Page last updated: 2024-09-28

Yellow Fever

An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.

Synonyms(1)

Synonym
Yellow Fever

Research Excerpts

Overview

ExcerptReference
"Yellow fever is characterized by hepatocyte damage, with steatosis, apoptosis and necrosis, mainly in the midzonal region of the liver, but the injury mechanism has not been studied at the light of recent knowledge, such as the advances in cell death mechanisms, inflammatory response and cytokine cell expression tools."( Andrade, HF; Barros, VL; Duarte, MI; Fernandes, ER; Guedes, F; Pagliari, C; Quaresma, JA; Takakura, CF; Vasconcelos, PF, 2006)
"Yellow fever is an acute infectious disease caused by prototype virus of the genus Flavivirus."( Caride, E; Freire, MS; Gaspar, LP; Herrera, MA; Matos, DD; Neves, PP; Pereira, RC; Silva, AA; Silva, AN; Silva, MV; Souza, MC; Yamamura, AM, 2015)
"Yellow fever is an acute febrile illness for which there is no specific antiviral treatment."( Alfred Joseph Mayers, N; De Souza Bayão, T; Do Carmo Cupertino, M; Patrícia Gomes, A; Siqueira-Batista, R, 2019)

Treatment

ExcerptReference
"Ribavirin was evaluated as a potential treatment of yellow fever (YF) in a hamster model of the disease."( Guzman, H; Sbrana, E; Tesh, RB; Travassos da Rosa, AP; Xiao, SY; Ye, M, 2004)

Research

Studies (196)

TimeframeStudies, This Condition (%)All Conditions %
pre-199079 (40.31)23.3326
1990's13 (6.63)12.5806
2000's24 (12.24)18.1394
2010's49 (25.00)28.8240
2020's31 (15.82)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetone0low10
adenine0low10
ammonium hydroxide0low10
carbamates0low10
lactic acid0low20
formaldehyde0low10
glycine0low10
glycerol0low10
kynurenine0low10
niacin0low10
triphosphoric acid0low10
pyruvic acid0low10
toluene0low10
urea0low10
1-anilino-8-naphthalenesulfonate0low10
homovanillic acid0low10
hydroxyindoleacetic acid0low10
propiolactone0low20
chloroquine0medium51
cypermethrin0low10
ddt0low50
diphenhydramine0low10
halothane0low10
hydroxyurea0low10
isoniazid0low10
leflunomide0low10
loperamide0low10
malathion0low10
metronidazole0low10
deet0low10
primaquine0low10
3,3',5-triiodothyroacetic acid0low10
thyroxine0low10
prednisone0low20
alanine0low10
aspartic acid0low10
uridine0low10
galactose0low10
adenosine monophosphate0low10
cytidine0low10
chloroform0low10
histidine0low10
tryptophan0low10
pelargonic acid0low10
isoxazoles0low20
pyrazines0low20
2,3-dimethylphenol0low10
2-methylfuran0low130
myristic acid0low10
acetylcysteine0low10
fenchone, (+-)-isomer0low10
zinc oxide0low10
1-octen-3-ol0low20
mannose0low10
ecdysone0low20
mercury0low20
gold0low20
deuterium0low10
3,5-diisopropylsalicylic acid0low30
cetylpyridinium chloride anhydrous0low10
methyl tetradecanoate0low10
4-methoxyamphetamine0low30
transferrin0low10
alkenes0low10
ribavirin0low70
methyldopa0low10
decamethrin0low20
adenosine0low10
glucose, (beta-d)-isomer0low10
chloroquine diphosphate0low10
nsc-1727550low20
fibrinogen0low10
cobaltiprotoporphyrin0low10
dopachrome0low10
small cardioactive peptide b0low10
methotrexate0low20
cortisone0low10
glycogen0low10
cinnamodial0low10
arachidonic acid0low10
favipiravir0low20
2'-c-methylcytidine0low10
sesquiterpenes0low10
dieldrin0low10
quinine0low20
allatostatin 10low10
ovalbumin0low20
galactomannan0low10
myelin basic protein0low10
bilirubin0low10
beta-ocimene0low10
methoprene0low20
ecdysterone0low10
cysteine0low10
radium0low10
fmrfamide0low10
galidesivir0low10
dextrothyroxine0low10
enerbol0low20
clove0low30
acid phosphatase0low10
cytochrome c-t0low10
neuropeptide f0low20
glucagon0low20
oligonucleotides0medium21
cellulose0low10
phosphatidylcholines0low10
chitosan0low10
egg white0low10
mannans0low10
piperidines0low10
sofosbuvir0medium51
heme0low10
heparitin sulfate0low10
tetracycline0low10
transforming growth factor beta0low20
pyrethrins0low60
rome0low10
s 89320low10
exudates0low50
guanosine0low10
neopterin0low20
rifampin0low10
rifapentine0low10
eye0low20
concanavalin a0low10

