A proteinogenic amino acid derivative resulting from reaction of L-serine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-serine by a heteroatom.
ChEBI ID: 84135
| Member | Definition | Role |
|---|---|---|
| 2,3-dihydroxybenzoylserine | N-(2,3-dihydroxybenzoyl)-L-serine | |
| azaserine | A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species. | azaserine |
| cefoxitin | A non-proteinogenic L-amino acid that is N-acetyl-alpha-D-galactosamine linked via an alpha glycosidic bond to the O at position 3 of L-serine. | O-(N-acetyl-alpha-D-galactosaminyl)-L-serine |
| glycerophosphoserine | A L-serine derivative consisting of L-serine having a 1-glycerophospho group attached to the side-chain hydroxy function. | glycerol 1-phosphoserine |
| i-677 | An L-alpha-amino acid that is L-serine in which the hydroxy group at position 3 is converted to the corresponding 2-aminoethyl ether. An antimetabolic antibiotic obtained from Streptomyces reseoviridofuscus. | O-(2-aminoethyl)-L-serine |
| o-methylserine | A serine derivative that is L-serine with a methyl group replacing the hydrogen on the hydroxy side chain. | O-methylserine |
| serine o-sulfate | A non-proteinogenic L-alpha-amino acid that is the O-sulfo derivative of L-serine. | L-serine O-sulfate |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 467 (42.65) | 18.7374 |
| 1990's | 239 (21.83) | 18.2507 |
| 2000's | 167 (15.25) | 29.6817 |
| 2010's | 174 (15.89) | 24.3611 |
| 2020's | 48 (4.38) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 7 (0.62%) | 5.53% |
| Reviews | 58 (5.10%) | 6.00% |
| Case Studies | 10 (0.88%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,062 (93.40%) | 84.16% |