T, 2020)
"Psoriasis is a lifelong disease and its prevalence in older adults continues to increase as the population ages."( Kalb, RE; Shary, N, 2020)
"Psoriasis is an immune-mediated inflammatory disease in which the Th17 pathway is mainly involved."( Castex-Rizzi, N; Cousy, A; Lestienne, F; Mengeaud, V; Nguyen, T, 2020)
"Psoriasis is a common inflammatory skin disease."( Chen, YF; Liu, SG; Luo, GP; Qu, YB, 2020)
"Psoriasis is a severe disease associated with the disturbance of metabolism and inflammation, but the molecular mechanisms underlying these aspects of psoriasis pathology are poorly understood."( Cao, G; Deng, L; Gao, Y; Guo, C; Hao, J; Li, P; Li, Z; Song, Y; Sun, G; Tian, Y; Wang, X; Xia, X; Yin, Z; Zhang, H; Zhong, J; Zhou, W; Zhu, L, 2020)
"Introduction: Psoriasis is a chronic, immune-mediated skin disease that is associated with sex-related differences."( Cook-Bolden, FE; Guenthner, ST; Hebert, AA; Jacobson, A; Kang, R; Martin, G, 2020)
"Psoriasis is a common skin inflammatory disease."( Cai, S; Chen, H; Chen, L; Dong, L; Gong, F; Li, B; Li, J; Mao, J; Qian, Y; Shi, J; Tan, Z; Xiao, Y; Xu, Y; Zeng, F; Zheng, F, 2021)
"Psoriasis is a chronic, recurrent skin disease requiring long-term management."( Chen, K; Gu, H; Guo, Z; He, C; Jin, H; Li, X; Song, Y; Xiong, L; Xu, AE; Xu, J; Yang, Q; Yu, W; Zhang, J; Zhang, L; Zheng, J, 2020)
"Psoriasis is a chronic inflammatory disease affecting ~2-3% of the Australasian population."( Baker, C; Cains, GD; Dolianitis, C; Doolan, BJ; Foley, P; Koye, D; Ling, J, 2021)
"Psoriasis is linked to systemic inflammation and cardiovascular comorbidities, but studies of the underlying cellular mechanisms are lacking."( Bivik Eding, C; Enerbäck, C; Fekri, SZ; Sandin, C; Sigurdardottir, G; Verma, D, 2021)
"Psoriasis is considered as a common chronic immune-mediated skin disorder characterized by abnormal keratinocyte proliferation."( Du, J; Du, Z; Hu, J; Hu, M; Liu, Q; Xiang, Z; Zang, X; Zhang, L; Zhou, W, 2020)
"Psoriasis is associated with increased production of reactive oxygen species which leads to oxidative stress."( Garley, M; Jabłońska, E; Skrzydlewska, E; Wójcik, P; Wroński, A, 2020)
"The pathogenesis of psoriasis is still not fully understood."( Geng, Y; Li, J; Weng, Z; Wu, H; Xu, X; Zhou, X; Zhu, X, 2020)
"Psoriasis is a highly prevalent chronic dermatitis, characterized by widespread skin inflammation and spontaneous itch."( Huang, X; Mei, Z; Wang, H; Wang, W; Xiong, H; Zhao, Z, 2020)
"Psoriasis is a common chronic inflammatory skin condition manifested by T cell responses and characterized by preferential recurrence at previously inflamed sites upon withdrawal of treatment."( Cowin, AJ; Fenix, K; Grubor-Bauk, B; Kopecki, Z; Wijesundara, DK, 2020)
"Psoriasis is characterized by keratinocyte hyperproliferation."( Dang, E; Ke, Y; Lei, J; Shao, S; Shen, S; Wang, G; Yang, L; Zhang, C; Zhang, T; Zhu, Z, 2020)
"Psoriasis is a chronic, inflammatory, and multifactorial dermatosis that impairs quality of life (QoL)."( Andrianarison, M; Raharolahy, O; Rakotoarisaona, MF; Rakotonaivo, NA; Ramarozatovo, LS; Ranaivo, IM; Rapelanoro, RF; Ratovonjanahary, V; Razanakoto, NH; Sata, M; Sendrasoa, FA, 2020)
"Psoriasis is a skin disease that is accompanied by oxidative stress resulting in modification of cell components, including proteins."( Karabowicz, P; Ostrowska, H; Skrzydlewska, E; Waeg, G; Wroński, A; Zarkovic, N, 2020)
"Psoriasis is a highly prevalent inflammatory skin disease."( Chen, B; Jing, H; Kuang, Z; Li, L; Liu, J; Liu, Y; Qiu, X; Sun, T; Wang, L; Wu, D; Wu, M; Wu, W; Wu, Y; Wu, Z; Yi, S; Zhou, S, 2020)
"Psoriasis is mainly caused because of inappropriate immune responses in the epidermis."( Ampawong, S; Aramwit, P; Buaban, T; Kanjanapruthipong, T; Kengkoom, K; Muangkaew, W; Sukphopetch, P, 2020)
"Psoriasis is a common chronic inflammatory skin disease."( Chen, F; Fang, H; Gao, J; Mi, J; Qi, Q; Yang, M, 2020)
"Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferative keratinocytes and immune cell infiltration into the skin, often accompanied by itch."( Bäumer, W; Brehm, R; Bruer, G; Gutzmer, R; Kietzmann, M; Langeheine, M; Rode, K; Rossbach, K; Schaper-Gerhardt, K; Wahle, K; Werfel, T, 2020)
"Psoriasis is a chronic immune-mediated inflammatory skin disease that easily recurs and is difficult to cure."( Bian, G; Chen, Z; Deng, S; Feng, H; Li, Y; Wang, L; Wang, Y; Xie, Q; Yu, Y, 2021)
"Psoriasis is a chronic inflammatory skin disorder in humans, and the inflammatory reaction plays an important role in development and onset of psoriasis."( Fu, J; Li, P; Wang, Y; Zeng, Z; Zhang, L, 2020)
"Psoriasis is a common chronic inflammatory skin disease with 2% to 3% prevalence worldwide and a heavy social-psychological burden for patients and their families."( Dang, EL; Fu, M; Qiao, HJ; Wang, G; Xiao, CY; Zhang, C; Zhu, ZL, 2020)
"Psoriasis is a common inflammatory skin disease that starts before the age of 40 years in 3/4 cases."( Brenaut, É, 2020)
"Psoriasis is not only a chronic inflammatory skin disease but also a psychosomatic disorder."( Di, T; Guo, J; Guo, X; Li, P; Liu, Y; Meng, Y; Qi, C; Wang, Y; Zhang, L; Zhao, J, 2020)
"The diagnosis of psoriasis is mainly made by clinical examination but on some occasions according to the localization or duration of the lesions when spongiosis is more prominent, it can be challenging and may be considered as overlapping eczema."( Karadag, AS; Topaloglu Demir, F; Uzunçakmak, TK; Zemheri, E, 2021)
"Psoriasis is a chronic inflammation resulting from interactions between immunological and genetic factors."( Bieniek-Kobuszewska, M; Maciejewska-Radomska, A; Owczarczyk-Saczonek, A; Placek, W; Wojtacha, P, 2022)
"Psoriasis is a common inflammatory skin disease characterized by aberrant inflammation and epidermal hyperplasia."( Atwood, S; Chen, Z; Dai, X; Dragan, M; Greenberg, E; Gutierrez, G; Haensel, D; Han, W; Kessenbrock, K; Nguyen, Q; Pearlman, E; Shi, Y; Sun, P; Vu, R; Wu, J, 2021)
"Psoriasis is an incurable chronic inflammatory skin disorder."( Lou, F; Sun, Y; Wang, H, 2020)
"Psoriasis is an immune-mediated chronic inflammatory disease."( Chen, C; Chen, X; Hou, G; Peng, C; Ren, Y; Zeng, C, 2021)
"Psoriasis is the most prevalent inflammatory skin disorders, affecting 1-3% of the worldwide population."( Cao, S; Chen, L; He, S; Huang, Y; Lin, Z; Liu, Y; Tang, W; Yang, X; Zhu, F; Zuo, J, 2021)
"Psoriasis is a chronic inflammatory skin disease characterized by a skewed interleukin-17 immune response and dysregulated epidermal hyperproliferation and differentiation."( Hoashi, T; Kanda, N; Saeki, H; Serizawa, N, 2020)
"Psoriasis is a challenging skin disorder due to its chronicity, high rate of prevalence, disability, comorbidity and disfiguration."( Easwari, TS; Singh, A, 2021)
"Psoriasis is an immune disorder-related inflammatory skin disease."( Hayashi, M; Murayama, T; Otake, S; Otsubaki, T; Ueda, Y; Uesato, N, 2021)
"As psoriasis is an inflammatory disorder, we analyzed tissue infiltrating immune cells and cytokine production."( Chao, T; Gu, Y; He, L; Huang, R; Jia, T; Kong, E; Li, W; Liang, Y; Liu, Q; Liu, Z; Lu, L; Maeda, T; Pierre, P; Tian, S; Wang, Y; Yang, W; Zhang, L; Zhou, B, 2020)
"Psoriasis is a refractory inflammatory skin disease affecting 2 %-3 % of the world population, characterized by the infiltration and hyper-proliferation of inflammatory cells and aberrant differentiation of keratinocytes."( Bai, C; Chen, H; He, X; Huang, Z; Lei, Y; Li, Y; Liu, Z; Sheng, L; Tang, L; Tian, X; Wei, F; Xu, X; Yang, Y; Yu, B; Zhang, B; Zhou, X, 2021)
"Psoriasis is an autoimmune, inflammatory disease that needs a reliable animal model."( Badanthadka, M; D'Souza, L; Salwa, F, 2021)
"Plaque psoriasis is a chronic disease requiring long-term therapy."( Feldman, SR; Lopez-Gonzalez, L; Marchlewicz, EH; Martinez, DJ; Mendelsohn, AM; Shrady, G; Zhang, J; Zhao, Y, 2021)
"Psoriasis is a disease with a proinflammatory base, in which an increased expression of leptin, tumor necrosis factor alpha (TNF-α), interleukin (IL) IL-12/23, IL-6, is observed."( Adwent, I; Brus, R; Grabarek, BO; Kasela, T; Zawidlak-Węgrzyńska, B, 2021)
"Psoriasis is a chronic skin disease associated with T helper (Th)17-mediated inflammation."( Arima, Y; Hara, Y; Ito, M; Iwama, A; Kaibori, Y; Kamiyama, F; Kawada, A; Kitahata, K; Matsuo, K; Nagakubo, D; Nakayama, T; Oiso, N; Quan, YS; Yoshie, O, 2021)
"Psoriasis is a chronic, inflammatory disease that may differ in prevalence and clinical presentation among patients from various racial and ethnic groups."( Del Rosso, JQ; Desai, SR; Glick, B; Harris, S; Jacobson, A, 2021)
"Psoriasis is a chronic inflammatory disease associated with obesity and metabolic syndrome."( Akaslan, TÇ; Bulut, H; Gülcan, AS; Onsun, N; Sallahoglu, K; Yabacı, A, 2022)
"Psoriasis is a chronic inflammatory skin disease mediated by immunity."( Ji, WL; Kuai, L; Li, B; Luo, Y; Qu, KS; Ru, Y; Song, JK; Xing, M; Yan, XN, 2021)
"Nail psoriasis is a common and potentially debilitating condition for which no effective and safe nonsystemic therapy is currently available."( Artzi, O; Ellenbogen, E; Matz, H; Shehadeh, W; Sprecher, E, 2021)
"Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of keratinocytes and expression of pro-inflammatory cytokines in the epidermis."( Gendrisch, F; Haarhaus, B; Krieger, N; Quirin, KW; Schempp, CM; Wölfle, U, 2021)
"Psoriasis is a chronic and relapsing disorder with considerable negative effects on patients' quality of life."( Jin, M; Li, H; Li, S; Wang, H; Xu, Y, 2021)
"Psoriasis is an immune-mediated skin disease for which the crosstalk between genetic and environmental factors is responsible."( Arase, N; Fujimoto, M; Hirata, J; Inohara, H; Kishikawa, T; Kumanogoh, A; Maeda, Y; Masuda, T; Nii, T; Ogawa, K; Ohshima, S; Okada, Y; Suzuki, K; Tsuji, S; Yamamoto, K, 2021)
"Psoriasis is a chronic autoimmune skin disease characterized by hyperproliferation of keratinocytes."( Devabattula, G; Gangadevi, V; Godugu, C; Pooladanda, V; Thatikonda, S, 2021)
"Psoriasis is a chronic disease requiring long-term treatment strategies."( Gold, M; Gooderham, M; Kircik, LH; Lacour, JP; Laws, P; Liljedahl, M; Lynde, C; Mørch, MH; Sondermann, W; Thaçi, D; Warren, RB, 2021)
"Psoriasis is a chronic inflammatory skin disease."( Asano, Y; Kamata, M; Mitsui, A; Okura, I; Sato, S; Shimizu, T; Tada, Y, 2021)
"Psoriasis is a chronic inflammatory skin disease, in which the key features are epidermis hyperplasia, hyper-keratinization, leading to low drug absorption."( Cui, Y; Fei, WM; Guo, XD; Hao, YY; Liang, L; Zhang, C; Zhao, ZQ, 2021)
"Psoriasis is a chronic, immune-mediated skin disease."( Bortoletto, MC; da Costa, AC; Oyafuso, LKM; Rocha, ACL; Sanudo, A; Tomita, LY, 2022)
"Psoriasis is a long-lasting inflammatory skin disease lacking proper cure."( Chang, SH; Chen, YL; Hsieh, PS; Hsieh, PW; Hwang, TL; Korinek, M; Wu, YH, 2021)
"Scalp psoriasis is often undiagnosed or inadequately treated."( Alessandrini, A; Bruni, F; Orlando, G; Piraccini, BM; Starace, M, 2021)
"Psoriasis is a chronic inflammatory skin disease without cure."( Gago-López, N; Lagunas Arnal, C; Perez, JJ; Wagner, EF, 2021)
"Psoriasis is a clinically heterogeneous lifelong skin disease that presents in multiple forms such as plaque, flexural, guttate, pustular or erythrodermic."( Barker, JN; Mahil, SK; Raharja, A, 2021)
"Psoriasis is a life-threatening autoimmune inflammatory skin disease, triggered by T lymphocyte."( Biswasroy, P; Ghosh, G; Kar, B; Pradhan, D; Rath, G, 2021)
"Psoriasis is a chronic inflammatory disorder of the skin and is characterized by hyper-dividing keratinocytes."( Evan Prince, S; Hiraganahalli Bhaskarmurthy, D, 2021)
"Psoriasis is one of the most influential and fastest-growing inflammatory diseases of the skin."( Ding, W; Li, F; Qiu, B; Yang, C; Yu, F; Zhang, Y, 2021)
"Psoriasis is a chronic, inflammatory skin disease."( Chang, L; Fujita, Y; Hashimoto, K; Hashimoto, Y; Ishima, T; Matsue, H; Shinno-Hashimoto, H; Wei, Y, 2021)
"Psoriasis is chronic incurable skin inflammation."( Cai, MH; Chen, LL; Chen, XJ; Guo, LC; Shi, F; Wu, J; Wu, L; Zhu, HY; Zhu, WD, 2022)
"Psoriasis is a chronic inflammatory skin disease with abnormal epidermal proliferation."( Cui, Q; Dang, E; Lai, B; Li, F; Luo, W; Wang, G; Wang, N; Xiao, L; Xie, X; Zheng, Y, 2021)
"Psoriasis is a chronic and relapsing inflammatory skin disease lacking a cure that affects approximately 2% of the population."( Cabré, G; Ciruela, F; Filgaira, I; Hernando, J; Jacobson, KA; López-Cano, M; Nolen, EG; Soler, C; Tosh, DK, 2021)
"Psoriasis is a chronic, immune-mediated inflammatory skin disease, affecting approximately 2% of the general population, which can be accompanied by psoriatic arthritis (PsA)."( Pretorius, E; Roberts, TJ; Tarr, G; Venter, C; Visser, MJE, 2021)
"Psoriasis is a most common chronic autoimmune-arbitrated cutaneous inflammatory skin disorder by unclear pathogenesis."( Alavala, S; Jerald, MK; Nalban, N; Sangaraju, R; Sistla, R, 2021)
"Psoriasis is an immune-mediated skin disorder that affects populations worldwide."( Pang, M; Tang, Y; Wang, M; Wang, W; Wang, Y; Xu, Y; Yang, X, 2021)
"Psoriasis is a chronic inflammatory skin disease that is characterized by well-demarcated erythematous plaques with a silver scale."( Aylı, M; Caliskan, E; Coban, SN; Esme, P; Ugur, B, 2021)
"Psoriasis is a skin disease with autoimmune tendency, and taxifolin is an effective flavonoid with anti-inflammatory activity."( Chen, Z; Di, T; Li, P; Wang, Y; Zhai, C; Zhao, J, 2021)
"Psoriasis is a chronic inflammatory skin disease in which IL-17‒producing T helper 17 cells play a crucial role."( Bartolomaeus, T; Birukov, A; Boschmann, M; Brand, A; Clausen, BE; Dechend, R; Forslund, SK; Gimenez-Rivera, VA; Jung, R; Karbach, S; Karlsen, TV; Kelm, M; Kleinewietfeld, M; Kokolakis, G; Krause, A; Kuehne, T; Kurschus, FC; Linz, P; Luft, FC; Maifeld, A; Markó, L; Müller, DN; Philipp, S; Rakova, N; Schultheis, M; Waisman, A; Wegner, J; Wiig, H; Wilck, N; Wild, J; Wistorf, E, 2022)
"psoriasis is a chronic inflammatory skin disease."( Chen, Z; Di, T; Guo, X; Han, L; Han, X; Li, P; Lu, C; Wang, Y; Zhao, J, 2021)
"Psoriasis is a systemic immune‑mediated inflammatory disease characterized by uncontrolled keratinocyte proliferation and poor differentiation."( Ding, Z; Liu, J; Lv, M; Qian, H; Wu, L, 2021)
"Psoriasis is a chronic inflammatory skin disease prevalent in patients with chronic disease."( Han, KD; Kim, M; Lee, JH; Lee, SH, 2021)
"Psoriasis is a chronic immune-mediated disease characterized by excessive proliferation of epidermal keratinocytes and increased immune cell infiltration to the skin."( Bian, L; Blevins, M; Deng, H; Fan, B; Fujita, M; Han, G; High, W; Huang, M; Li, H; Norris, D; Wang, XJ; Yang, C; Zhang, C; Zhao, R, 2022)
"Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation and differentiation of keratinocytes."( Jiang, F; Liu, J; Lv, M; Shao, J, 2021)
"Psoriasis is an autoimmune, inflammatory and chronic skin disease in which cell growth and proliferation are increased, causing erythema, lesions and skin's peeling."( Agostini, SBN; Bernardes, MTCP; Bruschi, ML; Carvalho, FC; da Silva, JB; da Silva, LP; Novaes, RD; Pereira, GR, 2021)
"Psoriasis is a common chronic skin condition, which is an immune-related hyperproliferative disorder."( Al Salman, M; Azizpour, A; Farid, AS; Ghiasi, M; Mahmoudi, H; Taraz, M, 2021)
"Psoriasis is one of the most common chronic inflammatory diseases that is characterized by well-defined erythematous plaques, with typical histopathological findings of lymphocytic infiltration and epidermal hyperplasia."( Chan, TC; Chang, WY; Huang, WC; Krueger, JG; Lee, MS; Tsai, TF, 2021)
"While psoriasis is a Th17-mediated disease, how immune cells are affected by the modulation of cellular metabolism is not fully evaluated, either."( Fujimoto, M; Fujisawa, Y; Furuta, J; Inoue, S; Ishitsuka, Y; Koguchi-Yoshioka, H; Matsumura, Y; Matsuzaka, T; Nakamura, Y; Okiyama, N; Shimano, H; Watanabe, R, 2021)
"Psoriasis is a common autoimmune inflammatory skin disease, with no clear cause, treated with topical agents and phototherapy, conventional immunosuppressant drugs and biologic agents."( Abdel Hamid, HF; Amin, MA; Attia, SS; El-Nefiawy, NE; Fetouh, MA; Rafla, M, 2022)
"Psoriasis is a common, inflammatory autoimmune skin disease."( Estadt, SN; Gharaee-Kermani, M; Gruszka, D; Gudjonsson, JE; Kahlenberg, JM; Liu, J; Lowe, L; Reed, TJ; Theros, J; Tsoi, LC; Ward, NL; Wolf-Fortune, SJ; Xing, X, 2022)
"Psoriasis is a chronic inflammatory skin condition resulting from the dysregulation of cytokines."( Ivanic, MG; Liao, W; Thatiparthi, A; Walia, S; Wu, JJ, 2021)
"Psoriasis is a common chronic inflammatory skin disorder that causes patches of thick red skin and silvery scales and affects 1-3% of the population, which reduces patient's quality of life."( Jia, HY; Lv, SC; Tang, ZL; Xu, GW; Zhang, JF; Zhang, K, 2021)
"Psoriasis is a chronic inflammatory skin disease that presents increased expression of tumor necrosis factor α (TNFα), a proinflammatory cytokine."( Bagnato, VS; Bentley, MVLB; de Araujo, MM; Suzuki, IL, 2021)
"Psoriasis is a chronic inflammatory skin disease associated with both innate and adaptive immune responses."( Chen, C; Dai, L; Liu, J; Liu, L; Pan, Y; Sui, Q; Sun, H; Sun, L; Wen, X; You, Y; Yuan, H, 2021)
"Psoriasis is a chronic skin disease characterized by thickening and disorganization of the skin's protective barrier."( Cheah, TY; Chowdhury, SR; Goh, BH; Kong, CK; Kwan, Z; Ng, MH; Yap, WH; Yong, LC, 2021)
"Psoriasis is an inflammatory skin disease, where keratinocytes play pivotal roles in its pathogenesis."( Chen, S; Qiu, F; Wang, Z; Xi, L; Zhao, Y; Zheng, Y, 2021)
"Psoriasis is an immune cell‒mediated inflammatory disease of the skin with a mixed T helper type 1/T helper type17 cytokine environment combined with an innate immune response engaging toll-like receptors."( Amento, E; Kang, GJ; Kaur, M; Mechanic, J; Ravikumar, P; Welihinda, A; Yadav, S, 2022)
"Psoriasis is a chronic inflammatory skin disease characterized by an active dynamic interplay between immune cells and keratinocytes (KCs)."( Su, L; Tang, W; Xue, X; Yu, Y; Zhang, L; Zhang, Y, 2022)
"Psoriasis is a common chronic skin disorder characterized by keratinocyte hyperproliferation with altered differentiation accompanied by increased inflammation and angiogenesis."( Gao, J; Li, X; Ma, X; Miao, Y; Wei, W; Xi, B; Yang, C; Zhang, J; Zhou, H, 2021)
"Psoriasis is an autoimmune, chronic proliferative, inflammatory skin disease with high comorbidity."( Gupta, A; Pandey, S; Tripathi, P; Yadav, JS, 2022)
"Psoriasis is a chronic immune-mediated skin disorder."( Gao, YM; Jin, HZ; Li, F; Wang, WM; Wu, C; Yu, XL, 2021)
"Psoriasis is a chronic autoimmune-mediated skin disease manifested by patches of hyperproliferative keratinocytes that do not undergo apoptosis."( Gęgotek, A; Skrzydlewska, E; Wójcik, P; Žarković, N, 2021)
"Psoriasis is a chronic inflammatory skin disease characterized by massive keratinocyte proliferation and immune cell infiltration into the epidermis."( Chen, S; Chen, X; Cheng, H; Hua, C; Lai, L; Song, Y; Wu, X; Xu, Y; Zhu, J, 2021)
"Psoriasis is a chronic skin condition associated with interleukin-23/interleukin-17 (IL-23/IL-17) pathway."( Abdollahifar, MA; Dehpour, AR; Haddadi, NS; Hedayatyanfard, K; Kazemi, K; Shayan, M; Shokrian Zeini, M; Solaimanian, S, 2021)
"Psoriasis is a severe skin disease with significant physical and psychological health consequences."( Hu, Z; Huang, N; Li, J; Liu, X; Ma, T; Wang, Z; Wei, X; Wu, W; Zhang, J; Zhen, H; Zhou, H, 2021)
"Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperplasia and cellular infiltration."( Cai, Z; Ichii, O; Inaba, M; Kozai, M; Masum, MA; Mita, H; Takada, K; Wang, S, 2021)
"Plaque psoriasis is a common, chronic and relapsing inflammatory skin disease clinically characterized by erythema and scaling desquamation."( Augustin, M; Gold, LS; Green, LJ; Pinter, A; Praestegaard, M; Selmer, J, 2022)
"Psoriasis is related to thyroid dysfunction, especially in patients with atypical psoriasis types."( Chen, S; Du, J; Gao, L; Lin, L; Lu, X; Ma, C; Wang, R, 2021)
"While psoriasis is known as a T cell- and dendritic cell-driven skin inflammation disease, macrophages are also reported to play some roles in its development."( Alalaiwe, A; Chang, ZY; Chen, CY; Chuang, SY; Fang, JY; Sung, JT, 2021)
"Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of keratinocytes and a pro-inflammatory milieu in the skin."( Gendrisch, F; Haarhaus, B; Schempp, CM; Wölfle, U, 2021)
"Treatment of nail psoriasis is disappointing; due to poor penetrability of topical therapies and variable efficacy of systemic therapies."( Essa Abd Elazim, N; Mahmoud Abdelsalam, A; Mohamed Awad, S, 2022)
"Psoriasis is a chronic inflammatory skin disease that affects approximately 125 million people worldwide."( Guo, X; Li, Y; Zhou, J, 2021)
"Psoriasis is an auto-inflammatory skin disease characterized by abnormal activation of epidermal keratinocytes, aberrant neovascularization, and dysregulation of immune cells."( Chen, C; Chen, X; Chen, Z; Dou, X; Huang, C; Huang, H; Huang, X; Jian, X; Jiang, B; Li, Z; Liu, X; Ren, X; Shen, C; Yang, L; Yu, B; Zhong, W, 2021)
"Psoriasis is a chronic inflammatory skin disease affecting about 2-3% of the worldwide population."( Vinardell, MP, 2022)
"Psoriasis is a systemic disease that is associated with metabolic disorders, which may contribute to abnormal adipokine levels."( Fang, H; Li, C; Lu, Z; Ma, L; Shao, S; Wang, G; Xue, K, 2022)
"Psoriasis is a chronic immune-mediated skin disease with a significant impact on patients' quality of life."( Lé, AM; Torres, T, 2022)
"Psoriasis is a chronic immune-mediated inflammatory skin condition that commonly presents with red, thickened, and scaling plaques."( Fortenbach, C; Maibach, HI; Modjtahedi, BS; Motlagh, M, 2022)
"Psoriasis is a chronic multifactorial inflammatory disease that affects 3% of people worldwide."( Abdellatif, AAH; Abdulmonem, WA; Al Rugaie, O; Alhumaydhi, FA; Aljasir, M; Aljohani, ASM; AlKhowailed, MS; Alnuqaydan, AM; Alsagaby, SA; Alsuhaibani, SA; Alwashmi, ASS; Babiker, AY; Elsheikh, SY; Hegazy, AMS; Mousa, AM; Seleem, HS; Soliman, KEA; Yosof, MYR, 2022)
"Psoriasis is a chronic relapsing inflammatory skin disease that may markedly influence the patients' physical health and mental condition."( Jiang, J; Kuai, L; Li, B; Li, X; Liu, T; Luo, Y; Ru, Y; Song, J; Sun, X; Xing, M; Zhang, H, 2022)
"Psoriasis is characterized by aberrant activation of several pro-inflammatory circuits as well as abnormal hyperproliferation and dysregulated apoptosis of keratinocytes (KCs)."( Bochner, R; Fuchs-Telem, D; Gilhar, A; Keren, A; Magal, L; Malovitski, K; Nousbeck, J; Sagiv, N; Samuelov, L; Sarig, O; Sprecher, E, 2022)
"Psoriasis is a chronic inflammatory disease characterized by keratinocyte hyperproliferation and aberrant differentiation with great negative impact on patients' quality of life (QoL)."( Kumsa, SM; Tadesse, TA; Woldu, MA, 2021)
"Psoriasis is a dermatological condition often associated with systemic comorbidities such as arthritis."( Abdshah, A; Ghiasi, M; Nasimi, M; Parsaeian, M, 2022)
"Psoriasis is an immune-mediated inflammatory disease with increased risk of myocardial infarction."( Chen, M; Kapoor, P; Keel, A; Manyak, G; Mehta, NN; Osborne, MT; Pantoja, C; Parel, P; Patel, NH; Playford, MP; Rodante, JA; Scott, C; Sorokin, AV; Svirydava, M; Tawakol, A; Teague, H; Teklu, M; Zhou, W, 2021)
"Psoriasis is a psychosomatic immune skin disease with psychological factors contributing to the disease."( Di, T; Fu, J; Guo, J; Guo, X; Li, P; Liu, Q; Liu, Y; Meng, Y; Qi, C; Wang, Y; Zhang, L; Zhao, J, 2022)
"Psoriasis is a chronic inflammatory and proliferative skin disease characterized by pathological skin lesions which significantly impact the quality of life."( Abubakar, M; Challa, VS; Gangasani, JK; Naidu, VGM; Np, S; Puppala, ER; Saha, P; Sudha Yalamarthi, S; Usn, M, 2022)
"Psoriasis is a chronic, complicated, and recurrent inflammatory skin disease."( Cai, Y; Dai, Y; Li, J; Long, X; Peng, X; Shang, M; Wang, Q; Xia, C; Xian, J, 2022)
"Psoriasis is a chronic inflammatory skin disease with multiple genetic backgrounds, whose etiology and pathogenesis are still unclear."( Deng, M; Li, S; Li, X; Luo, S; Su, Y; Tan, S; Tang, G; Wu, R; Zhang, P; Zhang, Q; Zhang, S; Zhang, X; Zhao, M; Zhu, Y, 2022)
"Psoriasis is a complex chronic inflammatory skin disease with unclear molecular mechanisms."( Chen, D; Gao, J; Guo, W; Jiang, X; Ke, B; Lai, Y; Ma, H; Shao, F; Sun, Y; Wu, Z; Xu, Q; Yan, W; Zhu, Y, 2022)
"Patients with psoriasis are commonly treated with methotrexate or biologics."( Loft, N; Møller, DL; Nielsen, SD; Ostrowski, SR; Skov, L; Todberg, T, 2022)
"Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor necrosis factor-α (TNF-α) /interleukin (IL) -23/IL-17 axis, epidermal hyperproliferation, and dysregulated differentiation."( Hoashi, T; Kanda, N; Okazaki, S; Saeki, H, 2021)
"Psoriasis is an autoimmune skin disease associated with lipid metabolism."( Chen, ST; Jin, MZ; Li, B; Li, HJ; Li, X; Liu, L; Lu, Y; Luo, Y; Ru, Y; Sun, XY; Wang, J; Yang, D; Zhang, S; Zhou, YQ, 2021)
"Psoriasis is a common chronic inflammatory hypertrophic skin disease characterized by abnormal proliferation and differentiation of keratinocyte and immune T cell."( Chen, Z; Di, T; Li, P; Lv, J; Wang, Y; Xu, J; Yang, H; Zhou, T, 2022)
"Psoriasis is a common chronic immune-mediated disease that often has a serious negative impact on the physical and mental health of patients."( Chang, G; Chen, B; Li, C; Wang, H, 2022)
"Psoriasis is a chronic immune-mediated skin disorder with the nervous system contributing to its pathology."( Bai, J; Bao, L; Cai, X; Jiang, B; Li, Q; Li, X; Lou, F; Song, N; Sun, L; Sun, Y; Tang, S; Wang, B; Wang, H; Wang, Z; Wu, Y; Yin, Q; Yu, B; Zhou, H, 2022)
"Psoriasis is an autoimmune disease mediated by T cells."( Chen, X; Li, B; Li, HJ; Li, W; Li, X; Liu, L; Lu, Y; Sun, XY; Ze, K; Zhou, YQ, 2022)
"Psoriasis is a multifactorial, chronic, auto- inflammatory disease, with a worldwide prevalence of around 2%, subtended by robust genetic predisposition and autoimmune pathogenic traits."( Bernardini, N; Maddalena, P; Mambrin, A; Marchesiello, A; Marraffa, F; Potenza, C; Proietti, I; Rossi, G; Skroza, N; Tolino, E; Volpe, S, 2022)
"Psoriasis is a common chronic and recurrent disease in dermatology, which has a great impact on the physical and mental health of patients."( Ou, J; Zhang, J, 2022)
"Mild to moderate psoriasis is most often treated with topical therapy."( Frątczak, A; Lis-Święty, A, 2022)
"Psoriasis is a complex autoimmune disease that is closely associated with the disorganized pro-inflammatory polarization of macrophages and the activation of inflammatory signalling pathways."( Cui, J; Li, W; Sun, H; Zhai, S; Zhang, P; Zhao, Y, 2022)
"Psoriasis is a chronic inflammatory skin disease whose pathogenesis involves skin microbiota dysbiosis."( Chen, J; Dang, E; Fang, H; Fu, M; Li, Q; Luo, Y; Ma, J; Qiao, P; Shao, S; Wang, G; Yin, W; Yu, J; Zhang, C; Zhang, J; Zhi, D, 2022)
"Psoriasis is a common immune-mediated skin disorder manifesting in abnormal skin plaques, and phosphodiesterase 4 (PDE4) is an effective target for the treatment of inflammatory diseases such as psoriasis."( Hou, KQ; Huang, Y; Huang, YY; Liu, L; Luo, HB; Song, Z; Wan, G; Xiong, XF; Zhou, F, 2022)
"Psoriasis is a systemic inflammatory disease that is associated with increased risk of several diseases, such as psoriatic arthritis (PsA), inflammatory bowel disease, and cardiovascular diseases."( Ci, X; Du, X; Li, L; Lu, X; Luo, M; Wu, L; Xue, H, 2022)
"Psoriasis is a common inflammatory skin disorder, which can be associated with psychological disorders, such as anxiety and depression."( Choi, MJ; Nguyen, LTH; Shin, HM; Yang, IJ, 2022)
"Psoriasis is a complex chronic skin inflammatory disease characterized by abnormal proliferation, differentiation of keratinocytes and infiltration of lymphocytes and neutrophils."( Lin, X; Liu, Q; Qian, J; Tang, J; Xie, Q; Xiong, S; Zhou, Z, 2022)
"Psoriasis is an autoimmune inflammatory skin disorder consists of hyperkeratosis, abnormal keratinization, acanthosis, and infiltration of inflammatory cells in the dermis."( Jenabikordi, K; Rezaie, A; Zadeh, BSM, 2021)
"Psoriasis is a chronic skin disorder associated with multiple sequelae, such as psoriatic arthritis and cardiovascular diseases."( Cheng, H; Du, X; Li, M; Mei, X; Pan, Y; Tian, D; Yang, L; Zhang, D, 2022)
"Psoriasis is a recurrent inflammatory skin disorder characterized by epidermal hyperplasia, which is primarily driven by IL-17A."( Chen, Y; Cui, L; Dai, X; Gu, J; Guo, C; Shi, Y; Xu, H; Yu, Q; Yu, Y; Yu, Z; Zhang, X, 2022)
"Psoriasis is a skin disorder which mostly affects adults, beginning in childhood in almost one-third of patients."( Bardazzi, F; Chessa, MA; Dormi, A; Fabi, M; Filice, E; Gazzano, A; Lanari, M; Neri, I; Panizza, D; Patrizi, A; Rocca, A, 2022)
"Psoriasis is a chronic relapsing immunological skin disease characterized by multiple cross-talk inflammatory circuits which are relevantly associated with abnormal cross-reactivity between immune cells and keratinocytes (KCs)."( Chen, B; Chen, H; Chu, Z; He, Y; Lai, W; Li, Z; Ma, Y; Qian, H; Sun, J; Wang, F; Xu, J; Xu, Y, 2022)
"Psoriasis is a common immunologic chronic skin disease that affects at least 100 million individuals worldwide."( Chung, JH; Jo, SJ; Kim, EJ; Kim, SJ; Kim, TG; Lee, Y; Ohn, J; Suh, JH, 2022)
"Psoriasis is a condition of the skin which involves scales, dry patches, and inflammation."( Banga, AK; Garimella, HT; German, CL; Vora, D, 2022)
"Psoriasis is a chronic and remitting immune-related disease."( Chen, Y; Chen, Z; Guo, C; Hu, Y; Shi, Y; Wang, Y; Xu, P; Yu, Q; Yu, Z; Zhang, X; Zhao, Z; Zhou, X, 2022)
"Psoriasis is a chronic inflammatory skin disorder."( Agostini, SBN; Alves, CO; Bernardes, MTCP; Carvalho, FC; da Silva, LP; Gonçalves, RV; Novaes, RD; Pereira, GR, 2022)
"Patients with psoriasis are frequently complicated with metabolic syndrome; however, it is not fully understood how obesity and dyslipidemia contribute to the pathogenesis of psoriasis."( Akagi, T; Hiramatsu-Asano, S; Ikeda, K; Iseki, M; Ishihara, K; Kaneto, H; Morita, Y; Morizane, S; Mukai, T; Tachibana, K; Wada, J; Yahagi, A, 2022)
"Psoriasis is associated with an increased risk for cardiovascular disease (CVD)."( Deng, H; Fang, X; Guo, M; Han, L; Huang, Q; Meng, Q; Wang, B; Wu, S; Yan, K; Yang, K; Yawalkar, N; Zhang, Z; Zheng, Z; Zhu, J, 2022)
"Psoriasis is characterized by chronic skin inflammation and an aberrant pattern of keratinocyte differentiation."( Chiu, LY; Hsiao, PF; Huang, YT; Hung, CF; Lu, PH; Weng, TH; Wu, NL, 2022)
"Psoriasis is a common, chronic inflammatory skin disease associated with a large number of comorbidities."( Egeberg, A; Gyldenløve, M, 2022)
"Psoriasis is a highly inflammatory autoimmune-mediated skin disease."( Rasool, M; Srikanth, M, 2022)
"Psoriasis is a common chronic inflammatory skin disease that is prone to recurrence, and the proinflammatory factor, cysteine-rich protein 61 (Cyr61), is important in its pathophysiology."( Cheng, LY; Deng, Y; Feng, XY; Guo, DJ; Guo, WJ; Hua, L; Li, FL; Liu, X; Wang, Y; Xi, RF; Ze, K; Zhu, JY; Zhu, SJ, 2022)
"Psoriasis is a chronic, inflammatory, immune-mediated disease of the skin and joints."( Alahmadi, RA; Alamri, AM; Aljefri, YE; Alkhamisi, TA; Alkhunani, TA; Alraddadi, AA; Ghaddaf, AA, 2022)
"Psoriasis is a chronic inflammatory disease distinguished by an excessive proliferation and abnormal differentiation of keratinocytes."( Bonifaz, LC; Cancino-Diaz, JC; Cancino-Diaz, ME; Castro-Escamilla, O; Martínez-Torres, I; Perez-Tapia, SM; Rodríguez-Martínez, S; Tepale-Segura, A, 2022)
"Psoriasis is an autoimmune skin disease with an increased number of leukocytes infiltrating the dermal and epidermal compartments compared with normal skin."( Julien, P; Morin, S; Pouliot, R; Rioux, G; Simard, M, 2022)
"Psoriasis is a chronic dermal inflammatory disease with a world-wide prevalence in which different immune/non-immune cells, e."( Ahmad, SF; Al-Harbi, NO; Alanazi, AZ; Alasmari, F; Alharbi, M; Alhazzani, K; Almutairi, M; Alqahtani, F; Alqarni, SA; Ibrahim, KE; Nadeem, A, 2022)
"Psoriasis is a chronic inflammatory skin disease, which does not have effective treatment options."( Correa Atella, G; Donato-Trancoso, A; Romana-Souza, B, 2022)
"Psoriasis is an immune-mediated disease with either skin or joints manifestations, or both, and it has a major impact on quality of life."( Afach, S; Chaimani, A; Doney, L; Dressler, C; Garcia-Doval, I; Hua, C; Hughes, C; Le Cleach, L; Naldi, L; Sbidian, E, 2022)
"Psoriasis is associated with multiple comorbidities, including cardiovascular disease."( Burlando, M; Capurro, N; Carmisciano, L; Cozzani, E; Herzum, A; Oddenino, G; Parodi, A, 2022)
"(1) Background: Psoriasis is a T helper 1/T helper 17 cells-involved immune-mediated genetic disease."( Chen, LC; Cheng, YP; Guo, JW; Liu, CY, 2022)
"Psoriasis is linked to atherosclerosis."( Baloghova, J; Feketeova, E; Kolarcik, P, 2022)
"Psoriasis is a chronic skin inflammation caused by a dysfunctional immune system, which causes systemic inflammation in various organs and tissues."( Cho, H; Hwang, ES; Je, JH; Jeon, Y; Jeong, MG; Kang, J; Lee, K; Song, J, 2022)
"Psoriasis is an immune-mediated skin disease dominated by the cutaneous immune system."( Chen, XY; Landeck, L; Man, XY; Wang, P; Wang, ZY; Xu, F; Yan, BX; Zheng, M; Zhou, Y, 2022)
"Psoriasis is an immune-mediated, chronic inflammatory disease, and genetic, immune, oxidative stress (OS), and environmental factors are all thought to contribute to its occurrence."( Guo, M; Lai, R; Lei, Q; Xian, D; Xian, L; Xu, J; Yang, Y; Zhao, Y; Zhong, J, 2022)
"Psoriasis is a chronic inflammatory disease, with lesions mainly manifesting as scaly erythematous plaques."( Chen, X; Kuang, Y; Li, J; Liu, N; Liu, P; Peng, C; Yan, B; Yi, X; Zhu, W, 2022)
"Psoriasis is an autoimmune disease characterized by erythematous, scaly patches on the skin."( Kushwaha, P; Pandey, S; Shaif, M; Usmani, S, 2022)
"Psoriasis is a common skin disease with complex pathogenesis that lacks diagnostic methods."( Guo, Y; Liu, L; Wei, P; Yi, T; Zhou, X, 2022)
"Psoriasis is a chronic inflammatory autoimmune disease that is considered linked to genetic and environmental factors such as stress."( Ahangari, F; Ahangari, G; Makvand, M; Mohamadian, M; Mortazavi, H, 2022)
"Psoriasis is a chronic systemic inflammatory disease, and hyperuricemia is a common comorbidity in patients with psoriasis."( Cai, L; Li, C; Liu, X; Zhang, H; Zhang, J; Zhang, S; Zhao, Y; Zhao, Z, 2022)
"Psoriasis is a medical condition in which the skin of the body is affected at a multisytemic level."( Al-Ameedee, AA; Al-Hattab, MK; Al-Oudah, GA; Sahib, AS, 2022)
"Psoriasis is a chronic skin auto-inflammatory and systemic disorder."( Gupta, RC; Kyriakopoulos, AM; Marcinkiewicz, J; Nagl, M, 2022)
"Psoriasis is a chronic inflammatory skin disease."( Chen, Z; Gao, WQ; Hao, W; Lin, J; Tang, J; Wang, L; Xu, H; Yang, M; You, Q; Zhao, X, 2022)
"Psoriasis is a chronic noncommunicable dermatological condition, and psoriasis vulgaris is the most common phenotype."( Geng, A; Jia, B; Pei, T; Zhao, X, 2022)
"Management of scalp psoriasis is difficult, in part due to the difficulty of applying topical agents and its refractory nature."( Ghafoor, R; Goldust, M; Grabbe, S; Kircik, L; Patil, A; Weinberg, J; Yamauchi, P, 2022)
"Psoriasis is a chronic inflammatory skin disease."( Wu, X; Xiang, S; Xiang, Y, 2022)
"Psoriasis is an immune-mediated disease, with the interleukin (IL)-23/IL-17 axis currently considered its main pathogenic pathway."( Lé, AM; Puig, L; Torres, T, 2022)
"Psoriasis is a prevalent chronic inflammatory skin condition marked by immune cell infiltration and keratinocyte abnormal proliferation."( Di, T; Feng, F; Hu, X; Li, P; Meng, Y; Qi, C; Wang, Y; Zhang, X; Zhao, J; Zhao, N, 2022)
"Psoriasis is a chronic skin disease with 2-4% of prevalence worldwide conferring a major burden on health systems."( Aftab, U; Akhtar, T; Muhammad, H; Rafi, A; Salahuddin, Z; Shahzad, M; Zafar, MS, 2022)
"Psoriasis is a chronic inflammatory skin disorder related to dyslipidemia, with decreased high-density lipoprotein (HDL)."( Chen, J; He, L; Liu, L; Niu, Y; Qi, H; Qin, S; Yu, S, 2022)
"Psoriasis is a common chronic autoinflammatory/autoimmune skin disease associated with elevated pro-inflammatory cytokines."( Cai, H; Chen, X; Chen, Y; Hu, W; Hua, L; Liang, S; Lin, G; Liu, Z; Ou, Y; Sun, P; Wu, X; Yang, Z; Zhou, Y, 2022)
"Psoriasis is a chronic skin inflammatory auto-immune disorder."( Bhardwaj, P; Gupta, R; Pandey, S; Ramchandra Patil, P; Tripathi, P, 2022)
"Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient."( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022)
"Psoriasis is a chronic inflammatory disease whereby long-term disease control remains a challenge for the patients."( Cardot-Leccia, N; Duteil, L; Heim, M; Irondelle, M; Passeron, T; Rocchi, S; Tulic, MK, 2022)
"Psoriasis is characterized by increased dermal vascularity, indicating that aberrant angiogenesis is associated with the pathogenesis of psoriasis."( Egawa, S; Fukaya, S; Fukuyasu, A; Hayashi, K; Ishikawa, T; Ito, M; Kamata, M; Nagata, M; Nakajima, H; Niimura, Y; Sakurai, E; Shimizu, T; Suzuki, S; Tada, Y; Tanaka, T; Uchida, H; Watanabe, A, 2023)
"Psoriasis is an inflammatory condition associated with metabolic and cardiovascular disease."( Alavi, A; Armstrong, AW; Blauvelt, A; Fitzsimmons, R; Gelfand, JM; Gottlieb, S; Kalb, RE; Lockshin, BN; Manyak, GA; Mehta, NN; Mendelsohn, L; Noe, MH; Papadopoulos, M; Parel, P; Playford, MP; Rodante, J; Shin, DB; Syed, MN; Tyring, SK; Wan, J; Werner, TJ, 2022)
"Psoriasis is characterized by hyperproliferative keratinocytes, dilated capillaries and leukocyte infiltration."( Li, M; Liu, C; Liu, S; Lu, J; Tang, J; Zhou, X; Zhu, L, 2022)
"Psoriasis is a chronic relapsing dermatological disorder that significantly affects the patients' psychosocial well-being and quality of life (QOL)."( Ahmad Fuat, MS; Mat Yudin, Z; Mohd Zin, F; Muhammad, J, 2022)
"Psoriasis is a common inflammatory skin disease that has a great impact on patients' physical and mental health."( Chen, YJ; Dong, RJ; Kuang, YQ; Li, YY; Lu, YW; Shi, N; Wang, HM; Yang, LH, 2022)
"Psoriasis is strongly associated with insulin resistance (IR)."( Calvo-Anguiano, G; Cerda-Flores, R; Chavez-Alvarez, S; Gomez-Flores, M; Gonzalez-Gonzalez, JG; Martinez-de-Villarreal, LE; Ocampo-Candiani, J; Rodriguez-Rivera, MR; Ruiz-Herrera, C; Villarreal-Martinez, A; Villarreal-Perez, JZ, 2023)
