Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Reference |
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| "Sepsis is a major catabolic insult resulting in modifications in carbohydrate and fat energy metabolism, and leading to increased muscle breakdown and nitrogen loss." | ( Fischer, JE; Freund, HR; Ryan, JA, 1978) |
| "Sepsis is a major catabolic insult resulting in a peripheral energy deficit which is made up in part by increased breakdown of lean body mass and oxidation of amino acids, principally the branched chain amino acids." | ( Atamian, S; Fischer, JE; Freund, H; Holroyde, J, 1979) |
| "Sepsis is lessened by the use of prophylactic antibiotics." | ( Hill, D; Jamieson, CW, 1976) |
| "Sepsis is frequently characterized by a number of metabolic abnormalities: increased plasma lactate concentration, metabolic acidosis, increased glycolysis, and an abnormal "delivery-dependent" oxygen consumption." | ( Hotchkiss, RS; Karl, IE, 1992) |
| "Sepsis is characterized by Adult Respiratory Distress Syndrome (ARDS)-like pulmonary dysfunction largely attributed to alveolar capillary endothelial cell injury which causes increased microvascular permeability and interstitial edema formation." | ( Guice, KS; Oldham, KT; Stetson, PS; Wolfe, RR, 1989) |
| "Hyperdynamic sepsis is associated with a redistribution of organ blood flow." | ( Martin, CM; Sibbald, WJ, 1994) |
| "Sepsis is a common cause of morbidity and mortality." | ( Millard, FE; Samuelson, D; Sharpe, RW; Smith, WS; Sumnicht, GE, 1995) |
| "Sepsis is an intriguing pathological condition associated with many complex metabolic and physiological alterations." | ( Goldman, RK; Trunkey, DD; Vlessis, AA, 1995) |
| "Because sepsis is currently the major factor in 75% of burn deaths, donor-specific tolerance for skins grafts appears to be eminently reasonable for future consideration." | ( Cunningham, P; Garrison, JL; Thomas, F, 1995) |
| "Normotensive sepsis is accompanied by increased vascular permeability in the diaphragm and intra-abdominal organs." | ( Flammand, FJ; Girotti, MJ; Martin, CM; Sibbald, WJ, 1995) |
| "Sepsis is the systemic inflammatory response resulting from serious infection and is the most common cause of death in intensive care units." | ( Hotchkiss, RS; Karl, IE, 1994) |
| "Sepsis is associated with a decrease in the intrinsic gluconeogenic capacity of hepatocytes." | ( Buchman, TG; Clemens, MG; De Maio, A; Deutschman, CS, 1993) |
| "Sepsis is characterized by myocardial depression and systemic vasodilation, both of which are most likely mediated by nitric oxide." | ( Armstrong, C; Booke, M; Conroy, B; Hinder, F; Traber, DL; Traber, LD, 1996) |
| "Sepsis is associated with markedly increased plasma concentrations of adhesion molecules, indicating endothelial activation or damage." | ( Boldt, J; Heesen, M; Hempelmann, GG; Muller, M; Neumann, K, 1996) |
| "Traditionally, sepsis is defined as a systemic inflammatory reaction of the organism to Gram-negative bacterial leading to septic shock--characterized by hemodynamic derangements--and eventually to septic multi-organ malfunction." | ( Ahmad, S, 1995) |
| "Sepsis is associated with disruption of virtually all these provisional sources of energy substrate (see Fig." | ( Crouser, ED; Dorinsky, PM, 1996) |
| "In conclusion, sepsis is characterized by high basal cortisol level which may show a poor prognosis and a blunted cortisol response to ACTH stimulation." | ( Aygen, B; Doğanay, M; Inan, M; Keleştimur, F, 1997) |
| "Sepsis is associated with alterations in glucose metabolism and the effect of intravenous feeding on energy expenditure is unclear." | ( Arnold, J; Carlson, GL; Gray, P; Irving, MH; Little, RA, 1997) |
| "Although sepsis is known to affect vascular function, little is known about changes at the capillary level." | ( McCormack, DG; Tyml, K; Yu, J, 1998) |
| "Sepsis is associated with reduced protein synthesis and increased protein degradation in skeletal muscle." | ( Fischer, JE; Hasselgren, PO; Hobler, SC; Williams, AB, 1998) |
| "Sepsis is believed to increase the risk of bilirubin brain toxicity, but the mechanism is not known." | ( Allen, JW; Carcillo, J; Hansen, TW; Tommarello, S, 1998) |
| "Sepsis is associated with hemodynamic and metabolic alterations which may affect the pharmacokinetics of crosslinked hemoglobin." | ( Chin-Yee, IH; d'Almeida, MS; Sibbald, WJ; White, M, 1998) |
| "Sepsis is associated with enhanced cytokine production." | ( Camussi, G; Cavaillon, JM; Curti, F; Ghezzi, PM; Lonnemann, G; Ronco, C; Schulze, M; Serra, AM; Tetta, C, 1998) |
| "Meningococcal sepsis is associated with a high mortality rate." | ( Arévalo, JM; Fonseca, R; Lorente, JA, 1998) |
| "Sepsis is associated with poor wound healing; however, the exact role of tumor necrosis factor (TNF) as a mediator of sepsis-induced alterations in different types of tissue repair is unknown." | ( Cooney, RN; Ehrlich, HP; Maish, GO; Shumate, ML, 1998) |
| "Sepsis is an increasingly common and lethal diagnosis in hospitalized patients." | ( Chen, HW; Chou, FP; Hwang, KP; Lue, SI; Wang, CI; Yang, RC, 1998) |
| "Sepsis is a major cause of death in intensive care units." | ( Barzilai, B; Courtois, MR; Hotchkiss, RS; Karl, IE; Kovacs, A; Ludbrook, PA, 1998) |
| "Polymicrobial sepsis is characterized by an early, hyperdynamic phase followed by a late, hypodynamic phase." | ( Chaudry, IH; Ornan, DA; Wang, P, 1999) |
| "Sepsis is associated with a pronounced catabolic response in skeletal muscle, mainly reflecting degradation of the myofibrillar proteins actin and myosin." | ( Decourten-Myers, GM; Fischer, JE; Hasselgren, PO; Luo, G; Sun, X; Williams, AB, 1999) |
| "Sepsis is defined as the systemic inflammatory response to infection." | ( Dana, R; Hazan, I; Levy, I; Levy, R; Pesach, I; Riesenberg, K; Schlaeffer, F; Smoliakov, R; Weber, G, 2000) |
| "Polymicrobial sepsis is characterized by an early, hyperdynamic phase (i." | ( Chaudry, IH; Ornan, DA; Shieh, P; Wang, P; Zhou, M, 2000) |
| "Sepsis is a global problem which is exacerbated by increasing bacterial resistance to antibiotics." | ( Bullen, J; Griffiths, E; Rogers, H; Ward, G, 2000) |
| "Polymicrobial sepsis is characterized by an early, hyperdynamic phase followed by a late, hypodynamic phase." | ( Chaudry, IH; Ornan, DA; Wang, P, 2000) |
| "Cerebral oedema and sepsis are the major fatal complications." | ( Acharya, SK; Gupta, SD; Panda, SK; Saxena, A, 2000) |
| "Sepsis is a state of high turnover of bone-marrow cells." | ( Barthlen, W; Holzmann, B; Klemens, C; Rogenhofer, S; Stadler, J; Unbehaun, N, 2000) |
| "Neonatal sepsis is a major problem in newborn nurseries because of the difficulty in early diagnosis and because of the high morbidity and mortality." | ( Atalay, Y; Erbaş, D; Ergenekon, E; Gücüyener, K; Koç, E; Ozturk, G, 2000) |
| "Sepsis is associated with increased muscle proteolysis and upregulated transcription of several genes in the ubiquitin-proteasome proteolytic pathway." | ( Fischer, JE; Gang, G; Hasselgren, PO; Penner, CG; Wray, C, 2001) |
| "Sepsis is associated with a marked depression of cellular immune function." | ( Dahlweid, M; Emmendörfer, A; Koch, R; Oberbeck, R; Pape, HC; Tscherne, H; van Griensven, M, 2001) |
| "Sepsis is the leading cause of death in surgical intensive care units." | ( Andrejko, KM; Bellin, L; Deutschman, CS; Furth, EE; Haaxma, CA; Kim, PK; Raj, N; Weiss, YG, 2001) |
| "Sepsis is associated with increased intestinal permeability, but mediators and mechanisms are not fully understood." | ( Fang, CH; Hasselgren, PO; Wang, Q, 2001) |
| "Neonatal bacterial sepsis is often characterized by a fulminant clinical course and highly elevated plasma levels of proinflammatory cytokines." | ( Berner, R; Brandis, M; Welter, P, 2002) |
| "Sepsis is associated with a widespread production of proinflammatory cytokines and various oxidant species." | ( Liaudet, L; Mabley, JG; Pacher, P; Soriano, FG; Szabó, C; Szabó, E; Virág, L, 2002) |
| "Bacterial sepsis is frequently accompanied by increased blood concentration of lactic acid, which traditionally is attributed to poor tissue perfusion, hypoxia and anaerobic glycolysis." | ( Fischer, JE; Friend, LA; James, JH; King, JK; McCarter, FD; Nierman, SR; Wang, L, 2002) |
| "Sepsis is known to be associated with oxidative stress." | ( Ekmekcioglu, C; Marktl, W; Mundigler, G; Schweiger, B; Siostrzonek, P; Strauss-Blasche, G, 2002) |
| "Sepsis is associated with oxidative stress and impaired glutamatergic transmission in brain." | ( Hammond, RR; Korcok, J; Tyml, K; Wilson, JX; Wu, F, 2002) |
| "Polymicrobial sepsis is characterized by an early, hyperdynamic phase followed by a late, hypodynamic phase." | ( Chaudry, IH; Wang, P; Yang, S; Zhou, M, 2002) |
| "Sepsis is a pathophysiologic state characterized by vasodilation mediated, at least in part, by an excessive release of nitric oxide." | ( Alonso, M; Blázquez, J; De Paula, M; Delgado, MA; Esteban, A; Fernández-Segoviano, P; Lorente, JA; Moscoso, A; Soto, F; Tejedor, C; Tobalina, R, 2002) |
| "Neonatal sepsis is frequently associated with pathological activation of the coagulation system, leading to multiple organ dysfunction." | ( Bocheński, P; Kornacka, MK; Rawicz, M; Rudzińska, I; Sitkowska, B, 2002) |
| "Severe sepsis is accompanied by a profound depression of myocardial contractility." | ( Braun-Dullaeus, RC; Dietrich, S; Haberbosch, W; Kummer, W; Leithaeuser, B; Matthias, RF; Schoaff, MJ; Seay, U; Sedding, DG; Tillmanns, H; Walker, G, 2003) |
| "Late stages of sepsis are associated with impairments of T lymphocyte function, a condition associated with nosocomial infection and poor outcome." | ( Aasen, A; Solberg, R; Solhaug, V; Taskén, K; Vang, T; Wang, JE; Yaqub, S, 2003) |
| "Sepsis is associated with secretory pancreatic dysfunction that is worse in septic shock than in sepsis without shock." | ( Gangl, A; Madl, C; Sibbald, WJ; Spitzauer, S; Tribl, B; Vogelsang, H, 2003) |
| "In contrast, sepsis is an inflammatory state mainly mediated by bacterial products." | ( Bland, KI; Chaudry, IH; Schwacha, MG; Yokoyama, Y, 2003) |
| "Neonatal sepsis is very common in preterm infants, and severe morbidity during the neonatal period is a major cause of osteopenia of prematurity." | ( Dolfin, T; Eliakim, A; Nemet, D; Shiff, Y, 2003) |
| "Sepsis is a life-threatening event when it occurs in patients suffering from smoke inhalation injury." | ( Cox, RA; Hawkins, HK; Jodoin, JM; McGuire, RW; Murakami, K; Schmalstieg, FC; Traber, DL; Traber, LD, 2003) |
| "Surgical sepsis is still too frequent (the thirteenth cause of death in the U." | ( Carnuccio, P; Colizza, S; Cucchiara, G; Rodio, F; Rossi, S, 2003) |
| "The fact that wound sepsis is still prevalent is emphasized, and recent researches on bacterial inhibition under hyperbaric oxygen are described." | ( ILLINGWORTH, C, 1964) |
| "The pathogenesis of sepsis is still undetermined to a large extent." | ( Hildebrand, F; Hoevel, P; Krettek, C; Pape, HC; van Griensven, M, 2003) |
| "Sepsis is one of the major causes of mortality in critically ill patients and develops as a result of the host response to infection." | ( Brunner, J; Kirkpatrick, CJ; Peters, K; Unger, RE, 2003) |
| "Sepsis is a common cause of acute renal failure (ARF)." | ( Hewitt, SM; Hu, X; Iyer, S; Miyaji, T; Muramatsu, Y; Star, RA; Yuen, PS, 2003) |
| "Although sepsis is the major cause of mortality and morbidity in the critically ill, precise mechanism(s) causing multiorgan dysfunction remain unclear." | ( Brealey, D; Jacques, TS; Karyampudi, S; Novelli, M; Singer, M; Smolenski, RT; Stidwill, R; Taylor, V, 2004) |
| "Gram-negative sepsis is a potentially fatal clinical syndrome characterized by a proinflammatory response (tumor necrosis factor-alpha) to bacterial (endo)toxins and gut barrier function loss." | ( Buurman, WA; Dejong, CH; Greve, JW; Hadfoune, M; Jacobs, JA; Konstantinov, SR; Luyer, MD, 2004) |
| "Sepsis is commonly associated with enhanced generation of reactive oxygen metabolites, which lead to multiple organ dysfunction." | ( Ayanoğlu-Dülger, G; Kapucu, C; Paskaloğlu, K; Sener, G, 2004) |
| "Neonatal sepsis is an important cause of morbidity and mortality as a result of multiple organ system failure, particularly in neonates requiring total parenteral nutrition." | ( Eaton, S, 2003) |
| "Sepsis is the most common cause of death in intensive care units worldwide." | ( Avadhani, NG; Deutschman, CS; Levy, RJ; Raj, NR; Vijayasarathy, C, 2004) |
| "Infections and sepsis are among the most devastating complications in abdominal surgery and significantly contribute to morbidity and mortality." | ( Krüger, CM; Rau, B; Schilling, MK, 2004) |
| "Lung edema during sepsis is triggered by formation of gaps between endothelial cells followed by macrophage infiltration." | ( Gilmont, RR; Hata, J; Hirano, S; Rees, RS; Remick, DG; Welsh, MJ; Yamada, T; Yancy, SL, 2004) |
| "Sepsis is currently treated with antibiotics and various adjunctive therapies that are not very effective." | ( Fang, G; Linden, J; Scheld, WM; Sullivan, GW, 2004) |
| "Nosocomial sepsis is a serious problem for neonates who are admitted for intensive care." | ( Benjamin, DK; Bloom, B; Clark, R; Powers, R; Sanchez, P; White, R, 2004) |
| "Sepsis is an acute inflammatory disease characterized by dysfunctional blood flow and hypotension." | ( Chacko, BK; Crawford, JH; Hogg, N; Patel, RP; Piknova, B; Pruitt, HM, 2004) |
| "Sepsis is caused by a dysregulated immune response to infection and, without intervention, can lead to septic shock and multiple organ failure." | ( Smithies, MN; Weaver, CB, 2004) |
| "Sepsis is characterized by an early, hyperdynamic phase and a late, hypodynamic phase." | ( Cui, X; Simms, HH; Wang, P; Wu, R; Zhou, M, 2004) |
| "We conclude that sepsis is associated with a significant decrease in vitamin E and an overproduction of O2- degree." | ( Amigues, L; Beraud, JJ; Canaud, B; Cristol, JP; Delbosc, S; Durant, R; Klouche, K; Morena, M, 2004) |
| "Polymicrobial sepsis is characterized by an early, hyperdynamic phase followed by a late, hypodynamic phase." | ( Simms, HH; Wang, P; Zhou, M, 2004) |
| "Sepsis is a major health problem considering its significant morbidity and mortality rate." | ( Dejong, CH; Deutz, NE; Luiking, YC; Poeze, M; Ramsay, G, 2004) |
| "Sepsis is associated with depression of T cell-dependent immune reactivity with proinflammatory cytokines, such as tumour necrosis factor (TNF)-alpha, playing an important role." | ( Harwood, P; Hildebrand, F; Krettek, C; Pape, HC; van Griensven, M; Wittwer, T, 2004) |
| "Sepsis is a generalized inflammatory response, which involves organ systems remote from the locus of the initial infectious insult, accompanied by the release of cytokines and the subsequent formation of reactive oxygen and nitrogen species." | ( Cetinel, S; Erkanli, G; Gedik, N; Sener, G; Yeğen, BC, 2005) |
| "Sepsis is initiated by interactions between microbial products and host inflammatory cells." | ( Bagchi, A; Beasley-Topliffe, LK; Fenton, MJ; Hellman, J; Lazzaroni, JC; Liang, MD; Tehan, MM; Tesini, BL; Trigilio, JA; Warren, HS, 2005) |
| "Sepsis is the most significant factor contributing to ROP." | ( Chung, CH; Chung, MY; Fang, PC; Huang, CB; Kou, HK; Liu, PM; Yang, YH, 2005) |
| "Sepsis is a leading cause of multiorgan dysfunction and death in hospitalized patients." | ( Emala, CW; Gallos, G; Lee, HT; Ruyle, TD, 2005) |
| "Sepsis is associated with the highest risk of progression to acute lung injury or the acute respiratory distress syndrome." | ( Duan, M; Li, W; Lin, N; Sun, J; Wang, Z; Xu, J; Yang, J; Zhou, Z, 2005) |
| "Sepsis is a complex clinical syndrome that results from a harmful host response to infection, in which foreign bacteria and lipopolysaccharide (LPS) are potent activators of different immune cells, including monocytes and macrophages." | ( Gengfa, L; Guo, W; Hong, Z; Jiang, Z; Liangxi, W; Yibin, G; Yongling, L, 2005) |
| "Sepsis is associated with decreased SA content on circulating transferrin and with an increase in blood free SA concentrations." | ( Boudjeltia, KZ; De Backer, D; Nuyens, V; Piagnerelli, M; Su, F; Vanhaeverbeek, M; Vincent, JL; Wang, Z, 2005) |
| "Severe sepsis is associated with increased total peripheral resistance (TPR) and decreased organ blood flow, in which endothelin-1 (ET-1) plays an important role." | ( Cui, X; Dong, W; Hank Simms, H; Wang, P; Wu, R; Zhou, M, 2005) |
| "Sepsis is associated with muscle wasting, mainly reflecting increased muscle proteolysis." | ( Evenson, AR; Fareed, MU; Hasselgren, PO; Menconi, MJ; Mitchell, JC, 2005) |
| "Sepsis is a potentially life-threatening medical condition induced by viral, bacterial or fungal infection, which is characterized by systemic inflammation, hypotension and vasodilation that can lead to cardiovascular collapse." | ( Boyle, WA; Cand, F; Faury, G; Jacob, MP; Leone, M; Verdetti, J; Wynnychenko, TM, 2005) |
| "Sepsis is commonly associated with enhanced generation of reactive oxygen metabolites, leading to multiple organ dysfunctions." | ( Arbak, S; Gedik, N; Kurtaran, P; Sener, G; Yeğen, BC, 2005) |
| "Muscle wasting in sepsis is associated with increased expression of messenger RNA for several genes in the ubiquitin-proteasome proteolytic pathway, indicating that increased gene transcription is involved in the development of muscle atrophy." | ( Evenson, A; Fareed, MU; Hasselgren, PO; Menconi, MJ; Wei, W; Yang, H, 2005) |
| "Sepsis is the leading cause of death in critically ill patients in the United States." | ( Ayala, A; Chung, CS; Garber, M; Huang, X; Perl, M, 2006) |
| "Sepsis is a generalized inflammatory response, which involves organ systems remote from the locus of the initial infectious insult, involves the release of cytokines and the subsequent formation of reactive oxygen and nitrogen species." | ( Cetinel, S; Ercan, F; Gedik, N; Sehirli, O; Sener, G; Yeğen, BC; Yüksel, M, 2005) |
| "Mortality in sepsis is believed to be associated with exaggerated inflammatory responses, but recent evidence suggests that poor outcome is associated with reduced inflammation." | ( Ahn, YS; Chirinos, JA; Horstman, LL; Jimenez, JJ; Jy, W; Kett, DH; Schein, RM; Soriano, AO; Valdivia, MA; Velasquez, HS, 2005) |
| "Sepsis is the leading cause of death in critically ill surgical patients." | ( Kim, JY; Lee, SM, 2005) |
| "Sepsis is a systemic inflammatory response to a bacterial infection." | ( Martin, C; Rose, J, 2006) |
| "Sepsis is associated with bioenergetic impairment and capillary hypoperfusion at the villus tip and a decrease in red cell flux in the central arteriole." | ( Martin, C; Rose, J, 2006) |
| "Muscle wasting in sepsis is a significant clinical problem because it results in muscle weakness and fatigue that may delay ambulation and increase the risk for thromboembolic and pulmonary complications." | ( Evenson, AR; Fareed, MU; Hasselgren, PO; Menconi, M; Petkova, V; Pignol, B; Poylin, V; Wei, W, 2006) |
| "The diagnosis of sepsis is complicated for clinical signs and symptoms are not specific and manifest in the patients who have non-infective diseases, when systemic inflammatory response is involved." | ( Andrejaitiene, J, 2006) |
| "Neonatal sepsis is one of the major health problems throughout the world." | ( Afroza, S, 2006) |
| "As sepsis is often associated with burn injury, and burn superimposed by sepsis has been shown to result in significant loss of lean tissues, we characterized changes in the skeletal-muscle proteome of rats subjected to a cutaneous burn covering 20% of the total body surface area, followed 2 days later by sepsis induced by CLP (caecal ligation and puncture)." | ( Berthiaume, F; Duan, X; Yarmush, D; Yarmush, ML, 2006) |
| "Neonates with sepsis are handicapped in terms of their defense mechanism against free radicals." | ( Basu, S; Bhatia, BD; Das, BK; Kapoor, K, 2006) |
| "Severe sepsis is frequently associated with adrenal insufficiency, which may lead to hemodynamic instability and a poor prognosis." | ( Chen, PC; Chen, YC; Fang, JT; Ho, YP; Lien, JM; Liu, NJ; Peng, YS; Tsai, MH; Wu, CS; Yang, C, 2006) |
| "Nosocomial sepsis is a major problem in neonatal units." | ( Coto Cotallo, GD; Crespo Hernández, M; Deschamps Mosquera, EM; Diéguez Junquera, MA; López Sastre, JB; Pérez Solís, D, 2006) |
| "Sepsis is a common and often fatal disease." | ( Andersen, O; Eugen-Olsen, J; Kofoed, K; Scheel, T; Schneider, UV, 2006) |
| "Sepsis is one of the common causes of acute renal failure (ARF)." | ( Dear, JW; Gladwin, MT; Hewitt, SM; Holly, MK; Hu, X; Schechter, AN; Star, RA; Yuen, PS, 2006) |
| "Human sepsis is a spectrum of pathophysiological changes in the host system resulting from a generalized activation and systemic expression of the host's inflammatory pathways in response to infection." | ( Tsokos, M, 2007) |
| "Sepsis is a systemic inflammatory response that results from the inability of the immune system to limit bacterial spread during an ongoing infection." | ( Alves-Filho, JC; Cunha, FQ; Ferreira, SH; Moreno, SE; Rios-Santos, F; Silva, JS; Teixeira, MM, 2006) |
| "Sepsis is the leading cause of death in critically ill patients and the predominant cause of multiple organ failure." | ( Chopin, C; Decoster, B; Favory, R; Hassoun, SM; Lancel, S; Larche, J; Marchetti, P; Neviere, R, 2006) |
| "Sepsis and severe sepsis are accompanied by clinical and laboratory signs of systemic inflammation but patients with inflammation caused by noninfectious causes may present with similar signs and symptoms." | ( Brunkhorst, FM; Meisner, M; Reinhart, K, 2006) |
| "Sepsis is a systemic inflammatory response resulting from local infection due, at least in part, to impaired neutrophil migration." | ( Alfaya, TM; Alves-Filho, JC; da Silva, JS; Ferreira, SH; Liew, FY; Moreno, SE, 2006) |
| "Severe sepsis is a common and commonly fatal disease and is essentially an exaggerated inflammatory response." | ( Nee, PA, 2006) |
| "Sepsis is an infection-induced inflammatory syndrome responsible for approximately 10% of all deaths worldwide." | ( Buckley, JF; Clapp, LH; Singer, M, 2006) |
| "Severe sepsis is accompanied by acute renal failure (ARF) with renal tubular dysfunction and glucosuria." | ( Bucher, M; Höcherl, K; Schmidt, C, 2007) |
| "Sepsis is associated with an increase in reactive oxygen species and low endogenous antioxidative capacity." | ( Abel, P; Angstwurm, MW; Engelmann, L; Gärtner, R; Insel, R; Lehmann, C; Meier-Hellmann, A; Radke, J; Schüttler, J; Spes, CH; Strauss, R; Zimmermann, T, 2007) |
| "Severe sepsis is associated with dysfunction of the macrophage/monocyte, an important cellular effector of the innate immune system." | ( Bu, HF; Hsueh, W; Rozenfeld, RA; Tan, XD; Wang, X; Williams, RY; Zheng, X; Zhu, YQ; Zuo, XL, 2006) |
| "Sepsis is associated with cardiovascular changes that may lead to development of tissue hypoperfusion." | ( Dellinger, RP; Zanotti Cavazzoni, SL, 2006) |
| "Sepsis is a systemic response to infection in which toxins, such as bacterial lipopolysaccharide (LPS), stimulate the production of inflammatory mediators like the cytokine tumor necrosis factor alpha (TNF-alpha)." | ( Acín, S; Amador, P; de la Osada, J; García-Herrera, J; Lostao, MP; Marca, MC; Navarro, MA; Rodríguez-Yoldi, MJ; Salvador, MT, 2007) |
| "The prediction of sepsis is a major and current field of research in the treatment of surgical patients." | ( Bölke, E; Orth, K; Peiper, M; Schulte am Esch, J; Schwarz, A; Spiess, B; Steinbach, G; van Griensven, M; Zant, R, 2007) |
| "Sepsis is a complex disease and is induced by systemic infection of patients suffering from systemic inflammatory response syndromes (SIRS)." | ( Bölke, E; Orth, K; Peiper, M; Schulte am Esch, J; Schwarz, A; Spiess, B; Steinbach, G; van Griensven, M; Zant, R, 2007) |
| "Sepsis is a complex clinical syndrome resulting from a harmful host inflammatory response to infection." | ( Bhatia, M; He, M; Horuk, R; Moochhala, SM, 2007) |
| "Abdominal sepsis is frequently the cause of severe pulmonary dysfunction." | ( Beckert, S; Glatzle, J; Kasparek, MS; Konigsrainer, A; Mayer, P; Meile, T; Mueller, MH; Steurer, W, 2007) |
| "Sepsis is one of the most important risk factors in acute respiratory distress syndrome (ARDS)." | ( Akyurek, N; Bedirli, A; Elbeg, S; Kerem, M; Memis, L; Pasaoglu, H; Sakrak, O; Tezcaner, T, 2007) |
