Albinism, Oculocutaneous

Heterogeneous group of autosomal recessive disorders comprising at least four recognized types, all having in common varying degrees of hypopigmentation of the skin, hair, and eyes. The two most common are the tyrosinase-positive and tyrosinase-negative types.

Synonym
Albinism, Oculocutaneous

Excerpt	Reference
"Oculocutaneous albinism is a group of autosomal recessive disorders that directly affect the hypopigmentation of the skin, hair, and eyes."	( Sobolev, NP; Sudakova, EP; Teplovodskaya, VV, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	7 (5.34)	23.3326
1990's	43 (32.82)	12.5806
2000's	32 (24.43)	18.1394
2010's	39 (29.77)	28.8240
2020's	10 (7.63)	9.53

Drug	Relationship Strength	Studies	Trials
lactic acid	low	1	0
hydroquinone	low	1	0
dihydroxyphenylalanine	low	8	0
naphthalene	low	1	0
baclofen	low	1	0
busulfan	low	1	0
flumazenil	low	1	0
2-propanol	low	15	0
khellin	medium	1	1
mechlorethamine	low	1	0
methylphenidate	low	1	0
pyrimethamine	low	1	0
sulfasalazine	low	1	0
penicillamine	low	1	0
pilocarpine	low	1	0
glutamine	low	1	0
sucrose	low	1	0
adenosine diphosphate	low	2	0
bromodeoxyuridine	low	2	0
tyrosine	low	19	0
phenylalanine	low	3	0
histidine	low	1	0
arginine	low	2	0
ethylene	low	1	0
quinoxalines	low	2	0
cyclopentane	low	1	0
thiazoles	low	1	0
pyrimidine	low	1	0
d-alpha tocopherol	low	1	0
amiloride	low	1	0
mannose	low	1	0
platinum	low	1	0
argon	medium	1	1
magnesium sulfate	low	1	0
zinc sulfate	low	1	0
tiletamine hydrochloride	low	3	0
nsc-172755	low	1	0
nitisinone	low	3	0
5-s-cysteinyldopamine	low	1	0
5-hydroxy-6-methoxy-2-indolylcarboxylic acid	low	2	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
inositol 3-phosphate	low	1	0
arbutin	low	1	0
aurovertin b	low	1	0
clindamycin	low	1	0
propylthiouracil	low	1	0
unithiol	low	1	0
jasmonic acid	low	1	0
deamino arginine vasopressin	low	1	0
latanoprost	low	2	0
iridal	low	2	0
cysteine	low	1	0
carbocyanines	low	1	0
dolichols	low	1	0
thiazole orange	low	1	0
brimonidine tartrate	low	1	0
deoxyarbutin	low	1	0
cysteinyldopa	low	1	0
oligonucleotides	low	1	0
tetracycline	low	1	0
oligomycins	low	1	0
guanosine triphosphate	low	1	0
sapropterin	low	2	0
pheophytin a	low	1	0
eye	low	12	0

