tetracycline and Bronchial-Fistula

The results of treatment of 226 patients with unspecific spontaneous pneumothorax in 1980-1990 are discussed. Poor efficacy of punctures of the pleural cavity (32.4%) is noted. Pleural cavity drainage proved to be effective in 79.7% of cases, both in primary and in recurrent pneumothorax. Chemical pleurodesis with tetracycline and 4% sodium bicarbonate solution was conducted in patients with complicated forms of pneumothorax (bronchopleural fistulas, hydropneumothorax). The advantage of 4% sodium bicarbonate solution over the tetracycline solution was obvious. To prevent the development of encapsulated hydrothorax the authors improved the method of pleural cavity drainage. The described method of instrumental treatment of spontaneous pneumothorax allowed injurious surgical intervention and recurrent pneumothorax to be avoided in 100% of cases.

Topics: Adult; Animals; Bronchial Fistula; Combined Modality Therapy; Drainage; Female; Fistula; Humans; Hydropneumothorax; Male; Middle Aged; Pleural Diseases; Pneumothorax; Punctures; Rats; Recurrence; Sodium Bicarbonate; Tetracycline

Topics: AIDS-Related Opportunistic Infections; Bronchial Fistula; Chest Tubes; Doxycycline; Humans; Male; Pleura; Pleural Diseases; Pneumonia, Pneumocystis; Tetracycline

Topics: Bronchial Fistula; Doxycycline; Embolization, Therapeutic; Fistula; Humans; Pleural Diseases; Tetracycline

Persistent bronchopleural fistulas (BPF) due to infection, trauma, or thoracic surgical procedures are often difficult to manage. We report a patient with fulminant Staphylococcus aureus pneumonia complicated by chronic BPF formation which prevented weaning from mechanical ventilation due to severe air leak. Fistula closure was obtained by instillation of tetracycline into the fistula via a fiberoptic bronchoscope using a balloon catheter and blood clot occlusion technique. This closed the BPF and allowed successful weaning from mechanical ventilation.

Topics: Adolescent; Bronchial Fistula; Bronchoscopy; Fistula; Humans; Instillation, Drug; Male; Pleural Diseases; Pneumonia, Staphylococcal; Sclerotherapy; Tetracycline

Topics: Abscess; Anti-Bacterial Agents; Bacitracin; Bronchial Fistula; Chloramphenicol; Empyema; Erythromycin; Humans; Kanamycin; Novobiocin; Penicillins; Pleural Effusion; Pneumonia; Pneumonia, Staphylococcal; Pneumothorax; Sepsis; Staphylococcal Infections; Tetracycline; Vancomycin

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bronchial Fistula; Bronchopneumonia; Cross Infection; Empyema; Humans; Influenza, Human; Lung Abscess; Pneumonectomy; Postoperative Complications; Sputum; Staphylococcal Infections; Surgical Wound Infection; Tetracycline; Thoracic Diseases; Thoracoplasty; Tuberculosis; Tuberculosis, Pulmonary

Topics: Anti-Bacterial Agents; Bronchial Fistula; Chloramphenicol; Chlortetracycline; Collapse Therapy; Drug Therapy; Empyema; Escherichia coli Infections; Humans; Klebsiella; Penicillins; Pneumonectomy; Polymyxins; Postoperative Complications; Staphylococcal Infections; Streptomycin; Tetracycline; Thoracic Surgery