| "Sepsis is characterized physiologically by an aberrant systemic inflammatory response and microvascular dysfunction." | ( Garcia, JG; Jacobson, JR, 2007) |
| "Sepsis is a leading cause of death in the Western world and can be associated with failure of the hypothalamic-pituitary-adrenal axis." | ( Baumgarten, G; Berkels, R; Boehm, O; Bornstein, SR; Kanczkowski, W; Knuefermann, P; Koch, A; Lightman, SL; Schott, M; Tran, N; Zacharowski, K; Zacharowski, PA, 2007) |
| "Severe sepsis is a systemic inflammatory response to infection resulting in acute organ dysfunction." | ( Delsing, AS; Doerschug, KC; Haynes, WG; Schmidt, GA, 2007) |
| "Neonatal sepsis is a disease of infants who are less than 1 month of age." | ( Adib, M; Bakhshiani, Z; Navaei, F; Oreizi, F; Ostadi, V; Saheb Fosoul, F; Shokouhi, R, 2007) |
| "Severe sepsis is the leading cause of death for patients in intensive care units." | ( Antonova, G; Cannon, J; Catravas, JD; Chatterjee, A; Dimitropoulou, C; Drakopanayiotakis, F; Snead, C; Venema, RC, 2007) |
| "Sepsis is the tenth leading cause of death in the U." | ( Barber, A; Davis, B; Fisher, O; Johnson, G; Murphy, P; Pahulu, S; Shires, GT; Williams, S, 2007) |
| "Sepsis is a systemic inflammatory response resulting from the inability of the host to restrict local infection." | ( Alves-Filho, JC; Celes, MR; Cunha, FQ; Dal-Secco, D; Dalto, VF; Ferreira, SH; Freitas, A; Rossi, MA; Spiller, F; Torres-Dueñas, D, 2007) |
| "Severe sepsis is associated with an exacerbated procoagulant state with protein C (PC) system impairment." | ( Aiach, M; Borgel, D; Bornstain, C; Dali-Ali, F; Diehl, JL; Esmon, CT; Fagon, JY; Gandrille, S; Lerolle, N; Reitsma, PH, 2007) |
| "Sepsis is the most common cause of acute kidney injury (AKI) in critical illness, but there is limited information on septic AKI." | ( Bagshaw, SM; Bellomo, R; Bouman, C; Gibney, N; Kellum, JA; Macedo, E; Morgera, S; Morimatsu, H; Oudemans-van Straaten, HM; Ronco, C; Schetz, M; Tan, I; Tolwani, A; Uchino, S, 2007) |
| "Sepsis is a severe condition in critically ill patients and is considered an arginine deficiency state." | ( Deutz, NE; Luiking, YC, 2007) |
| "Sepsis is characterized by severe redox imbalance." | ( Antonione, R; Biolo, G; De Cicco, M, 2007) |
| "Sepsis is associated with major changes in the hypothalamic-pituitary axis." | ( Annane, D; Maxime, V; Siami, S, 2007) |
| "Sepsis is accompanied by an enormous increase in catecholamine expression, leading to metabolism of lipids and glucose, changes in cardiovascular output, immunomodulatory effects, and changes in protein metabolism, all of which push the body into a catabolic state." | ( Herndon, DN; Jeschke, MG; Norbury, WB, 2007) |
| "Sepsis is a major clinical challenge that is associated with encephalopathy and multi-organ dysfunction." | ( Andrews, PL; Brooks, HF; Davies, DC; Moss, RF; Osabutey, CK, 2007) |
| "Sepsis is the most important trigger for acute renal failure, with tubular dysfunction and collapse in urine concentration." | ( Bucher, M; Höcherl, K; Schmidt, C; Schweda, F, 2007) |
| "Sepsis is associated with enhanced generation of reactive oxygen species, which leads to multiple organ dysfunctions." | ( Ercan, F; Gedik, N; Keyer-Uysal, M; Sener, G; Toklu, HZ; Tunali Akbay, T; Velioglu-Ogunc, A, 2008) |
| "Sepsis is of particular importance, as is the lack of enteral nutrition and overfeeding with intravenous glucose and/or lipid." | ( Gabe, SM; Lloyd, DA, 2007) |
| "The pathogenesis of sepsis is mediated in part by bacterial endotoxin, which stimulates macrophages/monocytes to sequentially release early (e." | ( Ashok, M; Li, J; Li, W; Sama, AE; Wang, H; Yang, H, 2007) |
| "Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)." | ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008) |
| "Sepsis is a systemic response to infection, and symptoms are produced by host defense systems rather than by the invading pathogens." | ( Levi, M; Schouten, M; van der Poll, T; Wiersinga, WJ, 2008) |
| "Sepsis is characterized by a systemic response to severe infection." | ( Baron, RM; Chung, SW; Liu, X; Macias, AA; Perrella, MA, 2008) |
| "Sepsis is a complex, multifactorial syndrome that can develop into conditions of different severity, described as septic shock or severe sepsis." | ( Cornelio, DB; Dal-Pizzol, F; Roesler, R; Schwartsmann, G, 2007) |
| "Sepsis is an inflammatory condition that is associated with reduced propulsive gastrointestinal motility (ileus)." | ( d'amico, A; de Filippis, D; de Man, JG; de Winter, BY; Esposito, G; Herman, AG; Iuvone, T; Pelckmans, PA; Steardo, L, 2008) |
| "Sepsis is a complex, incompletely understood and often fatal disorder, typically accompanied by hypotension, that is considered to represent a dysregulated host response to infection." | ( Abrink, M; Chen, CC; Dobner, PR; Faix, JD; Galli, SJ; Metz, M; Mohanasundaram, UM; Nishimura, T; Pearl, RG; Pejler, G; Piliponsky, AM; Rios, EJ; Tsai, M; Wada, E; Wada, K; Zacharias, S, 2008) |
| "Sepsis is a major cause of death in the United States and accounts for approximately 50% of the fatalities in intensive care units." | ( Becker, KL; Christopoulos, A; Christopoulos, G; Nylen, ES; Sexton, PM; Snider, RH, 2008) |
| "Sepsis is a complex clinical syndrome resulting from a harmful host inflammatory response to infection." | ( Bhatia, M; Guglielmotti, A; Ng, SW; Ramnath, RD, 2008) |
| "Severe sepsis is not clinically apparent during the first 24 hours of hospitalization in most children with cancer and febrile neutropenia (FN), delaying targeted interventions that could impact mortality." | ( Alvarez, AM; Aviles, CL; Becker, A; King, A; Mosso, C; O'Ryan, M; Paya, E; Salgado, C; Santolaya, ME; Silva, P; Topelberg, S; Tordecilla, J; Varas, M; Villarroel, M; Viviani, T; Zubieta, M, 2008) |
| "Diagnosis of sepsis is difficult, particularly in cases of burn where signs of sepsis may be present in the absence of a real infection." | ( Alinejad, F; Bahar, MA; Barati, M; Bodouhi, NO; Karimi, H; Shamshiri, AR; Tabrisi, MS, 2008) |
| "Sepsis is associated with impaired PMN function, including chemotaxis." | ( Keshamouni, VG; Milam, JE; Narala, VR; Newstead, MW; Reddy, RC; Standiford, TJ, 2008) |
| "Sepsis is still a major cause of the high mortality rate in the intensive care unit." | ( Ateş, B; Dinckan, A; Esen, H; Kartal, A; Küçükkartallar, T; Tekin, A; Türkyilmaz, S; Yilmaz, H, 2008) |
| "Rapid treatment of sepsis is of crucial importance for survival of patients." | ( Andersen, LH; Andersen, MH; Bestle, M; Bømler, B; Carl, P; Fjeldborg, P; Grarup, J; Hein, L; Hestad, S; Hougaard, S; Jensen, JU; Kjaer, J; Larsen, KM; Lauritsen, AO; Lundgren, B; Lundgren, JD; Løken, J; Mantoni, T; Mohr, T; Ostergaard, C; Petersen, JA; Petersen, PL; Rossau, C; Steensen, M; Søe-Jensen, P; Thomsen, CB; Thormar, K; Thornberg, KJ; Tousi, H, 2008) |
| "Sepsis is characterized by a multitude of pathophysiological changes that include inflammation, metabolic derangements, hemodynamic alterations, and multiorgan dysfunction." | ( Al-Azzawi, D; Crisostomo, PR; Lahm, T; Markel, TA; Meldrum, DR; Novotny, NM; Ray, R; Tan, J; Wang, M; Wang, Y, 2009) |
| "Sepsis is the systemic inflammatory response syndrome secondary to a local infection." | ( Azevedo, LC; Park, M; Schettino, GP, 2008) |
| "Sepsis is a disease with high incidence and lethality and is accompanied by profound metabolic disturbances." | ( Blom, H; Linnebank, M; Moskau, S; Semmler, A; Smith, D; Smulders, Y; Struys, E, 2008) |
| "Sepsis is associated with an increase in SAM/SAH ratio in plasma and CSF in rodents." | ( Blom, H; Linnebank, M; Moskau, S; Semmler, A; Smith, D; Smulders, Y; Struys, E, 2008) |
| "Sepsis is characterised by a systemic dysregulated inflammatory response and oxidative stress, often leading to organ failure and death." | ( Galley, HF; Lowes, DA; Murphy, MP; Thottakam, BM; Webster, NR, 2008) |
| "Sepsis is often associated with systemic intravascular activation of coagulation, potentially leading to widespread microvascular deposits of fibrin, and thereby contributing to multiple organ dysfunction." | ( Levi, M, 2008) |
| "Sepsis is an important cause of mortality in newborns." | ( Akbay, Y; Aksit, MA; Colak, E; Colak, O; Ucar, B; Yarar, C; Yildiz, B, 2008) |
| "Sepsis is a common and serious medical condition caused by hemorrhage, trauma, or abdominal surgery." | ( Chen, X; Sun, BW, 2009) |
| "Animal models of sepsis are still too heterogeneous with regard to type of insult, duration, and supportive therapy to be regarded as representative of the human condition." | ( Dyson, A; Singer, M, 2009) |
| "Sepsis is a leading cause of death in patients with critical illness." | ( Hou, L; Ji, G; Li, N; Lu, Y; Ma, S; Qin, M; Xie, K; Xiong, L, 2009) |
| "The pathogenesis of sepsis is mediated in part by the pathogen-associated molecular pattern molecule bacterial endotoxin, which stimulates macrophages to sequentially release early (e." | ( Kang, R; Lotze, MT; Tang, D; Wang, H; Xiao, W; Xiao, X; Zhang, H, 2009) |
| "Sepsis is the leading cause of death in critically ill patients." | ( An, HJ; Kim, JL; Lee, C; Lee, H; Paik, SG, 2009) |
| "Severe sepsis is frequently associated with hypocholesterolemia which is also a common finding in cirrhotic patients." | ( Chen, PC; Chen, YC; Fang, JT; Lien, JM; Peng, YS; Tian, YC; Tsai, MH; Weng, HH; Wu, CS; Yang, CW, 2009) |
| "Sepsis is the most frequent infection with high mortality rates in intensive care units (ICUs), and the prediction of outcome is important in the decision-making process." | ( Inal, MT; Kargi, M; Memiş, D; Sut, N, 2009) |
| "Sepsis is associated with the development of progressive damage in multiple organ systems." | ( Bayrak, I; Ercan, M; Ozdemir, S; Sunamak, O; Toplan, S; Uruluer, B, 2009) |
| "Sepsis is a leading cause of death that is characterized by uncontrolled inflammatory response." | ( Bernard, P; Daugherty, A; Feng, H; Guo, L; Huang, B; Li, M; Li, XA; Song, Z; Wang, D; Wu, Q, 2009) |
| "Sepsis is defined by the clinical signs of a systemic inflammatory response to infection." | ( Brunner, M; Deitch, EA; Ramos, L; Ulloa, L, 2009) |
| "Sepsis is characterized by an increase in nitric oxide (NO) production, hemodynamic dysfunction and multiple organ failure." | ( Chan, JY; Liu, YC; Tsai, YC, 2009) |
| "Sepsis is a systemic response to an infection that leads to a generalized inflammatory reaction." | ( de Oliveira, JR; de Oliveira, LM; Magrisso, AB; Munhoz, TP; Pires, MG; Roesler, R, 2010) |
| "Sepsis is associated with abnormalities of muscle tissue oxygenation and of microvascular function." | ( Angelopoulos, E; Baraboutis, I; Gerovasili, V; Kritikos, K; Markaki, V; Nanas, S; Poriazi, M; Renieris, P; Roussos, C; Routsi, C; Siafaka, A; Zervakis, D, 2009) |
| "Sepsis is exceedingly burdensome for hospital intensive care unit caregivers, and its incidence, as well as sepsis-related deaths, is increasing steadily." | ( Fortin, CF; Fülöp, T; Lesur, O; McDonald, PP, 2010) |
| "Sepsis is a common and severe complication in premature neonates, particularly those with very low birth weight (VLBW) (<1500 g)." | ( Betta, P; Bollani, L; Bordignon, L; Cattani, S; Decembrino, L; Farina, D; Ferrari, F; Gallo, E; Laforgia, N; Magaldi, R; Magnani, C; Manzoni, P; Maule, M; Memo, L; Messner, H; Mosca, F; Mostert, M; Pedicino, R; Pugni, L; Quercia, M; Renzullo, L; Rinaldi, M; Romeo, MG; Saia, OS; Stolfi, I; Stronati, M; Vagnarelli, F, 2009) |
| "Sepsis is a severe infection-induced systemic inflammatory syndrome." | ( Barratt-Due, A; Castellheim, A; Fosse, E; Fure, H; Hellerud, BC; Johansen, HT; Lindstad, JK; Mollnes, TE; Nielsen, EW; Pharo, A; Thorgersen, EB; Tønnessen, TI, 2010) |
| "Sepsis is an important cause of morbidity and mortality." | ( Rajapakse, S; Wijewickrama, ES, 2009) |
| "Sepsis is a potentially deadly disease that often is caused by gram-positive bacteria, in particular Staphylococcus aureus (S." | ( Amu, S; Andersson, N; Benrick, A; Bokarewa, M; Brisslert, M; Bylund, J; Enge, M; Jansson, JO; Nilsson, S; Onnheim, K; Strandberg, L; Verdrengh, M, 2009) |
| "Sepsis is physiologically viewed as a proinflammatory and procoagulant response to invading pathogens." | ( Durand, F; Gustot, T; Lebrec, D; Moreau, R; Vincent, JL, 2009) |
| "Sepsis is a systemic inflammatory response syndrome (SIRS) when an infection is the etiology of SIRS." | ( Qiang, X; Wang, P; Wu, R; Zhang, F; Zhou, M, 2010) |
| "Sepsis is characterized by systematic inflammation where oxidative damage plays a key role in organ failure." | ( Ceylan-Isik, AF; Ren, J; Su, G; Xiao, X; Zhang, B; Zhao, P, 2010) |
| "Severe sepsis is characterized by relative hypotension associated with a high cardiac output, peripheral vasodilation, and organ dysfunction." | ( Rocco, JR; Salgado, DR; Silva, E; Vincent, JL, 2010) |
| "Sepsis is known to impair endothelium-dependent dilation in the pulmonary vasculature, but the mechanisms are incompletely understood." | ( Arunadevi, R; Kathirvel, K; Leo, MD; Mishra, SK; Prakash, VR; Singh, TU; Subramani, J, 2010) |
| "Sepsis is a severe inflammatory immune response of the host against an infectious agent or its product i." | ( Chhibber, S; Kumar, V, 2009) |
| "Sepsis is a serious complication for patients with obstructive jaundice." | ( Wang, P; Wu, R; Yang, J; Zhou, M, 2010) |
| "Sepsis is characterized by a systemic inflammatory response of the immune system against an infection, presenting with hypothalamic-pituitary-adrenal (HPA) axis dysfunction, behavior alterations, and high mortality." | ( Cassol, OJ; Comim, CM; Constantino, LS; Dal-Pizzol, F; Petronilho, F; Quevedo, J; Streck, EL, 2010) |
| "Sepsis is a systemic host response to infection by pathogenic microorganisms." | ( Mackman, N; Pawlinski, R, 2010) |
| "The pathogenesis of sepsis is characterized by an overwhelming systemic inflammatory response that can lead to multiple organ failure." | ( Cassol, OJ; Dal-Pizzol, F; Ferreira, GK; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Scaini, G; Schwartsmann, G; Streck, EL, 2010) |
| "Sepsis is often associated with cholestatic liver dysfunction caused by changes in the expression profile of hepatic bile salt transporters." | ( Dieudonné, AS; Mesotten, D; Thiessen, S; Van den Berghe, G; van Pelt, J; Van Zwam, K; Vander Borght, S; Wauters, J; Wilmer, A, 2010) |
| "Severe sepsis is a leading cause of death and resource use throughout the world." | ( Nichols, D; Nielsen, ND, 2010) |
| "Sepsis is considered to be the major cause of morbidity and mortality of patients hospitalised in intensive care." | ( Kratochvíl, M; Maláska, J; Muriová, K; Otevrel, F; Sevík, P; Slezák, M, 2010) |
| "Infection and sepsis are major causes of morbidity and mortality after surgery of diabetic patients." | ( Araújo-Filho, I; Azevedo, IM; Egito, ES; Jácome, DT; Medeiros, AC; Rêgo, AC, 2010) |
| "Sepsis is a generalized inflammatory disease, caused by the hyperinflammatory response of the host, rather than by invading organisms." | ( Arai, T; Miyoshi, T; Mizugishi, K; Uchiyama, T; Yamamoto, K; Yamashita, K, 2010) |
| "Sepsis is a leading cause of death, which is characterized by uncontrolled inflammatory response." | ( Feng, H; Fu, W; Gao, H; Guo, L; Han, J; Huang, B; Li, XA; Li, Z; Song, Z; Wang, D, 2010) |
| "Urosepsis is an important complication after percutaneous nephrolithotomy (PNL)." | ( Bag, S; Kumar, S; Mandal, AK; Sharma, V; Singh, SK; Taneja, N, 2011) |
| "Fungal sepsis is an important cause of fever resistant to antibiotic therapy that is very often taken into marginal account." | ( Falzone, E; Guarneri, L; Gugliara, C; Maffeo, F; Pasqua, P; Pulvirenti, F, 2010) |
| "Sepsis is a major cause of mortality worldwide." | ( Cheng, B; Deng, X; Fan, R; Glover, M; Pruett, SB; Tan, W, 2010) |
| "Sepsis is a major health threat that remains refractory to treatment." | ( Goto, K; Hagiwara, S; Iwasaka, H; Koga, H; Kusaka, J; Noguchi, T; Uchida, T; Yokoi, I, 2011) |
| "Bacteremia and sepsis are serious complications of endoscopic retrograde cholangiopancreatography (ERCP) and occur in between 0." | ( Graham, DY; Osato, MS; Ramirez, FC; Woods, KL, 2010) |
| "Sepsis is the systemic inflammatory response syndrome secondary to a local infection, and severe sepsis and septic shock are the more devastating scenarios of this disease." | ( Azevedo, LC; da Silva Ramos, FJ, 2010) |
| "Sepsis is characterized by an excessive host response to infection." | ( Ii, M; Iizawa, Y; Sha, T, 2011) |
| "Sepsis is the systemic inflammatory response to infection and can result in multiple organ dysfunction syndrome with associated high mortality, morbidity and health costs." | ( Sharples, E; Walden, AP; Young, JD, 2010) |
| "Neonatal sepsis is frequently associated with pathological activation of the coagulation system, leading to microcirculatory derangement and multiple organ dysfunction syndrome (MODS)." | ( Abdel-Naim, AB; Adel, M; Al-Azizi, MM; Awad, HA, 2010) |
| "Sepsis is characterized by an intense inflammatory reaction with potential neurotoxic effects in the central nervous system and damage to memory and learning ability." | ( Cassol, OJ; Comim, CM; Constantino, LS; Dal-Pizzol, F; Kapczinski, F; Mango, LA; Quevedo, J; Romano-Silva, MA; Rosa, DV; Stertz, L, 2011) |
| "Sepsis is a syndrome caused by uncontrolled systemic inflammatory response of the individual, which represents a serious epidemiological problem worldwide." | ( Buaes, LE; Caberlon, E; Christ Vianna Santos, R; da Costa, VL; da Silva Melo, DA; da Silva Scherer, P; da Silva, GV; de Mello, RO; de Moraes, CM; de Oliveira, JR; Donadio, MV; Lunardelli, A; Nunes, FB, 2011) |
| "Sepsis is the leading cause of death in critically ill patients in the United States." | ( Shou, J; Wang, Y; Wong, R, 2010) |
| "Sepsis is considered a relative contraindication for epidural blockade." | ( Mohta, M; Seelan, S; Sethi, AK; Tyagi, A, 2011) |
| "Sepsis is a clinical syndrome defined by physiologic changes indicative of systemic inflammation, which are likely attributable to documented or suspected infection." | ( Standage, SW; Wong, HR, 2011) |
| "Sepsis is induced by infectious challenges, and septic organ failure often occurs under local and systemic inflammation." | ( Kamimoto, M; Kato, T; Mizuno, S, 2010) |
| "Neonatal sepsis is one of the most common reasons for admission to neonatal units in developing countries." | ( Abdel-Hady, E; Awad, H; El Hamamsy, M; Hedaya, M, 2011) |
| "Sepsis is a complex multifaceted response to a local infectious insult." | ( Tyml, K, 2011) |
| "Human sepsis is a prototypical inflammatory syndrome, often complicated by the development of anemia." | ( Kroot, JJ; Pickkers, P; Swinkels, DW; Tromp, M; van der Hoeven, JG; van Eijk, LT, 2011) |
| "Sepsis is defined as the systemic inflammatory response to an infection." | ( Calderari, B; Liaudet, L, 2010) |
| "Sepsis is a leading cause of mortality in critically ill patients." | ( Adams, K; Barlow, G; Kibe, S, 2011) |
| "Neonatal sepsis is complicated by pulmonary hypertension." | ( Daoud, GA; Fukuda, S; Goto, T; Hashimoto, T; Hussein, MH; Ito, T; Kakita, H; Kato, I; Kato, S; Mizuno, H; Suzuki, S; Togari, H; Yamaguchi, S, 2011) |
| "Sepsis is a common cause of morbidity and mortality in intensive care units." | ( Barraud, D; Gibot, S, 2011) |
| "Sepsis is a systemic host response to invasive infection by bacteria." | ( Agar, C; de Groot, PG; de Laat, B; Herwald, H; Levels, JH; Meijers, JC; Monk, SD; Mörgelin, M; Urbanus, RT; van der Poll, T; van Os, G, 2011) |
| "The hallmark of sepsis is an overshooting T-cell death that reduces host defense mechanisms and that is associated with poor patient survival." | ( Brüne, B; Kempf, VA; Kuhn, AM; Morbitzer, V; Paulus, P; Schmidt, MV; von Knethen, A; Weigert, A; Zacharowski, K, 2011) |
| "Sepsis is a major health problem in the United States that affects more than three-quarters of a million people every year." | ( Cauvi, DM; Coimbra, R; De Maio, A; Drummond, R; Hawisher, D; Nino, DF; Song, D; Vazquez, DE; Wolf, PL, 2012) |
| "Sepsis is a stressful physical condition, and at the acute phase, overstimulation of the sympathetic nervous system may occur; these events have the potential to induce cardiomyopathy." | ( Karvouniaris, M; Makris, D; Papanikolaou, J; Zakynthinos, E, 2012) |
| "Sepsis is the major cause of death in intensive care units, despite enormous efforts in the development of antimicrobial therapies." | ( Bao, Y; Du, HM; Feng, WM; Tang, CW; Zhu, M, 2011) |
| "Severe sepsis is a systemic inflammatory response to infection that induces organ dysfunction and threatens a person's survival." | ( LaRosa, SP; Tidswell, M, 2011) |
| "Sepsis is defined as a systemic response of organisms to microorganisms and toxins." | ( Ozdemir, S; Sunamak, O; Tanriverdi, G; Toplan, S, 2011) |
| "Sepsis is one of the most cost-intensive conditions of critically ill patients in intensive care medicine." | ( Hochreiter, M; Schroeder, S, 2011) |
| "Sepsis is the most common trigger for acute kidney injury (AKI) in critically ill patients." | ( Bagshaw, SM; Bellomo, R; Bennett, M; Devarajan, P; Haase, M; Haase-Fielitz, A, 2012) |
| "Sepsis is characterized by systemic inflammation with release of a large amount of inflammatory mediators." | ( Dichter, E; Kerner, D; Lacorte, G; Rodriguez, A; Spur, B; Walker, J; Yin, K, 2011) |
| "Sepsis is a disease process that has humbled the medical profession for centuries with its resistance to therapy, relentless mortality, and pathophysiologic complexity." | ( Gatto, L; Golub, LM; Kendrick, D; Nieman, G; Roy, SK; Sadowitz, BD; Satalin, JM; Snyder, K, 2011) |
| "Pseudosepsis is a condition that should be added to these previously described conditions, such as gemcitabine-induced pseudocellulitis." | ( Obeid, KM; Venugopal, AA, 2013) |
| "Sepsis is involved in the decrease of membrane excitability of skeletal muscle, leading to polyneuromyopathy." | ( Arvieux, CC; Gioux, M; Giroux-Metges, MA; Gueret, G; Guillouet, M; Pennec, JP; Rannou, F, 2011) |
| "Severe sepsis is accompanied by oxidative stress and pathological leukocyte endothelial cell interactions." | ( Bogár, L; Csontos, C; Drenkovics, L; Ghosh, S; Lantos, J; Mühl, D; Varga, A; Wéber, G; Woth, G, 2011) |
| "Severe sepsis is a common occurrence in critically ill patients and a major cause of morbidity and mortality in this population." | ( Dimoula, A; Serrano, EC; Vincent, JL, 2011) |
| "Sepsis is a potentially deadly complication that can be caused by different factors." | ( da Rocha, JB; Prauchner, CA; Prestes, Ade S, 2011) |
| "Sepsis is a major cause of death worldwide." | ( Bhatty, M; Jan, BL; Nanduri, B; Pruett, SB; Tan, W, 2011) |
| "Sepsis is associated with defects in renal tubule function, but the underlying mechanisms are incompletely understood." | ( George, T; Good, DW; Sherwood, ER; Watts, BA, 2011) |
| "Sepsis is a systemic immune response to infection that may result in multiple organ failure and death." | ( Baracchi, F; Ingiosi, AM; Opp, MR; Raymond, RM, 2011) |
| "Sepsis is a costly diagnosis in hospitalized patients." | ( Bernstein, LH; Rucinski, J, 2011) |
| "Sepsis is a poorly understood syndrome." | ( Abcejo, A; Andrejko, KM; Deutschman, CS; Ochroch, EA; Raj, NR, 2011) |
| "Sepsis is a systemic inflammatory response to infection and a major cause of morbidity and mortality." | ( Albayrak, A; Atalay, F; Cadirci, E; Ferah, I; Halici, Z; Karakus, E; Odabasoglu, F; Unal, B; Unal, D, 2011) |
| "Sepsis is associated with mitochondrial dysfunction and impaired oxygen consumption, which may condition clinical outcome independent of tissue oxygenation." | ( Cardellach, F; Casademont, J; Garrabou, G; López, S; Miró, O; Morén, C; Tobías, E, 2012) |
| "Sepsis is the clinical syndrome derived from the host response to an infection and severe sepsis is the leading cause of death in critically ill patients." | ( Covajes, C; Donadello, K; Scolletta, S; Vincent, JL, 2012) |
| "The pathogenesis of sepsis is characterized by overwhelming inflammatory responses that lead to tissue damage and organ failure." | ( Kim, TH; Lee, SM; Yoon, SJ, 2012) |
| "Sepsis is a common cause of acute kidney injury (AKI) and acute lung injury." | ( Andrade, L; Campos, R; Canale, D; de Bragança, AC; Lopes, FD; Olivo, C; Seguro, AC; Shimizu, MH; Volpini, RA, 2012) |
