An inhibitor that interferes with the process of gap junctional intercellular communication.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 35.4002 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 61.3131 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 44.3735 | 8 | 8 |
| Ataxin-2 | Homo sapiens (human) | Potency | 68.1713 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 69.5048 | 2 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 68.1713 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 27.1395 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 68.1713 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 27.1395 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 43.5974 | 3 | 3 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.0126 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 15.2617 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 32.2041 | 11 | 12 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 72.3304 | 2 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 33.8107 | 6 | 9 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 38.6581 | 3 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 36.1690 | 3 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 23.6372 | 4 | 4 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 30.4510 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 49.0259 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 86.1626 | 2 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 40.2286 | 2 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0126 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0126 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 0.4216 | 1 | 1 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.8489 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 70.6326 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 36.0062 | 2 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 43.4064 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 23.3507 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 54.1965 | 3 | 3 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 39.5923 | 3 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 34.2308 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 11.1706 | 2 | 2 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 51.2060 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 26.0044 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 56.1264 | 3 | 4 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 0.4396 | 3 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 19.3889 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 19.3889 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 10.3526 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 6.7710 | 3 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 34.7076 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 22.6910 | 2 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 30.4510 | 1 | 1 |