"Nail psoriasis is a chronic nail disorder that commonly affects psoriatic patients causing severe distress despite the limited body surface area."( Barilà, D; Cattel, F; Dapavo, P; Gallo, G; Mastorino, L; Panzone, M; Quaglino, P; Ribero, S, 2022)
"Psoriasis is a serious non-communicable, chronic immune-inflammatory mediated disease affecting about 125 million people worldwide."( Liu, JL; Msafiri Makene, A, 2022)
"Psoriasis is a chronic inflammatory skin disorder accompanied by excessive keratinocyte proliferation."( Chen, W; Liu, Y; Wei, K; Yu, H; Zheng, F, 2022)
"Psoriasis is a type of chronic autoimmune-mediated inflammatory skin condition in which clinical manifestations are characterized by erythema and scaly changes, with complex pathogenesis and ease of relapse, and it is difficult to cure."( Hou, JJ; Jia, HY; Qiu, HY; Wu, Y; Zhang, MD; Zhou, ML, 2022)
"Psoriasis is a chronic inflammatory skin disease that is currently incurable and causes long-term distress to patients."( Bai, D; Cheng, X; Hao, J; Li, Q; Lu, F; Sun, T; Zhang, B; Zhang, Y, 2023)
"Psoriasis is a prevalent chronic inflammatory dermatosis, which can significantly impact life quality of patients."( Cai, R; Chen, C; Chen, L; Ye, Z; Zhang, D; Zhou, J, 2023)
"Psoriasis is considered as an inflammatory skin disease accompanied by dyslipidemia comorbidity."( Li, W; Yang, C; Yang, W, 2022)
"Psoriasis is an inflammatory skin disease of chronic recurrence mediated by the interaction between IL-17 and keratinocytes, which sustains a vicious circle of inflammation."( Duan, J; Duan, R; Gao, S; Li, J; Li, X; Ma, X; Qin, Y; Shi, R; Zhang, L; Zhao, R, 2023)
"Psoriasis is a chronic skin disorder characterized by epidermal keratinocyte hyperproliferation and inflammatory infiltration."( Huo, R; Li, H; Shen, B; Sheng, H; Shu, J; Sun, H; Sun, Y; Zhai, T; Zhang, J, 2023)
"Psoriasis is a disease of immunological origin that damages the skin and mucous membranes."( Benites, E; Carrillo, E; Heras, M, 2022)
"Psoriasis is a disease of immunological origin that damages the skin and mucous membranes."( Benites, E; Carrillo, E; Heras, M, 2022)
"Psoriasis is a disease of immunological origin that damages the skin and mucous membranes."( Benites, E; Carrillo, E; Heras, M, 2022)
"Psoriasis is a chronic inflammatory skin disease and lysophosphatidic acid (LPA) has recently been reported to contribute to its pathogenesis through keratinocyte proliferation."( Jun, HS; Khin, PP; Kim, D; Lim, OK, 2022)
"Psoriasis is a chronic inflammatory skin disease and lysophosphatidic acid (LPA) has recently been reported to contribute to its pathogenesis through keratinocyte proliferation."( Jun, HS; Khin, PP; Kim, D; Lim, OK, 2022)
"Psoriasis is a chronic inflammatory skin disease and lysophosphatidic acid (LPA) has recently been reported to contribute to its pathogenesis through keratinocyte proliferation."( Jun, HS; Khin, PP; Kim, D; Lim, OK, 2022)
"Psoriasis is a chronic, immune-mediated, skin disease with a significantly negative impact on patients' quality of life."( Estevinho, T; Lé, AM; Torres, T, 2023)
"Psoriasis is a chronic, immune-mediated, skin disease with a significantly negative impact on patients' quality of life."( Estevinho, T; Lé, AM; Torres, T, 2023)
"Psoriasis is a chronic skin disease associated with deregulated interplays between immune cells and keratinocytes."( Abram, CL; Bevilacqua, D; Cassatella, MA; Caveggion, E; Cestari, T; Constantin, G; Costa, S; De Sanctis, F; Donini, M; Dusi, S; Gasperini, S; Girolomoni, G; Lonardi, S; Lowell, CA; Pettinella, F; Rodegher, P; Scapini, P; Tagliaro, F; Ugel, S; Vermi, W; Zenaro, E, 2022)
"Psoriasis is a chronic skin disease associated with deregulated interplays between immune cells and keratinocytes."( Abram, CL; Bevilacqua, D; Cassatella, MA; Caveggion, E; Cestari, T; Constantin, G; Costa, S; De Sanctis, F; Donini, M; Dusi, S; Gasperini, S; Girolomoni, G; Lonardi, S; Lowell, CA; Pettinella, F; Rodegher, P; Scapini, P; Tagliaro, F; Ugel, S; Vermi, W; Zenaro, E, 2022)
"Psoriasis is a chronic inflammatory disease that affects over 125 million people worldwide."( Aguiar, ALR; da Silva, BN; de Aguiar Cordeiro, R; de Andrade, ARC; de Lima-Neto, RG; Lima, XTV; Maia, DCSC; Moura, SGB; Pereira, LMG; Portela, FVM; Reis, AT; Rocha, MFG; Sidrim, JJC, 2023)
"Psoriasis is a chronic inflammatory disease that affects over 125 million people worldwide."( Aguiar, ALR; da Silva, BN; de Aguiar Cordeiro, R; de Andrade, ARC; de Lima-Neto, RG; Lima, XTV; Maia, DCSC; Moura, SGB; Pereira, LMG; Portela, FVM; Reis, AT; Rocha, MFG; Sidrim, JJC, 2023)
"Psoriasis is a chronic, recurrent, and often severe skin disease which is frequently associated with metabolic disorders and increased risk of cardiovascular complications."( Damasiewicz-Bodzek, A; Nowak, A, 2022)
"Patients with psoriasis are at a higher risk of developing nonalcoholic fatty liver disease."( Asaji, M; Chang, J; Hattori, H; Higo, T; Hikoso, S; Ichi, I; Inui, H; Ito, K; Kamada, Y; Kanno, K; Koseki, M; Nishida, M; Nishihara, S; Ohama, T; Okada, T; Okuzaki, D; Omatsu, T; Ono, M; Saga, A; Saibara, T; Sakata, Y; Tanaka, K; Yamashita, S; Zhu, Y, 2022)
"Psoriasis is a chronic, immune-mediated inflammatory skin disorder."( Ahn, SH; Nguyen, LTH; Shin, HM; Yang, IJ, 2022)
"Psoriasis is a chronic immune-mediated inflammatory disease."( Chen, C; Chen, M; Chen, X; Hou, G; Kuang, Y; Li, J; Li, L; Lin, L; Liu, P; Peng, C; Su, J; Yan, B; Zhu, W, 2023)
"Psoriasis is a recurring, immune-mediated dermatological disorder."( Contri, RV; Frank, LA; Gomes, GS; Guterres, SS; Longhi, MS; Pohlmann, AR, 2023)
"Psoriasis is a chronic, inflammatory cutaneous disease."( Chenyang, W; Fushida, N; Hamaguchi, Y; Horii, M; Ikawa, Y; Kitano, T; Komuro, A; Matsushita, T; Nakabori, I; Sawada, K; Xibei, J, 2022)
"Psoriasis is a systemic immune-mediated disease associated with an increased risk of comorbidities, such as psoriatic arthritis, cardiovascular disease, metabolic syndrome, inflammatory bowel disease, psychiatric disorders, and malignancy."( Chen, Y; Jiang, Y; Shi, Y; Yu, Q, 2023)
"Psoriasis is a complex inflammatory disease, which can be triggered by the interplay among keratinocytes, various immune cells, and even dermal vascular endothelial cells."( Issa, N; Kircik, L, 2023)
"Psoriasis is a chronic recurrent inflammatory skin disease with a high risk of diabetes based on disease severity."( Cai, X; Li, B; Li, H; Li, X; Liu, L; Luo, Y; Su, Y; Sun, X; Zhou, Y, 2023)
"Plaque psoriasis is a chronic skin disease characterised by periods of remission and relapse and associated with considerable burden to patients and healthcare systems."( Beveridge, AJ; Perry, R; Rasmussen, ER; Sears, AJ, 2023)
"Psoriasis is a genetically determined, environmentally triggered, immune system-mediated autoimmune disease."( Li, K; Nandakumar, KS; Ou, J; Wang, T; Wu, H, 2023)
"Psoriasis is a chronic inflammatory disease with a multifactorial genesis."( Fabbrocini, G; Genco, L; Megna, M; Noto, M; Potestio, L, 2022)
"Psoriasis is an immune-mediated chronic inflammatory skin disorder characterized by epidermal hyperplasia and infiltration of inflammatory cells."( Cai, W; Chen, L; Chen, R; Huang, S; Jiang, X; Jiang, Y; Jiang, Z; Kou, L; Mao, P; Sun, T; Wang, M; Wang, P; Wang, R; Yao, Q; Zhang, L, 2023)
"Psoriasis is a common inflammatory skin disease recognized by the World Health Organization as "an incurable chronic, noninfectious, painful, disfiguring and disabling disease."( Chen, H; Huang, Y; Jiang, J; Jin, Z; Kong, Y; Li, L; Liu, X; Tong, Q; Wei, F; Yin, J; Zhang, Y, 2022)
"Psoriasis is a chronic inflammatory skin disease with an autoimmune component and associated with joint inflammation in up to 30% of cases."( Banfi, G; Casciano, F; Gornati, L; Granucci, F; Guerrini, R; Marzola, E; Mingozzi, F; Montico, G; Protti, G; Reali, E; Secchiero, P; Volinia, S, 2023)
"Copy: Palmoplantar psoriasis is a chronic, difficult-to-treat localized variant of psoriasis that affects the palms and soles, significantly affecting patient's quality of life."( Babalola, F; Campbell, C; Gottlieb, A; Mitchell, K; Vargas, J; Yousif, J, 2023)
"Psoriasis is a complex and chronic disease with treatment needs that may change over time, influencing patient treatment goals and expectations of efficacy."( Armstrong, A; Del Rosso, J; Han, G; Jacobson, A; Lewitt, GM, 2023)
"Psoriasis is an inflammation of the skin mediated via the IL-23/Thl17/IL-17 pathway."( Apostolopoulou, K; Bogdanos, DP; Dardiotis, E; Grammatikopoulou, MG; Mavropoulos, A; Tsiogkas, SG; Zafiriou, E, 2023)
"Psoriasis is an autoimmune disorder disease with abnormally activated T lymphocytes and thickening of the epidermis."( Cheng, G; Jin, S; Liu, W; Mi, R; Pan, W; Piao, H; Zou, M, 2023)
"Psoriasis is a chronic inflammatory skin disease characterized by epidermal gene abnormalities, epidermal barrier defects and inflammation."( Ardizzone, A; Campolo, M; Capra, AP; Casili, G; Cuzzocrea, S; Esposito, E; Filippone, A; Lanza, M; Paterniti, I; Scuderi, SA, 2023)
"Psoriasis is an inflammatory skin disease."( Bi, D; Du, H; Liu, H; Liu, P; Liu, Y; Qu, F; Tao, J; Wu, J; Xiao, W; Xie, Y; Zhang, L; Zhu, J, 2023)
"Psoriasis is a chronic inflammatory skin disease."( Árvai, K; Bender, T; Illés, A; Kósa, J; Kulisch, Á; Lakatos, P; Lengyel, Z; Mándó, Z; Papp, M; Sándor, E; Tóbiás, B, 2023)
"Psoriasis is a chronic disease; thus, topical treatment options are needed that address these barriers to use and promote long-term adherence, making satisfactory improvement of psoriasis more attainable."( Bhatia, N; Jacobson, A; Kircik, L; Lain, E, 2023)
"Psoriasis is a chronic inflammatory dermatological condition characterized by well-demarcated erythematous scaly plaques."( Galande, T; Kumar, R; Pawar, S; Sangtani, R; Sarasambi, A, 2023)
"Psoriasis is a chronic inflammatory dermatosis with an unclear pathogenesis."( Chen, H; Chen, K; Hu, Y; Huang, D; Ju, M; Liu, L; Luan, C; Zhang, J; Zhou, X, 2023)
"Psoriasis is a prevalent inflammatory skin disease characterized by excessive proliferation and abnormal differentiation of keratinocytes, and infiltration of inflammatory cells into the epidermis."( Li, J; Ren, F; Sang, H; Yan, W, 2023)
"Psoriasis is a chronic inflammatory skin disease mediated by immune and complex genetic factors."( Li, H; Li, X; Lin, N; Liu, L; Lu, Y; Luo, D; Sun, X; Wang, J; Yin, C; Zhang, M; Zhou, Y, 2023)
"Psoriasis is a chronic skin disorder characterized by a skin rash with scaly patches."( Egusa, C; Harada, K; Hayakawa, K; Maeda, T; Okubo, Y, 2023)
"Nail psoriasis is a significant challenge because of the difficulties in its diagnosis."( Yorulmaz, A, 2023)
"Although psoriasis is classified as a T cell-mediated inflammatory disease, the contribution of myeloid cells to the pathogenesis of psoriasis is not fully understood."( Cheng, D; Dong, G; Li, C; Liu, C; Shi, D; Wang, C; Wei, L; Xiong, H; Yan, F; Yang, Z; Zhang, H; Zhang, J; Zhang, Y, 2023)
"Psoriasis is a chronic inflammatory skin disease."( Chen, X; He, Y; Huang, X; Jia, H; Liu, T; Shan, W; Sun, R; Yang, Q, 2023)
"Psoriasis is an autoimmune chronic inflammatory skin disease with an unclear pathogenesis that is difficult to cure, causing serious physical and mental burdens for patients."( Jiang, Q; Wei, B; You, M; Zhou, X, 2023)
"Psoriasis is often combined with metabolic abnormalities, such as obesity and diabetes."( Cao, YC; Cui, WY; Kong, SM; Sun, XY, 2023)
"Psoriasis is a chronic inflammatory disease in which hyperproliferation of keratinocytes occurs."( Buda, P; Dąbala, M; Grabarek, BO; Kasela, T; Świder, M, 2023)
"Psoriasis is a chronic and immune-mediated skin condition characterized by pro-inflammatory cytokines and keratinocyte hyperproliferation."( Bakinowska, E; Dec, P; Gromowska, E; Gurazda, K; Kiełbowski, K; Modrzejewski, A; Ostrowski, P; Pala, B; Pawlik, A, 2023)
"Psoriasis is a systemic inflammatory disease associated with poor cholesterol efflux capacity and accelerated noncalcified coronary burden (NCB) as measured by coronary computed tomographic angiography."( Berg, AR; Florida, EM; Gelfand, JM; Gonzalez-Cantero, A; Hong, C; Joshi, A; Kapoor, P; Keel, A; Li, H; Mehta, NN; O'Hagan, R; Patel, N; Petrole, RF; Playford, MP; Rodante, J; Sorokin, AV; Teague, HL, 2023)
"Psoriasis is a common chronic inflammatory skin disease that is easy to relapse and difficult to cure."( Cai, X; Du, J; Gao, W; Gong, H; Lu, H; Xiao, H; Xu, J; Yang, Y, 2023)
"Psoriasis is an autoimmune, persistent, inflammatory skin illness that is influenced by a variety of circumstances."( Agop, AK; Ali Abd, S; Alsaffar, JMJ; Kadhem, EJ, 2022)
"Psoriasis is one of the chronic and autoimmune skin diseases."( Liu, Q; Ren, C; Wang, D; Wang, Q; Zhang, H, 2023)
"Psoriasis is a complex disease triggered by genetic, immunological, and environmental stimuli."( Liu, Q; Ren, C; Wang, D; Wang, Q; Zhang, H, 2023)
"Psoriasis is a disease that causes keratinocytes to proliferate ten times faster than normal, resulting in chronic inflammation and immune cell infiltration in the skin."( Carvalho, BG; Carvalho, FA; de Barros, NR; de Mendonça, RJ; Dokmeci, MR; Dos Santos, AG; Dos Santos, TO; Farhadi, N; Floriano, JF; Gomez, A; Guerra, NB; Herculano, RD; Jucaud, V; Kawakita, S; Khorsandi, D; Li, B; Mandal, K; Mecwan, M; Mussagy, CU; Nguyen, HT; Pegorin Brasil, GS; Peirsman, A; Perego, CH; Scontri, M; Tirpáková, Z, 2023)
"Psoriasis is an immune-mediated, chronic inflammatory disease affecting mainly the skin."( Menon, V; Mohan Raj, PS; Munisamy, M; Priyadarshini, G; Rajappa, M; Rajasekharan, A, 2023)
"Psoriasis is one of the most common dermatological disorders, characterized by increased epidermal hyperplasia and immune cell infiltration."( Al Rudaisat, M; Amanullah, M; Chen, S; Chen, X; Cheng, H; Hua, C; Liang, Q; Song, Y; van der Veen, S; Wang, X; Zhou, C, 2023)
"Psoriasis is a chronic autoinflammatory skin disease associated with multiple comorbidities, with a prevalence ranging from 2 to 3% in the general population."( Chen, L; Guo, Y; Li, C; Luo, L; Zhu, J, 2023)
"Psoriasis is a chronic inflammatory skin disorder, affecting the trunk and extensor surfaces of the limbs and scalp predominantly."( Ambrose, MM; Balamurugan, D; Chattopadhyay, A; Karuppusamy, A; Koley, M; Kumar, A; Nayak, C; Saha, S; Singh, NK, 2023)
"Psoriasis is a recurrent, life-threatening anti-inflammatory condition that affects nearly 1-3% of the global population."( Kumar, B; Sahoo, PK, 2023)
"Psoriasis is a chronic inflammatory skin disease that is characterized by clearly delineated erythema and squamous skin lesions."( Lin, J; Lin, P; Lu, YY; Shi, HY, 2023)
"Psoriasis is a chronic inflammatory skin disorder characterized by abnormal keratinocytes proliferation and multiple immune cells infiltration in the dermis and epidermis."( Chen, Y; Dai, Z; Feng, B; Han, W; Huang, H; Li, G; Li, H; Li, Q; Liu, H; Lu, Y; Su, Z; Tang, L; Wang, M; Wu, D; Yang, L; Ye, Z; Zhang, B; Zheng, G; Zhu, Y, 2023)
"Psoriasis is a common inflammatory skin disease characterized by the excessive proliferation and abnormal differentiation of keratinocytes."( Luo, F; Luo, M; Pan, Y; Peng, Y; Ran, C; Wang, B; Wang, H; Wang, L; Yan, YN; Yi, T; Zhang, Y; Zhou, R, 2023)
"Psoriasis is a chronic inflammatory disease with an established genetic background."( Abbad-Jaime de Aragon, C; Berna-Rico, E; Gonzalez-Cantero, A; Perez-Bootello, J, 2023)
"Psoriasis is a chronic inflammatory disease affecting the skin and the joints."( Campbell, JDM; Cuesta-Gomez, N; Graham, GJ; Medina-Ruiz, L, 2023)
"Psoriasis is an immune-mediated skin disease characterized by keratinocytes hyperproliferation, abnormal differentiation and inflammation."( Agrahari, K; Chanda, D; Khan, A; Mukhopadhyay, P; Sahoo, D; Singh, VK; Yadav, NP, 2023)
"Psoriasis is an immune-mediated disease with either skin or joints manifestations, or both, and it has a major impact on quality of life."( Afach, S; Chaimani, A; Garcia-Doval, I; Guelimi, R; Hua, C; Hughes, C; Kinberger, M; Le Cleach, L; Naldi, L; Sbidian, E, 2023)
"Psoriasis is a chronic inflammatory disease due to immune dysregulation that cannot be cured."( Chu, MY; Lee, CL; Liu, CT; Song, YC; Wang, CM; Yen, HR, 2024)
"Psoriasis is an autoimmune skin disease characterized by immunocyte activation, excessive proliferation, and abnormal differentiation of keratinocytes."( Li, P; Lin, Y; Liu, X; Wang, N; Xie, X; Zhang, L, 2023)
"Psoriasis is an inflammatory skin disease that is characterized by keratinocyte hyperproliferation, abnormal epidermal differentiation and dysregulated lipid metabolism."( Flamand, N; Morin, S; Pouliot, R; Rioux, G; Simard, M; Tremblay, A, 2023)
"Psoriasis is a complex chronic immunologically mediated disease that may involve skin, nails, and joints."( Chabowski, A; Dadan, J; Flisiak, I; Lewoc, M; Lukaszuk, B; Malla, H; Matwiejuk, M; Mysliwiec, H; Mysliwiec, P, 2023)
"Psoriasis is a chronic and incurable skin disorder that causes inflammation."( Chen, X; He, X; Hou, Y; Jiang, W; Li, W; Liu, M; Shen, F; Su, L; Xu, Z; Zhang, H; Zhu, Y; Zou, C, 2023)
"Psoriasis is a chronic, immune-mediated, multisystem, inflammatory dermatological condition that is persistent and relapsing."( Frey, K; Kalabalik-Hoganson, J; Nogid, A, 2023)
"Psoriasis is a chronic immune-mediated dermatologic disorder with multisystemic comorbidities, which is effectively treated with a range of prescription therapies."( Alexis, AF; Andriessen, A; Blattner, C; Glick, BP; Gold, LS; Kircik, L; Lynde, CW, 2023)
"Psoriasis is a chronic inflammatory skin condition."( Becker, M; Bezdek, S; Bieber, K; Gross, N; Gullberg, D; Gupta, Y; Hdnah, A; Ibrahim, SM; Künzel, S; Ludwig, RJ; Mousavi, S; Prüssmann, J; Sadik, CD; Sayegh, JP; Sezin, T; Vorobyev, A, 2023)
"The chronic disease psoriasis is associated with severe inflammation and abnormal keratinocyte propagation in the skin."( Chan, CI; Chen, SJ; Hseu, JH; Hseu, YC; Vadivalagan, C; Wu, PY; Yang, HL; Yen, HR, 2023)
"Psoriasis is a chronic inflammatory skin disease that is difficult to treat."( Chen, R; Gao, N; Gong, S; Huang, Y; Liu, E; Liu, L; Pan, L; Shen, H; Zhang, Y, 2023)
"Psoriasis is a skin disease presenting as erythematous lesions with accentuated proliferation of epidermal keratinocytes, infiltration of leukocytes, and dysregulated lipid metabolism."( Bélanger, S; Cortez Ghio, S; Morin, S; Pouliot, R, 2023)
"Psoriasis is a chronic skin disease, and topical sequential therapy with a combination of calcipotriol and calcipotriol betamethasone is currently approved topical treatment."( Cui, J; Deng, H; Deng, J; Han, L; Lu, C; Yan, Y; Yao, D; Ye, S; Yu, J; Yu, X; Zhang, X, 2023)
"Psoriasis is an autoimmune skin disease that often co-occurs with psychological morbidities such as anxiety and depression, and psychosocial issues also lead psoriasis patients to avoid other people."( Aji, A; Chen, T; Chu, YX; Li, FL; Wang, H; Wang, YQ; Xu, S; Zhang, C; Zhu, SJ, 2023)
"Psoriasis is a chronic inflammatory skin disease in which growth activity is more prominent than inflammatory activity at the centre of lesional skin (CE skin)."( Boonpethkaew, S; Chakkavittumrong, P; Jumlongpim, O; Juntongjin, P; Komine, M; Meephansan, J; Morita, A; Ponnikorn, S; Wongpiyabovorn, J, 2023)
"Psoriasis is an inflammatory skin disease accompanied with chronic papulosquamous lesions and multiple comorbidities that considerably affect patients' quality of life."( Chen, X; Fan, G; He, F; Li, S; Wang, Y; Yang, G; Yang, Z; Zhan, J; Zhang, L; Zhang, Y, 2023)
"Psoriasis is a deleterious auto-immune disorder which seriously harms the patients physical and mental health."( Alshehri, SA; Hazari, SA; Kesharwani, P; Molugulu, N; Sahebkar, A; Sheikh, A; Wahab, S, 2023)
"Psoriasis is a chronic autoimmune skin disease with a significant impact on quality of life and potential for severe comorbidities."( Chen, YC; Chou, TY; Li, CL; Liao, EC; Lu, LY; Shih, MC; Wang, KC; Yen, CY; Yen, LJ; Yu, SJ, 2023)
"Psoriasis is a chronic inflammatory skin disease that affects both localized and systemic regions of the body."( Bhuvarahamurthy, S; Kalaiyazhagan, A; Meganathan, J; Ramamoorthy, R; Venugopal, B; Vijayapoopathi, S, 2023)
"Psoriasis is a common and recurrent inflammatory skin disease characterized by inflammatory cells infiltration of the dermis and excessive proliferation, reduced apoptosis, and abnormal keratosis of the epidermis."( Chen, X; Fang, Z; Huang, B; Jiang, R; Wang, Y; Yin, M, 2023)
"Psoriasis is an immune-mediated inflammatory disorder of the skin, characterised by uncontrolled proliferation and dysfunctional differentiation of keratinocytes."( Karampitsakos, T; Katsaras, M; Sotiropoulou, V; Tzouvelekis, A, 2023)
"Psoriasis is a skin disease characterized by epidermal hyperplasia and an inappropriate activation of the adaptive immunity."( Dumais, E; Flamand, N; Julien, P; Morin, S; Pouliot, R; Tremblay, A, 2023)
"Psoriasis is a chronic skin disease with interleukin (IL)-17-dominated inflammation and hyperproliferation of epidermis."( Funasaka, Y; Kanda, N; Saeki, H; Yamamoto, M; Yoshida, M, 2023)
"Psoriasis is an inflammatory disease mediated by helper T (Th)17 and Th1 cells."( Han, L; Huang, Q; Ren, J; Yan, K; Yawalkar, N; Zhang, F, 2023)
"Psoriasis is a common systemic inflammatory skin disorder affecting over 60 million people globally."( An, Q; Du, G; Hao, Y; Li, W; Lu, Y; Ren, L; Wang, J; Yang, D; Yang, H; Yang, Y; Yu, M; Zhang, S; Zhang, Y, 2023)
"Psoriasis is a long-lasting skin condition characterized by redness and thick silver scales on the skin's surface."( Alimohammadi, S; Di Nardo, A; Masuda-Kuroki, K, 2023)
"Psoriasis is a chronic, complex, immunological disorder, which may lead to many different systemic complications."( Chabowski, A; Dadan, J; Flisiak, I; Lewoc, M; Lukaszuk, B; Malla, H; Matwiejuk, M; Myśliwiec, H; Myśliwiec, P, 2023)
"Psoriasis is a prevalent laborious inflammation in skin with alternate phases of remission and relapses."( El-Kayal, M; Hatem, S, 2023)
"Psoriasis is a chronic inflammatory disease characterized by skin redness, scaliness, and itching."( Goddard, WA; Han, JH; Jang, Y; Kim, JH; Kim, SK; Kim, YC; Ko, B; Kwak, SH; Lee, JE; Park, HD; You, H, 2023)
"Psoriasis is a complex disease that nowadays is considered not only a dermatosis but a kind of systemic disorder associated with many accompanying diseases."( Baran, A; Flisiak, I; Hermanowicz, JM; Nowowiejska, J; Pawlak, D; Sieklucka, B, 2023)
"Psoriasis is an auto-immune condition with high keratinocyte hyperproliferation due to lower p53 and p22 levels."( Dadwal, N; Singh, A; Singh, D, 2023)
"Psoriasis is a chronic inflammatory skin disease characterized by thickening the epidermis with erythema, scaling, and proliferation."( Askari, VR; Baradaran Rahimi, V; Golmohammadzadeh, S; Jaafari, MR; Kamali, H; Rahmanian-Devin, P; Sanei-Far, Z, 2023)
"Psoriasis is a chronic inflammatory skin disease with metabolic abnormalities serving as important contributors for pathogenesis and progression."( Chen, W; Ding, Y; Ma, R; Peng, C; Qin, H; Shi, R; Shi, Y; Wang, X; Yu, Z, 2023)
"Psoriasis is one of the common chronic inflammatory skin diseases worldwide."( Bai, J; Fu, D; Guo, Y; Hu, H; Li, J; Li, M; Qu, Z; Si, W; Song, G; Song, X; Tian, Z; Wang, K; Wu, M; Wu, X; Xu, M; Yan, D; Yang, Z; Zhou, X, 2023)
"Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide."( Gu, C; Huang, Z; Li, L; Lian, P; Lu, R; Lu, Y; Ma, C; Peng, Z; Pu, W; Ruan, B; Su, Z; Wang, H; Wang, W; Wazir, J; Wei, L; Zong, Y, 2023)

Context

ExcerptReference
"Psoriasis has been treated systemically through most of this century, originally with arsenics, which have been given up due to their carcinogenic effect."( Zachariae, H, 1976)
"Many patients whose psoriasis has been recalcitrant to conventional therapy may greatly benefit from this drug."( Ellis, CN; Goldfarb, MT; Voorhees, JJ, 1987)
"Yet psoriasis has received little attention in the recent psychiatric literature."( Gupta, AK; Gupta, MA; Haberman, HF, 1987)
"Recently, psoriasis has been shown to respond favorably to PUVA treatment, i."( Koch, HR; Lerman, S, 1981)
"Severe forms of psoriasis have been treated successfully with cyclosporine A (cyA) in Europe and North America."( Honeyman, JF; Sánchez, L; Valdés, P, 1995)
"Plaque-type psoriasis has been successfully treated with topical calcitriol, but there has been no long-term follow-up study of the safety and efficacy of this calciotropic hormone."( Bhawan, J; Chen, TC; Holick, MF; Pèrez, A; Poche, P; Raab, R; Turner, A, 1996)
"Plaque-type psoriasis has been successfully treated with oral calcitriol, but there has been no long-term follow-up on the safety and efficacy of this calciotropic hormone for psoriasis."( Chen, TC; Holick, MF; Perez, A; Raab, R; Turner, A, 1996)
"CD8 T lymphocytes."( Bunce, M; Bunker, CB; Easterbrook, PJ; Gotch, FM; Mallon, E; Newson, R; Young, D, 1998)
"Pustular psoriasis has different clinicomorphologic forms such as generalized, localized (mainly palmoplantar or acral), and annular."( Akasya, E; Baykal, C; Büyükbabani, N; Ozkaya-Bayazit, E, 2000)
"Also, psoriasis has been associated with an abnormal plasma lipid metabolism."( Ari, Z; Durkan, K; Gündüz, K; Onur, E; Tanülkü, S; Uyanik, BS, 2002)
"Psoriasis has been recognized as an immunologically mediated inflammatory skin disease that has been associated with group A, beta-haemolytic streptococcal infections."( Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Kobayashi, H; Sato, K; Takahashi, H; Takahashi, M; Tateno, M, 2002)
"Psoriasis has been shown to highly accumulate protoporphyrin IX (PpIX), but a variable distribution within plaques after fluorescence diagnosis is seen."( Ewalds, E; Gerritsen, MJ; Kleinpenning, MM; Smits, T; van de Kerkhof, PC; van Erp, PE, 2006)
"Psoriasis has not received widespread attention because, traditionally, dermatologists have not had effective treatments for moderate to severe manifestations of the disease."( Leonardi, CL, 2003)
"Scalp psoriasis has a considerable impact on the quality of life (QOL) of patients, and most patients are dissatisfied with available treatments."( Gratton, D; Kerrouche, N; Tan, J; Thomas, R; Vender, R; Villemagne, H; Wang, B, 2009)
"Patients with psoriasis have been shown to have an increased incidence of metabolic syndrome and cardiovascular disease compared with the general population."( Dann, F; Gottlieb, AB, 2009)
"Scalp psoriasis has a significant psychosocial impact on individuals affecting their quality of life."( Augustin, M; Herberger, K; Kornek, T; Radtke, MA, 2010)
"Young patients with psoriasis have increased arterial stiffness but not microvascular dysfunction compared with healthy controls."( Chan, HH; Chan, HT; Lam, KF; Tam, S; Tse, HF; Wong, RM; Yan, GH; Yeung, CK; Yiu, KH; Yue, WS, 2011)
"Therapies for psoriasis have focused not only on ameliorating the severity of the skin lesions, but also on the quality of life (QOL)."( Amaya, M; Natsume, S; Okubo, Y; Tsuboi, R; Usui, K, 2011)
"The pathogenesis of psoriasis has not been known exactly yet."( Bayramgürler, D; Bilen, N; Çekmen, MB; Kıran, R; Özdoğan, HK; Sikar Aktürk, A, 2012)
"Pustular psoriasis has been classified into localized and generalized forms."( Bebo, BF; Hsu, S; Kalb, RE; Korman, NJ; Lebwohl, MG; Robinson, A; Van Voorhees, AS, 2012)
"Psoriasis has been related to metabolic syndrome (MS)."( Caixàs, A; Carrascosa, JM; Ceperuelo-Mallafré, V; Luelmo, J; Ribera, M; Rigla, M; Romaní, J; Vendrell, J, 2013)
"Psoriasis has been related to a higher prevalence of cardiovascular risk factors."( Arias-Santiago, S; Arrabal-Polo, MA; Buendía-Eisman, A; Magro-Checa, C; Orgaz-Molina, J; Raya-Alvarez, E; Rosales-Alexander, JL, 2013)
"The study of psoriasis has historically been hampered by the lack of good animal models."( Flutter, B; Nestle, FO, 2013)
"Psoriasis has a similar prevalence in hypertensive patients as in the general population."( Bang, CN; Devereux, RB; Gottlieb, AB; Køber, L; Okin, PM; Wachtell, K, 2014)
"Patients with psoriasis have a higher risk of developing DM."( Lai, MS; Lee, MS; Lin, RY, 2014)
"Patients with psoriasis have an increased risk of cardiovascular disease (CVD) and cardiovascular death."( Brown, L; Churton, S; Korman, NJ; Shin, TM, 2014)
"Individuals with psoriasis have increased blood levels of uric acid."( Choi, HK; Han, J; Merola, JF; Qureshi, AA; Wu, S, 2015)
"Widespread psoriasis has great effects on life."( Al-Hamamy, HR; Al-Mashhadani, SA; Mustafa, IN, 2014)
"Psoriasis has been considered as a systemic disease associated with obesity, cardiovascular diseases and metabolic syndrome."( Baran, A; Flisiak, I; Jaroszewicz, J; Świderska, M, 2015)
"Plaque psoriasis has a relatively high prevalence in adolescence, resulting in a significant impact on quality of life, including social interactions."( Debarre, JM; Gooderham, M; Goodfield, M; Keddy-Grant, J; Kurvits, M; Xu, Z, 2014)
"Patients with psoriasis have an increased risk of cardiovascular disease that is partly attributable to chronic systemic inflammation."( Bauer, B; Benoit, S; Findeisen, P; Goebeler, M; Goerdt, S; Hametner, C; Ludwig-Peitsch, WK; Meyer-Schraml, H; Poppe, M; Schaarschmidt, ML; Schmid, S; Schmieder, A, 2015)
"Patients with psoriasis have increased risk of type 2 diabetes."( Gyldenløve, M; Holst, JJ; Knop, FK; Skov, L; Storgaard, H; Vilsbøll, T, 2015)
"Psoriasis has been associated with increased risk for coronary artery disease (CAD)."( Andreadou, I; Gravanis, K; Ikonomidis, I; Lekakis, J; Makavos, G; Papadavid, E; Paraskevaidis, I; Parissis, J; Pavlidis, G; Rigopoulos, D; Theodoropoulos, K; Triantafyllidi, H; Varoudi, M, 2015)
"Psoriasis has been reported to be associated with alcohol consumption."( Franck, J; Helander, A; Lonne-Rahm, SB; Nordlind, K; Stokkeland, K; Zou, L, 2015)
"Patients with psoriasis have significantly decreased serum leptin levels compared with controls."( Carsons, SE; Mounessa, J; Reiss, AB; Voloshyna, I, 2016)
"Patients with psoriasis have an increased risk of type 2 diabetes."( Gyldenløve, M; Holst, JJ; Knop, FK; Skov, L; Vilsbøll, T; Zachariae, C, 2015)
"Psoriasis has been reported to be associated with raised serum uric acid levels and gout, and uric acid has been demonstrated to mediate inflammatory pathways via secretion of pro-inflammatory chemokines."( Lai, YC; Yew, YW, 2016)
"Many patients with psoriasis have developed acute promyelocytic leukemia (APL) whereas few reports on psoriasis-associated APL were found in the published literature."( Cao, F; Ge, F; Hou, J; Li, H; Li, J; Li, L; Li, X; Liu, S; Lv, C; Su, Y; Wang, P; Wang, S; Xu, M; Zhang, Y; Zhou, J, 2016)
"Nail and scalp psoriasis have often been found to be difficult to treat, due to the poor penetration and poor compliance of topical medication."( Beroukhim, K; Danesh, M; Koo, J; Leon, A; Nguyen, CM; Wu, JJ, 2016)
"Patients with psoriasis have increased systemic inflammation and serum uric acid (SUA) levels compared with the general population."( Dikicier, BS; Erdem, T; Solak, B, 2017)
"Most people with psoriasis have limited disease that could be treated with topicals, but topical efficacy is limited by low short-term adherence."( Alinia, H; Anderson, KL; Bahrami, N; Farhangian, ME; Feldman, SR; Huang, KE; Jaros, SC; Moradi Tuchayi, S; Richardson, IM; Sandoval, LF; Smith, JA, 2017)
"Recently, psoriasis has also been linked to hepatic disorders, however underlying mechanism connecting the two are unknown."( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alanazi, KM; Alotaibi, MR; Ansari, MA; El-Sherbeeny, AM; Nadeem, A; Zoheir, KMA, 2017)
"Psoriasis has been shown to be associated with increased incidence of myocardial infarction (MI)."( Al-Mutairi, N; Shaaban, D, 2018)
"The prevalence of psoriasis has previously been reported as 11."( Lyon, CC; Marshall, C; Woodmansey, S, 2017)
"Psoriasis has been associated with metabolic syndrome and with an increased cardiovascular risk especially in patients with severe disease."( Arteaga, C; Barahona, MJ; Barriendos, N; Curcó, N; De La Barrera, O; García, M; Giménez, N; Prat, C; Vives, P; Yordanov, S, 2018)
"Psoriasis has also been shown to be associated with kidney disease in several studies."( Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alotaibi, MR; AlSaad, AM; Ansari, MA; Nadeem, A, 2017)
"Psoriasis has been accepted as a systemic disease and it is known to be associated with various disorders including metabolic syndrome."( Artüz, F; Köktürk, F; Külcü Çakmak, S; Tamer, E; Yilmaz, E, 2017)
"Psoriasis has been shown to be associated with an increased prevalence of comorbid major depression."( Ahmad, SF; Al-Harbi, NO; Attia, SM; El-Sherbeeny, AM; Fardan, AS; Ibrahim, KE; Nadeem, A, 2017)
"Patients with psoriasis have diverse needs and different preferences for topical treatment."( Hong, CH; Lophaven, KW; Papp, KA; Philipp, S; Skallerup, P, 2017)
"Patients with psoriasis have an increased risk of myocardial infarction, and psoriasis is now recognized as an independent risk factor for coronary heart disease and cardiovascular mortality."( Berstein, G; Correa-da Rosa, J; Fitz, LJ; Garcet, S; Kim, J; Krueger, JG; Lee, J; Lowes, MA; Suarez-Farinas, M; Tomalin, L; Valdez, H; Wolk, R, 2018)
"Various studies in psoriasis have already shown peripheral blood lymphopenia during oral FAE therapy."( Dissemond, J; Huptas, L; Klode, J; Körber, A; Leister, L; Rompoti, N; Sondermann, W, 2017)
"Traditionally, psoriasis has been regarded as a disease affecting only the skin and joints."( Hu, SC; Lan, CE, 2017)
"Pediatric psoriasis has profound effects on both physical and psychosocial health of the patient."( Chen, Z; Shi, Y; Subedi, S; Yu, Q, 2018)
"Psoriasis has been related to a large number of cardiovascular risk factors such as hypertension, diabetes mellitus and arteriosclerosis."( Arias-Santiago, S; Blasco-Morente, G; Martinez-Lopez, A; Perez-Lopez, I; Tercedor-Sanchez, J, 2018)
"The treatment for psoriasis has dramatically changed over the last 10 years with the introduction of biologics."( Iwatsuki, K; Katayama, N; Morizane, S; Motoki, T; Omori, M; Sugimoto, S, 2018)
"Plaque psoriasis has significant impact on patients' quality of life."( Bewley, AP; Calzavara-Pinton, PG; Hansen, JB; Nyeland, ME; Shear, NH; Signorovitch, J, 2019)
"Psoriasis has become a topic of global concern because of consistency in its prevalence according to Global Report on Psoriasis 2016, however, till date, no therapy has provided complete cure of this disease and no useful measure was discovered to prevent it or eliminate the risk of its relapse."( Afroz, S; Khan, RA; Siddiqui, DE, 2019)
"Patients with psoriasis have a growing interest in managing their disease through diet."( Feldman, SR; Haidari, W; Kolli, SS; Pona, A, 2019)
"Patients with psoriasis have an increased risk of coronary artery disease (CAD) but data on coronary calcium score (CCS) and cardiac computed tomography angiography (CCTA) are inconsistent."( Abdulla, J; Hansen, PR; Henningsen, KMA; Kaiser, H; Skov, L, 2019)
"Patients with psoriasis have a higher prevalence of subclinical CAD, a higher burden of the disease, and more high-risk coronary plaques compared with controls without psoriasis."( Abdulla, J; Hansen, PR; Henningsen, KMA; Kaiser, H; Skov, L, 2019)
"Most patients with psoriasis have limited disease that should be manageable with topical treatment."( Cardwell, LA; Cline, AE; Feldman, SR; Okwundu, N; Richardson, IM, 2020)
"Psoriasis has been associated with ∼30% increased risk of developing type 2 diabetes (T2D), with numerous studies reporting that psoriasis is an independent risk-factor for T2D, separate from underlying obesity."( Brain, SD; Caton, PW; Evans, EA; Frame, J; Hannen, RF; Kodji, X; Philpott, MP; Rizvi, A; Sayers, SR; Shaikh, M; Xia, Y, 2020)
"Psoriasis has a negative impact in the quality of life in Malagasy patients with psoriasis, especially in younger and single patients."( Andrianarison, M; Raharolahy, O; Rakotoarisaona, MF; Rakotonaivo, NA; Ramarozatovo, LS; Ranaivo, IM; Rapelanoro, RF; Ratovonjanahary, V; Razanakoto, NH; Sata, M; Sendrasoa, FA, 2020)
"Psoriasis has been reported to be rare in people with skin of color."( Barnabas, GA; Cristaudo, A; Dassoni, F; Dell'Anna, ML; Di Domenico, EG; Godefay, H; Latini, O; Lora, V; Lotti, T; Morrone, A; Padovese, V; Saraceni, P; Wubayehu, T, 2022)
"Patients with psoriasis have a higher risk of AIH."( Hoashi, T; Kanda, N; Saeki, H; Serizawa, N, 2020)
"Psoriasis has important physical and psychosocial effects that extend beyond the skin."( Calzavara-Pinton, P; de la Cueva, P; Gooderham, M; Jalili, A; Kircik, L; Lons-Danic, D; Nyholm, N; Petersen, B; Pink, A; Segaert, S; Thaçi, D; Thoning, H; Tyring, S, 2022)
"The pathogenesis of psoriasis has not been fully elucidated and there is no effective therapy in clinic."( Chen, Z; Di, T; Li, P; Lv, J; Wang, Y; Xu, J; Yang, H; Zhou, T, 2022)
"Nail psoriasis has a major negative impact on physical and psychological aspects of the patient's life."( Alakad, R; Atef, H; Eldeeb, F; Nassar, A, 2022)
"Psoriasis has a multifactorial pathogenesis and topical treatments are considered first line."( Feldman, SR; Singh, R; Taylor, A, 2023)
"Psoriasis has long been associated with inflammatory bowel disease (IBD); however, a causal link is yet to be established."( Daien, CI; King, NJC; Macia, L; Mielle, J; Moore, RJ; Ni, D; Pinget, GV; Simpson, S; Stanley, D; Taitz, J; Tan, JK, 2022)
"Its role in psoriasis has been not investigated so far."( Chen, JQ; Chen, XY; Cui, YZ; Fu, NC; Landeck, L; Man, XY; Wang, ZY; Xu, F; Yan, BX; Yang, XY; Zhou, Y, 2022)
"Its role in psoriasis has been not investigated so far."( Chen, JQ; Chen, XY; Cui, YZ; Fu, NC; Landeck, L; Man, XY; Wang, ZY; Xu, F; Yan, BX; Yang, XY; Zhou, Y, 2022)
"Its role in psoriasis has been not investigated so far."( Chen, JQ; Chen, XY; Cui, YZ; Fu, NC; Landeck, L; Man, XY; Wang, ZY; Xu, F; Yan, BX; Yang, XY; Zhou, Y, 2022)
"Nail psoriasis has a major negative impact on the physical and psychological aspects of the patient's life."( Abdel Raouf, NM; El Sharkawy, DA; El-Komy, MHM; Fahim, A; Sobhi, RM, 2023)

Actions

ExcerptReference
"Psoriasis affects more than 6% of Australian adults."( Cowen, P, 2001)
"furfur-positive psoriasis-affected patients, an increase in TGF-beta1, integrin chains, and HSP70 expression was found."( Agozzino, M; Baroni, A; Donnarumma, G; Paoletti, I; Ruocco, E; Tufano, MA, 2004)
"Psoriasis affects 0."( Luba, KM; Stulberg, DL, 2006)