| "Mortality of sepsis is still high." | ( Heizmann, P; Heizmann, WR; Lode, H, 2012) |
| "Sepsis is characterized by systemic biochemical alterations including the central nervous system in the early times and cognitive impairment at later times after sepsis induction in the animal model." | ( Abreu, I; Barichello, T; Cassol, OJ; Comim, CM; Constantino, LS; Dal-Pizzol, F; de Rochi, N; Dos Santos Morais, MO; Galant, LS; Moraz, T; Quevedo, J; Scaini, G; Streck, EL; Vuolo, F, 2012) |
| "Sepsis is an inflammatory condition associated with significant morbidity and mortality." | ( O'Neal, HR; Sanchez, MA; Thomas, CB, 2012) |
| "Sepsis is a deadly and costly condition with no available, specific treatment options." | ( O'Neal, HR; Sanchez, MA; Thomas, CB, 2012) |
| "Sepsis is characterized by an initial systemic proinflammatory response leading to endothelial damage and increased capillary permeability." | ( Drumheller, BC; Gaieski, DF; Matsuura, AC; McGrath, M, 2012) |
| "Sepsis is associated with high morbidity and mortality, and survivors can present with cognitive dysfunction." | ( Bai, YP; Chen, Y; Huang, GQ; Li, J; Liu, L; Wang, J; Wu, GM; Zhou, J, 2012) |
| "Although sepsis is a major cause of morbidity and mortality among newborns in resource-poor countries, little data are available from rural areas on culture-proven sepsis." | ( Basu, S; Dasgupta, S; Ghosh, C; Mukherjee, S; Singh, AK; Viswanathan, R, 2012) |
| "Sepsis is an increasingly prevalent cause of death, and management in the early stage is a critical issue." | ( Cavalcanti, P; Giraldi, C; Mauro, MV; Noto, A; Perugini, D; Sperlì, D, 2012) |
| "Sepsis is a severe disorder characterized by systemic inflammatory responses in the presence of an infection and may progress to multiple organ dysfunction and death." | ( Araújo, CV; Bozza, PT; Castro-Faria-Neto, HC; Estato, V; Silva, AR; Tibiriçá, E, 2012) |
| "Inflammation in sepsis is associated with hypercoagulation that may lead to thrombosis and disseminated intravascular coagulation." | ( Ataullakhanov, FI; Balandina, AN; Fadeeva, OA; Galstian, GM; Karamzin, SS; Kretchetova, AV; Panteleev, MA; Soshitova, NP, 2012) |
| "Neonatal sepsis is common and is a major cause of morbidity and mortality." | ( Allegaert, K; Pacifici, GM, 2012) |
| "Neonatal sepsis is a major cause of neonatal deaths in Asia but data remain scarce." | ( Al-Taiar, A; Cuiqing, L; Hammoud, MS; Isaacs, D; Lee, JK; Lui, KM; Nakwan, N, 2013) |
| "Sepsis is a systemic inflammatory response syndrome with a suspected or proven infection caused by any pathogen or a clinical syndrome associated with a high probability of infection." | ( Buharalioglu, CK; Falck, JR; Kacan, M; Korkmaz, B; Malik, KU; Sahan-Firat, S; Sari, AN; Schunck, WH; Serin, MS; Tunctan, B; Unsal, D, 2012) |
| "Sepsis is associated with impaired muscle function but the role of glucocorticoids in sepsis-induced muscle weakness is not known." | ( Alamdari, N; Aversa, Z; Castillero, E; Hasselgren, PO; Jasuja, R; Larsson, L; Qaisar, R; Renaud, G; Smith, I; Toraldo, G, 2012) |
| "Sepsis is associated with systemic inflammatory responses and induction of coagulation system." | ( Apostolidou, E; Chrysanthopoulou, A; Girod, A; Kambas, K; Koffa, M; Kotsianidis, I; Kourtzelis, I; Mitroulis, I; Pneumatikos, I; Ritis, K; Skendros, P, 2012) |
| "Sepsis is a frequent complication in critical illness." | ( Breuel, KF; Ferguson, DA; Ford, TR; Ha, T; Kalbfleisch, J; Kelley, JL; Li, C; Ozment, TR; Schweitzer, JB; Williams, DL, 2012) |
| "Sepsis is one of the leading causes of death in the critically ill." | ( Sankar, V; Webster, NR, 2013) |
| "Sepsis is a potentially life-threatening condition that requires urgent management in an Emergency Department (ED)." | ( Bond, CM; Bullard, MJ; Djogovic, D; Meurer, DP; Rowe, BH; Villa-Roel, C, 2013) |
| "Sepsis is a potentially lethal systemic inflammatory reaction to a local bacterial infection, affecting thousands of patients annually." | ( Bodkin, JV; Fernandes, ES, 2013) |
| "Sepsis is the most common cause of death in intensive care units." | ( Chen, H; Fu, W; Han, H; Li, A; Wang, G; Xie, K; Xing, W; Yu, Y, 2012) |
| "Sepsis is a complex, multifactorial, rapidly progressive disease characterized by an overwhelming activation of the immune system and the countervailing antiinflammatory response." | ( Lee, CH; Lee, SM; Yoon, SJ, 2013) |
| "Sepsis is a major clinical challenge and septic encephalopathy is its nasty complication." | ( Chiba, S; Hattori, Y; Sagara, H; Takano, Y; Takashina, M; Tomita, K; Yagisita, S; Yokoo, H, 2012) |
| "Gram-negative sepsis is accompanied by a disproportionate innate immune response and excessive coagulation mainly induced by endotoxins released from bacteria." | ( Albiger, B; Kalle, M; Kasetty, G; Malmsten, M; Mörgelin, M; Papareddy, P; Rydengård, V; Schmidtchen, A; van der Plas, MJ, 2012) |
| "Severe sepsis is a condition with a high mortality rate, and the majority of patients are first seen by Emergency Medical Services (EMS) personnel." | ( Clouatre, AE; Guerra, WF; Mayfield, TR; Meyers, MS; Riccio, JC, 2013) |
| "Sepsis is associated with a variety of defects in renal tubule function, but the underlying mechanisms are incompletely understood." | ( George, T; Good, DW; Sherwood, ER; Watts, BA, 2013) |
| "Puerperal sepsis is a leading cause of maternal mortality worldwide." | ( Aronoff, DM; Faccioli, LH; Mason, KL; Rogers, LM; Serezani, CH; Soares, EM, 2013) |
| "Severe sepsis is associated with a high mortality rate despite implementation of guideline recommendations." | ( Chen, J; Chen, L; Chen, M; Chen, Y; Gu, B; Guan, X; He, Z; Kou, Q; Li, Y; Lin, A; Liu, J; Ma, G; Ou-Yang, B; Qiang, X; Wu, J; Wu, X; Zhang, G; Zhou, L; Zou, Z, 2013) |
| "Sepsis is a leading healthcare problem, accounting for the vast majority of fatal events in critically ill patients." | ( Avanzi, GC; Cervellin, G; Di Somma, S; Fiotti, N; Hein, F; Lalle, I; Lippi, G; Lupia, E; Magrini, L; Maisel, A; Travaglino, F; Wagner, F, 2013) |
| "coli sepsis are characterized by an association of Trem-1 expression on blood neutrophils with cytokine inducibility." | ( Dalhoff, K; Dodt, C; Drömann, D; Goldmann, T; Luitjens, K; Schaaf, B; van Bremen, T, 2013) |
| "Klebisella ozaenae sepsis is rarely reported in medical literature." | ( Al Khalloufi, K; Endailalu, YW; Michael, M; Nabhani, H; Sealy, P, 2012) |
| "Severe sepsis is a major problem as cause of high rates morbidity and mortality in intensive care units (ICU)." | ( Ahmadi, A; Mahmoudi, L; Mohammadpour, AH; Mojtahedzadeh, M; Niknam, R, 2013) |
| "The diagnosis of sepsis is difficult in immunocompromised patients owing to their modified response to infection." | ( Cap, J; Gürlich, R; Kieslichova, E; Kudla, M; Merta, D; Rocen, M; Splichal, I; Viklicky, O, 2013) |
| "Sepsis is the systemic response of an organism against microorganisms and toxins." | ( Albayrak, A; Atamanalp, SS; Bayir, Y; Cadirci, E; Halici, Z; Karakus, E; Karcioglu, SS; Kunak, S; Polat, B; Unal, D; Yigit, S, 2013) |
| "A key tissue in sepsis is the endothelium, which expresses TLR2 and TLR4 receptors, known regulators of inflammatory mechanisms and potential therapeutic targets for this pathology." | ( Álvarez, J; Baluja, A; Brea, D; Rodríguez, A; Rodríguez, J; Rodríguez-González, R; Taboada, M; Veiras Del Río, S, 2013) |
| "Sepsis is a serious medical condition that is characterized by a whole-body inflammatory state and the presence of a known or suspected infection." | ( Bayir, Y; Bilgin, BC; Cadirci, E; Halici, Z; Polat, B; Unal, D; Vancelik, S; Yuksel, TN, 2013) |
| "Since sepsis is more severe in older animals or patients, we tested whether EPO was renoprotective in 8-month-old wild-type and βcR knockout mice that underwent cecal ligation and puncture." | ( Brines, M; Cerami, A; Coldewey, SM; Collino, M; Hall, P; Kapoor, A; Khan, AI; Kieswich, JE; Patel, NS; Rogazzo, M; Sheaff, M; Thiemermann, C; Yaqoob, MM, 2013) |
| "Sepsis is a serious worldwide health care condition that is associated with high mortality rates, despite improvements in the ability to manage infection." | ( Aitken, L; Kleinpell, R; Schorr, CA, 2013) |
| "Sepsis is known to affect neuroendocrine circuits: injections of lipopolysaccaride are potent stimulators of oxytocin secretion from the posterior lobe, acute sepsis leads to uterus contractions and spontaneous abort." | ( Jirikowski, GF; Kafa, IM; Schäfer, HH; Sendemir, E, 2013) |
| "Sepsis is a complex pathophysiological event involving metabolic acidosis, systemic inflammatory response syndrome, tissue damage and multiple organ dysfunction syndrome." | ( Aksak, S; Albayrak, A; Atamanalp, SS; Bayir, Y; Cadirci, E; Gundogdu, C; Halici, Z; Karakus, E; Polat, B; Unal, D, 2013) |
| "Sepsis is caused by an overwhelming immune response to bacterial infection." | ( Cao, L; Kang, R; Tang, D; Xie, M; Yang, L; Yang, M; Yu, Y; Zhao, M, 2013) |
| "Severe sepsis is one of the leading causes of acute kidney injury (AKI)." | ( Hovilehto, S; Inkinen, O; Kaminski, T; Karlsson, S; Kaukonen, KM; Korhonen, AM; Laru-Sompa, R; Lund, V; Pettilä, V; Poukkanen, M; Reinikainen, M; Vaara, ST, 2013) |
| "Sepsis is characterized by a generalized inflammatory response and organ failure, associated with mitochondrial dysfunction." | ( Aslami, H; Beurskens, CJ; Bos, AP; Juffermans, NP; Kerindongo, RP; Kuipers, MT; Kulik, W; Pulskens, WP; Roelofs, JJ; Roelofsen, J; Schultz, MJ; van Kuilenburg, AB; Wanders, RJ; Weber, NC, 2013) |
| "Sepsis is a severe complication of critically ill patients that is characterized by the systemic inflammatory response syndrome (SIRS)." | ( Fan, S; Li, N; Liu, H; Xing, J; Zhang, Y, 2013) |
| "Sepsis is an important cause of neonatal death and perinatal brain damage, particularly in preterm infants." | ( Aktaş, A; Aliefendioglu, D; Çağlayan, O; Gürsoy, T; Ovalı, F, 2014) |
| "Sepsis is an acute inflammatory condition that can result in multiple organ failure and acute lung injury." | ( Coppa, GF; Giangola, MD; Nicastro, J; Rajayer, SR; Wang, P; Yang, WL, 2013) |
| "Sepsis is the leading cause of death in Chinese paediatric AKI patients." | ( Cao, Y; Dang, XQ; Huang, AW; Wu, XC; Yi, ZW; Zhang, H, 2013) |
| "Sepsis is associated with systemic inflammatory responses and induction of intravascular fibrin formation." | ( Abrams, ST; Downey, C; Ken-Dror, G; Toh, JM, 2013) |
| "Sepsis is one of the most common causes of mortality in intensive care units." | ( Ni, YL; Wang, GB; Zhang, WF; Zhou, XP, 2014) |
| "Sepsis is characterized as an uncontrolled inflammatory response." | ( Bao, R; Bo, LL; Chen, F; Deng, XM; Fan, XH; Li, JB; Wang, F; Wu, YP; Zhu, JL, 2014) |
| "Diagnosing sepsis is difficult in burn patients because of the inflammatory mediators that alter postburn metabolic profile." | ( Akbaba, D; Benzonana, N; Cakır Madenci, Ö; Orçun Kaptanağası, A; Yakupoğlu, S; Yücel, N, 2014) |
| "Sepsis is the third most common cause of neonatal death, with Group B Streptococcus (GBS) being the leading bacterial agent." | ( Alves, J; Andrade, EB; Cordeiro-da-Silva, A; Correia-Neves, M; Ferreira, P; Madureira, P; Oliveira, L; Ribeiro, A; Trieu-Cuot, P, 2013) |
| "Sepsis is characterized by systemic immune activation and neutrophil-mediated endothelial barrier integrity compromise, contributing to end-organ dysfunction." | ( Cioffi, WG; Fox, ED; Heffernan, DS; Reichner, JS, 2013) |
| "Since pediatric sepsis is a significant health problem, which differs in epidemiology and pathophysiology from sepsis in adults, and because of the scarcity of data in this population, studies focused on pathophysiological mechanisms and possible interventions in arginine metabolism in pediatric critical illness are warranted." | ( de Betue, CT; Deutz, NE, 2013) |
| "Sepsis is difficult to diagnose and remains a common mortality cause worldwide in both humans and animals." | ( Ambrosen, A; Hagman, R; Karlsson, I; Kindahl, H; Södersten, F; Wang, L; Wernersson, S, 2013) |
| "Neonatal sepsis is a significant cause of morbidity and mortality among term and preterm infants." | ( Attar, M; Bradford, L; Harrison, C; Hasvold, J; Nelson, C; Stillwell, T, 2013) |
| "Sepsis is defined as systemic inflammatory response syndrome (SIRS) in the context of an underlying infectious process, and is associated with high rates of morbidity and mortality, particularly when initial therapy is delayed." | ( Chamberlain, RS; Sridharan, P, 2013) |
| "Sepsis is the complex syndrome characterized by an imbalance between proinflammatory and antiinflammatory response to infection." | ( Dal-Pizzol, F; de Castro, AA; Quevedo, J; Steckert, AV, 2014) |
| "Sepsis is a major cause of mortality, and dysregulation of the immune response plays a central role in this syndrome." | ( Colombani, PM; Ferlito, M; Fox-Talbot, K; Fulton, WB; Marchionni, L; Paolocci, N; Steenbergen, C; Wang, Q, 2014) |
| "Neonatal sepsis is a disease affecting newborns ≤1 month of age with clinical symptoms and positive blood cultures." | ( Bosch, J; Guiral, E; López, Y; Montero, I; Sáez-López, E; Soto, SM; Vila, J, 2014) |
| "Sepsis is defined as an uncontrolled inflammatory response in a host." | ( Fadillioglu, E; Karaman, A; Ozturk, E; Samdancı, E; Surucu, M, 2014) |
| "Sepsis is a life-threatening infection." | ( Boury, M; Cuevas-Ramos, G; Marcq, I; Martin, P; Nougayrède, JP; Olier, M; Oswald, E; Payros, D; Watrin, C, 2014) |
| "Sepsis is a systemic inflammatory condition resulting from bacterial infections; it has a high mortality rate and limited therapeutic options." | ( Bae, JS; Kim, IS; Kim, JE; Kim, SW; Lee, W; Nam, JO, 2014) |
| "Sepsis is the leading cause of death in the intensive care units worldwide." | ( Cui, Y; Gao, Y; Hou, M; Jin, H; Song, Z; Yang, H, 2014) |
| "Sepsis is a global health problem." | ( Hernández P, G; Romero P, C, 2013) |
| "In the ED, sepsis is a relevant cause of elevated cTn, which underlines the role of sepsis as a differential diagnosis in non-ACS patients with positive cTn." | ( Amoury, M; Bagger, S; Ebelt, H; Gerhardt, F; Hettwer, S; Mundt, S; Muschik, S; Schuermann, M; Werdan, K; Wilhelm, J; Zimmermann, J, 2014) |
| "Sepsis is defined as systemic inflammatory response syndrome that occurs during infection." | ( Annecke, T; Caldwell, CC; Conzen, P; Huber, N; Johnson, BL; Martignoni, A; Schlag, C; Siegl, D; Tschöp, J, 2014) |
| "Sepsis is a massive inflammatory response mediated by infection, characterized by oxidative stress, release of cytokines, and mitochondrial dysfunction." | ( Allen, L; Aucott, LS; Cameron, G; Galley, HF; Lowes, DA; Webster, NR, 2014) |
| "Sepsis is a state of disrupted inflammatory homeostasis that is initiated by infection." | ( Bae, JS; Han, MS; Kim, KM; Ku, SK; Yoo, H, 2014) |
| "Sepsis is a deleterious systemic response to an infection with a high incidence of morbidity and mortality, affecting more than a million patients a year in the US." | ( Goerlich, CE; Holcomb, JB; McCarthy, JJ; Moore, LJ; Wade, CE, 2014) |
| "Sepsis is a serious infection and still a common cause of morbidity and mortality in resource-limited settings such as India." | ( Gupta, A; Mave, V; Nelson, GE, 2014) |
| "Sepsis is a complex condition that results from a dysregulated immune system in response to a systemic infection." | ( Kelly, ME; Lehmann, C; Sardinha, J; Zhou, J, 2014) |
| "Sepsis is characterized by a severe inflammatory response to infection." | ( Liu, L; Wang, G; Xie, K; Yu, Y, 2014) |
| "Sepsis is a systemic inflammatory response to infection, and early responses of macrophages are vital in controlling the infected microorganisms." | ( Gao, X; Li, Y; Ma, X; Shao, B; Wang, Z; Wei, Y; Xu, G; Zhang, B, 2014) |
| "Even though sepsis is also a leading cause of death in foals and adult horses, up to now, no data about the role of equine PCT in septic horses has been available." | ( Barton, AK; Geerlof, A; Gehlen, H; Hartmann, A; Kochleus, C; Kremmer, E; Rascher, D; Rieger, M; Schmid, M; Teschner, D, 2014) |
| "Sepsis is often initiated by invasive infection, characterized by overwhelming induction of pro-inflammatory cytokines." | ( Fu, J; Ji, K; Li, G; Luan, T; Zang, B; Zhao, Y, 2015) |
| "Sepsis is characterized by a severe systemic inflammatory response to infection that is associated with high morbidity and mortality despite optimal care." | ( Anantha, RV; Fraser, DD; Haeryfar, SM; Martin, CM; Mazzuca, DM; McCormick, JK; Mele, T; Porcelli, SA; Welch, I; Xu, SX, 2014) |
| "Sepsis is strongly associated with patency of the ductus arteriosus (PDA) in critically ill newborns." | ( Brown, N; Clark, RH; Cotton, RB; Ehinger, NJ; Goettel, JA; Paria, BC; Poole, SD; Reese, J; Rojas, MA; Shelton, EL; Slaughter, JC; Vucovich, MM; Wynn, JL, 2014) |
| "Sepsis is one of the leading causes of mortality in critically ill patients, and providing a timely diagnosis and early intervention is necessary for successful treatment." | ( Fujisiro, M; Haruki, K; Hitani, A; Mizuguchi, M; Nakajima, A; Sagara, H; Shibazaki, M; Sugiki, D; To, M; Yazawa, J, 2014) |
| "Sepsis is a common disease that continues to increase in incidence in the world." | ( Cai, J; Deng, YP; Jiang, GJ; Lu, S; Ren, GF; Shen, FM; Yao, Z; Yu, JW; Zhang, LD, 2014) |
| "Sepsis is one of the most serious and life-threatening clinical conditions of childhood." | ( Celik, M; Cengiz, AB; Ceyhan, M; Hascelik, G; Kara, A; Karadag-Oncel, E; Ozkaya-Parlakay, A; Ozsurekci, Y, 2014) |
| "Late onset neonatal sepsis is one of the major clinical concerns when premature babies receive intensive care." | ( Freer, Y; Stanculescu, I; Williams, CK, 2014) |
| "Sepsis is a systemic inflammatory response syndrome resulting from a microbial infection." | ( Bae, JS; Kim, IS; Lee, W; Lee, YM; Son, HN, 2014) |
| "Sepsis is a complex medical condition characterized by a systemic inflammatory response in the setting of infection." | ( Bellevue, O; Brown, I; Harris, HW; Kasravi, S; Lee, M; Lyo, V; Rayikanti, B; Shawo, A; Uzosike, ED; Woldesemayat, H, 2015) |
| "Sepsis is a major cause of acute kidney injury (AKI) with high rates of morbidity and mortality." | ( Abdel-Razek, O; Cooney, RN; Hu, F; Liu, J; Liu, Z; Wang, G; Zhou, Q, 2015) |
| "Neonatal sepsis is a major cause of neonatal mortality." | ( Gill, CJ; Guerina, NG; Hamer, DH; Knapp, AB; MacLeod, WB; Mirochnick, M; Phiri-Mazala, G, 2014) |
| "Severe sepsis is a major cause of mortality among critically ill patients." | ( Hankins, GD; Pacheco, LD; Saade, GR, 2014) |
| "Sepsis is a severe systemic inflammatory disorder that rapidly activates the sympathetic nervous system to enhance catecholamine secretion from postganglionic sympathetic neurons and adrenal chromaffin cells." | ( Lomax, AE; Lukewich, MK, 2015) |
| "Sepsis is characterized as a systemic inflammatory response syndrome during infection, which can result in multiple organ dysfunction and death." | ( Gao, P; Gu, Z; Hu, Z; Sun, M; Yang, Q; Yuan, Y; Zhang, K, 2015) |
| "Mortality in sepsis is most often attributed to the development of multiple organ failure." | ( Botero-Quintero, AM; Darwiche, S; Escobar, DA; Gomez, H; Kautza, BC; Loughran, P; Luciano, J; Rosengart, MR; Zuckerbraun, BS, 2015) |
| "Sepsis is a systemic inflammatory response syndrome induced by infection." | ( Bi, HL; Du, JJ; Li, Y; Sun, MR; Sun, YH; Wu, CL; Wu, QY; Zeng, JY, 2015) |
| "Sepsis is characterized by a severe production of reactive oxygen species (ROS) and other radical species with consequent oxidative stress." | ( Akyuz, F; Aydın, O; Bayraktar, O; Burukoglu, D; Musmul, A; Tekin, N, 2015) |
| "It seems that if sepsis is recognized early, a rapid initiation of antibiotics and adequate fluid resuscitation are more important than measuring venous oxygen saturation." | ( Bloos, F; Hartog, C, 2014) |
| "Sepsis is a rare but severe complication after haemorrhoid treatment." | ( Lind, M; Poulsen, J; Vejlby, A, 2014) |
| "Abdominal sepsis is associated with significant changes in systemic inflammation and coagulation." | ( Braun, OÖ; Norström, E; Thorlacius, H; Wang, Y; Zhang, S, 2015) |
| "Sepsis is a state of infection with serious systemic manifestations, and if severe enough, can be associated with multiple organ dysfunction and systemic hypotension, which can cause tissues to be hypoxic." | ( Hirota, K, 2015) |
| "Sepsis is characterized by an overwhelming systemic inflammation and multiple organ injury." | ( Dong, S; Duan, J; Fan, D; Lei, L; Li, J; Liang, Q; Liu, J; Zhang, J, 2015) |
| "Sepsis is associated with acute lung injury (ALI) and high mortality." | ( Chen, Y; Liu, L; Mo, LQ; Mou, M; Ren, CH; Wu, GM; Zhou, J, 2015) |
| "Sepsis is a common cause of acute kidney injury (AKI) and is associated with substantial morbidity and mortality." | ( Balaganur, V; Begum, J; Bhat, RA; Kandasamy, K; Kumar, D; Lingaraju, MC; Pathak, NN; Ram, M; Ramachandra, HD; Singh, V; Tandan, SK, 2015) |
| "Neonatal sepsis is a major cause of morbidity and mortality and its signs and symptoms are nonspecific, which makes the diagnosis difficult." | ( Celes, MR; Corrêa, RR; da Silva, MV; de Menezes, LB; dos Reis, MA; Etchebehere, RM; Machado, JR; Monteiro, ML; Soave, DF, 2014) |
| "Sepsis is one of the main causes of mortality in severe burns." | ( Han, C; Hu, H; Li, Y; Ren, H, 2015) |
| "ESBL Gram-negative sepsis is a substantial problem in neonatal infections." | ( Dasi, T; Kumar, C; Murki, S; Pandita, A; Pratap, OT; Sharma, D, 2016) |
| "Sepsis is a severe pathologic event, frequently causing death in critically ill patients." | ( Abe, N; Aibiki, M; Choudhury, ME; Kawasaki, S; Kikuchi, S; Kuwabara, J; Nagaro, T; Nishihara, T; Takahashi, H; Tanaka, J; Watanabe, Y; Yano, H, 2015) |
| "Sepsis is a generalized, usually infectious disease with a complex dsyregulated immune response and capillary leak." | ( Köhler, D, 2015) |
| "Sepsis is a life threatening condition that arises when the body's response to an infection injures its own tissues and organs." | ( Baranyi, M; Bender, B; Bodrogi, L; Bösze, Z; Brands, R; Kerekes, A; Uhrin, P, 2015) |
| "Sepsis is a life threatening condition resulting from a high burden of infection." | ( Ahmed, SM; Chandrasekar, B; Deobagkar-Lele, M; Gautam, R; Kumar, S; Majumdar, S; Nandi, D; Sundaresan, NR; Umapathy, S; Verma, T; Victor, E; Wadhwa, N, 2016) |
| "Sepsis is associated with an increase in reactive oxygen species (ROS), however, the precise role of ROS in the septic process remains unknown." | ( Ghouleh, IA; Magder, S; Parthenis, DG, 2015) |
| "Sepsis is a potentially fatal whole-body inflammation caused by severe infection." | ( Chen, H; Li, Y; Wang, G; Xie, K; Yu, Y, 2015) |
| "Sepsis is a serious problem in intensive care units all over the world." | ( Godnic, M; Jukic, T; Skvarc, M; Stubjar, D; Stubljar, D, 2015) |
| "Sepsis is a common disease seen in critically ill patients." | ( Fremont, RD; Rice, TW, 2015) |
| "Sepsis is an important cause of worldwide morbidity and mortality." | ( Barlow, G; Hilliard, H; Rowland, T, 2015) |
| "Severe sepsis is associated with approximately 50% mortality and accounts for tremendous healthcare costs." | ( Beck-Schimmer, B; Bonini, MG; Dull, RO; Mao, M; Minshall, RD; Piegeler, T; Schläpfer, M; Schwartz, DE; Z'Graggen, BR, 2015) |
| "Sepsis is a significant public healthcare problem, affecting millions of people worldwide each year, killing one in four, and increasing in incidence." | ( Fei, J; Liu, Q; Wang, H; Wang, J; Wang, S; Zhu, R, 2015) |
| "The severity of sepsis is significantly affected by advanced age; however, age-dependent molecular mechanisms of this susceptibility are unknown." | ( Botez, G; Cook, JA; Hake, PW; Ledford, JR; O'Connor, M; Piraino, G; Zingarelli, B, 2015) |
| "Sepsis is a life threatening disease that is associated with high mortality." | ( Arvapalli, R; Asano, S; Blough, ER; Fankhanel, E; Ma, JJ; Maheshwari, M; Manne, ND; Nepal, N; Rice, KM; Rogers, S; Selvaraj, V; Shokuhfar, T, 2015) |
| "Sepsis is characterized by systemic activation of coagulation and inflammation in response to microbial infection." | ( Dwivedi, DJ; Fox-Robichaud, AE; Gould, TJ; Gross, PL; Khan, M; Liaw, PC; Mai, SH; Ross, CA; Weitz, JI; Zhou, J, 2015) |
