Page last updated: 2024-08-05 10:47:59

steroid

Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.

ChEBI ID: 35341

Members (37)

MemberDefinitionRole
(10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one(10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
(13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one(13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
(2s,3r,5r,10r,13r,14s,17s)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2r,3r)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-6-one(2s,3r,5r,10r,13r,14s,17s)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2r,3r)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-6-one
(8R,9S,13S,14R,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(8R,9S,13S,14R,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
16-androsteneA steroid comprising androstane having a C=C double bond at the 16(17)-position.androst-16-ene
24-ethyl-4-cholesten-3-onebeta-sitostenone
27-norcholestane-3,7,12,24,25-pentol27-Nor-5beta-cholestane-3alpha,7alpha,12alpha,24,25-pentol
3 beta-hydroxy-delta 5-cholenic acid3b-Hydroxy-5-cholenoic acid
3-hydroxystigmast-5-en-7-one3-Hydroxystigmast-5-en-7-one
3'-hydroxystanozolol3'-Hydroxystanozolol
ajugasterone cAjugasterone C
allylestrenolAllylestrenol
cevineA steroid consisting of cevane having an oxygen bridge between positions 4 and 9 and carrying seven additional hydroxy substituents.cevine
cholesta-5,8-dien-3 beta-ol8-Dehydrocholesterol
cortivazolcortivazol
demissidineDemissidine
epiestriol13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol
epimestrolEpimestrol
fucosterol24Z-ethylidene-cholest-5-en-3-ol
furazabolFurazabol
gestodenegestodene
gorgosterolGorgosterol
hippurin22-epi-Hippurin-1
lynestrenolLynestrenol
methylestrenoloneNormethandrolone
nivazolnivazol
norgestrienonenorgestrienone
promestrienepromestriene
remikirenSolamargine
spinasterolalpha-Spinasterol
stigmast-4-ene-3,6-dioneStigmast-4-ene-3,6-dione
stigmast-7-enolSchottenol
stigmasterol glucosideStigmasteryl glucoside
turkesteroneTurkesterone
unden3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
veratridineveratridine
zanoteroneZanoterone

Research

Studies (2,015)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,095 (54.34)18.7374
1990's392 (19.45)18.2507
2000's249 (12.36)29.6817
2010's234 (11.61)24.3611
2020's45 (2.23)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials329 (14.60%)5.53%
Reviews79 (3.51%)6.00%
Case Studies106 (4.70%)4.05%
Observational3 (0.13%)0.25%
Other1,736 (77.05%)84.16%