Page last updated: 2024-08-05 11:52:50
C24-steroid
A steroid compound with a structure based on a 24-carbon (cholane) skeleton.
ChEBI ID: 131620
Members (9)
| Member | Definition | Role |
|---|---|---|
| allocholic acid | An allo-bile acid that is 5alpha-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12. | allocholic acid |
| chenodeoxycholic acid | A dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively. | chenodeoxycholic acid |
| cholic acid | A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12. | cholic acid |
| deoxycholic acid | A bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively. | deoxycholic acid |
| hyodeoxycholic acid | A member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6. | hyodeoxycholic acid |
| lithocholic acid | A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action. | lithocholic acid |
| muricholic acid | A group of trihydroxy-5beta-cholanic acids that are the 6,7-diastereoisomers of 3alpha,6,7-trihydroxy-5beta-cholan-24-oic acid. | muricholic acids |
| ursocholic acid | A bile acid that is 5beta-cholan-24-oic acid bearing three hydroxy substituents at positions 3alpha, 7beta and 12alpha. | ursocholic acid |
| ursodeoxycholic acid | A bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones. | ursodeoxycholic acid |
Research
Studies (12,881)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4,293 (33.33) | 18.7374 |
| 1990's | 2,197 (17.06) | 18.2507 |
| 2000's | 2,280 (17.70) | 29.6817 |
| 2010's | 3,027 (23.50) | 24.3611 |
| 2020's | 1,084 (8.42) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,092 (6.63%) | 5.53% |
| Reviews | 1,407 (8.54%) | 6.00% |
| Case Studies | 795 (4.83%) | 4.05% |
| Observational | 42 (0.25%) | 0.25% |
| Other | 13,140 (79.75%) | 84.16% |