| "Sepsis is the predominant cause of mortality in ICUs, and opioids are the preferred analgesic in this setting." | ( Banerjee, S; Li, D; Ma, J; Meng, J; Roy, S; Sindberg, GM; Wang, F, 2015) |
| "Sepsis is one of the leading causes of mortality in severe systemic inflammatory syndrome." | ( Jiao, XF; Li, JX; Wang, XW; Zhang, K, 2015) |
| "Sepsis is a systemic inflammatory response to infection that causes severe neurological complications." | ( An, R; Li, X; Lin, Y; Liu, H; Qu, Y; Reiter, RJ; Yang, X; Yang, Y; Yue, L; Zhao, L, 2015) |
| "Severe sepsis is defined by organ failure, often of the kidneys, heart, and brain." | ( Andersen, KK; Granfeldt, A; Gutiérrez-Lizardi, P; Iversen, NK; Jensen, MS; Jespersen, SN; Mouridsen, K; Nagenthiraja, K; Secher, N; Tietze, A; Tønnesen, EK; Østergaard, L, 2015) |
| "Sepsis is a complex syndrome with high mortality, which often induces acute lung injury (ALI) and acute respiratory distress syndrome." | ( Dai, H; Fu, J; Li, B; Meng, X; Wu, L; Yan, X; Zheng, Y, 2015) |
| "Sepsis is a serious, life-threatening, infectious disease." | ( Bae, YS; Choi, YW; Ko, MJ; Lee, HY; Lee, SK; Park, YJ; Wang, Z, 2015) |
| "Sepsis is associated with oxidative stress." | ( Bogár, L; Csontos, C; Kátai, E; Kun, S; Lantos, J; Miseta, A; Molnár, GA; Szélig, L; Wittmann, I; Woth, G; Zrínyi, Z, 2016) |
| "Sepsis is still a major cause of death and many efforts have been made to improve the physical condition of sepsis patients and to reduce the high mortality rate associated with this disease." | ( Barcena Varela, S; Brandenburg, K; Drömann, D; Ferrer-Espada, R; Goldmann, T; Gutsmann, T; Heinbockel, L; Martinez de Tejada, G; Marwitz, S; Mier, W; Reiling, N; Schürholz, T, 2015) |
| "Sepsis is a life-threatening acute inflammatory condition associated with metabolic complications." | ( Coppa, GF; Corbo, L; Idrovo, JP; Jacob, A; Nicastro, J; Wang, P; Yang, WL, 2016) |
| "Prematurity and sepsis are the major contributors of neonatal mortality and neurodevelopmental sequelae." | ( Agarwal, P; Anupurba, S; Basu, S; Kumar, A; Shukla, R, 2015) |
| "Sepsis is the systemic inflammatory response to an infection." | ( Colp, P; Holbein, BE; Islam, S; Jarosch, S; Lehmann, C; Parquet, Mdel C; Toguri, JT; Zhou, J, 2016) |
| "Sepsis is the host's deleterious systemic inflammatory response to microbial infections." | ( Billiar, TR; Chai, X; Deng, M; Fan, J; Fu, H; Gaikwad, NW; Guo, Y; Hu, B; Huang, M; Jiang, M; Kucera, HR; Li, Z; Liu, Y; Lu, P; Xie, W; Xu, M; Yan, J; Yu, L; Zeng, S, 2015) |
| "Sepsis is still a major cause of morbidity and mortality despite the improvements in diagnosis and treatment." | ( Cevval, U; Çiğdem Banu, Ç; Gönül, DH; Halim, B; Melek, Ç; Münip Hakan, Y; Özlem, T, 2015) |
| "Sepsis is a life-threatening condition caused by the systemic inflammatory response to a bacterial infection." | ( Bourque, CW; Prager-Khoutorsky, M; Sharshar, T; Siami, S; Stare, J; Trudel, E, 2015) |
| "Sepsis is a life-threatening condition caused by the systemic inflammatory response to bacterial infection." | ( Bourque, CW; Prager-Khoutorsky, M; Sharshar, T; Siami, S; Stare, J; Trudel, E, 2015) |
| "When sepsis is accompanied by conditions in which systemic oxygen delivery does not meet tissue oxygen demands, tissue hypoperfusion begins." | ( Disselkamp, M; Gill, J; Jaehne, AK; Rivers, EP; Yataco, AC, 2015) |
| "Sepsis is accompanied by severe metabolic alterations." | ( Chang, J; Chung, KS; Jung, JY; Jung, WJ; Kang, YA; Kim, EY; Kim, SK; Kim, SY; Kim, YS; Lee, IS; Lee, SH; Park, BH; Park, MS, 2015) |
| "Sepsis is a lethal and complex clinical syndrome caused by infection or suspected infection." | ( Dong, H; Huang, J; Li, J; Lv, J; Zhong, Y; Zhou, Y, 2015) |
| "Sepsis is a major clinical challenge in modern medicine, representing one of the leading causes of death in developed countries." | ( Jiang, H; Liu, R; Tian, Y; Wu, X; Zhao, W, 2016) |
| "Although sepsis is caused in more than 50% cases by Gram-positive and mycoplasma cells, the causative compounds are still poorly described." | ( Alexander, C; Bárcena-Varela, S; Brandenburg, K; Correa, W; Ferrer-Espada, R; Fukuoka, S; Gisch, N; Goldmann, T; Gutsmann, T; Heinbockel, L; Heine, H; Martinez de Tejada, G; Sánchez-Gómez, S; Schürholz, T; Wiesmüller, KH, 2015) |
| "Sepsis is a severe inflammatory disease resulting in excessive production of pro-inflammatory cytokines including interleukin-6 (IL-6), causing oxidative stress, tissue damage and organ dysfunction." | ( Becker, NP; Hybsier, S; Martitz, J; Renko, K; Schomburg, L; Stoedter, M, 2015) |
| "Sepsis is a life threatening condition that is characterized by the loss of vascular reactivity." | ( Arvapalli, R; Asano, S; Blough, ER; Ma, B; Manne, ND; Nandyala, G; Rice, KM; Selvaraj, V, 2015) |
| "Sepsis is the commonest cause of acute kidney injury in critically ill patients." | ( Chan, TM; Shum, HP; Yan, WW, 2016) |
| "Bacteria-induced sepsis is a common cause of pulmonary endothelial barrier dysfunction and can progress toward acute respiratory distress syndrome." | ( Nickols, J; Obiako, B; Putinta, K; Ramila, KC; Sayner, SL; Schilling, S, 2015) |
| "Sepsis is characterized by systemic activation of inflammation and coagulation in response to infection." | ( Dwivedi, DJ; Fox-Robichaud, AE; Gould, TJ; Kim, PY; Liaw, PC; Stafford, AR; Vu, TT; Weitz, JI, 2015) |
| "Sepsis is a common condition that is associated with significant morbidity, mortality and health-care cost." | ( McAuley, DF; Shyamsundar, M; Toner, P, 2015) |
| "Sepsis is a severe clinical syndrome characterized by bacterial dissemination and overproduction of inflammatory mediators." | ( Amaral, FA; Costa, VV; Fagundes, CT; Gloria de Souza, Dd; Maximo Prado, MA; Miranda, AS; Prado, VF; Resende, L; Teixeira, AL; Teixeira, MM, 2016) |
| "Sepsis is common in intensive care units (ICU) and is associated with high mortality." | ( Liu, L; Tao, B; Tong, D; Wang, N; Wang, W; Zhang, J, 2015) |
| "Sepsis is a systemic inflammatory response accompanied by excessive production of inflammatory cytokines and cardiovascular dysfunction." | ( Chaugai, S; Chen, C; Chen, J; Lai, J; Ning, Q; Ruan, G; Wang, DW; Yang, L, 2016) |
| "Sepsis is a systemic inflammatory response syndrome caused by an infection and remains as a major challenge in health care." | ( Dehpour, AR; Hassanipour, M; Mousavi, Z; Rahimi, N; Shafaroodi, H, 2015) |
| "Defining sepsis is a difficult task, but what is even more challenging is differentiating infection-induced from non-infection-induced systemic inflammatory response-related multiple organ dysfunction." | ( Becze, Z; Fazakas, J; Molnár, Z, 2015) |
| "Sepsis is a major cause of morbidity and mortality in the emergency department." | ( Baek, KJ; Hong, DY; Jung, HM; Kim, JW; Lee, KR; Paik, JH; Park, SO, 2016) |
| "Sepsis is a complex condition with unacceptable mortality." | ( Han, X; Liu, W; Liu, Z; Zhao, H; Zhao, M, 2016) |
| "Sepsis is commonly associated with brain dysfunction, but the underlying mechanisms remain unclear, although mitochondrial dysfunction and microvascular abnormalities have been implicated." | ( Chisholm, KI; Davies, AL; Duchen, MR; Dyson, A; Ida, KK; Papkovsky, DB; Singer, M; Smith, KJ; Tachtsidis, I, 2016) |
| "coli)-mediated sepsis is a serious illness characterized by the occurrence of thrombocytopenia." | ( Cox, A; Cox, D; McCall, M; Moriarty, RD; Smith, SG, 2016) |
| "Sepsis is a life-threatening clinical condition characterized by uncontrolled inflammatory responses and is a major cause of death in intensive care units." | ( Baek, KS; Jung, YH; Kim, SJ; Lee, SM; Park, HJ, 2016) |
| "Sepsis is a whole-body inflammatory condition with a mortality rate of 30-40%." | ( Choi, JH; Lee, KT; Lim, Y; Seo, YJ; Woo, JH; Yang, YI, 2016) |
| "Sepsis is the response of the host to an infection that produces lesions in its own organs and tissues." | ( Artigas, A; Brunelli, L; Ferrer, R; Goma, G; Navas, A; Pastorelli, R; Ribas Ripoll, V; Romay, E, 2015) |
| "Sepsis is a major health burden worldwide." | ( Bonten, MJ; Cremer, OL; de Stoppelaar, SF; Frencken, JF; Hoogendijk, AJ; Horn, J; Klein Klouwenberg, PMC; Schultz, MJ; van der Poll, T; van Vught, LA; Wiewel, MA; Zwinderman, AH, 2016) |
| "Survivors from sepsis are in an immunosuppressed state that is associated with higher long-term mortality and risk of opportunistic infections." | ( Alves-Filho, JC; Cunha, FQ; de-Deus-Wagatsuma, VM; Figueiredo, F; Leite, CA; Melo, PH; Mota, JM; Nascimento, DC; Noushmehr, H; Rego, EM; Souza, LE; Temporal, J, 2016) |
| "The acute phase of sepsis is characterized by a strong inflammatory reaction." | ( Arts, RJ; Bonten, MJ; Cheng, SC; Cremer, OL; Giamarellos-Bourboulis, EJ; Gresnigt, MS; Joosten, LA; Kox, M; Lachmandas, E; Leentjens, J; Manjeri, GR; Netea, MG; Pickkers, P; Schultz, MJ; Scicluna, BP; van de Veerdonk, FL; van der Meer, AJ; van der Poll, T; Wagenaars, JA; Willems, PH, 2016) |
| "Sepsis is the principal cause of fatality in the intensive care units worldwide." | ( He, W; Jiang, X; Lv, Z; Miao, Z; Qin, X; Wang, Y; Yang, G; Yu, Y; Zheng, Y, 2016) |
| "Sepsis is the leading cause of intensive care unit (ICU) admission." | ( Mat Nor, MB; Md Ralib, A; Pickering, JW, 2017) |
| "Sepsis is characterized by inflammatory and metabolic alterations, which lead to massive cytokine production, oxidative stress and organ dysfunction." | ( Bozza, PT; Burth, P; Castro Faria, MV; Castro-Faria-Neto, HC; Gonçalves-de-Albuquerque, CF; Medeiros-de-Moraes, IM; Oliveira, FM; Silva, AR, 2016) |
| "Sepsis is characterized by a systemic inflammatory response syndrome." | ( Feng, J; Gu, Y; Liang, G; Liu, Z; Qiu, C; Tang, L; Xu, T; Zhang, Y; Zheng, S; Zhu, H, 2016) |
| "Sepsis is a debilitating systemic disease and described as a severe and irregular systemic inflammatory reaction syndrome (SIRS) against infection." | ( Aliomrani, M; Kazemi, AR; Mirzaei, HR; Nekonam, S; Sabzevari, O; Sepand, MR, 2016) |
| "Clinical sepsis is found commonly (53." | ( Afroze, S; Dey, AC; Dey, SK; Hossain, MI; Mannan, MA; Shahidullah, M, 2016) |
| "Bacterial sepsis is a major cause of illness in human immunodeficiency virus infected patients." | ( Alebachew, G; Endris, M; Shiferaw, Y; Teka, B; Tessema, B, 2016) |
| "Pneumonia and sepsis are leading causes of ARDS, the pathophysiology of which includes increased pulmonary microvascular permeability and hemodynamic instability resulting in organ dysfunction." | ( Lee, JY; Lin, K; Linge, HM; Miller, EJ; Ochani, K, 2016) |
| "Sepsis is often characterized by an acute brain inflammation and dysfunction, which is associated with increased morbidity and mortality worldwide." | ( Alexander, JS; Becker, F; Evans, PC; Gavins, FNE; Gillespie, S; Holloway, PM; Nguyen, V; Vital, SA, 2016) |
| "Sepsis is characterized by systemic activation of inflammatory and coagulation pathways in response to infection." | ( Dwivedi, DJ; Fox-Robichaud, AE; Gould, TJ; Liaw, PC; Lysov, Z; Swystun, LL; Zarychanski, R, 2016) |
| "Neutropenic sepsis is associated with a higher AKI risk and concentrations of inflammatory mediators IL-6, IL-8, and G-CSF relative to non-neutropenic patients." | ( Anderson, BJ; Charles, D; Christie, JD; Dunn, TG; Hudock, KM; Kazi, A; Meyer, NJ; Mikkelsen, ME; Reilly, JP; Shashaty, MG; Tommasini, A, 2016) |
| "Preterm sepsis is characterized by systemic bacterial invasion and inflammatory response." | ( Fujioka, K; Kalish, F; Lu, S; Stevenson, DK; Wong, RJ; Wong, S; Zhao, H, 2017) |
| "Sepsis is a serious disease that leads to severe inflammation, dysregulation of immune system, multi-organ failure and death." | ( Chen, Y; Cheng, Q; Cheng, X; Jiao, J; Kong, L; Ma, R; Miao, S; Wang, Z; Yan, Y; Ye, D, 2016) |
| "Sepsis is the leading cause of death among critically ill patients and natural killer T (NKT) cell activation is essential to induce inflammatory cytokine cascade in sepsis." | ( Bi, G; Deng, H; Li, P; Li, S; Luo, Y; Tang, ZH; Wang, D; Wei, Z; Yang, XP; Yao, Y; Zhang, J, 2017) |
| "Background Sepsis is a major public health concern, responsible for more than 750 000 hospitalizations and 200 000 annual deaths in the USA." | ( Baddley, JW; Griffin, RL; Irvin, MR; Mahalingam, M; Moore, JX; Safford, MM; Wang, HE; Zakai, NA, 2016) |
| "Post-splenectomy sepsis is a serious condition with high mortality rates." | ( Claassen, RI; Savelkoul, C; Schouten, MA; Tjan, DH, 2016) |
| "Sepsis is characterized by dysregulated systemic inflammation and cytokine storm." | ( Lee, JY; Lin, K; Linge, HM; Miller, EJ; Ochani, K, 2016) |
| "Sepsis is characterized by microvascular dysfunction and thrombophilia." | ( Apostolakos, MJ; Arning, E; Bottiglieri, T; Doolin, KP; Gough, MS; Mack, CM; Mooney, RA; Morgan, MAM; Pietropaoli, AP; Wexler, O, 2018) |
| "Sepsis is one of the most common causes of neonatal deaths globally." | ( , 2016) |
| "Sepsis is associated with cardiac contractile dysfunction attributed to alterations in Ca handling." | ( Bastos Carvalho, A; Blanco, P; Gonano, LA; López Alarcón, M; Medei, E; Morell, M; Peroba Ramos, I; Sepúlveda, M; Vila Petroff, M; Viotti, M, 2017) |
| "Sepsis is a systemic inflammatory response to pathogens and a leading cause of hospital related mortality worldwide." | ( Gräler, MH; Hemdan, NY; Reimann, CM; Weigel, C, 2016) |
| "Sepsis is a serious medical problem and is one of the main causes of high mortality in intensive care units." | ( Zhang, H; Zong, Y, 2017) |
| "Sepsis is a severe inflammatory response to systemic infection that frequently affects the myocardium." | ( An, R; Li, H; Shen, G; Sun, L; Xi, C; Xu, J; Zhang, S; Zhang, W; Zhao, L, 2016) |
| "Sepsis is a severe generalised infection caused usually by pathogenic bacteria." | ( Fuss, J; Palii, V; Voloboyeva, A, 2016) |
| "Sepsis is characterized by the loss of the perm-selectivity properties of the glomerular filtration barrier (GFB) with consequent albuminuria." | ( Adembri, C; Carlucci, M; Carta, G; De Gaudio, AR; Di Filippo, A; Loriga, B; Novelli, A; Selmi, V; Sgambati, E; Tofani, L; Vitali, L, 2016) |
| "Sepsis is a systemic inflammatory response resulting from the excessive production of pro-inflammatory cytokines, including tumor necrosis factor (TNF)‑α." | ( Chen, GD; Chen, XP; Yu, WD, 2016) |
| "Sepsis is a systemic inflammatory reaction that may lead to multiple organ damage and acute lung injury (ALI)." | ( Chang, N; Han, Z; Li, J; Ye, M; Zhang, J; Zhang, X; Zhang, Y, 2017) |
| "Sepsis is a systemic inflammatory condition resulting from bacterial infections." | ( Bae, JS; Chung, J; Kang, H; Kim, J; Kim, SC; Ku, SK; Na, M; Zhou, W, 2017) |
| "Sepsis is an acute life-threatening multiple organ failure caused by a dysregulated host response to infection." | ( Daum, G; Gräler, MH; Greiwe, G; Nierhaus, A; Poppe, A; Winkler, MS, 2017) |
| "Sepsis is a common condition in the emergency department (ED)." | ( Datta, D; Graham, C; Grahamslaw, J; Gray, AJ; Walker, CA, 2018) |
| "Accordingly, sepsis is now defined as a life-threatening organ dysfunction due to a falsely regulated response of the body to an infection." | ( Schlegel, N, 2017) |
| "Sepsis is one of the major causes of death worldwide when associated with multiple organ failure." | ( Bae, MA; Cho, W; Koo, JY; Lee, DS; Lee, S; Lim, D; Oh, K; Park, SB; Park, Y; Song, JS, 2017) |
| "Sepsis is one of the main causes of death among critically ill patients." | ( Prauchner, CA, 2017) |
| "Sepsis is characterised by an excessive release of inflammatory mediators substantially affecting body composition and physiology, which can be further affected by intensive care management." | ( Eissing, T; Ellger, B; Hempel, G; Horn, D; Lanckohr, C; Meyer, M; Radke, C, 2017) |
| "Sepsis is one of the serious disorders in clinical practice." | ( Dong, JH; Guo, YJ; Li, HR; Liu, J; Luo, T; Wu, F; Zhang, SL; Zhao, L, 2017) |
| "Sepsis is a leading global cause of morbidity and mortality, and is more common at the extremes of age." | ( Eisen, DP; Leder, K; Lockery, J; McBryde, ES; McNeil, JJ; Moore, EM; Pilcher, D; Wolfe, R; Woods, RL, 2017) |
| "ANTISEPSIS is to be conducted between 2012 and 2018." | ( Eisen, DP; Leder, K; Lockery, J; McBryde, ES; McNeil, JJ; Moore, EM; Pilcher, D; Wolfe, R; Woods, RL, 2017) |
| "Sepsis is a systemic inflammatory response to bacterial infection." | ( Choi, WY; Kang, JS; Kim, LK; Kim, YJ; Lee, WB; Yan, JJ; Zhang, Q, 2017) |
| "Sepsis is a major health problem worldwide, with an extremely high rate of morbidity and mortality, partly due to delayed diagnosis during early disease." | ( Andrade, ASR; Cardoso, J; Graziani, AC; Krieger, MA; Lopes, ALK; Marton, S; Mendes, IF; Schluga, PHC; Stets, MI, 2017) |
| "Prognostication in sepsis is limited by disease heterogeneity, and measures to risk-stratify patients in the proximal phases of care lack simplicity and accuracy." | ( Aydin, A; Dziura, JD; Reynolds, J; Swenson, KE; Wira, CR, 2018) |
| "Sepsis is a systemic inflammatory response usually correlated with multi-organ failure." | ( Al-Amran, F; Hadi, NR; Yousif, NG; Zigam, QA, 2018) |
| "Sepsis is a systemic host response to infection, and patients with sepsis are frequently handled in the intensive care unit." | ( Cao, X; Feng, T; Li, H; Liao, X; Wu, Q; Zhang, J; Zhu, T, 2017) |
| "Neonatal sepsis is the third leading cause of deaths for infants in their first month of life." | ( Brown, SC; Coffey, PS, 2017) |
| "Sepsis is defined as the host's deleterious systemic inflammatory response to microbial infections." | ( Chai, X; Gao, L; Guo, Y; Hu, B; Huang, M; Li, Y; Liu, Y; Lu, P; Ren, S; Xie, W; Xu, M; Yan, J; Zeng, S; Zhang, Y, 2017) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection that may affect the brain." | ( Barichello, T; Comim, CM; Dal-Pizzol, F; Ferreira, GK; Freiberger, V; Generoso, JS; Michels, M; Mina, F; Quevedo, J; Streck, EL; Ventura, L, 2017) |
| "Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Khwaja, J, 2017) |
| "Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs and death." | ( Brenner, T; Fleming, T; Morgenstern, J; Nawroth, PP; Schmoch, T; Siegler, BH; Uhle, F; Weigand, MA, 2017) |
| "Sepsis is a deleterious inflammatory response to infection with high mortality." | ( Dubois, LG; Gilchrist, JJ; Ginsburg, GS; Hill, AV; Jaslow, SL; Ko, DC; Ko, ER; Langley, RJ; Moseley, MA; Mturi, N; Mwarumba, S; Njuguna, P; Pirinen, M; Pittman, KJ; Rautanen, A; Rouse, DC; Salinas, RE; Scott, JA; Thompson, JW; Tsalik, EL; Wang, L; Williams, TN; Woods, CW, 2017) |
| "Sepsis is a major cause of mortality in Intensive Care Units." | ( Dong, HL; Han, H; Hou, LC; Hou, ZX; Huang, Y; Pu, ZS; Shao, T; Sun, DD; Wang, XX; Xiong, LZ; Yang, WW; Zhang, EF; Zhang, ZX, 2017) |
| "Sepsis is a systemic inflammatory response syndrome with high mortality, which results from severe infection and can lead to secondary organ dysfunction." | ( Li, Y; Luo, B; Yu, Z, 2017) |
| "Sepsis is a severe syndrome that arises when the host response to an insult is exacerbated, leading to organ failure and frequently to death." | ( Alves-Filho, JC; Andrade, WA; Benevides, L; Bonfá, G; Borges, MC; Cunha, FQ; Dias, MS; Fonseca, DM; Gazzinelli, RT; Gozzi, A; Kanashiro, A; Medina, TS; Silva, JS; Silva, MAB; Souza, MC, 2017) |
| "Sepsis is a life-threatening complication of an infection and remains one of the leading causes of mortality in surgical patients." | ( Chen, X; Chu, L; Fang, Q; He, W; Li, H; Li, N; Qiu, D; Shen, J; Wan, Y; Wang, S; Yang, X; Zhan, B; Zhang, H, 2017) |
| "Sepsis is a complication of an infection which imbalance the normal regulation of several organ systems, including the central nervous system (CNS)." | ( Barichello, T; Bellettini-Santos, T; Budni, J; da Rosa, N; Dal-Pizzol, F; Danielski, LG; Della Giustina, A; Fileti, ME; Florentino, D; Fortunato, JJ; Garbossa, L; Goldim, MP; Martins Laurentino, AO; Mathias, K; Mina, F; Oliveira Junior, AN; Petronilho, F; Zarbato, GF, 2017) |
| "Sepsis is a life-threatening condition that requires urgent care." | ( Dedos, SG; Kalbacher, H; Mavrofrydi, O; Miriagou, V; Papazafiri, P; Promponas, VJ; Samara, P; Tsitsilonis, O; Voelter, W; Zachariadis, M, 2017) |
| "Sepsis is an often lethal syndrome resulting from maladaptive immune and metabolic responses to infection, compromising host homeostasis." | ( Bauer, M; Blankenhaus, B; Cardoso, S; Carlos, AR; Del Barrio, L; Larsen, R; Lindig, S; Mithieux, G; Moita, MR; Rajas, F; Rebelo, S; Schäuble, S; Singh, S; Soares, MP; Weis, S, 2017) |
| "Sepsis is a severe inflammatory response to infection." | ( Hsiung, YC; Hu, YM; Pai, MH; Yeh, SL, 2018) |
| "Sepsis is a life-threatening syndrome accompanied by an overwhelming inflammatory response and organ dysfunction." | ( Chen, J; Cheng, Y; Feng, H; Wang, H; Xu, J; Zhong, Q; Zou, Z, 2017) |
| "Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection with a high mortality." | ( Bi, J; Liu, C; Liu, S; Pang, Q; Wang, S; Zhang, J; Zhang, R, 2017) |
| "Sepsis is a multifactorial syndrome with increasing incidence of morbidity and mortality." | ( Aronson, D; Arow, M; Azzam, ZS; Berger, G; Elias, A; Ismael-Badarneh, R; Kaplan, M; Khoury, J; Makhoul, BF; Mashiach, T, 2017) |
| "Sepsis is a complex process, including a first wave of damage partially due to the body's response to pathogens, followed by a phase of immune cell dysfunction." | ( Boutin, L; Lataillade, JJ; Le Burel, S; Peltzer, J; Thepenier, C, 2017) |
| "Sepsis is a systemic inflammatory response during infection." | ( Lei, M; Lv, R; Xiao, D; Xie, J; Yu, Y; Zhao, J, 2017) |
| "Sepsis is a condition which initiates a cascade of a surge of inflammatory mediators." | ( Chakrabarti, A; Medhi, B; Modi, M; Saikia, UN; Sewal, RK, 2017) |
| "Sepsis is a leading cause of death among patients in the intensive care unit, resulting from multi-organ failure." | ( Damarla, M; Damico, RL; Gao, L; Hassoun, PM; Johnston, LF; Kim, BS; Kolb, TM; Liu, G; Varela, L; Wang, L, 2017) |
| "Sepsis is a life-threatening condition caused by dysregulated inflammatory response to infection with no effective therapy available." | ( Ochani, M; Sharma, A; Wang, P; Yang, WL, 2017) |
| "Sepsis is a systemic inflammatory response syndrome caused by severe infections." | ( Li, W; Qi, ZW; Sun, LC; Wen, QK; Yan, ST; Zhang, GQ; Zhang, HB; Zhi, LD, 2017) |
| "Sepsis is characterized by an innate immune response and the following immune dysfunction which can increase the emergence of secondary infections." | ( Chen, LW; Chen, W; Hong, GL; Lian, J; Lu, ZQ; Mo, QF; Qin, J; Ye, JJ; Zhao, GJ; Zhi, SC, 2017) |
| "Sepsis is a common cause of death in infants and children." | ( Bhankar, H; Gomber, S; Sharma, A; Sharma, S; Sikka, M, 2017) |
| "Sepsis is a potentially lethal condition, and it is associated with platelet alterations." | ( Abdalla, FH; Adefegha, SA; Bertoncheli, CM; Casali, EA; Castilhos, LG; Doleski, PH; Leal, CAM; Leal, DBR; Moritz, CEJ; Pereira, RS; Rezer, JFP; Santos, KF; Santos, RCV; Silveira, KL; Stainki, DR, 2017) |
| "Sepsis is one of the major causes of death worldwide, and is the host response to infection which renders our organs malfunctioning." | ( Chan, YL; Chen, KF; Han, ST; Li, CH; Wu, CC, 2017) |
| "Sepsis is one of the most important causes of death in intensive care units." | ( Mantzarlis, K; Tsolaki, V; Zakynthinos, E, 2017) |
| "Sepsis is a leading cause of mortality in the U." | ( Bar-Or, D; Brody, E; Carrick, M; Lieser, MJ; Rael, LT; Tanner, A, 2018) |
| "Polymicrobial sepsis is the result of an exaggerated host immune response to bacterial pathogens." | ( Batra, S; Jeyaseelan, S; Jin, L, 2017) |
| "Sepsis is one of the main causes of ICU hospitalization worldwide, with a high mortality rate, and is associated with a large number of comorbidities." | ( de Souza Gomes, R; Monteiro, MC; Monteiro, VVS; Navegantes, KC; Reis, JF, 2017) |
| "Sepsis is a major public health problem as well as one of the leading causes of preventable death in children because of failure to recognise the early signs and symptoms and to resuscitate rapidly." | ( Anil, N, 2017) |
| "Sepsis is defined as life-threatening organ dysfunction induced by a disrupted host response to infecting pathogens." | ( Barichello, T; Bonfante, S; Cardoso, T; Danielski, LG; De Carli, RJ; de Oliveira, AN; Fileti, ME; Garbossa, L; Giustina, AD; Goldim, MP; Mathias, K; Petronilho, F; Zarbato, GF, 2018) |