"Plaque psoriasis affects about 2% of the US population."( Beutner, K; Chakrabarty, A; Lemke, S; Yu, K, 2006)
"Six patients with psoriasis affecting more than 10% of their body surface area and 4 controls age and sex matched to 4 of the patients with psoriasis for a nested case-control study."( Alavi, A; Antigua, J; Baer, A; Foroughi, N; Gelfand, JM; Krishnamoorthy, P; Mehta, NN; Raper, A; Saboury, B; Torigian, DA; Van Voorhees, AS; Yu, Y, 2011)
"Psoriasis affects not only the soft keratin of the skin, but also hard keratin, such as nails and hair."( Ahn, JJ; Haw, CR; Kim, KS; Kim, NI; Park, HK; Shin, MK, 2012)
"Severe nail psoriasis can impact significantly on quality of life and is difficult to treat."( Howard, A; Le, QV, 2013)
"Psoriasis affects high-density lipoprotein (HDL) composition, generating dysfunctional HDL particles."( Curcic, S; Heinemann, A; Holzer, M; Inzinger, M; Marsche, G; Pasterk, L; Trieb, M; Weger, W; Wolf, P, 2014)
"Psoriasis affecting sites such as the hands, feet and nails can be particularly difficult to treat."( Gottlieb, AB; Guettner, A; Harfst, E; Mrowietz, U; Nakayama, J; Papavassilis, C; Paul, C; Philipp, S; Reich, K, 2014)
"Psoriasis affects 2-3% of the population, causing significant morbidity and financial burden."( Fassos, I; Karra, A; Mamuris, Z; Ntoumou, E; Patsatsi, A; Roussaki-Schulze, A; Sarafidou, T; Sarri, C; Sotiriadis, D; Stamatis, C; Tsalta, A; Vasilopoulos, Y; Zafiriou, E, 2014)
"Psoriasis affects approximately 500,000 Canadians."( Daigle, D; Gupta, AK; Lyons, DC, 2014)
"Psoriasis affects an estimated 2% of the world's population, with higher rates in developed countries."( Feldman, SR; Hill, D; Kin, KC, 2016)
"Psoriasis impacts on physical and psychological well-being; improvements in health-related quality of life (HRQoL) with etanercept in psoriasis are well documented."( Mallbris, L; Mamolo, C; Papacharalambous, J; Paul, C; Tan, H; Valdez, H; Valenzuela, F, 2016)
"Psoriasis affects up to 3% of the world's population or more than 125 million people."( Anbarasu, K; Beevi, SS; Chakravdhanula, U; Verma, VK, 2016)
"Psoriasis-affected body surface area (BSA) and Psoriasis Area and Severity Index (PASI) score were used to assess severity and treatment response."( Duan, Y; Guo, D; Guo, W; Jin, W; Mao, J; Wu, M; Xu, N; Zhang, Y; Zhou, J; Zou, J, 2019)
"Psoriasis affects both sexes equally."( Akdeniz, N; Elmas, ÖF; Kızılyel, O; Metin, MS, 2019)
"Psoriasis impacts the quality of life (QoL) by disrupting overall health and social life."( Bongiorno, MR; Caruso, P; Curiale, S; Gurreri, R; Pistone, G; Tilotta, G, 2019)
"Psoriasis affects 0."( Lavaud, J; Mahé, E, 2020)
"Psoriasis affects more than 125 million people worldwide, and the diagnosis and treatment efficacy evaluation of the disease mainly rely on clinical assessments that could be subjective."( Chang, JM; Cheng, NY; Chou, SJ; Hsu, CK; Tseng, SH; Tzeng, SY; Yang, CC; Yen, YY, 2021)
"Psoriasis affects approximately 0."( Furue, M; Harada, K; Hashimoto, A; Hatano, Y; Higashi, Y; Ikeda, K; Imafuku, S; Ito, K; Kaneko, S; Katayama, E; Kikuchi, S; Koike, Y; Kuwashiro, M; Matsuzaka, Y; Miyagi, T; Morizane, S; Murota, H; Nakahara, T; Ohata, C; Ohyama, B; Okada, E; Okazaki, F; Ota, M; Saito, K; Sasaki, N; Sugita, K; Takahashi, K; Tsuruta, N; Yamaguchi, K; Yanase, T; Yonekura, K; Yoshida, Y, 2023)
"Scalp psoriasis affects most patients with psoriasis, but it can be difficult to treat."( Alonso-Llamazares, J; Berk, DR; Bhatia, N; Bukhalo, M; Burnett, P; Devani, AR; Draelos, ZD; DuBois, J; Gooderham, MJ; Higham, RC; Kempers, SE; Kircik, LH; Krupa, D; Lain, E; Lee, M; Moore, A; Murrell, DF; Papp, KA; Pariser, DM; Sinclair, R; Zirwas, M, 2023)
"Psoriasis affects diverse racial and ethnic groups."( Bhatia, N; Callender, VD; Curcio, A; Feldman, SR; Gorodokin, B; Kircik, L; Kontzias, CL; Tissera, KA, 2023)

Treatment

ExcerptReference
"Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0."( Alsins, J; Fischer, T, 1976)
"Patients treated for psoriasis with 8-MOP show concentrations of 10(-6)-10(-7) M."( Wettermark, G; Wulf, HC, 1977)
"The present study indicates, that PUVA treatment of psoriasis is not only an alternative to the use of systemic corticosteroids and cytotoxic agents but is superior to these treatment modalities due to its lack of side effects and its higher effectiveness."( Gschnait, F; Hönigsmann, H; Konrad, K; Wolff, K, 1977)
"The results of the first six months of treatment of psoriasis with photochemotherapy in the Skin and Cancer Foundation's clinic resulted in 30 out of 53 patients being completely clear of psoriasis lesions, 14 showing progressive improvement (and subsequently clearing), four failures, and five withdrawals."( King, R; O'Brien, H; Paver, K; Poyzer, K, 1979)
"The successful treatment of psoriasis with folic acid antagonists during the past 25 years has led to extensive research in the areas of cytokinetics and chemotherapy."( McCullough, JL; Weinstein, GD, 1976)
"A total of 60 patients was treated for psoriasis in a double-blind, paired comparison study of 0."( Blau, S; Kanof, NB, 1976)
"Results of treatment of psoriasis and various keratinizing dermatoses with an orally effective, aromatic retinoid are presented."( Ott, F, 1977)
"The possible methods of treating psoriasis and results obtained are reviewed and the superior effectiveness of an approach reported in recent literature, an association of methoxalene per os and broad ultraviolet rays, is pointed out."( Ormea, F, 1976)
"Azaribine is an effective agent in the treatment of psoriasis."( Cornell, RC; Fox, RM; Milstein, HG; Stoughton, RB, 1976)
"vitamin A by mouth for 38 days as a treatment for psoriasis."( Ehlers, B; Földi, E; Moeller, J, 1976)
"We report here the treatment of psoriasis, a chronic inflammatory skin disease characterized by uncontrolled keratinocyte proliferation, with BB14, a CD4 murine IgG1 antibody."( Morel, P; Nicolas, JF; Revillard, JP; Rizova, H; Thivolet, J; Wijdenes, J, 1992)
"Cyclosporine is effective in the treatment of psoriasis; however, potentially serious side effects limit its long-term use."( Goodman, MM; McCormick, A; McCullough, J; Weinstein, G; White, GM, 1992)
"During a therapeutic trial to treat psoriasis with either etretinate or cyclosporin A (CyA) we measured the respiratory burst activity of polymorphonuclear leukocytes (PMN)."( Färber, L; Höcher, J; Morsches, B; Rehder, M; Schopf, RE, 1992)
"The efficacy of home treatment of psoriasis with a new dithranol formulation, Micanol, was investigated in three studies."( Agren, S; Arlés, UB; Björnberg, A; Brolund, L; Pedersen, NB; Tegner, E; Volden, G, 1992)
"Throughout the study, untreated psoriasis plaques did not improve."( Annesley, TM; Birnbaum, JE; Burns, MK; Duell, E; Eisen, D; Ellis, CN; Griffiths, CE; Hamilton, TA; Voorhees, JJ, 1992)
"The efficacy of this treatment in psoriasis is well recognized, and the relative safety of up to 2 years of therapy is also established, provided that the guidelines are observed."( Mihatsch, MJ; Wolff, K, 1992)
"Cyclosporine A is efficacious in the treatment of psoriasis when taken orally or injected intralesionally but not topically."( Astrom, A; Duell, E; Fischer, V; Fisher, G; Voorhees, J, 1991)
"Methotrexate is effective in the treatment of severe psoriasis."( Bournerias, I, 1991)
"UVB radiation is beneficial for the treatment of psoriasis vulgaris."( Armstrong, R; Bourget, T; Edelstein, J; Lowe, NJ; Nychay, S; Prystowsky, JH, 1991)
"At the end of treatment, the psoriasis severity index decrease was 79% in the acitretin and UV-B group and 35% in the placebo and UV-B group."( Braun-Falco, O; Köster, W; Lengen, W; Lensing, W; Letzel, H; Meigel, WN; Paul, E; Przybilla, B; Ruzicka, T; Sommerburg, C, 1990)
"The present findings reveal that a pretreatment of psoriasis with topical glucocorticoids reduces the response to dithranol and the duration of remission."( Mahrle, G; Schulze, HJ, 1990)
"Dithranol is highly effective in the treatment of psoriasis."( Braun-Falco, O; Kemény, L; Ruzicka, T, 1990)
"Combined treatment of psoriasis with methotrexate and etretinate may be associated with hepatoxicity."( Jakobsen, P; Kragballe, K; Larsen, FG; Nielsen-Kudsk, F; Schrøder, H, 1990)
"The goal of therapy in the treatment of psoriasis is to decrease the rate of epidermal proliferation and the underlying inflammation."( Maibach, HI; Tung, JP, 1990)
"24 days after starting treatment of psoriasis with fumaric acid derivatives (0."( Arnholdt, H; Dalhoff, K; Faerber, P; Sack, K; Strubelt, O, 1990)
"Recently the treatment of psoriasis with vitamin D3, its metabolites or analogues, has been reported to be clinically effective and free from side effects."( Cunliffe, WJ; Holland, DB; Roberts, SG; West, MR; Wood, EJ, 1989)
"5% is an alternative in the treatment of psoriasis vulgaris on the face region as shown by bilateral comparison studies with fluocinolone acetonide 0."( Heller, G, 1989)
"In the treatment of psoriasis, which requires a stronger water-binding substance, a combination of sodium chloride and urea in equal concentrations is optimal."( Swanbeck, G, 1989)
"In the treatment of psoriasis with urea and urea-combined preparations, the individual sequence should be so clearly prescribed such that acceptance is assured."( Rohde, BT, 1989)
"Drugs used for treatment of psoriasis will sometimes cause a flare because of irritation, phototoxicity, or hypersensitivity reaction resulting in a Koebner phenomenon."( Abel, EA; DiCicco, LM; Farber, EM; Fraki, JE; Orenberg, EK, 1986)
"Oral treatment of psoriasis on an outpatient basis, using a preparation containing fumaric acid derivatives, was evaluated as initial monotherapy (3 months) and as long-term basic therapy (12-14 months) in 13 and 11 patients, respectively."( Bayard, W; Hunziker, T; Joshi, R; Krebs, A; Speiser, P, 1987)
"Like in the treatment of Psoriasis a strict correlation between the weekly administered dose and the cellular MTX could be established, the total cumulative dose, however, had no influence on the cellular MTX-level."( Dunky, A; Eberl, R; Fischer, M; Leeb, B; Ogris, E; Schenk, G; Tausch, G; Wohanka, A, 1988)
"Patients with untreated, active psoriasis had increased chemotactic response of their monocytes and neutrophils to N-formyl-methionyl-leucyl-phenylalanine."( Ternowitz, T, 1987)
"Methotrexate is frequently used in the treatment of severe psoriasis, and its hepatotoxicity has long been recognized by dermatologists."( Baker, H; Jones, DH; Phillips, TJ, 1987)
"Hydroxyurea is an effective treatment for psoriasis but consistently produces macrocytosis in peripheral blood with a fall in haemoglobin levels and white cell counts."( Comaish, JS; Dahl, MG, 1972)
"Sera from patients with untreated psoriasis were found to induce increased superoxide anion (O-2) generation when incubated with normal granulocytes (PMNs) and zymosan."( Bergstresser, PR; Hurd, ER; Sedgwick, JB, 1981)
"Current concepts in the treatment of psoriasis are reviewed, including: traditional modalities of dithranol (anthralin), tar, and corticosteroids alone or in combination with other agents; phototherapy and photochemotherapy; experimental studies with the aromatic retinoid etretinate and related analogues; dialysis; and the potential use of hyperthermia."( Farber, EM; Nall, L, 1984)
"A new preparation for treatment of psoriasis of the scalp, containing desoxymethasone 0."( Hillström, L, 1984)
"Report on the treatment of psoriasis in saturated sodium chloride water from a natural source followed by irradiation with ultraviolet UV-A- and UV-B-lights, similar to the treatment at the Dead Sea."( Ständer, M, 1983)
"In the treatment of psoriasis with topically applied methoxsalen, the patient is exposed to long-wave UV (UV-A) energy two hours after the application of methoxsalen."( Danno, K; Horio, T; Ishida, H; Toda, K, 1982)
"All patients taking methotrexate for treatment of psoriasis over the past 5 yr have been reviewed."( Ashton, RE; Millward-Sadler, GH; White, JE, 1982)
"The following treatments for psoriasis are compared with each other: PUVA, UVB, retinoid 10-9359 alone and in combination with 4 mg triamcinolone or UVB."( Schuppli, R, 1980)
"Advances in the treatment of psoriasis with anthralin are presented, including the suitability and acceptability of the base, the use of varying strengths of anthralin to suit the prevailing circumstances, and the need for showers or baths to control the treatment response."( Seville, RH, 1981)
"Patients with untreated psoriasis were less responsive than healthy controls; responses were less still in patients treated with dithranol/UV-B/tar and they were least of all in patients treated with photochemotherapy with 8-methoxypsoralen and UV-A (PUVA), particularly in those who pigmented least."( Friedmann, PS; Moss, C; Shuster, S, 1981)
"Three conventional treatments of scalp psoriasis were compared in a randomized, blind, uncontrolled clinical trial in 30 patients at a psoriasis day-care centre."( Ross, SD; Schachter, RK, 1981)
"In comparison to cyclosporine treatment of psoriasis, PUVA therapy leads to more complete reversal of pathological epidermal and lymphocytic activation, changes which we propose to be the cellular basis for a more sustained remission of disease after PUVA treatment."( Battat, L; Gilleaudeau, P; Gottlieb, AB; Heftler, N; Hodak, E; Krueger, JG; Nabeya, R; Vallat, VP; Wolfe, J, 1994)
"She had been treated for psoriasis vulgaris for 17 years without systemic immunosuppressive therapy."( Mizutani, H; Okada, H; Shimizu, M; Tanaka, H, 1995)
"Calcipotriene, a new topical treatment for psoriasis of mild to moderate severity, is a vitamin D derivative that inhibits epidermal cell proliferation in vitro."( Federman, D; Kirsner, RS, 1995)
"Topically applied capsaicin effectively treats pruritic psoriasis, a finding that supports a role for substance P in this disorder."( Berberian, B; Dodd, WA; Ellis, CN; Jarratt, MT; Katz, HI; Krueger, G; Prawer, S; Rex, IH; Sulica, VI; Wolf, JE, 1993)
"Etretinate is effective for treating psoriasis and other keratinizing disorders."( Goh, CL; Shahidullah, M; Tham, SN, 1993)
"Our studies on the treatment of psoriasis with cyclosporine A (CSA) have demonstrated efficacy at doses < 5 mg/kg/day."( Johnson, KJ; Messana, JM; Mihatsch, MJ, 1995)
"Coal tar treated psoriasis patients were used as a model population to evaluate a panel of immunoassays for monitoring exposure to benzo[a]pyrene (BP) and related polycyclic aromatic hydrocarbons (PAH)."( Beachman, A; Chiamprasert, S; DeLeo, VA; Lin, JH; Perera, FP; Santella, RM; Tang, D; Wang, LW; Young, TL; Zhang, YJ, 1995)
"Fish oil may be beneficial in the treatment of psoriasis and in RA."( Belch, JJ; Fitzsimons, C; O'Dowd, A; Richards, IM; Sturrock, RD; Torley, HI; Veale, DJ, 1994)
"Topical treatment of psoriasis with calcipotriol has been proven effective."( Berardesca, E; Distante, F; Farinelli, N; Rabbiosi, G; Vignini, M; Vignoli, GP, 1994)
"Recent advances in the treatment of psoriasis include both the topical vitamin D analogue calcipotriol and cyclosporine."( Amblard, P; Belaich, S; Claudy, A; de Belilovsky, C; de la Brassinne, M; Grossman, RM; Guilhou, JJ; Souteyrand, P; Thivolet, J; Thomas, P, 1994)
"Coal tar-treated psoriasis patients were used as a model population to test a newly developed enzyme-linked immunosorbent assay (ELISA) for urinary excretion of benzo(a)pyrene and related polycyclic aromatic hydrocarbons (PAHs)."( Beachman, A; Blaskovic, R; DeLeo, VA; Lin, JH; Nunes, MG; Perera, FP; Santella, RM; Tang, D, 1994)
"Dithranol is highly effective in the treatment of psoriasis, but the exact mechanism of action is not known."( Arenberger, P; Kemény, L; Michel, G; Ruzicka, T, 1993)
"A new topical treatment for psoriasis was introduced in 1992 when the vitamin D analogue calcipotriol was registered in Norway."( Austad, J, 1993)
"In considering specific treatment for psoriasis, cost analyses, including appropriate laboratory and other specialized evaluations, must be taken into account."( Harrison, PE; Menter, A; Morris, LF; Phillips, CM; Sander, HM, 1993)
"Therefore, in the treatment of psoriasis, therapeutic effects may be expected with liarozole which are similar to those observed with synthetic retinoids."( Decree, J; Degreef, H; Dockx, P, 1995)
"UVB phototherapy is an effective treatment for psoriasis in patients infected with HIV."( Fotiades, J; Jiang, SB; Lim, HW; Moy, J; Sanchez, M; Soter, NA, 1995)
"Topical treatment of scalp psoriasis (with corticosteroids, dithranol or tar) results in decreased scaling, induration and erythema of the plaques."( Kuijpers, AL; van Baar, HM; van de Kerkhof, PC; van Gasselt, MW, 1995)
"Its use in the treatment of psoriasis has been attempted only quite recently and some modest success achieved."( Fergin, P, 1996)
"Our findings suggest that dithranol treatment of a psoriasis plaque is associated with a decrease in oxygen radical generating capacity in vivo."( Burton, JL; Donnell, VO; Kavanagh, GM, 1996)
"The histologic response to vitamin D treatment of psoriasis includes suppression of both immune and keratinocyte activation in situ."( Gilleaudeau, P; Gottlieb, AB; Gottlieb, S; Heftler, N; Kamber, M; Krueger, JG; Lu, I; McLane, JA, 1996)
"PUVA treatment of psoriasis is usually given with broad-band fluorescent UVA lamps."( de Berker, DA; Diffey, BL; Farr, PM; Matthews, JN; Sakuntabhai, A, 1997)
"Psoralen-UVB treatment of psoriasis is as effective as conventional PUVA."( de Berker, DA; Diffey, BL; Farr, PM; Matthews, JN; Sakuntabhai, A, 1997)
"Although many other topical treatments for psoriasis (occlusive therapy and vitamin D3 analogues) result in a prominent reduction in the amount of transglutaminase and involucrin positive cell layers, the effect of dithranol on these markers is minimal."( de Jong, EM; van de Kerkhof, PC; van der Vleuten, CJ, 1996)
"It was more effective in the treatment of palmar psoriasis, whereas its greater pigmentogenic activity appeared to have an adverse effect on therapeutic effectiveness in the treatment of plaque-type psoriasis."( Calzavara-Pinton, PG; Carlino, A; De Panfilis, G; Zane, C, 1997)
"Oral retinoids are effective in the treatment of psoriasis, but their use is limited by concerns for teratogenic potential and systemic side effects."( Marks, R, 1997)
"Once daily topical treatment of psoriasis with tacalcitol ointment (4 micrograms/g) was compared with twice daily treatment with calcipotriol ointment (50 micrograms/g) in a double-blind, randomized study over a treatment period of 8 weeks."( Bjerke, JR; Jakobsen, HB; Rossmann-Ringdahl, I; Veien, NK, 1997)
"After 4 weeks out-patient treatment, the psoriasis in all patients had improved by > or = 90%."( Muchenberger, S; Schöpf, E; Simon, JC, 1997)
"Systemic treatment of psoriasis with fumaric acid esters (FAE) has been found effective by empirical means."( Altmeyer, P; Christophers, E; Mrowietz, U, 1998)
"An optimal treatment of psoriasis requires a spectrum of topical drugs and their formulations in different vehicles."( Kuipers, MV; Steegers-Theunissen, RP; van de Kerkhof, PC, 1998)
"Cyclosporine for the treatment of psoriasis constitutes a new approach."( Bos, JD; Dobozy, A; Dubertret, L; Jablonska, S; Kind, P; Rubins, A; Ruzicka, T; Zonneveld, IM, 1998)
"Systemic treatment of psoriasis with fumaric acid derivatives (FAEs) has been reported to be effective in the treatment of psoriasis, but the mode of action is still unknown."( Funk, R; Goos, M; Ockenfels, G; Ockenfels, HM; Schultewolter, T, 1998)
"Methotrexate is widely used in the treatment of severe psoriasis."( Assaraf, YG; Bergman, R; Drori, S; Friedman-Birnbaum, R; Krivoy, N; Maor, G; Reiter, I; Sprecher, E; Sprecher, H, 1998)
"We conclude that treatment of psoriasis with CyA leads to a rapid drop of blood eosinophils and that the activation state of eosinophils does not decrease after antipsoriatic treatment."( Bräutigam, M; Hultsch, T; Lotz, J; Schopf, RE, 1998)
"Thioguanine has been used to treat psoriasis, but experience is limited."( Levine, N; Silvis, NG, 1999)
"The aim of treatment in psoriasis is to reduce the degree of extension to a point compatible with the patients social, occupational and personal lifestyle."( Chiaverini, C; Desruelles, F; Lacour, JP; Ortonne, JP, 1999)
"Tazarotene shows promise as a treatment for psoriasis in special localisations, such as the scalp, face and skin folds, although clinical studies are required."( Barker, JN; Finzi, AF; Gollnick, HP; Jansen, C; Marks, R; Revuz, J; Saurat, J, 1999)
"In each case, combination treatment for psoriasis resulted in good control of both skin and joint problems using lower doses of each agent than would have been used for monotherapy."( Allen, BR; Barker, JN; Chalmers, RJ; Clark, CM; Davison, S; Emerson, R; Griffiths, CE; Kirby, B; Morris, AD; Saihan, EM; Zaki, I, 1999)
"Anthralin is a safe, effective treatment for psoriasis, but its efficacy is hampered by the side-effects of irritation and staining of the uninvolved skin."( Friedmann, PS; Parslew, R, 1999)
"Cyclosporin is an effective treatment for psoriasis but its efficacy is only palliative."( Barthélemy, H; Bressieux, JM; Jan, V; Legoux, A; Reigneau, O; Steiner, HG; Vaillant, L, 1999)
"However, oral treatment of psoriasis for 4 weeks did not result in a decrease in disease severity."( Kooijmans-Otero, ME; Mommers, JM; Parker, GL; van de Kerkhof, PC; Van Rossum, MM, 2000)
"In the treatment of psoriasis with topical vitamin D3 analogues, lesional and perilesional irritation is the main side-effect."( Lehmann, P; Neumann, NJ; Ortland, C; Ruzicka, T; Schlotmann, K, 2000)
"In the treatment of plaque psoriasis with corticosteroids, long-term efficacy and safety are often compromised by tachyphylaxis, steroid rebound, and adverse effects."( Lebwohl, M, 2000)
"As with treatment of psoriasis affecting skin, relapse is common and therapies may need to be maintained or repeated."( de Berker, D, 2000)
"betamethasone valerate 1% lotion in the treatment of psoriasis of the scalp."( Abdulla, SA; Abuzariba, O; al-Taweel, M; Duweb, GA; Rahim, M, 2000)
"The effectiveness of systemic treatment of psoriasis with fumaric acid esters has been proven, but their mode of action at the cellular and molecular level has not yet been fully elucidated."( Boorsma, DM; Flier, J; Nieboer, C; Sampat, S; Stoof, TJ; Tensen, CP, 2001)
"Out patient treatment of psoriasis is less expensive than in patient treatment."( Warin, AP, 2001)
"In the treatment of scalp psoriasis, cream formulations are used."( Franssen, ME; van de Kerkhof, PC, 2001)
"We assessed cost-effectiveness for treating psoriasis using two strategies: one consisted principally of methotrexate and the other was principally a rotational schedule of modified cyclosporine (Neoral) with methotrexate."( Bandekar, RR; Ellis, CN; Fendrick, AM; Reiter, KL, 2002)
"A method of treating psoriasis without the use of corticosteroids or antimitotic agents is described."( Comaish, S, 1965)
"It has been an established treatment for psoriasis since 1991 in Europe and 1994 in the USA."( Holm, EA; Jemec, GB, 2002)
"As we are treating selected psoriasis patients with low dose hydroxyurea we attempted to define the spectrum and chronology of dermatological adverse effects in this group of patients prospectively."( Kaur, I; Kumar, B; Saraswat, A, 2002)
"The use of cyclosporin A (CSA) for the treatment of severe psoriasis is well established."( Markham, T; Rogers, S; Watson, A, 2002)
"At the end of treatment, the psoriasis area and severity index had decreased by 57."( Green, C; Hamberg, KJ; Hutchinson, PE; Jensen, JK; Kidson, P; Kragballe, K; Larsen, FG; Munro, CS; Tillman, DM; Van de Kerkhof, PC, 2002)
"Psoralen + ultraviolet A-treated psoriasis patients are at increased risk for squamous cell carcinomas and basal cell carcinomas; however, the incidence and risk factors associated with second squamous cell carcinomas and basal cell carcinomas in this population are not well qualified."( Katz, KA; Marcil, I; Stern, RS, 2002)
"PTU may be considered as treatment model in psoriasis, in particular for resistant cases, because of its antioxidant potential, and also antiproliferative and immunomodulatory effects."( Akdaş, A; Keleştimur, F; Köse, K; Utaş, S; Yazici, C, 2002)
"Data on the efficacy of 308nm laser treatment of psoriasis were obtained from a previously published case series, supplemented by reanalysis of the data to estimate the median time to success using Kaplan-Meier methods."( Feldman, SR; Housman, TS; Mellen, BG; Rodewald, EJ, 2001)
"Body-weight-dependent (BWD) treatment of psoriasis with cyclosporine A (CsA is well established."( Bräutigam, M; Christophers, E; Kaufmann, R; Paul, C; Thaçi, D; Weidinger, G, 2002)
"In conclusion, treatment of psoriasis with cyclosporine is associated with an increased risk of nonmelanoma skin cancer."( Christophers, E; Dubertret, L; Guillaume, JC; Ho, VC; Lamarque, V; McGeown, C; Paul, CF; Schmidtmann, B, 2003)
"2 (ZHG2) in treating psoriasis with Liver-Qi stagnancy."( Luo, WH; Ouyang, H; Yang, Z, 2001)
"The effect of ZHG2 in treating psoriasis patients with Liver-Qi stagnancy is satisfactory, and worth further studying."( Luo, WH; Ouyang, H; Yang, Z, 2001)
"Many systemic agents are used in the treatment of psoriasis."( Kormeili, T; Lowe, NJ; Patnaik, R; Rizk, D; Yamauchi, PS, 2003)
"Oral retinoids are used to treat psoriasis."( Nijsten, TE; Stern, RS, 2003)
"The majority of patients treated had psoriasis that was refractory to treatment with broadband ultraviolet B, monotherapy with narrowband UVB, monotherapy with acitretin, or the combination of acitretin and broadband UVB."( Lebwohl, M; Rozenblit, M; Spuls, PI, 2003)
"Originally used to treat psoriasis nearly three decades ago, mycophenolic acid, reformulated as mycophenolate mofetil (MMF), has been rediscovered by the world of dermatology."( Liu, V; Mackool, BT, 2003)
"Vitamin D has been used for topical treatment of psoriasis, and 22-oxacalcitriol (OCT), shown to be less calcemic, was developed for the topical treatment of psoriasis in Japan."( Hashimoto, N; Higurashi, M; Hoshimoto, S; Ohigashi, S; Saito, Y; Seki, N; Tatsuno, I; Uchida, D, 2003)
"Methotrexate treatment for psoriasis is known to cause hepatic fibrosis in some patients, which might progress to cirrhosis."( Abramidou, M; Hytiroglou, P; Papadimitriou, CS; Saxena, R; Theise, ND; Tobias, H, 2004)
"Compared with other systemic treatments of psoriasis, the low cost, efficiency and well known adverse effects, are still favorable to methotrexate."( Bournerias, I, 2004)
"The efficacy of ciclosporin in the treatment of psoriasis is well established."( Ho, VC, 2004)
"To document and compare the costs of treatment of psoriasis with 2 established systemic agents that differ substantially in their unit costs: methotrexate vs cyclosporine."( Bos, JD; Bossuyt, PM; De Borgie, CA; De Rie, MA; Heydendael, VM; Opmeer, BC; Spuls, PI, 2004)
"Rational decision making for the treatment of psoriasis may include costs only within a long-term horizon and may consider the societal and patient benefits of different alternatives."( Bos, JD; Bossuyt, PM; De Borgie, CA; De Rie, MA; Heydendael, VM; Opmeer, BC; Spuls, PI, 2004)
"We aimed to develop a mechanism-based treatment for psoriasis with cyclopamine."( Avci, O; Taş, S, 2004)
"An effective treatment for psoriasis is described, consistent with intervention in a proximal/key pathogenic event."( Avci, O; Taş, S, 2004)
"Topical corticosteroids are the primary treatment for psoriasis; however, the side effects of corticosteroids are magnified on intertriginous and facial skin."( Chapman, MS; Feldman, SR; Freeman, AK; Hartle, JE; Henning, A; Lebwohl, M, 2004)
"In those patients receiving systemic treatment for psoriasis, methotrexate was the most widely used drug (4."( Boffa, MJ, 2005)
"We tried to clarify whether the treatment of plaque psoriasis as an inpatient with dithranol and narrow band UV-B 311 nm is still appropriate and economical when compared to biologics such as efalizumab."( Hahn, M; Schulz, T, 2005)
"Advances in topical treatments for psoriasis have kept pace with a rapidly evolving comprehension of its pathogenesis, making a review of current therapies useful for those who treat psoriasis."( Afifi, T; de Gannes, G; Huang, C; Zhou, Y, 2005)
"Approval for its use for the treatment of psoriasis, psoriatic arthritis and ankylosing spondylitis is expected in the near future."( Scheinfeld, N, 2005)
"Daivobet is a once-daily treatment of psoriasis vulgaris containing betamethasone dipropionate and calcipotriol in a new ointment vehicle."( Guignard, E; Ortonne, JP; Peeters, P; Sitbon, R, 2005)
"Triptolide tablet is effective for the treatment of psoriasis vulgaris during the one-year follow-up."( Guo, NR; Wu, SX, 2005)
"It is widely used for the topical treatment of psoriasis showing good tolerability and effectiveness."( Bergamin, A; Carboni, I; Chimenti, S; de Felice, C, 2005)
"Topical agents for the treatment of psoriasis are indicated for patients whose affected area is less then 10% of their skin."( Koo, JY, 2005)
"Cyslosporin A (CyA) treatment of psoriasis is warranted in severe cases where other, conventional antipsoriatic approaches have failed."( V'lckova-Laskoska, MT, 2005)
"One-month acitretin treatment reduced psoriasis activity, insulin sensitivity, evaluated as QUICKI values (0."( Angioni, R; Beck-Peccoz, P; Cattaneo, A; Corbetta, S; Spada, A, 2006)
"The topical treatment of psoriasis benefits from the alternate use of dermocorticosteroids and vitamin D3 analogues."( Delvoye, P; Flagothier, C; Henry, F; Piérard, GE; Piérard-Franchimont, C, 2005)
"There are few reports regarding the treatment of nail psoriasis with topical calcipotriol."( Barzegari, M; Mortazavi, H; Valikhani, M; Zakeri, M, 2005)
"Since treatment of psoriasis is generally long-term, the objective of this study was to investigate the efficacy and safety of transferring patients to maintenance treatment with calcipotriene cream (Dovonex cream) following a 4-week treatment period with the two-compound product."( Bibby, A; Cambazard, F; Foster, R; Haverkamp, C; Martinez Escribano, JA; Naeyaert, JM; Thaçi, D; Vender, R; White, S, 2006)
"Numerous therapies exist for the treatment of psoriasis."( Hodulik, SG; Zeichner, JA, 2006)
"The efficacy of ciclosporin in the treatment of psoriasis and atopic dermatitis has been established and clinical data also demonstrate its efficacy in treating less common but equally challenging conditions such as pyoderma gangrenosum, lichen planus, autoimmune bullous disease, recalcitrant chronic idiopathic urticaria and chronic dermatitis of the hands and feet."( Dijkmans, BA; Finlay, AY; Griffiths, CE; Ho, VC; Johnston, A; Katsambas, A; Luger, TA; Mrowietz, U; Thestrup-Pedersen, K, 2006)
"Calcipotriol has become a first-line treatment for psoriasis."( Damstra, R; de Rie, MA; de Vries, HJ; de Waard-van der Spek, FB; Haertlein, NG; Hol, CW; Kucharekova, M; Kunkeler, AC; Lijnen, RL; Oranje, AP; Swinkels, OQ; van de Kerkhof, PC; van der Valk, PG; van Hees, C; van Neer, P, 2006)
"Dithranol has been used to treat psoriasis for decades."( Dobo, E; Gulya, K; Orojan, I; Szigeti, C; Varszegi, S, 2006)
"Patients with methotrexate treated psoriasis and risk factors for liver disease, especially diabetes type 2 or overweight, are at higher risk of developing severe liver fibrosis compared to those without such risk factors, even when lower cumulative methotrexate doses are given."( Hultcrantz, R; Johannesson, A; Kinnman, N; Lindholm, J; Ros, AM; Rosenberg, P; Urwitz, H, 2007)
"Biologics in the treatment of nail psoriasis have been the subject of recent research, but their cost-effectiveness is questionable."( Berth-Jones, J; Vlachou, C, 2007)
"Conventional treatments of psoriasis include topical and systemic drugs."( Rebora, A, 2007)
"Alefacept is a biologic treatment for psoriasis, with a selective effect on memory effector T cells."( De Jong, EM; Langewouters, AM; Van De Kerkhof, PC; Van Erp, PE, 2006)
"Furthermore, she had suffered from an untreated psoriasis since the age of 20."( Albert, A; Darsow, U; Eberlein, B; Eyerich, K; Hein, R; Jakob, T; Kerzl, R; Ring, J; Rombold, S; Traidl-Hoffmann, C, 2008)
"A case of a patient who was being treated for plaque psoriasis with acitretin, who subsequently developed erythrodermic psoriasis is reported."( Ahdout, J; Chiu, M; Mandel, H, 2008)
"In the treatment of psoriasis, patient adherence to oral medications is poor and even worse for topical therapy."( Balkrishnan, R; Boles, A; Camacho, FT; Clark, A; Feldman, SR; Fleischer, AB; Makhzoumi, Z; Pearce, DJ; Yelverton, CB; Yentzer, BA, 2008)
"The choice of treatment for psoriasis in children, as in adults, is determined by disease acuity, morphology, distribution, severity, and the presence of comorbidities, such as psoriatic arthropathy."( Cordoro, KM, 2008)
"New topical treatments in scalp psoriasis are needed because many current topical treatments are disliked by patients and associated with poor compliance."( Austad, J; Berne, B; Burden, AD; de Unamuno, P; Figueiredo, A; Ganslandt, C; Jemec, GB; Ortonne, JP; Poulin, Y, 2008)
"Excimer is a useful and effective treatment for psoriasis that may be used as a compliment to topical medications as well as NB-UVB."( Gattu, S; Rashid, RM; Wu, JJ, 2009)
"Before and after treatment, psoriasis area and severity index was calculated, and serum levels of interleukin (IL)-17, IL-22, and IL-23 were investigated."( Antiga, E; Caproni, M; Del Bianco, E; Fabbri, P; Melani, L; Volpi, W, 2009)
"After treatment, psoriasis area and severity index was significantly lower for both groups."( Antiga, E; Caproni, M; Del Bianco, E; Fabbri, P; Melani, L; Volpi, W, 2009)
"Because systemic treatment of psoriasis is associated with several adverse effects, methotrexate (MTX), either topically or as targeted delivery, has become a more-interesting alternative."( Ali, MF; Rafea, M; Salah, M; Saleh, N, 2008)
"Visits to dermatologists for treatment of psoriasis were identified using National Ambulatory Medical Care Survey data, a representative survey of visits to physician offices in the United States."( Feldman, SR; Fleischer, AB; Strowd, LC; Yentzer, BA, 2009)
"The primary treatment for psoriasis in the late 1980s and early 1990s was mid-potency corticosteroids."( Feldman, SR; Fleischer, AB; Strowd, LC; Yentzer, BA, 2009)
"These indicated treatments for psoriasis and psoriatic arthritis result in suppression of the immune system."( Forman, SB; Garrett, AB; Higginson, R, 2008)
"Indigo naturalis has shown efficacy in treating psoriasis in our previous clinical studies."( Chen, HW; Leu, YL; Lin, YK; Pang, JH; Wang, CT; Yang, SH, 2009)
"Topical corticosteroids are the primary treatment for psoriasis."( Feldman, SR; Kosari, P, 2009)
"PDL seems to be effective in the treatment of nail psoriasis and improves nail matrix and nail bed involvement."( Fernández-Guarino, M; García-Morales, I; Harto, A; Jaén, P; Sánchez-Ronco, M, 2009)
"The patient has been treated for psoriasis for the past seven years, and two years ago, had to undergo surgery due to bladder carcinoma, followed by a radiotherapy course."( Dadić-Hero, E; Graovac, M; Medved, P; Ruzić, K; Torić, I, 2009)
"The use of fumaric acid esters in the treatment of psoriasis was first proposed in 1959."( Avian, A; Kokelj, F; Plozzer, C; Trevisan, G, 2009)
"TNF inhibitors have revolutionized the treatment of psoriasis vulgaris as well as psoriatic and rheumatoid arthritis and Crohn disease."( Cardinale, I; Fuentes-Duculan, J; Guttman-Yassky, E; Krueger, JG; Lowes, MA; Nograles, KE; Suárez-Fariñas, M; Zaba, LC, 2009)
"This suggests that optimal treatment of psoriasis needs to target pathogenic pathways in both leukocytes and keratinocytes."( Prens, EP; Rácz, E, 2009)
"The Goeckerman regimen (GR) for the treatment of psoriasis comprises dermal application of crude coal tar (polycyclic aromatic hydrocarbons, PAHs) and exposure to ultraviolet radiation (UVR)."( Borska, L; Cerna, M; Fiala, Z; Hamakova, K; Kremlacek, J; Kucera, I; Pelikanova, D; Smejkalova, J, 2010)
"It has been used successfully for the treatment of psoriasis and psoriatic arthritis, rheumatoid arthritis, Crohn's disease and ankylosing spondylitis either as monotherapy or in combination with drugs such as methotrexate."( Kamili, Qu; Menter, A, 2010)
"Established treatments for psoriasis are generally based on antiproliferative, anti-inflammatory, or differentiation-modifying activity, or a combination of these effects."( Anderson, RJ; Cunningham, A; Donaldson, M; George, SE; Groundwater, PW, 2010)
"Calcipotriene has limited efficacy in treating psoriasis."( Andrashko, Y; Even-Chen, Z; Gottlieb, A; Lebwohl, M; Levine, D; Lipets, I; Pritulo, OA; Svyatenko, TV, 2010)
"Acitretin is a time-honored treatment for psoriasis."( Booij, MT; Van De Kerkhof, PC, 2011)
"Finally, we treated psoriasis patients with STA-21-containing ointment in a nonrandomized study."( Asao, N; DiGiovanni, J; Iiyama, T; Ikeda, M; Kanda, T; Miyoshi, K; Nakajima, K; Sano, S; Takaishi, M; Tarutani, M, 2011)
"Tacrolimus is effective in treatment of psoriasis vulgaris."( Chen, L; Hao, F; Shen, Z; Song, Q; Tang, S; Zhong, B, 2011)
"Biological treatment of psoriasis, a chronic inflammatory immune-mediated pathology of huge social impact, has become a recent revolutionizing breakthrough in the management of the disease."( de Luca, C; Gubinelli, E; Korkina, LG; Kostyuk, VA; Lulli, D; Mariani, S; Mariani, V; Pastore, S; Pecorelli, A; Potapovich, AI; Raskovic, D; Stancato, A; Valacchi, G, 2011)
"Dimethylfumarate (DMF) is used in the treatment of psoriasis."( Gesser, B; Iversen, L; Johansen, C; Kjellerup, RB; Kragballe, K; Raaby, L; Rasmussen, MK; Rosada, C, 2011)
"Two therapies commonly used to treat psoriasis-phototherapy and tumor necrosis factor-alpha antagonists-must be used with caution in patients with both JDM and psoriasis owing to their potential to exacerbate clinical manifestations of JDM."( Jarvis, JN; Kim, NN; Lio, PA; Morgan, GA; Pachman, LM, 2011)
"Phototherapy is a mainstay in the treatment of psoriasis and is available as psoralen plus UVA (PUVA), broadband UVB (BB-UVB), and narrowband UVB (NB-UVB)."( Bagel, J; Feldman, SR; Halvorson, CR; Lapolla, W; Yentzer, BA, 2011)
"Acitretin, which is widely used in the treatment of psoriasis is part of this controversy secondary to its chemical relation to isotretinoin, a drug which has been associated with a large number of anecdotal case reports of depression and suicidal ideation."( Hayes, J; Koo, J, 2011)
