| Member | Definition | Class |
|---|
| tetraiodothyroacetic acid | A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'. | 3,3',5,5'-tetraiodothyroacetic acid |
| thyroxine | The L-enantiomer of thyroxine. | L-thyroxine zwitterion; L-thyroxine |
| triiodothyronine | An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism. | 3,3',5-triiodo-L-thyronine zwitterion; 3,3',5-triiodo-L-thyronine |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 2.2106 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 24.8302 | 1 | 2 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 21.5228 | 3 | 10 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 36.7305 | 2 | 4 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 27.5404 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 22.3943 | 2 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.0104 | 1 | 4 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 46.9600 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 20.4970 | 8 | 13 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 16.8817 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 28.1920 | 4 | 5 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 3.0353 | 2 | 2 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 26.5592 | 4 | 4 |
| G | Vesicular stomatitis virus | Potency | 27.5404 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 16.8008 | 1 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 57.7203 | 2 | 2 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 15.2518 | 1 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 8.1787 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 78.3960 | 2 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 27.5404 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 10.7458 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 27.5404 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 27.5404 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 1.7632 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 62.0146 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.7943 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 43.6667 | 4 | 7 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 0.6663 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 3.3491 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 11.4239 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 17.7976 | 4 | 6 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 23.8591 | 5 | 5 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 35.9650 | 3 | 4 |
| progesterone receptor | Homo sapiens (human) | Potency | 32.8027 | 2 | 3 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 0.9439 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 41.6066 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 18.9449 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 18.8876 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 24.3025 | 2 | 4 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 89.1251 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 13.5194 | 3 | 12 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 55.0388 | 4 | 4 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 18.6467 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 53.1764 | 1 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 34.8952 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 11.4792 | 2 | 2 |