Page last updated: 2024-08-05 11:19:10

N-sulfonyldiazepane

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ChEBI ID: 46946

Members (3)

MemberDefinitionRole
fasudilAn isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.fasudil
h 1152A member of the class of isoquinolines that is the sulfonamide formed by the formal condensation of the sulfo group of 4-methylisoquinoline-5-sulfonic acid with the 1-amino group of (S)-2-methyl-1,4-diazepane.(S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane
ml 7An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).ML-7

Research

Studies (1,193)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19906 (0.50)18.7374
1990's80 (6.71)18.2507
2000's411 (34.45)29.6817
2010's577 (48.37)24.3611
2020's119 (9.97)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials40 (3.24%)5.53%
Reviews73 (5.92%)6.00%
Case Studies9 (0.73%)4.05%
Observational1 (0.08%)0.25%
Other1,110 (90.02%)84.16%