Protein Targets (876)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase3003
thioredoxin reductase120012
USP1 protein, partial160016
TDP1 protein240024
vitamin D3 receptor isoform VDRA160016
importin subunit beta-1 isoform 15005
flap endonuclease 1100010
serine/threonine-protein kinase PLK15005
snurportin-15005
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
GTP-binding nuclear protein Ran isoform 12002
DNA polymerase eta isoform 14004
DNA polymerase iota isoform a (long)9009
urokinase-type plasminogen activator precursor6006
plasminogen precursor6006
urokinase plasminogen activator surface receptor precursor6006
geminin240024
DNA polymerase kappa isoform 1110011
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0101
Transthyretin0113
Fatty acid-binding protein, intestinal0112
Fatty acid-binding protein, adipocyte0224
Cyclin-A20101
Cannabinoid receptor 10011
Cyclin-dependent kinase 20123
Choline O-acetyltransferase0202
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G2002
Fatty acid-binding protein 50112
Fatty acid-binding protein 50022
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140202
estrogen nuclear receptor alpha400040
cellular tumor antigen p53 isoform a8008
nuclear factor erythroid 2-related factor 2 isoform 1290029
Integrin beta-35005
Integrin alpha-IIb5005
Nuclear receptor ROR-gamma9009
Chain A, Cruzipain8008
hypoxia-inducible factor 1 alpha subunit110011
RAR-related orphan receptor gamma220022
AR protein340034
progesterone receptor180018
estrogen-related nuclear receptor alpha320032
activating transcription factor 6100010
serine-protein kinase ATM isoform a2002
Transient receptor potential cation channel subfamily A member 10011
Rap guanine nucleotide exchange factor 38008
Deoxycytidine kinase0002
Cytidine deaminase0103
RNA-directed RNA polymerase 0024
Chain A, HADH2 protein110011
Chain B, HADH2 protein110011
SMAD family member 26006
SMAD family member 36006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
estrogen receptor 2 (ER beta)120012
nuclear receptor subfamily 1, group I, member 3230023
glucocorticoid receptor [Homo sapiens]210021
retinoid X nuclear receptor alpha220022
farnesoid X nuclear receptor170017
peroxisome proliferator-activated receptor delta160016
peroxisome proliferator activated receptor gamma190019
vitamin D (1,25- dihydroxyvitamin D3) receptor190019
euchromatic histone-lysine N-methyltransferase 2220022
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a120012
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a110011
v-jun sarcoma virus 17 oncogene homolog (avian)190019
cytochrome P450 2C9 precursor3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
thyroid hormone receptor beta isoform 2260026
heat shock protein beta-1140014
DNA polymerase beta4004
survival motor neuron protein isoform d9009
histone acetyltransferase KAT2A isoform 1140014
lamin isoform A-delta10240024
Cellular tumor antigen p53210021
Androgen receptor0101
Thyroid hormone receptor alpha0112
Thyroid hormone receptor beta0112
Proliferating cell nuclear antigen0202
Thyroid hormone receptor beta0101
Retinoic acid receptor RXR-alpha0044
Peroxisome proliferator-activated receptor gamma0044
Histamine H2 receptor7009
Sodium/bile acid cotransporter0101
Solute carrier organic anion transporter family member 1C10101
5-hydroxytryptamine receptor 2C0214
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 1A0213
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0112
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0415
Sodium-dependent serotonin transporter0101
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Chain A, 2-oxoglutarate Oxygenase9009
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
acetylcholinesterase110011
dopamine D1 receptor3003
15-lipoxygenase, partial8008
pregnane X receptor8008
phosphopantetheinyl transferase150015
NFKB1 protein, partial4004
Microtubule-associated protein tau120012
Thrombopoietin5005
regulator of G-protein signaling 48008
retinoic acid nuclear receptor alpha variant 1250025
arylsulfatase A9009
Bloom syndrome protein isoform 19009
D(1A) dopamine receptor1001
thyroid hormone receptor beta isoform a120012
peripheral myelin protein 22100010
muscarinic acetylcholine receptor M17007
Histone deacetylase 30101
Solute carrier family 22 member 60101
Histone deacetylase 40101
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Ataxin-2100010
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
ATP-dependent phosphofructokinase8008
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE140014
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
cytochrome P450 family 3 subfamily A polypeptide 4160016
pregnane X nuclear receptor190019
nuclear factor erythroid 2-related factor 2 isoform 26006
tumor susceptibility gene 101 protein1001
Voltage-dependent calcium channel gamma-2 subunit140014
Bile salt export pump017017