"The medical records of 120 infliximab-treated psoriasis patients at our referral psoriasis clinic in Dallas between 2002-2008 were reviewed for response rates, side effects and concomitant therapies."( Hapa, A; Kamili, QU; Menter, A; Miner, A, 2011)
"Acitretin is a beneficial treatment for psoriasis, and should be considered when not contraindicated."( Dunn, LK; Feldman, SR; Gaar, LR; O'Neill, JL; Yentzer, BA, 2011)
"Etanercept is approved for the treatment of plaque psoriasis at a subcutaneous (SC) dosage of 50 mg twice-weekly for three months, followed by 50 mg SC once-weekly thereafter."( Kircik, LH, 2011)
"Methotrexate (MTX) treatment for psoriasis is most often administered weekly, because the drug has been considered more hepatotoxic when taken daily."( Moosavi, ZB; Radmanesh, M; Rafiei, B; Sina, N, 2011)
"There are few evidence-based studies on treating psoriasis in pregnant and lactating women."( Bae, YS; Bebo, B; Hsu, S; Kimball, AB; Korman, NJ; Lebwohl, MG; Van Voorhees, AS; Young, M, 2012)
"Some of these medications used to treat psoriasis are known abortifacients, mutagens, or teratogens and must be clearly avoided but others can be used with relative confidence in select patients with appropriate counseling of risks and benefits."( Bae, YS; Bebo, B; Hsu, S; Kimball, AB; Korman, NJ; Lebwohl, MG; Van Voorhees, AS; Young, M, 2012)
"Activated vitamin D3 is the first-line treatment for psoriasis."( Morimoto, S; Okuro, M, 2011)
"In the treatment of nail psoriasis, standardized therapeutic regimens are currently lacking."( Chang, YC; Chen, JL; Huang, YH; Leu, YL; Lin, YK; See, LC; Shen, YM; Tsou, TC, 2011)
"The only agent licensed for the treatment of psoriasis in patients above the age of 8 years is etanercept if classical treatment has failed."( Sticherling, M, 2012)
"An herbal drug for the treatment of psoriasis showed severe clinical adverse reactions."( He, Y; Lin, R; Lu, J; Zhang, Y, 2012)
"Methotrexate (MTX) has been used in the treatment of psoriasis."( Dayalan, H; Elango, T; Gnanaraj, P; Malligarjunan, H; Subramanian, S, 2012)
"Options for treatment of facial psoriasis, including hairline involvement, are the use of low potency topical steroids, calcineurin inhibitors, and vitamin D analogues."( Kamangar, F; Koo, JY; Nguyen, TV; Wong, JW, 2012)
"Despite recent advances in the treatment of psoriasis, the therapeutic options for nail psoriasis are very limited, particularly when this is the only manifestation of the disease."( Caldarola, G; D'Agostino, M; De Simone, C; Maiorino, A; Tassone, F, 2013)
"Only dermatologists with interest in treating psoriasis were surveyed and general perceptions were elicited via survey format."( Abuabara, K; Bebo, BF; Callis Duffin, K; Gelfand, JM; Krueger, GG; Shin, DB; Troxel, AB; Van Voorhees, AS; Wan, J, 2013)
"Photo(chemo)therapy is widely used to treat psoriasis, the pathogenesis of which might be caused by an imbalance of Th17 cells/regulatory T cells (Treg)."( Furuhashi, T; Morita, A; Nishida, E; Saito, C; Torii, K; Yamazaki, S, 2013)
"A clinical trial study in the treatment of psoriasis was conducted in twenty three patients."( Hazra, SC; Khan, SI; Khondker, L; Mahbub, MS, 2013)
"Hence, PUVAsol may be recommended as treatment for psoriasis in a developing economy such as India."( Aggarwal, K; Khandpur, S; Khanna, N; Pandav, CS; Sharma, VK, 2013)
"The successful treatment of psoriasis depends not only on the efficacy of the medication but also on patientsí acceptance and adherence to the prescribed regimen."( Anger, T; Eicke, C; Sticherling, M, 2013)
"Whether systemic treatments for psoriasis or psoriatic arthritis affect cardiovascular comorbidities is a clinically significant question."( Armstrong, AW; Armstrong, EJ; Brezinski, EA; Follansbee, MR, 2014)
"Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity."( Al-Dabagh, A; Davis, SA; Feldman, SR; Huang, K; Kinney, MA, 2013)
"Methotrexate (MTX) is a drug used to treat psoriasis due to inducing immune cell apoptosis."( Chen, C; Chen, X; Kuang, Y; Li, Q; Liu, S; Luo, Z; Su, J; Wu, L; Zeng, W; Zhang, J; Zhao, S; Zhou, S, 2013)
"The unsatisfactory outcome in the treatment of psoriasis is partially due to the poor compliance to the present therapies with more or less side-effects."( Hu, J; Li, H; Wen, C; Yang, R; Zhao, H; Zhao, M; Zhou, Q, 2013)
"Ciclosporin (Cs)A is an effective treatment for psoriasis."( Asano, Y; Kadono, T; Kamata, M; Kanda, N; Kawashima, T; Mitsui, H; Sato, S; Shibata, S; Sugaya, M; Tada, Y; Tatsuta, A; Watanabe, S, 2013)
"As part of a Cochrane review of topical treatments for psoriasis, we systematically searched electronic databases for randomized controlled trials."( Cork, MJ; Dooley, G; Hancock, H; Mason, AR; Mason, JM, 2013)
"Biological therapies for the treatment of psoriasis include targeted therapies (alefacept) and anti-cytokine therapies (anti-tumour necrosis factor [TNF] therapies [adalimumab, etanercept, infliximab] and a monoclonal antibody against interleukin [IL]-12 and IL-23 [ustekinumab])."( Costanzo, A; Papoutsaki, M, 2013)
"Methotrexate (MTX) is an effective treatment for psoriasis but concerns regarding the development of liver fibrosis prevent optimal use."( Barker, JN; Dhillon, AP; Jabbar-Lopez, ZK; Maybury, CM; Smith, CH; Wong, T, 2014)
"The upcoming systemic agents for the treatment of psoriasis are presented in this article, encompassing novel biologics and small-molecule medicines (eg, IL-17 receptor blockers, Janus kinase [Jak] inhibitors)."( Han, G, 2014)
"Topical therapy is a conventional treatment for psoriasis vulgaris."( Guo, XF; Li, G; Li, XY; Lu, CJ; Ou, AH; Wen, ZH; Xuan, ML; Yan, YH; Yao, DN, 2014)
"The frequency of systemic treatments to treat psoriasis has not significantly increased from 1993 to 2010."( Davis, SA; Feldman, SR; Fleischer, AB; Shaw, MK, 2014)
"Dermatologists and other clinicians who treat psoriasis continue to benefit from insights gained in the field of rheumatology."( Mandell, BF; Sobell, JM, 2014)
"Topical therapies are the mainstream treatment of psoriasis because most patients have mild disease."( van de Kerkhof, PC, 2015)
"Chinese herbal medicine is effective in treating psoriasis vulgaris."( Goodman, G; Lu, C; Parker, S; Wen, Z; Xue, CC; Zhang, AL; Zhang, CS, 2014)
"Current available treatments for psoriasis and melanoma are inefficient due to systemic side effects, poor transcutaneous permeation and thus present a challenge for development of novel colloidal carriers."( Divate, D; Gangurde, S; Pawar, S; Pund, S, 2015)
"MTX remains the mainstay in the treatment of psoriasis in developing countries and its combination with NBUVB offers a cheap and a beneficial therapeutic option."( Asal, M; El Desouky, F; Nofal, A; Nofal, E; Soliman, A, 2015)
"Imiquimod treatment induced a psoriasis-like skin inflammation."( Jessen, N; Kjær, TN; Pedersen, SB; Stenderup, K; Thorsen, K, 2015)
"Many biological agents, used in the treatment of psoriasis, include TFN-α inhibitors, such as etanercept, adalimumab, and anti IL-12/IL-23 p40 antibody, such as ustekinumab."( D'Amico, F; Gangemi, P; Granata, M; Longo, V; Mazzarino, MC; Mosca, A; Pettinato, M; Rossi, GA; Skarmoutsou, E; Trovato, C, 2015)
"Topical therapies are the mainstay of treatment for psoriasis vulgaris."( Hol, CW; Lambert, J; Vink, J, 2015)
"cinnamomea in the treatment of psoriasis and other Th17 cell-mediated inflammatory diseases."( Li, MH; Lin, CC; Pan, IH; Wen, SF; Wu, HC; Yao, HJ, 2015)
"Systemic treatments for psoriasis that are in the late phase of development were reviewed, with the main focus on the efficacy and adverse effects of individual treatments."( Griffiths, CE; Tan, KW, 2016)
"Four trials were identified on the treatment of psoriasis."( Bank, M; Haber, SL; Hamilton, S; Leong, SY; Pierce, E, 2016)
"Oral CHM itself appeared safe for treating psoriasis vulgaris and possibly could reduce the common adverse events seen with acitretin."( Guo, X; Lu, C; May, BH; Xue, CC; Yang, L; Yu, JJ; Zhang, AL; Zhang, CS, 2016)
"Food and Drug Administration for the treatment of psoriasis, cyclosporine has been used with great efficacy in the treatment of not only psoriasis but also a wide consortium of dermatological diseases."( Soleymani, T; Vassantachart, JM; Wu, JJ, 2016)
"Difficult-to-treat palmoplantar psoriasis has a disproportionately negative impact on quality of life."( Bissonnette, R; Chen, R; Day, RM; Goncalves, J; Pariser, DM; Sebastian, M; Wasel, NR, 2016)
"Topical treatments for psoriasis include corticosteroids, vitamin D derivatives, tazarotene, anthralin, tacrolimus, pimecrolimus, and newer formulations of tar."( Stein Gold, LF, 2016)
"Attempts to use topical cyclosporine in treatment of psoriasis have failed because of unfavorable physicochemical properties and inappropriate formulation design of the conventional dosage forms."( Amarji, B; Dogra, S; Katare, OP; Kumar, R; Kumar, S; Mahajan, R; Singh, B; Vinay, K, 2016)
"Methotrexate (MTX) has been used to treat psoriasis for over half a century."( Foerster, J; Ogston, S; West, J, 2016)
"In 2 identical, phase III studies (Oral treatment for Psoriasis Trial Pivotal 1 [NCT01276639], n = 901, and Pivotal 2 [NCT01309737], n = 960), patients were randomized 2:2:1 to receive 5 or 10 mg of tofacitinib or placebo, twice daily."( Augustin, M; Buonanno, M; de la Cruz, C; Feldman, SR; Gooderham, M; Kaur, M; Lan, S; Mallbris, L; Mamolo, C; Tatulych, S; Thaçi, D; Valdez, H, 2016)
"Difficult to treat areas of psoriasis (nail or scalp) also responded to ixekizumab."( Aoki, T; Cameron, GS; Ishii, T; Morisaki, Y; Nakagawa, H; Nakajo, K; Osuntokun, OO; Saeki, H, 2017)
"Undertreatment of psoriasis remains a problem in Belgium and more effective educational strategies are needed to ensure the best treatment outcome for these patients."( Cauwe, B; Ghislain, PD; Lambert, J; Van den Enden, M, 2017)
"Methotrexate is extensively used in the treatment of psoriasis."( Gönül, M; Hacınecipoğlu, F; Keseroglu, H, 2016)
"Psoriasis patients not taking any treatment, 3."( Ahmed, AS; Al-Najjar, AH; El-Gharabawy, RM, 2017)
"After treatment of psoriasis patients with a traditional anti-psoriatic drug in combination with metformin and peroxisome proliferator-activated receptor gamma (PPARɤ) agonist (pioglitazone), the CD4+ T cells, IL-2, CRP, CP, ALT and AST levels were statistically significantly decreased compared to psoriasis patients without treatment."( Ahmed, AS; Al-Najjar, AH; El-Gharabawy, RM, 2017)
"Methotrexate (MTX) has been used in the treatment of psoriasis and other dermatological diseases for more than 50 years."( Funding, AT; Grønbæk, H; Heickendorff, L; Heidenheim, M; Iversen, L; Kyvsgaard, N; Lindberg, R; Madsen, JT; Raaby, L; Skov, L; Strauss, G; Thielsen, P; Zachariae, C; Østensen, M, 2017)
"As methotrexate (MTX) is a widely used treatment for psoriasis, it is important to gain insight into the reasons for the discontinuation of MTX and to understand the determinants for drug survival."( de Jong, EM; Kievit, W; Otero, ME; Seyger, MM; van de Kerkhof, PC; van den Reek, JM, 2017)
"Drugs that are currently used in the treatment of psoriasis are associated with drawbacks such as rapid recrudescence, high costs and unwanted side-effects."( Bo, KP; Chen, WG; Ma, W; Shi, HJ; Song, HB; Xia, L; Yang, J; Zhou, H, 2017)
"Approaches currently available to treat psoriasis are not satisfactory due to undesirable side-effects or expense."( Chen, Q; Chi, M; Deng, X; Leavesley, D; Shi, H; Xie, N; Xie, Y; Yang, Y; Zhang, H; Zhou, H, 2017)
"Our study suggests that untreated psoriasis may impair male fertility."( Baroni, S; Caldarola, G; De Simone, C; Grande, G; Marana, R; Milardi, D; Morelli, R; Peris, K; Pontecorvi, A; Quercia, A, 2017)
"In spite of significant advances in the treatment of psoriasis, more effective and safer therapeutic strategies are still needed."( Chen, T; Fu, LX; Guo, ZP; Liu, XY; Wu, YB; Zhang, LW, 2017)
"To assess the efficacy of short-term treatment of scalp psoriasis with topical clobetasol lotion."( Feldman, SR; Firooz, A; Hasanzadeh, H; Rajabi-Estarabadi, A; Taheri, A, 2018)
"To elucidate the effect of FAE treatment on human psoriasis and healthy donor NET formation."( Enk, AH; Hadaschik, EN; Hartl, D; Hoffmann, JHO; Schaekel, K, 2018)
"Biologic and systemic drugs used to treat psoriasis can result in an increase in infections or malignancies."( Armstrong, AW; Prussick, R; Siegel, MP; Van Voorhees, AS; Wu, JJ, 2018)
"The variety of available systemic treatments for psoriasis is increasing rapidly."( Barnetche, T; Brenaut, E; Misery, L; Théréné, C, 2018)
"Most methotrexate-treated psoriasis patients do not achieve a long-term PASI75 (75% reduction from baseline Psoriasis Area and Severity Index score) response."( Betts, KA; Gordon, KB; Li, J; Okun, MM; Signorovitch, JE; Sundaram, M; Wu, EQ; Xie, M, 2017)
"Still, there are unmet needs in the treatment of psoriasis regarding long-term efficacy, tolerability, safety, route of administration, and cost."( Azevedo, A; Torres, T, 2018)
"The effectiveness of icotinib in treating psoriasis was tested in three psoriasis models, including diethylstilbestrol-treated mouse vaginal epithelial cells, mouse tail granular cell layer formation, and propranolol-induced psoriasis-like features in guinea pig ear skin."( Chen, H; Deng, Y; Ding, L; Guo, J; Huang, X; Li, H; Tan, F; Wang, Y; Yang, G; Yu, B; Yu, P, 2018)
"Many treatments for psoriasis and psoriatic arthritis are also used for IBD."( Armstrong, AW; Enos, CW; Gottlieb, A; Langley, RG; Lebwohl, M; Merola, JF; Ryan, C; Siegel, MP; Van Voorhees, AS; Weinberg, JM; Whitlock, SM; Wu, JJ, 2018)
"Apremilast is a safe and efficacious treatment for psoriasis patients as it produces ΔPASI75 and ΔPASI50 responses combined with DLQI ≤ 5 in 16 weeks in 70."( Kokkalis, G; Papadavid, E; Rigopoulos, D; Rompoti, N; Theodoropoulos, K, 2018)
"There is no evidence that treatment for psoriasis modifies leptin and adiponectin concentrations."( Goulis, DG; Kyriakou, A; Patsatsi, A; Sotiriadis, D, 2018)
"Systemic treatment of psoriasis is associated with several adverse effects, therefore the development of a customized topical treatment modality for psoriasis would be an interesting alternative to systemic delivery."( Aboel-Fadl, DM; Fadel, M; Nasr, M; Nour El-Deen, F; Ramez, SA; Soliman, MM; Youness, ER, 2018)
"The impact of ixekizumab treatment for psoriasis on cardiovascular-related parameters in patients is unknown."( Egeberg, A; Goldblum, O; Korman, N; Mallbris, L; Solomon, JA; Wu, JJ; Zhao, F, 2018)
"Methotrexate (MTX) is used to treat psoriasis, a chronic inflammatory skin disease."( Han, L; Huang, Q; Huang, Y; Ma, Y; Xin, KZ; Xu, W; Yan, K; Zhang, Z, 2018)
"Thus, DMF as monotherapy for the treatment of psoriasis is as efficacious as in combination with MEF, making the addition of such fumarate derivatives unnecessary."( Amasuno, A; Asadullah, K; Landeck, L; Mrowietz, U; Pau-Charles, I, 2018)
"Nonadherence to systemic treatments for psoriasis leads to treatment failure and increased health care utilization."( Dommasch, ED; Gagne, JJ; Garry, EM; Joyce, CJ; Lee, MP, 2018)
"The available treatments for psoriasis are not curative and may have numerous side effects, and topical administration is preferred over systemic therapy due to the reduced systemic burden of the drug."( Andreola, F; Calcaterra, A; Camponeschi, C; De Angelis, C; Giovannini, D; Nicotera, G; Pierimarchi, P; Serafino, A; Sferrazza, G; Zonfrillo, M, 2018)
"Acitretin is widely used to treat psoriasis, but the efficacy varies significantly among individuals."( Chen, W; Chen, X; Peng, C; Zhang, W; Zhang, X; Zhu, W, 2018)
"There are multiple regimens for the treatment of psoriasis including disease- modifying anti rheumatic drugs (DMARDS) and biologic agent, phototherapy and apremilast."( Chen, C; Gettas, T; Messiah, R; Metyas, S; Quismorio, A; Tomassian, C, 2019)
"To investigate the body location of treatment-resistant psoriasis in patients treated with biologic agents in real-world clinical practice, and to study the association between localization and quality of life."( Hjuler, KF; Iversen, L; Kofoed, K; Rasmussen, MK; Skov, L; Zachariae, C, 2019)
"Classically, the first line of treatment for nail psoriasis has been topical medication, but the new biological drugs seem to be the most effective treatment."( Hernández-Bel, P; Magdaleno-Tapial, J; Ortiz-Salvador, JM; Subiabre-Ferrer, D; Valenzuela-Oñate, C, 2018)
"Fumaric acid esters (FAEs) are used to treat psoriasis and are known to cause lymphopenia in roughly 60% of the patients."( Altmeyer, P; Bruckner, T; Dickel, B; Dickel, H; Höxtermann, S; Trinder, E, 2019)
"For the systemic treatment of nail psoriasis acitretin, methotrexate, cyclosporine, small molecules, and biologics may be employed."( Baran, R; Chiheb, S; Daniel, CR; Di Chiacchio, N; Gregoriou, S; Grover, C; Haneke, E; Iorizzo, M; Pasch, M; Piraccini, BM; Rich, P; Richert, B; Rigopoulos, D; Rompoti, N; Rubin, AI; Singal, A; Starace, M; Tosti, A; Triantafyllopoulou, I; Zaiac, M, 2019)
"Indeed, some treatments of psoriasis might be impaired by adiposity."( Chiricozzi, A; Girolomoni, G; Gisondi, P, 2019)
"Methotrexate (MTX) is an efficacious treatment for psoriasis; however, its widespread application is limited by its unpredictable efficacy."( Chang, YL; Fang, X; Han, L; Huang, Q; Jin, L; Li, XY; Qian, DF; Wu, MS; Xu, JH; Xu, QH; Yan, KX; Yawalkar, N; Zhang, Q; Zhang, XJ; Zhang, YJ; Zhang, ZH; Zheng, ZZ, 2019)
"Even as treatment of psoriasis becomes safer, it is important to recognize both common and uncommon adverse effects of treatment."( Cline, A; Feldman, SR; Kepley, AL; Kolli, SS, 2019)
"TGP can be used to treat psoriasis with reduced adverse reactions and recurrence rates."( Jiang, W; Li, B; Li, H; Li, X; Ma, T; Shen, F; Sun, X; Xie, S; Xu, W; Zheng, Q, 2019)
"Ustekinumab for the treatment of psoriasis is currently administered in a standard dosing regimen."( Busard, CI; Costanzo, A; De Keyser, E; Hutten, BA; Lambert, J; Lanssens, S; Meuleman, L; Spuls, PI; van den Reek, JM; Zweegers, J, 2019)
"Current treatment for psoriasis relies on conventional immunosuppressive agents."( Chen, H; Chen, Y; Dai, Z; Deng, J; Han, L; Huang, H; Liu, C; Liu, H; Lu, C; Wei, J; Xu, YY; Yan, Y, 2019)
"Following treatment of psoriasis, a decrease in aortic vascular uptake of 18F-FDG was associated with a reduction in AWT at 1 year."( Ahlman, MA; Aksentijevich, M; Al Najafi, M; Bluemke, DA; Choi, H; Dey, AK; Elnabawi, YA; Gelfand, JM; Genovese, LD; Goyal, A; Groenendyk, JW; Harrington, CL; Joshi, AA; Kabbany, MT; Mehta, NN; Natarajan, B; Playford, MP; Reddy, AS; Rodante, J; Sadek, A; Shukla, P, 2019)
"While many treatments for psoriasis exist, few are convenient and safe long term; even if sufficiently effective, treatments themselves often decrease quality of life and make long-term treatment adherence difficult."( Saruwatari, H, 2019)
"This study evaluated the treatment of psoriasis with esomeprazole."( Bafutto, M; Oliveira, EC; Zaterka, S, 2019)
"In summary, TXL may be able to treat psoriasis by regulating Th cells differentiation via inhibiting Notch1 and Jak2/Stat3 pathways."( Du, Z; Li, N; Lu, C; Wu, D; Yuan, X; Zhang, M; Zhu, W, 2020)
"Pioglitazone may be beneficial in the treatment of psoriasis."( Ding, Y; Guan, MM; Kang, XJ; Xiang, F; Yu, SR; Zhang, DZ; Zhang, JZ, 2020)
"Use of pioglitazone in the current treatment of psoriasis is beneficial."( Ding, Y; Guan, MM; Kang, XJ; Xiang, F; Yu, SR; Zhang, DZ; Zhang, JZ, 2020)
"Methotrexate (MTX) is the first-line treatment for psoriasis in China."( Chen, M; Chen, W; Chen, X; Kuang, Y; Liu, P; Lu, Y; Lv, C; Qin, Q; Yan, K; Zhang, M; Zhu, W, 2020)
"It was also investigated for the treatment of plaque psoriasis, although it is not approved by the Food and Drug Administration for this indication."( Georgakopoulos, JR; Ighani, A; Yeung, J, 2020)
"The Oral-treatment Psoriasis Trial (OPT) study series demonstrated that tofacitinib is efficacious in the treatment of plaque psoriasis with an acceptable safety profile."( Georgakopoulos, JR; Ighani, A; Yeung, J, 2020)
"Therapies to treat psoriasis include phototherapy, non‑steroidal and steroidal drugs, as well as antibodies to block tumor necrosis factor‑α, interleukin (IL)‑17‑A and IL‑12/IL‑23, which all focus on decreasing the proinflammatory hallmark of psoriasis."( Briseño-Lugo, PE; Cancino-Diaz, JC; Cancino-Diaz, ME; Díaz-Toalá, I; Gómez-Chávez, F; Gutiérrez-Gonzalez, G; Mendoza-Figueroa, JS; Pérez-Tapia, SM; Rodríguez-Martínez, S; Torales-Cardeña, A; Vázquez-Sánchez, EA; Zapi-Colín, LA, 2020)
"Effective treatment of scalp psoriasis is essential for improving the quality of life of psoriasis patients."( Alsenaid, A; Ezmerli, M; Heppt, M; Illigens, BM; Prinz, JC; Srour, J, 2022)
"The estimated cost to treat psoriasis in USA is over 13 billion US dollars per year."( Awasthi, R; Jindal, S; Kulkarni, GT; Singhare, D, 2020)
"Cal/BD formulations are efficacious treatment for psoriasis."( Camela, E; Cinelli, E; Fabbrocini, G; Megna, M, 2020)
"The major problem in the topical treatment of psoriasis is drug localization through the psoriasis lesions."( Anbardar, MH; Chavoshy, F; Tamaddon, AM; Zadeh, BSM, 2020)
"The optimized batch was used for the treatment of psoriasis lesions in the mice model."( Anbardar, MH; Chavoshy, F; Tamaddon, AM; Zadeh, BSM, 2020)
"In these studies, treatment of scalp psoriasis with Cal/BD foam provided good efficacy for adults and adolescents and was generally well tolerated."( Lebwohl, M; Petersen, B, 2020)
"UVB phototherapy is treatment for psoriasis, which increases phospholipid oxidative modifications in the cell membrane of the skin."( Dobrzyńska, I; Domingues, MR; Domingues, P; Skrzydlewska, E; Wroński, A; Łuczaj, W, 2020)
"Despite successful treatment of psoriasis by blocking IL-23, the regulation of IL-23 expression in psoriasis patients is largely unknown."( De La Torre, R; Ehst, B; Greiling, T; Leitenberger, J; Liu, Y; McClanahan, D; Ortega-Loayza, AG; Sawka, E; Simpson, E; Strunck, J; Wang, Z, 2021)
"Regarding the choice of treatment for psoriasis in men with a paternity project, methotrexate should be avoided in the 3 months prior to conception even though the data on many pregnancies occurring on methotrexate are reassuring."( Brenaut, É, 2020)
"Clinical treatment in psoriasis with secukinumab restored the suppressive function and increased production of TGF-β in Tregs of psoriasis."( Bai, X; Dang, E; Li, B; Liu, Y; Wang, G; Wang, L; Xiao, C; Yang, L; Yu, C; Zhang, C, 2021)
"To study the new insights in the treatment of psoriasis and future prospects."( Easwari, TS; Singh, A, 2021)
"A drug used in the treatment of psoriasis of moderate and acute strength is the monoclonal antibody anti-TNF-adalimumab."( Adwent, I; Brus, R; Grabarek, BO; Kasela, T; Zawidlak-Węgrzyńska, B, 2021)
"Thus, scopolamine has potential for the treatment of psoriasis."( Cai, Q; Li, G; Li, M; Li, Q; Song, N; Yu, B; Zhi, Y, 2021)
"Response to treatments in psoriasis can be assessed using the PASI response 50, 75, 90 or 100."( Belinchón Romero, I; Carrascosa Carrillo, JM; Dauden, E; Ferrándiz Foraster, C; González-Cantero, Á, 2022)
"However, products for the topical treatment of mild psoriasis are still required."( Gendrisch, F; Haarhaus, B; Krieger, N; Quirin, KW; Schempp, CM; Wölfle, U, 2021)
"Wide treatment options used to treat psoriasis is associated with various adverse effects."( Devabattula, G; Gangadevi, V; Godugu, C; Pooladanda, V; Thatikonda, S, 2021)
"CAL/BDP cream is a novel topical treatment of psoriasis, which in a single product, offers a unique combination of high efficacy combined with favorable safety and excellent treatment convenience."( Dhawan, S; Green, LJ; Praestegaard, M; Selmer, J; Stein Gold, L; Vestbjerg, B, 2021)
"Among the different treatments for psoriasis, statins have been found to reduce the severity of the disease."( Al Salman, M; Azizpour, A; Farid, AS; Ghiasi, M; Mahmoudi, H; Taraz, M, 2021)
"Topical treatments of psoriasis are either associated with limited response or with side effects."( Chan, TC; Chang, WY; Huang, WC; Krueger, JG; Lee, MS; Tsai, TF, 2021)
"More than 90% of patients previously treated for psoriasis evaluated the Cal/BD foam more effective, easier to use and better tolerated compared to previous topical treatments at PPQ."( Argenziano, G; Atzori, L; Bianchi, L; Campanati, A; Corazza, M; Damiani, G; De Pità, O; Donini, M; Fargnoli, MC; Feliciani, C; Mazzatenta, C; Mazzotta, A; Offidani, A; Peris, K; Potenza, C; Prignano, F; Stingeni, L; Tiberio, R, 2021)
"This study evaluated whether FJDH treated psoriasis and its specific mechanism for the efficacy in mice."( Kong, L; Li, M; Lv, W; Meng, S; Qiao, H; Song, C; Sun, Y; Wang, X; Yang, C; Zhu, Y, 2021)
"UVB phototherapy is commonly used to treat psoriasis, although this has undesirable side effects, and is often combined with anti-inflammatory compounds."( Gęgotek, A; Skrzydlewska, E; Wójcik, P; Žarković, N, 2021)
"have a better clinical efficacy in the treatment of psoriasis, there is a lack of overall understanding of the mechanism of their treatment, especially about some immune cells and proteins closely related to psoriasis and their relationship in executive function and biological significance."( Cheng, G; Kuang, H; Su, Y; Wang, Q; Wu, L; Zhang, F, 2022)
"Apremilast is approved for the treatment of psoriasis and psoriatic arthritis."( de la Brassinne, M; Ghislain, PD; Hillary, T; Lam Hoai, XL; Lambert, J; Roquet-Gravy, PP; Segaert, S, 2022)
"CAL/BDP PAD-cream is a novel topical treatment for psoriasis, which through PAD™ Technology offers substantial improvement in QoL and treatment satisfaction for patients."( Armstrong, A; Koo, J; Pinter, A; Præstegaard, M; Reich, A; Selmer, J, 2022)
"In literature, adalimumab treating pustular psoriasis in pediatric has been described in six children who failed in prior treatment."( Chen, M; Dong, Z; Du, Y; Wang, F; Yan, Q, 2022)
"As a TCM and effective medicine for the treatment of psoriasis, Indigo Naturalis (Baphicacanthus Cusia (Nees) Bremek."( Du, A; Han, L; Li, G; Lin, J; Wang, F; Xie, J; Yang, M; Zhang, D; Zhang, Q, 2022)
"Despite there being advanced treatment options, psoriasis remains an incurable and recurring disease."( Fatima, G; Husain, N; Jabeen, A; Kazmi, MH; Uddin, Q, 2023)
"Despite advances in the treatment of psoriasis, namely among biologic agents, an oral, effective and safe new drug can bring several advantages to prescribers and patients."( Lé, AM; Puig, L; Torres, T, 2022)
"Clinical treatment of psoriasis remains challenging because of possible long-term drug toxicities and loss of therapeutic effects over time."( Dai, C; Guo, X; Jiang, F; Wang, J; Wu, X; Yin, Q, 2023)
"The systemic treatment of psoriasis has changed markedly with the introduction of many novel drugs."( Imafuku, S; Sato, E; Takano-Kawasaki, S; Yamaguchi, K, 2023)
"Safe and effective treatments for psoriasis that also address itch are needed."( Alonso-Llamazares, J; Berk, DR; Draelos, ZD; Feng, A; Gooderham, MJ; Higham, RC; Kempers, SE; Kircik, LH; Lebwohl, MG; Papp, KA; Pariser, DM; Stein Gold, L; Toth, DP; Yosipovitch, G, 2023)
"Topical therapies are commonly used to treat psoriasis, either as monotherapy for milder disease or as adjuncts to systemic and biologic drugs."( Bhatia, N; Jacobson, A; Kircik, L; Lain, E, 2023)
"Topical vitamin D analogues are routine treatment for psoriasis, but the effect of oral supplementation has not been established."( Danielsen, K; Furberg, AS; Jenssen, M; Jorde, R; Wilsgaard, T, 2023)
"A major drawback of using MTX to treat psoriasis is its limited diffusion through the skin, which may cause insufficient penetration of MTX into the basal layer of the epidermis, where psoriatic cells are generated."( Al-Nemrawi, NK; Alzoubi, KH; Khafajah, AS, 2023)
"CAL/BDP PAD-cream is a novel topical treatment of psoriasis that has a high efficacy and a favourable safety profile combined with a superior patient-reported treatment convenience."( Arenberger, P; Armstrong, A; Augustin, M; Gold, LS; Iversen, L; Pinter, A; Praestegaard, M; Reich, A, 2023)

Research

Studies (14,416)

TimeframeStudies, This Condition (%)All Conditions %
pre-19905968 (41.40)23.3326
1990's1905 (13.21)12.5806
2000's1834 (12.72)18.1394
2010's3067 (21.27)28.8240
2020's1642 (11.39)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low240
2,3-diphosphoglycerate0low10
3-hydroxykynurenine0low10
gamma-aminobutyric acid0low80
aminolevulinic acid0medium378
5-hydroxytryptophan0low10
acetic acid0low20
acetaldehyde0low10
acetamide0low10
acetone0low40
adenine0low140
allantoin0medium124
ammonium hydroxide0low70
anthranilic acid0low10
quinacrine0low60
benzene0low20
benzoic acid0medium31
betaine0low10
bromide0medium71
butyric acid0medium21
carbamates0low70
carbon monoxide0low20
carnitine0low30
catechol0low10
choline0low40
citric acid, anhydrous0low10
chlorine0medium121
hydrochloric acid0low20
coumarin0low10
gallic acid0low60
hydrogen sulfide0low60
3-hydroxybutyric acid0low10
bupropion0low110
guaiacol0low10
methylmalonic acid0low10
n(g),n(g')-dimethyl-l-arginine0low30
phosphonoacetic acid0low20
3,4-dihydroxyphenylacetic acid0low10
aminocaproic acid0medium21
creatine0low30
cytosine0low20
lactic acid0medium162
dihydroxyacetone0low10
dimethyl sulfoxide0medium143
ethanolamine0low10
formaldehyde0medium71
formamide0low10
glycine0low210
glycerol0medium71
glycolic acid0medium22
hydrogen carbonate0low10
dalteparin0low10
histamine0medium664
hydrogen0low30
imidazole0low20
iodine0low280
itaconic acid0low10
dihydroxyphenylalanine0low130
kynurenine0low60
thioctic acid0medium21
pyruvaldehyde0low40
methanol0low30
inositol0medium122
melatonin0low60
croton oil0medium81
naphthalene0low20
nickel0medium251
niacin0low190
nitrates0medium52
nitrites0medium72
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du-212200low10
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5-methylangelicin0low30
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n-methyladenosine0low20
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hydrogen sulfite0low20
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arginyl-glycyl-aspartic acid0low20
vitamin b 60low30
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s-nitrosoglutathione0low10
p-tert-butylphenolformaldehyde resin0low10
cp 963450low10
artesunic acid0low10
pyridinoline0low10
deoxypyridinoline0low10
epibatidine0low10
4-hydroxydebrisoquin0low10
aminomethyltrioxsalen0low10
7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one0low10
sivelestat0low10
22-hydroxycholesterol0low10
4,4',6-trimethylangelicin0low40
perindopril0low10
ethacizine0low40
procyanidin0low40
2'-5'-oligoadenylate trimer0low10
solenopsin a0low10
fingolimod hydrochloride0low50
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asiaticoside0low10
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deoxyglucose0low10
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thromboxanes0medium31
1-(carboxymethylthio)tetradecane0medium32
zinc coproporphyrin iii0low10
sc 419300low10
fe(ii)-edta0low10
8-azidoadenosine-3',5'-monophosphate0medium61
prunasin0low10
sr 486920low10
astilbin0low70
ginsenoside rh20low10
rhein-9-anthrone0low10
gr 736320low10
carboxypolymethylene0low20
sm 12130low10
phytosphingosine0low20
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l 6513920low10
sulfadiazine, tetroxoprim drug combination0low10
6-hydroxy-5-methoxy-2-indolylcarboxylic acid0low10
emodin anthrone0low10
astragaloside a0low10
celastrol0low60
aloe emodin anthrone0low10
imatinib mesylate0low100
tazobactam0low10
gefitinib0low20
n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine0medium32
n(6)-carboxymethyllysine0low10
technetium tc 99m hydroxymethylene diphosphonate0low20
n,n-dimethylarginine0low30
f-chemotactic peptide0low10
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone0low10
3-hydroxymethylantipyrine0low10
glabridin0low10
tetrahydrocurcumin0low10
rubimaillin0low10
iguratimod0low10
glycerophosphoinositol 4,5-bisphosphate0low10
n-methylisoindigotin0low10
9-fluoroprednisolone0low10
delphinidin0low40
cyanidin0low10
snp nonapeptide0low10
ym 5290low10
dexpanthenol0low10
safinamide0low10
l 7330600low10
omega-n-methylarginine0medium11
15-hydroxyeicosatrienoic acid0low10
butoxamine0low10
cycloastragenol0low10
xylose0low60
beta-lactams0low10
phytol0low10
proline0low100
betamethasone dipropionate, salicylic acid drug combination0medium32
betamethasone-17,21-dipropionate0medium246123
docetaxel anhydrous0low50
cilomilast0low20
vx 4970low10
8-methoxymethyl-3-isobutyl-1-methylxanthine0low10
naproxen0medium83
hydroxyl radical0low30
methyl 5-aminolevulinate0low20
atazanavir sulfate0low10
olmesartan0low20
atrasentan0low10
resiquimod0low20
4,8-dimethyl-5'-carboxypsoralen0low10
singlet oxygen0low20
cryptotanshinone0low20
cyc 2020low10
ar-turmerone0low10
neodymium pyrocatechin disulfonate0low10
dhurrin0low10
ampelopsin0low10
psoberan0medium31
methylinositol0low10
4-oxopentanal0low10
clorazepate dipotassium0low10
oxoline0low10
varenicline0low10
biotin0low60
o-4-nitrophenyl phenylphosphonate0low10
angiotensin ii0medium31
1-nitrohydroxyphenyl-n-benzoylalanine0low20
atropine0medium61
sb 2035800low10
erlotinib hydrochloride0low50
organophosphonates0low50
ly 2931110medium22
sch 401200low10
deflazacort0low10
7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-propanoic acid0low10
fe(iii)-edta0low10
troleandomycin0low10
lapatinib0low10
dabigatran0low20
sorafenib0low90
lenalidomide0low20
demecolcine0low10
deoxycholic acid0low10
cortisone0low520
5-hydroxymethylfurfural0medium11
nsc 748590low10
anisomycin0low40
benzofurans0medium101
khellactone0low10
noscapine0low10
acivicin0low10
withanolides0low50
acronine0low10
erianin0low10
trimethoprim, sulfamethoxazole drug combination0low110
5-demethylnobiletin0low20
sta-210medium11
bortezomib0low50
ritonavir0low20
dihydropyridines0low10
1-methoxy-10H-acridin-9-one0low10
carboplatin0low20
lithium chloride0low20
glycogen0low300
n-acetylneuraminic acid0low20
fibrin0low150
bradykinin0medium71
glucosamine0low90
elastin0low50
naringenin0low20
epiglucan0low20
3,4-dihydroxyphenyllactic acid0low10
inositol 1,4,5-trisphosphate0low10
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puromycin0low20
taxifolin0low20
tartaric acid0low10
n-formylmethionine0low20
inositol 3-phosphate0low90
quinidine0low20
griseofulvin0low170
cefoxitin0low10
saquinavir0low10
bacampicillin0low10
indican0low10
convallatoxin0low10
ginsenoside rg10low20
cimifugin0low10
carnosol0low10
naringin0low10
ochratoxin a0low10
Rhododendrin0low10
cyclopamine0low50
lignans0low30
n-formylmethionine leucyl-phenylalanine0low120
actinonin0low10
halcinonide0medium119
amcinonide0medium44
flumethasone pivalate0low20
betadex0low30
tretinoin0medium26059
arachidonic acid0medium563
3-hydroxy-3-methylglutaryl-coenzyme a0low10
resveratrol0medium81
retinol0medium19026
oleic acid0medium131
ferulic acid0low10
pectins0medium11
cocaine0low20
eicosapentaenoic acid0medium307
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mycophenolic acid0medium529
mupirocin0low30
clindamycin0low30
lycopene0low10
zithromax0low50
y 276320low10
prostaglandin d20low50
diethylstilbestrol0low40
afimoxifene0low20
decitabine0low10
iridoids0low10
valrubicin0low10
cefamandole0medium11
dactinomycin0low40
gamma-sitosterol0low20
melphalan0low40
enkephalin, leucine0medium52
tenofovir0low30
l 743,8720low10
shikonin0low40
bx 4710low10
sodium bicarbonate0low20
zn(ii)-phthalocyanine0low20
dipyrone0low10
bromochloroacetic acid0medium32926
calix(4)arene0low10
naphthalan0medium21
sch 222190medium22
carbenoxolone sodium0low10
cinnamaldehyde0low10
geraniol0low10
glycosides0medium81
isomethyleugenol0low60
piplartine0low10
retinaldehyde0low10
piperine0low10
squalene0low10
stilbenes0medium3010
diethyl fumarate0low30
isoliquiritigenin0low10
xanthohumol0low10
picibanil0low30
p-hydroxycinnamaldehyde0low10
citraconic acid0low120
cannabidiol0medium81
buprenorphine0low10
pyrophosphate0low100
gw96620low10
s 10330low10
dihydrosphingosine 1-phosphate0low20
bz-4230low10
amygdalin0low60
polidocanol0low30
tiamulin0low10
leuprolide0low10
fludarabine0low50
propylthiouracil0medium186
sesquiterpenes0low70
mercaptopurine0low240
ag-2130low10
captax0low10
urocanic acid0low70
curcumin0medium496
thiohydantoins0low10
methimazole0medium72
capsaicin0medium196
levocetirizine0low20
terbinafine0low240
n-(4-(n-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide0low10
oxazolone0low80
thioguanine anhydrous0medium142
thiobarbituric acid0low10
thiourea0low10
indigo carmine0medium113
D-fructopyranose0low30
unithiol0medium31
brij-580low10
5-doxylstearate0medium21
digoxin0low20
meso-1,2-diphenylethylenediamine, (r-(r*,s*))-isomer0medium11
tamoxifen0low70
nadp0low240
1,1-diphenyl-2-picrylhydrazyl0low10
stattic0low10
krn 70000low10
methyl-thiohydantoin-tryptophan0low10
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene0low10
fusidic acid0medium134
lincomycin0low10
thiopental0low10
ranitidine0medium126
u 01260low10
n-bromotaurine0low10
lithium0low660
cobaltous chloride0low20
mercuric chloride, ammoniated0low10
dermatan sulfate0low40
hydroxylysine0low10
mannomustine0low10
quinine0low40
2,2-dimethyl-5-hydroxy-1-pyrrolidinyloxy0low10
rtki cpd0low10
l 6523430low10
cystine0low30
galactaric acid0low10
vx-7450low10
freedom0low20
safingol0low20
oxalylglycine0low10
peptide t amide0medium21
calixarenes0low10
ay 236260low10
cytellin0low30
thymic factor, circulating0low10
ginsenosides0low50
3-mercapto-1-propanesulfonate0low20
ovalbumin0low40
sodium dodecyl sulfate0low100
l 6635360medium21
zinc protoporphyrin ix0low20
sb 2250020low10
alpha-chymotrypsin0low30
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione0medium11
17-ketosteroids0low190
naphthoquinones0low100
sc 5600low10
digitoxigenin0low10
osteoprotegerin0low60
cathepsin g0medium71
icodextrin0low20
jnj 77771200low20
ex 5270low10
tetrathiomolybdate0low10
eupatilin0low10
sphingosine0low120
quercetin0low70
bilirubin0low120
dinoprostone0medium241
dinoprost0low30
leukotriene a40low20
apigenin0low30
luteolin0low60
linoleic acid0medium102
vitamin k semiquinone radical0low30
beta carotene0medium63
leukotriene b40medium10611
leukotriene c40low10
thromboxane a20low40
daphnetin0low10
8,11,14-eicosatrienoic acid0low50
luteolin-7-glucoside0low10
rosin0low20
alprostadil0low30
5-hydroxy-6,8,11,14-eicosatetraenoic acid0low70
stigmasterol0low10
rutin0low50
kaempferol0low10
20-carboxyleukotriene b40low10
leukotriene e40low30
6-ketoprostaglandin f1 alpha0low30
lipoxin a40low20
gamma-linolenic acid0medium52
alpha-linolenic acid0low30
prostaglandin f10low10
genistein0medium61