| "Sepsis is a leading cause of mortality among patients in intensive care units across the USA." | ( Campbell, J; Lakshmanan, R; Maulik, N; McFadden, DW; Selvaraju, V; Thirunavukkarasu, M; Wilson, RL, 2017) |
| "Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Dekeyser, T; Duburcq, T; Durand, A; Favory, R; Howsam, M; Neviere, R; Preau, S, 2017) |
| "Sepsis is a potentially fatal condition with high treatment costs, and is especially common among the elderly population." | ( Biyikli, E; Kavalci, C; Kayipmaz, AE, 2018) |
| "Sepsis is a clinical syndrome with no effective protective or therapeutic treatments." | ( Gu, CD; Guo, SD; Li, G; Lian, R; Sun, LC; Yao, Y; Zhang, GQ; Zhang, HB, 2018) |
| "Infection and sepsis are associated with brain white matter injury in preterm infants and the subsequent development of cerebral palsy." | ( Albertsson, AM; Ek, J; Hagberg, H; Hua, S; Jabin, D; Leavenworth, JW; Li, T; Mallard, C; Nazmi, A; Rocha-Ferreira, E; Sobotka, K; Thornton, C; Vontell, R; Wang, X; Zhang, X; Zhou, K; Zhu, C, 2017) |
| "Sepsis is characterized by injury to the microvasculature and the microvascular endothelial cells, leading to barrier dysfunction." | ( Fang, K; Li, W; Long, H; Luo, K; Ma, J; Sun, R; Xie, Y; Xu, B; Zhou, S, 2018) |
| "Sepsis is a clinical condition resulting from a dysregulated immune response to an infection that leads to organ dysfunction." | ( Lehmann, C; Meza, A, 2018) |
| "Urosepsis is defined as a severe disease due to organ failure caused by a urinary tract infection." | ( Forstner, C; Pletz, MW; Wagenlehner, F; Weis, S, 2018) |
| "Sepsis is characterised by organ dysfunction resulting from infection, with no reliable single objective test and current diagnosis based on clinical features and results of investigations." | ( Bellomo, R; de Groot, B; Finfer, S; Fraser, JF; Iredell, J; Keijzers, G; Macdonald, SP; Shetty, A; Tang, B; Thompson, K; Williams, JM, 2018) |
| "Sepsis is acute organ dysfunction in the setting of infection." | ( Arendts, G; Fatovich, DM; Ho, KM; Kinnear, FB; Macdonald, SPJ, 2019) |
| "Sepsis is a life-threatening disease." | ( Chen, D; Du, S; Li, C; Li, H; Liu, X; Mei, L; Miao, J; Wen, Q; Xu, Q; Ye, S, 2018) |
| "The pathology of sepsis is typically characterized by an infection and excessive initial inflammation including a cytokine storm, followed by a state of immune suppression or paralysis." | ( Briegel, J; Choukèr, A; Crucian, B; Feuerecker, M; Guo, A; Kaufmann, I; Pagel, JI; Sams, C; Schelling, G; Strewe, C; Sudhoff, L, 2018) |
| "Urosepsis is defined as a severe disease due to organ failure caused by a urinary tract infection." | ( Forstner, C; Pletz, MW; Wagenlehner, F; Weis, S, 2018) |
| "Sepsis is a condition caused by infection followed by unregulated inflammatory response which may lead to the organ dysfunction." | ( Gupta, E; Jyoti, A; Kaushik, S; Kumar Srivastava, V; Kumar, S; Mehta, SK, 2018) |
| "Sepsis is the dysregulated host response to an infection resulting in life-threatening organ damage." | ( Belsky, JB; Filbin, MR; Lee, PJ; Morris, DC; Rivers, EP, 2018) |
| "Late-onset sepsis is associated with increased rates of mortality and morbidity in newborn infants, in addition to poorer long-term developmental outcomes and increased length of stay and hospital costs." | ( Gordon, A; McMullan, RL, 2018) |
| "Sepsis is a severe systemic condition caused by an excessive inflammatory response to microbial infections, which often results in high mortality." | ( Ahmad, A; Alkharfy, KM; Jan, BL; Raish, M, 2018) |
| "Sepsis is a common diagnosis in critical care with inpatient mortality rates up to 50%." | ( Colby, J; Fissell, WH; Groszek, JJ; Patel, P; Seegmiller, A; Shotwell, M; Verhoven, SM; Verstraete, A, 2018) |
| "Severe sepsis is critical to health and can result in acute renal failure (ARF)." | ( Furuyama, T; Ikeda, S; Maehara, Y; Matsubara, Y; Matsumoto, T; Nakatsu, Y; Nomura, M; Tsuzuki, T; Yoshida, A; Yoshiya, K, 2019) |
| "Sepsis is commonly associated with excessive stimulation of host immune system and result in multi-organ failure dysfunction." | ( Gao, M; Li, Z; Liu, Z; Wang, K; Xiao, X; Yang, B; Yang, M; Zhang, H, 2018) |
| "Sepsis is the syndrome of life-threatening organ dysfunction resulting from dysregulated host response to infection." | ( Chaudhary, NS; Donnelly, JP; Hsu, J; Kim, J; Moore, JX; Safford, MM; Wang, HE, 2018) |
| "Sepsis is associated with an acute deficiency of vitamin C." | ( Marik, PE, 2018) |
| "Sepsis is caused by a dysregulated host response to infection, often associated with acute central nervous system (CNS) dysfunction, which results in long-term cognitive impairment." | ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018) |
| "BACKGROUND Sepsis is known to trigger impaired T cell function, which relates to immunosuppression, contributing to refractory infection and high mortality." | ( Gao, H; Niu, R; Zhang, J; Zhou, Y, 2018) |
| "Sepsis is characterized by the extensive release of cytokines and other mediators." | ( Chen, L; Hong, G; Hu, L; Li, M; Lu, Y; Lu, Z; Qiu, Q; Wu, B; Zhang, Z; Zhao, G; Zhao, L, 2018) |
| "Sepsis is hallmarked by hypercortisolemia, a stress response essential for survival." | ( Derde, S; Dufour, T; Güiza, F; Jenniskens, M; Langouche, L; Pauwels, L; Téblick, A; Van den Berghe, G; Vander Perre, S; Weckx, R, 2018) |
| "BACKGROUND Severe sepsis is among the most common causes of death in Emergency Departments, with more than 30% mortality." | ( Ding, C; Zhao, Y, 2018) |
| "Sepsis is a systemic inflammatory response to pathogenic infection that currently has no specific pharmaceutical interventions." | ( Cho, J; Gharbi, A; Han, HD; Jung, ID; Kang, TH; Kim, Y; Lee, SJ; Lee, Y; Park, HJ; Park, WS; Park, YM, 2018) |
| "Sepsis is a severe systemic inflammatory state in response to infection." | ( Matsathit, U; Mekseepralard, C; Phivthong-Ngam, L; Ratanachamnong, P; Upapan, P; Wongsawatkul, O, 2016) |
| "Sepsis is associated with high early and total in-hospital mortality." | ( Bilker, WB; Coffin, SE; Fuchs, BD; Garrigan, C; Gerber, JS; Han, JH; Han, X; Kelly, BJ; Lautenbach, E; Nachamkin, I; Tolomeo, P; Wise, J, 2018) |
| "Sepsis is one of the main causes of hospitalization and mortality in Intensive Care Units." | ( Branchini, G; Catarina, AV; Da Costa, JC; De Oliveira, JR; Ferreira, F; Gonçalves, CA; Greggio, S; Leite, MC; Luft, C; Marques, EP; Nunes, FB; Rodrigues, L; Venturin, GT; Wartchow, K; Wyse, ATS, 2018) |
| "Sepsis is a life-threatening organ dysfunction caused the dysregulation of host inflammatory response and immunosuppression to infection Early recognition and intervention are hence of paramount importance." | ( Dong, J; Guo, P; Tang, S; Wu, F; Wu, J; Yang, J; Zhang, J; Zhang, S; Zhang, W, 2018) |
| "Sepsis is a life-threatening condition caused by pathogen infection and associated with pyroptosis." | ( Billiar, TR; Cao, L; Jiang, J; Kang, R; Kroemer, G; Liu, J; Ran, Q; Tang, D; Wang, H; Wen, Q; Xie, M; Xie, Y; Zeng, L; Zhu, S, 2018) |
| "Sepsis is newly defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Panknin, HT; Schröder, S; Trautmann, M, 2016) |
| "Sepsis is a life-threatening systemic inflammatory condition triggered as a result of an excessive host immune response to infection." | ( Joseph, J; Mokale, S; Patel, A; Periasamy, H, 2018) |
| "Sepsis is defined as the dysregulated host response to an infection resulting in life-threatening organ dysfunction." | ( Belsky, JB; Jacob, V; Lee, PJ; Sather, JE; Wira, CR, 2018) |
| "Sepsis is a common disease in critical patients, which may lead to myocardial damage, thereby aggravating the severity of the patients' condition, and causing adverse prognosis." | ( Li, L; Yan, J; Zhen, J, 2018) |
| "Sepsis is a major cause of mortality among critically ill patients in the intensive care unit (ICU)." | ( Chen, MH; Han, F; Li, Q; Sun, RH; Tu, YX; Yu, MH, 2018) |
| "Sepsis is a life-threatening organ dysfunction caused by host immune response to infection." | ( Guan, X; Pei, F; Wu, J, 2018) |
| "However, sepsis is a remarkably heterogeneous clinical syndrome, so much so that it is impossible to generalize the clinical results to all septic patients." | ( Guan, X; Pei, F; Wu, J, 2018) |
| "Sepsis is life-threatening organ dysfunction because of a dysregulated host response to infection." | ( Creagh-Brown, B; Forni, LG; Hodgson, L; Potter, EK, 2019) |
| "Sepsis is a life-threatening disease resulted from a dysregulated host immune response to bacterial infections, continuing to cause high morbidity and mortality worldwide." | ( Gao, J; Wang, Z; Zhang, CY, 2018) |
| "Sepsis is a pathology in which patients suffer from a proinflammatory response and a dysregulated immune response, including T cell exhaustion." | ( Aguirre, LA; Avendaño-Ortiz, J; Carballo-Cardona, C; Gómez-Campelo, P; Llanos-González, E; López-Collazo, E; Lozano-Rodríguez, R; Maroun-Eid, C; Martín-Quirós, A; Montalbán-Hernández, K; Toledano, V, 2018) |
| "Sepsis is an acute inflammatory syndrome in response to infection." | ( Broome, AM; Cook, JA; Demcheva, M; Dixit, S; Fan, H; Goodwin, AJ; Halushka, PV; Jones Buie, JN; Vournakis, J; Zhou, Y, 2019) |
| "Sepsis is a life-threatening response to infection often times requiring endotracheal intubation in critically ill patients." | ( Devlin, RJ; Kalil, D, 2018) |
| "Sepsis is one of the most common clinical syndromes that causes death and disability." | ( Choi, DK; Hahn, S; Han, HW; Jee, JH; Jeong, HY; Kim, HK; Lee, DH; Lee, SY; Min, SH; Nam, MO; Yoo, J; Yu, JH, 2018) |
| "Sepsis is a complex syndrome associated with progressive endotoxemic developments, which finally leads to damage of multiple organs, including the heart." | ( Han, Y; Kuai, F; Su, J; Wang, L; Wang, Y; Zhou, S, 2019) |
| "Sepsis is a life-threatening inflammatory syndrome accompanying a bloodstream infection." | ( Aziz, PV; Haslund-Gourley, B; Heithoff, DM; Mahan, MJ; Marth, JD; Millán, JL; Narisawa, S; Nizet, V; Pinkerton, AB; Westman, JS; Yang, WH, 2018) |
| "Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection and characterized by redox imbalance and severe oxidative stress." | ( Cao, P; Dong, X; Fang, Y; Hang, Q; Li, L; Luo, L; Yang, Y; Yin, Z, 2019) |
| "Sepsis is a serious clinical condition with a high mortality rate." | ( Feng, L; Kong, L; Shen, Y; Song, P; Sun, Y; Wu, X; Xu, L; Xu, Q, 2019) |
| "Urosepsis is a very complicated disease with no effective strategy for early diagnosis and treatment." | ( Che, TJ; Wang, N; Wang, YM; Yang, C; Yang, XK, 2018) |
| "Sepsis is a major health complication causing patient mortality and increased healthcare costs." | ( Guo, L; Liu, H; Pei, Z; Sun, Y; Yang, G; Zhang, Y; Zhao, Y, 2019) |
| "Sepsis is a life-threatening organ dysfunction condition response resulting in acute lung injury." | ( Akpinar, E; Cadirci, E; Cinar, I; Dincer, B; Gundogdu, B; Halici, Z; Ugan, RA, 2019) |
| "Sepsis is a potentially fatal illness that can lead to impairment of multiple organs such as liver." | ( Beh-Pajooh, A; Ganbari-Erdi, M; Ghahremani, MH; Hassanzadeh, G; Jeivad, F; Kasirzadeh, S; Mojtahedzadeh, M; Sabzevari, O; Shadboorestan, A; Shalmani, AA, 2018) |
| "Sepsis is a devastating disease that carries an enormous toll in terms of human suffering and lives lost." | ( Marik, PE, 2018) |
| "Sepsis is a big health problem and one of the most common causes of acute lung injury (ALI) leading to high mortality." | ( da Silva, RF; da-Palma-Cruz, M; de Oliveira, APL; Grabulosa, CC; Lino-Dos-Santos-Franco, A; Monteiro, D; Rehim, HMMA, 2019) |
| "Sepsis is a life-threatening condition often associated with a high incidence of multiple organs injury." | ( Borga, C; Brendolan, A; Brocca, A; de Cal, M; Nalesso, F; Pasqualin, C; Pastori, S; Ronco, C; Virzì, GM; Zanella, M, 2019) |
| "Sepsis is an inevitable stage of bacterial invasion characterized by the deregulated inflammatory response, resulting in multiorgan dysfunction syndrome." | ( Hassanein, SS; Mohamed, AS; Sadek, SA; Soliman, AM, 2019) |
| "Sepsis is initiated by the host response to infection with organ damage, increased plasma free fatty acids, high levels of cortisol, massive cytokine production, leukocyte activation, and endothelial dysfunction." | ( Bozza, PT; Carvalho, VF; de Abreu, VHP; de Castro-Faria-Neto, HC; Estato, V; Gonçalves-de-Albuquerque, CF; Kurz, ARM; Medeiros-de-Moraes, IM; Oliveira, FMJ; Silva, AR; Sperandio, M; Torres, RC, 2018) |
| "Sepsis is a serious condition with a high mortality rate worldwide." | ( Chen, P; Gong, S; Gu, T; He, Z; Jiang, Y; Liu, A; Niu, M; Wang, F; Wang, J; Wei, G, 2019) |
| "Sepsis is a leading cause of neonatal mortality in low-resource settings." | ( Bates, MA; Chilufya, MM; Coffin, SE; Cowden, C; Hamer, DH; Kapasa, ML; Localio, AR; Lyondo, A; Machona, S; Munanjala, G; Musyani, CL; Mwananyanda, L; Mwansa, J; Pierre, C, 2019) |
| "Sepsis is a life threatening condition with a high mortality rate, which is characterised by dysregulation of the immune response following infection, leading to organ failure and cardiovascular collapse if untreated." | ( Alcorn, D; Corrigan, DK; Hoskisson, P; Russell, C; Steenson, DP; Vezza, V; Ward, AC, 2019) |
| "Sepsis is the overwhelming systemic immune response to infection, which can result in multiple organ dysfunction and septic shock." | ( Christofidou-Solomidou, M; Drosatos, K; Hoffman, M; Kalliora, C; Koch, WJ; Kokkinaki, D; Kyriazis, ID; Lucchese, AM; Lymperopoulos, A; Madesh, M; Maning, J; Park, JY; Shanmughapriya, S; Tomar, D; Wang, H; Yang, XF, 2019) |
| "Sepsis is characterized by delayed acute phase response and lowered immune tolerance in patients." | ( Burgula, S; Kumar, AP; Mvs, S; Rajkumar, K; Raju, SM; Yadav, AN, 2019) |
| "Sepsis is an overwhelming systemic inflammatory response for which no satisfactory therapeutic drug is available." | ( Chao, CH; Lu, LH; Yeh, TM, 2019) |
| "Sepsis is a serious and life-threatening medical condition with a higher rate of patients' morbidity and mortality and with complications such as acute kidney injury (AKI)." | ( Azimi, S; Baluchnejadmojarad, T; Ghorbanpour, A; Khajevand-Khazaei, MR; Khamse, S; Mohseni-Moghaddam, P; Roghani, M; Salari, S; Sedighnejad, L, 2019) |
| "Maternal sepsis is a significant cause of maternal morbidity and mortality and is a preventable cause of maternal death." | ( Louis, JM; Pacheco, LD; Plante, LA, 2019) |
| "Sepsis is a leading cause of death in hospitalized patients." | ( Joseph, B; Kanashiro, A; Li, Z; Salgado, HC; Shah, R; Shimojo, G; Thompson-Bonilla, MDR; Ulloa, L, 2019) |
| "Sepsis is associated with degradation of the endothelial glycocalyx, releasing heparan sulfate fragments (of sufficient size and sulfation to bind BDNF) into the circulation." | ( Anderson, BJ; Dietz, RM; Ford, JA; Han, X; Herson, PS; Hippensteel, JA; Linhardt, RJ; Liu, J; McMurtry, SA; Meyer, NJ; Orfila, JE; Oshima, K; Schmidt, EP; Su, G; Yang, Y; Yu, Y; Zhang, F, 2019) |
| "Sepsis is an often deadly complication of infection in which systemic inflammation damages the vasculature, leading to tissue hypoperfusion and multiple organ failure." | ( Beiter, RM; Eccles, JD; Fernández-Castañeda, A; Gaultier, A; Rosen, DA; Seki, SM; Woodfolk, JA, 2019) |
| "Sepsis is a bi-phasic inflammatory disease that threatens approximately 30 million lives and claims over 14 million annually, yet little is known regarding the molecular switches and pathways that regulate this disease." | ( Arora, H; Eyford, BA; Jefferies, WA; Johnson, LA; Munro, L; Pfeifer, CG; Welch, I; Wilcox, SM, 2019) |
| "Sepsis is life-threatening and often leads to acute brain damage." | ( Alam, A; Cui, J; Ma, D; Mu, DL; Sun, YB; Wang, DX; Wu, L; Zhang, W; Zhao, H, 2019) |
| "Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Cui, R; Feng, Y; Jia, Y; Li, Z; Liu, C; Miao, R; Qu, K; Zhang, J; Zhang, X, 2019) |
| "Sepsis is a complex pathophysiological event involving systemic inflammatory response syndrome, multiple organ dysfunction syndrome and tissue damage such as acute lung injury (ALI)." | ( Aydin, P; Cadirci, E; Cinar, I; Halici, I; Halici, Z; Sirin, B; Toktay, E, 2019) |
| "Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to an infection." | ( Burkovskiy, I; Lehmann, C; Li, Y; Yeung, P; Zhou, J, 2019) |
| "Sepsis is the most common critical illness in the clinic, with a high incidence and mortality." | ( Cai, H; Cao, Q; Chen, D; Huang, H; Huang, Y; Li, S; Peng, X; Wang, P; Zhong, J, 2019) |
| "Sepsis is a disease responsible for the death of almost all critical patients." | ( Bae, YM; Han, HD; Jang, GY; Jung, ID; Kang, TH; Kim, YS; Lee, SE; Park, HJ; Park, JH; Park, YM; Shin, KC, 2019) |
| "BACKGROUND Sepsis is among the major antecedents of lung injury characterized by mitochondrial dysfunction." | ( Liang, FQ; Lin, Q; Xie, T; Zhang, JR, 2019) |
| "Sepsis is a life-threatening response to systemic infection." | ( Amornphimoltham, P; Leelahavanichkul, A; Star, RA; Yuen, PST, 2019) |
| "Sepsis is characterized by systemic inflammation and widespread organ injury, especially that in the lung." | ( Chen, Z; Li, Q; Shao, Z; Wang, S, 2019) |
| "Sepsis is a life-threatening condition with a high rate of mortality." | ( Fu, J; Li, G; Wu, X; Zang, B, 2019) |
| "Sepsis is a dysregulated immune response normally initiated by an infection." | ( Sweet, RM; Webber, DS; Webber, RJ, 2019) |
| "Sepsis is one of the leading causes of death globally, with significant associated costs." | ( Bush, R; Connelly, CD; Ecoff, L; Failla, KR; Macauley, K, 2019) |
| "Neonatal sepsis is characterized by hyperinflammation causing enhanced morbidity and mortality compared to adults." | ( Costa, I; Denecke, B; Dreschers, S; Lehrke, M; Möllmann, J; Ohl, K; Orlikowsky, T; Roth, J; Tenbrock, K; Viemann, D; Vogl, T, 2019) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Bergmann, A; Di Somma, S; Hur, M; Kim, H; Struck, J, 2019) |
| "Sepsis is an important public health issue and is associated with high treatment costs and high mortality rates." | ( Bueno, RZ; Martins, V; Nagano, TA; Rocha, SL; Stonoga, ETS, 2019) |
| "Sepsis is a common critical condition caused by the body's overwhelming response to certain infective agents." | ( Gou, S; Li, Y; Liu, Z; Meng, Z; Wu, H; Wu, S; Zhao, J, 2019) |
| "Sepsis is a systemic inflammatory response syndrome resulting from infection." | ( Bai, YP; Li, J; Li, TM; Liu, L; Liu, XR; Tang, N; Wang, XB, 2019) |
| "Sepsis is associated with cachexia, but mechanisms are unknown and conventional nutrition approaches are not effective treatments." | ( Cassis, LA; English, V; Ensor, M; Larian, N; Morris, AJ; Stromberg, A; Thatcher, SE, 2019) |
| "Sepsis is a major cause of death and the most common cause of death among critically ill, non-ICU patients." | ( Aidoni, Z; Dardalas, I; Grosomanidis, V; Kouvelas, D; Malliou, F; Milonas, A; Papazisis, G; Pourzitaki, C; Rigopoulos, P; Stamoula, E; Tsaousi, G, 2019) |
| "Background Sepsis is the overwhelming host response to infection leading to shock and multiple organ dysfunction." | ( Bauer, M; Bonios, MJ; de Lucia, C; Drosatos, K; Hoffman, M; Koch, WJ; Kyriazis, ID; Lucchese, AM; Piedepalumbo, M; Schulze, PC, 2019) |
| "Sepsis is a complex of life-threating organ dysfunction in critically ill patients, with a primary infectious cause or through secondary infection of damaged tissues." | ( Chakraborty, S; Halbgebauer, R; Haussner, F; Huber-Lang, M, 2019) |
| "Urosepsis is a severe condition often caused by Escherichia coli that spontaneously have ascended the urinary tract to the kidneys causing pyelonephritis and potentially bacteraemia." | ( Christensen, MG; Fagerberg, SK; Greve, AS; Johnsen, N; Praetorius, HA; Skals, M, 2019) |
| "Sepsis is characterized by life-threatening organ dysfunction caused by a dysregulated host response to infection and affects over 1 million Americans annually." | ( Huang, DT; Kitsios, GD; McVerry, BJ; Morris, A; O'Donnell, CP; Shah, FA; Yende, S; Zhang, Y, 2020) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection with a hospital mortality in excess of 40%." | ( Brinkmann, A; Fiedler, S; Frey, OR; Hagel, S; Hohn, A; Hoyer, H; Kiehntopf, M; Pletz, MW; Roberts, JA; Schlattmann, P, 2019) |
| "Sepsis is a life-threatening condition that may develop to multiple organ failure and septic shock." | ( Li, Y; Shen, H; Wang, Z; Xu, W; Yang, X; Yuan, C; Zhang, L, 2019) |
| "Sepsis is characterized by a severe and disseminated inflammation." | ( Bellaver, B; da Costa, JC; De Bastiani, MA; Gelain, DP; Greggio, S; Klamt, F; Leffa, DT; Lukasewicz Ferreira, PC; Moreira, JCF; Ribeiro, CT; Rocha, AS; Schu, G; Souza, DG; Torres, ILDS; Venturin, GT; Zimmer, ER, 2019) |
| "Sepsis is the systemic inflammatory response caused by infection." | ( Ding, C; Guo, J; Qian, F; Qian, Y; Shen, M; Zhang, W; Zhao, L, 2019) |
| "Sepsis is a set of serious organic manifestations caused by an infection, whose progression culminates in exacerbated inflammation and oxidative stress, poor prognosis, and high hospital costs." | ( Amorim, AT; Brito, LF; Campos, GB; das Neves Selis, N; de Oliveira, MV; de Souza Nascimento, F; de Souza, EP; E Souza, CLS; Júnior, MNS; Marques, LM; Oliveira, HBM; Silva, LSCD; Timenetsky, J; Yatsuda, R, 2019) |
| "Sepsis is a syndrome comprised of a series of life-threatening organ dysfunctions caused by a maladjusted body response to infection with no effective treatment." | ( Liu, Y; Qiu, P; Zhang, J, 2019) |
| "Sepsis is a severe, life-threatening condition primarily caused by the cellular response to infection." | ( He, Y; Shen, Y; Zhang, C, 2019) |
| "Sepsis is a relatively common and deadly condition that constitutes a major challenge to the modern health care system." | ( Feinberg, J; Gluud, C; Jakobsen, JC; Korang, SK; Maagaard, M; Perner, A, 2019) |
| "Sepsis is a leading cause of death and disability worldwide." | ( Liu, Y; Shi, X; Xiao, D; Zhang, D, 2019) |
| "Sepsis is an infection- or toxin-mediated systemic inflammatory syndrome." | ( Jin, JO; Kwak, M; Lee, PCW; Xu, L; Zhang, L; Zhang, W, 2019) |
| "Sepsis is a condition characterized by a severe stage of blood-infection often leading to tissue damage, organ failure and finally death." | ( Altug, H; Belushkin, A; Calvo-Lozano, O; Dey, P; Duempelmann, L; Estevez, MC; Fabri-Faja, N; Lechuga, LM; Pruneri, V; Terborg, RA; Yesilköy, F, 2019) |
| "Sepsis is a complex clinical syndrome leading to severe sepsis and septic shock." | ( Bao, H; Fei, Y; Huang, W; Ronco, C; Sheng, X; Tian, Z; Wang, N; Yang, J; Yin, J; Yu, G, 2019) |
| "Sepsis is a life-threatening organ dysfunction initiated by a dysregulated response to infection, with imbalanced inflammation and immune homeostasis." | ( Chen, Z; Dong, R; Fu, M; Hu, S; Luo, J; Tang, Y; Tu, L; Wang, DW; Xu, X; Yang, Y; Yu, J, 2020) |
| "Sepsis is a potentially fatal systemic inflammatory response syndrome caused by infection." | ( Gao, J; Ge, Y; Huang, T; Jiang, L; Lin, S; Yu, D; Zhang, Y, 2019) |
| "Sepsis is a life-threatening disease that affects 30 million people worldwide each year." | ( Chen, M; Du, H; He, F; Jiang, J; Li, X; Niu, B; Ren, G; Su, Y; Zhang, J, 2019) |
| "BACKGROUND Sepsis is a severe medical condition." | ( Cui, W; Hu, G; Liu, J; Mu, L; Peng, J; Qiao, L, 2019) |
| "BACKGROUND Sepsis is a devastating medical condition." | ( Chen, Y; Cui, W; Hu, G; Liu, J; Mu, L; Qiao, L, 2019) |
| "Sepsis is a severe, life-threatening condition caused primarily by the cellular response to infection." | ( Cao, G; Han, D; Meng, J; Wang, H; Yu, W; Zhang, Y, 2019) |
| "Mortality rate of sepsis is close to 30% to 50% despite better understanding of the pathophysiology of sepsis, and advances in antimicrobial therapy, resuscitation strategies, and mechanical ventilation." | ( Acar, U; Açık, ME; Akbulut, A; Ferah, O; Gökkaya, Z; Tokat, Y; Yenidünya, Ö; Yentür, E, 2019) |
| "Sepsis is a life-threatening clinical syndrome defined as a deregulated host response to infection associated with organ dysfunction." | ( Bauer, M; Clemens, MG; Englert, FA; Galler, K; Gouveia, Z; Heinemann, SH; Neugebauer, U; Pohnert, G; Seidel, RA; Soares, MP; Sponholz, C; Weis, S, 2019) |
| "Nosocomial sepsis is the main problem that preterms have to face during their stay at neonatal intensive care units (NICU)." | ( Bustos, G; Chaves, F; Del Campo, R; Escuder, D; Gómez, M; Jiménez, E; Melgar, A; Moles, L; Moroder, E; Rodríguez, JM; Villa, J, 2019) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host reaction to infection." | ( Dudek, A; Foks, M; Fronczek, J; Nowak-Kózka, I; Polok, K; Szczeklik, W, 2019) |
