Page last updated: 2024-08-05 12:17:47
monothioacetal
A thioacetal having the structure R2C(OR')(SR'). The term includes monothioketals, R =/= H, as a subclass.
ChEBI ID: 59793
Members (2)
| Member | Definition | Role |
|---|
| emtricitabine | An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection. | emtricitabine |
| lamivudine | A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. | lamivudine |
Research
Studies (7,922)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 813 (10.26) | 18.2507 |
| 2000's | 3,501 (44.19) | 29.6817 |
| 2010's | 2,787 (35.18) | 24.3611 |
| 2020's | 821 (10.36) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 1,889 (21.64%) | 5.53% |
| Reviews | 949 (10.87%) | 6.00% |
| Case Studies | 873 (10.00%) | 4.05% |
| Observational | 129 (1.48%) | 0.25% |
| Other | 4,891 (56.02%) | 84.16% |