amphotericin b0medium82
pulmicort0medium1810
kava0low10
previtamin d(3)0low10
paricalcitol0medium11
canthaxanthin0medium11
fucoxanthin0low10
mezerein0low10
esculetin0low10
humulene0low20
oleuropein0low10
amentoflavone0low10
chrysin0low10
diosmin0low10
fisetin0low10
galangin0low10
hispidulin0low10
mangiferin0low10
epsilon-viniferin0low10
rosmarinic acid0low20
psoralidin0low10
tectorigenin0low10
rottlerin0low20
coenzyme q100medium44
l 6835900low20
26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin d30medium21
tranilast0low10
isotretinoin0medium637
olopatadine hydrochloride0low10
pitavastatin0low10
clocortolone pivalate0medium31
hydrocortisone valerate0medium43
9-hydroxy-10,12-octadecadienoic acid0low20
13-hydroxy-9,11-octadecadienoic acid0low50
leukotriene b50low20
thromboxane b20medium83
thromboxane b30medium11
5-oxo-6,8,11,14-eicosatetraenoic acid0low10
arachidonic acid 5-hydroperoxide0low20
4-hydroxy-2-nonenal0low40
1-monooleoyl-rac-glycerol0low10
ubiquinone 80medium11
menaquinone 60medium11
sphingosine 1-phosphate0low100
codeine0low20
phenylephrine hydrochloride0medium71
dihydrocodeine0low10
hydroxystilbamidine0low10
oxycodone0low10
sirolimus0medium183
topiramate0low10
menaquinone 70medium11
fenretinide0low10
kh 10600medium11
morphine0low10
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid0medium21
4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide0low10
clobetasol0medium297138
desonide0medium53
fluticasone0medium108
kallidin0low10
goserelin0low10
halobetasol0medium5733
iloprost0low10
lysophosphatidic acid0low50
lysophosphatidylcholines0low40
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester0low10
cytochalasin b0low20
pholcodine0low10
andrographolide0low10
koumine0low10
casein kinase ii0low20
ag-4900low10
su 112480low60
palbociclib0low10
nifuroxazide0low10
mitoguazone0medium52
lead0low40
12-hydroxy-5,8,10,14-eicosatetraenoic acid0medium402
15-hydroxy-5,8,11,13-eicosatetraenoic acid0medium161
bay 11-70820low30
8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid0low10
10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid0low20
pd 1517460low10
antimony0low20
cesium0low10
barium0low10
ethyl fumarate0medium154
aluminum0low40
strontium0medium21
bismuth0low40
thallium0low10
arsenic0medium821
lisinopril0low20
indinavir sulfate0low10
sulfur0low280
costunolide0low10
monomethyl fumarate0low20
rd6 50710low10
diphenylhexatriene0low10
7-hydroxymethotrexate0medium31
dichlorisone acetate0low10
enalapril0low40
nitrofurazone0low30
sinomenine0low10
deoxyribose0low20
fumarates0medium20927
beryllium0low20
cysteine0low70
thyronines0low10
silicon0low10
phosphorus0medium201
boron0low10
heroin0low10
trandolaprilat0low10
bakuchiol0low40
pepstatin0low10
ancriviroc0medium11
pregabalin0low30
oxyfedrine0low10
aliskiren0low10
triolein0low20
resiniferatoxin0low10
25-hydroxyvitamin d 20medium11
salubrinal0low10
cefotaxime0medium11
8,11,12-trihydroxy-5,9,14-eicosatrienoic acid0low10
proguanil0low20
motretinide0low10
selenium0medium356
tellurium0low10
radium0low10
(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid0low10
maxacalcitol0medium258
dizocilpine maleate0low10
antimycin a0low10
simethicone0medium21
24,25-dihydroxyvitamin d 30medium21
tiacrilast0medium11
cilastatin0low10
1-palmitoyl-2-oleoylphosphatidylcholine0low10
vitamin a20low20
temarotene0low10
sdz imm 1250medium11
ro 13-62980medium61
involucrin0medium503
1,2-dioleoyloxy-3-(trimethylammonium)propane0low30
dioleoyl phosphatidylethanolamine0low10
l 6518960low10
ro 24-02380medium11
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid0low10
st 2320low10
echinacin0low10
everolimus0low10
prostaglandin f-main urinary metabolite0low30
12-hydroxy-5,8,10,14,17-eicospentaenoic acid0low10
elaiophylin0low10
axitinib0low10
i(3)so3-galactosylceramide0low20
technetium tc 99m pyrophosphate0low50
verlukast0low10
beta-escin0low50
nitrofurantoin0low30
sq-233770low30
tipredane0medium22
pki 1660low10
awd 12-2810low10
voclosporin0medium105
lu 2080750low10
epsilon-(gamma-glutamyl)-lysine0low10
staurosporine0low20
tei 96470low10
hypericum0medium21
phosphocreatine0low30
chlorhexidine0low20
thioacetazone0low20
s 17430low10
gs-73400low10
amoxicillin-potassium clavulanate combination0low30
acth (4-7), pro-gly-pro-0low10
lu 28-1790low10
sincalide0low20
capryloyl salicylic acid0medium11
technetium tc 99m diphosphonate0low10
etomoxir0low10
halometasone0medium74
ginsenoside m10low20
gambogic acid0low10
sb 2422350low10
mocetinostat0medium411
alloin0low10
scio-4690low10
ticagrelor0low10
mart-1 antigen0low10
ginsenoside rb10low10
psd 5020low20
sorbitan monooleate0low20
ammonium trichloro(dioxoethylene-o,o'-)tellurate0low10
6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-n-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6s)-0low10
linagliptin0low10
apilimod0medium11
apixaban0low10
2-methylnaphtho(2,3-b)furan-4,9-dione0low10
artenimol0low20
betrixaban0low10
2-acetylfuranonaphthoquinone0low20
vx 7020low10
hydrocortisone 21-butyrate0low10
aurotioprol0medium22
5s,12r,18r-trihydroxy-6z,8e,10e,14z,16e-eicosapentaenoic acid0low10
oxadiazoles0low10
5,15-diphenylporphine0low10
ribose0low30
regorafenib0low10
acetyl-11-ketoboswellic acid0low30
px 4780low10
zm 2528680low10
nystatin a10medium81
ponesimod0medium62
apratastat0low10
oleandrin0low10
6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-n-(2,2-dimethylprpyl)-3-pyridinecarboxamide0low10
sitagliptin phosphate0medium42
idelalisib0low10
methyl 4-(adenin-9-yl)-2-hydroxybutanoate0low20
trametinib0low20
losartan potassium0medium21
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc0medium92
n-acetylmannosamine0medium11
empagliflozin0low10
technetium tc 99m exametazime0low10
diflucortolone0medium53
calcimycin0low80
dextrothyroxine0low60
sepharose0low40
indocyanine green0low20
scopolamine hydrobromide0low20
dactolisib0low10
pituitrin0low20
podophyllin0medium101
virginiamycin0low20
rhodomyrtone0low20
phytosterols0low20
dihydrotachysterol0low20
clove0low10
acid phosphatase0low460
mefloquine0low10
cp 806330low10
cysteinyldopa0medium81
curcumol0low10
jaw0low20
ly 2539630low10
nad0medium181
protectin d10low10
cytochrome c-t0low40
bms-6500320low10
9-fluorocortisone0low10
cosyntropin0medium72
cholecystokinin0low30
dynorphins0low10
atrial natriuretic factor0low20
adrenocorticotropin zinc0low10
hes1 protein, human0low40
vitisin a0low10
humanin0low20
fibrinopeptide b0low10
gastrins0low10
glucagon0low70
beta-endorphin0low70
thymopoietin iii0low10
neuropeptide y0low20
peptide phi0low10
angiotensinogen0low20
cortistatin 140low10
tannins0medium11
oligonucleotides0medium101
liraglutide0medium182
glucagon-like peptide 10low110
insulin detemir0low10
incretins0low50
c-peptide0low70
ristocetin0low10
cellulose0low40
endothelin-10medium121
phosphatidylcholines0medium141
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one0medium21
pamapimod0low10
gdc-09730low20
chlorophyll a0low10
sodium salicylate0low10
sphingosine kinase0low20
ubiquinone0medium74
cilastatin, imipenem drug combination0low10
benzoylaconine0low10
calpain0low40
sapogenins0low10
silicate cement0low10
chitosan0low110
ph 7978040low10
pha 4080low10
technetium tc 99m sestamibi0low10
15-deoxyprostaglandin j20low10
serlopitant0medium11
bucladesine0medium81
stearates0low10
ro13-99040low20
sodium pertechnetate tc 99m0low40
sodium ethylxanthate0low40
chiniofon0low10
thiostrepton0low10
lde2250low10
gdc 04490low10
preminent0low10
valbenazine0low10
pci 327650low20
madecassoside0low30
intrinsic factor0low10
oxymatrine0medium52
apalutamide0low10
quetiapine fumarate0low20
cardiovascular agents0low70
neurotensin0low20
fibrinopeptide a0low20
mannans0low80
bms-7900520low50
cx 54610low10
peptones0low10
plx40320low10
a 9670790low10
urushiol0low20
glycolipids0medium81
elafin0low80
piperidines0medium12535
resolvin d10low20
thymosin0low20
5-hydroxymethyl-2'-deoxyuridine0low20
interleukin-80medium18411
dabrafenib0low30
punicalagin0low10
gardiquimod0low10
oclacitinib0low10
sofosbuvir0low70
exenatide0low60
gsk06600low10
arry-3717970low10
calcipotriene0medium647258
glpg06340medium61
methylcellulose0low80
eliglustat tartrate0low10
1,2-dioleoyl-sn-glycero-3-phosphoglycerol0low10
vasoactive intestinal peptide0medium161
natriuretic peptide, brain0low40
heme0low20
leukotoxin0low10
chondroitin0low80
heparitin sulfate0medium101
ascorbic acid0low330
novobiocin0medium11
tetracycline0low230
chlortetracycline0low10
oxytetracycline, anhydrous0low60
minocycline0low80
methacycline0low10
salicylates0medium13526
dicumarol0low30
piroxicam0medium72
isoxicam0low20
demeclocycline0low30
citrinin0low10
teriflunomide0low30
ethyl biscoumacetate0low10
lornoxicam0low10
s 1 (combination)0low10
epidermal growth factor0medium615
gastrin-releasing peptide0low10
calca protein, human0low10
transforming growth factor beta0medium591
semaglutide0low10
phosphatidylethanol0low10
sr90090low10
brine0medium22
cefuroxime axetil0low10
chf60010low10
plecanatide0low10
thymic factor, circulating0low20
rome0low40
sklb10020low10
agar0low50
glutaminase0low10
cyclin d10medium101
sorbitan monolaurate0low10
caseins0low20
tetraphenylporphine0low10
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone0low10
nitrophenols0low20
prn6940low20
lewis x antigen0low60
1 alpha,24-dihydroxyvitamin d30medium6525
calpastatin0low10
cobamamide0low10
hyaluronoglucosaminidase0low100
epoetin alfa0low10
lipofectamine0low10
ginkgolide b0low10
peoniflorin0low70
vitamin b 120medium502
betamethasone 21-valerate0medium11
glucosaminylmuramyl-2-alanine-d-isoglutamine0medium21
insulin glargine0low20
ecallantide0low10
oxyntomodulin0low10
transforming growth factor alpha0medium311
cyclosporine0medium719109
silybin0low10
peptide yy0low10
lactoferrin0medium62
peptide t0medium173
catalpol0low10
phenylbutazone, propyphenazone drug combination0low10
orabase0low10
technetium tc 99m medronate0low100
apyrase0medium21
muramidase0low170
khasianine0low10
chondroitin sulfates0medium112
promega0medium53
exudates0low290
angiogenin0low10
entecavir0low20
acyclovir0medium101
levoleucovorin0medium181
cyclic gmp0low440
deoxyguanosine0medium61
dihydrofolate0low10
guanosine triphosphate0low10
guanine0medium61
guanosine0low10
hypoxanthine0low10
inosine0low10
folic acid0medium1067
neopterin0medium91
rifampin0medium203
clozapine0low10
dacarbazine0low10
ganciclovir0low10
olanzapine0low20
allopurinol0medium153
5,10,15,20-tetrakis(4-methoxyphenyl)porphyrin0low10
8-hydroxyguanosine0low10
5,11-methenyltetrahydrohomofolate0low10
peldesine0low10
5-(4-aminophenyl)-10,15,20-triphenylporphyrin0low10
nintedanib0low20
8-hydroxy-2'-deoxyguanosine0medium61
prodigiosin0low40
5-methyltetrahydrofolate0low20
cytidylyl-3'-5'-guanosine0low10
insulin0low10
ag 850low10
alcian blue0low40
cholestyramine resin0low40
s 34830low10
eye0low170
carbidopa0low10
ego0low10
concanavalin a0medium281
metallothionein0low10
dactinomycin0low10
phosphorus radioisotopes0low60
preproenkephalin0low10
leptin0medium552
pyrimidinones0low30
phenanthrenes0medium51

Protein Targets (4,409)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Cytochrome P450 2C9 01096121
IDH112900129
chromobox protein homolog 123200232
geminin38500385
Chain A, HADH2 protein12600126
Chain B, HADH2 protein12600126
Chain A, Ferritin light chain10900109
Chain A, Cruzipain800080
thioredoxin reductase20600206
USP1 protein, partial20600206
GLS protein15300153
TDP1 protein43700437
Microtubule-associated protein tau20600207
regulator of G-protein signaling 413700137
glucocorticoid receptor [Homo sapiens]34000340
peroxisome proliferator-activated receptor delta19900199
peroxisome proliferator activated receptor gamma24100241
vitamin D (1,25- dihydroxyvitamin D3) receptor20100201
arylsulfatase A10500105
Bloom syndrome protein isoform 112400124
cellular tumor antigen p53 isoform a960096
cytochrome P450 2C9 precursor860086
vitamin D3 receptor isoform VDRA16600166
thyroid hormone receptor beta isoform a11600116
DNA polymerase beta580058
nuclear factor erythroid 2-related factor 2 isoform 130600306
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1700070
M-phase phosphoprotein 8680068
histone acetyltransferase KAT2A isoform 114000140
muscarinic acetylcholine receptor M1900090
Polyunsaturated fatty acid lipoxygenase ALOX15B827089
Alpha-synuclein4918168
Histamine H2 receptor13383151
Peroxisome proliferator-activated receptor alpha971027
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A930093
Chain A, RNA-directed RNA polymerase NS50404
acid sphingomyelinase240024
importin subunit beta-1 isoform 1560056
flap endonuclease 110200102
serine/threonine-protein kinase PLK1380038
snurportin-1560056
GTP-binding nuclear protein Ran isoform 1320032
DNA polymerase eta isoform 1510051
DNA polymerase iota isoform a (long)15400154
urokinase-type plasminogen activator precursor970097
plasminogen precursor970097
urokinase plasminogen activator surface receptor precursor970097
DNA polymerase kappa isoform 112500125
fibroblast growth factor 22 isoform 1 precursor0002
Mitogen-activated protein kinase 13091322
Beta-lactamase012012
Transthyretin0161434
Fatty acid-binding protein, intestinal08210
Fatty acid-binding protein, adipocyte08412
Cyclin-A2012113
Cannabinoid receptor 1010212
Cyclin-dependent kinase 20273866
Choline O-acetyltransferase0303
Mitogen-activated protein kinase 12091625
Guanine nucleotide-binding protein G460046
Fatty acid-binding protein 50527
Fatty acid-binding protein 50022
Mitogen-activated protein kinase 110123547
Mitogen-activated protein kinase 140423779
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE20800208
Platelet-activating factor receptor46011
Inositol monophosphatase 1700070
Luciferase16200162
RAR-related orphan receptor gamma30500305
GLI family zinc finger 332200322
AR protein43100431
nuclear receptor subfamily 1, group I, member 325800258
progesterone receptor21600216
retinoic acid nuclear receptor alpha variant 131700317
retinoid X nuclear receptor alpha27300273
farnesoid X nuclear receptor20000200
pregnane X nuclear receptor29800298
estrogen nuclear receptor alpha49200492
aryl hydrocarbon receptor16600166
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a23800238
activating transcription factor 614000140
v-jun sarcoma virus 17 oncogene homolog (avian)16100161
Histone H2A.x15600156
thyroid hormone receptor beta isoform 231400314
heat shock protein beta-112100121
Cellular tumor antigen p5328300283
nonstructural protein 1660066
glucocerebrosidase630063
P53150015
nuclear receptor ROR-gamma isoform 117600176
Broad substrate specificity ATP-binding cassette transporter ABCG2048455
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, Phosphodiesterase 9A0101
Chain A, Class I phosphodiesterase PDEB10101
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
glp-1 receptor, partial11300113
thyroid stimulating hormone receptor16300163
estrogen-related nuclear receptor alpha37400374
Phosphodiesterase 0505
mitogen-activated protein kinase 112100121
cytochrome P450 3A4 isoform 119800198
cGMP-dependent 3',5'-cyclic phosphodiesterase016016
Gamma-aminobutyric acid receptor subunit pi198239230
Monocarboxylate transporter 40102
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0707
cGMP-specific 3',5'-cyclic phosphodiesterase016017
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0202
Renin012113
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0707
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0608
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0608
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0609
Gamma-aminobutyric acid receptor subunit beta-1198239230
Gamma-aminobutyric acid receptor subunit delta198239230
Gamma-aminobutyric acid receptor subunit gamma-21982311232
Gamma-aminobutyric acid receptor subunit alpha-5198239230
Gamma-aminobutyric acid receptor subunit alpha-3198239230
Gamma-aminobutyric acid receptor subunit gamma-1198249231
Gamma-aminobutyric acid receptor subunit alpha-2198239230
Adenosine receptor A1226237
Gamma-aminobutyric acid receptor subunit alpha-4198239230
Gamma-aminobutyric acid receptor subunit gamma-3198239230
Adenosine receptor A30808
Adenosine receptor A2a032845
Adenosine receptor A2b05212
Adenosine receptor A2b09213
Gamma-aminobutyric acid receptor subunit alpha-6198239230
Adenosine receptor A1030644
Adenosine receptor A2a024437
Sodium-dependent serotonin transporter036340
Adenosine receptor A2a0303
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0608
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A011012
Gamma-aminobutyric acid receptor subunit alpha-11982511234
Gamma-aminobutyric acid receptor subunit beta-3198239230
Gamma-aminobutyric acid receptor subunit beta-21982311232
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0707
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B011012
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0505
cAMP-specific 3',5'-cyclic phosphodiesterase 4B022124
cAMP-specific 3',5'-cyclic phosphodiesterase 4D023125
cGMP-inhibited 3',5'-cyclic phosphodiesterase B018019
Voltage-dependent L-type calcium channel subunit alpha-1C037038
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0707
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C011012
cGMP-inhibited 3',5'-cyclic phosphodiesterase A019020
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0505
Phosphodiesterase 0101
GABA theta subunit198239230
Phosphodiesterase 0505
Gamma-aminobutyric acid receptor subunit epsilon198239230
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0505
Diacylglycerol kinase alpha0101
estrogen receptor 2 (ER beta)19700197
Prostaglandin G/H synthase 1 020023
Prostaglandin G/H synthase 2 011013
DNA repair and recombination protein RadA0033
Voltage-dependent calcium channel gamma-2 subunit17100171
Cytochrome P450 1A2071277
Cytochrome P450 2A6017321
Polyunsaturated fatty acid 5-lipoxygenase017025
Glutamate receptor 217731182
Cytochrome P450 2A50405
UDP-glucuronosyltransferase 1A1 015021
MAP kinase-activated protein kinase 2053237
nuclear factor erythroid 2-related factor 2 isoform 211800119
muscleblind-like protein 1 isoform 1650065
Rap guanine nucleotide exchange factor 4250025
67.9K protein11700117
Chain A, 2-oxoglutarate Oxygenase14500145
15-lipoxygenase, partial940094
phosphopantetheinyl transferase14700147
aldehyde dehydrogenase 1 family, member A126200262
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 112000120
lamin isoform A-delta1030300303
Smad310600106
Chain A, Putative fructose-1,6-bisphosphate aldolase840084
hypoxia-inducible factor 1 alpha subunit12000120
SMAD family member 213000130
SMAD family member 313000130
G18500185
alpha-galactosidase390039
euchromatic histone-lysine N-methyltransferase 235100351
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a13000130
Stimulator of interferon genes protein0011
peripheral myelin protein 2216400164
Trypsin0709
Interferon beta26500265
HLA class I histocompatibility antigen, B alpha chain 18500185
TAR DNA-binding protein 43941095
Stimulator of interferon genes protein0011
Inositol hexakisphosphate kinase 118500185
cytochrome P450 2C9, partial18500185
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10202
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10202
Chain A, Methyltransferase Wbdd0101
ATAD5 protein, partial15100151
NFKB1 protein, partial580058
Thrombopoietin550055
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)10300103
EWS/FLI fusion protein21500216
Parkin520052
cytochrome P450 2D6 isoform 1890089
cytochrome P450 2C19 precursor900090
serine/threonine-protein kinase mTOR isoform 1610061
survival motor neuron protein isoform d15600156
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform081423
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha0303
Serine/threonine-protein kinase PLK4073441
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta031215
Bromodomain-containing protein 40719
5-hydroxytryptamine receptor 4077279
Integrin beta-3723075
Integrin alpha-IIb722074
Neuronal acetylcholine receptor subunit alpha-41511330
Serine/threonine-protein kinase pim-10143551
Neuronal acetylcholine receptor subunit beta-21511330
Casein kinase II subunit alpha'0163349
Proteinase-activated receptor 10214
Bromodomain-containing protein 20303
Phosphatidylinositol 3-kinase regulatory subunit alpha0517
5-hydroxytryptamine receptor 2A075279
5-hydroxytryptamine receptor 2C086389
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0101
Type-1 angiotensin II receptor0639
5-hydroxytryptamine receptor 2B087390
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0111527
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform071322
Serine/threonine-protein kinase mTOR0121426
Serine/threonine-protein kinase mTOR0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0111325
Glycogen synthase kinase-3 beta0203454
D(1A) dopamine receptor304034
Serine/threonine-protein kinase PLK10142741
Casein kinase II subunit beta016016
Casein kinase II subunit alpha0181432
DNA-dependent protein kinase catalytic subunit010010
Mu-type opioid receptor025532
Serine-protein kinase ATM0404
Serine/threonine-protein kinase ATR031518
Bromodomain-containing protein 30303
Serine/threonine-protein kinase pim-3021416
Phosphoinositide 3-kinase regulatory subunit 50202
Serine/threonine-protein kinase PLK3091423
Serine/threonine-protein kinase PLK2081220
ATP-dependent phosphofructokinase15000150
PPM1D protein930093
Retinal dehydrogenase 10303
Signal transducer and activator of transcription 3013418
Protein cereblon018225
Chain A, Beta-lactamase11700117
lysosomal alpha-glucosidase preproprotein410041
interferon gamma precursor0008
atrial natriuretic peptide receptor 2 precursor380038
DNA dC->dU-editing enzyme APOBEC-3G isoform 1196025
Tubulin alpha-1A chain06310
Tubulin beta chain0639
Sex hormone-binding globulin001717
Cytochrome P450 1A1028332
Cytochrome P450 1B1033237
Tubulin beta-2B chain09112
Similar to alpha-tubulin isoform 1 07110
Similar to alpha-tubulin isoform 1 0709
acetylcholinesterase11900119
Sulfotransferase 1A1 0004
Sulfotransferase 1E10001
Sulfotransferase 1A10001
Sulfotransferase 2A10001
5-lipoxygenase 017017
Chain A, TYROSYL-DNA PHOSPHODIESTERASE14000140
ClpP160016
Fumarate hydratase10100101
polyprotein10100101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)560056
hexokinase-4 isoform 1110011
glucokinase regulatory protein110011
ras-related protein Rab-9A620062
eyes absent homolog 2 isoform a140014
lethal factor (plasmid)920092
Dual specificity mitogen-activated protein kinase kinase 7021315
Amyloid-beta precursor protein1129244
M-phase inducer phosphatase 10909
M-phase inducer phosphatase 20707
Ataxin-216800168
Single-stranded DNA cytosine deaminase9009
Dihydrofolate reductase 0707
Cationic trypsin0606
Dihydrofolate reductase0404
Dihydrofolate reductase013620
Tryptase beta-20101
Dihydrofolate reductase0708
m7GpppX diphosphatase0101
peripheral myelin protein 22 isoform 1790079
D(1A) dopamine receptor620062
Protein skinhead-10101
Monocarboxylate transporter 20303
Solute carrier family 22 member 20012012
Solute carrier family 22 member 6012012
apical membrane antigen 1, AMA1550055
Carbonic anhydrase 12037154
Carbonic anhydrase 10841110
Carbonic anhydrase 20955126
ATP-dependent translocase ABCB108217127
Calmodulin-109211
Androgen receptor121534
Pyruvate kinase PKM013114
Polyunsaturated fatty acid lipoxygenase ALOX150708
Polyunsaturated fatty acid lipoxygenase ALOX120607
Xanthine dehydrogenase/oxidase024024
Fatty acid synthase0808
Carbonic anhydrase 9046265
Aurora kinase B0153348
Dipeptidyl peptidase 30909
HSP40, subfamily A [Plasmodium falciparum 3D7]00010
Kynureninase0001
thyroid stimulating hormone receptor12900129
histone deacetylase 9 isoform 3480048
DNA topoisomerase type IB small subunit0011
DNA topoisomerase I 0011
Aryl hydrocarbon receptor0123
Nuclear receptor ROR-gamma794588
G-protein coupled receptor 840011
G-protein coupled receptor 840023
Thyroid hormone receptor alpha0538
Thyroid hormone receptor beta0538
Proliferating cell nuclear antigen0303
Thyroid hormone receptor beta0505
Retinoic acid receptor RXR-alpha091327
Peroxisome proliferator-activated receptor gamma0122439
Sodium/bile acid cotransporter09110
Solute carrier organic anion transporter family member 1C10303
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Penicillin Amidohydrolase0202
Chain B, Penicillin Amidohydrolase0202
Chain A, Protocatechuate 3,4-dioxygenase0011
Chain M, Protocatechuate 3,4-dioxygenase0011
Olfactory receptor class A-like protein 10011
endonuclease IV460046
RGS127007
alkaline phosphatase, intestinal0336
thioredoxin glutathione reductase590059
hypothetical protein, conserved250025
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0516
intestinal alkaline phosphatase precursor0516
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 15005
alkaline phosphatase, germ cell type preproprotein0336
POsterior Segregation001011
Prolyl 4-hydroxylase subunit alpha-10707
Sodium-dependent noradrenaline transporter 09214106
Zinc finger protein mex-5001011
Polyunsaturated fatty acid 5-lipoxygenase034136
Chain A, Retinoic acid receptor beta0011
Chain A, ATP-DEPENDENT DNA HELICASE Q1710071
thyrotropin-releasing hormone receptor270027
NPC intracellular cholesterol transporter 1 precursor490049
nuclear factor NF-kappa-B p105 subunit isoform 1160218
ubiquitin carboxyl-terminal hydrolase 2 isoform a510051
neuropeptide S receptor isoform A600060
Ornithine decarboxylase123017
Retinoic acid receptor alpha08922
Retinoic acid receptor beta08922
Retinoic acid receptor gamma 091024
Retinoic acid receptor RXR-beta07613
Cellular retinoic acid-binding protein 10305
Retinoic acid receptor RXR-gamma07613
potassium voltage-gated channel subfamily H member 2 isoform d12000120
transcriptional regulator ERG isoform 3380038
Tumor necrosis factor0426
cAMP-specific 3',5'-cyclic phosphodiesterase 4A021224
cGMP-dependent 3',5'-cyclic phosphodiesterase0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4C015015
cGMP-specific 3',5'-cyclic phosphodiesterase0303
hepatitis C virus polyprotein3003
ubiquitin-conjugating enzyme E2 N0808
Disintegrin and metalloproteinase domain-containing protein 17386044
Potassium voltage-gated channel subfamily H member 201091111
5-hydroxytryptamine receptor 40426
5-hydroxytryptamine receptor 4 0538
Genome polyprotein 0224
Polyphenol oxidase 2026137
Thiopurine S-methyltransferase0101
Succinate-semialdehyde dehydrogenase, mitochondrial0202
4-aminobutyrate aminotransferase, mitochondrial0304
Dihydropteroate synthase 0011
Chain A, Toluene-4-monooxygenase system protein A0101
[tau protein] kinase 0101
G2/mitotic-specific cyclin-B2010011
cAMP-dependent protein kinase catalytic subunit alpha0606
Beta-casein0101
Protein kinase C alpha type0505
Cyclin-dependent kinase 10222953
Protein kinase C delta type0505
Protein kinase C epsilon type0505
Protein kinase C zeta type0505
Replicase polyprotein 1ab0342054
Replicase polyprotein 1ab0542478
G2/mitotic-specific cyclin-B1017018
Glycogen synthase kinase-3 alpha0113344
Protein kinase C gamma type0505
Protein kinase C beta type0707
Protein kinase C eta type0505
G2/mitotic-specific cyclin-B3010011
Protein kinase C theta type0505
NPYLR7B001010
Replicase polyprotein 1ab0192039
Transient receptor potential cation channel subfamily A member 10459
bromodomain adjacent to zinc finger domain 2B800080
5-hydroxytryptamine receptor 2C026331
5-hydroxytryptamine receptor 2A040545
5-hydroxytryptamine receptor 1A0831097
5-hydroxytryptamine receptor 1B051253
5-hydroxytryptamine receptor 1D011213
5-hydroxytryptamine receptor 1F011213
5-hydroxytryptamine receptor 2B025429
5-hydroxytryptamine receptor 60527
Sodium-dependent serotonin transporter079887
5-hydroxytryptamine receptor 7 012214
5-hydroxytryptamine receptor 5A0527
5-hydroxytryptamine receptor 5B0527
5-hydroxytryptamine receptor 3A0729
5-hydroxytryptamine receptor 3B0729
Histamine H2 receptor049453
Histamine H1 receptor057968
Histamine H4 receptor0246
Histamine H4 receptor0347
Histamine H4 receptor013621
Histamine H3 receptor03111
Histamine H3 receptor013418
cytochrome P450 family 3 subfamily A polypeptide 426500265
cytochrome P450 2D619000190
nuclear receptor subfamily 1, group I, member 2670067
ATPase family AAA domain-containing protein 511900119
Estrogen receptor130741
Melatonin receptor type 1A0235
Melatonin receptor type 1B0235
Estrogen receptor beta120729
large T antigen015217
Tubulin beta-4A chain06615
Tubulin beta chain06615
Tubulin alpha-3C chain06615
Tubulin alpha-1B chain06615
Tubulin alpha-4A chain06615
Tubulin beta-4B chain06615
Tubulin beta-3 chain07616
Tubulin beta-2A chain06615
Tubulin beta-8 chain06615
Tubulin alpha-3E chain06615
Tubulin alpha-1A chain06615
Tubulin alpha-1C chain06615
Tubulin beta-6 chain06615
Tubulin beta-2B chain06615
Tubulin beta-1 chain06615
dual specificity tyrosine-phosphorylation-regulated kinase 1A0007
Cytochrome P450 3A401175137
Cytochrome P450 2D6080388
Potassium voltage-gated channel subfamily A member 20011
Potassium voltage-gated channel subfamily A member 30011
Potassium voltage-gated channel subfamily A member 60011
Amine oxidase [flavin-containing] A049051
Potassium voltage-gated channel subfamily A member 30505
Potassium voltage-gated channel subfamily A member 50415
Cytochrome P450 2C19054159
Potassium voltage-gated channel subfamily C member 10011
Beta-secretase 1020122
Potassium voltage-gated channel subfamily A member 10426
Polyunsaturated fatty acid lipoxygenase ALOX15028028
Oxoeicosanoid receptor 10314
Dihydrofolate reductase023025
Thymidylate synthase0708
Trifunctional purine biosynthetic protein adenosine-30202
Bifunctional purine biosynthesis protein ATIC0506
Folylpolyglutamate synthase, mitochondrial0107
Bifunctional purine biosynthesis protein ATIC0101
Signal transducer and activator of transcription 1-alpha/beta0213
lethal(3)malignant brain tumor-like protein 1 isoform I210021
Genome polyprotein0101
Mcl-10606
Myeloid cell leukemia sequence 1 (BCL2-related)0101
envelope glycoprotein0202
core protein, partial0303
polyunsaturated fatty acid lipoxygenase ALOX12280028
glyceraldehyde-3-phosphate dehydrogenase isoform 13205
eukaryotic translation initiation factor 4 gamma 1 isoform 40404
eukaryotic translation initiation factor 4E isoform 10404
Vif0506
Tat0404
dual specificity protein phosphatase 60202
tyrosine-protein phosphatase non-receptor type 7 isoform 20404
bcl-2-like protein 1 isoform Bcl-X(L)0101
Muscarinic acetylcholine receptor M1026736
Muscarinic acetylcholine receptor M3022732
Muscarinic acetylcholine receptor M4023733
Muscarinic acetylcholine receptor M5023733
Muscarinic acetylcholine receptor M2024836
Caspase-1110113
Bone morphogenetic protein receptor type-1B003232
ATP-dependent RNA helicase DDX3X002929
Pyridoxal kinase002930
Citron Rho-interacting kinase023335
Serine/threonine-protein kinase Chk1053439
Aurora kinase A073441
Cyclin-G-associated kinase063642
Ephrin type-B receptor 6003232
Peroxisomal acyl-coenzyme A oxidase 3002929
Receptor-interacting serine/threonine-protein kinase 2043337
Mitotic checkpoint serine/threonine-protein kinase BUB1002828
Dynamin-like 120 kDa protein, mitochondrial002929
Eukaryotic translation initiation factor 5B002020
Rho-associated protein kinase 2053237
Serine/threonine-protein kinase ULK1013132
Serine/threonine-protein kinase/endoribonuclease IRE1023234
Ribosomal protein S6 kinase alpha-5043438
U5 small nuclear ribonucleoprotein 200 kDa helicase002929
Ribosomal protein S6 kinase alpha-4013435
Serine/threonine-protein kinase 16013435
Serine/threonine-protein kinase 10023335
Serine/threonine-protein kinase D3053439
Structural maintenance of chromosomes protein 2002828
Mitogen-activated protein kinase kinase kinase 6013233
Mitogen-activated protein kinase kinase kinase kinase 4013334
Serine/threonine-protein kinase LATS1013334
Serine/threonine-protein kinase PAK 4043337
Tyrosine-protein kinase ABL10223660
Epidermal growth factor receptor0633598
High affinity nerve growth factor receptor023335
Guanine nucleotide-binding protein G(i) subunit alpha-2002222
ADP/ATP translocase 2002929
Protein kinase C beta type0103141
Insulin receptor0103344
Tyrosine-protein kinase Lck0203556
Tyrosine-protein kinase Fyn0283462
Glycogen phosphorylase, liver form022931
Tyrosine-protein kinase Fes/Fps013334
Adenine phosphoribosyltransferase002121
Tyrosine-protein kinase Yes053338
Tyrosine-protein kinase Lyn053338
Proto-oncogene tyrosine-protein kinase receptor Ret093342
Insulin-like growth factor 1 receptor083341
Signal recognition particle receptor subunit alpha002424
Cytochrome c1, heme protein, mitochondrial002929
Hepatocyte growth factor receptor073340
Tyrosine-protein kinase HCK073340
Platelet-derived growth factor receptor beta0153349
Serine/threonine-protein kinase A-Raf032932
Glycogen phosphorylase, brain form012930
Breakpoint cluster region protein063139
Fibroblast growth factor receptor 1093343
DNA topoisomerase 2-alpha0102648
Cyclin-dependent kinase 40113244
ADP/ATP translocase 3002929
Inosine-5'-monophosphate dehydrogenase 2042529
Proto-oncogene tyrosine-protein kinase Src0193353
cAMP-dependent protein kinase type II-alpha regulatory subunit002727
Serine/threonine-protein kinase B-raf0133651
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform013435
Ribosyldihydronicotinamide dehydrogenase [quinone]0113142
Tyrosine-protein kinase Fer013334
Protein kinase C alpha type0183353
cAMP-dependent protein kinase catalytic subunit alpha063339
General transcription and DNA repair factor IIH helicase subunit XPD002929
Ras-related protein Rab-6A002727
Ephrin type-A receptor 1013233
Multifunctional protein ADE2002929
cAMP-dependent protein kinase catalytic subunit gamma052530
cAMP-dependent protein kinase catalytic subunit beta053338
Ferrochelatase, mitochondrial003030
Ribosomal protein S6 kinase beta-1033033
Tyrosine-protein kinase JAK10163554
Beta-adrenergic receptor kinase 1023234
Probable ATP-dependent RNA helicase DDX6002828
Mitogen-activated protein kinase 3 083342
MAP/microtubule affinity-regulating kinase 3013334
Deoxycytidine kinase012935
Mitogen-activated protein kinase 10163349
Ephrin type-A receptor 2033336
Ephrin type-B receptor 2033437
Non-receptor tyrosine-protein kinase TYK2093547
Wee1-like protein kinase003333
Heme oxygenase 2002929
DnaJ homolog subfamily A member 1002929
RAC-alpha serine/threonine-protein kinase0103444
RAC-beta serine/threonine-protein kinase013334
Dual specificity protein kinase TTK012526
DNA replication licensing factor MCM4002828
Dual specificity mitogen-activated protein kinase kinase 2093342
Receptor-type tyrosine-protein kinase FLT30233357
Bone morphogenetic protein receptor type-1A013334
Activin receptor type-1B013334
TGF-beta receptor type-1033336
TGF-beta receptor type-2003333
Tyrosine-protein kinase CSK043337
Glycine--tRNA ligase002929
Protein kinase C iota type043337
Exosome RNA helicase MTR4002929
Tyrosine-protein kinase Tec033336
Tyrosine-protein kinase ABL2043337
Tyrosine-protein kinase FRK023335
G protein-coupled receptor kinase 6022022
Tyrosine-protein kinase SYK0113748
26S proteasome regulatory subunit 6B012930
Mitogen-activated protein kinase 8083644
Mitogen-activated protein kinase 9083543
Dual specificity mitogen-activated protein kinase kinase 3013334
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha102425
Casein kinase I isoform alpha053137
Casein kinase I isoform delta043338
Elongation factor Tu, mitochondrial002929
Casein kinase I isoform epsilon033538
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial002929
Dual specificity protein kinase CLK1013233
Dual specificity protein kinase CLK2013435
Dual specificity protein kinase CLK3012526
Cyclin-dependent kinase 7053339
Cyclin-dependent kinase 9073341
Ras-related protein Rab-27A002727
Interleukin-1 receptor-associated kinase 1013233
Ribosomal protein S6 kinase alpha-3043438
Serine/threonine-protein kinase Nek2033336
Serine/threonine-protein kinase Nek3013233
Dual specificity mitogen-activated protein kinase kinase 6013334
LIM domain kinase 1013334
LIM domain kinase 2013334
Mitogen-activated protein kinase 100163450
Tyrosine--tRNA ligase, cytoplasmic002828
5'-AMP-activated protein kinase subunit gamma-1013234
Ephrin type-B receptor 3013334
Ephrin type-A receptor 5013334
Ephrin type-B receptor 4053338
Ephrin type-A receptor 4013334
Adenylate kinase 2, mitochondrial002932
Adenosine kinase002829
Ras-related protein Rab-10002929
Actin-related protein 3012829
Actin-related protein 2002727
GTP-binding nuclear protein Ran002929
Casein kinase I isoform gamma-2022931
Cyclin-dependent kinase 3023134
Cyclin-dependent kinase 60122942
Cyclin-dependent-like kinase 5 0113345
Cyclin-dependent kinase 16023437
Cyclin-dependent kinase 17023336
ATP-dependent 6-phosphofructokinase, platelet type002929
Dual specificity mitogen-activated protein kinase kinase 10113344
DNA topoisomerase 2-beta023041
Protein kinase C theta type073441
Activin receptor type-1013334
Macrophage-stimulating protein receptor013233
Focal adhesion kinase 1043337
Protein kinase C delta type083543
Tyrosine-protein kinase BTK063440
Activated CDC42 kinase 1013334
Epithelial discoidin domain-containing receptor 1033437
Mitogen-activated protein kinase kinase kinase kinase 2003232
Tyrosine-protein kinase Mer032225
Serine/threonine-protein kinase 4013435
5'-AMP-activated protein kinase catalytic subunit alpha-1013537
Dual specificity mitogen-activated protein kinase kinase 5013233
Mitogen-activated protein kinase 7013334
Serine/threonine-protein kinase 3013334
Mitogen-activated protein kinase kinase kinase 1013233
Integrin-linked protein kinase002828
Rho-associated protein kinase 1053237
Non-receptor tyrosine-protein kinase TNK1013334
Calcium/calmodulin-dependent protein kinase type II subunit gamma023335
Calcium/calmodulin-dependent protein kinase type II subunit delta023335
Dual specificity tyrosine-phosphorylation-regulated kinase 1A043236
Activin receptor type-2B003333
Bone morphogenetic protein receptor type-2013334
Protein-tyrosine kinase 6023335
cGMP-dependent protein kinase 1 013334
Cyclin-dependent kinase 13023235
Inhibitor of nuclear factor kappa-B kinase subunit epsilon013334
Protein-tyrosine kinase 2-beta023335
Maternal embryonic leucine zipper kinase033336
Structural maintenance of chromosomes protein 1A002727
Chromodomain-helicase-DNA-binding protein 4002626
Serine/threonine-protein kinase 38012122
Ephrin type-A receptor 7012930
Delta(24)-sterol reductase002727
Ribosomal protein S6 kinase alpha-1043337
Dual specificity testis-specific protein kinase 1013031
Myosin light chain kinase, smooth muscle023335
Serine/threonine-protein kinase STK11013334
Serine/threonine-protein kinase N1023335
Serine/threonine-protein kinase N2023335
Calcium/calmodulin-dependent protein kinase type IV013334