| "Sepsis is a complex disease that begins with an infectious disorder and causes excessive immune responses." | ( Asghariazar, V; Ghodsi, R; Karimi, A; Karimi, M; Kooshki, F; Tarighat-Esfanjani, A, 2019) |
| "Sepsis is a highly heterogeneous syndrome that is caused by a dysregulated host response to infection." | ( Chen, H; Feng, J; Li, Y; Mao, X; Meng, X; Wang, Y; Xie, K; Yu, Y; Zhang, L; Zhang, Y, 2019) |
| "Sepsis is a major cause of death in hospitalised patients accounting for mortality rates as high as 60% and, hence, is called 'a hidden public health disaster'." | ( Gangadharan, S; Kumar, A; Raveendran, AV, 2019) |
| "Sepsis is hypothesized as an arginine deficient state, with lack of nitric oxide (NO) for adequate microcirculation and local perfusion." | ( Deutz, NE; Luiking, YC; Poeze, M, 2020) |
| "Sepsis is a major cause of patient mortality and morbidity from bacterial infections." | ( Cooper, MA; Gou, Y; Jiang, W; Kang, C; Kim, BYS; Lan, Y; Li, X; Liu, J; Liu, T; Sun, W; Wang, L; Wang, R; Wang, X; Yang, Z; Yu, H; Yu, Y; Yue, K; Zhang, M, 2019) |
| "Sepsis is a life-threatening, dysregulated response to infection." | ( Black, LP; Crandall, M; Ferreira, J; Guirgis, FW; Henson, M; Jones, L; Kalynych, C; Leeuwenburgh, C; Miller, T; Moldawer, LL; Moore, FA; Reddy, ST; Rosenthal, MD; Wu, SS, 2019) |
| "Sepsis is a major cause of death for ICU patients." | ( Li, C; Liu, KX; Liu, WF; Yan, ZZ; Zhang, FL; Zhao, BC; Zhao, J; Zhou, BW, 2020) |
| "Sepsis is one of the most prevalent diseases in the world." | ( Al Zoubi, S; Chiazza, F; Coldewey, SM; Collino, M; Collotta, D; Martin, L; O'Riordan, CE; Purvis, GSD; Stiehler, L; Thiemermann, C; Wissuwa, B, 2019) |
| "Sepsis is characterized by significant alterations in circulating cytokines and adipokines, biologically active molecules produced by the adipose tissue, being implicated in metabolic and inflammatory processes." | ( Christodoulatos, GS; Dalamaga, M; Karampela, I, 2019) |
| "Sepsis is a syndrome of life-threatening organ dysfunction caused by dysregulated host responses to infection." | ( Chen, L; Chen, ZY; Cui, SN; Pan, SW; Qin, L; Shang, Y; Wang, YX; Xiao, HR; Xu, JQ; Yang, XB; Yang, YY; Yuan, SY; Zhou, T, 2019) |
| "Sepsis is an inflammatory response undergoing the complicate pathophysiological changes for host defense against pathogens." | ( Liu, Y; Wang, C; Yu, Y; Zhang, J, 2019) |
| "Sepsis is a life-threatening dysfunction that arises when the body's response to infection causes injury to its own tissues and organs." | ( Ge, X; Shi, M; Tai, Y; Tian, J; Xu, W; Zhao, C; Zhu, G, 2020) |
| "Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately 2." | ( Atak, M; Kostakoglu, U; Mercantepe, T; Topcu, A; Tumkaya, L; Uydu, HA, 2020) |
| "Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to infection." | ( Aziz, M; Denning, NL; Gurien, SD; Wang, P, 2019) |
| "Sepsis is characterized by an early pro-inflammatory phase followed by compensatory anti-inflammatory mechanisms that lead to a late generalized immunosuppression, period where most deaths occur." | ( Duarte, A; Isturiz, M; Montagna, DR; Rearte, B; Ruggiero, RA; Todero, MF, 2020) |
| "Sepsis is a severe pathological condition associated with systemic inflammation, intestinal inflammation, and gastrointestinal barrier dysfunction." | ( De Man, JG; De Winter, BY; Hubens, G; Jorens, PG; Malhotra-Kumar, S; Nullens, S; Pintelon, I; Plaeke, P; Smet, A; Timmermans, JP, 2020) |
| "Sepsis is a physiological, pathological, and biochemical syndrome caused by infection." | ( Tan, Q; Wang, J; Wang, L; Xian, J; Yu, H; Zhang, C; Zhang, X; Zhu, Y, 2019) |
| "Sepsis is a critical disease associated with extremely high mortality." | ( Huang, Q; Li, X; Mu, D; Qu, Y; Sun, X; Yang, X; Zhou, R, 2019) |
| "Sepsis is a host response to systemic inflammation and infection that may lead to multi-organ dysfunction and eventual death." | ( Benkovic, SA; Brichacek, AL; Brown, CM; Chakraborty, S; Dakhlallah, D; Engler-Chiurazzi, EB; Gambill, CA; Jun, S; Millán, JL; Nwafor, DC; Pinkerton, AB; Wang, W, 2020) |
| "Sepsis is a leading cause of death worldwide and a major challenge for physicians to predict and manage." | ( Bergmann, A; Bronton, K; Hartmann, O; Melander, O; Rosenqvist, M; Struck, J, 2019) |
| "Sepsis is a life-threatening organ dysfunction induced by a disrupted host response to infecting pathogens." | ( Carli, RJ; Cidreira, T; Danielski, LG; Denicol, T; Giustina, AD; Goldim, MPS; Joaquim, L; Metzker, KLL; Novochadlo, MM; Petronilho, F; Vieira, T, 2019) |
| "Sepsis is a systemic process with multifactorial pathophysiology that affects most animal species." | ( Andrade, SCS; Claudiano, GS; Coutinho, LL; de Moraes, FR; Gonçalves, FC; Marzocchi-Machado, CM; Moraes, JRE; Moreira, DKT; Mundim, AV; Souza, EC; Yunis-Aguinaga, J, 2020) |
| "Sepsis is a life-threatening disease induced by a systemic inflammatory response, which leads to organ dysfunction and mortality." | ( Ahmad, S; Almatroodi, SA; Arora, S; Dohare, R; Manda, K; Rahmani, AH; Sharma, A; Shriwash, N; Singh, P; Syed, MA, 2019) |
| "Sepsis is one of the most important causes of maternal mortality." | ( Johnson, MR; Lambden, S; Leiper, J; Nasri, NM; Zölner, J, 2020) |
| "Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated host response to infection." | ( Chen, HG; Han, HZ; Li, Y; Xie, KL; Yu, YH, 2020) |
| "Sepsis is a life-threatening disease caused by infection." | ( Chen, D; He, M; Huang, H; Li, C; Li, H; Lin, J; Liu, X; Mei, L; Miao, J; Wen, Q; Xu, Q; Ye, P; Ye, S; Zhang, C; Zhao, K; Zhou, J; Zhou, X, 2019) |
| "Sepsis is a highly complex and lethal syndrome with highly heterogeneous clinical manifestations that makes it difficult to detect and treat." | ( Caraballo, C; Jaimes, F, 2019) |
| "Sepsis is a life-threatening disease without ideal biomarkers." | ( Chen, L; Kou, Q; Xie, W, 2020) |
| "Sepsis is a life-threatening condition caused by a dysregulated host response to infection that remains a huge clinical challenge." | ( Norling, LV; Padovan, MG, 2020) |
| "Sepsis is a health problem of global importance; treatments focus on controlling infection and supporting failing organs." | ( Adhikari, NKJ; Annane, D; Arabi, Y; Archambault, P; Battista, MC; Belley-Côté, É; Bolduc, B; Carbonneau, É; Carr, A; Chassé, M; Clarke, F; Cohen, D; Cook, DJ; D'Aragon, F; Day, AG; Deblois, E; Drouin, C; Guyatt, GH; Heyland, DK; Hunt, M; Iazzetta, J; Kanji, S; Lamontagne, F; Lebrasseur, M; Lellouche, F; Lizotte, P; Marinoff, N; Maslove, D; Masse, MH; McGuinness, S; Ménard, J; Millen, T; Parke, R; Pinto, R; Porteous, R; Rochwerg, B; Sprague, S; Vijayaraghavan, BKT; Walker, S; Watpool, I, 2020) |
| "Sepsis is defined as end-organ dysfunction resulting from the host's inflammatory response to infection." | ( Fu, P; Guo, F; Huang, R; Ma, L; Ren, Q; Tao, S, 2020) |
| "Sepsis is a severe complication following transrectal ultrasound-guided prostate biopsy (TRUSPBx)." | ( Dall'Antonia, M; Eragat, M; Hadjipavlou, M; Hammadeh, MY; Kenny, C; Mulhem, W; Pantelidou, M; Wood, C, 2020) |
| "Sepsis is a systemic inflammatory response syndrome caused by infection." | ( He, Q; Liu, G; Shen, J; Xu, L; Yang, Y; Zhao, M; Zhu, P, 2019) |
| "Sepsis is a systemic inflammatory response syndrome caused by infectious diseases, with cytokines possibly having an important role in the disease mechanism." | ( Hayashi, K; Matsui, H; Nakajima, M; Ohbe, H; Ono, K; Sasabuchi, Y; Yasunaga, H, 2020) |
| "Neonatal sepsis is characterised by dysregulated immune responses." | ( Ashina, M; Fujioka, K; Iijima, K; Ikuta, T; Nishida, K; Okubo, S; Shinohara, M, 2020) |
| "Moreover, sepsis is characterized by a multitude of biochemical interactions and by dynamic changes of the immune system." | ( Bedreag, OH; Bratu, LM; Bratu, T; Dinu, AR; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D, 2020) |
| "Sepsis is associated with exacerbated inflammatory response which subsequently results in multiple organ dysfunction." | ( Badhe, BA; Bhat, BV; Dhas, BB; Kingsley, MK; Parija, SC, 2020) |
| "Sepsis is a complex disorder with very high morbidity and mortality; it can occur when an immune disorder triggers an invasion of pathogens in the host." | ( Ding, Y; Fan, B; Mao, Z; Wang, W; Wang, Y; Wu, J; Yang, Y, 2020) |
| "Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response against infection that triggers systemic inflammatory response syndrome." | ( Kerimoğlu, G; Kural, BV; Malkoç, M; Örem, A; Patan, H; Türedi, S; Yaman, SÖ, 2020) |
| "Sepsis is a systemic inflammatory disease causing life-threatening multi-organ dysfunction." | ( Chen, H; Lai, K; Li, G; Li, Y; Tao, X; Wu, J; Xu, Y; Yuan, Y; Zhang, X; Zou, Z, 2020) |
| "Sepsis is a main reason for death in intensive care units, inflammation is closely related to sepsis." | ( Chen, C; Fu, J; Hu, M; Shao, S; Shi, G; Wu, L; Zang, Y; Zhang, D; Zhang, T; Zhou, Y, 2020) |
| "Sepsis is associated with a decrease in AT levels, and low levels are also associated with the development of multiple organ failure and death." | ( Balk, RA; Kuppy, J; Sungurlu, S, 2020) |
| "Sepsis is a major public health burden resulting in 25% to 30% in-hospital mortality and accounting for over 20 billion dollars of US hospital costs." | ( Cavanaugh, J; Elbaga, Y; Iglesias, J; Patel, VV; Sullivan, JB; Vassallo, AV, 2020) |
| "Neonatal sepsis is a clinical syndrome characterized by symptoms and signs of infection in the first twenty-eight days of life." | ( Al-Ashmawy, GM; El Frargy, MS; Hagag, AA; Yonis, RL, 2021) |
| "Sepsis is a potentially fatal complication of infections and there are currently no effective therapeutic options for severe sepsis." | ( Bae, JS; Kim, H; Kim, IS; Kim, SW; Kwon, OK; Lee, W; Na, DH; Park, EJ; Seo, YK; Yoo, Y, 2020) |
| "Sepsis is a disease with high mortality rate worldwide and inducible nitric oxide (iNOS) induced vascular hyporeactivity plays a key role in it." | ( Cheng, Z; Guo, Y; Li, C; Li, X; Luo, M; Luo, S; Lv, D; Yan, J; Yang, X, 2020) |
| "Sepsis is a heterogeneous clinical syndrome that is complicated commonly by acute kidney injury (sepsis-AKI)." | ( Kerchberger, VE; Ware, LB, 2020) |
| "Sepsis is the leading cause of infectious morbidity and mortality among hospitalized neonates." | ( Coffin, SE; Cowden, C; Hamer, DH; Kapasa, ML; Machona, S; Mitra, N; Mwananyanda, L; Pierre, C; Westling, T, 2020) |
| "Sepsis is a life-threatening organ dysfunction resulting from inflammatory responses instigated by toxins secreted by bacteria." | ( Mokale, SN; Patel, AM; Periasamy, H, 2020) |
| "Sepsis is a life-threatening complication of pneumonia, including coronavirus disease-2019 (COVID-19)-induced pneumonia." | ( Guo, C; Huang, W; Li, R; Li, Y; Qin, Z, 2021) |
| "Sepsis is a life-threatening condition." | ( Chen, G; Gu, Y; Guo, D; Xu, L; Yuan, X, 2020) |
| "Sepsis is associated with global cardiac dysfunction and with high mortality rate." | ( Braumüller, S; Chakraborty, S; Gebhard, F; Huber-Lang, M; Kalbitz, M; Lackner, I; Weber, B, 2020) |
| "Sepsis is a frequent complication in patients in intensive care units (ICU)." | ( Castel, T; Droguet, M; Dubourg, A; Giroux-Metges, MA; Jude, B; Léon, K; Pennec, JP; Tissier, F, 2020) |
| "Sepsis is the leading cause of acute kidney injury in critically ill patients." | ( Good, DW; Sherwood, ER; Tamayo, E; Watts, BA, 2020) |
| "Sepsis is a life-threatening disease in the intensive care unit (ICU)." | ( Deng, Y; Gao, Y; Huang, Y; Lv, D; Xu, X; Zhang, K; Zhu, C, 2020) |
| "Sepsis is a global health issue, and there is a need for effective, low-cost adjunct metabolic treatments." | ( Deane, AM; Fujii, T; Nair, P, 2020) |
| "Sepsis is a life-threatening syndrome which can progress to multiple organ dysfunction with high mortality." | ( Assimakopoulos, SF; Bantouna, D; de Lastic, AL; Gogos, CA; Maroulis, I; Mouzaki, A; Papadopoulou, I; Rodi, M; Zolota, V, 2021) |
| "Sepsis is a serious systemic inflammatory response that primarily affects the lungs and kidneys." | ( Han, S; Qi, B; Wang, X; Zhang, D; Zhou, Y, 2020) |
| "While sepsis is associated with multiple organ damage, acute renal injury represents a hallmark of sepsis." | ( Dyck, JRB; Ferdaoussi, M; Maayah, ZH; Soni, S; Takahara, S, 2021) |
| "Sepsis is an infection-induced aggressive and life-threatening organ dysfunction with high morbidity and mortality worldwide." | ( Chen, Z; Hu, Y; Huang, Y; Mao, L; Pan, H; Pan, J; Pan, X; Qian, S; Xu, S; Xu, W; Ye, Y; Yu, X, 2020) |
| "Neonatal sepsis is a life-threatening inflammatory condition." | ( Bi, J; Du, Z; Li, T; Ren, Y; Wu, R; Zhang, J; Zhang, Y, 2021) |
| "Sepsis is a life-threatening organ dysfunction syndrome arising from uncontrolled inflammatory responses." | ( Li, QY; Qi, L; Xiao, LX; Yu, ED; Yue, HL; Zhang, XL; Zhou, YQ, 2020) |
| "Sepsis is characterized by the host's dysregulated immune response to an infection followed by a potentially fatal organ dysfunction." | ( de Brito Oliveira, AL; de França Gaspar, SL; de Oliveira, JP; de Souza Gomes, R; Monteiro, MC; Monteiro, VVS; Navegantes-Lima, KC; Peres, A; Reis, JF; Rodrigues, CA; Romão, PRT; Sovrani, V; Stutz, H, 2020) |
| "The sepsis is considered as serious clinic-pathological condition related with high rate of morbidity and mortality in critical care settings." | ( Ahmed, MN; Aziz, A; Khan, A; Khan, AU; Khan, S; Muhammad Khan, A; Shal, B, 2020) |
| "Urosepsis is a potentially life-threatening, systemic reaction to uropathogenic bacteria entering the bloodstream of the host." | ( Christensen, MG; Hamilton, ADM; Hvas, AM; Johnsen, N; Praetorius, H; Rubak, P; Skals, M, 2020) |
| "Sepsis is a common clinical critical disease, which is one of the main causes of septic shock and multiple organ dysfunction syndrome (MODS)." | ( Chen, T; Cheng, L; Liang, H; Liu, K; Liu, Y, 2020) |
| "Sepsis is mostly observed in those aged 65 years and over." | ( Igari, H; Kawasakis, Y; Takayanagi, S; Taniguchi, T; Yahaba, M; Yamagishi, K; Yamazaki, S, 2020) |
| "Sepsis is an aberrant systemic inflammatory response mediated by excessive production of reactive oxygen species (ROS) and reactive nitrogen species (RNS)." | ( Choi, C; Jang, K; Kim, JH; Lee, DE; So, Y; Son, W; Yang, CS; Yim, D, 2020) |
| "Sepsis is a life-threatening condition due to a dysregulated immunological response to infection." | ( Barrueta Tenhunen, A; Blokhin, I; Feinstein, R; Hansson, HA; Larsson, A; Massaro, F; Tenhunen, J; van der Heijden, J, 2020) |
| "Sepsis is a life-threatening disorder and leads to organ dysfunction and death." | ( Chen, W; Fu, Q; Li, N; Liu, Y; Zhang, S, 2020) |
| "Sepsis is a deadly complication raised by bacterial pathogens-induced dysregulated innate inflammatory response." | ( Du, P; Jiang, D; Wang, Y, 2020) |
| "Sepsis is currently one of the leading causes of death in intensive care units (ICUs)." | ( Gao, M; Li, ZL; Liu, JJ; Xiao, XF; Yang, BC; Yang, MS, 2020) |
| "Sepsis is the main cause of death in critically ill patients with no effective treatment." | ( Qi, B; Wang, Y; Xie, K; Yu, Y, 2021) |
| "Sepsis is a serious global health issue and a major cause of death and disability." | ( Eisen, DP; Leder, K; Lockery, JE; McBryde, ES; McGuinness, SL; McNeil, JJ; Moore, EM; Nelson, MR; Pilcher, D; Reid, CM; Shastry, A; Wolfe, R; Woods, RL, 2021) |
| "Sepsis is caused by infections associated with life-threatening multiple organ failure (MOF)." | ( Gao, S; Mori, S; Nishibori, M; Takahashi, Y; Teshigawara, K; Wake, H; Wang, D; Yoshii, Y, 2020) |
| "Sepsis care has evolved significantly since the initial early goal-directed therapy (EGDT) trials." | ( Benzoni, N; Ellender, T, 2020) |
| "Sepsis is a severe state of infection with high mortality." | ( Aziz, M; Brenner, M; Murao, A; Wang, P, 2020) |
| "Sepsis is an inflammatory disease characterized by dysregulation of inflammation." | ( Jia, H; Jiao, Y; Li, C; Liang, X; Nie, Z; Zhang, S; Zhang, Y, 2021) |
| "Sepsis is a life-threatening condition caused by the response of the body to an infection, and has recently been regarded as a global health priority because of the lack of effective treatments available." | ( Curley, GF; Kerrigan, SW; Nader, D, 2020) |
| "Sepsis is a severe systemic response to infection; its ensuing organ failure commonly portends an unfavorable prognosis." | ( Huang, Y; Peng, T; Wang, G, 2021) |
| "Sepsis is a significant public health crisis in the United States, contributing to 50% of inpatient hospital deaths." | ( Aaronson, EL; Benzer, TI; Black, L; Filbin, MR; Hayes, BD; Hibbert, KA; Kraus, C; Raja, AS; Sonis, JD; Temin, E; Vareschi, M; White, BA; Wilcox, SR, 2020) |
| "Sepsis is a common and lethal medical problem." | ( Báez, AA; Cochón, L; Libell, N; López, O; Martínez, MDP; Nicolás, JM, 2021) |
| "Sepsis is a severe endothelial dysfunction syndrome." | ( Cheng, Z; Guo, Y; He, A; Hu, S; Luo, S; Pi, Q; Tan, W; Xia, Y; Xu, X; Yan, J, 2021) |
| "Sepsis is characterized by a life-threatening organ dysfunction caused by an unbalanced host response to microbe infection that can lead to death." | ( Bozza, PT; de Castro Faria Neto, HC; de Jesus Oliveira, FM; de Moraes, IMM; Gonçalves-de-Albuquerque, CF; Reis, PA; Rocha, VN; Silva, AR, 2020) |
| "Sepsis is a potentially fatal condition triggered by systemic inflammatory response to infection." | ( Bellot, GL; Chong, TW; Goh, FY; Iskandar, K; Pervaiz, S; Schwarz, H; Tai, JJ; Wang, B; Wong, SC, 2020) |
| "Early diagnosis of sepsis is very important." | ( Liu, D; Liu, WJ; Xing, JY; Yao, B; Zhang, LJ, 2020) |
| "Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation." | ( Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG, 2020) |
| "Sepsis is a life-threatening condition which affects multiple organs including the kidney." | ( Ahmad, SF; Al-Harbi, NO; Alanazi, WA; Alqahtani, F; Alsanea, S; Attia, SM; Ibrahim, KE; Mahmood, HM; Nadeem, A, 2021) |
| "Sepsis is defined as a potentially fatal organ dysfunction caused by a dysregulated host response to infection." | ( da Rocha, MJA; da Silva Junior, JC; de Almeida Beltrão, RL; de Arruda, EPC; de Oliveira Junior, FM; Gomes, DA; Lira, EC, 2021) |
| "Sepsis is often treated with penicillin-binding protein 3 (PBP-3) acting β-lactam antibiotics, such as piperacillin-tazobactam, cefotaxime, and meropenem." | ( Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2020) |
| "Sepsis is one of the main causes of death in critically ill patients." | ( Chai, C; He, M; Kang, F; Nie, J; Zhang, C, 2020) |
| "Sepsis is characterized by a dysregulated immune response, metabolic derangements and bioenergetic failure." | ( Adamzik, M; Bergmann, L; Koos, B; Kreimendahl, S; Marko, B; Nowak, H; Peters, J; Rahmel, T; Rassow, J; Rump, K; Singer, M; Thon, P, 2020) |
| "Sepsis is a severe systemic inflammatory response induced by infection." | ( Nie, Z; Wang, J; Xia, X; Zhang, S; Zhang, Y; Zhao, Y, 2021) |
| "Sepsis is a common disease process encountered by physicians." | ( Gray, S; Hendin, A; Hickey, M; Mok, G; Reardon, P; Yadav, K, 2021) |
| "Sepsis is characterized by a dysregulated immune response to infection characterized by an early hyperinflammatory and oxidative response followed by a subsequent immunosuppression phase." | ( de A Pontes, ACA; de B Oliveira, AL; de Oliveira, AB; de Oliveira, JP; Dorneles, GP; Dos Santos, SM; Júnior, LCR; Monteiro, MC; Monteiro, VVS; Navegantes-Lima, KC; Quadros, LBG; Romão, PRT, 2020) |
| "Sepsis is associated with cardiac dysfunction, which is at least in part due to cardiomyocyte apoptosis." | ( Burgos, JI; Ciocci Pardo, A; González Arbelaez, L; Mosca, S; Sepúlveda, M; Vila Petroff, M, 2020) |
| "Sepsis is a life-threatening condition caused by a dysregulated host-response to inflammation, although it currently lacks a fully elucidated pathobiology." | ( Liu, Q; Ren, J; Wu, J; Wu, X; Zhang, X; Zhao, Y, 2021) |
| "Sepsis is an organ dysfunction caused by a host's unregulated response to infection, causing long-term brain dysfunction with microglial activation, the release of inflammatory components, and mitochondrial changes." | ( Abatti, MR; Barichello, T; Dal-Pizzol, F; Dominguini, D; Generoso, JS; Steckert, AV, 2021) |
| "Sepsis is considered to be one of the major causes of ICU admissions." | ( Bhardwaj, L; Dahiya, A; Deshmukh, K; Gupta, K; Krishan, P; Singh, G; Yadav, S, 2021) |
| "Sepsis is caused by organ dysfunction initiated by an unrestrained host immune response to infection." | ( Gharbi, A; Jung, ID; Kim, DH; Kim, YJ; Lee, KW; Lee, MS; Lee, SJ; Park, YM; You, JS, 2021) |
| "Sepsis is an amplified systemic immune-inflammatory response produced by a microorganism, which involves activation of inflammatory cytokine signaling pathways and oxidative stress." | ( Assreuy, J; Da Silva, EAP; Heimfarth, L; Júnior, LJQ; Marinho, YYM; Menezes, IAC; Oliveira, JYS; Pereira, EWM; Santana, IR; Santos, DMD; Santos, MRVD, 2021) |
| "ICU patients with sepsis are frequently underexposed to piperacillin, which suggests that therapeutic drug monitoring should be strongly recommended for severe infections." | ( Besset, S; Daufresne, P; Fillâtre, P; Flecher, E; Launey, Y; Le Tulzo, Y; Lemaitre, F; Maamar, A; Nesseler, N; Schmidt, M; Tadie, JM; Tattevin, P, 2021) |
| "Bacteremia-induced sepsis is a leading cause of mortality in intensive care units." | ( Alalaiwe, A; Dai, YS; Fang, JY; Liao, CC; Liu, FC; Yang, SC; Yu, HP, 2021) |
| "Sepsis is typically hallmarked by high plasma (free) cortisol and suppressed cortisol breakdown, while plasma adrenocorticotropic hormone (ACTH) is not increased, referred to as 'ACTH-cortisol dissociation." | ( Derde, S; Langouche, L; Pauwels, L; Téblick, A; Van den Berghe, G; Van Oudenhove, T; Vander Perre, S, 2021) |
| "Sepsis is a life-threatening condition, and serum lactate levels have been used to predict patient prognosis." | ( Chen, FC; Cheng, CY; Cheng, HH; Chu, CC; Su, CM; Te Kung, C, 2021) |
| "Sepsis is an emergency medical condition that can lead to death and it is defined as a life-threatening organ dysfunction caused by immune dysregulation in response to an infection." | ( Akamine, EH; Carvalho, MH; Di Bella, D; Echem, C; Ferreira, JPS; Milan, A; Rodrigues, SF; Silva, RNO, 2021) |
| "Sepsis is a common syndrome with substantial morbidity and mortality." | ( Bernard, GR; Brown, SM; Buchman, TG; Busse, LW; Coopersmith, CM; DeWilde, C; Ely, EW; Eyzaguirre, LM; Fowler, AA; Gaieski, DF; Gong, MN; Hager, DN; Hall, A; Hinson, JS; Hooper, MH; Kelen, GD; Khan, A; Levine, MA; Lewis, RJ; Lindsell, CJ; Marlin, JS; Martin, GS; McGlothlin, A; Moore, BL; Nugent, KL; Nwosu, S; Polito, CC; Rice, TW; Ricketts, EP; Rothman, RE; Rudolph, CC; Sanfilippo, F; Sevransky, JE; Viele, K; Wright, DW, 2021) |
| "Sepsis is a systemic inflammatory response syndrome with high mortality." | ( Hong, G; Lu, Z; Sun, F; Wang, Y, 2021) |
| "Sepsis is commonly unrecognized and associated with high mortality, showing the need for reliable and easy-applicable tools to support early recognition." | ( Abdissa, S; Bode, JG; Bosselmann, M; Feldt, T; Fuchs, A; Häussinger, D; Hörner, J; Hurissa, Z; Jensen, BO; Kaasch, AJ; MacKenzie, C; Nordmann, T; Orth, HM; Pfeffer, K; Sorsa, A; Tufa, TB, 2021) |
| "Sepsis is life-threatening organ dysfunction caused by a deregulated host response to infection." | ( Huang, B; Huang, L; Li, C; Li, X; Luo, M; Luo, S; Shen, J; Yan, J; Yang, X, 2021) |
| "Sepsis is a serious medical condition in which immune dysfunction plays a key role." | ( Alemi, SF; Chen, S; Fan, AY; Pan, WX, 2021) |
| "Sepsis is an uncontrolled systemic infection, withcomplex pathophysiology that may result in acute lung organ damage and cause multiple organ failure." | ( Akpinar, E; Aydin, P; Bayraktutan, Z; Dincer, B; Eser, G; Kose, D; Kutlu, Z; Tavaci, T; Yildirim, S; Yuksel, TN, 2022) |
| "Sepsis is a systemic inflammatory response caused by infection, which is a common complication after severe infection, trauma, shock, and surgery, and is also an important factor in inducing septic shock and multiple organ dysfunction syndrome (MODS), and has become one of the important causes of death in critically ill patients." | ( Han, S; Li, Y; Su, X; Zhang, Y, 2021) |
