Page last updated: 2024-08-05 11:32:29

3alpha-hydroxy steroid

A 3-hydroxy steroid in which the 3-hydroxy substituent is in the alpha-position.

ChEBI ID: 36835

Members (24)

MemberDefinitionRole
3 alpha,17 alpha-dihydroxy-5 beta-pregnan-20-oneA 17alpha-hydroxy steroid that is 3alpha-hydroxy-5beta-pregnan-20-one carrying an additional hydroxy group at position 17alpha.3alpha,17alpha-dihydroxy-5beta-pregnan-20-one
3,7,12-trihydroxycholestan-26-oic acidA steroid acid that is 5beta-cholestan-26-oic acid which is substituted by hydroxy groups as the 3alpha, 7alpha, and 12alpha positions.3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid
3,7,12-trihydroxycoprostane5beta-cholestane-3alpha,7alpha,12alpha-triol
3,7,12-trihydroxycoprostanic acid3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane-5-carboxylic acid
3,7,12,24-tetrahydroxycholestanoic acid3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oic acid
3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a hydroxy group at position 3, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic, anticholinergic and antiserotonergic activities.zhankuic acid B
3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by hydroxy groups at positions 3 and 12, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha,12alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits antineoplastic activity.zhankuic acid C
7-ketolithocholic acidA bile acid that is lithocholic acid carrying an additional oxo substituent at position 7.7-oxolithocholic acid
allocholic acidAn allo-bile acid that is 5alpha-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.allocholic acid
androsteroneAn androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone .androsterone
brassinolidebrassinolide
castasteronecastasterone
cholestane-3,7,12,26-tetrol5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol
cholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.cholic acid
dihydroxycoprostane5beta-cholestane-3alpha,7alpha-diol
etiocholanoloneAn androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.3alpha-hydroxy-5beta-androstan-17-one
fusidic acidA steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum.fusidic acid
muricholic acidA group of trihydroxy-5beta-cholanic acids that are the 6,7-diastereoisomers of 3alpha,6,7-trihydroxy-5beta-cholan-24-oic acid.muricholic acids
obeticholic acidA dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.obeticholic acid
pregnanoloneThe 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.3alpha-hydroxy-5beta-pregnan-20-one
rocuroniumA 5alpha-androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents.rocuronium
scymnol5beta-scymnol
tetrahydrocortisoltetrahydrocortisol
ursocholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three hydroxy substituents at positions 3alpha, 7beta and 12alpha.ursocholic acid

Research

Studies (11,308)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,351 (29.63)18.7374
1990's1,700 (15.03)18.2507
2000's2,399 (21.22)29.6817
2010's2,887 (25.53)24.3611
2020's971 (8.59)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,171 (9.16%)5.53%
Reviews722 (5.65%)6.00%
Case Studies706 (5.52%)4.05%
Observational72 (0.56%)0.25%
Other10,114 (79.11%)84.16%