Mitogen-activated protein kinase kinase kinase 11023335
Discoidin domain-containing receptor 2053338
AP2-associated protein kinase 1033437
Myosin light chain kinase 3013233
Putative heat shock protein HSP 90-beta 2002828
Rab-like protein 3002424
Serine/threonine-protein kinase MRCK alpha013334
Serine/threonine-protein kinase MRCK gamma013031
Acyl-CoA dehydrogenase family member 10002626
Serine/threonine-protein kinase N3012526
Serine/threonine-protein kinase ULK3013233
Uncharacterized protein FLJ45252002929
Acyl-CoA dehydrogenase family member 11002727
Serine/threonine-protein kinase/endoribonuclease IRE2012829
Serine/threonine-protein kinase MARK2013435
ATP-dependent RNA helicase DHX30002222
Serine/threonine-protein kinase TAO1013233
STE20-related kinase adapter protein alpha002929
AarF domain-containing protein kinase 1002929
ATP-dependent RNA helicase DDX42002222
Mitogen-activated protein kinase kinase kinase kinase 3013334
MAP kinase-activated protein kinase 5053237
Misshapen-like kinase 1012627
Atypical kinase COQ8A, mitochondrial003434
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma003232
Mitogen-activated protein kinase 15013334
Serine/threonine-protein kinase Nek9013334
ATP-dependent RNA helicase DDX1002929
Mitogen-activated protein kinase kinase kinase kinase 1013334
MAP/microtubule affinity-regulating kinase 4013233
Calcium/calmodulin-dependent protein kinase type 1G011920
Serine/threonine-protein kinase Nek1013334
PAS domain-containing serine/threonine-protein kinase012425
Calcium/calmodulin-dependent protein kinase kinase 2013435
EKC/KEOPS complex subunit TP53RK002929
Dual specificity testis-specific protein kinase 2001717
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase003333
Mitogen-activated protein kinase kinase kinase 5013334
Mitogen-activated protein kinase kinase kinase 3013233
Eukaryotic translation initiation factor 2-alpha kinase 1003232
Nucleolar GTP-binding protein 1002929
Serine/threonine-protein kinase D2013334
NUAK family SNF1-like kinase 2013132
RNA cytidine acetyltransferase002929
Serine/threonine-protein kinase SIK2013334
STE20-like serine/threonine-protein kinase 013435
Serine/threonine-protein kinase TAO3013233
dCTP pyrophosphatase 1022931
Casein kinase I isoform gamma-1023436
Phenylalanine--tRNA ligase beta subunit002929
BMP-2-inducible protein kinase003434
Obg-like ATPase 1002121
Midasin002929
Interleukin-1 receptor-associated kinase 4013233
Mitogen-activated protein kinase kinase kinase 20013334
Cyclin-dependent kinase 12022932
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13002828
Serine/threonine-protein kinase pim-2012425
Serine/threonine-protein kinase 26013334
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial002626
Serine/threonine-protein kinase NLK023436
5'-AMP-activated protein kinase subunit gamma-2003031
Serine/threonine-protein kinase TBK1053237
Septin-9002929
Ribosomal protein S6 kinase alpha-6013334
Serine/threonine-protein kinase TAO2013233
Long-chain-fatty-acid--CoA ligase 5002222
Serine/threonine-protein kinase ICK013132
RAC-gamma serine/threonine-protein kinase023335
Serine/threonine-protein kinase 38-like012627
Serine/threonine-protein kinase SIK3013233
Mitogen-activated protein kinase kinase kinase 2013233
Mitogen-activated protein kinase kinase kinase kinase 5013334
Receptor-interacting serine/threonine-protein kinase 3022931
Serine/threonine-protein kinase MRCK beta013334
Interleukin-1 receptor-associated kinase 3003333
Serine/threonine-protein kinase 24012930
Casein kinase I isoform gamma-3013334
Mitogen-activated protein kinase kinase kinase 4003333
Nicotinamide N-methyltransferase0202
Solute carrier organic anion transporter family member 2A103010
Histone acetyltransferase p3000505
Histone deacetylase 1026534
Histone deacetylase 6024431
Leukotriene B4 receptor 1111114
Rap guanine nucleotide exchange factor 3370037
NPC1-like intracellular cholesterol transporter 10022
Substance-P receptor016218
Substance-P receptor020022
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Coagulation factor VII0909
Tissue factor013013
Transient receptor potential cation channel subfamily A member 1031521
Bile salt export pump03450345
Sigma non-opioid intracellular receptor 1067269
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0505
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0202
Solute carrier organic anion transporter family member 1B3043052
Solute carrier organic anion transporter family member 1B1046056
histone-lysine N-methyltransferase 2A isoform 2 precursor420042
ATP-binding cassette sub-family C member 302270227
Multidrug resistance-associated protein 402280235
pyruvate kinase PKM isoform a110011
Lactoylglutathione lyase013013
caspase 7, apoptosis-related cysteine protease690069
caspase-3690069
Caspase-7360036
caspase-3360036
Solute carrier family 22 member 6028033
UDP-glucuronosyltransferase 1A903011
Bile salt export pump050050
Cytochrome P450 2B10305
Cytochrome P450 1A10103
Myoglobin0101
Prostaglandin G/H synthase 1036340
Carbonic anhydrase 3024135
UDP-glucuronosyltransferase 1-6012015
Arachidonate 5-lipoxygenase-activating protein0516
Carbonic anhydrase 4053167
Prostaglandin G/H synthase 1048048
Carbonic anhydrase 6034148
Carbonic anhydrase 5A, mitochondrial033252
Prostaglandin G/H synthase 20551473
Carbonic anhydrase 7036150
Cytochrome P450 2J2048050
Canalicular multispecific organic anion transporter 102150216
Carbonic anhydrase 15026034
Carbonic anhydrase 13023035
Carbonic anhydrase 14024140
Carbonic anhydrase 5B, mitochondrial027144
toxin B0001
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0003
Carbonic anhydrase 0808
GALC protein270027
Carbonic anhydrase 0404
Carbonic anhydrase 0505
Carbonic anhydrase0505
Carbonic anhydrase0303
Prolyl endopeptidase0202
Carbonic anhydrase-related protein 110103
Glycogen phosphorylase, muscle form0808
Carbonic anhydrase 20314
Cathepsin B0101
Steryl-sulfatase0405
Cytochrome P450 2C8022025
Androgen receptor057057
Translocator protein09313
Cytochrome P450 2B6016222
Carbonic anhydrase 5A, mitochondrial0303
Serum paraoxonase/arylesterase 1010010
Dipeptidyl peptidase 4019121
Endochitinase0101
Delta-type opioid receptor024433
Delta-type opioid receptor019526
Mu-type opioid receptor026736
Carbonic anhydrase019025
Kappa-type opioid receptor021330
Carbonic anhydrase0202
Corticosteroid 11-beta-dehydrogenase isozyme 10314
Carbonic anhydrase03010
D(2) dopamine receptor027534
Cholinesterase018119
Carbonic anhydrase 0404
Fatty-acid amide hydrolase 128010
Beta-carbonic anhydrase 10606
Carbonic anhydrase 20404
Glutamate receptor ionotropic, NMDA 2B022334
Squalene synthase0505
Neuronal acetylcholine receptor subunit alpha-707311
Carbonic anhydrase0707
Carbonic anhydrase, alpha family 0606
Carbonic anhydrase 04011
Carbonic anhydrase 3010010
Carbonic anhydrase05013
Carbonic anhydrase04012
Carbonic anhydrase 0404
Sigma intracellular receptor 2014014
Delta carbonic anhydrase0404
Sigma non-opioid intracellular receptor 1018321
Renin0202
Carbonic anhydrase 03010
Endochitinase A10101
Multidrug resistance-associated protein 10202
Carbonic anhydrase 13011116
Carbonic anhydrase 407011
Acidic mammalian chitinase0101
Carbonic anhydrase 70101
Carbonic anhydrase 0505
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Free fatty acid receptor 30022
Free fatty acid receptor 20112
Fibrinogen C domain-containing protein 10202
Prostaglandin E synthase0808
Prolyl endopeptidase0707
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10617
dopamine D1 receptor240024
pregnane X receptor460046
Histone deacetylase 3020326
Histone deacetylase 4016221
Histone deacetylase 7016322
Histone deacetylase 2023531
Polyamine deacetylase HDAC10014320
Histone deacetylase 11 015220
Histone deacetylase 8020427
Histone deacetylase 9015220
Histone deacetylase 5017222
Putative glycosyltransferase WbgO0001
Killer cell lectin-like receptor subfamily B member 1A0101
Early activation antigen CD690101
Acetylcholinesterase054156
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0022
serine-protein kinase ATM isoform a120012
parathyroid hormone/parathyroid hormone-related peptide receptor precursor650065
huntingtin isoform 2540054
glycogen synthase kinase-3 alpha0004
Choline O-acetyltransferase 0203
Chain A, Peptide deformylase 1B, chloroplastic0101
Chain A, Peptide deformylase 1B, chloroplastic0101
Urokinase-type plasminogen activator010010
Interstitial collagenase09110
Neprilysin0202
72 kDa type IV collagenase014014
Stromelysin-1010212
Neprilysin0303
Angiotensin-converting enzyme 014116
Aminopeptidase N0606
Peptide deformylase0101
Peptide deformylase0101
Meprin A subunit beta0101
Peptide deformylase 1A, chloroplastic/mitochondrial0101
Peptide deformylase, mitochondrial0202
Peptide deformylase 0101
Chain E, Purine nucleoside phosphorylase0101
Thymidine kinase 0506
hemoglobin subunit beta130013
atrial natriuretic peptide receptor 1 precursor240024
Solute carrier family 22 member 1 051064
Purine nucleoside phosphorylase0608
Thymidine kinase, cytosolic09017
POU domain, class 2, transcription factor 20103
Purine nucleoside phosphorylase0044
Solute carrier family 22 member 6022033
Thymidine kinase 0101
Solute carrier family 22 member 8020030
Thymidine kinase0203
60 kDa chaperonin019019
60 kDa heat shock protein, mitochondrial023023
Aspartate aminotransferase, cytoplasmic0101
Glycine receptor subunit alpha-10077
Spike glycoprotein164719190
10 kDa heat shock protein, mitochondrial023023
Thiosulfate sulfurtransferase022022
60 kDa chaperonin 025025
10 kDa chaperonin 025025
Phosphoribosyl pyrophosphate synthase-associated protein 20102
Adenylate kinase isoenzyme 10003
Adenosine deaminase 0206
Capsid protein 0145
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
tumor susceptibility gene 101 protein7007
Heat shock protein HSP 90-beta05411
Protein mono-ADP-ribosyltransferase PARP150303
Leucine-rich repeat serine/threonine-protein kinase 2041216
Chain A, Membrane lipoprotein tmpC0033
Chain A, Membrane lipoprotein tmpC0033
Chain A, Membrane lipoprotein tmpC0033
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced4004
glycogen synthase kinase-3 beta isoform 1001313
high affinity choline transporter 1 isoform a0404
Sodium/nucleoside cotransporter 10505
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 7011516
Sodium/nucleoside cotransporter 20505
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0404
Receptor tyrosine-protein kinase erbB-20271542
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha06815
Adenosine receptor A3052458
Heat shock 70 kDa protein 1A 0213
Heat shock cognate 71 kDa protein0022
Endoplasmin0225
Inosine-5'-monophosphate dehydrogenase 1 0404
Fibroblast growth factor receptor 2021417
Fibroblast growth factor receptor 4021417
Fibroblast growth factor receptor 3021417
Streptavidin0022
Adenosylhomocysteinase0207
Adenylate kinase 2, mitochondrial0203
Adenylate kinase isoenzyme 1 0203
Phosphatidylinositol 4-kinase alpha0607
Adenosine receptor A10314
Equilibrative nucleoside transporter 20404
Phosphatidylinositol 4-kinase type 2-beta0506
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10808
Phosphatidylinositol 4-kinase type 2-alpha0506
Solute carrier family 28 member 30505
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta061320
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
ATP-dependent molecular chaperone HSP820001
2-dehydropantoate 2-reductase0246
Endoplasmic reticulum chaperone BiP0213
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0404
Mu-type opioid receptor0461166
Delta-type opioid receptor038956
Kappa-type opioid receptor039857
Endoplasmin0213
P2Y purinoceptor 20022
P2X purinoceptor 10022
P2Y purinoceptor 10022
P2Y purinoceptor 10022
P2X purinoceptor 10112
P2X purinoceptor 40123
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Heat shock protein 75 kDa, mitochondrial0202
P2Y purinoceptor 60022
P2Y purinoceptor 110022
P2Y purinoceptor 120314
Sensor protein kinase WalK0101
P2X purinoceptor 20022
Transient receptor potential cation channel subfamily M member 20415
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20012
Alcohol dehydrogenase E chain0202
Alcohol dehydrogenase S chain0202
L-lactate dehydrogenase A chain0415
Fructose-1,6-bisphosphatase 10202
Alkaline phosphatase, tissue-nonspecific isozyme0708
Fructose-1,6-bisphosphatase 10506
Inosine-5'-monophosphate dehydrogenase0101
Amine oxidase [flavin-containing] B019019
5'-nucleotidase0203
GTP:AMP phosphotransferase AK3, mitochondrial0001
5'-AMP-activated protein kinase catalytic subunit alpha-2011618
Glycine--tRNA ligase0101
Adenosine deaminase-like protein0001
Protease 016632
Histamine H3 receptor0315
5'-AMP-activated protein kinase subunit gamma-30012
5'-AMP-activated protein kinase subunit beta-10135
Phospholipase D20101
Aromatase043047
Estrogen-related receptor gamma0224
Phospholipase D10202
Thymidylate synthase 0203
Chain A, Breast cancer type 1 susceptibility protein8008
pyruvate kinase PKM isoform b120012
Macrophage colony-stimulating factor 1 receptor081422
Dipeptidyl peptidase 40707
Protein-glutamine gamma-glutamyltransferase 20707
Tyrosine-protein kinase JAK30221743
Dynamin-10101
Receptor-type tyrosine-protein phosphatase eta0505
Receptor protein-tyrosine kinase 0404
Tyrosyl-DNA phosphodiesterase 10606
WRN170017
chaperonin-containing TCP-1 beta subunit homolog4004
Tyrosine-protein kinase JAK20182142
Glutamate receptor ionotropic, NMDA 1 020432
Glutamate receptor ionotropic, NMDA 2A 017227
Glutamate receptor ionotropic, NMDA 2C017228
Histidine triad nucleotide-binding protein 10011
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0206
Proton-coupled amino acid transporter 1012013
Adenosine deaminase0001
Methionine aminopeptidase0101
Beta-2 adrenergic receptor0231337
Beta-1 adrenergic receptor0321143
Beta-3 adrenergic receptor0261036
Beta-2 adrenergic receptor 0149
Beta-2 adrenergic receptor08919
Corticosteroid-binding globulin013013
Mineralocorticoid receptor 17615
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A109016
Pepsin A0303
Renin-1 0101
Renin 0202
Cathepsin D 0303
Renin 0101
Protease 012315
retinoic acid receptor alpha isoform 10101
retinoic acid receptor RXR-alpha isoform a0101
Retinoic acid receptor alpha0336
Retinoic acid receptor gamma0235
Retinoic acid receptor beta0235
Nuclear receptor subfamily 4 group A member 10022
Cellular retinoic acid-binding protein 20033
Retinoic acid receptor RXR-alpha0358
Retinoic acid receptor RXR-beta0268
Retinoic acid receptor RXR-gamma0268
Type-2 angiotensin II receptor0729
Oxysterols receptor LXR-beta0258
Cellular retinoic acid-binding protein 10033
Retinoic acid receptor RXR-alpha0022
Oxysterols receptor LXR-alpha0258
DNA topoisomerase 109221
Class A sortase SrtA 0303
Transient receptor potential cation channel subfamily V member 10538
Procathepsin L0141933
Cathepsin B0303
Transient receptor potential cation channel subfamily A member 10055
Transient receptor potential cation channel subfamily V member 104311
Cysteine protease 0303
Mitochondrial 2-oxodicarboxylate carrier0202
Thioredoxin reductase 1, cytoplasmic0808
Bifunctional epoxide hydrolase 2017017
P2Y purinoceptor 12012113
Thioredoxin reductase 2, mitochondrial0808
interleukin 8580058
Hypoxanthine-guanine phosphoribosyltransferase0005
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase015120
Shiga toxin subunit A0202
Chain A, Xcogt0011
Chain A, Xcogt0011
Chain A, Xcogt0011
Amine oxidase [flavin-containing] B040244
Tissue alpha-L-fucosidase0505
Botulinum neurotoxin type A 0606
Neutrophil cytosol factor 10202
Nitric oxide synthase, endothelial0303
Nitric oxide synthase, brain0708
Nitric oxide synthase, brain 0506
Nitric oxide synthase, inducible0417
Tyrosine-protein kinase 0011
Indoleamine 2,3-dioxygenase 1018120
phospholipase A2 precursor0202
cysteine protease ATG4B isoform a0202
DNA dC->dU-editing enzyme APOBEC-3F isoform a140014
Free fatty acid receptor 10055
Nuclear receptor subfamily 1 group I member 2012223
Prostaglandin G/H synthase 2022023
Free fatty acid receptor 40022
Carboxylic ester hydrolase 0101
Cytochrome P450 3A60101
UDP-glucuronosyltransferase 2B7011022
Substance-K receptor040040
UDP-glucuronosyltransferase 1A4010021
Sodium-dependent dopamine transporter023225
Thromboxane-A synthase 023023
Multidrug resistance-associated protein 1 012117
UDP-glucuronosyltransferase 2B10 0909
5-hydroxytryptamine receptor 1A0221133
Alpha-2A adrenergic receptor080691
Beta-2 adrenergic receptor010115
Alpha-2B adrenergic receptor074483
Beta-1 adrenergic receptor010419
Alpha-2C adrenergic receptor062471
Alpha-1D adrenergic receptor062470
Alpha-1A adrenergic receptor017526
Alpha-1B adrenergic receptor012420
Prostaglandin E2 receptor EP3 subtype0303
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin E2 receptor EP1 subtype0303
Prostacyclin receptor0639
Nuclear receptor subfamily 4 group A member 20099
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0314
Solute carrier organic anion transporter family member 2A10308
Solute carrier organic anion transporter family member 2B10203
Solute carrier organic anion transporter family member 3A10001
Lysosomal acid glucosylceramidase0112
isocitrate dehydrogenase 1, partial160016
Valosin-containing protein0303
Spike glycoprotein071926
Vpr210021
streptokinase A precursor002424
hypothetical protein SA14220202
Gamma-aminobutyric acid receptor subunit pi016016
Gamma-aminobutyric acid receptor subunit delta016016
Transmembrane protease serine 2091928
Group 10 secretory phospholipase A20101
Phospholipase A20101
Estrogen receptor001718
Neutrophil elastase018018
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-10101
Poly [ADP-ribose] polymerase 10404
Replicase polyprotein 1a0142034
Replicase polyprotein 1ab081927
Phospholipase A2, membrane associated0304
Matrix metalloproteinase-9013114
Gamma-aminobutyric acid receptor subunit alpha-1020828
Vascular endothelial growth factor A0011
Tyrosine-protein phosphatase non-receptor type 1030134
Gamma-aminobutyric acid receptor subunit beta-1017320
Gamma-aminobutyric acid receptor subunit gamma-2019726
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-10101
Gamma-aminobutyric acid receptor subunit beta-3019423
Gamma-aminobutyric acid receptor subunit alpha-5018523
Gamma-aminobutyric acid receptor subunit alpha-3018422
D(3) dopamine receptor070378
Cytosolic phospholipase A20202
Gamma-aminobutyric acid receptor subunit alpha-2018422
Gamma-aminobutyric acid receptor subunit beta-2018725
Cannabinoid receptor 20235
Gamma-aminobutyric acid receptor subunit alpha-4017219
Placenta growth factor0011
Gamma-aminobutyric acid receptor subunit epsilon016016
Delta-type opioid receptor0101
5-hydroxytryptamine receptor 1D0101
Gamma-aminobutyric acid receptor subunit alpha-6017219
Estrogen receptor beta001718
Reverse transcriptase/RNaseH 016942
Gamma-aminobutyric acid receptor subunit gamma-1016016
Gamma-aminobutyric acid receptor subunit gamma-3016016
Angiotensin-converting enzyme 2 092029
Poly [ADP-ribose] polymerase 20101
Gamma-aminobutyric acid receptor subunit theta016016
M1-family alanyl aminopeptidase0505
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Membrane primary amine oxidase 0404
Prothrombin013419
Coagulation factor X0909
Plasminogen09211
Tissue-type plasminogen activator0808
Coagulation factor XI0101
Plasma kallikrein0108
Vitamin K-dependent protein C0404
Urokinase-type plasminogen activator0505
Trypsin-10707
Trypsin-20707
Sodium/hydrogen exchanger 10101
Sodium/hydrogen exchanger 10202
Sodium/hydrogen exchanger 30202
Trypsin-30707
Amiloride-sensitive sodium channel subunit alpha0101
5-hydroxytryptamine receptor 7022022
Sodium/hydrogen exchanger 20202
Acid-sensing ion channel 10303
Sodium channel protein type 5 subunit alpha023023
Sodium/hydrogen exchanger 50202
Solute carrier family 22 member 1021027
Solute carrier family 22 member 2018020
Acid-sensing ion channel 30101
Sodium/hydrogen exchanger0101
Chain A, PLASMINOGEN0022
Chain A, PLASMINOGEN0022
Chain A, Apolipoprotein0011
Sterol O-acyltransferase 10303
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Triosephosphate isomerase0303
Steroid 17-alpha-hydroxylase/17,20 lyase0909
Cholesterol side-chain cleavage enzyme, mitochondrial0101
Aromatase0224
Cytochrome P450 11B2, mitochondrial0101
aryl hydrocarbon receptor nuclear translocator0003
transforming acidic coiled-coil-containing protein 30003
Glutaminyl-peptide cyclotransferase0808
Guanine deaminase0405
Gamma-aminobutyric acid receptor subunit rho-10123
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 31204
Solute carrier family 15 member 1021021
Glutamate receptor 40101
Solute carrier family 15 member 10808
Solute carrier family 15 member 2013014
Dihydrofolate reductase0608
Dihydrofolate reductase07010
Folylpolyglutamate synthase, mitochondrial0206
Solute carrier organic anion transporter family member 1A30309
Nicotinate phosphoribosyltransferase011011
ORF730033
Voltage-dependent L-type calcium channel subunit alpha-1C011011
Solute carrier organic anion transporter family member 1A408015
Voltage-dependent L-type calcium channel subunit alpha-1F028028
Lysine-specific demethylase PHF20101
Thyroid hormone receptor alpha0101
ATP-dependent translocase ABCB1025025
Aldo-keto reductase family 1 member B1087087
Muscarinic acetylcholine receptor M2058568
Muscarinic acetylcholine receptor M4055260
Muscarinic acetylcholine receptor M5052156
Muscarinic acetylcholine receptor M1067780
D(2) dopamine receptor055465
Alpha-1B adrenergic receptor081889
Lethal factor0303
Muscarinic acetylcholine receptor M3058364
ATP-dependent translocase ABCB1026532
D(1A) dopamine receptor052359
D(4) dopamine receptor027133
Carnitine O-palmitoyltransferase 2, mitochondrial0303
Endothelin-1 receptor010111
Lysine-specific demethylase 5A0303
B2 bradykinin receptor0619
Melanocortin receptor 4010010
C-8 sterol isomerase0707
Melanocortin receptor 5014014
Sodium channel protein type 1 subunit alpha010010
Sodium channel protein type 4 subunit alpha011014
Squalene synthase0101
C-C chemokine receptor type 20909
Melanocortin receptor 3010010
Alpha-1A adrenergic receptor084993
5-hydroxytryptamine receptor 6055158
Carnitine O-palmitoyltransferase 1, liver isoform0303
C-C chemokine receptor type 40606
Sodium channel protein type 7 subunit alpha0707
Voltage-dependent L-type calcium channel subunit alpha-1D 028028
Sodium-dependent dopamine transporter 066470
Voltage-dependent L-type calcium channel subunit alpha-1S028028
Squalene monooxygenase0303
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0819
Sodium channel protein type 9 subunit alpha013013
Lysine-specific demethylase 7A0202
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Sodium channel protein type 2 subunit alpha011011
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0347
Sodium channel protein type 3 subunit alpha012012
Sodium channel protein type 11 subunit alpha0707
Histone lysine demethylase PHF80202
Sodium channel protein type 8 subunit alpha0707
Sodium channel protein type 10 subunit alpha0808
Albumin001313
Angiotensin-converting enzyme043044
D(1B) dopamine receptor0609
Histamine H1 receptor010111
UDP-glucuronosyltransferase 1A30008
Voltage-dependent N-type calcium channel subunit alpha-1B0415
Nuclear receptor subfamily 3 group C member 3 031031
NEDD8-activating enzyme E1 regulatory subunit isoform a0202
NEDD8-conjugating enzyme Ubc120202
Potassium channel subfamily K member 207714
Alpha-2B adrenergic receptor027835
Voltage-dependent L-type calcium channel subunit alpha-1C0808
Alpha-2C adrenergic receptor027835
Alpha-2A adrenergic receptor027835
Potassium channel subfamily K member 2 0202
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Beta-lactamase 0104
Beta-lactamase 0106
Beta-lactamase 0006
Beta-lactamase 0108
Beta-lactamase 0005
Beta-lactamase SHV-10105
Beta-lactamase SHV-10208
Beta-lactamase0108
B2 metallo-beta-lactamase 0006
Solute carrier family 15 member 2010010
Beta-lactamase 0105
Beta-lactamase 0004
Beta-lactamase 0105
Beta-lactamase 0006
Synaptojanin-20202
Synaptojanin-10202
tumor necrosis factor7007
Chain A, Mutant Al2 6e7p9g0011
Beta-lactamase 0407
Beta-lactamase 0207
Beta-lactamase 0106
Metallo-beta-lactamase type 20118
Metallo-beta-lactamase VIM-11 0005
Metallo-beta-lactamase VIM-20005
Beta-lactamase 0005
Metallo-beta-lactamase0005
Beta-lactamase 0207
Beta-lactamase OXA-70006
Angiopoietin-1 receptor061622
Beta-lactamase 0004
Beta-lactamase 0004
Beta-lactamase 0004
Metallo-beta-lactamase VIM-130106
Efflux transporter 0104
Beta-lactamase 0106
Beta-lactamase Toho-10004
Beta-lactamase 0104
Class D beta-lactamase0105
Metallo-beta-lactamase0004
Beta-lactamase 0106
Beta-lactamase 0115
Metallo-b-lactamase 0009
Carbapenem-hydrolyzing beta-lactamase KPC0209
Beta-lactamase class B VIM-2 01111
Beta-lactamase VIM-1 0106
Beta-lactamase 0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0607
Amine oxidase [flavin-containing] A 016117
C-C chemokine receptor type 50505
Nuclear factor NF-kappa-B p105 subunit011011
Hexokinase-20101
Bile acid receptor0426
Chain A, retinol dehydratase0101
Glucose-6-phosphate 1-dehydrogenase012012
G-protein coupled bile acid receptor 101910
Acetylcholinesterase024024
Atrial natriuretic peptide receptor 30202
Type-1A angiotensin II receptor 1539
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor1607
Type-1 angiotensin II receptor08416
Type-2 angiotensin II receptor110011
Chain A, BCL-2-RELATED PROTEIN A10078
PAX800013
Hsf1 protein0089
heat shock protein 900066
caspase recruitment domain family, member 150202
receptor-interacting serine/threonine-protein kinase 2 isoform 10202
bcl-2-like protein 11 isoform 10077
Bcl-2-like protein 110001
Glucose transporter0303
Hexose transporter 1 0303
Solute carrier family 2, facilitated glucose transporter member 10617
Beta lactamase (plasmid)0303
Histamine H1 receptor07616
microphthalmia-associated transcription factor isoform 90303
NAD-dependent protein deacylase sirtuin-5, mitochondrial0709
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0202
Chain A, Transthyretin0055
Chain A, Transthyretin0055
Chain A, Transthyretin0055
Chain A, Transthyretin0055
Chain B, Transthyretin0055
Chain A, Transthyretin0055
Chain B, Transthyretin0055
Chain A, Casein kinase II subunit alpha0202
Chain A, Casein kinase II subunit alpha0202
Chain A, Casein Kinase Ii Subunit Alpha0202
BRCA1110011
Neuraminidase 019019
pyruvate kinase210021
Aldo-keto reductase family 1 member B10011013
Poly [ADP-ribose] polymerase tankyrase-10202
Lysozyme C-10202
Glucocorticoid receptor146768
Myeloperoxidase015015
Beta-glucuronidase0303
Seed linoleate 13S-lipoxygenase-1011019
Sialidase0808
Cystic fibrosis transmembrane conductance regulator0257
17-beta-hydroxysteroid dehydrogenase type 10809
Urease subunit alpha0808
Aldo-keto reductase family 1 member B1026028
G2/mitotic-specific cyclin-B0909
Mucin-10101
Glycogen synthase kinase-3 beta0909
Proteasome subunit beta type-5015017
Testosterone 17-beta-dehydrogenase 30404
17-beta-hydroxysteroid dehydrogenase type 20909
Acetylcholinesterase0305
Peroxisome proliferator-activated receptor gamma011011
Homeobox protein Nkx-2.5 0202
Estrogen receptor0011
Death-associated protein kinase 1091423
Urease subunit beta0808
Lactoperoxidase0204
MO15-related protein kinase Pfmrk 0505
Cyclin homolog0606
Transcription factor GATA-4 0202
Cyclin-dependent kinase 5 activator 1010010
Substance-K receptor012012
Integrase 020020
Casein kinase II subunit alpha 3011011
Inositol polyphosphate multikinase0505
Enoyl-acyl-carrier protein reductase 011011
NACHT, LRR and PYD domains-containing protein 3 0404
Myocilin0011
Cyclin-dependent kinase 10909
Prenyltransferase homolog0004
Poly [ADP-ribose] polymerase tankyrase-20325
MAP kinase-interacting serine/threonine-protein kinase 2051520
Carboxylic ester hydrolase 0405
NADPH oxidase 40505
Estrogen receptor beta0011
Inositol hexakisphosphate kinase 20505
Short transient receptor potential channel 50505
Sialidase-2011011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase9009
1-phosphatidylinositol 3-phosphate 5-kinase0112
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)0101
Coagulation factor X0101
Collagenase 30707
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0022
Chain A, SERUM ALBUMIN0022
caspase-1 isoform alpha precursor170017
Fatty-acid amide hydrolase 10606
Calmodulin 0146
Lanosterol 14-alpha demethylase019221
Cytosolic phospholipase A2 gamma0202
Transient receptor potential cation channel subfamily V member 20527
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Nitric oxide synthase, endothelial0103
Nitric oxide synthase, inducible0809
Cationic amino acid transporter 30202
Integrin beta-10404
Integrin alpha-V 0202
Integrin alpha-50202
Integrin beta-50101
5-hydroxytryptamine receptor 3E0606
mu-type opioid receptor isoform MOR-10033
5-hydroxytryptamine receptor 2A0033
Solute carrier family 22 member 2019026
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 3B0606
D020122
Alpha-1D adrenergic receptor041850
D(4) dopamine receptor015015
5-hydroxytryptamine receptor 7013114
5-hydroxytryptamine receptor 3A09110
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0707
5-hydroxytryptamine receptor 3D0606
Multidrug and toxin extrusion protein 2013013
5-hydroxytryptamine receptor 3C0606
Multidrug and toxin extrusion protein 1031031
Chain A, Hyaluronidase, phage associated0101
Pancreatic alpha-amylase0202
Albumin0405
Urease0506
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase010010
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20135
Egl nine homolog 104611
Prolyl hydroxylase EGLN30034
Hypoxia-inducible factor 1-alpha inhibitor0304
Solute carrier family 23 member 10101
Neutral amino acid transporter A0505
Neutral amino acid transporter B(0)0505
Carbonic anhydrase-like protein, putative0009
Amino acid transporter0505
Metabotropic glutamate receptor 60112
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0202
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Glutamate receptor ionotropic, NMDA 2D016226
Glutamate receptor ionotropic, NMDA 3B016226
Glutamate receptor ionotropic, NMDA 3A016226
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0022
ras protein, partial0022
Rac1 protein0022
cell division cycle 42 (GTP binding protein, 25kDa), partial0022
Prostaglandin-H2 D-isomerase0202
Fatty acid-binding protein, liver013215
Glutathione hydrolase 1 proenzyme0101
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0202
Ras-related protein Rab-2A0022
Rho-associated protein kinase 20303
Sigma non-opioid intracellular receptor 1015318
Polycomb protein EED0213
HLA class I histocompatibility antigen, A alpha chain 0134
Somatostatin receptor type 20202
Somatostatin receptor type 40202
Somatostatin receptor type 30202
Somatostatin receptor type 50202
Sigma intracellular receptor 20808
Heparanase0033
Beta-1 adrenergic receptor 02711
Solute carrier organic anion transporter family member 2B1 010014
3-hydroxy-3-methylglutaryl-coenzyme A reductase0707
Insulin receptor 0404
Dipeptidyl peptidase 40202
Endothelin receptor type B85114
Endothelin receptor type B0505
Endothelin-1 receptor84113
Endothelin receptor type B0101
Atrial natriuretic peptide receptor 10112
Atrial natriuretic peptide receptor 1 0011
cystic fibrosis transmembrane conductance regulator0404
short transient receptor potential channel 6 isoform 10022
Muscarinic acetylcholine receptor M10125
Muscarinic acetylcholine receptor M40416
Muscarinic acetylcholine receptor0326
Sterol O-acyltransferase 20101
Sterol O-acyltransferase 10101
Sterol O-acyltransferase 10303
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Leukotriene C4 synthase001212
tyrosine-protein kinase Yes250025
Cell division cycle 7-related protein kinase011617
Serine/threonine-protein kinase 25011415
Serine/threonine-protein kinase RIO3001414
Inhibitor of nuclear factor kappa-B kinase subunit beta041217
Peripheral plasma membrane protein CASK001212
Serine/threonine-protein kinase DCLK1011415
Inhibitor of nuclear factor kappa-B kinase subunit alpha021214
Muscle, skeletal receptor tyrosine-protein kinase011415
3-phosphoinositide-dependent protein kinase 1031518
Mitogen-activated protein kinase kinase kinase 13001212
Death-associated protein kinase 3011516
NUAK family SNF1-like kinase 1041418
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma001212
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma001212
Serine/threonine-protein kinase PAK 3011415
Cyclin-dependent kinase-like 5002323
Serine/threonine-protein kinase 17B021416
Cyclin-dependent kinase 14021417
Serine/threonine-protein kinase OSR1001212
Serine/threonine-protein kinase Chk2031215
RAF proto-oncogene serine/threonine-protein kinase0121529
Proto-oncogene tyrosine-protein kinase ROS021416
Tyrosine-protein kinase Fgr022325
Wee1-like protein kinase 2001212
Uncharacterized serine/threonine-protein kinase SBK3001212
Mast/stem cell growth factor receptor Kit0141529
Insulin receptor-related protein011415
Platelet-derived growth factor receptor alpha0101525
Vascular endothelial growth factor receptor 1 081422
Interferon-induced, double-stranded RNA-activated protein kinase021416
Serine/threonine-protein kinase MAK011213
Cyclin-dependent kinase 11B011416
Receptor tyrosine-protein kinase erbB-3031215
Protein kinase C eta type061622
Activin receptor type-2A001414
Ephrin type-A receptor 3011516
Ephrin type-A receptor 8011415
Leukocyte tyrosine kinase receptor011415
UMP-CMP kinase 001819
Phosphatidylethanolamine-binding protein 1002323
Tyrosine-protein kinase receptor UFO041418
Mitogen-activated protein kinase 4001414
S-adenosylmethionine synthase isoform type-2002828
G protein-coupled receptor kinase 4011213
Myosin-10002020
Tyrosine-protein kinase receptor Tie-1001414
Vascular endothelial growth factor receptor 30101424
Vascular endothelial growth factor receptor 20251541
Serine/threonine-protein kinase receptor R3011819
Electron transfer flavoprotein subunit beta002222
Megakaryocyte-associated tyrosine-protein kinase011213
Tyrosine-protein kinase TXK031518
Tyrosine-protein kinase ZAP-70041418
Dual specificity mitogen-activated protein kinase kinase 4022325
Cyclin-dependent kinase 8041419
Choline-phosphate cytidylyltransferase A001616
Cysteine--tRNA ligase, cytoplasmic002323
Tyrosine-protein kinase Blk041519
Cytoplasmic tyrosine-protein kinase BMX051520
cAMP-dependent protein kinase catalytic subunit PRKX011516
Serine/threonine-protein kinase Nek4011213
Ephrin type-B receptor 1011415
Hormonally up-regulated neu tumor-associated kinase001212
Serine/threonine-protein kinase SIK1011415
Receptor-interacting serine/threonine-protein kinase 4001212
Cell division control protein 2 homolog001212
Calcium-dependent protein kinase 1001212
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta001414
SRSF protein kinase 2011415
Mitogen-activated protein kinase kinase kinase 9021416
Serine/threonine-protein kinase PknB001212
Cyclin-dependent kinase-like 1001212
Protein kinase C epsilon type091625
Mitogen-activated protein kinase kinase kinase 10021416
Protein kinase C zeta type051621
Tyrosine-protein kinase receptor TYRO3011415
Cyclin-dependent kinase 18021821
Tyrosine-protein kinase ITK/TSK061622
Myotonin-protein kinase021416
Mitogen-activated protein kinase kinase kinase 12011213
Serine/threonine-protein kinase PAK 1031417
Serine/threonine-protein kinase PAK 2023032
cGMP-dependent protein kinase 2011415
Serine/threonine-protein kinase PRP4 homolog001212
Receptor-interacting serine/threonine-protein kinase 1031518
Calcium/calmodulin-dependent protein kinase type II subunit beta031417
Calcium/calmodulin-dependent protein kinase type 1011516
Peroxisomal acyl-coenzyme A oxidase 1002323
Serine/threonine-protein kinase D1041519
Receptor tyrosine-protein kinase erbB-4061319
Ribosomal protein S6 kinase alpha-2011516
Rhodopsin kinase GRK1021214
NT-3 growth factor receptor011415
BDNF/NT-3 growth factors receptor011516
Mitogen-activated protein kinase 6001414
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform011415
Serine/threonine-protein kinase SBK1011213
Mitogen-activated protein kinase kinase kinase 19011213
Serine/threonine-protein kinase TNNI3K011415
Serine/threonine-protein kinase Nek5011415
Dual serine/threonine and tyrosine protein kinase021214
Mitogen-activated protein kinase kinase kinase 15001212
Myosin-14002727
Serine/threonine-protein kinase tousled-like 2011415
Serine/threonine-protein kinase 32C011415
Serine/threonine-protein kinase VRK2011213
Myosin light chain kinase family member 4011415
Homeodomain-interacting protein kinase 1031215
Calcium/calmodulin-dependent protein kinase type 1D011516
Cyclin-dependent kinase-like 3011213
Serine/threonine-protein kinase BRSK2011415
Serine/threonine-protein kinase NIM1011213
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B001010
Serine/threonine-protein kinase ULK2011213
Serine/threonine-protein kinase DCLK2011415
Calcium/calmodulin-dependent protein kinase kinase 1011415
Casein kinase I isoform alpha-like011415
Homeodomain-interacting protein kinase 4021214
Myosin-IIIa011415
Ankyrin repeat and protein kinase domain-containing protein 1001414
Serine/threonine-protein kinase Nek11011213
Serine/threonine-protein kinase BRSK1011415
Serine/threonine-protein kinase 35001212
Serine/threonine-protein kinase Nek7002222
Rhodopsin kinase GRK7011213
Serine/threonine-protein kinase 32A001212
Myosin-IIIb011415
Dual specificity tyrosine-phosphorylation-regulated kinase 2021214
Cyclin-dependent kinase-like 2001212
Serine/threonine-protein kinase Sgk3011213
Atypical kinase COQ8B, mitochondrial001414
Cyclin-dependent kinase 15011214
SRSF protein kinase 1011415
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha001414
Serine/threonine-protein kinase RIO1001414
MAP kinase-interacting serine/threonine-protein kinase 1041418
Serine/threonine-protein kinase RIO2001212
Cyclin-dependent kinase 19021417
Transient receptor potential cation channel subfamily M member 6001212
Testis-specific serine/threonine-protein kinase 1011415
Serine/threonine-protein kinase 33011415
Serine/threonine-protein kinase DCLK3001414
Myosin light chain kinase 2, skeletal/cardiac muscle011415
Homeodomain-interacting protein kinase 2021214
Tyrosine-protein kinase Srms011415
Homeodomain-interacting protein kinase 3021214
Dual specificity protein kinase CLK4013233
Serine/threonine-protein kinase Nek6021416
Serine/threonine-protein kinase PAK 6022830
SNF-related serine/threonine-protein kinase011213
Serine/threonine-protein kinase LATS2011415
Serine/threonine-protein kinase 36011516
Serine/threonine-protein kinase 32B011415
Serine/threonine-protein kinase MARK1011415
Serine/threonine-protein kinase PAK 5021416
eIF-2-alpha kinase GCN2001414
