A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
| Member | Definition | Class |
|---|
| 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone | An enone with a trimethylcyclohexenyl substituent at C-1. | 1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-enone |
| 1,2-dibromo-2,4-dicyanobutane | An organobromine compound that consists of pentanedinitrile bearing bromo and bromomethyl substituents at position 2. | 2-bromo-2-(bromomethyl)pentanedinitrile |
| 1,3-dibutyl-2-thiourea | Thiourea in which each nitrogen carries a butyl substituent. | N,N'-dibutylthiourea |
| 1,6-hexamethylene diisocyanate | A diisocyanate compound with the two isocyanates linked by a hexane-1,6-diyl group. | hexamethylene diisocyanate |
| 2-thiopyridine | Pyridine substituted at C-2 by a sulfanyl group. | pyridine-2-thiol |
| 2,4-dinitrophenol | A dinitrophenol having the nitro groups at the 2- and 4-positions. | 2,4-dinitrophenol |
| 2,5-diaminotoluene | A diamine in which the two amino groups are substituted into toluene at the 2- and 5-positions. | 2-methyl-1,4-phenylenediamine |
| 2,6-diisocyanatotoluene | A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 6 relative to the methyl group on the benzene ring. | toluene 2,6-diisocyanate |
| 3-pentadecacatechol | Catechol substituted at position 3 with a pentadecyl group. | 3-pentadecylcatechol |
| 4-aminobenzoic acid | An aminobenzoic acid in which the amino group is para to the carboxy group. | 4-aminobenzoic acid; 4-ammoniobenzoate |
| 4-aminodiphenylamine | An aromatic amine that is the 4-amino derivative of diphenylamine. | p-aminodiphenylamine |
| 4-aminophenol | An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group. | 4-aminophenol |
| 4-nitrobenzyl bromide | A C-nitro compound that consists of nitrobenzene bearing a bromomethyl substituent at the para-position. | 4-nitrobenzyl bromide |
| 4-nitrososulfamethoxazole | A sulfonamide compound having a 4-nitrosophenyl group attached to the sulfur atom and a 1,2-oxazol-3-yl group attached to the nitrogen atom. | nitrososulfamethoxazole |
| 4-phenylenediamine | A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus. | 1,4-phenylenediamine |
| 4-sulfanilic acid | An aminobenzenesulfonic acid that is aniline sulfonated at the para-position. | 4-aminobenzenesulfonic acid |
| 4-tolyl isocyanate | An isocyanate comprising a benzene core with isocyanato and methyl substituents para to each other. | 4-tolyl isocyanate |
| 4,4'-diaminodiphenylmethane | An aromatic amine that is diphenylmethane substituted at the 4-position of each benzene ring by an amino group. | 4,4'-diaminodiphenylmethane |
| 4,4'-diphenylmethane diisocyanate | A diisocyanate consisting of diphenylmethane with two isocyanate groups at the 4- and 4'-positions. | diphenylmethane-4,4'-diisocyanate |
| 4'-hydroxydiclofenac | A monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac. | 4'-hydroxydiclofenac |
| 5-hydroxydiclofenac | A monocarboxylic acid that is the 5-hydroxylated metabolite of diclofenac. | 5-hydroxydiclofenac |
| 6-methylcoumarin | A member of the class of coumarins that is coumarin in which the hydrogen at position 6 is replaced by a methyl group. | 6-methylcoumarin |
| 6-tuliposide a | A 6-O-acyl-D-glucose that is the 6-O-(4-hydroxy-2-methylenebutanoyl) derivative of D-glucopyranose. | 6-tuliposide A |
| aminopenicillanic acid | A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics. | 6-aminopenicillanic acid zwitterion; 6-aminopenicillanic acid |
| anthrarobin | An anthracenetriol having the three hydroxy substituents at the 1-, 2- and 10-positions. | anthrarobin |
| barbituric acid | A barbiturate, the structure of which is that of perhydropyrimidine substituted at C-2, -4 and -6 by oxo groups. Barbituric acid is the parent compound of barbiturate drugs, although it is not itself pharmacologically active. | barbituric acid |
| benzocaine | A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina. | benzocaine |
| benzylamine | A primary amine compound having benzyl as the N-substituent. It has been isolated from Moringa oleifera (horseradish tree). | benzylamine |
| beryllium sulfate | A metal sulfate in which the metal is beryllium (in the +2 oxidation state) and the ratio of beryllium to sulfate is 1:1. | beryllium sulfate |
| beta-aminoarteether maleate | The maleate salt of beta-aminoarteether. Synthetic artemisinin derivative with potent immunosuppressive activity. | beta-aminoarteether maleate |
| bis(diphenylphosphine)ethane | | 1,2-bis(diphenylphosphino)ethane |
| butyl isocyanate | An isocyanate having a butyl group attached to the nitrogen. | n-butyl isocyanate |
| butylphen | A member of the class of phenols that is phenol substituted with a tert-butyl group at position 4. | 4-tert-butylphenol |
| carbamazepine epoxide | An epoxide and metabolite of carbamazepine. | carbamazepine-10,11-epoxide |
| carvone | A p-menthane monoterpenoid that consists of cyclohex-2-enone having methyl and isopropenyl substituents at positions 2 and 5, respectively. | carvone |
| chloramine-t | An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen. | chloramine T |
| choline | A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. | choline |
| cobaltous chloride | A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants. | cobalt dichloride |
| cyclohexylisocyanate | An isocyanate comprising a cyclohexane core with a single isocyanato substituent. | cyclohexyl isocyanate |
| dehydroabietic acid | An abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group. | dehydroabietic acid |
| dibenzothiazyl disulfide | An organic disulfide resulting from the formal oxidative coupling of the thiol groups of two molecules of 1,3-benzothiazole-2-thiol. It is used as an accelerator in the rubber industry. | dibenzothiazol-2-yl disulfide |
| dimethoxyphenylethylamine | An aromatic ether that is the derivative of 2-phenylethylamine with methoxy substituents at the 3- and 4-positions. It is an alkaloid isolated from the Cactaceae family. | 3,4-dimethoxyphenylethylamine |
