A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
| Member | Definition | Class |
|---|
| 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone | An enone with a trimethylcyclohexenyl substituent at C-1. | 1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-enone |
| 1-hexanol | A primary alcohol that is hexane substituted by a hydroxy group at position 1. | hexan-1-ol |
| 2-ethylfuran | A member of the class of furans that is furan in which the hydrogen atom at position 2 has been replaced by an ethyl group. | 2-ethylfuran |
| 2-methylvaleric acid | A methyl-branched fatty acid that is pentanoic acid which carries a methyl group at position 2. | 2-methylvaleric acid |
| 2-pinene oxide | An epoxide of alpha-pinene. | alpha-pinene oxide |
| 3-hydroxy-3-methylbutene | A tertiary alcohol that is 3-methylbut-1-ene carrying a hydroxy substituent at position 3. | 3-hydroxy-3-methylbut-1-ene |
| 3,5-dimethoxytoluene | A member of the class of toluenes that is toluene in which the hydrogens at positions 3 and 5 have been replaced by methoxy groups. It is the major scent compound of many rose varieties. | 3,5-dimethoxytoluene |
| 4-methylbenzyl alcohol | A methylbenzyl alcohol in which the methyl substituent is para to the hydroxymethyl group. | 4-methylbenzyl alcohol |
| 6-methylcoumarin | A member of the class of coumarins that is coumarin in which the hydrogen at position 6 is replaced by a methyl group. | 6-methylcoumarin |
| benzaldehyde | An arenecarbaldehyde that consists of benzene bearing a single formyl substituent; the simplest aromatic aldehyde and parent of the class of benzaldehydes. | benzaldehyde |
| benzyl alcohol | An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent. | benzyl alcohol |
| benzyl cinnamate | The cinnamate ester derived from cinnamic acid and benzyl alcohol. Occuring in Balsam of Peru and Tolu balsam, in Sumatra and Penang benzoin, and as the main constituent of copaiba balsam, it is used in heavy oriental perfumes, as a fixative and as a flavouring agent. | benzyl cinnamate |
| benzylideneacetone | The trans-isomer of benzylideneacetone. It acts as an inhibitor of the enzyme phospholipase A2 (EC 3.1.1.4) of insects like diamond back moth. | trans-benzylideneacetone |
| beta-damascenone | A cyclic monoterpene ketone that is 2,6,6-trimethylcyclohexa-1,3-diene substituted at position 1 by a crotonoyl group. | beta-damascenone |
| beta-ionone | An ionone that is but-3-en-2-one substituted by a 2,6,6-trimethylcyclohex-1-en-1-yl group at position 4. | beta-ionone |
| camphene | A monoterpene with a bicyclic skeleton that is bicyclo[2.2.1]heptane substituted by geminal methyl groups at position 2 and a methylidene group at position 3. It is a widespread natural product found in many essential oils. | camphene |
| caryophyllene | A beta-caryophyllene in which the stereocentre adjacent to the exocyclic double bond has S configuration while the remaining stereocentre has R configuration. It is the most commonly occurring form of beta-caryophyllene, occurring in many essential oils, particularly oil of cloves. | (-)-beta-caryophyllene |
| civetone | A macrocycle that is cycloheptadecanone with an unsaturation at position 9 (the 9Z-stereoisomer). It has been found in African Civets. | civetone |
| cuminol | A member of the class of benzyl alcohols in which the hydrogen at position 4 on the phenyl ring of benzyl alcohol has been replaced by an isopropyl group. | 4-isopropylbenzyl alcohol |
| decanaldehyde | A saturated fatty aldehyde formally arising from reduction of the carboxy group of capric acid (decanoic acid). | decanal |
| elemol | A sesquiterpenoid that is isopropanol which is substituted at position 2 by a (3S,4S)-3-isopropenyl-4-methyl-4-vinylcyclohexyl group. | elemol |
| ethyl benzoate | A benzoate ester obtained by condensation of benzoic acid and ethanol. It is a volatile oil component found in ripe kiwifruit, cranberry juice, and palm kernel oil. | ethyl benzoate |
| furaneol | A member of the class of furans that is 2,5-dimethylfuran carrying additional oxo and hydroxy groups at positions 3 and 4 respectively. It has been found particularly in strawberries and other such fruits. | 4-hydroxy-2,5-dimethylfuran-3-one |
| galaxolide | An organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively. It is a synthetic musk used as a fragrance in cosmetics. | galaxolide |
| geraniol | A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end. | geraniol |
| geranylacetone | A monoterpene ketone in which an (E)-geranyl group is bonded to one of the alpha-methyls of acetone. It is a component of essential oils from various plants including Nelumbo nucifera. | geranyl acetone |
| heptanol | A primary alcohol that is heptane substituted by a hydroxy group at position 1. It has been isolated from Capillipedium parviflorum. | heptan-1-ol |
| hydroxycitronellal | The tertiary alcohol arising from addition of water across the C=C double bond of citronellal. | hydroxycitronellal |
| linalool | A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum. | linalool |
| methyl acetate | An acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 degreeC) colourless, flammable liquid, it is used as a solvent for many resins and oils. | methyl acetate |
| methyl tetradecanoate | A fatty acid methyl ester resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with methanol. | methyl tetradecanoate |
