tetracycline and Malocclusion

Topics: Adolescent; Adult; Bone Resorption; Child; Humans; Malocclusion; Medical History Taking; Models, Dental; Molar; Orthodontic Appliances; Orthodontics, Corrective; Patient Care Planning; Periodontal Prosthesis; Periodontitis; Periodontium; Prognosis; Radiography, Dental; Tetracycline; Tooth Movement Techniques

Topics: Adolescent; Aggressive Periodontitis; Denture Design; Female; Humans; Malocclusion; Orthodontic Appliances, Removable; Orthodontics, Corrective; Tetracycline

Topics: Adult; Combined Modality Therapy; Dental Veneers; Female; Humans; Malocclusion; Tetracycline; Tooth Bleaching; Tooth Discoloration

The correction of malocclusions in juvenile periodontitis (JP) patients completing periodontal therapy is a problem of increasing clinical concern to orthodontists, since many teeth with severe alveolar bone loss in these patients can now be successfully treated without extraction. In this report, fixed edgewise orthodontic therapy was carried out after the completion of periodontal therapy on four JP patients. The orthodontic therapy included extensive intrusion of teeth severely affected by JP. Phase-contrast microscopic analysis of subgingival plaque from orthodontically treated teeth was used to monitor longitudinally the effects of fixed orthodontic bands on the subgingival flora and also to monitor the efficacy of topical and systemic antimicrobial therapy aimed at suppression of suspected periodontopathic bacteria. Orthodontic movement was completed on most periodontally compromised teeth without significant evidence of additional deterioration in periodontal status. However, within the first 6 months of orthodontic band placement, all patients had significant increases in the number of spirochetes and motile rods in their subgingival flora. Three of the patients also developed high levels of crevicular polymorphonuclear leukocytes around orthodontically treated teeth, indicating significant subgingival inflammation. Intensive antimicrobial measures, including topical inorganic salt applications and systemic tetracycline, were helpful in limiting clinical inflammation and subgingival colonization by periodontopathogens during orthodontic therapy. The results demonstrate that successful orthodontic repositioning can be carried out in treated JP patients. In addition, bacteriologic monitoring and chemotherapeutic suppression of periodontal pathogens may be valuable in the prevention of further destructive periodontal disease activity in periodontitis patients undergoing orthodontic therapy.

Topics: Adolescent; Adult; Aggressive Periodontitis; Bacteria; Bicarbonates; Dental Plaque; Female; Humans; Hydrogen Peroxide; Male; Malocclusion; Microscopy, Phase-Contrast; Neutrophils; Orthodontic Appliances; Periodontal Diseases; Sodium; Sodium Bicarbonate; Spirochaetales; Tetracycline; Tooth Movement Techniques

Topics: Adult; Combined Modality Therapy; Delayed-Action Preparations; Drug Implants; Female; Humans; Malocclusion; Patient Care Planning; Periodontitis; Tetracycline; Tooth Movement Techniques

Eleven Macaca irus monkeys with a mixed or a permanent dentition were used in a study of the possible effects of extraoral forward force on the growth of the dentofacial skeleton. An intermittent forward force of 300 Gm. per side was applied, and the effects were analyzed by means of model casts, cephalometric radiographs, tetracycline bone marking, microradiographs, and histologic preparations. The results obtained were as follows: 1. An extraoral forward force caused significant changes in the circum-maxillary sutures and the maxillary tuberosity. 2. It was found that intermittent force of 300 Gm. per side resulted in desirable reactions in the sutures in young monkeys. 3. It was suggested that reactions in the suture might occur as a result of (1) an opening of the suture, (2) stretching of sutural connective tissue fibers, (3) new bone deposition along the stretched fibers, and (4) homeostasis which maintained the sutural width. 4. The maxillary complex showed a positional change with a little counterclockwise rotation. 5. A local reaction was observed histologically in the adult, but the degree was less than that seen in the young monkey. 6. It was considered that a forward movement of the maxillary complex would readily be accomplished by increasing sutural activity as early as possible. 7. Clinically, it was assumed that the hooks attached to the intraoral appliance should be placed as far frontally as possible. The present study seemed to indicate that forward movement of the maxillary complex would be performed with an extraoral anterior-pull appliance. Further investigation should be designed to evaluate a possible skeletal relapse after an orthopedic approach.

Topics: Aging; Animals; Cephalometry; Extraoral Traction Appliances; Face; Female; Frontal Bone; Haplorhini; Macaca; Male; Malocclusion; Mandible; Maxilla; Maxillofacial Development; Microradiography; Orthodontic Appliances, Removable; Palate; Skull; Sphenoid Bone; Temporal Bone; Tetracycline; Tooth Movement Techniques; Zygoma

Topics: Animals; Bone Resorption; Braces; Cephalometry; Haplorhini; Malocclusion; Mandibular Condyle; Maxillofacial Development; Skull; Staining and Labeling; Tetracycline; Tomography; Zygoma

Topics: Anesthesia, Dental; Child; Dysautonomia, Familial; Female; Humans; Malocclusion; Oral Manifestations; Pain; Pediatric Dentistry; Salivation; Surgery, Oral; Tetracycline; Tooth Discoloration

Topics: Alveolar Process; Alveolectomy; Animals; Bone Regeneration; Bone Transplantation; Dogs; Malocclusion; Mandibular Condyle; Mandibular Fractures; Microscopy, Fluorescence; Osteotomy; Tetracycline; Tooth Extraction; Wound Healing