| dinitrochlorobenzene | A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions. | 1-chloro-2,4-dinitrobenzene |
| dinitrofluorobenzene | The organofluorine compound that is benzene with a fluoro substituent at the 1-position and two nitro substituents in the 2- and 4-positions. | 1-fluoro-2,4-dinitrobenzene |
| diphenylguanidine | Guanidine carrying a phenyl substituent on each of the two amino groups. It is used as an accelerator in the rubber industry. | 1,3-diphenylguanidine |
| diphenylthiourea | Thiourea in which each nitrogen carries a phenyl substituent. | N,N'-diphenylthiourea |
| disperse blue 124 | A monoazo compound consisting of diazene with a 5-nitrothiazol-2-yl group attached to one nitrogen and a substituted 4-aminophenyl group attached to the other; used as a dye standard for the assay of allergy-releasing dyes in textiles. | Disperse Blue 124 |
| disperse orange 3 | Azobenzene substituted at the phenyl 4-positions by an amino and a nitro group. | 4-(4-nitrophenylazo)aniline |
| ethyl isothiocyanate | An isothiocyanate having an ethyl group attached to the nitrogen. | ethyl isothiocyanate |
| ethylene dimethacrylate | The enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol. | ethylene glycol dimethacrylate |
| ethylene oxide | A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. | oxirane |
| fluazinam | A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. | fluazinam |
| formaldehyde | An aldehyde resulting from the formal oxidation of methanol. | formaldehyde |
| framycetin | A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. | framycetin |
| geraniol | A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end. | geraniol |
| glyceryl monothioglycolate | A thioglycolate ester resulting from esterification of thioglycolic acid with glycerol. As a component of developer solutions in permanent wave products, it is the second most frequent allergen in hairdressers and avoidance of acid permanent waves is mandatory. | glyceryl monothioglycolate |
| glyoxal | The dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons. | glyoxal |
| hydroxycitronellal | The tertiary alcohol arising from addition of water across the C=C double bond of citronellal. | hydroxycitronellal |
| hydroxyethyl methacrylate | An enoate ester that is the monomethacryloyl derivative of ethylene glycol. | 2-hydroxyethyl methacrylate |
| krn 7000 | A glycophytoceramide having an alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen. | 1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine |
| lamivudine | A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. | lamivudine |
| maleic anhydride | A cyclic dicarboxylic anhydride that is the cyclic anhydride of maleic acid. | maleic anhydride |
| mannitol | The D-enantiomer of mannitol. | D-mannitol |
| methyl isocyanate | The isocyanate that is methane modified by a single isocyanato substituent. | methyl isocyanate |
| methylene bis(4-cyclohexylisocyanate) | A diisocyanate consisting of dicyclohexylmethane with two isocyanate groups at the 4- and 4'-positions. | dicyclohexylmethane-4,4'-diisocyanate |
| methylmethacrylate | An enoate ester having methacrylic acid as the carboxylic acid component and methanol as the alcohol component. | methyl methacrylate |
| monobenzone | The monobenzyl ether of hydroquinone. It is used as a topical drug for medical depigmentation. | monobenzone |
| n-isopropyl-n-phenyl-4-phenylenediamine | The N-substituted diamine that is 1,4-phenylenediamine substituted at one N with an isopropyl group and at the other with a phenyl group. | N-isopropyl-N'-phenyl-p-phenylenediamine |
| n-methyl-4-aminophenol | The phenol that is the N-methyl derivative of 4-aminophenol. | 4-methylaminophenol |
| n-phenylglycine | A glycine carrying an N-phenyl substituent. | N-phenylglycine |
| nickel sulfate | A metal sulfate having nickel(2+) as the metal ion. | nickel sulfate |
| phenoxyacetic acid | A monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes. | phenoxyacetic acid |
| phenyl isocyanate | An isocyanate composed of a benzene ring bearing a single isocyanato substituent. | phenyl isocyanate |
| phenylacetic acid | A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group. | phenylacetic acid |
| phenylisothiocyanate | An isothiocyanate having a phenyl group attached to the nitrogen; used for amino acid sequencing in the Edman degradation. | phenyl isothiocyanate |
| phosphorylcholine | The phosphate of choline; and the parent compound of the phosphocholine family. | phosphocholine |
| phthalic anhydride | The cyclic dicarboxylic anhydride that is the anhydride of phthalic acid. | phthalic anhydride |
| picryl chloride | The C-nitro compound that is chlorobenzene with three nitro substituents in the 2-, 4- and 6-positions. | 1-chloro-2,4,6-trinitrobenzene |
| potassium dichromate | A potassium salt that is the dipotassium salt of dichromic acid. | potassium dichromate |
| primin | A 1,4-benzoquinone having a methoxy substituent at the 2-position and a pentyl substituent at the 6-position. | primin |
| propylene glycol | The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze. | propane-1,2-diol |
| pyrimidine-2-thiol | Pyrimidine substituted at C-2 by a sulfanyl group. | pyrimidine-2-thiol |
| resorcinol monobenzoate | A benzoate ester resulting from the formal condensation of benzoic acid with resorcinol. | resorcinol monobenzoate |
| sodium bisulfite | An inorganic sodium salt having hydrogensulfite as the counterion. | sodium hydrogensulfite |
| squaric acid dibutyl ester | A cyclic ketone and diether that is a dibutyl ether derivative of squaric acid. | squaric acid dibutyl ester |
| sulfamethoxazole hydroxylamine | A sulfonamide compound having a 4-hydroxylaminophenyl group attached to the sulfur atom and a 1,2-oxazol-3-yl group attached to the nitrogen atom. | sulfamethoxazole hydroxylamine |
| tetrachlorophthalic anhydride | A cyclic dicarboxylic anhydride that is phthalic anhydride chlorinated at the 4-, 5-, 6- and 7-positions. | tetrachlorophthalic anhydride |