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Glutamate receptor 2140014
Xanthine dehydrogenase/oxidase0202
TAR DNA-binding protein 436006
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 55005
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
NPYLR7B0011
IDH15005
Histone H2A.x130013
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 16006
nuclear receptor ROR-gamma isoform 1100010
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10404
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70022
Sodium/nucleoside cotransporter 20404
Purine nucleoside phosphorylase0203
Epidermal growth factor receptor0202
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30326
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0105
Adenosine receptor A10113
Adenosine receptor A30101
Adenosine receptor A2a0225
Adenosine receptor A2b0012
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0203
Adenosine receptor A10337
Adenosine receptor A2a0113
Adenylate kinase isoenzyme 1 0203
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20404
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10404
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30404
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0102
Fructose-1,6-bisphosphatase 10101
2-dehydropantoate 2-reductase0112
Inosine-5'-monophosphate dehydrogenase0101
Cytochrome P450 2C9 0528
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0101
5'-nucleotidase0001
GTP:AMP phosphotransferase AK3, mitochondrial0001
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 0112
P2Y purinoceptor 110011
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
Chain A, TYROSYL-DNA PHOSPHODIESTERASE150015
Carbonic anhydrase 10005
Carbonic anhydrase 20118
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0003
Glutamate receptor ionotropic, NMDA 1 0417
Proton-coupled amino acid transporter 10202
Adenosine deaminase0001
Carbonic anhydrase 40003
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, Beta-lactamase2002
thioredoxin glutathione reductase4004
aldehyde dehydrogenase 1 family, member A1210021
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
lethal(3)malignant brain tumor-like protein 1 isoform I2002
cytochrome P450 3A4 isoform 1120012
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
caspase-1 isoform alpha precursor3003
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit pi120012
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
Prostaglandin G/H synthase 1 0102
Trypsin0101
Coagulation factor VII0101
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0303
Aromatase0101
Tissue factor0101
Gamma-aminobutyric acid receptor subunit beta-1120012
Gamma-aminobutyric acid receptor subunit delta120012
Gamma-aminobutyric acid receptor subunit gamma-2120012
Gamma-aminobutyric acid receptor subunit alpha-5120012
Gamma-aminobutyric acid receptor subunit alpha-3120012
Gamma-aminobutyric acid receptor subunit gamma-1120012
Gamma-aminobutyric acid receptor subunit alpha-2120012
Gamma-aminobutyric acid receptor subunit alpha-4120012
Gamma-aminobutyric acid receptor subunit gamma-3120012
Gamma-aminobutyric acid receptor subunit alpha-6120012
Prostaglandin G/H synthase 20012
Nuclear receptor subfamily 4 group A member 20022
10 kDa heat shock protein, mitochondrial0303
Calmodulin 0113
Gamma-aminobutyric acid receptor subunit alpha-1120012
Gamma-aminobutyric acid receptor subunit beta-3120012
Gamma-aminobutyric acid receptor subunit beta-2120012
Disintegrin and metalloproteinase domain-containing protein 172002
Prostaglandin G/H synthase 20102
Solute carrier organic anion transporter family member 2A10001
Thiosulfate sulfurtransferase0303
Lanosterol 14-alpha demethylase0303
60 kDa chaperonin 0303
10 kDa chaperonin 0303
GABA theta subunit120012
Gamma-aminobutyric acid receptor subunit epsilon120012
Solute carrier organic anion transporter family member 1B30609
Cytosolic phospholipase A2 gamma0101
Transient receptor potential cation channel subfamily V member 20101
Solute carrier organic anion transporter family member 1B10609
Chain A, Ferritin light chain5005
cytochrome P450 2C19 precursor2002
lethal factor (plasmid)7007
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0316
Glutamate receptor ionotropic, NMDA 2B0316
Glutamate receptor ionotropic, NMDA 2C0316
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0316
Glutamate receptor ionotropic, NMDA 3B0316
Glutamate receptor ionotropic, NMDA 3A0316
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Caspase-72002
Inositol monophosphatase 14004
PPM1D protein4004
Interferon beta120012
Cytochrome P450 1A20506
Cytochrome P450 3A40405
Cytochrome P450 2D60506
Spike glycoprotein71412
Potassium voltage-gated channel subfamily H member 20606
Nonstructural protein 5A 0224
GLI family zinc finger 3200020
caspase 7, apoptosis-related cysteine protease5005
67.9K protein3003
caspase-35005
thyrotropin-releasing hormone receptor3003
