tetracycline and Rheumatic-Heart-Disease

A retrospective study was done on patients admitted to the University of Michigan Hospital from 1962 to 1972 with a diagnosis of bacterial endocarditis. The findings in the group studied indicate that Streptococcus viridans was the predominant causative organism, males were affected three times as often as females, erythromycin was effective against organisms of oral origin, dental procedures were not definitely established as responsible for the onset of the disease in any of the cases, and rheumatic heart disease and congenital heart disease were the predominant, but not the only, predisposing factors.

Topics: Age Factors; Dental Care; Endocarditis, Bacterial; Erythromycin; Heart Defects, Congenital; Heroin Dependence; Humans; Microbial Sensitivity Tests; Mouth; Penicillins; Retrospective Studies; Rheumatic Heart Disease; Sex Factors; Streptococcus; Streptomycin; Tetracycline; Tooth

Topics: Administration, Oral; Bacteriological Techniques; Endocarditis, Bacterial; Erythromycin; Gingiva; Humans; Injections, Intramuscular; Lincomycin; Long-Term Care; Microbial Sensitivity Tests; Penicillin G; Penicillin G Benzathine; Penicillin Resistance; Rheumatic Fever; Rheumatic Heart Disease; Staphylococcus; Streptococcus; Sulfadiazine; Tetracycline

Topics: Adult; Aged; Anti-Bacterial Agents; Chloramphenicol; Dysentery, Bacillary; Enterocolitis, Pseudomembranous; Erythromycin; Humans; Intestines; Male; Middle Aged; Nalidixic Acid; Nystatin; Penicillins; Pneumonia; Proteus Infections; Rheumatic Heart Disease; Staphylococcal Infections; Streptomycin; Tetracycline

Topics: Adrenocorticotropic Hormone; Cardiomegaly; Convalescence; Digitalis Glycosides; Diuretics; Endocarditis, Bacterial; Erythromycin; Glucocorticoids; Heart Failure; Humans; Injections, Intramuscular; Penicillins; Pericarditis; Rheumatic Heart Disease; Socioeconomic Factors; Streptococcal Infections; Tetracycline

Topics: Endocarditis; Humans; Male; Middle Aged; Mitral Valve; Mitral Valve Stenosis; Penicillins; Q Fever; Rheumatic Heart Disease; Rickettsia; Serologic Tests; Tetracycline

Topics: Animals; Characidae; Heart; Humans; Rheumatic Heart Disease; Tetracycline; Vaccines