| thiobarbituric acid | A barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur. | 2-thiobarbituric acid |
| tixocortol pivalate | The pivalate thioester of tixocortol. | tixocortol pivalate |
| toluene 2,4-diisocyanate | A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring. | toluene 2,4-diisocyanate |
| triforine | A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust. | triforine |
| trimellitic anhydride | A 2-benzofuran compound having oxo groups at the 1- and 3-positions and a carboxy substituent at the 5-position; the cyclic anhydride formed from the carboxy groups at the 1- and 2-positions of trimellitic acid. | trimellitic anhydride |
| tylosin | A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of Streptomyces fradiae. | tylosin |
| uracil | A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. | uracil |
| veratric acid | A member of the class of benzoic acids that is benzoic acid substituted by methoxy groups at positions 2 and 3. | 3,4-dimethoxybenzoic acid |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 17.5594 | 1 | 2 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 15.8269 | 1 | 6 |
| 67.9K protein | Vaccinia virus | Potency | 17.9865 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 56.3123 | 4 | 24 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 28.2214 | 2 | 15 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 26.7732 | 1 | 15 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 1.7783 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 39.1024 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 29.2843 | 12 | 183 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 31.2476 | 3 | 52 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 22.0505 | 2 | 6 |
| Ataxin-2 | Homo sapiens (human) | Potency | 36.2154 | 1 | 23 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.1694 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 34.9298 | 2 | 32 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 54.5550 | 1 | 3 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 15.5062 | 1 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 19.9175 | 1 | 5 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 38.9337 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 19.9175 | 1 | 5 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 38.9337 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 37.8333 | 3 | 46 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 14.9763 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 15.1861 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 52.8117 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 30.1056 | 1 | 5 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 16.3132 | 1 | 4 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 8.4040 | 2 | 4 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 53.6975 | 1 | 5 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 10.9049 | 1 | 9 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 4.9171 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 24.2136 | 1 | 8 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 8.4040 | 2 | 4 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 54.5928 | 1 | 6 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 22.2003 | 1 | 7 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 10.3988 | 1 | 7 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 21.6271 | 2 | 20 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 12.1520 | 2 | 11 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 28.9230 | 1 | 30 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 30.5765 | 1 | 7 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 44.6255 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 32.6914 | 12 | 216 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 30.3462 | 3 | 25 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 33.6077 | 10 | 166 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 4.0188 | 1 | 7 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 5.0127 | 4 | 4 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 20.1748 | 1 | 2 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 33.0360 | 5 | 35 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 22.2003 | 1 | 7 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 21.6271 | 1 | 10 |
| geminin | Homo sapiens (human) | Potency | 10.4106 | 2 | 15 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 23.5285 | 3 | 63 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 18.6165 | 2 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 15.1861 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 27.4882 | 5 | 55 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 36.6362 | 1 | 22 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 37.7881 | 1 | 3 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 37.1194 | 2 | 25 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 4.5040 | 1 | 6 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 22.7312 | 1 | 6 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 36.9065 | 2 | 20 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 46.2108 | 2 | 33 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 22.2003 | 1 | 7 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 9.9399 | 3 | 4 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 34.4832 | 2 | 20 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 27.2173 | 3 | 5 |
| IDH1 | Homo sapiens (human) | Potency | 13.9250 | 1 | 4 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 22.2003 | 1 | 14 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 19.9608 | 2 | 8 |
