An organic heterotricyclic compound whose skeleton consists of a diazepine ring which is fused to two pyridine rings.
ChEBI ID: 63667
| Member | Definition | Role |
|---|---|---|
| 12-hydroxynevirapine | A dipyridodiazepine that is nevirapine in which one of the hydrogens of the methyl group has been substituted by a hydroxy group. It is a metabolite of the anti-HIV drug, nevirapine. | 12-hydroxynevirapine |
| nevirapine | A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection. | nevirapine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 357 (11.76) | 18.2507 |
| 2000's | 1,377 (45.37) | 29.6817 |
| 2010's | 1,158 (38.15) | 24.3611 |
| 2020's | 143 (4.71) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 509 (15.82%) | 5.53% |
| Reviews | 202 (6.28%) | 6.00% |
| Case Studies | 162 (5.04%) | 4.05% |
| Observational | 32 (0.99%) | 0.25% |
| Other | 2,312 (71.87%) | 84.16% |