Page last updated: 2024-08-05 11:02:48

propanolamine

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ChEBI ID: 35533

Members (10)

MemberDefinitionRole
3-amino-1-propanolA member of the class of propanolamines that is propane with a hydroxy substituent at C-1 and an amino substituent at C-2, making it both a primary amine and a primary alcohol.3-aminopropan-1-ol
acebutololAn ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.acebutolol
atenololAn ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.atenolol
betaxololA propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective beta1-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure.betaxolol
bevantololA propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by 3-methylphenyl and one of the hydrogens attached to the nitrogen is substituted by 2-(3,4-dimethoxyphenyl)ethyl. A beta1 adrenoceptor antagonist, it has been shown to be as effective as other beta-blockers for the treatment of angina pectoris and hypertension.bevantolol
levobunololA cyclic ketone that is 3,4-dihydronaphthalen-1-one substituted at position 5 by a 3-(tert-butylamino)-2-hydroxypropoxy group (the S-enantiomer). A non-selective beta-adrenergic antagonist used (as its hydrochloride salt) for treatment of glaucoma.levobunolol
metipranolol3-(Propan-2-ylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by a 4-acetoxy-2,3,5-trimethylphenoxy group. A non-cardioselective beta-blocker, it is used to lower intra-ocular pressure in the management of open-angle glaucoma.metipranolol
metoprololA propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.metoprolol
practololN-(4-Hydroxyphenyl)acetamide in which the hydrogen of the phenolic hydroxy group is substituted by a 3-(isopropylaminoamino)-2-hydroxypropyl group. A selective beta blocker, it has been used in the emergency treatment of cardiac arrhythmias.practolol
propranololA propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.propranolol

Research

Studies (41,896)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199024,337 (58.09)18.7374
1990's6,996 (16.70)18.2507
2000's4,895 (11.68)29.6817
2010's4,533 (10.82)24.3611
2020's1,135 (2.71)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials7,929 (16.39%)5.53%
Reviews1,984 (4.10%)6.00%
Case Studies3,025 (6.25%)4.05%
Observational58 (0.12%)0.25%
Other35,393 (73.14%)84.16%