tetracycline and Aortic-Valve-Insufficiency

Echocardiographic diagnosis of a case of endocarditis, subsequently proven to be due to a chlamydial organism, is described. Early echocardiographic diagnosis guided initial medical management and directed urgent surgical intervention when the patient deteriorated. Reported cases of chlamydial endocarditis are reviewed.

Topics: Antigens, Bacterial; Aortic Valve Insufficiency; Chlamydophila psittaci; Endocarditis, Bacterial; Heart Valve Prosthesis; Humans; Male; Middle Aged; Psittacosis; Tetracycline

Brucella endocarditis is a rare, but often fatal, complication of brucellosis. A 32 year old man acquired brucellosis while on a visit to his former home in Greece and presented six months later with malaise, fever and aortic regurgitation. Blood cultures grew Brucella melitensis biotype 1. Combined chemotherapy with streptomycin, tetracycline and rifampin sterilized his blood; however, his aortic valve was replaced owing to recurrent emboli and cardiac failure. Over the next 18 months the patient's antibody titer to Brucella fell and his blood reamined sterile. Cure was achieved by resection of the infected aortic valve and 10 weeks of bactericidal therapy for B. melitensis.

Topics: Adult; Aortic Valve Insufficiency; Brucellosis; Drug Therapy, Combination; Endocarditis, Bacterial; Heart Valve Prosthesis; Humans; Male; Rifampin; Streptomycin; Tetracycline

Topics: Aortic Valve; Aortic Valve Insufficiency; Chlamydia; Complement Fixation Tests; Endocarditis; Heart Valve Prosthesis; Humans; Male; Microscopy, Electron; Middle Aged; Rifampin; Tetracycline

Topics: Aortic Valve Insufficiency; Coxiella; Endocarditis, Bacterial; Humans; Male; Middle Aged; Tetracycline

Topics: Adolescent; Adult; Aortic Valve Insufficiency; Aortic Valve Stenosis; Chloramphenicol; Complement Fixation Tests; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Pericarditis; Q Fever; Tetracycline