Serine/threonine-protein kinase 17A011516
STE20/SPS1-related proline-alanine-rich protein kinase011213
Ephrin type-A receptor 6011415
Death-associated protein kinase 2011516
TRAF2 and NCK-interacting protein kinase023335
Serine/threonine-protein kinase tousled-like 1011415
ALK tyrosine kinase receptor041721
SRSF protein kinase 3011213
Cyclin-dependent kinase 11A001414
Aurora kinase C011516
Calcium/calmodulin-dependent protein kinase type II subunit alpha021416
Microtubule-associated serine/threonine-protein kinase 1001212
Thyroid hormone receptor-associated protein 3002222
Dual specificity tyrosine-phosphorylation-regulated kinase 1B022224
Protein-arginine deiminase type-4013013
Skn7p0003
Janus kinase 2 (a protein tyrosine kinase)0202
Orotidine 5'-phosphate decarboxylase0202
Orotidine 5'-phosphate decarboxylase0101
Chain A, Diaminopimelate decarboxylase0101
Chain B, Diaminopimelate decarboxylase0101
Gamma-aminobutyric acid type B receptor subunit 20224
Gamma-aminobutyric acid type B receptor subunit 20303
Gamma-aminobutyric acid type B receptor subunit 10224
Gamma-aminobutyric acid type B receptor subunit 10202
Lysine-specific histone demethylase 1A014015
Canalicular multispecific organic anion transporter 10709
Hypoxia-inducible factor 1-alpha09111
Endothelial PAS domain-containing protein 10416
Membrane-associated progesterone receptor component 1001919
MAP kinase-activated protein kinase 3011112
Uncharacterized aarF domain-containing protein kinase 5001717
Isoleucine--tRNA ligase, mitochondrial001717
Nuclear factor NF-kappa-B p100 subunit 0808
Transcription factor p65012012
NACHT, LRR and PYD domains-containing protein 3 0606
Nrf2150015
transient receptor potential cation channel subfamily V member 15005
calpain II, partial0202
PINK1140014
shiga toxin 1 variant A subunit2002
shiga toxin 1 B subunit2002
heat shock protein HSP 90-alpha isoform 207021
heat shock protein 90, putative00014
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
Endolysin0033
Chain A, GTPase KRas, isoform 2B0011
Chain A, GTPase KRas, isoform 2B0011
GTPase KRas0213
Membrane primary amine oxidase0101
Glutaminyl-peptide cyclotransferase0505
Aryl hydrocarbon receptor0123
Chain A, Oxygen-insensitive Nad(p)h Nitroreductase0101
Chain B, Oxygen-insensitive Nad(p)h Nitroreductase0101
D-amino-acid oxidase0112
D-amino-acid oxidase0314
Metabotropic glutamate receptor 50011
Alpha-glucosidase MAL120303
Monocarboxylate transporter 10103
D-aspartate oxidase0202
Serine racemase0202
Telomerase reverse transcriptase0606
Neuraminidase0404
Neuraminidase0606
Cholinesterase021021
Aldo-keto reductase family 1 member C3014014
Aldo-keto reductase family 1 member C2 010010
Lysine-specific demethylase 4E0909
galactokinase5005
Cocaine esterase0505
Tyrosyl-DNA phosphodiesterase 20202
NAD0307
NADPH--cytochrome P450 reductase0101
Liver carboxylesterase 108015
Mucosa-associated lymphoid tissue lymphoma translocation protein 10101
phosphoglycerate kinase140014
Chain A, D-MALTODEXTRIN BINDING PROTEIN0011
Chain A, Limit Dextrinase0011
Chain A, Solute-binding protein0011
Chain A, Solute-binding protein0011
Chain B, SusD0011
Chain A, SusD0011
Chain A, SusD0011
Chain A, Alpha-hemolysin0011
Chain B, Alpha-hemolysin0011
Chain C, Alpha-hemolysin0011
Chain D, Alpha-hemolysin0011
Chain E, Alpha-hemolysin0011
Chain F, Alpha-hemolysin0011
Chain G, Alpha-hemolysin0011
Chain A, Betaine ABC transporter permease and substrate binding protein0011
Chain A, Osmoprotection protein (ProX)0011
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
galanin receptor type 30101
Glycine receptor subunit alpha-1044044
Glycine receptor subunit beta044044
Glycine receptor subunit alpha-2044044
Glycine receptor subunit alpha-3044044
Glucocorticoid receptor0528
Ubiquitin-like modifier activating enzyme 20202
SUMO1 activating enzyme subunit 10202
SUMO-conjugating enzyme UBC90202
Pancreatic alpha-amylase0507
Albumin0122748
DNA polymerase beta0505
DNA polymerase beta0303
Zinc finger protein GLI10202
5'-nucleotidase0101
Env polyprotein 0033
Phosphodiesterase isozyme 4 0101
Transmembrane prolyl 4-hydroxylase0033
Non-structural protein 1 0101
Cytochrome P450 26A10426
Cytochrome P450 26B10303
Caspase-7170017
L-selectin0202
P-selectin0202
E-selectin0202
P-selectin glycoprotein ligand 10101
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
nonstructural protein 10202
green fluorescent protein, partial0101
insulin-degrading enzyme isoform 10011
Receptor-type tyrosine-protein phosphatase beta0002
Beta-1 adrenergic receptor0415
Genome polyprotein 0101
Non-structural protein 4A 0101
Nonstructural protein 5A 0112
Beta-lactamase0204
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110102
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70102
26S proteasome non-ATPase regulatory subunit 30101
Chymotrypsinogen A010010
Cathepsin G0303
Lysosomal protective protein0203
Chymotrypsinogen B0707
26S proteasome regulatory subunit 6A0101
Proteasome subunit beta type-10204
Chymase0101
Proteasome subunit alpha type-10102
Proteasome subunit alpha type-20102
Proteasome subunit alpha type-30102
Proteasome subunit alpha type-40102
Proteasome subunit beta type-80203
Proteasome subunit beta type-80101
Proteasome subunit beta type-90102
Proteasome subunit alpha type-50102
Proteasome subunit beta type-40102
Proteasome subunit beta type-60102
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100102
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30102
Proteasome subunit beta type-20204
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60113
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
26S proteasome non-ATPase regulatory subunit 20101
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
ATP-dependent Clp protease proteolytic subunit0112
Proteasome subunit alpha-type 80102
Proteasome subunit beta type-70102
26S proteasome non-ATPase regulatory subunit 10101
26S proteasome non-ATPase regulatory subunit 130101
B2 bradykinin receptor0101
B1 bradykinin receptor0101
Olfactory receptor 51E20167
Genome polyprotein 07310
D(3) dopamine receptor019019
D(1B) dopamine receptor013013
Nuclear hormone receptor family member daf-120112
oxysterols receptor LXR-beta isoform 10112
Thymidine phosphorylase0015
Thymidylate kinase0202
Thymidine kinase0004
Thymidylate kinase0303
vasopressin V1b receptor3003
cAMP-dependent protein kinase type I-alpha regulatory subunit0011
cAMP-dependent protein kinase type II-beta regulatory subunit0011
cAMP-dependent protein kinase catalytic subunit beta isoform 10011
relaxin receptor 1 isoform 18008
relaxin receptor 2 isoform 13003
cAMP-dependent protein kinase catalytic subunit beta isoform 30011
leucine aminopeptidase0101
M17 leucyl aminopeptidase0202
M18 aspartyl aminopeptidase0303
M1-family alanyl aminopeptidase0202
M17 leucyl aminopeptidase0101
Solute carrier family 12 member 20101
Acetylcholine receptor subunit alpha0527
Acetylcholine receptor subunit gamma0527
Acetylcholine receptor subunit beta0527
Neuronal acetylcholine receptor subunit beta-20528
Neuronal acetylcholine receptor subunit beta-40528
Neuronal acetylcholine receptor subunit alpha-30527
Neuronal acetylcholine receptor subunit alpha-70538
Neuronal acetylcholine receptor subunit alpha-40528
Acetylcholine receptor subunit delta0527
Chain A, Nitrile Hydratase alpha subunit0101
Chain B, Nitrile Hydratase beta subunit0101
Methyl-accepting chemotaxis protein NahY0033
C-C chemokine receptor type 10213
C-C chemokine receptor type 10112
C-C motif chemokine receptor 1 0101
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0022
Chain A, glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Chitinase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Vasopressin V2 receptor0002
Adenylate cyclase type 10114
Chitotriosidase-10415
Adenosine receptor A2b0114
Palmitoleoyl-protein carboxylesterase NOTUM0235
Endochitinase B10415
electroneutral potassium-chloride cotransporter KCC20011
TSHR protein5005
LacZ protein (plasmid)0022
XBP10202
type-1 angiotensin II receptor0202
apelin receptor0303
DNA damage-inducible transcript 3 protein0202
Vitamin D3 receptor05716
Chain A, Vitamin D Nuclear Receptor0011
Vitamin D3 receptor0011
Vitamin D-binding protein0011
Vitamin D3 receptor0113
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0314
Vitamin D3 receptor0112
Transporter0505
Vitamin D3 receptor A0022
Serine protease hepsin0404
Furin0202
Hepatocyte growth factor activator0101
Transmembrane protease serine 60202
DNA topoisomerase 0101
putative alpha-glucosidase1001
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
DNA ligase0202
Heterogeneous nuclear ribonucleoprotein A10022
Type-2 restriction enzyme BamHI0101
Somatostatin receptor type 10101
Type-2 restriction enzyme HindIII0101
Ribonuclease pancreatic0101
DNA topoisomerase 10102
DNA topoisomerase 10101
DNA topoisomerase type IB small subunit 0011
Leukotriene B4 receptor 216210
Cruzipain010010
NEDD8-activating enzyme E1 regulatory subunit0123
NEDD8-activating enzyme E1 catalytic subunit0022
DNA polymerase kappa0101
DNA polymerase iota0101
DNA polymerase eta0101
Cytochrome P450 2C11 0303
Steroid 17-alpha-hydroxylase/17,20 lyase 0303
Fatty acid-binding protein, liver0202
Cytochrome P450 3A50719
Cannabinoid receptor 1010214
Cytochrome P450 3A70202
Cannabinoid receptor 2 06210
N-acylethanolamine-hydrolyzing acid amidase0202
Heat sensitive channel TRPV30123
Transient receptor potential cation channel subfamily M member 80325
Transient receptor potential cation channel subfamily V member 40224
G-protein coupled receptor 550123
Diacylglycerol lipase-alpha0101
Protein phosphatase 1B0101
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit0101
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B 0101
NADH-ubiquinone oxidoreductase chain 10101
Corticotropin-releasing factor receptor 20101
Mu-type opioid receptor09317
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
Leukotriene A-4 hydrolase010213
EEF1AKMT4-ECE2 readthrough transcript protein0101
Leukotriene A-4 hydrolase0101
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0404
Angiotensin-converting enzyme0909
Beta-lactamase TEM0609
Beta-lactamase 0305
Beta-lactamase 0303
Major prion protein0088
Sodium channel protein type 1 subunit alpha0505
Sodium channel protein type 2 subunit alpha0606
Sodium channel protein type 3 subunit alpha0404
Frizzled-80011
P2X purinoceptor 40202
Lactoperoxidase0202
Chain A, serum paraoxonase0101
Glutathione reductase, mitochondrial014017
Glutathione reductase0303
Solute carrier family 22 member 50001
Solute carrier family 22 member 50102
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Farnesyl pyrophosphate synthase0404
Pancreatic triacylglycerol lipase0101
Chain A, Protein kinase CK2, alpha Subunit0101
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT0101
Chain A, Protein Kinase Ck2, Alpha Subunit0101
Serine/threonine-protein kinase Sgk10303
Casein kinase II subunit alpha 0101
Casein kinase II subunit beta0101
Cyclin-A109110
Arginase 0404
Pancreatic triacylglycerol lipase0808
Sucrase-isomaltase, intestinal0404
Dihydroorotate dehydrogenase 0707
Chain A, Neutrophil gelatinase-associated lipocalin0011
3-dehydroquinate synthase0102
Potassium-transporting ATPase subunit beta0304
Potassium-transporting ATPase alpha chain 10304
Autoinducer 2-binding periplasmic protein LuxP0404
E3 ubiquitin-protein ligase Mdm20303
Arginase-10101
Solute carrier family 22 member 706012
Solute carrier family 22 member 11010017
Solute carrier family 22 member 8012015
Solute carrier family 22 member 706010
Beta-lactamase 0205
Beta-lactamase 0204
Metallo-beta-lactamase VIM-19 0005
Beta-lactamase 0105
Beta-lactamase 0003
Beta-lactamase 0105
Metallo-beta-lactamase VIM-20005
BlaVIM-1 0005
Beta-lactamase 0003
Beta-lactamase 0105
Solute carrier family 22 member 809012
L-ornithine N(5)-monooxygenase0112
Ubiquitin carboxyl-terminal hydrolase 20202
Ubiquitin carboxyl-terminal hydrolase isozyme L10202
Ubiquitin carboxyl-terminal hydrolase isozyme L30202
Tyrosine-protein phosphatase non-receptor type 20404
Receptor-type tyrosine-protein phosphatase epsilon0303
Tyrosine-protein phosphatase non-receptor type 60404
Tyrosine-protein phosphatase non-receptor type 70202
Tryptophan 2,3-dioxygenase0506
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN0101
Heat shock factor protein 10314
Tyrosine-protein phosphatase non-receptor type 110305
Regulator of G-protein signaling 170202
Ubiquitin carboxyl-terminal hydrolase 150101
Ubiquitin carboxyl-terminal hydrolase isozyme L50101
Chain A, Endoglucanase B0101
Chain A, cellulase0022
Chain A, cellulase0022
Chain A, Cellulose 1,4-beta-cellobiosidase0011
Beta-lactamase 0002
Beta-lactamase0002
Beta-lactamase0509
Beta-lactamase OXA-100002
Beta-lactamase0002
Beta-lactamase0103
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase IMP-1 0003
Beta-lactamase 0003
Trypanothione reductase015017
Caspase-20022
cGMP-specific 3',5'-cyclic phosphodiesterase0101
FAD-linked sulfhydryl oxidase ALR0004
Dihydroxyacetone phosphate acyltransferase0002
30S ribosomal protein S60629
30S ribosomal protein S70629
50S ribosomal protein L150629
50S ribosomal protein L100629
50S ribosomal protein L110629
50S ribosomal protein L7/L120629
50S ribosomal protein L190629
50S ribosomal protein L10629
50S ribosomal protein L200629
50S ribosomal protein L270629
50S ribosomal protein L280629
50S ribosomal protein L290629
50S ribosomal protein L310629
50S ribosomal protein L31 type B0629
50S ribosomal protein L320629
50S ribosomal protein L330629
50S ribosomal protein L340629
50S ribosomal protein L350629
50S ribosomal protein L360629
30S ribosomal protein S100629
30S ribosomal protein S110629
30S ribosomal protein S120629
30S ribosomal protein S130629
30S ribosomal protein S160629
30S ribosomal protein S180629
30S ribosomal protein S190629
30S ribosomal protein S200629
30S ribosomal protein S20629
30S ribosomal protein S30629
30S ribosomal protein S40629
30S ribosomal protein S50629
30S ribosomal protein S80629
30S ribosomal protein S90629
50S ribosomal protein L130629
50S ribosomal protein L140629
50S ribosomal protein L160629
50S ribosomal protein L230629
30S ribosomal protein S150629
50S ribosomal protein L170629
50S ribosomal protein L210629
50S ribosomal protein L300629
50S ribosomal protein L60629
30S ribosomal protein S140629
30S ribosomal protein S170629
30S ribosomal protein S10629
50S ribosomal protein L180629
50S ribosomal protein L20629
50S ribosomal protein L30629
50S ribosomal protein L240629
50S ribosomal protein L40629
50S ribosomal protein L220629
50S ribosomal protein L50629
30S ribosomal protein S210629
50S ribosomal protein L250629
50S ribosomal protein L36 20629
Methionine--tRNA ligase, mitochondrial0011
Coagulation factor XII0505
Liver carboxylesterase 10202
Gamma-aminobutyric acid receptor subunit alpha-10406
Gamma-aminobutyric acid receptor subunit beta-10406
Gamma-aminobutyric acid receptor subunit alpha-20406
Gamma-aminobutyric acid receptor subunit alpha-30406
Gamma-aminobutyric acid receptor subunit alpha-40406
Gamma-aminobutyric acid receptor subunit gamma-20406
Cholecystokinin receptor type A1405
Gastrin/cholecystokinin type B receptor1315
calcineurin A1, putative0033
hepatocyte nuclear factor 4-alpha isoform 20303
perilipin-50707
perilipin-10707
protein AF-9 isoform a0003
melanocortin receptor 40213
CAAX prenyl protease0002
bcl-2-related protein A10404
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0707
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0005
Solute carrier family 22 member 3012013
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Spermine oxidase0101
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1012113
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0606
glucose-6-phosphate 1-dehydrogenase isoform b0606
Riboflavin-binding protein0235
Histidine-rich protein PFHRP-II0607
Spike glycoprotein0325
DNA ligase 10101
Calcium-dependent protein kinase 10112
DNA ligase A0101
Phosphoethanolamine N-methyltransferase0202
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
MBT domain-containing protein 10202
Lethal(3)malignant brain tumor-like protein 40202
Lethal(3)malignant brain tumor-like protein 30202
Chloroquine resistance transporter0505
Lethal(3)malignant brain tumor-like protein 10202
NADPH oxidase 10202
Snq2p0006
Adenylate cyclase type 1 0404
Glutamate receptor ionotropic, NMDA 2D0516
Glutamate receptor ionotropic, NMDA 3B0516
Major prion protein0112
Cys-loop ligand-gated ion channel0101
Sphingomyelin phosphodiesterase0202
D(2) dopamine receptor0808
Adenylate cyclase type 30404
Adenylate cyclase type 20415
Adenylate cyclase type 40404
Pleiotropic ABC efflux transporter of multiple drugs06012
Adenylate cyclase type 80404
Gastrin/cholecystokinin type B receptor0505
Aldehyde oxidase 10303
Adenylate cyclase type 60404
Adenylate cyclase type 50505
Glutamate receptor ionotropic, NMDA 10718
Aldehyde oxidase0808
Glutamate receptor ionotropic, NMDA 2A0718
Glutamate receptor ionotropic, NMDA 2B0729
Glutamate receptor ionotropic, NMDA 2C0516
Adenylyl cyclase 7 0404
Glutamate receptor ionotropic, NMDA 3A0516
D0505
LAP40033
RPL19A0022
Glycoprotein hormones alpha chain6006
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70004
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10405
Solute carrier family 22 member 20303
Neuronal acetylcholine receptor subunit alpha-307311
Neuronal acetylcholine receptor subunit alpha-20427
Neuronal acetylcholine receptor subunit beta-30337
Neuronal acetylcholine receptor subunit beta-407311
Neuronal acetylcholine receptor subunit alpha-50326
Sodium- and chloride-dependent creatine transporter 10101
Neuronal acetylcholine receptor subunit alpha-60438
Neuronal acetylcholine receptor subunit alpha-90326
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100326
Chain A, Glycogen phosphorylase, muscle form0101
Chain A, Glycogen phosphorylase, muscle form0101
nuclear receptor subfamily 0 group B member 10707
steroidogenic factor 10707
Aldo-keto reductase family 1 member B10808
Carbonyl reductase [NADPH] 10608
3-oxoacyl-acyl-carrier protein reductase 0808
Isocitrate dehydrogenase [NADP] cytoplasmic0101
Lysine-specific demethylase 4B0101
Deoxyhypusine hydroxylase0101
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Dipeptidase 10101
Beta-3 adrenergic receptor0628
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0202
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0202
Phosphodiesterase 0303
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0404
Potassium-transporting ATPase alpha chain 10202
Potassium-transporting ATPase subunit beta0202
Solute carrier family 22 member 40101
Cell division protein FtsZ0103
DNA gyrase subunit B0202
DNA gyrase subunit A0202
DNA gyrase subunit B0507
DNA gyrase subunit A07011
DNA gyrase subunit B07111
DNA topoisomerase 4 subunit A0202
DNA topoisomerase 4 subunit B0203
DNA topoisomerase 4 subunit A0203
DNA gyrase subunit A0507
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0708
DNA gyrase subunit A0708
Enoyl-[acyl-carrier-protein] reductase [NADH]0408
DNA topoisomerase 4 subunit A0202
DNA topoisomerase 4 subunit B0202
Sodium-dependent noradrenaline transporter0505
Tryptophan 5-hydroxylase 10202
Sodium-dependent serotonin transporter0505
Sodium-dependent dopamine transporter0606
Transporter020122
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Beta-lactamase0202
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0102
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0606
Alpha-ketoglutarate-dependent dioxygenase FTO0404
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10608
General amino-acid permease GAP10001
mu opioid receptor, partial0011
90-kda heat shock protein beta HSP90 beta, partial0707
MEP20022
delta-type opioid receptor0112
kappa-type opioid receptor isoform 10101
Catechol O-methyltransferase0213
Beta-galactosidase0011
Type IV secretion-like conjugative transfer relaxase protein TraI 0202
Macrophage metalloelastase0404
mitogen-activated protein kinase kinase kinase kinase 2 isoform 10011
mitogen-activated protein kinase kinase kinase 3 isoform 10011
C-terminal-binding protein 15005
Peroxisome proliferator-activated receptor alpha0246
Alpha-1B adrenergic receptor 0011
Alpha-1A adrenergic receptor0415
Alpha-2B adrenergic receptor0102
Alpha-2C adrenergic receptor0102
Alpha-2A adrenergic receptor0102
Alpha-2A adrenergic receptor0101
Nischarin0303
Nischarin0202
beta-2 adrenergic receptor100111
Intermediate conductance calcium-activated potassium channel protein 40101
Heme oxygenase 1 0707
Epoxide hydrolase 10004
Heme oxygenase 20606
C-X-C chemokine receptor type 10404
Indoleamine 2,3-dioxygenase 10808
Vasopressin V2 receptor0202
Malate dehydrogenase, cytoplasmic0606
Transitional endoplasmic reticulum ATPase0202
Cytochrome P450 1440044
Steroid C26-monooxygenase0044
Cytochrome P450 1300011
Cytochrome P450 1300011
Steroid C26-monooxygenase0044
Mycocyclosin synthase0033
Lanosterol 14-alpha demethylase0044
Nuclear receptor subfamily 1 group I member 3 0303
Sterol 14-alpha demethylase0022
Indoleamine 2,3-dioxygenase 20707
14-alpha sterol demethylase 0022
Cysteinyl leukotriene receptor 1010414
5-hydroxytryptamine receptor 3A0404
5-hydroxytryptamine receptor 2C 0404
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 5A0202
D(2) dopamine receptor0202
D(3) dopamine receptor0202
D(2) dopamine receptor0303
5-hydroxytryptamine receptor 2B0202
Cholecystokinin receptor type A0404
5-hydroxytryptamine receptor 1A0202
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Fatty acid-binding protein, heart0303
Muscarinic acetylcholine receptor M20112
Lysosomal Pro-X carboxypeptidase0202
Cytochrome P450 2D10505
Cytochrome P450 2D260606
Cytochrome P450 2D30606
Kappa-type opioid receptor07313
Cytochrome P450 2D40606
Mas-related G-protein coupled receptor member X20088
Histone acetyltransferase KAT2B0202
Histone acetyltransferase KAT50202
N-alpha-acetyltransferase 500011
Vesicular acetylcholine transporter0101
Tubulin polymerization-promoting protein0011
CREB-binding protein3306
Adenylate cyclase type 80011
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20088
Solute carrier family 22 member 30202
Exportin-10101
NAD-dependent histone deacetylase SIR20204
Acetylcholinesterase0707
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0303
Quinone oxidoreductase0007
Sorbitol dehydrogenase0303
Induced myeloid leukemia cell differentiation protein Mcl-10707
Zn finger protein 0101
Substance-P receptor0213
Neuromedin-K receptor0022
Neuromedin-K receptor0415
Neuromedin-K receptor0112
Substance-K receptor0202
Sodium- and chloride-dependent creatine transporter 10101
Alkaline phosphatase, germ cell type0101
G protein-coupled receptor GPR350022
G-protein coupled receptor 350011
G-protein coupled receptor 3507714
Papain0101
Receptor-type tyrosine-protein phosphatase C0202
Receptor-type tyrosine-protein phosphatase F0303
Tyrosine-protein phosphatase non-receptor type 90101
toll-like receptor 90101
TPA: protein transporter TIM100404
Phospholipase A20303
Neuronal proto-oncogene tyrosine-protein kinase Src 0101
Glutathione S-transferase P0202
Microtubule-associated protein tau0618
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Aminopeptidase N0606
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20202
Voltage-dependent L-type calcium channel subunit alpha-1D0404
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Nuclear factor erythroid 2-related factor 201610
Thioredoxin reductase 1, cytoplasmic0708
Thioredoxin reductase 30404
Sortase A0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30202
Thioredoxin reductase 2, mitochondrial0404
CDGSH iron-sulfur domain-containing protein 1018018
Lymphocyte antigen 960022
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10606
Chain A, Homo sapiens cyclin-dependent kinase 20101
Chain C, Cell division protein kinase 20101
Chain C, Cell division protein kinase 20101
Glycogen synthase kinase-3 beta 0202
[Tau protein] kinase 0202
Dual specificity protein kinase CLK20101
Dual specificity protein kinase CLK30101
Dual specificity protein kinase CLK40101
Dual specificity tyrosine-phosphorylation-regulated kinase 30202
Cyclin-T10606
G1/S-specific cyclin-E20303
cGMP-dependent protein kinase 1 0101
Myosin light chain kinase, smooth muscle001010
Synapsin-10101
Dual specificity protein kinase CLK10101
G1/S-specific cyclin-D1010010
Cyclin-C0314
G1/S-specific cyclin-E10808
G1/S-specific cyclin-D30404
Cyclin-H0404
CDK-activating kinase assembly factor MAT10303
Tubulin alpha-1A chain001010
Casein kinase I isoform alpha0101
Cyclin-dependent-like kinase 50101
Cyclin-dependent kinase 1001911
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0303
Cyclin-dependent kinase 200102
Multidrug resistance-associated protein 50203
Dihydrofolate reductase0404
Bifunctional dihydrofolate reductase-thymidylate synthase0909
Dihydrofolate reductase013014
Trace amine-associated receptor 50044
transactivating tegument protein VP16 [Human herpesvirus 1]0707
COUP transcription factor 2 isoform a0101
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A07310
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40202
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
Integrin alpha-40303
Smoothened homolog0213
Sonic hedgehog protein0203
Sonic hedgehog protein0314
Smoothened homolog0538
chaperonin GroEL2002
Glycogen phosphorylase, muscle form0101
Histone-lysine N-methyltransferase SETD70606
Histone-lysine N-methyltransferase EHMT20606
Histone-lysine N-methyltransferase EHMT10404
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0505
nuclear receptor coactivator 3 isoform a0505
Thymidine kinase 2, mitochondrial0101
Thymidine kinase0203
Thymidylate synthase0406
Thymidine kinase0101
Probable deoxycytidylate deaminase0002
Cytidine deaminase0205
Enoyl-[acyl-carrier-protein] reductase [NADH] 0404
Deoxynucleoside kinase0101
neutrophil cytosol factor 10303
Solute carrier family 2, facilitated glucose transporter member 30101
Solute carrier family 2, facilitated glucose transporter member 40101
Deoxycytidine kinase0001
Alpha-tocopherol transfer protein0011
Pirin0202
Isocitrate lyase0202
RAD510101
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20102
Pantothenate synthetase0303
Growth factor receptor-bound protein 2 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0101
Regulatory-associated protein of mTOR0303
Phosphatidylinositol 3-kinase catalytic subunit type 30202
Target of rapamycin complex subunit LST80303
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0101
Chain B, Retinoid X receptor, alpha0011
Casein kinase II subunit alpha0202
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
runt-related transcription factor 1 isoform AML1b9009
core-binding factor subunit beta isoform 29009
NADH-ubiquinone oxidoreductase chain 40001
Glutamate receptor 183113
Glutamate receptor 383113
Glutamate receptor 483113
exodeoxyribonuclease V subunit RecD0404
exodeoxyribonuclease V subunit RecB0404
exodeoxyribonuclease V subunit RecC0404
DNA (cytosine-5)-methyltransferase 10404
Beta-glucuronidase0202
Beta-glucuronidase0303
Glucose-6-phosphate 1-dehydrogenase 0101
Solute carrier organic anion transporter family member 1A50005
Solute carrier organic anion transporter family member 1A20106
ATP-binding cassette sub-family C member 110002
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20104
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Ileal sodium/bile acid cotransporter0202
Thymidine kinase 2 0202
AAA family ATPase 0002
AAA family ATPase 0001
Chain A, Dutpase0011
Chain A, Dutpase0011
Chain B, Dutpase0011
Chain A, Dutpase0011
Chain B, Dutpase0011
Taste receptor type 2 member 460022
Chain A, BETA-GLUCOSIDASE0101
caspase 7, apoptosis-related cysteine peptidase0011
caspase-3 isoform a preproprotein0112
Rev0101
endoribonuclease toxin MazF0022
Female germline-specific tumor suppressor gld-10101
Monoglyceride lipase0505
Gamma-aminobutyric acid 0415
Alpha-1-acid glycoprotein 10002
Gamma-aminobutyric acid receptor subunit alpha-60415
Gamma-aminobutyric acid receptor subunit gamma-20415
Gamma-aminobutyric acid receptor subunit delta0415
Gamma-aminobutyric acid receptor subunit alpha-20415
Gamma-aminobutyric acid receptor subunit alpha-30415
Gamma-aminobutyric acid receptor subunit gamma-30415
Translocator protein0101
Translocator protein0618
Gamma-aminobutyric acid receptor subunit beta-10415
Gamma-aminobutyric acid receptor subunit alpha-10415
Gamma-aminobutyric acid receptor subunit beta-30415
Gamma-aminobutyric acid receptor subunit alpha-50415
Gamma-aminobutyric acid receptor subunit pi0415
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit alpha-40415
Gamma-aminobutyric acid receptor subunit theta0415
Gamma-aminobutyric acid receptor subunit gamma-10415
Cytochrome c oxidase subunit 20404
Interleukin-80303
Calcium/calmodulin-dependent protein kinase type II subunit alpha0202
Sodium- and chloride-dependent GABA transporter 10707
Sodium- and chloride-dependent GABA transporter 20707
Sodium- and chloride-dependent GABA transporter 30707
Prostaglandin G/H synthase 2 011014
Sodium- and chloride-dependent betaine transporter0707
Prostaglandin G/H synthase 209010
Prostaglandin G/H synthase 1 012015
UDP-glucuronosyltransferase 1A70204
UDP-glucuronosyltransferase 1A100205
NAD0101
ATP phosphoribosyltransferase0101
Proprotein convertase subtilisin/kexin type 70202
Vasopressin V1a receptor0718
UDP-glucose 4-epimerase0101
Chain A, DigA160022
Chain A, DigA160022
Sodium/potassium-transporting ATPase subunit alpha-1 0809
Sodium/potassium-transporting ATPase subunit beta-10809
Sodium/potassium-transporting ATPase subunit alpha-30506
Sodium/potassium-transporting ATPase subunit beta-20506
Sodium/potassium-transporting ATPase subunit alpha-20809
Sodium/potassium-transporting ATPase subunit alpha-10202
Potassium-transporting ATPase alpha chain 20102
Sodium/potassium-transporting ATPase subunit beta-30506
Sodium/potassium-transporting ATPase subunit gamma0506
Sodium/potassium-transporting ATPase subunit alpha-40506
Solute carrier organic anion transporter family member 4C10205
STAT3, partial0202
signal transducer and activator of transcription 1-alpha/beta isoform alpha0202
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-3 0202
Sodium/potassium-transporting ATPase subunit beta-1 0202
Sodium/potassium-transporting ATPase subunit alpha-40202
Solute carrier organic anion transporter family member 4C10002
Solute carrier organic anion transporter family member 1A40001
Dihydrofolate synthase/folylpolyglutamate synthase0101
Kelch-like ECH-associated protein 10134
Cereblon isoform 40606
Insulin-like growth factor-binding protein 50011
Glutathione S-transferase omega-10303
Thromboxane A2 receptor 0215
Prostaglandin E2 receptor EP1 subtype0336
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0224
Prostaglandin E2 receptor EP3 subtype0426
Prostaglandin E2 receptor EP2 subtype0325
Prostaglandin F2-alpha receptor0011
Prostaglandin D2 receptor0112
Solute carrier organic anion transporter family member 2A10202
prostaglandin E2 receptor EP2 subtype1002
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70001
Histamine N-methyltransferase0001
Calcium release-activated calcium channel protein 10303
Protein orai-20101
Protein orai-30101
DNA polymerase III, partial100010
LANA0002
kelch-like ECH-associated protein 10002
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
3',5'-cyclic-AMP phosphodiesterase 0606
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Exopolyphosphatase PRUNE10101
Phosphodiesterase 0303
polypyrimidine tract-binding protein 1 isoform a1001
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase0404
Carbamate kinase0101
Aldehyde dehydrogenase, mitochondrial0202
C-X-C chemokine receptor type 20303
Protein-lysine 6-oxidase0202
Gasdermin-D0101
Lysyl oxidase homolog 30202
Lysyl oxidase homolog 40202
Gasdermin-D0101
Lysyl oxidase homolog 20202
hypothetical protein CAALFM_CR05890CA0004
H3 histone acetyltransferase0004
POU domain, class 2, transcription factor 10102
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20202
Cannabinoid receptor 10505
N-arachidonyl glycine receptor0011
Lysophosphatidylserine lipase ABHD120101
Monoacylglycerol lipase ABHD60101
Cannabinoid receptor 20202
replicative DNA helicase0005
recombinase A0055
UDP-glucuronosyltransferase 2B170001
Eyes absent homolog 20202
Chain A, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, Pol Polyprotein0101
Chain B, Pol Polyprotein0101
Prothrombin 0303
Gag-Pol polyprotein0707
Gag-Pol polyprotein0808
Microsomal triglyceride transfer protein large subunit0202
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 0101
Fructose-1,6-bisphosphatase 1 0002
Reverse transcriptase 0224
Cholesterol 24-hydroxylase0011
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))0101
5-hydroxytryptamine receptor 1B0426
NS5 0033
Serine hydrolase RBBP90101
Chain A, PROTEIN KINASE CK2, ALPHA SUBUNIT0101
Chain A, Casein kinase II, alpha chain0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0011
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0011
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ0202
Protein tyrosine phosphatase type IVA 30101
Accessory gene regulator protein A0101
Genome polyprotein0101
Genome polyprotein 0606
Sodium/glucose cotransporter 10224
Sodium/glucose cotransporter 20325
Opioid receptor, delta 1b 0202
Opioid receptor homologue0202
Proenkephalin-B0011
Kappa-type opioid receptor010415
Mu-type opioid receptor0202
Histone deacetylase 80202
Histone deacetylase-like amidohydrolase0415
NAD-dependent protein deacetylase sirtuin-105110
Histone deacetylase 0202
Nuclear receptor corepressor 20505
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10011
Chain A, POLYMERASE PA0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
NAD kinase0213
Polymerase acidic protein0123
Plasminogen activator inhibitor 10303
Matrilysin0505
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0404
Alpha-amylase 1A 0404
Apoptosis regulator Bcl-20404
Glucose-6-phosphate 1-dehydrogenase0101
Fatty acid synthase0303
CPG DNA methylase0101
Phosphoglycerate mutase 10101
DNA repair protein RAD52 homolog0101
Matrix metalloproteinase-140101
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT60303
Squalene monooxygenase 0304
6-phosphogluconate dehydrogenase, decarboxylating0505
BH3-interacting domain death agonist0101
Bcl-2-like protein 10404
Alpha-(1,3)-fucosyltransferase 70303
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 10303
Bcl-2-related protein A10101
3-oxoacyl-[acyl-carrier-protein] reductase 0101
Bcl-2-like protein 20101
Bcl2-associated agonist of cell death 0101
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0606
Bcl-2-like protein 100101
Serine/threonine-protein kinase B-raf 0303
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0202
Motilin receptor0112
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0505
Flavin reductase (NADPH)0022
MPI protein0202
ERAP1 protein0001
ERAP2 protein0001
leucyl-cystinyl aminopeptidase [Mus musculus]0001
Macrophage migration inhibitory factor0909
Ghrelin O-acyltransferase0303
Hydroxycarboxylic acid receptor 20415
14 kDa phosphohistidine phosphatase0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Regulatory protein E20022
DNA topoisomerase 20002
Caspase-30404
DNA topoisomerase 2-alpha 0001
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Transient receptor potential cation channel subfamily M member 80136
Ubiquitin carboxyl-terminal hydrolase isozyme L30202
Ubiquitin carboxyl-terminal hydrolase isozyme L10202
Potassium voltage-gated channel subfamily E member 10606
Potassium voltage-gated channel subfamily KQT member 10606
Potassium voltage-gated channel subfamily D member 30404
NAD-dependent protein deacetylase sirtuin-20415
Fatty acid-binding protein, liver0112
Peroxisome proliferator-activated receptor alpha0011
Retinol-binding protein 40033
Prosaposin0011
Hyaluronidase-10202
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 10101
3-oxo-5-alpha-steroid 4-dehydrogenase 10202
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0404
3-oxo-5-alpha-steroid 4-dehydrogenase 20202
3-oxo-5-alpha-steroid 4-dehydrogenase 20404
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase0101
Sphingosine 1-phosphate receptor 10235
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20304
Sphingosine kinase 10304
Chain B, Cell division protein kinase 60101
1-deoxy-D-xylulose 5-phosphate reductoisomerase0303
Potassium voltage-gated channel subfamily D member 20303
unnamed protein product0101
Lanosterol 14-alpha demethylase0112
Cytochrome P450 11B1, mitochondrial0404
Cytochrome P450 11B2, mitochondrial0505
Lanosterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
likely tRNA 2'-phosphotransferase0101
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
Chain A, PROTEIN (TRANSTHYRETIN)0011
Chain B, PROTEIN (TRANSTHYRETIN)0011
Aldo-keto reductase family 1 member C40606
Transcription factor SOX-180202
Aldo-keto reductase family 1 member C10909
Transcriptional enhancer factor TEF-30112
Potassium channel subfamily K member 180112
Acid-sensing ion channel 50011
Chain A, Uracil Phosphoribosyltransferase0101
Potassium voltage-gated channel subfamily C member 10101
Gastrin/cholecystokinin type B receptor 0101
Acid-sensing ion channel 30202
Chain A, Dihydrofolate reductase0011
Multidrug resistance associated protein0103
Menin0011
Lecithin retinol acyltransferase0101
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Fucose-binding lectin PA-IIL0202
CD209 antigen0303
NADP-dependent malic enzyme, mitochondrial0002
Corticosteroid 11-beta-dehydrogenase isozyme 10314
Holo-[acyl-carrier-protein] synthase0101
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
Voltage-dependent calcium channel subunit alpha-2/delta-10202
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
TPA: protein transporter TIM230202
Protein disulfide-isomerase0202
fructose-bisphosphate aldolase A3003
Anthrax toxin receptor 20303
Polypeptide N-acetylgalactosaminyltransferase 20112
Toll-like receptor 2 0101
Thioredoxin0101
Thioredoxin, mitochondrial0101
Gamma-aminobutyric acid receptor subunit rho-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
4-aminobutyrate aminotransferase, mitochondrial0001
Sterol O-acyltransferase 10011
Platelet glycoprotein VI0247
Sodium- and chloride-dependent GABA transporter 20101
Caspase 6, apoptosis-related cysteine peptidase0003
Toll-like receptor 70136
Ras-related C3 botulinum toxin substrate 10044
epidermal growth factor receptor isoform a precursor2204
Cytochrome P450 2E10303
Quinolone resistance protein NorA0304
Mitogen-activated protein kinase kinase kinase 80202