Protein Targets (615)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
RAR-related orphan receptor gamma	8	0	0	8
GLI family zinc finger 3	7	0	0	7
AR protein	15	0	0	15
aldehyde dehydrogenase 1 family, member A1	13	0	0	13
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
retinoid X nuclear receptor alpha	8	0	0	8
estrogen nuclear receptor alpha	19	0	0	19
peroxisome proliferator-activated receptor delta	5	0	0	5
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	4	0	0	4
activating transcription factor 6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
Histone H2A.x	5	0	0	5
thyroid hormone receptor beta isoform a	3	0	0	3
heat shock protein beta-1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
lamin isoform A-delta10	10	0	0	10
Voltage-dependent calcium channel gamma-2 subunit	5	0	0	5
Glutamate receptor 2	6	0	0	6
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	7	0	0	7
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	2	3
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	0	1	1
Delta-type opioid receptor	0	0	1	1
Kappa-type opioid receptor	0	0	1	1
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	1	0	0	1
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
acid sphingomyelinase	1	0	0	1
acetylcholinesterase	3	0	0	3
thioredoxin reductase	12	0	0	12
TDP1 protein	13	0	0	13
thyroid stimulating hormone receptor	6	0	0	6
glucocorticoid receptor [Homo sapiens]	11	0	0	11
glucocerebrosidase	1	0	0	1
arylsulfatase A	7	0	0	7
alpha-galactosidase	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	13	0	0	13
Bloom syndrome protein isoform 1	7	0	0	7
cytochrome P450 2D6 isoform 1	4	0	0	4
lysosomal alpha-glucosidase preproprotein	1	0	0	1
cytochrome P450 2C19 precursor	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
thyroid hormone receptor beta isoform 2	5	0	0	5
huntingtin isoform 2	1	0	0	1
geminin	11	0	0	11
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Bile salt export pump	0	13	0	13
Prothrombin	0	1	0	1
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	1	0	1
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	5
Vitamin K-dependent protein C	0	1	0	1
Cellular tumor antigen p53	5	0	0	5
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Trypsin-3	0	1	0	1
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
Smad3	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
IDH1	3	0	0	3
Polyphenol oxidase 2	0	3	0	8
Tyrosinase	0	2	0	2
Tyrosinase	0	3	0	3
Polyphenol oxidase 1	0	1	0	1
Taste receptor type 2 member 16	0	0	1	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
phosphopantetheinyl transferase	9	0	0	9
NFKB1 protein, partial	3	0	0	3
GLS protein	6	0	0	6
chromobox protein homolog 1	8	0	0	8
flap endonuclease 1	7	0	0	7
DNA polymerase iota isoform a (long)	2	0	0	2
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	4	0	0	4
Cytochrome P450 3A4	0	1	0	2
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	1	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	6	0	0	6
ATAD5 protein, partial	5	0	0	5
67.9K protein	4	0	0	4
D(1A) dopamine receptor	1	0	0	1
cytochrome P450 3A4 isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	7	2	0	9
ATP-binding cassette sub-family C member 3	0	8	0	8
Multidrug resistance-associated protein 4	0	8	0	8
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	7	2	0	9
Gamma-aminobutyric acid receptor subunit delta	7	2	0	9
Gamma-aminobutyric acid receptor subunit gamma-2	7	2	1	10
Gamma-aminobutyric acid receptor subunit alpha-5	7	2	0	9
Gamma-aminobutyric acid receptor subunit alpha-3	7	2	0	9
Gamma-aminobutyric acid receptor subunit gamma-1	7	2	0	9
Gamma-aminobutyric acid receptor subunit alpha-2	7	2	0	9
Gamma-aminobutyric acid receptor subunit alpha-4	7	2	0	9
Gamma-aminobutyric acid receptor subunit gamma-3	7	2	0	9
Gamma-aminobutyric acid receptor subunit alpha-6	7	2	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	7	2	1	10
Gamma-aminobutyric acid receptor subunit beta-3	7	2	0	9
Gamma-aminobutyric acid receptor subunit beta-2	7	2	1	10
GABA theta subunit	7	2	0	9
Canalicular multispecific organic anion transporter 1	0	7	0	7
Gamma-aminobutyric acid receptor subunit epsilon	7	2	0	9
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
interleukin 8	3	0	0	3
pregnane X receptor	3	0	0	3
Microtubule-associated protein tau	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
progesterone receptor	5	0	0	5
estrogen-related nuclear receptor alpha	8	0	0	8
pregnane X nuclear receptor	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
Nuclear hormone receptor family member daf-12	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
peripheral myelin protein 22	8	0	0	8
survival motor neuron protein isoform d	6	0	0	6
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Nuclear receptor ROR-gamma	3	0	0	3
Spike glycoprotein	6	0	0	6
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
ATPase family AAA domain-containing protein 5	3	0	0	3
Ataxin-2	3	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
15-lipoxygenase, partial	5	0	0	5
apical membrane antigen 1, AMA1	2	0	0	2
EWS/FLI fusion protein	8	0	0	8
aryl hydrocarbon receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Matrix metalloproteinase-9	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Protein-arginine deiminase type-4	0	2	0	2