Caspase-20011
Luciferase7007
interleukin 85005
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0145
Replicase polyprotein 1ab0145
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20145
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012013
Dihydrofolate reductase 0202
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0203
Histidine-rich protein PFHRP-II0203
Procathepsin L0145
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M40303
Muscarinic acetylcholine receptor M50303
Alpha-2A adrenergic receptor0101
Replicase polyprotein 1a0145
Replicase polyprotein 1ab0145
Replicase polyprotein 1ab0145
Spike glycoprotein0101
Replicase polyprotein 1ab0347
Muscarinic acetylcholine receptor M10303
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
DNA ligase 10101
Muscarinic acetylcholine receptor M30303
Serine/threonine-protein kinase mTOR0101
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0202
Canalicular multispecific organic anion transporter 1012012
Sigma non-opioid intracellular receptor 10303
Angiotensin-converting enzyme 2 0145
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
endonuclease IV5005
GALC protein1001
cytochrome P450 2D68008
potassium voltage-gated channel subfamily H member 2 isoform d8008
PINK11001
thyroid stimulating hormone receptor130013
Parkin2002
bromodomain adjacent to zinc finger domain 2B6006
aryl hydrocarbon receptor110011
thyroid stimulating hormone receptor100010
Caspase-73003
polyunsaturated fatty acid lipoxygenase ALOX124004
prostaglandin E2 receptor EP2 subtype0001
chromobox protein homolog 1150015
caspase-33003
Acetylcholinesterase 0101
Carboxylic ester hydrolase 0101
Rap guanine nucleotide exchange factor 41001
ORF730011
GLS protein8008
peripheral myelin protein 22 isoform 18008
atrial natriuretic peptide receptor 1 precursor1001
M-phase phosphoprotein 87007
Glucocorticoid receptor0415
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10202
G100010
HLA class I histocompatibility antigen, B alpha chain 100010
Inositol hexakisphosphate kinase 1100010
cytochrome P450 2C9, partial100010
EWS/FLI fusion protein100010
Glucose transporter0101
Cdk-related protein kinase 60101
Protein kinase domain-containing protein0101
Hexose transporter 1 0101
Solute carrier family 2, facilitated glucose transporter member 10101
Calcium-dependent protein kinase 10101
Mitogen-activated protein kinase 0101
Proline--tRNA ligase0101
Calcium-dependent protein kinase 40101
Lysine--tRNA ligase 0101
Uridine-cytidine kinase 1 0002
nuclear factor NF-kappa-B p105 subunit isoform 13003
Androgen receptor0303
Chain A, Odorant binding protein0011
Chain B, Odorant binding protein0011
nonstructural protein 13003
glucocerebrosidase1001
neuropeptide S receptor isoform A3003
Fumarate hydratase5005
polyprotein5005
cytochrome P450 2D6 isoform 13003
huntingtin isoform 23003
5-hydroxytryptamine receptor 40202
Aldo-keto reductase family 1 member B10404
Angiotensin-converting enzyme0202
Sodium-dependent noradrenaline transporter 0404
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Histamine H1 receptor0001
Histamine H1 receptor0202
5-hydroxytryptamine receptor 2B0404
Histamine N-methyltransferase0001
Cytochrome P450 2J20101
Sodium channel protein type 5 subunit alpha0202
Solute carrier family 22 member 10304
Nuclear receptor subfamily 3 group C member 3 0202
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0101
Histamine H3 receptor0001
Solute carrier family 22 member 20303
Ultraspiracle0404
20-hydroxy-ecdysone receptor 0404
Ecdysone receptor0202
eyes absent homolog 2 isoform a1001
Ecdysone receptor0101
Protein ultraspiracle0101
Ultraspiracle 0101
20-hydroxy-ecdysone receptor 0101
Ultraspiracle protein 0101
20-hydroxy-ecdysone receptor 0101
Neuropeptide FF receptor 20112
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Purine nucleoside phosphorylase 0101
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10404
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Albumin0123
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Chain A, HISTIDINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
ATAD5 protein, partial5005
Carbonic anhydrase 120002
Plasma kallikrein0002
Carbonic anhydrase 30002
Histidine-binding periplasmic protein0011
Carbonic anhydrase 40103
Carbonic anhydrase 60002
Carbonic anhydrase 5A, mitochondrial0103
Carbonic anhydrase0002
Carbonic anhydrase 70002
Carbonic anhydrase0002
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90104
Carbonic anhydrase 0002
Carbonic anhydrase0002
Carbonic anhydrase0002
Carbonic anhydrase 0002
Carbonic anhydrase 130001
Carbonic anhydrase 150002
Carbonic anhydrase 130002
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
ClpP2002
lysosomal alpha-glucosidase preproprotein3003
Solute carrier family 22 member 80001
Smad32002
hypothetical protein, conserved2002
alpha-galactosidase3003
Uracil nucleotide/cysteinyl leukotriene receptor0202