Synaptic vesicular amine transporter0415
Serine/threonine-protein kinase ULK30044
Chain A, DEOXYNUCLEOSIDE KINASE0101
Guanylate cyclase soluble subunit alpha-10011
Guanylate cyclase soluble subunit beta-10011
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Alpha-mannosidase0101
Maltase-glucoamylase, intestinal0303
Steroid hormone receptor ERR20101
Tyrosinase0606
Steroid hormone receptor ERR10303
Ornithine decarboxylase0202
Solute carrier family 2, facilitated glucose transporter member 40202
Amine oxidase [flavin-containing] A 0404
Cystic fibrosis transmembrane conductance regulator0011
Alpha-glucosidase MAL320101
Amine oxidase [flavin-containing] B0505
DNA (cytosine-5)-methyltransferase 3-like0101
DNA (cytosine-5)-methyltransferase 3A0101
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
luciferase5005
Glutamate receptor ionotropic, kainate 11103
Glutamate receptor ionotropic, kainate 21103
Glutamate receptor ionotropic, kainate 41103
Glutamate receptor ionotropic, kainate 51103
Jak1 protein0101
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0336
Glucagon receptor0011
Glucagon receptor0011
Asialoglycoprotein receptor 10112
Chain A, Glutamine Binding Protein0011
Asc-type amino acid transporter 10202
ATP-binding cassette sub-family C member 90202
ATP synthase subunit beta, mitochondrial0101
ATP synthase subunit delta, mitochondrial0101
ATP synthase subunit gamma, mitochondrial0101
ATP synthase subunit epsilon, mitochondrial0101
Cholesteryl ester transfer protein0101
ATP-binding cassette sub-family C member 80303
ATP-sensitive inward rectifier potassium channel 110404
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 109010
Sodium- and chloride-dependent glycine transporter 20101
High mobility group protein B10033
High mobility group protein B10001
Corticosteroid 11-beta-dehydrogenase isozyme 20112
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Glutamine synthetase 0101
Cytochrome P450 71B10102
Glutamine synthetase 0101
2-dehydro-3-deoxyphosphooctonate aldolase0101
Peroxisome proliferator-activated receptor delta0112
Peroxisome proliferator-activated receptor delta0539
Ricin0202
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0022
Purine nucleoside phosphorylase 0024
Chain A, ELONGATION FACTOR TU (EF-TU)0011
Chain A, Elongation Factor G0011
Chain A, ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 30011
Chain A, Eukaryotic peptide chain release factor GTP-binding subunit0011
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b0011
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b0011
Chain A, interferon-inducible GTPase0011
Chain A, interferon-inducible GTPase0011
Chain A, Elongation factor 20011
Chain A, Guanine nucleotide-binding protein G(i), alpha-1 subunit0011
Ras-related protein Rab-7a0022
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT50101
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90404
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
Vitamin D-binding protein0101
5-hydroxytryptamine receptor 2A0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Calcitonin gene-related peptide type 1 receptor0101
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Chain E, Fibrin beta chain0202
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
CDK50001
major prion protein preproprotein Prp precursor0101
Chain A, TYROSINE PHOSPHATASE0101
Chain A, Tyrosine Phosphatase0101
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10303
SUMO-10202
Estrogen receptor 10303
heat shock 70kDa protein 1A0202
neuropeptide Y receptor type 10011
neuropeptide Y receptor type 20011
small ubiquitin-related modifier 2 isoform b precursor0101
estrogen receptor beta isoform 10404
enteropeptidase precursor1001
fatty acid synthase0101
heat shock cognate 71 kDa protein isoform 10202
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
heat shock cognate 71 kDa protein isoform 20202
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
BZLF20101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
Metabotropic glutamate receptor 50314
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Equilibrative nucleoside transporter 40001
Histamine H4 receptor 0202
Chain A, HISTIDINE-BINDING PROTEIN0011
Histidine-binding periplasmic protein0011
Phosphatidylcholine-sterol acyltransferase0011
G-protein coupled receptor 10011
Cyclic GMP-AMP synthase0202
Toll-like receptor 90101
Uracil nucleotide/cysteinyl leukotriene receptor0404
Glutamine synthetase0101
Ribonucleoside-diphosphate reductase large subunit0101
Dopamine beta-hydroxylase0101
Corticotropin-releasing factor receptor 10101
Cystathionine beta-synthase0101
Cysteine protease ATG4B0101
Chain A, Purine-nucleoside Phosphorylase0101
Chain C, Xanthine dehydrogenase/oxidase0011
Prostaglandin G/H synthase 10404
Caspase-40303
Caspase-50303
Caspase-90303
Dehydrogenase/reductase SDR family member 90101
Cysteinyl leukotriene receptor 10304
Cysteinyl leukotriene receptor 20527
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Prostacyclin receptor0112
Peptidyl-prolyl cis-trans isomerase FKBP50213
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Beta-lactamase 0102
Envelope glycoprotein0033
7,8-dihydro-8-oxoguanine triphosphatase0202
Toll-like receptor 80024
Tyrosine-protein kinase JAK2 0011
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, PROTEIN (PROTEASE)0101
Chain B, PROTEIN (PROTEASE)0101
Chain A, PROTEIN (PROTEASE)0101
Chain B, PROTEIN (PROTEASE)0101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, HIV-II PROTEASE0101
Chain B, HIV-II PROTEASE0101
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, POL polyprotein0011
Chain B, POL polyprotein0011
Chain A, protease RETROPEPSIN0101
Chain B, protease RETROPEPSIN0101
Chain A, protease RETROPEPSIN0101
Chain B, protease RETROPEPSIN0101
Chain A, protease RETROPEPSIN0101
Chain B, protease RETROPEPSIN0101
Chain A, POL polyprotein0202
Chain B, POL polyprotein0202
Chain A, POL polyprotein0202
Chain B, POL polyprotein0202
Chain A, HIV-1 protease0101
Chain B, HIV-1 protease0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Gag-Pol polyprotein0505
Gag-Pol polyprotein0303
Gag polyprotein0202
Gag-Pol polyprotein0303
Gag-Pol polyprotein0303
Thromboxane-A synthase0104
Protease 0101
Malate dehydrogenase0606
Kit ligand0101
Chain A, membrane-associated prostaglandin E synthase-20101
Phospholipase A2, major isoenzyme0303
C-X-C chemokine receptor type 30303
Prostaglandin D2 receptor 0202
Dehydrogenase/reductase SDR family member 90101
Prostaglandin D2 receptor 20213
transcription factor p65 isoform 10022
Estrogen receptor beta0225
Estrogen receptor0225
Survival motor neuron protein0001
Chain A, ADENOSINE DEAMINASE0101
Chain A, ADENOSINE DEAMINASE0101
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Sodium/myo-inositol cotransporter 20101
Chain A, BETA-SPECTRIN0011
Chain A, Phospholipase C Delta-10011
Chain A, Inositol 1,4,5-trisphosphate receptor type 10011
Inositol-trisphosphate 3-kinase A0101
Inositol 1,4,5-trisphosphate receptor type 1 0022
Inositol 1,4,5-trisphosphate receptor type 20101
Inositol 1,4,5-trisphosphate receptor type 30112
Inositol polyphosphate-5-phosphatase A0101
Inositol 1,4,5-trisphosphate receptor type 10112
citrate synthase 2, partial0011
Secreted chorismate mutase0404
Amine oxidase [flavin-containing] B0202
Chain A, meta-Cleavage product hydrolase0101
Free fatty acid receptor 30011
Acetylcholinesterase0112
Fatty acid synthase 0101
Liver carboxylesterase0101
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a0011
3-oxoacyl-[acyl-carrier-protein] synthase 3 0202
N-glycosylase/DNA lyase0202
Formamidopyrimidine-DNA glycosylase0101
Endonuclease III-like protein 10101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0303
Endonuclease 8-like 10101
Beta-2 adrenergic receptor0112
Beta-3 adrenergic receptor0011
Vasopressin V1a receptor0011
Beta-2 adrenergic receptor0213
Taste receptor type 2 member 380024
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310022
Taste receptor type 2 member 450011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600022
Oxytocin receptor0011
Taste receptor type 2 member 420011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140023
Taste receptor type 2 member 130022
Taste receptor type 2 member 100011
Taste receptor type 2 member 90022
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40022
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Ornithine decarboxylase0002
Isocitrate lyase 10101
Histamine H1 receptor 0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Dual specificity protein phosphatase 10303
Dual specificity protein phosphatase 60303
rac GTPase-activating protein 1 isoform a0202
Protein E60202
E3 ubiquitin-protein ligase XIAP0202
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Camphor 5-monooxygenase0001
Steroid 21-hydroxylase0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0303
Cytochrome P450 7A1 0101
Gonadotropin-releasing hormone receptor0314
Cytochrome P450 4F20202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Vesicular glutamate transporter 30101
Leukotriene C4 synthase0202
Macrophage-expressed gene 1 protein0101
Leukotriene C4 synthase0001
Prostaglandin E synthase 20101
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, Galectin-30011
Chain A, Anti-tumor lectin0101
Galectin-30101
Galectin-90011
Galectin-80011
Beta-galactoside-binding lectin0101
Galectin-10113
Galectin-30112
Galectin-30113
Galectin-70011
Alpha 1,4 galactosyltransferase0001
phosphoethanolamine/phosphocholine phosphatase isoform 10101
WD repeat-containing protein 50202
Histone-lysine N-methyltransferase 2A0202
Cytosolic endo-beta-N-acetylglucosaminidase0202
Dihydroorotate dehydrogenase 0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0617
Chain A, Epidermal growth factor receptor0101
Alpha-1A adrenergic receptor 0101
matrix metalloproteinase 1, partial0011
Dihydroorotate dehydrogenase (quinone), mitochondrial0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0202
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Zinc finger protein Aiolos0011
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Intestinal-type alkaline phosphatase0505
Phospholipase A-2-activating protein0505
Gonadotropin-releasing hormone receptor0101
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0303
Intestinal-type alkaline phosphatase0202
integrase, partial0303
lens epithelium-derived growth factor p750303
SLC16A10 protein0004
Monocarboxylate transporter 100004
Potassium channel subfamily K member 30202
Dipeptidyl peptidase 90101
Dipeptidyl peptidase IV0101
Prolyl endopeptidase FAP0101
Prolyl endopeptidase FAP0101
Dipeptidyl peptidase 80101
Dipeptidyl peptidase 90101
Dipeptidyl peptidase 20101
Sterol O-acyltransferase 10303
Dual specificity protein phosphatase 30202
N-formyl peptide receptor 20123
inositol monophosphatase 12002
Protein polybromo-10112
Sodium-dependent neutral amino acid transporter B(0)AT20101
Potassium channel subfamily K member 90101
Type-1 angiotensin II receptor0213
Chain A, Antigen Cd11a (p180)0101
Integrin beta-20101
Intercellular adhesion molecule 10101
Integrin alpha-L0112
Acyl-CoA:cholesterol acyltransferase 0202
Queuine tRNA-ribosyltransferase0101
histidine kinase 0101
Chemotaxis protein CheA0101
Cytosol aminopeptidase0202
DNA topoisomerase 10101
serine/threonine-protein kinase 33 isoform a0022
Interleukin-20011
Platelet-activating factor acetylhydrolase0304
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Lysophosphatidic acid receptor 60011
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
Lysophosphatidic acid receptor 4 0011
Lysophosphatidic acid receptor 10022
Lysophosphatidic acid receptor 40011
Lysophosphatidic acid receptor 50011
Lysophosphatidic acid receptor 20011
Lysophosphatidic acid receptor 30011
Sialidase A0202
Phosphatidylcholine:ceramide cholinephosphotransferase 1 0101
Phosphatidylcholine:ceramide cholinephosphotransferase 20101
Phosphatidylcholine:ceramide cholinephosphotransferase 10101
Phosphatidylcholine:ceramide cholinephosphotransferase 20101
Glutathione S-transferase Mu 10101
Alpha-mannosidase 2C10101
Gastrin/cholecystokinin type B receptor0325
RNA polymerase beta subunit (EC 2.7.7.6), partial0101
14-3-3 protein gamma0101
Lipoxygenase 0101
Proto-oncogene c-Fos0101
Transcription factor AP-10202
Cytochrome P450 11B1, mitochondrial0303
Seed linoleate 9S-lipoxygenase0101
Polyunsaturated fatty acid 5-lipoxygenase0202
Lipoxygenase 0101
Progesterone receptor010518
Androgen receptor0011
Myc proto-oncogene protein0203
Cytochrome P450 1A2 0202
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0303
Nociceptin receptor0101
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Carboxylic ester hydrolase 0303
Large neutral amino acids transporter small subunit 1 0202
UDP-glucose 6-dehydrogenase0101
UDP-glucose 6-dehydrogenase0101
UDP-glucuronosyltransferase 1A1 0101
Neuraminidase0101
Cystathionine gamma-lyase0404
Cystine/glutamate transporter0202
Hydroxyacid oxidase 10101
Multidrug transporter MdfA0303
Aldehyde oxidase 1 0202
Dopamine beta-hydroxylase 0203
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Thymidylate synthase 0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Thymidylate synthase0202
Folate receptor beta0101
Folate receptor alpha0101
Histidine decarboxylase0134
Reduced folate transporter0202
Pteridine reductase 10202
Bifunctional dihydrofolate reductase-thymidylate synthase0405
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0303
Proton-coupled folate transporter0101
Cytochrome P450 2A130437
T cell receptor, partial1001
luteinizing hormone receptor1001
Apoptotic peptidase activating factor 10101
caspase-9 isoform alpha precursor0101
Glutathione reductase0102
Dihydrolipoyl dehydrogenase, mitochondrial0103
Dihydrolipoyl dehydrogenase 0102
Acidic phospholipase A2 20202
Serine racemase0101
Thioredoxin reductase 0101
Flavodoxin0001
5-hydroxytryptamine receptor 3B0202
G-protein coupled receptor 0101
Cytochrome P450 1A20101
methionyl-tRNA synthetase, putative0101
Chain A, PROGESTERONE RECEPTOR0101
Glucocorticoid receptor 0101
Tegument protein VP160011
Glucocorticoid receptor0112
Progesterone receptor0011
Glucocorticoid receptor0101
Platelet-activating factor receptor0202
S-adenosylmethionine decarboxylase proenzyme0102
S-adenosylmethionine decarboxylase proenzyme0203
Chain A, Probable serine/threonine-protein kinase pknB0101
phospholipase A2, group III0101
histone-lysine N-methyltransferase NSD2 isoform 10001
Nuclear receptor corepressor 10303
Acyl-CoA desaturase 10202
Nociceptin receptor0101
Mu-type opioid receptor0101
Chain A, Isoleucyl-tRNA synthetase0101
twin arginine protein translocation system - TatA protein0003
Isoleucine--tRNA ligase0101
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase0202
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A80004
Carboxypeptidase B20202
Prostaglandin E synthase0101
Presenilin-10101
Presenilin-20101
Gamma-secretase subunit APH-1B0101
Nicastrin0101
Gamma-secretase subunit APH-1A0101
Gamma-secretase subunit PEN-20101
Sialidase-40202
Sialidase-10202
Sialidase-30202
Formyl peptide receptor-related sequence 10011
fMet-Leu-Phe receptor0325
FML2_HUMAN 0011
Trace amine-associated receptor 10022
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10002
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Adenosine receptor A10303
Adenosine receptor A10202
Adenosine receptor A2a0101
Adenosine receptor A30101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Nociceptin receptor0101
Hormone-sensitive lipase0101
Chain A, Hth-type Transcriptional Regulator Ttgr0011
Chain A, Hth-type Transcriptional Regulator Ttgr0011
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
G protein-activated inward rectifier potassium channel 20011
G protein-activated inward rectifier potassium channel 40011
G protein-activated inward rectifier potassium channel 10011
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
Neurotensin receptor type 10011
Neurotensin receptor type 20214
Myelin basic protein0011
Neurotensin receptor type 10315
Neurotensin receptor type 10349
Neurotensin receptor type 20325
Sortilin0202
Chain B, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain B, Hiv-1 Reverse Transcriptase0101
Chain A, Reverse transcriptase/ribonuclease H0101
Gag-Pol polyprotein0101
Imidazoleglycerol-phosphate dehydratase0101
Ryanodine receptor 10101
Exoribonuclease H 0303
Cardiac ryanodine receptor 2 0101
Cholesteryl ester transfer protein0303
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20112
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent protein deacetylase HST20202
NAD(+) hydrolase SARM10303
NAD-dependent protein deacetylase sirtuin-60203
NAD-dependent protein deacetylase 0101
Anoctamin-10202
Neuronal acetylcholine receptor subunit alpha-40213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50022
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Microphthalmia-associated transcription factor0003
Platelet-derived growth factor receptor beta0404
Platelet-derived growth factor receptor alpha 0303
Vascular endothelial growth factor receptor 20303
Pyruvate-flavodoxin oxidoreductase0101
Aromatic-L-amino-acid decarboxylase0202
Sodium/iodide cotransporter0101
Lysine-specific demethylase 4C0303
Snake venom metalloproteinase BaP10101
Tubulin beta 8B0011
Chain A, Gyrase0011
DNA gyrase subunit B0101
DNA gyrase subunit B0101
Cell division inhibitor SulA0001
DNA gyrase subunit B0101
Heat shock protein HSP 900101
DNA topoisomerase 4 subunit B0101
DNA topoisomerase 0101
Microtubule-associated proteins 1A/1B light chain 3B0213
Microtubule-associated proteins 1A/1B light chain 3A0213
Signal transducer and activator of transcription 10101
Signal transducer and activator of transcription 3 0101
Methylated-DNA--protein-cysteine methyltransferase0102
Solute carrier family 22 member 190001
STE240001
Neurogenic locus notch homolog protein 10101
Phosphotyrosine protein phosphatase 0101
Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]0011
Receptor-type tyrosine-protein phosphatase alpha0202
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0022
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0022
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0022
putative potassium channel subunit0011
Nitric oxide synthase, brain0101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
Bombesin receptor subtype-30011
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Solute carrier family 2, facilitated glucose transporter member 90224
Neuraminidase 0202
Neuraminidase 0202
Neuraminidase0202
Acyl-CoA desaturase 10202
Neuraminidase 0202
Neuraminidase 0202
Neuraminidase0101
Neuraminidase0101
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)0101
Chain L, Igg2b-kappa 40-50 Fab (light Chain)0101
Chain A, Na, K-ATPase alpha subunit0011
Kruppel-like factor 50101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-30101
MecA 0101
Lysine-specific demethylase 6B0101
Kynurenine 3-monooxygenase0101
Lysine-specific demethylase 4A0101
Lysine-specific demethylase 5C0101
Prolyl 4-hydroxylase subunit alpha-10202
Peptidyl-prolyl cis-trans isomerase A 0101
Methylcytosine dioxygenase TET20101
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial0101
Lysine-specific demethylase 5D0101
Lysine-specific demethylase 5B0101
Lysine-specific demethylase 2A0101
Lysine-specific demethylase 3A0101
voltage-dependent T-type calcium channel subunit alpha-1H isoform a0011
P2X purinoceptor 70202
Cholecystokinin receptor type A0538
Beta-tubulin 0101
Chain B, Cell division protein kinase 60101
Chain B, Cell division protein kinase 60101
Cyclin-K0202
G1/S-specific cyclin-D20101
Chain A, Fatty acid-binding protein, adipocyte0101
Toll-like receptor 20101
Geranylgeranyl pyrophosphate synthase0303
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0101
Type II pantothenate kinase0001
Type III pantothenate kinase0001
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
Serine hydroxymethyltransferase, mitochondrial0202
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 0202
Beta-adrenergic receptor kinase 10202
Rhodopsin kinase GRK10101
G protein-coupled receptor kinase 50303
G protein-coupled receptor kinase 50101
Beta-adrenergic receptor kinase 10001
Testosterone 17-beta-dehydrogenase 30101
Putative nucleoside diphosphate kinase0022
Nucleoside diphosphate kinase B0022
Nuclear receptor subfamily 4 group A member 30101
Peroxiredoxin-like 2A0101
Tyrosine-protein kinase transforming protein Abl0101
Protein kinase C alpha type0202
Fructose-1,6-bisphosphatase 1 0101
Luciferin 4-monooxygenase0213
Dual specificity mitogen-activated protein kinase kinase 2 0101
Dual specificity mitogen-activated protein kinase kinase 1 0101
Beta-lactamase 10001
Beta-lactamase 0002
Chain A, CATHEPSIN D0101
Chain B, CATHEPSIN D0101
Chain A, PLASMEPSIN II0101
Chain E, ENDOTHIAPEPSIN0101
Chain E, RHIZOPUSPEPSIN0101
Chain E, ENDOTHIAPEPSIN0101
Chain E, ENDOTHIAPEPSIN0101
Chain E, RHIZOPUSPEPSIN0101
Chain E, RHIZOPUSPEPSIN0101
Cathepsin D0304
Pro-cathepsin H0101
Candidapepsin-20101
Pepsin A-50101
Gag-Pro polyprotein0101
Cathepsin E0101
Plasmepsin-10101
Plasmepsin-20101
Disintegrin and metalloproteinase domain-containing protein 90101
Plasmepsin 4 0101
Cysteine protease0101
Chymotrypsin-C0202
Chain A, Mitogen-activated protein kinase 140101
Chain A, Mitogen-activated protein kinase 140101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Cholinesterase0202
Muscarinic acetylcholine receptor M50113
Muscarinic acetylcholine receptor M30113
Muscarinic acetylcholine receptor M20113
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Alpha-1A adrenergic receptor0011
Alpha-1B adrenergic receptor0101
fMet-Leu-Phe receptor0202
Cyclooxygenase-2 0101
Sodium/glucose cotransporter 1 0101
Sodium/glucose cotransporter 20101
Solute carrier family 5 member 40101
Protein kinase C gamma type0628
Proto-oncogene vav0011
Protein kinase C delta type0112
Transient receptor potential cation channel subfamily V member 4 0011
Chain A, Alkaline Phosphatase0101
Chain A, ALKALINE PHOSPHATASE0101
Fe(3+)-Zn(2+) purple acid phosphatase0101
Muscarinic acetylcholine receptor DM10202
CDGSH iron-sulfur domain-containing protein 10202
Peroxisome proliferator-activated receptor gamma0101
Carnitine O-palmitoyltransferase 2, mitochondrial0202
CDGSH iron-sulfur domain-containing protein 20202
Amine oxidase [flavin-containing] A0101
Transforming growth factor beta-1 proprotein0101
Mothers against decapentaplegic homolog 3 0101
Dihydrofolate reductase 0203
Dihydrofolate reductase0202
Dihydrofolate reductase0404
Dihydrofolate reductase 0202
Chain A, AKAP9-BRAF fusion protein0101
Dual specificity mitogen-activated protein kinase kinase 40011
Aspartyl/asparaginyl beta-hydroxylase0101
Regulatory protein E20011
Regulatory protein E20011
Calcium-activated potassium channel subunit alpha-10101
Sphingosine 1-phosphate receptor 30123
Sodium/potassium/calcium exchanger 40112
Sodium/potassium/calcium exchanger 20112
luciferase0001
Glutamine synthetase0011
Nociceptin receptor0011
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Pannexin-10101
Solute carrier family 22 member 120202
Pannexin-10101
Low molecular weight protein-tyrosine phosphatase A0101
Trace amine-associated receptor 10022
Trace amine-associated receptor 10134
Glutamate 5-kinase0001
Nuclear receptor subfamily 2 group E member 10033
NADH-cytochrome b5 reductase 3 0101
Thyroid peroxidase0101
Coproheme decarboxylase0011
Interleukin-50101
Interleukin-50101
Interleukin-5 receptor subunit alpha0101
Puromycin-sensitive aminopeptidase0202
Chain A, PUTRESCINE-BINDING PROTEIN0011
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN0101
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN0101
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN0101
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN0101
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
polyadenylate-binding protein 10202
Serine/threonine-protein kinase 30033
Trans-sialidase0101
Trans-sialidase0101
dual specificity protein phosphatase 30101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
Beta-hexosaminidase subunit alpha0102
Beta-hexosaminidase subunit beta0101
Substance-K receptor0224
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Monocarboxylate transporter 20001
C-terminal-binding protein 20101
Chain A, APH(2')-Id0101
glucose-6-phosphate dehydrogenase0101
hexokinase0202
B2 bradykinin receptor0404
Chymotrypsin-like elastase family member 10202
Epoxide hydrolase 1 0101
Lysosomal alpha-glucosidase0101
Solute carrier family 2, facilitated glucose transporter member 20101
Sucrase-isomaltase, intestinal0101
Solute carrier family 2, facilitated glucose transporter member 4 0101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10202
Oligo-1,6-glucosidase IMA10101
Aldo-keto reductase family 1 member B10101
ELAV-like protein 30101
ELAV-like protein 10101
Probable maltase-glucoamylase 20101
Aldo-keto reductase family 1 member C210202
N0101
DNA-directed RNA polymerase subunit alpha0101
DNA-directed RNA polymerase subunit omega0101
DNA-directed RNA polymerase subunit beta'0101
DNA-directed RNA polymerase subunit beta0101
Phospholipase A2, membrane associated0101
Multidrug resistance protein 1a0001
Advanced glycosylation end product-specific receptor0011
Advanced glycosylation end product-specific receptor0011
Vascular endothelial growth factor receptor 30202
Chromaffin granule amine transporter0101
Synaptic vesicular amine transporter0314
Synaptic vesicular amine transporter0202
Chain A, Bacterial regulatory proteins, tetR family0011
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
cathepsin L10101
Aryl hydrocarbon receptor0101
DNA polymerase alpha catalytic subunit0101
N1L 0101
NAD(P)H dehydrogenase [quinone] 10005
Lysosomal alpha-glucosidase0202
Chain A, Cellular retinoic acid-binding protein 20011
Chain A, Cellular retinoic acid-binding protein 20011
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Beta-lactoglobulin0011
MSRA protein0101
plectin 10101
Type 1 InsP3 receptor isoform S2 1001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Genome polyprotein0011
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0202
Arylacetamide deacetylase0102
DNA-directed RNA polymerase subunit beta0101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Gag-Pol polyprotein0202
Plasmepsin V 0101
Acetylcholine receptor subunit epsilon0101
Cholinesterase0101
Serine/threonine-protein kinase VRK10101
Prostaglandin G/H synthase 20101
Cytochrome c oxidase subunit 10101
Calpain-2 catalytic subunit0101
Transporter0101
Sodium-dependent serotonin transporter0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Retina-specific copper amine oxidase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Endothelin-1 receptor0101
Thrombin 0011
Linoleate 9S-lipoxygenase-40101
UDP-galactopyranose mutase0011
UDP-galactopyranose mutase0011
Eukaryotic elongation factor 2 kinase0101
Ubiquitin carboxyl-terminal hydrolase 10202
WD repeat-containing protein 480202
RuvB-like 10202
Neuromedin-U receptor 20022
Proto-oncogene tyrosine-protein kinase Src0213
Low-density lipoprotein receptor0101
Fibronectin0101
Macrophage colony-stimulating factor 1 receptor0101
Proprotein convertase subtilisin/kexin type 90101
Met repressor 0022
Protein arginine N-methyltransferase 50011
Histone H3K27 methylase0001
Phenylethanolamine N-methyltransferase0012
Protein-L-isoaspartate(D-aspartate) O-methyltransferase0101
Catechol O-methyltransferase0001
Protein arginine N-methyltransferase 10101
Methylosome protein 500011
Renin0101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Tyrosine-protein phosphatase YopH0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Chain A, Hiv-1 Protease0101
Chain B, Hiv-1 Protease0101
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Bromodomain testis-specific protein0101
Tau-tubulin kinase 10101
Tau-tubulin kinase 20101
Chain A, Erk20101
Mitogen-activated protein kinase 20101
Mitogen-activated protein kinase 14 0213
Mitogen-activated protein kinase 10101
P2X purinoceptor 70101
Heat shock protein beta-10101
Transcriptional activator protein LuxR0303
Sterol O-acyltransferase 20101
Tyrosine-protein phosphatase 10101
Pyruvate kinase PKLR0101
Neuraminidase0101
photoreceptor-specific nuclear receptor0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Cholecystokinin receptor type A0101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Programmed cell death protein 40011
Serine/threonine-protein kinase mTOR 0101
Kallikrein-10101
Chymotrypsin-like elastase family member 2A0101
Myeloblastin0101
Neutrophil elastase0101
Butyrophilin subfamily 3 member A10101
RNA-directed RNA polymerase 0124
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Tyrosine-protein kinase ABL10101
Protein delta homolog 10123
Vascular endothelial growth factor receptor 20101
RuvB-like 20112
Protein kinase C beta type 0101
Sulfate anion transporter 10001
C-X-C chemokine receptor type 5 isoform 10101
C-C chemokine receptor type 60101
Endoglycoceramidase II 0001
cAMP-dependent protein kinase catalytic subunit alpha 0202
Sphingosine 1-phosphate receptor 20112
Sphingosine 1-phosphate receptor 40112
Sphingosine 1-phosphate receptor 50112
neurotensin receptor type 10011
Nuclear receptor subfamily 1 group D member 10123
Nuclear receptor subfamily 1 group D member 20101
Thioredoxin glutathione reductase 0101
Chain A, Serine/threonine-protein kinase Chk10101
Chain A, Serine/threonine-protein kinase Chk10101
Chain A, Serine/threonine-protein kinase Chk10101
Chain A, Glycogen Synthase Kinase-3 Beta0101
Chain B, Glycogen Synthase Kinase-3 Beta0101
Chain A, Glycogen Synthase Kinase-3 Beta0101
Chain E, Camp-dependent Protein Kinase0101
Chain A, Tyrosine-protein kinase ZAP-700101
Chain A, Tyrosine-protein kinase SYK0101
Chain A, Protein kinase C, theta type0101
Chain X, Proto-oncogene tyrosine-protein kinase Fyn0101
Chain A, Serine/threonine-protein kinase TAO20101
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha10001
dual specificity mitogen-activated protein kinase kinase 11001
RAF proto-oncogene serine/threonine-protein kinase isoform b1001
Casein kinase II subunit alpha'0101
Cyclin-T20101
Retinoblastoma-associated protein 0101
Cyclin-dependent kinase 1 0101
Insulin receptor0101
Cyclin-O0101
Kinesin-1 heavy chain0101
Hexokinase-40101
Beta-adrenergic receptor kinase 20101
Phosphorylase b kinase regulatory subunit alpha, liver isoform0101
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform0101
Mitogen-activated protein kinase 1 0101
Casein kinase II subunit beta0101
Epidermal growth factor receptor0101
Lysine--tRNA ligase0101
TGF-beta-activated kinase 1 and MAP3K7-binding protein 10101
Coiled-coil domain-containing protein 60101
Rho-associated protein kinase 20202
Mitogen-activated protein kinase kinase kinase 210101
Casein kinase II subunit alpha 0101
Testis-specific serine/threonine-protein kinase 10101
Calcium/calmodulin-dependent protein kinase type 1B0101
Kinase suppressor of Ras 20101
Serine/threonine-protein kinase Nek80101
Casein kinase II subunit alpha'-interacting protein0101
Kinase suppressor of Ras 10101
Cyclin-Y0101
Protein odd-skipped-related 10101
Serine/threonine-protein kinase haspin0101
Phosphorylase b kinase regulatory subunit beta0101
Lymphokine-activated killer T-cell-originated protein kinase0101
Testis-specific serine/threonine-protein kinase 20101
Testis-specific serine/threonine-protein kinase 30101
Serine/threonine-protein kinase LMTK30101
Mitogen-activated protein kinase kinase kinase 140101
Testis-specific serine/threonine-protein kinase 60101
Serine/threonine-protein kinase WNK10101
Inactive tyrosine-protein kinase PEAK10101
Serine/threonine-protein kinase Sgk20101
Ribosomal protein S6 kinase beta-20101
Protein DBF4 homolog A0101
Serine/threonine-protein kinase WNK20101
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
Zinc finger protein GLI20101
Thymidine kinase, cytosolic 0104
Mast/stem cell growth factor receptor Kit0101
Bromodomain-containing protein 90011
Bromodomain-containing protein 70011
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Chain A, Protein (aspartate Aminotransferase)0011
Chain A, Aspartate Aminotransferase0011
Delta-aminolevulinic acid dehydratase0101
Solute carrier family 13 member 30101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Protein argonaute-20022
Chain A, Glutathione S-transferase0101
Fibroblast growth factor 10011
Hematopoietic prostaglandin D synthase0202
Transcription regulator protein BACH10101
Transcription factor MafK 0101
Nuclear factor erythroid 2-related factor 20001
Kelch-like ECH-associated protein 10001
Orexin receptor type 10202
Orexin receptor type 20202
Orexin receptor type 10101
Orexin receptor type 20101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0202
Splicing factor 3B subunit 30101
Chain A, CES1 protein0101
Phospholipase D1 0101
Emopamil-binding protein-like0202
7-dehydrocholesterol reductase0112
Chain A, Prostatic Acid Phosphatase0101
Beta-lactamase 0101
Beta-lactamase0101
Beta-lactamase OXA-10102
Metallo-beta-lactamase type 20101
Metallo-beta-lactamase L1 type 30101
Beta-lactamase 0101
Beta-lactamase 0101
Stromal interaction molecule 10101
Dihydroorotate dehydrogenase 0202
Tetracycline resistance protein, class B0001
Neutrophil collagenase0101
Ras guanyl-releasing protein 30011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Adenosine receptor A10101
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
1-deoxy-D-xylulose-5-phosphate synthase0011
1-deoxy-D-xylulose-5-phosphate synthase0011
Urease subunit alpha0101
Urease subunit beta 0101
E3 ubiquitin-protein ligase Mdm2 isoform a0011
Gamma-butyrobetaine dioxygenase0112
Thymidine phosphorylase0001
Thymidine kinase 0204
Thymidine kinase0103
Thymidine phosphorylase0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain B, Odorant-binding Protein0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Malate dehydrogenase, mitochondrial0101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
P2Y purinoceptor 130101
Chain A, Tyrosine-protein kinase0101
Chain A, Tyrosine-protein kinase0101
Chain A, Tyrosine-protein kinase JAK20101
Tyrosine-protein kinase JAK30101
Tyrosine-protein kinase JAK20101
Tyrosine-protein kinase JAK30101
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 20101
MSH0001
Transient receptor potential cation channel subfamily V member 20101
Cytochrome P450 4B10101
Cytochrome P450 2A70101
Cytochrome P450 2F10101
Cytochrome P450 2C180101
Cytochrome P450 4F80101
Cytochrome P450 4A110101
Cytochrome P450 4F30101
Cytochrome P450 4A220101
Vitamin D 25-hydroxylase0101
Cytochrome P450 2U10101
Cytochrome P450 2W10101
Cytochrome P450 2S10101
Cytochrome P450 3A43 0101
REST corepressor 30202
Chain A, Nuclear Receptor ROR-beta0101
Nuclear receptor ROR-alpha0101
Nuclear receptor ROR-beta0101
procathepsin L isoform 1 preproprotein0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, Repressor0011
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI0202
Enoyl-acyl carrier reductase0101
Enoyl-ACP reductase II 0101
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Calcium-dependent protein kinase 40101
Solute carrier organic anion transporter family member 4A10001
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase type 1 from Tn40030101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Proteinase-activated receptor 20101
Forkhead box protein M10202
Chain A, CARBONIC ANHYDRASE II0101
Indoleamine 2,3-dioxygenase 20202
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
guanine nucleotide-binding protein subunit alpha-150112
D(3) dopamine receptor isoform e1001
trace amine-associated receptor 10112
Phenylethanolamine N-methyltransferase0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
jumonji domain containing 2C, partial0001
Chain A, Bacterial leucyl aminopeptidase0101
Aminopeptidase B0202
M1 family aminopeptidase0202
Cytosol aminopeptidase0202
Aminopeptidase N 0101
Interleukin-1 receptor antagonist protein0101
Cytosol aminopeptidase0202
Aminopeptidase N0202
Leucyl-cystinyl aminopeptidase0101
Bacterial leucyl aminopeptidase0202
Endoplasmic reticulum aminopeptidase 20101
Aminopeptidase B0101
Endoplasmic reticulum aminopeptidase 10101
Chain A, Uracil-DNA Glycosylase0101
Chain A, Cytidine Deaminase0101
Uridine-cytidine kinase 1 0001
P2Y purinoceptor 140011
Chain A, orotidine 5'-monophosphate decarboxylase0101
Chain B, orotidine 5'-monophosphate decarboxylase0101
Chain A, orotidine 5'-monophosphate decarboxylase0101
Chain A, orotidine monophosphate decarboxylase0101
Chain A, orotidine monophosphate decarboxylase0101
Chain B, orotidine monophosphate decarboxylase0101
Chain B, PyrR bifunctional protein0011
Uridine 5'-monophosphate synthase0101
Orotidine 5'-phosphate decarboxylase 0101
Basic phospholipase A2 10101
Hemagglutinin0011
Basic phospholipase A2 PLA-A0101
Acidic phospholipase A2 EC-I0101
Ubiquitin carboxyl-terminal hydrolase 70101
Ubiquitin carboxyl-terminal hydrolase 470101
Sentrin-specific protease 10101
Chain A, Arginase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
D-alanyl-D-alanine dipeptidase0101
Transcription intermediary factor 1-alpha0101
E3 ubiquitin-protein ligase TRIM330101
Glycoprotein0101
Catechol O-methyltransferase0101
Adenosylhomocysteinase0101
Aldehyde oxidase 10101
Aldehyde oxidase 10101
M-phase inducer phosphatase 30101
Aldehyde oxidase 10101
Chain A, Cyclophilin A0011
Chain A, Cyclophilin A0011
Chain A, Histone deacetylase-like amidohydrolase0101
Chain A, Histone deacetylase-like amidohydrolase0101
Histone deacetylase 0101
Gli10101
protein Wnt-3a precursor0101
Histone deacetylase 10202
Protein Tat0011
Leukotriene A-4 hydrolase0101
Apoptosis regulator BAX 0011
Histone deacetylase 10101
Histone deacetylase 0101
Renin0101
Histone deacetylase 30101
Histone deacetylase 0101
HD2 type histone deacetylase HDA106 0202
Histone deacetylase 70101
Histone deacetylase 6 0101
Histone deacetylase 40101
Histone deacetylase 60101
Histone deacetylase 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
fructose-bisphosphate aldolase0101
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0101
Chain B, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, Rho-associated protein kinase 10101
cAMP-dependent protein kinase catalytic subunit alpha 0101
C-C motif chemokine 20101
Farnesyl diphosphate synthase0101
Geranylgeranyl pyrophosphate synthase0202
Alpha-2A adrenergic receptor0101
Lysosomal alpha-glucosidase0101
C-X-C chemokine receptor type 40011
Ectonucleoside triphosphate diphosphohydrolase 10001
Tumor necrosis factor ligand superfamily member 110101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]