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dihydroxyflavanone

Any hydroxyflavanone carrying two hydroxy substituents.

ChEBI ID: 38749

Members (15)

MemberDefinitionRole
(2S)-5,7-dihydroxy-6,8-dimethylflavanoneA dihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5 and 7 and methyl groups at positions 6 and 8. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.(2S)-5,7-dihydroxy-6,8-dimethylflavanone
2'-methoxykurarinoneA dimethoxyflavanone that is (2S)-(-)-kurarinone in which the hydroxy group at position 2' is replaced by a methoxy group. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells.(2S)-2'-methoxykurarinone
4',7-dihydroxyflavanoneA dihydroxyflavanone in which the two hydroxy substituents are located at positions 4' and 7.4',7-dihydroxyflavanone
7,8-dihydroxyflavanoneA dihydroxyflavanone with hydroxy substituents at positions 7 and 8. Isolated from the seeds of Alpinia katsumadai, it acts as a an inhibitor for Jun-Fos-DNA complex formation and exhibits antineoplastic activity.7,8-dihydroxyflavanone
diosminA disaccharide derivative that consists of diosmetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.diosmin
glabraninA dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8.glabranin
hesperidinA disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.hesperidin
isonaringinA disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.narirutin
isosakuranetinA dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 4' (the 2S stereoisomer).4'-methoxy-5,7-dihydroxyflavanone
matteucinolA dihydroxyflavanone that is (2S)-flavanone with hydroxy groups at positions 5 and 7, methyl groups at positions 6 and 8 and a methoxy group at position 4'.matteucinol
naringinA disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.naringin
pinocembrinA dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.pinocembrin
prunin protein, prunusA flavanone 7-O-beta-D-glucoside that is (S)-naringenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.naringenin 7-O-beta-D-glucoside
sakuranetinA flavonoid phytoalexin that is (S)-naringenin in which the hydroxy group at position 7 is replaced by a methoxy group.sakuranetin
sophoranoneA dihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7 and 4' and prenyl groups at positions 3' and 5' respectively.sophoranone

Research

Studies (3,325)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990168 (5.05)18.7374
1990's196 (5.89)18.2507
2000's570 (17.14)29.6817
2010's1,574 (47.34)24.3611
2020's817 (24.57)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials253 (6.57%)5.53%
Reviews198 (5.15%)6.00%
Case Studies18 (0.47%)4.05%
Observational13 (0.34%)0.25%
Other3,366 (87.47%)84.16%