Classes > monobactam
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monobactam

Monocyclic, bacterially produced or semisynthetic beta-lactam antibiotic. It lacks the double ring construction of the traditional beta-lactam antibiotics and can be easily synthesized.

ChEBI ID: 50695

Members (10)

MemberDefinitionRole
1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
2-[[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid2-[[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
3-(4-chlorophenoxy)-4-[(3-methoxypropylamino)methyl]-1-(2-methylphenyl)-2-azetidinone3-(4-chlorophenoxy)-4-[(3-methoxypropylamino)methyl]-1-(2-methylphenyl)-2-azetidinone
4-[1-[2-(3,4-dimethoxyphenyl)ethyl]-3-(4-methoxyphenoxy)-4-oxo-2-azetidinyl]benzoic acid methyl ester4-[1-[2-(3,4-dimethoxyphenyl)ethyl]-3-(4-methoxyphenoxy)-4-oxo-2-azetidinyl]benzoic acid methyl ester
aztreonamA synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.aztreonam
carumonamAn N-sulfonated monobactam antibiotic.carumonam
sq 26180SQ 26180
tabtoxinA monobactam phytotoxic dipeptide produced by Pseudomonas syringae, that causes wildfire disease in tobacco.tabtoxin
tabtoxinine beta-lactamtabtoxinine beta-lactam
tigemonamtigemonam

Research

Studies (361)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199099 (27.42)18.7374
1990's24 (6.65)18.2507
2000's132 (36.57)29.6817
2010's94 (26.04)24.3611
2020's12 (3.32)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials11 (2.81%)5.53%
Reviews9 (2.30%)6.00%
Case Studies5 (1.28%)4.05%
Observational0 (0.00%)0.25%
Other366 (93.61%)84.16%