An agent used to treat cestode, trematode, or other flatworm infestations in man or animals.
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
15-lipoxygenase, partial | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
acetylcholinesterase | Homo sapiens (human) | Potency | 66.4690 | 3 | 6 |
activating transcription factor 6 | Homo sapiens (human) | Potency | 47.0740 | 2 | 5 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 23.7558 | 1 | 1 |
AR protein | Homo sapiens (human) | Potency | 18.1201 | 9 | 23 |
Ataxin-2 | Homo sapiens (human) | Potency | 5.6810 | 1 | 2 |
ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 6.5916 | 2 | 3 |
Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 31.8326 | 1 | 2 |
bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
Caspase-7 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 22.3285 | 3 | 8 |
Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 32.4648 | 1 | 2 |
Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 25.1189 | 1 | 1 |
Chain A, Cruzipain | Trypanosoma cruzi | Potency | 29.9033 | 1 | 2 |
Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 31.6228 | 1 | 1 |
Chain A, HADH2 protein | Homo sapiens (human) | Potency | 28.3708 | 2 | 2 |
Chain B, HADH2 protein | Homo sapiens (human) | Potency | 28.3708 | 2 | 2 |
cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 24.5454 | 1 | 1 |
cytochrome P450 2D6 | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.7717 | 1 | 1 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 17.2912 | 1 | 3 |
DNA polymerase beta | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 33.5875 | 1 | 1 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 23.3056 | 12 | 29 |
estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 44.0954 | 3 | 6 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 11.9769 | 6 | 18 |
euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 36.6603 | 5 | 7 |
G | Vesicular stomatitis virus | Potency | 24.5454 | 1 | 1 |
GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
geminin | Homo sapiens (human) | Potency | 12.7283 | 2 | 3 |
GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.0136 | 3 | 7 |
glp-1 receptor, partial | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 27.1585 | 5 | 12 |
Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 20.3563 | 1 | 3 |
heat shock protein beta-1 | Homo sapiens (human) | Potency | 49.4429 | 2 | 4 |
Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 5.0119 | 1 | 2 |
histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 89.9084 | 2 | 3 |
HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 24.5454 | 1 | 1 |
huntingtin isoform 2 | Homo sapiens (human) | Potency | 12.0627 | 1 | 2 |
hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 37.1431 | 2 | 5 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 16.6115 | 3 | 3 |
Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 24.5454 | 1 | 2 |
Interferon beta | Homo sapiens (human) | Potency | 24.5454 | 1 | 1 |
interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
lamin isoform A-delta10 | Homo sapiens (human) | Potency | 4.3928 | 1 | 2 |
lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 3.1623 | 1 | 1 |
Luciferase | Photinus pyralis (common eastern firefly) | Potency | 62.8512 | 2 | 2 |
Microtubule-associated protein tau | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 0.3162 | 1 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.2792 | 4 | 8 |
nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 56.1231 | 2 | 3 |
Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 4.7308 | 1 | 1 |
nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 24.9115 | 2 | 4 |
nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 26.6627 | 2 | 6 |
peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 18.1056 | 1 | 1 |
peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 19.9580 | 4 | 8 |
Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 26.6514 | 1 | 2 |
peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 35.5018 | 5 | 9 |
polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 1.3516 | 1 | 2 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 57.4570 | 1 | 2 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 20.2967 | 1 | 3 |
pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 70.7946 | 1 | 1 |
progesterone receptor | Homo sapiens (human) | Potency | 16.2182 | 2 | 4 |
RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 6.4962 | 2 | 6 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 29.3500 | 2 | 6 |
retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 20.4264 | 4 | 10 |
SMAD family member 2 | Homo sapiens (human) | Potency | 29.8242 | 2 | 2 |
SMAD family member 3 | Homo sapiens (human) | Potency | 29.8242 | 2 | 2 |
Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 22.9833 | 1 | 2 |
TDP1 protein | Homo sapiens (human) | Potency | 24.2307 | 2 | 2 |
thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 7.4880 | 3 | 7 |
thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 62.0774 | 4 | 8 |
thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 56.0684 | 5 | 5 |
thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 26.6401 | 2 | 3 |
USP1 protein, partial | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 49.0292 | 1 | 2 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 31.0870 | 3 | 5 |
vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 20.3563 | 1 | 3 |