| "Sepsis is a systemic inflammatory response syndrome resulted from severe infection." | ( Li, X; Wang, C; Wang, H; Xu, J; Yu, K; Zhang, J, 2021) |
| "Sepsis is a potentially life-threatening, pathological condition caused by a dysregulated host response to infection." | ( Comish, PB; Kang, R; Tang, D; Wang, N; Wu, R, 2021) |
| "Sepsis is a lethal clinical syndrome that causes multiorgan failure." | ( Lin, MT; Su, LH; Yeh, CL; Yeh, SL, 2021) |
| "Sepsis is common, deadly, and a major challenge to treat." | ( Feinberg, JB; Gluud, C; Jakobsen, JC; Korang, SK; Maagaard, M; Perner, A, 2021) |
| "Sepsis is a systemic inflammatory disease with an unacceptably high mortality rate caused by an infection or trauma that involves both innate and adaptive immune systems." | ( Ahmad, S; Ali Syed, M; Ali, S; Mohsin, M; Tabassum, G, 2021) |
| "Infections and sepsis are common causes of morbidity and mortality, with an increasing incidence worldwide." | ( Birlutiu, V; Boicean, LC, 2021) |
| "Sepsis is one of the leading causes of mortality in intensive care units, and sedation in the intensive care unit during sepsis is usually performed intravenously." | ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021) |
| "Sepsis is a life-threatening condition caused by a dysregulated host response to infection." | ( Asghari Azar, V; Hasanzadeh, M; Karimi, A; Mobasseri, M; Naeini, F; Niazkar, HR; Ostadrahimi, A; Tutunchi, H, 2021) |
| "Sepsis is a systemic inflammatory response to a local severe infection that may lead to multiple organ failure and death." | ( Li, Y; Tan, B; Tian, J; Xie, M; Xu, H; Ye, L; Yi, Q; Zhang, X; Zhang, Y; Zhou, Q; Zhu, J, 2021) |
| "Sepsis is an acute systemic inflammatory disease triggered by bacterial infection leading organ dysfunctions that macrophages are responsible for major triggering of systemic inflammation." | ( Choi, JM; Jeon, SH; Kang, MJ; Kim, SH; Koo, JH, 2021) |
| "Diabetes and sepsis are important causes of morbidity and mortality worldwide, and diabetic patients represent the largest population experiencing post-sepsis complications and rising mortality." | ( Brizzi, MF; Carlin, M; Costantini, E; Porta, M, 2021) |
| "Sepsis is a life-threatening organ dysfunction syndrome, and liver is a susceptible target organ in sepsis, because the activation of inflammatory pathways contributes to septic liver injury." | ( Chen, ZN; Dai, JM; Dai, JY; Guo, WN; Liu, CL; Niu, KW; Tan, YZ; Tao, KS; Yang, XM; Zhang, JJ, 2021) |
| "The treatment of sepsis is still challenging and the liver is an important target of sepsis-related injury." | ( Chen, H; Chen, L; Dou, X; Feng, J; Le, Y; Liu, Z; Lu, D; Pei, L; Wang, C; Zhu, J, 2021) |
| "Sepsis is a life-threatening condition that can lead to several organ failures including kidney." | ( Dai, XG; Duan, ZP; Hu, BQ; Li, Q; Ling, H; Wang, YJ, 2021) |
| "Sepsis is a life-threatening condition caused by heightened host immune responses post infection." | ( Ahmed, SM; Majumdar, S; Nandi, D; Umapathy, S; Verma, T; Yadav, S, 2021) |
| "Sepsis is characterized by persistent systemic inflammation, which can cause multi-organ dysfunction." | ( Chen, Y; Chen, Z; Jin, X; Li, Q; Liu, Y; Shao, Z, 2021) |
| "Sepsis is common in foals and several treatments are used to facilitate recovery." | ( Dembek, KA; Wong, DM; Young, L, 2021) |
| "Sepsis is a complication of an infection which imbalance the normal regulation of several organ systems, including the central nervous system (CNS)." | ( Bagio, E; Barichello, T; Bernades, G; Bonfante, S; da Rosa, N; de Oliveira Junior, AN; Fortunato, JJ; Garbossa, L; Generoso, J; Goldim, MP; Joaquim, L; Lanzzarin, E; Machado, RS; Mathias, K; Metzker, K; Novochadlo, M; Petronilho, F, 2021) |
| "Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation." | ( Abdulnour, RE; Baron, RM; Duvall, MG; Han, J; Jeon, H; Jundi, B; Lee, DH; Levy, BD; Nijmeh, J; Pinilla-Vera, M; Voldman, J, 2021) |
| "Sepsis is a common complication of severe wound injury and infection, with a very high mortality rate." | ( Chen, G; Guo, D; Hang, M; Jin, Q; Kang, Q; Liu, G; Liu, R; Luo, Q; Qu, K; Xu, L, 2021) |
| "Sepsis is a systemic inflammatory response syndrome attributed to infection, while sepsis-induced acute lung injury (ALI) has high morbidity and mortality." | ( Ding, YH; Miao, RX; Zhang, Q, 2021) |
| "Sepsis is a complex infectious syndrome in which neutrophil participation is crucial for patient survival." | ( Amano, MT; Andrade-Oliveira, V; Breda, CNS; Breda, LCD; Câmara, NOS; Carvalho, LADC; Castoldi, A; Cruz, MC; Cunha, FF; Feitosa, ACM; Festuccia, W; Fonseca, MTC; Forni, MF; Fragas, MG; Ghirotto, B; Hiyane, MI; Ignacio, A; Latância, M; Martins da Silva, E; Meotti, FC; Pereira, ADC; Silva, RC; Terra, FF; Venturini, G, 2021) |
| "Sepsis is a life-threatening condition involving a dysregulated immune response to infectious agents that cause injury to host tissues and organs." | ( Dwek, RA; Hill, ML; Martinez, FO; Miller, JL; Perera, N; Sayce, AC; Tyrrell, BE; Zitzmann, N, 2021) |
| "Sepsis is a potentially lethal syndrome resulting from a maladaptive response to infection." | ( Carmeliet, P; De Bosscher, K; Dewaele, S; Dewerchin, M; Dewyse, L; Eggermont, M; Libert, C; Moita, LF; Nuyttens, L; Paakinaho, V; Palvimo, JJ; Sponholz, C; Timmermans, S; Van de Voorde, J; van Grunsven, LA; Van Looveren, K; Van Wyngene, L; Vancraeynest, L; Vanderhaeghen, T; Vandewalle, J; Velho, TR; Wallaeys, C; Weis, S, 2021) |
| "Sepsis is a severe inflammatory disorder that can lead to multiple organ injury." | ( Beng, H; Huang, J; Kuai, Y; Liu, F; Tan, KS; Tan, W; Wang, S; Zhang, R, 2021) |
| "Sepsis is an extensive life-threatening illness that occurs due to an abnormal host response that extends through the initial storm of inflammation and oxidative stress and terminates at the late stage of immunosuppression." | ( Ahmed, AF; Al-Kadi, A; El-Daly, M; El-Tahawy, NFG; Khalifa, MMA, 2022) |
| "Bacterial sepsis is a major cause of mortality resulting from inadequate immune responses to systemic infection." | ( Beck, C; Kretschmer, D; Peschel, A; Schlatterer, K; Schoppmeier, U, 2021) |
| "Sepsis is a dysregulated systemic response to infection and can lead to organ damage and death." | ( Davis, X; Kaplan, J; Lahni, P; Li, C; Stuck, J; Williamson, L, 2021) |
| "Sepsis is an extremely complex clinical syndrome, usually involving an excessive inflammatory response including an overshooting cytokine release that damages tissue and organs of the patient." | ( Burkard, M; Busch, C; Lauer, A; Leischner, C; Michels, H; Niessner, H; Renner, O; Sinnberg, T; Venturelli, S; Vollbracht, C, 2021) |
| "Sepsis is a life-threatening organ dysfunction syndrome arising from infection-induced uncontrolled systemic inflammatory responses." | ( Hashimoto, K; Hashimoto, Y; Ma, L; Qu, Y; Shan, J; Wan, X; Zhang, J, 2021) |
| "Sepsis is a frequent cause of kidney injury." | ( Gao, W; Hu, W; Miao, J; Sun, L; Xu, Z, 2021) |
| "Sepsis is the third most common cause of neonatal mortality globally." | ( Angurana, SK; Dhir, SK; Dutta, S; Gautam, V; Kumar, J; Kumar, P; Munda, VS; Saini, SS; Sundaram, V; Tiewsoh, JBA, 2021) |
| "Sepsis is a serious, heterogeneous clinical entity produced by a severe and systemic host inflammatory response to infection." | ( Artigas, A; Blanch, L; Bringué, J; Camprubí-Rimblas, M; Guillamat-Prats, R; Martinez, ML; Torrents, E, 2021) |
| "Sepsis is a life-threatening condition caused by the dysregulated and overwhelming response to infection, accompanied by an exaggerated pro-inflammatory state and lipid metabolism disturbance leading to sequential organ failure." | ( Borković-Mitić, S; Glumac, S; Grigorov, I; Jasnić, N; Lakić, I; Pavlović, S; Ružičić, A; Stanković, S; Todorović, Z; Tosti, T; Đorđević, J; Đurašević, S; Đurović, S, 2021) |
| "Sepsis is a common condition in the ICU." | ( Assouline, B; Bendjelid, K; Berchtold, L; de Seigneux, S; Elia, N; Faivre, A; Giraud, R; Legouis, D; Pugin, J; Sangla, F; Sgardello, S; Verissimo, T, 2021) |
| "Sepsis is a systemic inflammatory disease; pristimerin exhibits strong antibacterial, anti-inflammatory and antioxidant properties." | ( Li, Y; Xue, W; Zhang, M, 2021) |
| "The pathology of sepsis is extremely complex." | ( Liu, T; Wang, C; Zhang, Y, 2021) |
| "Sepsis is a systemic inflammatory response syndrome, associated with high risk of acute kidney injury (AKI) and in-hospital mortality." | ( He, L; Jiang, X; Long, M; Peng, Z; Su, L; Sun, Z; Yang, C; Zhang, J, 2021) |
| "Sepsis is a potentially fatal systemic inflammatory response and its underlying pathophysiology is still poorly understood." | ( Canizares Cardoso, AP; de Freitas, AMD; Dos Santos, LF; Lovo-Martins, MI; Malvezi, AD; Martins-Pinge, MC; Nakama, RP; Pinge-Filho, P; Scacco, G, 2021) |
| "(1) Background: Sepsis is one of the most common critical care illnesses with increasing survivorship." | ( Laudanski, K, 2021) |
| "Urosepsis is life threatening, unless treated immediately." | ( Anitha, P; Bhat, S; Kandasamy, R; Kanungo, R; Mookkappan, S; Subramanian, A, 2021) |
| "Sepsis is the leading condition associated with acute kidney injury (AKI) in the hospital and intensive care unit (ICU), sepsis-induced AKI (S-AKI) is strongly associated with poor clinical outcomes." | ( Li, Q; Luo, Y; Wang, S; Zhang, Y; Zhao, P; Zhu, J; Zhu, L, 2021) |
| "Sepsis is hallmarked by high plasma cortisol/corticosterone (CORT), low adrenocorticotropic hormone (ACTH), and high pro-opiomelanocortin (POMC)." | ( De Bruyn, L; Derde, S; Langouche, L; Pauwels, L; Téblick, A; Van den Berghe, G; Van Oudenhove, T; Vander Perre, S, 2022) |
| "Sepsis is a major challenge in intensive care unit worldwide and the septic survivors are left with long-term cognitive deficits." | ( Gao, H; He, H; Jun, G; Lu, L; Ruan, W; Song, J; Song, W; Sun, L; Tong, Q; Wang, X; Wang, Y; Wei, P; Yin, Z; Yong, Y; Zou, Y, 2022) |
| "Sepsis is a condition characterized by life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Bonderski, V; Krishnan, K; Rech, MA; Tednes, P; Wassermann, TB, 2022) |
| "Sepsis is a systemic inflammatory syndrome, and acute lung injury (ALI) is one of the most common fatal complications of sepsis." | ( Hu, M; Xu, Y; Yang, J, 2022) |
| "Late onset sepsis is a leading cause of death and morbidity in preterm infants." | ( Allegaert, K; Flint, RB; Kurul, S; Mazela, J; Reiss, IKM; Simons, SHP; Taal, HR, 2021) |
| "Sepsis is considered as a life-threatening organ dysfunction caused by a dysregulated response of the host to an infection." | ( Du, J; Wang, C; Yuan, J, 2021) |
| "Late-onset sepsis is common in extremely low birth weight (ELBW) infants, and it leads to the use of antibiotics to cover resistant organisms, which can be nephrotoxic." | ( Al-Jebawi, Y; Karalic, K; Mhanna, MJ; Shekhawat, P, 2022) |
| "Sepsis is a common cause of death in intensive care unit." | ( Song, WL; Wu, JF, 2021) |
| "Sepsis is a lethal syndrome with T-cell dysregulation, imbalanced inflammatory reactions, and gastrointestinal dysfunction." | ( Chen, KY; Huang, CC; Lee, PC; Lin, MT; Wu, JM; Yang, PJ; Yeh, CL; Yeh, SL, 2022) |
| "Sepsis is a serious cause of morbidity and mortality and yet its pathophysiology remains elusive." | ( Alex, SM; Athri, P; Edathadathil, F; Menon, V; Menon, VP; Moni, M; Prasanna, P; Shetty, M; Srinivasa, G, 2021) |
| "Sepsis is a life-threatening complication of infection that is characterized by a dysregulated inflammatory state and disturbed hemostasis." | ( Chowdhury, S; Happonen, L; Malmström, J; Palm, F; Shannon, O; Wettemark, S, 2022) |
| "Sepsis is considered to be a high-risk factor for cognitive impairment in the brain." | ( Guo, C; Qin, Z; Xiao, X; Zhou, C, 2021) |
| "Neonatal sepsis is a serious condition, where an adequate empiric antibiotic treatment is crucial." | ( Akselsen, AB; Sheth, CC; Veses, V, 2022) |
| "Early detection of sepsis is challenging to achieve with current diagnostic methods, leading to expenditures of $27 billion annually in the United States with significant associated mortality." | ( C Sheridan, D; D Somogyi, R, 2022) |
| "Sepsis is a common cause of emergency department (ED) presentation and hospital admission, accounting for a disproportionate number of deaths each year relative to its incidence." | ( Caldwell, JR; Dahn, C; Jamin, C; Mandola, S; Tang, N; Warstadt, NM, 2022) |
| "Sepsis is an exaggerated host response to an infectious challenge that is associated with significant alterations in vasomotor tone." | ( Stark, RJ, 2022) |
| "Sepsis is defined as life-threatening organ dysfunction in result of the host's dysregulated response to infection and septic shock." | ( Darazam, IA; Entezarmahdi, K; Hakemi, MS; Karimi, A; Koomleh, AA; Mardani, M; Miri, MM; Nassiri, AA; Nobakht, A; Parsa, M; Shahrami, R, 2022) |
| "Sepsis is the final common pathway to death for severe infectious diseases worldwide." | ( Karimi, A; Mahmoodpoor, A; Naeini, F; Najifipour, F; Razmi, H; Sefidmooye Azar, P; Tarighat-Esfanjani, A; Tutunchi, H; Vajdi, M, 2022) |
| "Sepsis is the leading course of morbidity and mortality in critically ill patients." | ( Cao, Y; Chen, F; Han, X; Huang, J; Jiang, Y; Liu, X; Liu, Z; Ma, W; Pei, Y; Xiao, W; Zhu, Y; Zou, L, 2022) |
| "Sepsis is a life-threating organ dysfunction caused by a dysregulated host response to infection." | ( Alfano, F; Caio, G; Catanese, EM; Contini, C; De Giorgi, A; De Giorgio, R; Gambuti, E; Guarino, M; Perna, B; Strada, A; Volpato, S, 2022) |
| "Sepsis is involved in ~ 20% of annual global deaths." | ( Libert, C; Vandewalle, J, 2022) |
| "Sepsis is a common cause for admission to the intensive care unit (ICU), and its incidence has been increasing." | ( Alikiaii, B; Askari, G; Bagherniya, M; Ferns, GA; Keshani, M; Yahyapoor, F, 2022) |
| "Sepsis is one of the major and most common inducements among all causes of ALI." | ( Bai, Y; Cavagnaro, MJ; Li, J; Li, L; Li, Z; Shi, J; Tang, Y; Wang, X; Zhang, Y, 2022) |
| "Sepsis is a host response with life-threatening organ dysfunction caused by an infection." | ( Fan, J; He, ZM; Sun, Y; Wu, Y; Yu, C; Zhang, W; Zhou, Y, 2022) |
| "Sepsis is a pathology accompanied by increases in myeloid cells and decreases in lymphoid cells in circulation." | ( Aibiki, M; Choudhury, ME; Miyaike, R; Nishi, Y; Nishioka, R; Sato, N; Shinnishi, A; Takada, Y; Tanaka, J; Umakoshi, K; Yano, H, 2022) |
| "Sepsis is an important cause of acute kidney injury (AKI)." | ( Jiang, W; Zheng, R, 2022) |
| "One hallmark of sepsis is the reduced number of lymphocytes, termed lymphopenia, that occurs from decreased lymphocyte proliferation or increased cell death contributing to immune suppression." | ( Chen, K; Kitsios, G; Lai, Y; Lee, JS; Li, T; Li, X; Mallmapalli, RK; McVerry, BJ; Nouraie, M; Nyunoya, T; Zhang, Y; Zou, C, 2023) |
| "Sepsis is a life-threatening medical condition caused by infection-triggered aberrant immune responses, leading to host tissue and organ injury." | ( Bai, X; Jie, J; Li, D; Luo, J; Song, L; Zhu, Y, 2022) |
| "Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Bagio, E; Bonfante, S; Cardoso, T; Dacoregio, C; Danielski, LG; de Souza Goldim, MP; Giustina, AD; Joaquim, L; Machado, RS; Mathias, K; Petronilho, F; Pinho, RA; Predroso, GS; Rodrigues, JF; Silveira, PCL; Stork, S; Venturini, LM; Zaccaron, RP; Zarbato, G, 2022) |
| "Sepsis is a dysregulated host inflammatory response to infection potentially leading to life-threatening organ dysfunction." | ( Ellis, CG; Kowalewska, PM; Kowalewski, JE; Milkovich, SL; Sové, RJ; Wang, L; Whitehead, SN, 2022) |
| "Sepsis is a major public healthcare problem." | ( Abd Elrahman, AH; El-Melouk, MS; Fouad, MA, 2022) |
| "Sepsis is an important healthcare concern in India as well as globally." | ( Barasara, S; Chejara, RS; Meena, PD; Meena, VK; Nawal, CL; Singh, A, 2022) |
| "Pediatric sepsis is a significant public health issue." | ( Bhatt, GC; Chakraborty, R; Gulati, K; Kumar, N; Mehta, I; Nair, N; Raina, R; Sethi, SK; Sharma, B; Singh, S, 2022) |
| "Sepsis is capable of causing systemic infections resulting in multiple organ damage." | ( Shao, H; Zhang, S; Zhao, X, 2022) |
| "Sepsis is a heterogeneous syndrome." | ( Lang, Y; Li, S; Wan, X; Yu, H; Zhang, H, 2022) |
| "Today, sepsis is defined as a dysregulated host immune response to microbial invasion leading to end organ dysfunction." | ( Dellinger, RP; Patel, S; Puri, N, 2022) |
| "Sepsis is a potentially life-threatening systemic inflammatory syndrome characterized by dysregulated host immunological responses to infection." | ( Alnasarat, A; Brownstein, MJ; Farooqi, MS; Khenhrani, RR; LeRoith, D; Mathur, N; Mehdi, SF; Metz, CN; Pusapati, S; Roth, J; Sarwar, S; Tracey, KJ; Yang, H, 2022) |
| "Sepsis is a severe reaction and excessive immune response to infection, which can lead to organ dysfunction, and death." | ( Asghariazar, V; Karimi, A; Mahmoodpoor, A; Mobasseri, M; Musazadeh, V; Naeini, F; Niazkar, HR; Tarighat-Esfanjani, A; Tutunchi, H, 2022) |
| "Sepsis is a life-threatening organ dysfunction responsible for nearly 270,000 deaths annually in the United States alone." | ( Gong, S; Sauer, JD; Tong, Y; Wang, Y; Xie, R; Ye, M; Zhao, Y, 2022) |
| "Sepsis is a devastating disease with high morbidity and mortality and no specific treatments." | ( Bastarache, JA; Brophy, CM; Cheung-Flynn, J; Jesse, JJ; Komalavilas, P; Lee, HNR; Meegan, JE; Putz, ND; Shaver, CM; Sidorova, TN; Smith, KD; Tomasek, T; Ware, LB; Yim, TW, 2022) |
| "Sepsis is a common life-threatening pathology." | ( Gong, X; He, Y; Li, Y; Zhou, F, 2022) |
| "Sepsis is a life-threatening disease involving multiorgan dysfunction, prompted by an unregulated host response to infection." | ( Gupta, K; Singh, G; Singh, TG; Sood, A, 2022) |
| "Sepsis is one of the leading causes of acute kidney injury (AKI), and several mechanisms including microcirculatory alterations, oxidative stress, and endothelial cell dysfunction are involved." | ( Assreuy, J; Oliveira, FRMB; Sordi, R, 2022) |
| "Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to an infection." | ( Jain, S; Long, D; McCall, CE; Oh, TS; Quinn, MA; Stacpoole, PW; Zabalawi, M, 2022) |
| "Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Chen, H; Lian, N; Mao, X; Su, Y; Wang, Y; Xie, K; Yu, Y; Zhu, R, 2022) |
| "Sepsis is associated with multiple organ dysfunction, and the brain is particularly vulnerable." | ( Bo, L; Hu, B; Wang, C; Wang, H; Wang, L; Wang, Y; Zhang, D, 2022) |
| "Sepsis is a life-threatening condition caused by an abnormal immune response induced by infection with no approved or specific therapeutic options." | ( Abraham, SJK; Dedeepiya, VD; Ikeue, Y; Ikewaki, N; Iwasaki, M; Nagataki, M; Preethy, S; Raghavan, K; Senthilkumar, R; Surya Prakash, V, 2022) |
| "Sepsis is a syndrome of physiological and biochemical abnormalities induced by an infection that represents a major public health concern." | ( Ariga, SKK; Barbeiro, DF; Bretones, ML; Lima, TM; Sampaio, SC; Soriano, FG, 2022) |
| "Sepsis is a life-threatening disease characterized by a defensive response to damage." | ( Chen, Q; Liu, H; Xia, L; Zhang, H; Zhang, X, 2022) |
| "Sepsis is a systemic inflammatory response syndrome with high mortality and morbidity worldwide." | ( Chen, J; Dai, L; Gu, L; Li, Z; Liao, F; Liu, D; Liu, Y; Luo, P; Tang, H; Wang, J; Xia, F; Xu, C; Yang, F; Zhang, J; Zhang, Q; Zheng, L; Zhu, Y, 2022) |
| "Sepsis is a life-threatening condition of organ dysfunction caused by dysregulated inflammation which predisposes patients to developing cardiovascular disease." | ( Dyck, JRB; Ferdaoussi, M; Maayah, ZH; Martens, MD; Silver, HL; Soni, S; Takahara, S; Ussher, JR, 2022) |
| "Sepsis is an unsolved clinical condition with a substantial mortality rate in the hospital." | ( Ma, T; Yu-Jing, L; Zhang, T, 2022) |
| "Sepsis is a leading cause of neonatal death." | ( Bogaert, D; Bojang, A; de Silva, TI; de Steenhuijsen Piters, WAA; Kanteh, A; Manneh, J; Peno, C; Roca, A; Sanyang, B; Sesay, AK, 2022) |
| "Sepsis is a common critical illness in the Intensive care unit(ICU) and its management and treatment has always been a major challenge in critical care medicine." | ( Gy, Z; N, C; R, G; Xl, L, 2022) |
| "Sepsis is an uncontrolled host response to infection." | ( Huang, X; Lan, Y; Lei, Y; Li, J; Liu, R; Luo, X; Yang, F; Zeng, F, 2022) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, and it accounts for about half of the cases of acute kidney injury (AKI)." | ( Krupa, A; Krupa, MM; Pawlak, K, 2022) |
| "Sepsis is defined as a dysregulated host response to infection, and high-dose melatonin has been proposed as a treatment due to its antioxidant and anti-inflammatory properties." | ( Allen, L; Colin, PJ; Galley, HF; Galt, SP; Webster, NR, 2022) |
| "Sepsis is a heterogeneous syndrome that results in life-threatening organ dysfunction." | ( Boucekine, M; Cereuil, A; Culver, A; Lefebvre, L; Leone, M; Papazian, L; Ronflé, R, 2022) |
| "Sepsis is a life-threatening organ dysfunction." | ( Lazarević, M; Milić, D; Mitić, K; Sokolović, D; Sokolović, DT; Stanojković, Z, 2022) |
| "It is notable that sepsis is the predominant cause of AKI for patients in the intensive care unit and the mortality remains considerably high." | ( Jiang, X; Li, X; Liu, X; Shi, B; Wang, S; Zhou, X, 2022) |
| "Sepsis is a systemic and deleterious host reaction to severe infection." | ( Deng, S; Guo, W; Liu, D; Long, X; Lv, M; Yang, Q, 2022) |
| "Sepsis is a dysregulated host response to infection that can cause widespread effects on other organs including cardiovascular depression, hypotension and organ failure." | ( Al-Janabi, F; Bird, MF; Calo, G; Gallacher-Horley, B; Guerrini, R; Lambert, DG; McDonald, J; McVey, DG; Thompson, JP; Ye, S, 2022) |
| "Sepsis is a major cause of morbidity and mortality in neonatal foals." | ( Barr, B; Dembek, K; Frazer, M; Johnson, L; Moore, C; Timko, K; Toribio, R, 2023) |
| "sepsis is defined as a systemic inflammatory host response syndrome (SIRS) to infection, commonly bacterial." | ( Assenga, EN; Godfrey, E; Majaliwa, E, 2022) |
| "bacterial sepsis is prevalent at Muhimbili National Hospital contributing to 9." | ( Assenga, EN; Godfrey, E; Majaliwa, E, 2022) |
| "Sepsis is a serious problem in felines with a mortality rate ranging from 29-79%." | ( Colodel, EM; De Barros, MA; De Sousa, ATHI; Dos Santos, TÁ; Dutra, V; Jaworski, LTBN; Koiyama, MFG; Mendonça, AJ; Néspoli, PEB; Sousa, VRF, 2022) |
| "Sepsis is often caused by systemic inflammatory responses." | ( Bi, Y; Li, X; Liu, Y; Long, J; Wu, J; Ying, T; You, G; Yu, T; Zhang, L, 2022) |
| "Sepsis is one of the leading causes of death in intensive care units worldwide." | ( Canbolat, N; Erbas, O; Eroglu, E; Ozkul, B; Sever, IH; Sogut, I; Uyanikgil, Y, 2022) |
| "Sepsis is a clinical syndrome characterised by a severe disorder of pathophysiology caused by infection of pathogenic micro-organisms." | ( Huang, T; Li, S; Lyu, J; Xu, F; Yin, H; Zhang, F; Zhang, L; Zheng, X, 2023) |
| "Sepsis is a life-threatening organ dysfunction with devastating consequences, prominent among which is lung damage." | ( Hu, H; Jiang, H; Sun, Y; Wang, Y; Yi, P; Zhang, G; Zhang, K; Zhang, Z, 2022) |
| "Sepsis is an organ dysfunction syndrome caused by the maladjustment of response to infection." | ( Chen, P; Gao, Z; Huang, F; Song, W; Wang, W; Wang, Z; Wu, J; Yang, X, 2022) |
| "Sepsis is associated with a high risk of death, and the crosstalk between gut microbiota and sepsis is gradually revealed." | ( Chen, Y; Deng, F; Hu, JJ; Hu, Z; Huang, ZB; Liu, KX; Lu, CX; Luo, SD; Zhang, FL; Zhou, ZP, 2022) |
| "Neonatal sepsis is one of the leading causes of neonatal deaths in neonatal intensive care units." | ( Ahmed, J; Alhaidari, OI; Razak, A, 2023) |
| "Sepsis is one of the leading cause of death worldwide." | ( Nishibori, M; Ousaka, D, 2022) |
| "Sepsis is one of the major problems encountered in intensive care units, causing organ damage and increasing mortality." | ( Aydın, P; Bolat, İ; Halıcı, Z; Karabulut Uzunçakmak, S; Karakaya, S; Kılıç, CS; Kutlu, Z; Sağlam, YS, 2023) |
| "Sepsis is a life-threatening condition mostly caused by a bacterial infection resulting in inflammatory reaction and organ dysfunction if not treated effectively." | ( Bielicki, JA; Egli, A; Gerber, C; Heller, S; Huber, F; Lang, HP; Meyer, E, 2022) |