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10213
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0202
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0202
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20202
Bile salt export pump0606
Myeloperoxidase0202
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Cytochrome P450 2C190101
Endonuclease III-like protein 10101
DNA gyrase subunit B0202
DNA gyrase subunit A0202
Enoyl-[acyl-carrier-protein] reductase [NADH]0203
Pantothenate synthetase0101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
glp-1 receptor, partial3003
matrix metalloproteinase 1, partial0011
P531001
pyruvate kinase2002
nuclear receptor subfamily 1, group I, member 21001
NPC intracellular cholesterol transporter 1 precursor1001
histone deacetylase 9 isoform 31001
ras-related protein Rab-9A2002
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Amine oxidase [flavin-containing] A0202
Endothelin receptor type B1001
Endothelin-1 receptor1001
Sodium-dependent dopamine transporter 0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Protein-arginine deiminase type-40303
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 12002
Menin0101
Cocaine esterase0202
Solute carrier family 22 member 1 0303
Beta-2 adrenergic receptor0202
ATP-dependent translocase ABCB10305
D(2) dopamine receptor0101
D(4) dopamine receptor0101
Histamine H2 receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Delta-type opioid receptor0213
Kappa-type opioid receptor0202
Nociceptin receptor0101
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 70202
Mu-type opioid receptor0011
Angiopoietin-1 receptor0011
Carboxylic ester hydrolase 0101
transcriptional regulator ERG isoform 32002
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Thymidylate synthase 0101
Thymidylate synthase 0101
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
muscleblind-like protein 1 isoform 13003
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30002
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80002
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110002
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Caspase 6, apoptosis-related cysteine peptidase0001
apical membrane antigen 1, AMA12002
estrogen receptor beta isoform 10202
Tyrosine-protein kinase Fyn0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
Cystathionine gamma-lyase0101
Solute carrier family 15 member 10101
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Toll-like receptor 20101
Peroxisome proliferator-activated receptor delta0001
Dynamin-10101
Peroxisome proliferator-activated receptor alpha1012
G-protein coupled receptor 840123
Neuronal acetylcholine receptor subunit alpha-41001
Cholesteryl ester transfer protein0101
Neuronal acetylcholine receptor subunit beta-21001
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
90-kda heat shock protein beta HSP90 beta, partial0202
heat shock protein HSP 90-alpha isoform 20202
Acetylcholinesterase0102
Amine oxidase [flavin-containing] B0101
Serine hydroxymethyltransferase, mitochondrial0101
Chloroquine resistance transporter0101
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Prolyl 4-hydroxylase0101
Solute carrier organic anion transporter family member 2A10101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Solute carrier family 22 member 10101
Solute carrier family 22 member 20102
Solute carrier organic anion transporter family member 1A40203
Solute carrier family 22 member 20101
Potassium channel subfamily K member 20101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Solute carrier organic anion transporter family member 1A10202
Cytochrome P450 2D40101
NS5 0123
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosine receptor A10101
Genome polyprotein0011
DNA-directed RNA polymerase subunit beta0101
Nuclear receptor subfamily 1 group I member 20022
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0202
Solute carrier organic anion transporter family member 1A20102
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Cereblon isoform 40101
Protein cereblon0303
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
polyadenylate-binding protein 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Alpha-1B adrenergic receptor0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Alpha-1A adrenergic receptor0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Solute carrier family 22 member 70001
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Solute carrier organic anion transporter family member 1A50001
UDP-glucuronosyltransferase 1A1 0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Endolysin0011
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
SLC16A10 protein0001
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
Chain A, Cytidine Deaminase0101
Chain A, Arginase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]