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glycine derivative

A proteinogenic amino acid derivative resulting from reaction of glycine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.

ChEBI ID: 24373

Members (17)

MemberDefinitionRole
(n-(p-cyanophenyl)-n'-(diphenylmethyl)guanidine)acetic acidA trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent.[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid
5-(carboxymethylaminomethyl)-2-thiouridineA thiouridine that is 2-thiouridine bearing an additional carboxymethylaminomethyl substituent at position 5 on the thiouracil ring.5-carboxymethylaminomethyl-2-thiouridine
betaineThe amino acid betaine derived from glycine.glycine betaine
creatineA glycine derivative having methyl and amidino groups attached to the nitrogen.creatine zwitterion; creatine
dimethyloxalylglycineA glycine derivative that is the diester obtained by formal condensation of the carboxy groups of N-oxalylglycine with two molecules of methanol.dimethyloxalylglycine
eddaAn ethylenediamine derivative in which two of the four amine protons of ethylenediamine are replaced by carboxymethyl groups.ethylenediaminediacetic acid
fructosyl-glycinefructosylglycine
glycine amideglycinamide
glyphosateA phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).glyphosate
glyphosphineA tertiary amino compound that consists of glycine bearing two N-phosphonomethyl substituents.glyphosine
iminodiacetic acidAn amino dicarboxylic acid that is glycine in which one of the hydrogens attached to the nitrogen is substituted by a carboxymethyl group.iminodiacetic acid
ixazomibA glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma.ixazomib
methyl hippurateA glycine derivative that is the methyl ester of hippuric acid.methyl hippurate
N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamideAn amino acid amide obtained by the formal condensation of 2,6-dimethylaniline with N-(3,5-dimethylphenyl)glycine.N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamide
N(2)-carbamimidoyl-N-{2-[4-(3-{4-[(5-carboxyfuran-2-yl)methoxy]-2,3-dichlorophenyl}-1-methyl-1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoethyl}-D-leucinamideA leucine derivative obtained by fpormal condensation of the secondary amino group of 5-({2,3-dichloro-4-[1-methyl-5-(piperidin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)-2-furoic acid and the carboxy group of N-amidino-L-leucylglycineN(2)-carbamimidoyl-N-{2-[4-(3-{4-[(5-carboxyfuran-2-yl)methoxy]-2,3-dichlorophenyl}-1-methyl-1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoethyl}-D-leucinamide
osu 03012A member of the class of pyrazoles that is N-[4-(pyrazol-1-yl)phenyl]glycinamide in which the pyrazole ring is substituted at positions 3 and 5 by trifluoromethyl and phenanthrene-2-yl groups respectively.OSU-03012
vinylglycineA non-proteinogenic L-alpha-amino acid with a structure in which a vinyl group is bonded to the alpha-carbon of glycine.L-vinylglycine zwitterion; L-vinylglycine

Research

Studies (19,328)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,998 (20.69)18.7374
1990's2,194 (11.35)18.2507
2000's4,535 (23.46)29.6817
2010's5,910 (30.58)24.3611
2020's2,691 (13.92)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,275 (6.27%)5.53%
Reviews1,252 (6.16%)6.00%
Case Studies794 (3.91%)4.05%
Observational75 (0.37%)0.25%
Other16,929 (83.29%)84.16%