| interleukin 8 | Homo sapiens (human) | Potency | 73.1883 | 1 | 4 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 12.9932 | 1 | 7 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 28.3708 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 28.2956 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 41.5709 | 3 | 27 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 15.5110 | 2 | 5 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 27.7073 | 4 | 82 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 24.5192 | 1 | 2 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 39.1102 | 1 | 4 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 44.2689 | 2 | 17 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 28.7428 | 1 | 16 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 19.2648 | 2 | 16 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 23.7531 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 32.3318 | 3 | 91 |
| P53 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 55.2800 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 12.4037 | 2 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 33.8240 | 5 | 32 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 33.2451 | 5 | 34 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 59.7121 | 3 | 5 |
| PINK1 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 6.4007 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 7.9960 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 4.5040 | 1 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 29.6695 | 1 | 8 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 34.4436 | 3 | 44 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 49.7617 | 1 | 8 |
| progesterone receptor | Homo sapiens (human) | Potency | 37.8061 | 2 | 23 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 51.5568 | 2 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 23.4016 | 2 | 61 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 38.1456 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 30.8186 | 3 | 94 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 24.9183 | 4 | 48 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 18.8541 | 1 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 25.1459 | 2 | 10 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 25.1459 | 2 | 10 |
| Smad3 | Homo sapiens (human) | Potency | 15.8048 | 4 | 10 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 24.5356 | 1 | 7 |
| TDP1 protein | Homo sapiens (human) | Potency | 13.2357 | 2 | 26 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 6.6879 | 1 | 3 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 29.1303 | 2 | 7 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 25.9383 | 3 | 56 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 30.6201 | 4 | 13 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 28.1172 | 7 | 49 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 16.6978 | 2 | 5 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 6.4007 | 1 | 3 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 6.4007 | 1 | 3 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 53.7621 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 36.4218 | 2 | 26 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 29.4554 | 5 | 28 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 31.2873 | 5 | 8 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 36.6362 | 1 | 22 |
| Vpr | Human immunodeficiency virus 1 | Potency | 28.1838 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 0.3790 | 1 | 1 |
| [tau protein] kinase | Oryctolagus cuniculus (rabbit) | IC50 | 100.0000 | 1 | 1 |
| 30S ribosomal protein S1 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 0.7470 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.4270 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 0.7470 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.4270 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 5.2760 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 2.4500 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | IC50 | 8.2000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | IC50 | 70.1000 | 1 | 1 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | IC50 | 0.0320 | 1 | 1 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 3,013.0100 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 0.3470 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 0.1960 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 96.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 2.5190 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | Ki | 253.0000 | 1 | 3 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 2.4985 | 1 | 2 |
| Alpha-(1,3)-fucosyltransferase 7 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3470 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1960 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3470 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1960 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 0.8990 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.3370 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 25,059,350,010.0000 | 2 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.1620 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.0740 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 25,059,350,010.0000 | 2 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 1.6580 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.2410 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 25,059,350,010.0000 | 2 | 2 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 300.0000 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 189.4835 | 1 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 350.2500 | 3 | 4 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 2.4050 | 1 | 1 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 0.9290 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | IC50 | 1.8100 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Ki | 2.0476 | 1 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Rattus norvegicus (Norway rat) | Ki | 0.5103 | 4 | 5 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Capsid protein | Hepatitis B virus | IC50 | 50.0500 | 2 | 2 |
| Carbonic anhydrase | Methanosarcina thermophila | Ki | 11,700.0000 | 2 | 2 |
| Carbonic anhydrase | Astrosclera willeyana | Ki | 320.0000 | 1 | 1 |
