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6-(dimethylamino)-4,4-diphenylheptan-3-one

A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

ChEBI ID: 167309

Members (2)

MemberDefinitionRole
dextromethadoneA 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder.dextromethadone
levomethadoneA 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (R)-configuration. It is the active enantiomer of methadone and its hydrochloride salt is used to treat adults who are addicted to drugs such as heroin and morphine.levomethadone

Research

Studies (10)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903 (30.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's2 (20.00)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials3 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (80.00%)84.16%