endonuclease IV	4	0	0	4
dopamine D1 receptor	2	0	0	2
peroxisome proliferator activated receptor gamma	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
peripheral myelin protein 22 isoform 1	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
M-phase phosphoprotein 8	3	0	0	3
Glucocorticoid receptor	0	2	0	2
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	2	0	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
USP1 protein, partial	3	0	0	3
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
mitogen-activated protein kinase 1	3	0	0	3
DNA polymerase kappa isoform 1	3	0	0	3
Epidermal growth factor receptor	0	2	0	2
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Caspase-7	1	0	0	1
G	3	0	0	3
nuclear receptor ROR-gamma isoform 1	3	0	0	3
muscleblind-like protein 1 isoform 1	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Bile salt export pump	0	3	0	3
Interferon beta	5	0	0	5
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Inositol hexakisphosphate kinase 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
cytochrome P450 2C9, partial	3	0	0	3
Chain A, Glutamine Binding Protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Carbonic anhydrase 1	0	5	0	11
Carbonic anhydrase 2	0	6	1	13
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	5
Amino acid transporter	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Carbonic anhydrase 12	0	2	0	6
Carbonic anhydrase 3	0	2	0	6
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 4	0	2	0	6
Carbonic anhydrase 6	0	2	0	6
Adenosine receptor A1	0	0	0	4
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	0	0	4
Carbonic anhydrase 5A, mitochondrial	0	2	0	6
Glutamate receptor ionotropic, NMDA 1	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase 7	0	2	0	6
Carbonic anhydrase	0	0	0	4
Glutamate receptor ionotropic, NMDA 2A	0	0	0	4
Glutamate receptor ionotropic, NMDA 2B	0	0	0	4
Glutamate receptor ionotropic, NMDA 2C	0	0	0	4
Large neutral amino acids transporter small subunit 1	0	4	0	5
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	3	1	8
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase 13	0	0	0	2
Glutamate receptor ionotropic, NMDA 3B	0	0	0	4
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 15	0	2	0	6
Carbonic anhydrase 13	0	2	0	5
Glutamate receptor ionotropic, NMDA 3A	0	0	0	4
Carbonic anhydrase 14	0	2	0	6
Carbonic anhydrase 5B, mitochondrial	0	2	0	6
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Nrf2	1	0	0	1
Thrombopoietin	1	0	0	1
DNA polymerase III, partial	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
estrogen receptor 2 (ER beta)	3	0	0	3
farnesoid X nuclear receptor	3	0	0	3
cytochrome P450 2D6	4	0	0	4
Parkin	1	0	0	1
thyroid stimulating hormone receptor	4	0	0	4
Caspase-7	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
hemoglobin subunit beta	1	0	0	1
caspase-3	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
Acetylcholinesterase	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Carbonic anhydrase	0	2	0	2
large T antigen	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
glp-1 receptor, partial	2	0	0	2
GALC protein	2	0	0	2
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1A2	0	3	0	3
Cytochrome P450 2D6	0	1	0	1
Cytochrome P450 2C9	0	3	0	3
Cytochrome P450 2C19	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
Chain A, Beta-lactamase	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Luciferase	3	0	0	3
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
phosphoglycerate kinase	1	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
Fumarate hydratase	2	0	0	2
PPM1D protein	1	0	0	1
polyprotein	2	0	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Cytochrome P450 2A6	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
cytochrome P450 2C9 precursor	2	0	0	2
Muscarinic acetylcholine receptor M2	0	2	1	3
Muscarinic acetylcholine receptor M1	0	2	0	3
Muscarinic acetylcholine receptor M3	0	2	0	3
Muscarinic acetylcholine receptor M4	0	2	0	3
Muscarinic acetylcholine receptor M5	0	2	0	3
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	2	0	3
Muscarinic acetylcholine receptor M1	0	1	2	3
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Histamine H2 receptor	2	0	0	2
Cytochrome P450 2A13	0	1	1	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Myeloperoxidase	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
streptokinase A precursor	0	0	1	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Dihydrofolate reductase	0	2	1	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Chain A, Glutathione S-transferase	0	1	0	1
Replicase polyprotein 1ab	0	0	1	1
histone deacetylase 9 isoform 3	1	0	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
ATP-dependent translocase ABCB1	0	0	1	1
Androgen receptor	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Mitogen-activated protein kinase 1	0	1	0	1
Caspase-1	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	2
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Alpha-synuclein	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (131)

Protein Targets (615)

Albinism, Oculocutaneous

Synonyms(1)

Research Excerpts

Overview

Research

Studies (131)

Drugs Studied (90)

Protein Targets (615)