| Carbonic anhydrase | Pseudomonas aeruginosa PAO1 | Ki | 7,000.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 5,783.8665 | 11 | 23 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 479.3200 | 3 | 15 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 525.7929 | 2 | 14 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 447.6627 | 3 | 15 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 335.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 44,756.6962 | 20 | 32 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 479.5429 | 2 | 14 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 496.9053 | 3 | 15 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 540.7929 | 2 | 14 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 525.2214 | 2 | 14 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 450.1347 | 3 | 15 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 538.0167 | 3 | 15 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 481.9567 | 3 | 15 |
| Chain A, PROTEIN (TRYPSIN) | Bos taurus (cattle) | Ki | 1,580.0000 | 1 | 2 |
| Chain A, Uracil-DNA Glycosylase | Thermus thermophilus | Ki | 0.0880 | 1 | 1 |
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 36.2900 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 3.4443 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 1.1890 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 0.5950 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 5.8660 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 1.9550 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 0.8510 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.2890 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 9.1800 | 1 | 1 |
| fMet-Leu-Phe receptor | Homo sapiens (human) | IC50 | 66.7000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 0.3100 | 1 | 1 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | IC50 | 36.2900 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 63.0250 | 3 | 4 |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | IC50 | 900.0000 | 1 | 1 |
| glutathione-S-transferase | Schistosoma japonicum | IC50 | 58.0400 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| High affinity choline transporter 1 | Mus musculus (house mouse) | IC50 | 1.6000 | 1 | 1 |
| Histone acetyltransferase KAT2B | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Histone acetyltransferase KAT8 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 450.0000 | 2 | 2 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 1.2430 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 0.4970 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 9.0100 | 1 | 1 |
| Lecithin retinol acyltransferase | Homo sapiens (human) | IC50 | 14.9000 | 1 | 1 |
| Lethal factor | Bacillus anthracis | Ki | 0.2535 | 2 | 2 |
| Lysine--tRNA ligase | Homo sapiens (human) | IC50 | 0.0277 | 1 | 1 |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | IC50 | 64.7000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Matrilysin | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | IC50 | 3.9000 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | Ki | 3.7000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 3.1130 | 1 | 1 |
| Mu-type opioid receptor | Mus musculus (house mouse) | IC50 | 500.0000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 1.2640 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 89,000.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 34.0000 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 42.2500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 38.7500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | IC50 | 36.2900 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 35.2000 | 4 | 5 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 41.5000 | 3 | 4 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 32.2655 | 1 | 2 |
| P2X purinoceptor 4 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 1,874,470,116.3333 | 3 | 3 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 135.6333 | 5 | 6 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 1.3700 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 4.8920 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 20,000.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 1.0190 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 18.9200 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 2.8130 | 2 | 2 |
| Protein cereblon | Homo sapiens (human) | IC50 | 415.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | Ki | 212.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 0.1600 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 1.6960 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.7130 | 1 | 1 |
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 0.2450 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.1940 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 2.5190 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 2.4985 | 1 | 2 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | Ki | 30,000.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 19,000.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 55.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 925.0000 | 2 | 2 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 217.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 804.5000 | 2 | 2 |
| Succinate-semialdehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Thiopurine S-methyltransferase | Homo sapiens (human) | IC50 | 1,492.0150 | 1 | 2 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 8 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Trypsin-1 | Homo sapiens (human) | Ki | 299,916.0000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Tyrosyl-DNA phosphodiesterase 1 | Homo sapiens (human) | IC50 | 8,000.0000 | 1 | 1 |
| Vif | Human immunodeficiency virus 1 | IC50 | 9.1800 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 54.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 54.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 54.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 54.2000 | 1 | 1 |