| musk xylene | A C-nitro compound that is m-xylene bearing three nitro substituents at positions 2, 4 and 6 as well as a tert-butyl group at position 5. | musk xylene |
| myrcene | A monoterpene that is octa-1,6-diene bearing methylene and methyl substituents at positions 3 and 7 respectively. | beta-myrcene |
| nerol | The (2Z)-stereoisomer of 3,7-dimethylocta-2,6-dien-1-ol. It has been isolated from the essential oils from plants like lemon grass. | nerol |
| nootkatone | A sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer). | (+)-nootkatone |
| perillene | A monoterpenoid that is furan in which the hydrogen at position 3 is replaced by a 4-methylpent-3-en-1-yl group. A defensive allomone of thrips that has a flowery, citrus-like flavour. | perillene |
| phenylethyl alcohol | A primary alcohol that is ethanol substituted by a phenyl group at position 2. | 2-phenylethanol |
| piperonal | An arenecarbaldehyde that is 1,3-benzodioxole substituted by a formyl substituent at position 5. It has been isolated from Piper nigrum. | piperonal |
| propyl acetate | An acetate ester obtained by the formal condensation of acetic acid with propanol. | propyl acetate |
| raspberry ketone | A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at position 4 by a hydroxy group. It is found in a variety of fruits including raspberries, blackberries and cranberries, and is used in perfumery and cosmetics. | raspberry ketone |
| sclareol | A labdane diterpenoid that is labd-14-ene substituted by hydroxy groups at positions 8 and 13. It has been isolated from Salvia sclarea. | sclareol |
| zingerone | A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger. | zingerone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 31.6220 | 3 | 8 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 12.8001 | 1 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 14.2923 | 1 | 4 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 31.9944 | 11 | 32 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 36.8746 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 11.5774 | 1 | 1 |
| Ataxin-2 | Homo sapiens (human) | Potency | 6.8590 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 6.8590 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 49.6089 | 2 | 6 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 22.3872 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 28.6786 | 1 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.5193 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 25.0407 | 1 | 3 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 24.5454 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 16.1564 | 2 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 44.1285 | 1 | 6 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 32.3823 | 11 | 51 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 36.8653 | 3 | 10 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 32.9799 | 6 | 31 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 34.1355 | 5 | 11 |
| G | Vesicular stomatitis virus | Potency | 25.0407 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 14.8276 | 2 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 43.8339 | 3 | 18 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 25.9599 | 4 | 8 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 46.5077 | 1 | 7 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 50.6114 | 2 | 7 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 126.7930 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 25.0407 | 1 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 54.9410 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 0.9200 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 25.0407 | 1 | 6 |
| Interferon beta | Homo sapiens (human) | Potency | 25.0407 | 1 | 3 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.0355 | 1 | 1 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 13.9943 | 2 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 38.4002 | 4 | 17 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 30.4167 | 1 | 6 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 42.1632 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 32.8440 | 3 | 20 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0023 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 24.7165 | 2 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 38.8873 | 4 | 7 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 41.7666 | 2 | 14 |
| progesterone receptor | Homo sapiens (human) | Potency | 35.7388 | 2 | 7 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 40.2779 | 2 | 14 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 35.0351 | 3 | 32 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 24.3943 | 2 | 23 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 48.9662 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 48.9662 | 2 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 22.4113 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 3.3498 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 46.0305 | 3 | 15 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 7.2334 | 1 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 23.8592 | 5 | 15 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 22.9441 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 46.4321 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 26.3803 | 5 | 12 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 46.5077 | 1 | 7 |