| "Sepsis is a systemic disease with severe health consequences, and it was redefined in 2016 as a life-threatening organ dysfunction caused by an abnormal host response to infection and is a global public health priority." | ( Yu, J; Zhang, M; Zheng, R, 2022) |
| "Sepsis is a global medical issue owing to its unacceptably high mortality rate." | ( Chen, H; Chen, W; Chen, Y; Xie, Y; Zhuang, D; Zou, S, 2023) |
| "Sepsis is a global medical issue owing to its unacceptably high mortality rate." | ( Chen, H; Chen, W; Chen, Y; Xie, Y; Zhuang, D; Zou, S, 2023) |
| "Sepsis is a global medical issue owing to its unacceptably high mortality rate." | ( Chen, H; Chen, W; Chen, Y; Xie, Y; Zhuang, D; Zou, S, 2023) |
| "Sepsis is a leading cause of morbidity and mortality in hospitalized patients." | ( Dai, Z; Huang, D; Lei, J; Li, N; Liu, H; Qi, J; Sun, C; Zhou, K, 2022) |
| "Sepsis is a leading cause of morbidity and mortality in hospitalized patients." | ( Dai, Z; Huang, D; Lei, J; Li, N; Liu, H; Qi, J; Sun, C; Zhou, K, 2022) |
| "The severity of sepsis is associated with a higher DIC score according to the parameters proposed by the International Society of Hemostasis and Thrombosis (ISTH) in 2001: platelet count, bleeding time (Quick), D-dimer, and fibrinogen." | ( Diedrich, S; Heidecke, CD; Kersting, S; Keßler, W; Klee, T; van der Linde, J, 2022) |
| "The severity of sepsis is associated with a higher DIC score according to the parameters proposed by the International Society of Hemostasis and Thrombosis (ISTH) in 2001: platelet count, bleeding time (Quick), D-dimer, and fibrinogen." | ( Diedrich, S; Heidecke, CD; Kersting, S; Keßler, W; Klee, T; van der Linde, J, 2022) |
| "Sepsis is a life-threatening condition and remains a major cause of mortality." | ( Jang, HJ; Jang, JH; Jo, KM; Kim, SH; Lee, HK; Lee, JH; No, TH; Park, JH, 2022) |
| "Sepsis is a life-threatening condition and remains a major cause of mortality." | ( Jang, HJ; Jang, JH; Jo, KM; Kim, SH; Lee, HK; Lee, JH; No, TH; Park, JH, 2022) |
| "Sepsis is a life-threatening disease caused by the dis-functioning of the immune response to pathogenic infections." | ( Jiang, S; Lin, T; Qin, T; Wang, L; Zhang, C, 2023) |
| "Sepsis is a life-threatening disease caused by the dis-functioning of the immune response to pathogenic infections." | ( Jiang, S; Lin, T; Qin, T; Wang, L; Zhang, C, 2023) |
| "Sepsis is a syndrome where the dysregulated host response to infection threatens the life of the patient." | ( De la Puente-Díaz de León, V; Delgado-Coello, B; Luna-Reyes, I; Mas-Oliva, J; Pérez-Hernández, EG; Sifuentes-Osornio, J, 2022) |
| "Background: Sepsis is a life-threatening disorder that leads to the induction of inflammatory responses and organ failure." | ( Al-Hashmi, S; Jamshidi-Adegani, F; Rahimi, A; Sadeghizadeh, M; Soudi, S; Vakilian, S, 2023) |
| "Neonatal sepsis is a major cause of morbidity and mortality with a higher burden from the low- and middle-income countries." | ( Bathia, JN; Mukherjee, A; Mukherjee, M; Poddar, S, 2022) |
| "Sepsis is identified as a severe inflammatory disease." | ( Gao, H; Li, S; Liu, C; Yang, YN; Yuan, W, 2023) |
| "Sepsis is responsible for more than 5 million deaths worldwide every year." | ( Atak, M; Batcik, Ş; Mercantepe, F; Mercantepe, T; Topcu, A; Tumkaya, L; Uydu, HA, 2022) |
| "Sepsis is a dysregulation of the immune response to pathogens and has high morbidity and mortality worldwide." | ( Fu, L; Gong, Z; Miron, RJ; Wang, C; Wang, J; Yuan, Q; Zhang, J; Zhang, Y; Zhao, Q, 2023) |
| "Sepsis is one of the most common and lethal conditions in intensive care medicine." | ( Petros, S, 2023) |
| "Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Cao, XY; Huang, YR; Li, HD; Meng, ZF; Shen, XY; Sun, KY; Wang, X; Wu, FP; You, Y, 2023) |
| "Sepsis is a critical illness often encountered in the intensive care unit." | ( Li, X; Sun, Y; Wang, M; Xue, L; Yan, W; Yin, Z; Zhou, Q, 2023) |
| "Sepsis is a lethal syndrome manifested by an unregulated, overwhelming inflammation from the host in response to infection." | ( Arnold, K; Inman, AM; Li, J; Liao, YE; Linhardt, RJ; Liu, J; Pagadala, V; Pawlinski, R; Sellers, R; Xu, D; Xu, Y; Yin, C; Zhang, F, 2023) |
| "Sepsis is a significant public health challenge." | ( Azmanov, H; Ilan, Y; Kalisman, N; Keidar-Haran, T; Kenig, A; Kessler, A; Kolben, Y; Tayri-Wilk, T; Weksler-Zangen, S, 2023) |
| "Sepsis is a systemic inflammatory response to infection, where sepsis-associated acute kidney injury (AKI) is a common morbid disease with a high morbidity and mortality, and however at present no effective therapy exists." | ( Chen, H; Hu, T; Li, Y; Liu, Q; Mu, Y; Tan, Z; Wang, Q; Yan, X; Yang, Y; Zhang, Z, 2023) |
| "Background: Sepsis is a life-threatening medical emergency, frequently complicated with intensive care unit-acquired weakness syndrome (ICU-AW)." | ( Chen, J; Chen, XY; Cong, XX; Huang, M; Sun, YT; Wang, S; Xu, SB; Zheng, LL; Zhou, YT, 2023) |
| "Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by host response disorders due to infection." | ( Chen, W; Lu, Y; Meng, LP; Shi, Y; Wang, XJ; Wu, Q; Xu, XL, 2023) |
| "Sepsis is a serious disease caused by infection." | ( Dai, D; Ding, X; Duan, X; Fang, Y; Han, B; Liu, H; Liu, S; Luo, Y; Shi, X; Sun, T; Wang, D; Wang, H; Wang, Y; Xu, W; Yang, J; Zhang, R; Zhang, S; Zhang, X, 2022) |
| "Sepsis is a syndrome of physiological, pathological, and biochemical disorders with several processes co-occurring; reactive oxygen species (ROS) production and apoptosis are 2 of them." | ( Alberto Stella, C; Alonso, M; Barrea, L; Burgos, H; Chapela, S; Frias-Toral, E; Muryan, A; Muscogiuri, G; Ricart, M; Schiel, A, 2022) |
| "Sepsis is characterized by an overactive inflammatory response." | ( Liu, P; Pan, Q; Wan, M, 2023) |
| "Sepsis is a leading cause of death among critically ill patients, which is defined as life-threatening organ dysfunction caused by a deregulated host immune response to infection." | ( Chang, T; Chen, D; Chen, S; Deng, H; Dong, L; Luo, J; Tang, T; Tang, ZH; Wu, H; Yang, J; Zhang, C; Zhang, P, 2023) |
| "Sepsis is a systemic inflammatory response syndrome caused by an infection in the body, and accompanying acute kidney injury (AKI) is a common complication of sepsis." | ( Chen, Y; Fu, J; Ma, T; Wei, W; Zhang, T; Zhao, J, 2023) |
| "Sepsis is defined as a dysregulated immune response to infection that leads to multiple organ dysfunction." | ( Hu, L; Li, S; Lv, T; Qi, W; Wang, C; Wang, H; Zhang, C, 2023) |
| "Sepsis is a high-incidence disease and demands intensive care." | ( Hu, Q; Li, Y; Liu, H; Lü, M; Wen, C; Xu, X, 2023) |
| "Sepsis is a dreaded complication in patients with postcardiotomy cardiogenic shock, especially ECMO-associated sepsis." | ( Abdullatif, MT; Aboughanima, MA; Albabtain, MA; AlBarak, MM; Arafat, AA; Azar, B; Belghith, M; Elshoura, YA; Gross, I; Hashavya, S; Ohana Sarna Cahan, L; Osman, AA; Reif, S; Tantway, TM, 2023) |
| "Sepsis is a complex syndrome which comes out after infection, characterized by activation of inflammation and infection and has a high morbidity and mortality." | ( Cadirci, E; Cerrah, S; Deveci, Ö; Okcu, N, 2023) |
| "Sepsis is a complex syndrome caused by multiple pathogens and involves multiple organ failure, particularly spleen dysfunction." | ( Chu, M; Dong, J; Dong, Z; Fan, H; Pan, E; Qiang, J; Shi, J; Tan, X; Wang, H; Wang, Y; Xu, B; Yang, Y; Zhang, X, 2023) |
| "Sepsis is defined as a life-threatening organ dysfunction due to a dysregulated host immune response to an infection." | ( Caetano, MAF; Celes, MRN; de Carvalho, MT; de Oliveira, JF; Dos Santos Arruda, F; Pereira, JX; Soave, DF; Tomé, FD; Vieira, BM, 2023) |
| "Sepsis is a potentially life-threatening systemic dysregulatory response to infection, and septic shock occurs when sepsis leads to systemic vasodilation and subsequent tissue hypoperfusion." | ( Bell, TD; Berg, K; Kanjee, Z; Reynolds, EE, 2023) |
| "Sepsis is a common complication of severe pediatric pneumonia, characterized by difficulty in treatment, a high treatment cost, high morbidity and mortality, and poor prognosis." | ( Lu, Y; Song, L, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by the dysregulated response of the host to an infection, and treatments are limited." | ( Cheng, S; Cong, X; Kuang, Y; Liu, Y; Lv, Q; Wang, D; Xie, W; Xu, X; Zhang, Y; Zhu, H, 2023) |
| "Introduction: Sepsis is a dysregulated host response to infection that can lead to life-threatening organ dysfunction." | ( Davis, X; Howell, K; Kaplan, J; Lahni, P; Mukherjee, R; Piraino, G; Sanchez-Gurmaches, J; Stuck, J; Williamson, L; Wolfe, V; Zingarelli, B, 2023) |
| "Sepsis is associated with long-term cognitive impairment and worse psychological and functional outcomes." | ( Bastarache, J; Collar, EM; Ely, EW; Harrison, FE; Jackson, JC; Kiehl, AL; Lindsell, CJ; Mart, MF; Nwosu, S; Sevransky, JE; Williams Roberson, S; Wilson, JE, 2023) |
| "Bacteria-triggered sepsis is characterized by systemic, uncontrolled inflammation in affected individuals." | ( Ding, Y; Du, J; Gao, R; Ge, X; Huang, Y; Li, R; Liao, W; Wang, M; Wang, X; Zhang, F; Zhang, R; Zhao, B, 2023) |
| "Sepsis is an uncontrolled inflammatory response against a systemic infection that results in elevated mortality, mainly induced by bacterial products known as endotoxins, producing endotoxemia." | ( Alt, C; Aravena, C; Cabello-Verrugio, C; Correa, S; Feijóo, CG; Gatica, S; González-Canacer, A; Jiménez-Dinamarca, I; Lin, CP; Prado, Y; Reyes-Martínez, C; Simon, F; Tapia, P; Varela, D, 2023) |
| "Sepsis is a serious systemic inflammatory response to infections." | ( Büyük, B; Gulcin, İ; Kılınç, N; Ovalı, MA; Öztopuz, RÖ; Şehitoğlu, MH, 2023) |
| "Sepsis is a life-threatening condition secondary to infection that evolves into a dysregulated host response and is associated with acute organ dysfunction." | ( Cao, Y; Fang, C; Han, X; Huang, J; Jing, Y; Liu, Z; Ma, W; Pei, Y; Xiao, W, 2023) |
| "Sepsis is among the most dangerous known diseases, resulting from the dysregulation of the innate immune system in a process that is characterized largely by proinflammatory cytokines." | ( Chen, X; Dolin, HH; Franco, JH; Pan, ZK, 2023) |
| "Sepsis is characterized by an acute inflammatory response to infection, often with multiple organ failures, especially severe lung injury." | ( Ding, F; Hu, Y; Zhu, J, 2023) |
| "Sepsis is defined as a life-threatening dysfunction due to a dysregulated host response to infection." | ( Deng, XM; Li, HR; Li, P; Liu, Q; Wang, JF; Wang, Y; Yu, CM; Zhu, CL, 2023) |
| "Sepsis is a severe inflammatory response to infection with an incidence rate exceeding 48 million cases and 11 million sepsis-related deaths yearly." | ( Abdelnaser, M; Alaaeldin, R; Attya, ME; Fathy, M, 2023) |
| "Sepsis is a life-threatening condition characterized by multiorgan dysfunction due to an exaggerated host response to infection associated with a homeostatic failure." | ( Hardy, G; Manzanares, W; Novoa, J, 2023) |
| "Sepsis is a lethal syndrome characterized by systemic inflammation and abnormal coagulation." | ( Alves-Filho, JC; Baik, N; Borges, IN; Brito, LF; Bruno, AS; Ferreira, RG; Grossi, LC; Melo, EM; Miles, LA; Miranda, TC; Nobre, V; Parmer, RJ; Perucci, LO; Queiroz-Junior, CM; Schneider, AH; Silva, CMS; Sousa, LP; Sugimoto, MA; Talvani, A; Tavares, LP; Teixeira, LC; Teixeira, MM; Vago, JP; Zaidan, I, 2023) |
| "Sepsis is a disease with a very high mortality rate, mainly involving an immune-dysregulated response due to bacterial infection." | ( Fan, X; Jia, K; Li, H; Ma, C; Ning, J; Sun, K; Wang, X, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated inflammatory response to infection." | ( Azambuja, JH; Begnini, K; Bertoni, APS; Braganhol, E; da Cruz, LLP; da Silveira, F; de Souza, PO; Gelsleichter, NE; Haas, CB; Hasko, G; Leite, RO; Mohr, KR; Prá, MD; Soares, MS; Spanevello, RM; Wink, MR, 2023) |
| "Sepsis is a serious systemic inflammatory disease that frequently results in death." | ( Chai, L; Dai, Y; Lv, Y; Wang, D; Wei, Z; Yang, H; Zhan, Z, 2023) |
| "Sepsis is a common syndrome in critically ill patients." | ( Chen, M; Chen, S; Li, R; Sun, J; Sun, S; Xia, Y; Yao, C; Zhang, G; Zhang, L; Zhang, N, 2023) |
| "Sepsis is a life-threatening organ dysfunction syndrome resulted from severe infection with high morbidity and mortality." | ( Du, Y; Fang, H; Guo, Y; Li, D; Li, R; Lv, Z; You, J; Yu, L; Zhang, H, 2023) |
| "Sepsis is a complex heterogeneous condition, and the current lack of effective risk and outcome predictors hinders the improvement of its management." | ( Brummaier, T; Chantratita, N; Chaussabel, D; Chomkatekaew, C; Das, S; Garand, M; Preechanukul, A; Rinchai, D; Syed Ahamed Kabeer, B; Tandhavanant, S; Toufiq, M; West, TE; Yimthin, T, 2023) |
| "Sepsis is caused by complex infections, trauma, and major surgery that results in high morbidity and mortality." | ( Chen, J; Gao, N; Liu, XY; Tang, AL; Zhang, GQ, 2023) |
| "Sepsis is a systemic inflammatory response, and vascular leakage associated with acute lung injury (ALI) is an important pathophysiological process during sepsis." | ( Feng, MF; Hou, HM; Li, PW; Piao, XM; Wang, LB; You, LJ; Zhang, WW; Zhang, Y; Zhao, WP, 2023) |
| "Sepsis is a systemic infection affects several organs, which needs novel therapy for the management of it, thus protective effect of Rhoifolin was estimated against sepsis." | ( Ma, Z; Tripathi, AS; Wen, S, 2023) |
| "Sepsis is as a life-threatening organ dysfunction caused by a dysregulated host response to an infection." | ( Bode, C; David, S; Stahl, K, 2023) |
| "Sepsis is a dangerous condition with a high mortality rate." | ( Deng, F; Du, Y; Fan, X; Pan, T; Su, H; Wang, Y; Zhong, X, 2023) |
| "Sepsis is one of the major causes of death worldwide." | ( de Cal, M; De Rosa, S; Fallico, L; Fanton, G; Lorenzin, A; Rassu, M; Risino, B; Ronco, C; Zanella, M; Zanetti, F, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Barreault, S; Charbel, R; Claude, C; Cousin, VL; Durand, P; Marais, C; Miatello, J; Morin, L; Tissières, P, 2023) |
| "Sepsis is identified as a potentially lethal organ impairment triggered by an inadequate host reaction to infection (Sepsis-3)." | ( Pan, S; Shang, Y; Shu, H; Yuan, S; Zhang, P, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Adhikari, N; Chapagain, N; Ghimire, U; Pandey, S; Pradhan, B; Pradhan, S, 2023) |
| "Aim Sepsis is a medical emergency with no definitive treatment." | ( Hashemi, SM; Hosseini, AZ; Khaligh, SG; Khosrojerdi, A; Soudi, S, 2023) |
| "Sepsis is a systemic inflammatory disease caused by multiple pathogens, with the most commonly affected organ being the lung." | ( Dong, R; Gong, S; Huang, L; Huang, M; Jin, Y; Li, F; Li, X; Tang, X; Wang, X; Yang, H; Yu, Y; Zeng, Z, 2023) |
| "Sepsis is intricately linked to intestinal damage and barrier dysfunction." | ( Jianguo, T; Qi, Y; Wang, F; Wang, Z; Zhang, B, 2023) |
| "Sepsis is a serious syndrome, characterized by the excessive release of inflammatory mediators and thermoregulatory changes, being fever the most common sign." | ( Batalhão, ME; Branco, LGS; Cárnio, EC; de Jesus, AA; Filho, MAM; Navegantes, LCC; Passaglia, P; Silva, HB; Trajano, IP, 2023) |
| "Sepsis is the major cause of mortality across intensive care units globally, yet details of accompanying pathological molecular events remain unclear." | ( Bratanis, E; Chao, Y; Grentzmann, A; Karlsson, CAQ; Linder, A; Malmström, E; Malmström, J; Malmström, L; Mohanty, T; Mørch, M; Nizet, V; Shannon, O, 2023) |
| "Sepsis is a life-threatening systemic organ dysfunction caused by the host's unregulated response to a widespread bacterial infection." | ( Cai, C; Dong, F; Huang, Z; Li, X; Lin, J; Luo, L; Luo, Y; Wu, W; Zhou, C, 2023) |
| "Sepsis is the major cause of death in intensive care units." | ( Feng, Z; Huang, L; Kang, Y; Kong, L; Li, M; Ma, A; Wang, Z; Wei, Y; Xiao, F; Zhang, W, 2023) |
| "Sepsis is the result of a dysregulated host response to an infection and causes high morbidity and mortality at the intensive care units worldwide." | ( Libert, C; Vanderhaeghen, T; Vandewalle, J, 2023) |
| "Sepsis is a leading cause of in-hospital mortality resulting from a dysregulated response to infection." | ( Bai, J; Bian, G; Ding, Y; Fang, C; Hou, Z; Huang, J; Li, M; Li, X; Ren, P; Wang, J, 2023) |
| "Sepsis is an extreme and uncontrolled response of the innate immune system to invading pathogenesis." | ( Dashti, F; Karimi, A; Kiani Chalmardi, F; Mahmoodpoor, A; Sanaie, S; Sefidmooye Azar, P; Vajdi, M, 2023) |
| "Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, with a high morbidity and mortality rate." | ( Liu, L; Wang, Z, 2023) |
| "Sepsis is a systemic organ dysfunction caused by infection, and the most affected organ is the lungs." | ( Gao, T; Hu, B; Li, J; Shi, L, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Bindila, L; Esser, LM; Grimmler, M; Masetto, T; Matzenbach, K; Peter, C; Reinhart, M; Reuschel, T; Schneider, K; Tölke, SA, 2023) |
| "Sepsis is is anabnormalhost immune responsecausedbyinfection." | ( Liu, C; Sun, Y, 2023) |
| "Sepsis is characterized by an endotoxin tolerance phenotype that occurs in the stage of infection." | ( Chen, J; Lu, Y; Qin, Y; Shi, J; Xu, F; Xu, K, 2023) |
| "Sepsis is a life-threatening immune disorder resulting from an dysregulated host response to infection." | ( Chen, C; Chen, X; He, Y; Hu, L; Huang, J; Huang, X; Li, S; Wang, G; Wu, K; Wu, Q; Zhou, X, 2023) |
| "Sepsis is one of the life-threatening diseases worldwide." | ( Bae, JS; Choi, SY; Lee, S; Na, AY; Paudel, S; Tan, M, 2023) |
| "Sepsis is associated with several comorbidities in survivors, such as posttraumatic stress disorder (PTSD)." | ( Matias, ME; Radulski, DR; Raymundi, AM; Rodrigues da Silva, T; Stern, CAJ; Zampronio, AR, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by dysregulated host responses to infection." | ( Cui, X; He, X; Leng, Y, 2023) |
| "Sepsis is characterized as an insulin resistant state." | ( Abraham, M; Barillas-Cerritos, J; Deutschman, CS; Mathew, D; Nedeljkovic-Kurepa, A; Taylor, MD, 2023) |
| "Sepsis is a life-threatening problem by organ dysfunction influenced by negative inflammatory responses and stimulated oxidative stress, which most of sepsis patients about 40-60% are accompanied with myocardial injury." | ( Han, W; Ma, X; Si, X; Wang, J, 2023) |
| "Sepsis is a life-threatening medical emergency triggered by excessive inflammation in response to an infection." | ( Ehle, C; He, Y; Heinzel, T; Iyer-Bierhoff, A; Liu, B; Liu, C; Wu, Y; Xing, S, 2023) |
| "Sepsis is a critical dysregulated host response with high mortality and current treatment is difficult to achieve optimal efficacy." | ( Liu, Y; Lu, J; Wang, D; Yan, S; Zong, X, 2023) |
| "Sepsis is a grave medical disorder characterized by a systemic inflammatory response to infection." | ( Cho, YS; Chun, W; Hur, J; Kim, M; Kym, D; Park, J; Yoon, D; Yoon, J, 2023) |
| "Sepsis is an inflammatory disease with high mortality." | ( Lv, X; Shi, X; Xiao, D, 2023) |
| "Sepsis is now recognized as an imbalance in host cellular functions triggered by the invading pathogens, both related to immune cells, endothelial function, glucose and oxygen metabolism, tissue repair and restoration." | ( Arenkiel, B; Hyldegaard, O; Vinkel, J, 2023) |
| "Sepsis is a serious disease with high mortality and has been a hot research topic in medical research in recent years." | ( Su, J; Tong, Z; Wu, S; Zhou, F, 2023) |
| "Sepsis is a significant contributor to organ function damage or failure that results in intestinal dysfunction." | ( Chen, W; Hua, Z; Li, W; Shen, J; Wang, Y, 2023) |
| "Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream." | ( Castellon, M; Esparza, K; Minshall, RD; Oliveira, SD; Onyuksel, H, 2023) |
| "Sepsis is one of the most challenging health conditions worldwide, with relatively high incidence and mortality rates." | ( Capan, M; Jazayeri, A; Yang, CC, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection." | ( Abosaooda, M; Al-Juaifari, M; Hadi, NR; Mueen, RM; Qassam, H, 2023) |
| "Sepsis is a life-threatening organ dysfunction induced by a dysregulated host response to infection." | ( Daixing, Z; Daqian, Z; Ju, F; Junshuai, W; Lili, W, 2023) |
| "Sepsis is a major cause of acute kidney injury (AKI)." | ( Kim, IY; Kim, MJ; Kim, SR; Kim, YS; Lee, DW; Lee, SB, 2023) |
| "Sepsis is one of the most common risk factors for acute respiratory distress syndrome (ARDS)." | ( Gao, Z; Li, C; Liu, L; Ma, S; Qiu, H; Xie, J; Yang, Y, 2023) |
| "Sepsis is a dysregulated systemic inflammatory response caused by infection that leads to multiple organ injury and high mortality without effective treatment." | ( Hu, G; Liao, J; Su, X; Tian, T; Wang, H; Wang, Y; Wu, S; Yan, L; Ye, J; Zhang, C, 2023) |
| "Sepsis is a significant global public health challenge, resulting in millions of human deaths annually." | ( Komura, M; Miyata, S; Yoshimura, R, 2023) |
| "Sepsis is triggered by microbial infection, injury, or even major surgery." | ( Das, UN, 2023) |
| "Sepsis is a highly heterogeneous syndrome normally characterized by bacterial infection and dysregulated systemic inflammatory response that leads to multiple organ failure and death." | ( Gao, J; Hu, Y; Huang, W; Jiang, J; Li, H; Liu, K; Peng, F; Qin, H; Song, Y; Sun, J; Tu, Y; Xu, W; Ye, Y; Zhang, R, 2023) |
| "Sepsis is a systemic inflammatory response syndrome caused by infection, which has no specific drug at present." | ( Chen, Q; Jiang, Y; Liang, X; Wang, T; Xu, Y, 2023) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and is characterized by multiple biological and clinical features." | ( Sun, T; Wang, H; Wang, W, 2023) |
| "Sepsis is a systemic inflammatory response caused by a bacterial infection that often leading to tissue damage, organ failure and death." | ( Chen, F; Hai, W; Liu, J; Liu, Y; Wang, M; Zhang, Y, 2024) |
| "Sepsis is a serious inflammatory response to infection with an annual incidence rate of >48 million cases and 11 million fatalities worldwide." | ( Alaaeldin, R; Attya, ME; Elhamadany, EY; Fathy, M; Mohyeldin, RH; Sharata, EE, 2023) |
| "As sepsis is associated with a 50% increase in mortality, sepsis-induced cardiomyopathy has become a critical topic." | ( Altoraihi, K; Ghafil, FA; Hadi, NR; Hadi, SMH; Majeed, S, 2023) |
| "Urosepsis is a disease with high mortality, and early diagnosis and treatment are important." | ( Aslan, S; Bayrakçı, S; Şahin, A, 2023) |
| "Sepsis is a critical systemic inflammatory syndrome which usually leads to multiple organ dysfunction." | ( Deng, XM; Li, HR; Liu, Q; Liu, ZL; Ren, SC; Sun, CY; Sun, XY; Wang, JF; Wang, Y; Xie, J; Yu, CM; Zhu, CL, 2023) |
| "Sepsis is a medical condition characterized by acute organ dysfunction and uncontrolled inflammation." | ( Guan, Q; Huang, D; Li, A; Li, B; Qin, J; Zhang, C; Zhang, X, 2023) |
| "Sepsis is defined as the dysregulated immune response leading to multi-organ dysfunction and injury." | ( Abanoz, R; Altınışık, YC; Kaya, SA; Kösemehmetoğlu, K; Özçelebi, E; Özmen, F; Songür, HS; Soydan, G, 2023) |
| "Sepsis is a life-threatening disease with a poor prognosis, and metabolic disorders play a crucial role in its development." | ( Du, Y; Hu, Y; Li, Q; Li, T; Liu, L; Lu, H; Luo, X; She, H; Tan, L; Xiang, X; Yang, S, 2023) |
| "Sepsis is a life-threatening disease with limited treatment options, and the inflammatory process represents an important factor affecting its progression." | ( Han, SB; Hong, JT; Kim, B; Lee, HP; Lim, KH; Park, H; Roh, YS; Son, DJ; Yeo, IJ; Yu, JE; Yun, J, 2023) |
| "Sepsis is a major health problem in the United States (US), constituting a leading contributor to mortality among critically ill patients." | ( Bartels, B; Farrar, JD; Mehta, P; Sharma, D; Thoppil, J, 2023) |
| "Sepsis is mostly caused by multiple organ failures and has unique characteristics in burn injuries, which make it the most dangerous complication of burn injuries." | ( Al-Ani, FW; Fahad, HM, 2023) |
| "Although pain and sepsis are comorbidities of intensive care units, reported data on whether pain control by opioid analgesics could alter inflammatory and end-organ damage caused by sepsis remain inconclusive." | ( Abuiessa, SA; Afify, EA; Ayieng'a, EO; El-Gowilly, SM; El-Mas, MM; Elblehi, SS, 2023) |