A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
| Member | Definition | Role |
|---|
| 1,3-butylene glycol | A butanediol compound having two hydroxy groups in the 1- and 3-positions. | butane-1,3-diol |
| 1,4-butanediol | A butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16degreeC) with a high boiling point (230degreeC), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). | butane-1,4-diol |
| 2,3-butylene glycol | A butanediol in which hydroxylation is at C-2 and C-3. | butane-2,3-diol |
| 2,5-hexanediol | A glycol that is hexane substituted by hydroxy groups at positions 2 and 5. | hexane-2,5-diol |
| 3-phenylamino-1,2-propanediol | A glycol that is a derivative of glycerol in which one of the hydroxy groups is replaced by an anilino group. | PAP |
| chlorphenesin | Glycerol in which the hydrogen of one of the primary hydroxy groups is substituted by a 4-chlorophenyl group. It has antifungal and antibacterial properties, and is used for treatment of cutaneous and vaginal infections. Its 1-carbamate is used as a skeletal muscle relaxant for the treatment of painful muscle spasm. | chlorphenesin |
| decane-1,2-diol | A glycol that is decane bearing two hydroxy substituents located at positions 1 and 2. | decane-1,2-diol |
| dihydrocubebin | A glycol that is butane-1,4-diol substituted at the 2- and 3-positions by (1,3-benzodioxol-5-yl)methyl groups (the R,R-configuration). | dihydrocubebin |
| dithiothreitol | A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group. | 1,4-dimercaptobutane-2,3-diol; 1,4-dithiothreitol |
| ethylene glycol | A 1,2-glycol compound produced via reaction of ethylene oxide with water. | ethylene glycol |
| glafenine | A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market. | glafenine |
| hexylene glycol | A glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane). | 2-methylpentane-2,4-diol |
| pinacol | A glycol that is ethylene glycol in which all four methylene hydrogens have been replaced by methyl groups. | pinacol |
| propylene glycol | The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze. | propane-1,2-diol |